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Kim and Libbe Erickson, R.N.

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Understanding Parkinson’s

Motor Symptoms


    Balance and Falls
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Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.
Vivian M Hernández, Daniel J Hegeman, Qiaoling Cui, Daniel A Kelver, Michael P Fiske, Kelly E Glajch, Jason E Pitt, Tina Y Huang, Nicholas J Justice, C Savio Chan
J Neurosci 2015 Aug; 35(34):11830-47
PMID: 26311767 [PubMed - as supplied by publisher]

Molecular cloning, epigenetic regulation, and functional characterization of Prkd1 gene promoter in dopaminergic cell culture models of Parkinson's disease.
Muhammet Ay, Huajun Jin, Dilshan S Harischandra, Arunkumar Asaithambi, Arthi Kanthasamy, Vellareddy Anantharam, Anumantha G Kanthasamy
J Neurochem 2015 Jul;
PMID: 26230914 [PubMed - as supplied by publisher]

Decreased approach behavior and nucleus accumbens immediate early gene expression in response to Parkinsonian ultrasonic vocalizations in rats.
Joshua D Pultorak, Cynthia A Kelm-Nelson, Lauren R Holt, Katherine V Blue, Michelle R Ciucci, Aaron M Johnson
Soc Neurosci 2015 Aug;
PMID: 26313334 [PubMed - as supplied by publisher]

Association of the functional SNP rs2275294 in ZNF512B with risk of amyotrophic lateral sclerosis and Parkinson's disease in Han Chinese.
Xinglong Yang, Quanzhen Zhao, Ran An, Jinhua Zheng, Sijia Tian, Yanming Xu
Amyotroph Lateral Scler Frontotemporal Degener 2015 Aug; :1-6
PMID: 26313240 [PubMed - as supplied by publisher]

Greater motor progression in patients with Parkinson disease who carry LRRK2 risk variants.
Linda P Oosterveld, John C Allen, Ebonne Y L Ng, Soo-Hoon Seah, Kay-Yaw Tay, Wing-Lok Au, Eng-King Tan, Louis C S Tan
Neurology 2015 Aug;
PMID: 26311745 [PubMed - as supplied by publisher]

F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy.
Zhi Dong Zhou, Shao Ping Xie, Sushmitha Sathiyamoorthy, Wuan Ting Saw, Tan Ye Sing, Shin Hui Ng, Heidi Pek Hup Chua, Alyssa Mei Yan Tang, Fathima Shaffra, Zeng Li, Hongyan Wang, Patrick Ghim Hoe Ho, Mitchell Kim Peng Lai, Dario C Angeles, Tit Meng Lim, Eng King Tan
Hum Mol Genet 2015 Aug;
PMID: 26310625 [PubMed - as supplied by publisher]

Conformational heterogeneity of the Roc domains in C. tepidum Roc-COR and implications for human LRRK2 Parkinson mutations.
Katharina Rudi, Franz Y Ho, Bernd Karl Gilsbach, Henderikus Pots, Alfred Wittinghofer, Arjan Kortholt, Johann P Klare
Biosci Rep 2015 Aug;
PMID: 26310572 [PubMed - as supplied by publisher]

Novel P-TEN-induced putative kinase 1 (PINK1) variant in Indian Parkinson's disease patient.
Tamali Halder, Janak Raj, Vivek Sharma, Parimal Das
Neurosci Lett 2015 Aug; 605:29-33
PMID: 26282903 [PubMed - as supplied by publisher]

Accumulation of amyloid-? in the cerebellar cortex of essential tremor patients.
Eric Béliveau, Cyntia Tremblay, Émilie Aubry-Lafontaine, Sarah Paris-Robidas, Charlotte Delay, Chris Robinson, Les Ferguson, Ali H Rajput, Alex Rajput, Frédéric Calon
Neurobiol Dis 2015 Aug; 82:397-408
PMID: 26253607 [PubMed - as supplied by publisher]

Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression.
Anastasia G Henry, Soheil Aghamohammadzadeh, Harry Samaroo, Yi Chen, Kewa Mou, Elie Needle, Warren D Hirst
Hum Mol Genet 2015 Aug;
PMID: 26251043 [PubMed - as supplied by publisher]

?-Synuclein and nonhuman primate models of Parkinson's disease.
Scott C Vermilyea, Marina E Emborg
J Neurosci Methods 2015 Aug; 255:38-51
PMID: 26247888 [PubMed - as supplied by publisher]

Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice.
Vera L Bonilha, Brent A Bell, Mary E Rayborn, Xiaoping Yang, Charlie Kaul, Gregory H Grossman, Ivy S Samuels, Joe G Hollyfield, Chengsong Xie, Huaibin Cai, Karen G Shadrach
Exp Eye Res 2015 Jul; 139:22-36
PMID: 26215528 [PubMed - as supplied by publisher]

