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Kim and Libbe Erickson, R.N.

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Genetics and PD

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Exon dosage analysis of parkin gene in Chinese sporadic Parkinson's disease.
Ji-Feng Guo, Xiao-Li Dong, Qian Xu, Nan Li, Xin-Xiang Yan, Kun Xia, Bei-Sha Tang
Neurosci Lett 2015 Aug;
PMID: 26240990 [PubMed - as supplied by publisher]

Using iPS Cells toward the Understanding of Parkinson's Disease.
Roger Torrent, Francesca De Angelis Rigotti, Patrizia Dell'Era, Maurizio Memo, Angel Raya, Antonella Consiglio
J Clin Med 2015 ; 4(4):548-66
PMID: 26239346 [PubMed - as supplied by publisher]

Lrrk regulates the dynamic profile of dendritic Golgi outposts through the golgin Lava lamp.
Chin-Hsien Lin, Hsun Li, Yi-Nan Lee, Ying-Ju Cheng, Ruey-Meei Wu, Cheng-Ting Chien
J Cell Biol 2015 Aug; 210(3):471-83
PMID: 26216903 [PubMed - as supplied by publisher]

Protective effects of ginseng on neurological disorders.
Wei-Yi Ong, Tahira Farooqui, Hwee-Ling Koh, Akhlaq A Farooqui, Eng-Ang Ling
Front Aging Neurosci 2015 ; 7:129
PMID: 26236231 [PubMed - as supplied by publisher]

Gene therapy and peripheral nerve repair: a perspective.
Stefan A Hoyng, Fred de Winter, Martijn R Tannemaat, Bas Blits, Martijn J A Malessy, Joost Verhaagen
Front Mol Neurosci 2015 ; 8:32
PMID: 26236188 [PubMed - as supplied by publisher]

LRRK2 A419V variant is a risk factor for Parkinson's disease in Asian population.
Kai Li, Bei-Sha Tang, Zhen-Hua Liu, Ji-Feng Kang, Yuan Zhang, Lu Shen, Nan Li, Xin-Xiang Yan, Kun Xia, Ji-Feng Guo
Neurobiol Aging 2015 Jul;
PMID: 26234753 [PubMed - as supplied by publisher]

Evidence for early and progressive ultrasonic vocalization and oromotor deficits in a PINK1 gene knockout rat model of Parkinson's disease.
Laura M Grant, Cynthia A Kelm-Nelson, Breanna L Hilby, Katherine V Blue, Eunice S Paul Rajamanickam, Joshua D Pultorak, Shelia M Fleming, Michelle R Ciucci
J Neurosci Res 2015 Jul;
PMID: 26234713 [PubMed - as supplied by publisher]

Transient Sampling of Aggregation-prone Conformations Causes Pathogenic Instability of a Parkinsonian Mutant of DJ-1 at Physiological Temperature.
Nicole M Milkovic, Jonathan Catazaro, Jiusheng Lin, Steven Halouska, James L Kizziah, Sara Basiaga, Ronald L Cerny, Robert Powers, Mark A Wilson
Protein Sci 2015 Aug;
PMID: 26234586 [PubMed - as supplied by publisher]

Regulation of mitochondrial morphology and function by stearoylation of TFR1.
Deniz Senyilmaz, Sam Virtue, Xiaojun Xu, Chong Yew Tan, Julian L Griffin, Aubry K Miller, Antonio Vidal-Puig, Aurelio A Teleman
Nature 2015 Jul;
PMID: 26214738 [PubMed - as supplied by publisher]

Investigating the role of Sirt1-modulated oxidative stress in relation to benign paroxysmal positional vertigo and Parkinson's disease.
Kun-Ling Tsai, Yuan-Yang Cheng, Hsin-Bang Leu, Yi-Yen Lee, Tzeng-Ji Chen, Ding-Hao Liu, Chung-Lan Kao
Neurobiol Aging 2015 Sep; 36(9):2607-16
PMID: 26130063 [PubMed - as supplied by publisher]

Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study.
Rachel Grashow, David Sparrow, Howard Hu, Marc G Weisskopf
Neurotoxicology 2015 Jul; 49:158-64
PMID: 26121922 [PubMed - as supplied by publisher]

Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice.
Vera L Bonilha, Brent A Bell, Mary E Rayborn, Xiaoping Yang, Charlie Kaul, Gregory H Grossman, Ivy S Samuels, Joe G Hollyfield, Chengsong Xie, Huaibin Cai, Karen G Shadrach
Exp Eye Res 2015 Jul; 139:22-36
PMID: 26215528 [PubMed - as supplied by publisher]

An early axonopathy in a hLRRK2(R1441G) transgenic model of Parkinson disease.
Patricia Tagliaferro, Tatyana Kareva, Tinmarla F Oo, Olga Yarygina, Nikolai Kholodilov, Robert E Burke
Neurobiol Dis 2015 Jul; 82:359-371
PMID: 26192625 [PubMed - as supplied by publisher]

NRSF is an essential mediator for the neuroprotection of trichostatin A in the MPTP mouse model of Parkinson's disease.
Haiyun Suo, Pan Wang, Jiabin Tong, Lei Cai, Jie Liu, Dongping Huang, Li Huang, Zishan Wang, Yufang Huang, Jing Xu, Yuanyuan Ma, Mei Yu, Jian Fei, Fang Huang
Neuropharmacology 2015 Jul; 99:67-78
PMID: 26188143 [PubMed - as supplied by publisher]

XPR1: a Gene Linked to Primary Familial Brain Calcification Might Help Explain a Spectrum of Neuropsychiatric Disorders.
D A P Moura, J R M Oliveira
J Mol Neurosci 2015 Aug;
PMID: 26231937 [PubMed - as supplied by publisher]

Loss of glutamic acid decarboxylase (Gad67) in striatal neurons expressing the Drdr1a dopamine receptor prevents l-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned mice.
K Zhang, C Chammas, J-J Soghomonian
Neuroscience 2015 Jul; 303:586-594
PMID: 26188284 [PubMed - as supplied by publisher]

GDNF-secreting mesenchymal stem cells provide localized neuroprotection in an inflammation-driven rat model of Parkinson's disease.
D B Hoban, L Howard, E Dowd
Neuroscience 2015 Jul; 303:402-411
PMID: 26166730 [PubMed - as supplied by publisher]

Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway.
X S Zhang, S Ha, X L Wang, Y L Shi, S S Duan, Z A Li
Neuroscience 2015 Jun; 303:489-502
PMID: 26116522 [PubMed - as supplied by publisher]

Regenerative Medicine for Parkinson?s Disease.
Takao Yasuhara, Masahiro Kameda, Takashi Agari, Isao Date
Neurol Med Chir (Tokyo) 2015 ; 55 Suppl 1:113-23
PMID: 26236796 [PubMed - as supplied by publisher]

Molecular Cloning, Epigenetic Regulation and Functional Characterization of Prkd1 Gene Promoter in Dopaminergic Cell Culture Models of Parkinson's Disease.
Muhammet Ay, Huajun Jin, Dilshan S Harischandra, Arunkumar Asaithambi, Arthi Kanthasamy, Vellareddy Anantharam, Anumantha G Kanthasamy
J Neurochem 2015 Jul;
PMID: 26230914 [PubMed - as supplied by publisher]

Inducible Lentivirus-Mediated Expression of the Oct4 Gene Affects Multilineage Differentiation of Adult Human Bone Marrow-Derived Mesenchymal Stem Cells.
Qiang Hao, Jia-Qiang An, Fei Hao, Chun Yang, Tao Lu, Ting-Yu Qu, Li-Ru Zhao, Wei-Ming Duan
Cell Reprogram 2015 Jul;
PMID: 26230571 [PubMed - as supplied by publisher]

A Pooling Genome-Wide Association Study Combining a Pathway Analysis for Typical Sporadic Parkinson's Disease in the Han Population of Chinese Mainland.
Yakun Hu, Libing Deng, Jie Zhang, Xin Fang, Puming Mei, Xuebing Cao, Jiari Lin, Yi Wei, Xiong Zhang, Renshi Xu
Mol Neurobiol 2015 Jul;
PMID: 26227905 [PubMed - as supplied by publisher]

