Can we predict who is at risk of facing cognitive issues in PD and address them earlier? These are the questions being pursued by Dr. Goldman of the PDF Research Center at Rush University Medical Center.
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Tau protein, beta-amyloid1-42 and clusterin CSF levels in the differential diagnosis of Parkinsonian syndrome with dementia.
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J Neurol Sci 2014 Aug; 343(1-2):120-4
Authors: Hana P?ikrylová Vranová, Eva Hényková, Michaela Kaiserová, Kate?ina Men?íková, Miroslav Va?tík, Jan Mare?, Petr Hlu?tík, Jana Zapletalová, Miroslav Strnad, David Stejskal, Petr Ka?ovský
Parkinson's disease (PD), PD with dementia (PDD) and Lewy body dementia (DLB) are synucleinopathies. PDD and DLB are sometimes considered a transition between PD and Alzheimer dementia (AD). Finding in vivo markers or their combination could help in the differential diagnosis of these neurodegenerative (ND) diseases.
PMID: 24928081 [PubMed - as supplied by publisher]