Genetic analysis of SLC41A1 in Chinese Parkinson's disease patients.
Ling Wang, Lan Cheng, Nan-Nan Li, Wen-Juan Yu, Xiao-Yi Sun, Rong Peng
Am J Med Genet B Neuropsychiatr Genet 2015 Aug;
PMID: 26308152 [PubMed - as supplied by publisher]

Transcriptional dysregulation of inflammatory/immune pathways after active vaccination against Huntington's disease.
Arlene I Ramsingh, Kevin Manley, Yinghui Rong, Andrew Reilly, Anne Messer
Hum Mol Genet 2015 Aug;
PMID: 26307082 [PubMed - as supplied by publisher]

A Physical Interaction between the Dopamine Transporter and DJ-1 Facilitates Increased Dopamine Reuptake.
Beryl Luk, Mohinuddin Mohammed, Fang Liu, Frank J S Lee
PLoS One 2015 ; 10(8):e0136641
PMID: 26305376 [PubMed - as supplied by publisher]

LRRK2 Facilitates tau Phosphorylation through Strong Interaction with tau and cdk5.
Mary R Shanley, Dillon Hawley, Shirley Leung, Nikhat F Zaidi, Roshni Dave, Kate A Schlosser, Rina Bandopadhyay, Scott A Gerber, Min Liu
Biochemistry 2015 Aug; 54(33):5198-208
PMID: 26268594 [PubMed - as supplied by publisher]

Regulation of mitochondrial morphology and function by stearoylation of TFR1.
Deniz Senyilmaz, Sam Virtue, Xiaojun Xu, Chong Yew Tan, Julian L Griffin, Aubry K Miller, Antonio Vidal-Puig, Aurelio A Teleman
Nature 2015 Jul;
PMID: 26214738 [PubMed - as supplied by publisher]

Clinical and imaging markers in premotor LRRK2 G2019S mutation carriers.
Dolores Vilas, Lourdes Ispierto, Ramiro Álvarez, Claustre Pont-Sunyer, María José Martí, Francesc Valldeoriola, Yaroslau Compta, Oriol de Fabregues, Jorge Hernández-Vara, Víctor Puente, Matilde Calopa, Serge Jaumà, Jaume Campdelacreu, Miquel Aguilar, Pilar Quílez, Pilar Casquero, Francisco Lomeña, José Ríos, Eduardo Tolosa
Parkinsonism Relat Disord 2015 Aug;
PMID: 26306001 [PubMed - as supplied by publisher]

Association analysis of the GRN rs5848 and MAPT rs242557 polymorphisms in Parkinson disease and multiple system atrophy: A large-scale population-based study and meta-analysis.
YongPing Chen, Bei Cao, RuWei Ou, XuePing Chen, Bi Zhao, QianQian Wei, Ying Wu, Hui-Fang Shang
Int J Neurosci 2015 Aug; :1-24
PMID: 26303052 [PubMed - as supplied by publisher]

Overexpression of DJ-1 protects against C2-ceramide-induced neuronal death through activation of the PI3K/AKT pathway and inhibition of autophagy.
Jenny Jaramillo-Gómez, Andrea Niño, Humberto Arboleda, Gonzalo Arboleda
Neurosci Lett 2015 Aug; 603:71-6
PMID: 26222260 [PubMed - as supplied by publisher]

Association between ?-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease.
Joseph J Locascio, Shirley Eberly, Zhixiang Liao, Ganqiang Liu, Ashley N Hoesing, Karen Duong, Ana Trisini-Lipsanopoulos, Kaltra Dhima, Albert Y Hung, Alice W Flaherty, Michael A Schwarzschild, Michael T Hayes, Anne-Marie Wills, U Shivraj Sohur, Nicte I Mejia, Dennis J Selkoe, David Oakes, Ira Shoulson, Xianjun Dong, Ken Marek, Bin Zheng, Adrian Ivinson, Bradley T Hyman, John H Growdon, Lewis R Sudarsky, Michael G Schlossmacher, Bernard Ravina, Clemens R Scherzer
Brain 2015 Sep; 138(Pt 9):2659-71
PMID: 26220939 [PubMed - as supplied by publisher]

Electron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial Bioenergetics.
Levente Szalárdy, Dénes Zádori, Péter Klivényi, József Toldi, László Vécsei
Oxid Med Cell Longev 2015 ; 2015:498401
PMID: 26301042 [PubMed - as supplied by publisher]

Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.
Chrystian J Alves, Rafael Dariolli, Frederico M Jorge, Matheus R Monteiro, Jessica R Maximino, Roberto S Martins, Bryan E Strauss, José E Krieger, Dagoberto Callegaro, Gerson Chadi
Front Cell Neurosci 2015 ; 9:289
PMID: 26300727 [PubMed - as supplied by publisher]