Therapeutic advances in multiple system atrophy and progressive supranuclear palsy.
Werner Poewe, Philipp Mahlknecht, Florian Krismer
Mov Disord 2015 Jul;
PMID: 26227071 [PubMed - as supplied by publisher]

Therapeutic advances in Huntington's Disease.
Kathleen M Shannon, Avram Fraint
Mov Disord 2015 Jul;
PMID: 26226924 [PubMed - as supplied by publisher]

Nrf2-ARE signals mediated the anti-oxidative action of electroacupuncture in an MPTP mouse model of Parkinson's disease.
E Lv, J Deng, Y Yu, Y Wang, X Gong, J Jia, X Wang
Free Radic Res 2015 Jul; :1-12
PMID: 26118717 [PubMed - as supplied by publisher]

Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models.
Pascaline Aimé, Xiaotian Sun, Neela Zareen, Apeksha Rao, Zachary Berman, Laura Volpicelli-Daley, Paulette Bernd, John F Crary, Oren A Levy, Lloyd A Greene
J Neurosci 2015 Jul; 35(30):10731-49
PMID: 26224857 [PubMed - as supplied by publisher]

Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion.
Changhai Tian, Yuju Li, Yunlong Huang, Yongxiang Wang, Dapeng Chen, Jinxu Liu, Xiaobei Deng, Lijun Sun, Kristi Anderson, Xinrui Qi, Yulong Li, R Lee Mosley, Xiangmei Chen, Jian Huang, Jialin C Zheng
Sci Rep 2015 ; 5:12622
PMID: 26224135 [PubMed - as supplied by publisher]

No association of FAM47E rs6812193, SCARB2 rs6825004 and STX1B rs4889603 polymorphisms with Parkinson's disease in a Chinese Han population.
YongPing Chen, XiaoQin Yuan, Bei Cao, QianQian Wei, RuWei Ou, Jing Yang, XuePing Chen, Bi Zhao, Wei Song, Ying Wu, HuiFang Shang
J Neural Transm 2015 Jul;
PMID: 26224037 [PubMed - as supplied by publisher]

ALCAR Exerts Neuroprotective and Pro-Neurogenic Effects by Inhibition of Glial Activation and Oxidative Stress via Activation of the Wnt/?-Catenin Signaling in Parkinsonian Rats.
Sonu Singh, Akanksha Mishra, Shubha Shukla
Mol Neurobiol 2015 Jul;
PMID: 26223802 [PubMed - as supplied by publisher]

Genes associated with Parkinson's disease: regulation of autophagy and beyond.
Alexandra Beilina, Mark R Cookson
J Neurochem 2015 Jul;
PMID: 26223426 [PubMed - as supplied by publisher]

Heterozygote carriers for CNVs in PARK2 are at increased risk of Parkinson's disease.
Johanna Huttenlocher, Hreinn Stefansson, Stacy Steinberg, Hafdis T Helgadottir, Sigurlaug Sveinbjörnsdóttir, Olaf Riess, Peter Bauer, Kari Stefansson
Hum Mol Genet 2015 Jul;
PMID: 26188007 [PubMed - as supplied by publisher]

Pharmacophore Model Prediction, 3D-QSAR and Molecular Docking studies on Vinyl Sulfones Targeting Nrf2-Mediated Gene Transcription intended for Anti-Parkinson Drug Design.
Mohd Athar, Mohsin Yousuf Lone, Vijay M Khedkar, Prakash Chandra Jha
J Biomol Struct Dyn 2015 Jul; :1-39
PMID: 26222438 [PubMed - as supplied by publisher]

Overexpression of DJ-1 protects against C2-ceramide-induced neuronal death through activation of the PI3K/AKT pathway and inhibition of autophagy.
Jenny Jaramillo-Gómez, Andrea Niño, Humberto Arboleda, Gonzalo Arboleda
Neurosci Lett 2015 Jul;
PMID: 26222260 [PubMed - as supplied by publisher]

Efficient expression of Igf-1 from lentiviral vectors protects in vitro but does not mediate behavioral recovery of a Parkinsonian lesion in rats.
Ngoc B Lu-Nguyen, Martin Broadstock, Rafael J Yáñez-Muñoz
Hum Gene Ther 2015 Jul;
PMID: 26222254 [PubMed - as supplied by publisher]

