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Parkinsonís Research Now: PDF-Funded Study Discovers New Gene Linked to Parkinsonís

Welcome to the latest installment of Parkinson’s Research Now, which provides you with updates on advances made in Parkinson's science.  In each story, we ask “what does it mean?” for a person with Parkinson’s and provide the answers.


Two New Genetic Mutations Linked to Parkinson’s

Using a new, cutting-edge gene sequencing technology, researchers funded in part by PDF, have discovered two new genes, VPS35 and EIF4G1, linked to familial Parkinson’s. The results were reported in the July 14 and September 9 issues of the American Journal of Human Genetics. Could understanding these genes also improve our understanding of Parkinson’s?

Learn More About VPS35
Learn More About EIF4G1


Individuals with Parkinson’s Who Experience Resting Tremor Are Less Likely to Experience Dyskinesia

Are certain people with Parkinson’s more at risk for a common side effect of levodopa, called dyskinesia? A new study published in the August 2011 issue of Archives of Neurology says yes. Find out what your symptoms may say about your risk.
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Structure of Alpha-Synuclein Protein Takes Surprising Twist

Alpha-synuclein is the hallmark of Parkinson’s, but even researchers were surprised by what they saw when they looked at its structure, says a study published in the August 14, 2011 issue of Nature. What can we learn from this surprising twist?
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I hope you will find these reports informative. For more science headlines please visit our website. If you have any additional questions about these reports, please feel free to call PDF’s HelpLine at (800) 457-6676 or email us at


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If you have or believe you have Parkinson’s disease, then promptly consult a physician and follow your physician’s advice. This email is not a substitute for a physician’s diagnosis of Parkinson’s disease or for a physician’s prescription of drugs, treatment or operations for Parkinson’s.