D620N mutation in the VPS35 gene and R1205H mutation in the EIF4G1 gene are uncommon in the Greek population.
Kallirhoe Kalinderi, Sevasti Bostantjopoulou, Zoe Katsarou, Maria Dimikiotou, Liana Fidani
Neurosci Lett 2015 Aug;
PMID: 26300542 [PubMed - as supplied by publisher]

Pharmacological targeting of dopamine D3 receptors: Possible clinical applications of selective agents.
Emilio Merlo Pich, Ginetta Collo
Eur Neuropsychopharmacol 2015 Jul;
PMID: 26298833 [PubMed - as supplied by publisher]

Exon dosage analysis of parkin gene in Chinese sporadic Parkinson's disease.
Ji-Feng Guo, Xiao-Li Dong, Qian Xu, Nan Li, Xin-Xiang Yan, Kun Xia, Bei-Sha Tang
Neurosci Lett 2015 Aug; 604:47-51
PMID: 26240990 [PubMed - as supplied by publisher]

Genetic Identification Is Critical for the Diagnosis of Parkinsonism: A Chinese Pedigree with Early Onset of Parkinsonism.
Yang Yang, Bei-Sha Tang, Ling Weng, Nan Li, Lu Shen, Jian Wang, Chuan-Tao Zuo, Xin-Xiang Yan, Kun Xia, Ji-Feng Guo
PLoS One 2015 ; 10(8):e0136245
PMID: 26295349 [PubMed - as supplied by publisher]

GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease.
Ignacio F Mata, James B Leverenz, Daniel Weintraub, John Q Trojanowski, Alice Chen-Plotkin, Vivianna M Van Deerlin, Beate Ritz, Rebecca Rausch, Stewart A Factor, Cathy Wood-Siverio, Joseph F Quinn, Kathryn A Chung, Amie L Peterson-Hiller, Jennifer G Goldman, Glenn T Stebbins, Bryan Bernard, Alberto J Espay, Fredy J Revilla, Johnna Devoto, Liana S Rosenthal, Ted M Dawson, Marilyn S Albert, Debby Tsuang, Haley Huston, Dora Yearout, Shu-Ching Hu, Brenna A Cholerton, Thomas J Montine, Karen L Edwards, Cyrus P Zabetian
Mov Disord 2015 Aug;
PMID: 26296077 [PubMed - as supplied by publisher]

A Fluorescence Resonance Energy Transfer Assay For Monitoring ?-Synclein Aggregation In A Caenorhabditis elegans Model For Parkinson's Disease.
Archana Nagarajan, Rakesh Bodhicharla, Jody Winter, Charumathi Anbalagan, Kevin Morgan, Mark Searle, Aamir Nazir, Ademola Adenle, April Fineberg, Declan Brady, Kelly Vere, Jo Richens, Paul O'Shea, David Bell, David de-Pomerai
CNS Neurol Disord Drug Targets 2015 Aug;
PMID: 26295817 [PubMed - as supplied by publisher]

Application of polymeric nanoparticles for CNS targeted zinc delivery in vivo.
Resham Chhabra, Barbara Ruozi, Antonietta Vilella, Daniela Belletti, Katharina Mangus, Stefanie Pfaender, Tasnuva Sarowar, Tobias M Boeckers, Michele Zoli, Flavio Forni, Maria Angela Vandelli, Giovanni Tosi, Andreas M Grabrucker
CNS Neurol Disord Drug Targets 2015 Aug;
PMID: 26295815 [PubMed - as supplied by publisher]

An Efficient and Versatile System for Visualization and Genetic Modification of Dopaminergic Neurons in Transgenic Mice.
Karsten Tillack, Helia Aboutalebi, Edgar R Kramer
PLoS One 2015 ; 10(8):e0136203
PMID: 26291828 [PubMed - as supplied by publisher]

Lymphocytes reduce nigrostriatal deficits in the 6-hydroxydopamine mouse model of Parkinson's disease.
Chi Wang Ip, Sandra K Beck, Jens Volkmann
J Neural Transm 2015 Aug;
PMID: 26290125 [PubMed - as supplied by publisher]

Intranasal gene delivery for treating Parkinson's disease: overcoming the blood-brain barrier.
Amirah E-E Aly, Barbara L Waszczak
Expert Opin Drug Deliv 2015 Aug; :1-19
PMID: 26289676 [PubMed - as supplied by publisher]

Propagation of prions causing synucleinopathies in cultured cells.
Amanda L Woerman, Jan Stöhr, Atsushi Aoyagi, Ryan Rampersaud, Zuzana Krejciova, Joel C Watts, Takao Ohyama, Smita Patel, Kartika Widjaja, Abby Oehler, David W Sanders, Marc I Diamond, William W Seeley, Lefkos T Middleton, Steve M Gentleman, Daniel A Mordes, Thomas C Südhof, Kurt Giles, Stanley B Prusiner
Proc Natl Acad Sci U S A 2015 Aug;
PMID: 26286986 [PubMed - as supplied by publisher]

Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains.
Douglas G Walker, Lih-Fen Lue
Alzheimers Res Ther 2015 ; 7(1):56
PMID: 26286145 [PubMed - as supplied by publisher]

Retraction Note to: Genetic polymorphisms in VDR, ESR1 and ESR2 genes may contribute to susceptibility to Parkinson's disease: a meta-analysis.
Zhan Gao, Hong-Juan Fu, Ju-Jun Xue, Zhi-Xuan Wu, Li-Bo Zhao
Mol Biol Rep 2015 Aug;
PMID: 26285929 [PubMed - as supplied by publisher]

VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin.
Bilal R Malik, Vinay K Godena, Alexander J Whitworth
Hum Mol Genet 2015 Aug;
PMID: 26251041 [PubMed - as supplied by publisher]

Exome analysis of a family with Wolff-Parkinson-White syndrome identifies a novel disease locus.
Neil E Bowles, Chuanchau J Jou, Cammon B Arrington, Brett J Kennedy, Aubree Earl, Norisada Matsunami, Lindsay L Meyers, Susan P Etheridge, Elizabeth V Saarel, Steven B Bleyl, H Joseph Yost, Mark Yandell, Mark F Leppert, Martin Tristani-Firouzi, Peter J Gruber,
Am J Med Genet A 2015 Aug;
PMID: 26284702 [PubMed - as supplied by publisher]

Genome-wide variant by serum urate interaction in Parkinson's Disease.
Arash Nazeri, Tina Roostaei, Shokufeh Sadaghiani, M Mallar Chakravarty, Shirley Eberly, Anthony E Lang, Aristotle N Voineskos
Ann Neurol 2015 Aug;
PMID: 26284320 [PubMed - as supplied by publisher]

DJ1 expression downregulates in neuroblastoma cells (SK-N-MC) chronically exposed to HIV-1 and cocaine.
Upal Roy, Venkata S R Atluri, Marisela Agudelo, Adriana Yndart, Zaohua Huang, Madhavan Nair
Front Microbiol 2015 ; 6:749
PMID: 26284039 [PubMed - as supplied by publisher]

Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.
Alessandro Pristerà, Wei Lin, Anna-Kristin Kaufmann, Katherine R Brimblecombe, Sarah Threlfell, Paul D Dodson, Peter J Magill, Cathy Fernandes, Stephanie J Cragg, Siew-Lan Ang
Proc Natl Acad Sci U S A 2015 Aug;
PMID: 26283356 [PubMed - as supplied by publisher]

Retraction Note to: Gene expression profiling analysis of locus coeruleus in idiopathic Parkinson's disease by bioinformatics.
Shuqin Cui, Hanwen Sun, Xiangling Gu, E Lv, Yancong Zhang, Pingxuan Dong, Chunhua Fu, Chao Zhu
Neurol Sci 2015 Aug;
PMID: 26282615 [PubMed - as supplied by publisher]

Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release.
Mattia Volta, Stefano Cataldi, Dayne Beccano-Kelly, Lise Munsie, Igor Tatarnikov, Patrick Chou, Sabrina Bergeron, Emma Mitchell, Roscoe Lim, Jaskaran Khinda, Alejandro Lloret, C Frank Bennett, Carmela Paradiso, Michele Morari, Matthew J Farrer, Austen J Milnerwood
Parkinsonism Relat Disord 2015 Aug;
PMID: 26282470 [PubMed - as supplied by publisher]

Schisandrin B shows neuroprotective effect in 6-OHDA-induced Parkinson's disease via inhibiting the negative modulation of miR-34a on Nrf2 pathway.
Qinghua Ba, Chuanju Cui, Lijun Wen, Shutao Feng, Junchao Zhou, Ke Yang
Biomed Pharmacother 2015 Aug;
PMID: 26282218 [PubMed - as supplied by publisher]

DNAJC13 p.Asn855Ser mutation screening in Parkinson's disease and pathologically confirmed Lewy body disease patients.
O Lorenzo-Betancor, K Ogaki, A I Soto-Ortolaza, C Labbe, R L Walton, A J Strongosky, J A van Gerpen, R J Uitti, P J McLean, W Springer, J Siuda, G Opala, A Krygowska-Wajs, M Barcikowska, K Czyzewski, A McCarthy, T Lynch, A Puschmann, I Rektorova, Y Sanotsky, C Vilariño-Güell, M J Farrer, T J Ferman, B F Boeve, R C Petersen, J E Parisi, N R Graff-Radford, D W Dickson, Z K Wszolek, O A Ross
Eur J Neurol 2015 Sep; 22(9):1323-5
PMID: 26278106 [PubMed - as supplied by publisher]