The ubiquitin proteasome system as a potential therapeutic target for treatment of neurodegenerative diseases.
Alena Opattova, Martin Cente, Michal Novak, Peter Filipcik
Gen Physiol Biophys 2015 Jul;
PMID: 26221742 [PubMed - as supplied by publisher]

A new knock-in mouse model of l-DOPA-responsive dystonia.
Samuel J Rose, Xin Y Yu, Ann K Heinzer, Porter Harrast, Xueliang Fan, Robert S Raike, Valerie B Thompson, Jean-Francois Pare, David Weinshenker, Yoland Smith, Hyder A Jinnah, Ellen J Hess
Brain 2015 Jul;
PMID: 26220941 [PubMed - as supplied by publisher]

Association between ?-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease.
Joseph J Locascio, Shirley Eberly, Zhixiang Liao, Ganqiang Liu, Ashley N Hoesing, Karen Duong, Ana Trisini-Lipsanopoulos, Kaltra Dhima, Albert Y Hung, Alice W Flaherty, Michael A Schwarzschild, Michael T Hayes, Anne-Marie Wills, U Shivraj Sohur, Nicte I Mejia, Dennis J Selkoe, David Oakes, Ira Shoulson, Xianjun Dong, Ken Marek, Bin Zheng, Adrian Ivinson, Bradley T Hyman, John H Growdon, Lewis R Sudarsky, Michael G Schlossmacher, Bernard Ravina, Clemens R Scherzer
Brain 2015 Jul;
PMID: 26220939 [PubMed - as supplied by publisher]

Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson's Disease: Environmental and Genetic Evidence.
Tomás R Guilarte, Kalynda K Gonzales
Toxicol Sci 2015 Aug; 146(2):204-12
PMID: 26220508 [PubMed - as supplied by publisher]

Dysfunction of autophagy as the pathological mechanism of motor neuron disease based on a patient-specific disease model.
DanJing Yang, Liang Zhu, Jie Ren, RongJie Ma, Hongwen Zhu, Jun Xu
Neurosci Bull 2015 Jul;
PMID: 26219222 [PubMed - as supplied by publisher]

Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies.
Mathieu Bourdenx, Nikolaos Stavros Koulakiotis, Despina Sanoudou, Erwan Bezard, Benjamin Dehay, Anthony Tsarbopoulos
Prog Neurobiol 2015 Jul;
PMID: 26209472 [PubMed - as supplied by publisher]

Generation of Naivetropic Induced Pluripotent Stem Cells from Parkinson's Disease Patients for High Efficiency Genetic Manipulation and Disease Modeling.
Zhixing Hu, Jiali Pu, Houbo Jiang, Ping Zhong, Jingxin Qiu, Feng Li, Xiaomin Wang, Baorong Zhang, Zhen Yan, Jian Feng
Stem Cells Dev 2015 Jul;
PMID: 26218671 [PubMed - as supplied by publisher]

Oxidative stress and Parkinson's disease.
Javier Blesa, Ines Trigo-Damas, Anna Quiroga-Varela, Vernice R Jackson-Lewis
Front Neuroanat 2015 ; 9:91
PMID: 26217195 [PubMed - as supplied by publisher]

Closed-loop stimulation of a delayed neural fields model of parkinsonian STN-GPe network: a theoretical and computational study.
Georgios Is Detorakis, Antoine Chaillet, Stéphane Palfi, Suhan Senova
Front Neurosci 2015 ; 9:237
PMID: 26217171 [PubMed - as supplied by publisher]

Did ?-Synuclein and Glucocerebrosidase Coevolve? Implications for Parkinson's Disease.
James M Gruschus
PLoS One 2015 ; 10(7):e0133863
PMID: 26214314 [PubMed - as supplied by publisher]

Novel LRRK2 mutations in Parkinsonism.
Joanne Trinh, Ilaria Guella, Marna McKenzie, Emil K Gustavsson, Chelsea Szu-Tu, Maria Skaalum Petersen, Alex Rajput, Ali H Rajput, Martin McKeown, Beom S Jeon, Jan O Aasly, Soraya Bardien, Matthew J Farrer
Parkinsonism Relat Disord 2015 Jul;
PMID: 26213354 [PubMed - as supplied by publisher]

