Spotlight on Research
Roy N. Alcalay, M.D.
"Why do some people who carry genetic mutations associated with Parkinson’s disease (PD) never develop PD while others do?" asks Roy N. Alcalay, M.D., a postdoctoral fellow at the Center for Parkinson’s Disease and Other Movement Disorders...
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How do cognitive and axial motor signs correlate in Parkinson's disease? A 6-year prospective study.
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J Neurol 2009 May;
Authors: Miguel Gago, M Garrett, M Fonseca, M Rosas, M Simões, S Vieira, F Botelho
Departments of Neurology and Neurosurgery, Faculdade de Medicina da Universidade do Porto, Hospital de São João E.P.E, Porto, Portugal, miguelfgago@yahoo.com.
Impairment of Parkinson's disease (PD) axial motor signs (AMS) has been described as a risk factor for dementia. Executive dysfunction is an important feature in recently proposed clinical diagnostic criteria for PD dementia. To clarify the relationship between AMS progression and executive cognitive performance, we conducted a 6-year prospective study in PD patients without AMS impairment at baseline. A hospital-based cohort of PD patients (n = 24) without dementia, in the initial motor stage (Hoehn-Yahr
PMID: 19471849 [PubMed - as supplied by publisher]