The placebo effect: From concepts to genes.
B Colagiuri, L A Schenk, M D Kessler, S G Dorsey, L Colloca
Neuroscience 2015 Aug;
PMID: 26272535 [PubMed - as supplied by publisher]

Transient sampling of aggregation-prone conformations causes pathogenic instability of a parkinsonian mutant of DJ-1 at physiological temperature.
Nicole M Milkovic, Jonathan Catazaro, Jiusheng Lin, Steven Halouska, James L Kizziah, Sara Basiaga, Ronald L Cerny, Robert Powers, Mark A Wilson
Protein Sci 2015 Aug;
PMID: 26234586 [PubMed - as supplied by publisher]

C9ORF72 intermediate repeat expansion in patients affected by atypical parkinsonian syndromes or Parkinson's disease complicated by psychosis or dementia in a Sardinian population.
Antonino Cannas, Paolo Solla, Giuseppe Borghero, Gian Luca Floris, Adriano Chio, Marcello Mario Mascia, Nicola Modugno, Antonella Muroni, Gianni Orofino, Francesca Di Stefano, Andrea Calvo, Cristina Moglia, Gabriella Restagno, Mario Meloni, Rita Farris, Daniela Ciaccio, Roberta Puddu, Melisa Iris Vacca, Rosanna Melis, Maria Rita Murru, Stefania Tranquilli, Daniela Corongiu, Marcella Rolesu, Stefania Cuccu, Maria Giovanna Marrosu, Francesco Marrosu
J Neurol 2015 Aug;
PMID: 26275564 [PubMed - as supplied by publisher]

Parkinson's Disease in Saudi Patients: A Genetic Study.
Bashayer R Al-Mubarak, Saeed A Bohlega, Thamer S Alkhairallah, Amna I Magrashi, Maha I AlTurki, Dania S Khalil, Basma S AlAbdulaziz, Hussam Abou Al-Shaar, Abeer E Mustafa, Eman A Alyemni, Bashayer A Alsaffar, Asma I Tahir, Nada A Al Tassan
PLoS One 2015 ; 10(8):e0135950
PMID: 26274610 [PubMed - as supplied by publisher]

Advances in functional neurosurgery for Parkinson's disease.
Leo Verhagen Metman, Konstantin V Slavin
Mov Disord 2015 Aug;
PMID: 26274629 [PubMed - as supplied by publisher]

Aggregation of MBP in chronic demyelination.
Kati Frid, Ofira Einstein, Yael Friedman-Levi, Orli Binyamin, Tamir Ben-Hur, Ruth Gabizon
Ann Clin Transl Neurol 2015 Jul; 2(7):711-21
PMID: 26273684 [PubMed - as supplied by publisher]

The Inflammatory Marker YKL-40 Is Elevated in Cerebrospinal Fluid from Patients with Alzheimer's but Not Parkinson's Disease or Dementia with Lewy Bodies.
Malin Wennström, Yulia Surova, Sara Hall, Christer Nilsson, Lennart Minthon, Oskar Hansson, Henrietta M Nielsen
PLoS One 2015 ; 10(8):e0135458
PMID: 26270969 [PubMed - as supplied by publisher]

Transforming growth factor-?1 acts via T?R-I on microglia to protect against MPP(+)-induced dopaminergic neuronal loss.
Zhan Liu, Hui-Qiao Chen, Yan Huang, Yi-Hua Qiu, Yu-Ping Peng
Brain Behav Immun 2015 Aug;
PMID: 26254549 [PubMed - as supplied by publisher]

The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus.
Eric S Sweet, Bernadette Saunier-Rebori, Zhenyu Yue, Robert D Blitzer
J Neurosci 2015 Aug; 35(32):11190-5
PMID: 26269629 [PubMed - as supplied by publisher]

Gene expression profiling predicts pathways and genes associated with Parkinson's disease.
Shuang Liu, Yong Zhang, Hong Bian, Xiaohong Li
Neurol Sci 2015 Aug;
PMID: 26269422 [PubMed - as supplied by publisher]

Intranasal gene delivery for treating Parkinson's disease: overcoming the blood-brain barrier.
Amirah E-E Aly, Barbara L Waszczak
Expert Opin Drug Deliv 2015 Aug; :1-19
PMID: 26268820 [PubMed - as supplied by publisher]

Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI).
Mike A Nalls, Margaux F Keller, Dena G Hernandez, Lan Chen, David J Stone, Andrew B Singleton,
Mov Disord 2015 Aug;
PMID: 26268663 [PubMed - as supplied by publisher]

Expanding the ubiquitin code through post-translational modification.
Lina Herhaus, Ivan Dikic
EMBO Rep 2015 Aug;
PMID: 26268526 [PubMed - as supplied by publisher]

Variation in PARK10 is not associated with risk and age at onset of Parkinson's disease in large clinical cohorts.
Javier Simón-Sánchez, Peter Heutink, Thomas Gasser,
Neurobiol Aging 2015 Jul;
PMID: 26260214 [PubMed - as supplied by publisher]

Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation.
Koji Yamano, Bruno B Queliconi, Fumika Koyano, Yasushi Saeki, Takatsugu Hirokawa, Keiji Tanaka, Noriyuki Matsuda
J Biol Chem 2015 Aug;
PMID: 26260794 [PubMed - as supplied by publisher]

Genetic Variants in GAPDH Confer Susceptibility to Sporadic Parkinson's Disease in a Chinese Han Population.
Ling Liu, Nian Xiong, Ping Zhang, Chunnuan Chen, Jinsha Huang, Guoxin Zhang, Xiaoyun Xu, Yan Shen, Zhicheng Lin, Tao Wang
PLoS One 2015 ; 10(8):e0135425
PMID: 26258539 [PubMed - as supplied by publisher]

Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson Disease.
David C Bäckström, Magdalena Eriksson Domellöf, Jan Linder, Bob Olsson, Annika Öhrfelt, Miles Trupp, Henrik Zetterberg, Kaj Blennow, Lars Forsgren
JAMA Neurol 2015 Aug;
PMID: 26258692 [PubMed - as supplied by publisher]

A Ubl/ubiquitin switch in the activation of Parkin.
Véronique Sauvé, Asparouh Lilov, Marjan Seirafi, Marta Vranas, Shafqat Rasool, Guennadi Kozlov, Tara Sprules, Jimin Wang, Jean-François Trempe, Kalle Gehring
EMBO J 2015 Aug;
PMID: 26254305 [PubMed - as supplied by publisher]

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Atul Kumar, Jacob D Aguirre, Tara Ec Condos, R Julio Martinez-Torres, Viduth K Chaugule, Rachel Toth, Ramasubramanian Sundaramoorthy, Pascal Mercier, Axel Knebel, Donald E Spratt, Kathryn R Barber, Gary S Shaw, Helen Walden
EMBO J 2015 Aug;
PMID: 26254304 [PubMed - as supplied by publisher]

Analysis and meta-analysis of five polymorphisms of the LINGO1 and LINGO2 genes in Parkinson's disease and multiple system atrophy in a Chinese population.
YongPing Chen, Bei Cao, Jing Yang, QianQian Wei, Ru Wei Ou, Bi Zhao, Wei Song, XiaoYan Guo, HuiFang Shang
J Neurol 2015 Aug;
PMID: 26254004 [PubMed - as supplied by publisher]

G2019S LRRK2 and aging confer susceptibility to proteasome inhibitor-induced neurotoxicity in nigrostriatal dopaminergic system.
Qian Xiao, Suosuo Yang, Weidong Le
J Neural Transm 2015 Aug;
PMID: 26253900 [PubMed - as supplied by publisher]

UDCA exerts beneficial effect on mitochondrial dysfunction in LRRK2G2019S carriers and in vivo.
Heather Mortiboys, Rebecca Furmston, Gunnar Bronstad, Jan Aasly, Chris Elliott, Oliver Bandmann
Neurology 2015 Aug;
PMID: 26253449 [PubMed - as supplied by publisher]

Dysfunction of autophagy as the pathological mechanism of motor neuron disease based on a patient-specific disease model.
Dan-Jing Yang, Liang Zhu, Jie Ren, Rong-Jie Ma, Hongwen Zhu, Jun Xu
Neurosci Bull 2015 Aug; 31(4):445-51
PMID: 26219222 [PubMed - as supplied by publisher]

NEURODEGENERATION. Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A?, tau, and ?-synuclein.
Michel Goedert
Science 2015 Aug; 349(6248):1255555
PMID: 26250687 [PubMed - as supplied by publisher]

RNASeq in C. elegans Following Manganese Exposure.
Nancy L Parmalee, Shahina B Maqbool, Bin Ye, Brent Calder, Aaron B Bowman, Michael Aschner
Curr Protoc Toxicol 2015 ; 65:11.20.1-11.20.17
PMID: 26250396 [PubMed - as supplied by publisher]

Reasoning over genetic variance information in cause-and-effect models of neurodegenerative diseases.
Mufassra Naz, Alpha Tom Kodamullil, Martin Hofmann-Apitius
Brief Bioinform 2015 Aug;
PMID: 26249223 [PubMed - as supplied by publisher]

Polymorphism in the Vesicular Monoamine Transporter 2 Gene Decreases the Risk of Parkinson's Disease in Han Chinese Men.
Xinglong Yang, Pingrong Xu, Quanzhen Zhao, Ran An, Hua Jia, Zhuolin Liu, Yanming Xu
Parkinsons Dis 2015 ; 2015:903164
PMID: 26246935 [PubMed - as supplied by publisher]