RIT2 rs12456492 polymorphism and the risk of Parkinson's disease: A meta-analysis.
Xiaona Zhang, Mengyue Niu, Hong Li, Anmu Xie
Neurosci Lett 2015 Jul; 602:167-171
PMID: 26188085 [PubMed - as supplied by publisher]

Enrichment of Minor Alleles of Common SNPs and Improved Risk Prediction for Parkinson's Disease.
Zuobin Zhu, Dejian Yuan, Denghui Luo, Xitong Lu, Shi Huang
PLoS One 2015 ; 10(7):e0133421
PMID: 26207627 [PubMed - as supplied by publisher]

Disease-modifying strategies for Parkinson's disease.
Lorraine V Kalia, Suneil K Kalia, Anthony E Lang
Mov Disord 2015 Jul;
PMID: 26208210 [PubMed - as supplied by publisher]

A historical overview of protein kinases and their targeted small molecule inhibitors.
Robert Roskoski
Pharmacol Res 2015 Jul;
PMID: 26207888 [PubMed - as supplied by publisher]

Genetic perspective on the role of the Autophagy-Lysosome Pathway in Parkinson disease.
Ziv Gan-Or, Patrick A Dion, Guy A Rouleau
Autophagy 2015 Jul; :0
PMID: 26207393 [PubMed - as supplied by publisher]

Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by ?-synuclein overexpression.
Mathieu Bourdenx, Sandra Dovero, Michel Engeln, Simone Bido, Matthieu F Bastide, Nathalie Dutheil, Isabel Vollenweider, Laetitia Baud, Camille Piron, Virginie Grouthier, Thomas Boraud, Grégory Porras, Qin Li, Veerle Baekelandt, Dieter Scheller, Anne Michel, Pierre-Olivier Fernagut, François Georges, Grégoire Courtine, Erwan Bezard, Benjamin Dehay
Acta Neuropathol Commun 2015 ; 3(1):46
PMID: 26205255 [PubMed - as supplied by publisher]

CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.
Fathia Djelti, Jerome Braudeau, Eloise Hudry, Marc Dhenain, Jennifer Varin, Ivan Bièche, Catherine Marquer, Farah Chali, Sophie Ayciriex, Nicolas Auzeil, Sandro Alves, Dominique Langui, Marie-Claude Potier, Olivier Laprevote, Michel Vidaud, Charles Duyckaerts, Richard Miles, Patrick Aubourg, Nathalie Cartier
Brain 2015 Aug; 138(Pt 8):2383-98
PMID: 26141492 [PubMed - as supplied by publisher]

SNCA rs3822086 C>T Polymorphism Increases the Susceptibility to Parkinson's Disease in a Chinese Han Population.
Chong-Dong Jian, Jian-Min Huang, Lan-Qing Meng, Xue-Bin Li, Rui-Ya Huang, Sheng-Liang Shi, Yuan Wu, Chao Qin, Jin Chen, Yan-Mei Zhang, Shuang Wang, Yin-Ling Feng, Sheng-Nian Zhou
Genet Test Mol Biomarkers 2015 Jul;
PMID: 26203864 [PubMed - as supplied by publisher]

Mutations in presenilin 2 and its implications in Alzheimer's disease and other dementia-associated disorders.
Yan Cai, Seong Soo A An, SangYun Kim
Clin Interv Aging 2015 ; 10:1163-72
PMID: 26203236 [PubMed - as supplied by publisher]

VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for ?-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease.
Fu-Lei Tang, Joanna R Erion, Yun Tian, Wei Liu, Dong-Min Yin, Jian Ye, Baisha Tang, Lin Mei, Wen-Cheng Xiong
J Neurosci 2015 Jul; 35(29):10613-28
PMID: 26203154 [PubMed - as supplied by publisher]

The research progress of genes associated with Parkinson's disease].
Ming Jiang, Chun-li Duan, Hui Yang
Sheng Li Ke Xue Jin Zhan 2015 Apr; 46(2):133-6
PMID: 26201114 [PubMed - as supplied by publisher]

Neurodegenerative changes in the brainstem and olfactory bulb in people older than 50 years old: a descriptive study.
Francine Hehn de Oliveira, Edson Rodrigues Neto, Mariana Kumaira Fonseca, André Silvestre Reitz da Costa, Marcio Aloisio Bezerra Cavalcanti Rockenbach, Renata Dos Santos Padilha, Liana Lisboa Fernandez, Arlete Hilbig
Arq Neuropsiquiatr 2015 Jul; 73(7):569-77
PMID: 26200050 [PubMed - as supplied by publisher]

Neurotensin-polyplex-mediated brain-derived neurotrophic factor gene delivery into nigral dopamine neurons prevents nigrostriatal degeneration in a rat model of early Parkinson's disease.
Nancy G Hernandez-Chan, Michael J Bannon, Carlos E Orozco-Barrios, Lourdes Escobedo, Sergio Zamudio, Fidel De la Cruz, Jose L Gongora-Alfaro, Juan Armendáriz-Borunda, David Reyes-Corona, Armando J Espadas-Alvarez, Yazmin M Flores-Martínez, Jose Ayala-Davila, Maria E Hernandez-Gutierrez, Lenin Pavón, Refugio García-Villegas, Rasajna Nadella, Daniel Martinez-Fong
J Biomed Sci 2015 ; 22(1):59
PMID: 26198255 [PubMed - as supplied by publisher]

A lipid switch unlocks Parkinson's disease-associated ATP13A2.
Tine Holemans, Danny Mollerup Sørensen, Sarah van Veen, Shaun Martin, Diane Hermans, Gerdi Christine Kemmer, Chris Van den Haute, Veerle Baekelandt, Thomas Günther Pomorski, Patrizia Agostinis, Frank Wuytack, Michael Palmgren, Jan Eggermont, Peter Vangheluwe
Proc Natl Acad Sci U S A 2015 Jul; 112(29):9040-5
PMID: 26134396 [PubMed - as supplied by publisher]

Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014.
Michael W Weiner, Dallas P Veitch, Paul S Aisen, Laurel A Beckett, Nigel J Cairns, Jesse Cedarbaum, Michael C Donohue, Robert C Green, Danielle Harvey, Clifford R Jack, William Jagust, John C Morris, Ronald C Petersen, Andrew J Saykin, Leslie Shaw, Paul M Thompson, Arthur W Toga, John Q Trojanowski,
Alzheimers Dement 2015 Jul; 11(7):865-84
PMID: 26194320 [PubMed - as supplied by publisher]

The Alzheimer's Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans.
Ju-Hee Kang, Magdalena Korecka, Michal J Figurski, Jon B Toledo, Kaj Blennow, Henrik Zetterberg, Teresa Waligorska, Magdalena Brylska, Leona Fields, Nirali Shah, Holly Soares, Robert A Dean, Hugo Vanderstichele, Ronald C Petersen, Paul S Aisen, Andrew J Saykin, Michael W Weiner, John Q Trojanowski, Leslie M Shaw,
Alzheimers Dement 2015 Jul; 11(7):772-91
PMID: 26194312 [PubMed - as supplied by publisher]

The Endocrine Dyscrasia that Accompanies Menopause and Andropause Induces Aberrant Cell Cycle Signaling that Triggers Re-entry of Post-mitotic Neurons into the Cell Cycle, Neurodysfunction, Neurodegeneration and Cognitive Disease.
Craig S Atwood, Richard L Bowen
Horm Behav 2015 Jul;
PMID: 26188949 [PubMed - as supplied by publisher]

Role of long purine stretches in controlling the expression of genes associated with neurological disorders.
Himanshu Narayan Singh, Moganty R Rajeswari
Gene 2015 Jul;
PMID: 26149656 [PubMed - as supplied by publisher]

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress.
Alicia M Pickrell, Chiu-Hui Huang, Scott R Kennedy, Alban Ordureau, Dionisia P Sideris, Jake G Hoekstra, J Wade Harper, Richard J Youle
Neuron 2015 Jul; 87(2):371-81
PMID: 26182419 [PubMed - as supplied by publisher]