Status of the Parkinson's disease gene family expression in non-small-cell lung cancer.
Quan Xing Liu, Hong Zheng, Xu Feng Deng, Dong Zhou, Ji Gang Dai
World J Surg Oncol 2015 ; 13(1):238
PMID: 26245297 [PubMed - as supplied by publisher]

Parkinson's disease associated with a mutation in the PARK2 gene].
Valtteri Kaasinen, Marja Hietala, Mikko Kuoppamäki
Duodecim 2015 ; 131(12):1187-90
PMID: 26245049 [PubMed - as supplied by publisher]

Using iPS Cells toward the Understanding of Parkinson's Disease.
Roger Torrent, Francesca De Angelis Rigotti, Patrizia Dell'Era, Maurizio Memo, Angel Raya, Antonella Consiglio
J Clin Med 2015 ; 4(4):548-66
PMID: 26239346 [PubMed - as supplied by publisher]

Lrrk regulates the dynamic profile of dendritic Golgi outposts through the golgin Lava lamp.
Chin-Hsien Lin, Hsun Li, Yi-Nan Lee, Ying-Ju Cheng, Ruey-Meei Wu, Cheng-Ting Chien
J Cell Biol 2015 Aug; 210(3):471-83
PMID: 26216903 [PubMed - as supplied by publisher]

Protective effects of ginseng on neurological disorders.
Wei-Yi Ong, Tahira Farooqui, Hwee-Ling Koh, Akhlaq A Farooqui, Eng-Ang Ling
Front Aging Neurosci 2015 ; 7:129
PMID: 26236231 [PubMed - as supplied by publisher]

Gene therapy and peripheral nerve repair: a perspective.
Stefan A Hoyng, Fred de Winter, Martijn R Tannemaat, Bas Blits, Martijn J A Malessy, Joost Verhaagen
Front Mol Neurosci 2015 ; 8:32
PMID: 26236188 [PubMed - as supplied by publisher]

LRRK2 A419V variant is a risk factor for Parkinson's disease in Asian population.
Kai Li, Bei-Sha Tang, Zhen-Hua Liu, Ji-Feng Kang, Yuan Zhang, Lu Shen, Nan Li, Xin-Xiang Yan, Kun Xia, Ji-Feng Guo
Neurobiol Aging 2015 Jul;
PMID: 26234753 [PubMed - as supplied by publisher]

Evidence for early and progressive ultrasonic vocalization and oromotor deficits in a PINK1 gene knockout rat model of Parkinson's disease.
Laura M Grant, Cynthia A Kelm-Nelson, Breanna L Hilby, Katherine V Blue, Eunice S Paul Rajamanickam, Joshua D Pultorak, Shelia M Fleming, Michelle R Ciucci
J Neurosci Res 2015 Jul;
PMID: 26234713 [PubMed - as supplied by publisher]

XPR1: a Gene Linked to Primary Familial Brain Calcification Might Help Explain a Spectrum of Neuropsychiatric Disorders.
D A P Moura, J R M Oliveira
J Mol Neurosci 2015 Aug;
PMID: 26231937 [PubMed - as supplied by publisher]

Regenerative Medicine for Parkinson?s Disease.
Takao Yasuhara, Masahiro Kameda, Takashi Agari, Isao Date
Neurol Med Chir (Tokyo) 2015 ; 55 Suppl 1:113-23
PMID: 26236796 [PubMed - as supplied by publisher]

Inducible Lentivirus-Mediated Expression of the Oct4 Gene Affects Multilineage Differentiation of Adult Human Bone Marrow-Derived Mesenchymal Stem Cells.
Qiang Hao, Jia-Qiang An, Fei Hao, Chun Yang, Tao Lu, Ting-Yu Qu, Li-Ru Zhao, Wei-Ming Duan
Cell Reprogram 2015 Jul;
PMID: 26230571 [PubMed - as supplied by publisher]

A Pooling Genome-Wide Association Study Combining a Pathway Analysis for Typical Sporadic Parkinson's Disease in the Han Population of Chinese Mainland.
Yakun Hu, Libing Deng, Jie Zhang, Xin Fang, Puming Mei, Xuebing Cao, Jiari Lin, Yi Wei, Xiong Zhang, Renshi Xu
Mol Neurobiol 2015 Jul;
PMID: 26227905 [PubMed - as supplied by publisher]

Therapeutic advances in multiple system atrophy and progressive supranuclear palsy.
Werner Poewe, Philipp Mahlknecht, Florian Krismer
Mov Disord 2015 Jul;
PMID: 26227071 [PubMed - as supplied by publisher]

Therapeutic advances in Huntington's Disease.
Kathleen M Shannon, Avram Fraint
Mov Disord 2015 Jul;
PMID: 26226924 [PubMed - as supplied by publisher]

Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models.
Pascaline Aimé, Xiaotian Sun, Neela Zareen, Apeksha Rao, Zachary Berman, Laura Volpicelli-Daley, Paulette Bernd, John F Crary, Oren A Levy, Lloyd A Greene
J Neurosci 2015 Jul; 35(30):10731-49
PMID: 26224857 [PubMed - as supplied by publisher]

Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion.
Changhai Tian, Yuju Li, Yunlong Huang, Yongxiang Wang, Dapeng Chen, Jinxu Liu, Xiaobei Deng, Lijun Sun, Kristi Anderson, Xinrui Qi, Yulong Li, R Lee Mosley, Xiangmei Chen, Jian Huang, Jialin C Zheng
Sci Rep 2015 ; 5:12622
PMID: 26224135 [PubMed - as supplied by publisher]

No association of FAM47E rs6812193, SCARB2 rs6825004 and STX1B rs4889603 polymorphisms with Parkinson's disease in a Chinese Han population.
YongPing Chen, XiaoQin Yuan, Bei Cao, QianQian Wei, RuWei Ou, Jing Yang, XuePing Chen, Bi Zhao, Wei Song, Ying Wu, HuiFang Shang
J Neural Transm 2015 Jul;
PMID: 26224037 [PubMed - as supplied by publisher]

ALCAR Exerts Neuroprotective and Pro-Neurogenic Effects by Inhibition of Glial Activation and Oxidative Stress via Activation of the Wnt/?-Catenin Signaling in Parkinsonian Rats.
Sonu Singh, Akanksha Mishra, Shubha Shukla
Mol Neurobiol 2015 Jul;
PMID: 26223802 [PubMed - as supplied by publisher]

Genes associated with Parkinson's disease: regulation of autophagy and beyond.
Alexandra Beilina, Mark R Cookson
J Neurochem 2015 Jul;
PMID: 26223426 [PubMed - as supplied by publisher]

Pharmacophore Model Prediction, 3D-QSAR and Molecular Docking studies on Vinyl Sulfones Targeting Nrf2-Mediated Gene Transcription intended for Anti-Parkinson Drug Design.
Mohd Athar, Mohsin Yousuf Lone, Vijay M Khedkar, Prakash Chandra Jha
J Biomol Struct Dyn 2015 Jul; :1-39
PMID: 26222438 [PubMed - as supplied by publisher]

Efficient expression of Igf-1 from lentiviral vectors protects in vitro but does not mediate behavioral recovery of a Parkinsonian lesion in rats.
Ngoc B Lu-Nguyen, Martin Broadstock, Rafael J Yáñez-Muñoz
Hum Gene Ther 2015 Jul;
PMID: 26222254 [PubMed - as supplied by publisher]

The ubiquitin proteasome system as a potential therapeutic target for treatment of neurodegenerative diseases.
Alena Opattova, Martin Cente, Michal Novak, Peter Filipcik
Gen Physiol Biophys 2015 Jul;
PMID: 26221742 [PubMed - as supplied by publisher]

A new knock-in mouse model of l-DOPA-responsive dystonia.
Samuel J Rose, Xin Y Yu, Ann K Heinzer, Porter Harrast, Xueliang Fan, Robert S Raike, Valerie B Thompson, Jean-Francois Pare, David Weinshenker, Yoland Smith, Hyder A Jinnah, Ellen J Hess
Brain 2015 Jul;
PMID: 26220941 [PubMed - as supplied by publisher]

Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson's Disease: Environmental and Genetic Evidence.
Tomás R Guilarte, Kalynda K Gonzales
Toxicol Sci 2015 Aug; 146(2):204-12
PMID: 26220508 [PubMed - as supplied by publisher]

Generation of Naivetropic Induced Pluripotent Stem Cells from Parkinson's Disease Patients for High Efficiency Genetic Manipulation and Disease Modeling.
Zhixing Hu, Jiali Pu, Houbo Jiang, Ping Zhong, Jingxin Qiu, Feng Li, Xiaomin Wang, Baorong Zhang, Zhen Yan, Jian Feng
Stem Cells Dev 2015 Jul;
PMID: 26218671 [PubMed - as supplied by publisher]

Oxidative stress and Parkinson's disease.
Javier Blesa, Ines Trigo-Damas, Anna Quiroga-Varela, Vernice R Jackson-Lewis
Front Neuroanat 2015 ; 9:91
PMID: 26217195 [PubMed - as supplied by publisher]

Closed-loop stimulation of a delayed neural fields model of parkinsonian STN-GPe network: a theoretical and computational study.
Georgios Is Detorakis, Antoine Chaillet, Stéphane Palfi, Suhan Senova
Front Neurosci 2015 ; 9:237
PMID: 26217171 [PubMed - as supplied by publisher]

Did ?-Synuclein and Glucocerebrosidase Coevolve? Implications for Parkinson's Disease.
James M Gruschus
PLoS One 2015 ; 10(7):e0133863
PMID: 26214314 [PubMed - as supplied by publisher]