Prioritization of candidate disease genes by combining topological similarity and semantic similarity.
Bin Liu, Min Jin, Pan Zeng
J Biomed Inform 2015 Jul;
PMID: 26173039 [PubMed - as supplied by publisher]

Early Neurodegeneration in the Brain of a Child Without Functional PKR-like Endoplasmic Reticulum Kinase.
Julius Bruch, Carolin Kurz, Alexandre Vasiljevic, Marc Nicolino, Thomas Arzberger, Günter U Höglinger
J Neuropathol Exp Neurol 2015 Aug; 74(8):850-7
PMID: 26172286 [PubMed - as supplied by publisher]

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.
Guoxiang Liu, Carmelo Sgobio, Xinglong Gu, Lixin Sun, Xian Lin, Jia Yu, Loukia Parisiadou, Chengsong Xie, Namratha Sastry, Jinhui Ding, Kelly M Lohr, Gary W Miller, Yolanda Mateo, David M Lovinger, Huaibin Cai
Hum Mol Genet 2015 Jun;
PMID: 26123485 [PubMed - as supplied by publisher]

Genetic determinants of swallowing impairments among community dwelling older population.
Alicja Raginis-Zborowska, Krisztina Mekli, Antony Payton, William Ollier, Shaheen Hamdy, Neil Pendleton
Exp Gerontol 2015 Jun; 69:196-201
PMID: 26116289 [PubMed - as supplied by publisher]

Colonic bacterial composition in Parkinson's disease.
Ali Keshavarzian, Stefan J Green, Phillip A Engen, Robin M Voigt, Ankur Naqib, Christopher B Forsyth, Ece Mutlu, Kathleen M Shannon
Mov Disord 2015 Jul;
PMID: 26179554 [PubMed - as supplied by publisher]

Genetic Aspects of Huntington's Disease in Latin America. A Systematic Review.
Raphael Machado de Castilhos, Marina Coutinho Augustin, Jose Augusto Dos Santos, C Perandones, Maria Luiza Saraiva-Pereira, Laura Bannach Jardim,
Clin Genet 2015 Jul;
PMID: 26178794 [PubMed - as supplied by publisher]

Sleep Disorders in Parkinsonian and Nonparkinsonian LRRK2 Mutation Carriers.
Claustre Pont-Sunyer, Alex Iranzo, Carles Gaig, Ana Fernández-Arcos, Dolores Vilas, Francesc Valldeoriola, Yaroslau Compta, Ruben Fernández-Santiago, Manel Fernández, Angels Bayés, Matilde Calopa, Pilar Casquero, Oriol de Fàbregues, Serge Jaumà, Victor Puente, Manel Salamero, Maria José Martí, Joan Santamaría, Eduard Tolosa
PLoS One 2015 ; 10(7):e0132368
PMID: 26177462 [PubMed - as supplied by publisher]

Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease.
Chun-Hyung Kim, Baek-Soo Han, Jisook Moon, Deog-Joong Kim, Joon Shin, Sreekanth Rajan, Quoc Toan Nguyen, Mijin Sohn, Won-Gon Kim, Minjoon Han, Inhye Jeong, Kyoung-Shim Kim, Eun-Hye Lee, Yupeng Tu, Jacqueline L Naffin-Olivos, Chang-Hwan Park, Dagmar Ringe, Ho Sup Yoon, Gregory A Petsko, Kwang-Soo Kim
Proc Natl Acad Sci U S A 2015 Jul; 112(28):8756-61
PMID: 26124091 [PubMed - as supplied by publisher]

Prospects of Neurotrophic Factors for Parkinson's Disease: Comparison of Protein and Gene Therapy.
Andrii Domanskyi, Mart Saarma, Mikko Airavaara
Hum Gene Ther 2015 Jul;
PMID: 26176331 [PubMed - as supplied by publisher]

L-dopa increases ?-synuclein DNA methylation in Parkinson's disease patients in vivo and in vitro.
Ina Schmitt, Oliver Kaut, Hassan Khazneh, Laura deBoni, Ashar Ahmad, Daniela Berg, Christine Klein, Holger Fröhlich, Ullrich Wüllner
Mov Disord 2015 Jul;
PMID: 26173746 [PubMed - as supplied by publisher]

The contribution of Niemann-Pick SMPD1 mutations to Parkinson disease in Ashkenazi Jews.
E Dagan, I Schlesinger, M Ayoub, A Mory, M Nassar, A Kurolap, J Peretz-Aharon, R Gershoni-Baruch
Parkinsonism Relat Disord 2015 Jun;
PMID: 26169695 [PubMed - as supplied by publisher]

Toward therapeutic targets for SCA3: Insight into the role of Machado-Joseph disease protein ataxin-3 in misfolded proteins clearance.
Xiaoling Li, Hongmei Liu, Paula L Fischhaber, Tie-Shan Tang
Prog Neurobiol 2015 Jun;
PMID: 26123252 [PubMed - as supplied by publisher]

Genetic analysis of the RAB39B gene in Chinese Han patients with Parkinson's disease.
Lamei Yuan, Xiong Deng, Zhi Song, Zhijian Yang, Bin Ni, Yong Chen, Hao Deng
Neurobiol Aging 2015 Jun;
PMID: 26163985 [PubMed - as supplied by publisher]

(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation.
Fabienne C Fiesel, Maya Ando, Roman Hudec, Anneliese R Hill, Monica Castanedes-Casey, Thomas R Caulfield, Elisabeth L Moussaud-Lamodière, Jeannette N Stankowski, Peter O Bauer, Oswaldo Lorenzo-Betancor, Isidre Ferrer, José M Arbelo, Joanna Siuda, Li Chen, Valina L Dawson, Ted M Dawson, Zbigniew K Wszolek, Owen A Ross, Dennis W Dickson, Wolfdieter Springer
EMBO Rep 2015 Jul;
PMID: 26162776 [PubMed - as supplied by publisher]

Parkin Is Dispensable for Mitochondrial Function, but Its Ubiquitin Ligase Activity Is Critical for Macroautophagy and Neurotransmitters: Therapeutic Potential beyond Parkinson's Disease.
Charbel E-H Moussa
Neurodegener Dis 2015 Jul;
PMID: 26160424 [PubMed - as supplied by publisher]

Low alpha-synuclein levels in the blood are associated with insulin resistance.
Gerardo Rodriguez-Araujo, Hironori Nakagami, Yoichi Takami, Tomohiro Katsuya, Hiroshi Akasaka, Shigeyuki Saitoh, Kazuaki Shimamoto, Ryuichi Morishita, Hiromi Rakugi, Yasufumi Kaneda
Sci Rep 2015 ; 5:12081
PMID: 26159928 [PubMed - as supplied by publisher]

Mutations in LRRK2 potentiate age-related impairment of autophagic flux.
Shamol Saha, Peter E A Ash, Vivek Gowda, Liqun Liu, Orian Shirihai, Benjamin Wolozin
Mol Neurodegener 2015 ; 10(1):26
PMID: 26159606 [PubMed - as supplied by publisher]

Effect of PSEN1 mutations on MAPT methylation in early-onset Alzheimer's disease.
K G Coupland, W S Kim, G M Halliday, M Hallupp, C Dobson-Stone, Jbj Kwok
Curr Alzheimer Res 2015 Jul;
PMID: 26159201 [PubMed - as supplied by publisher]

A Probable Korean Case of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.
Kyum-Yil Kwon, Kuhl Huh, Baik-Lin Eun, Han-Wook Yoo, Eric-Jan Kamsteeg, Hans Scheffer, Seong-Beom Koh
Can J Neurol Sci 2015 Jul; 42(4):271-3
PMID: 26153042 [PubMed - as supplied by publisher]

The contribution of GIGYF2 to Parkinson's disease: a meta-analysis.
Yuan Zhang, Qi-Ying Sun, Ren-He Yu, Ji-Feng Guo, Bei-Sha Tang, Xin-Xiang Yan
Neurol Sci 2015 Jul;
PMID: 26152800 [PubMed - as supplied by publisher]

A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast.
Søs G Mathiassen, Ida B Larsen, Esben G Poulsen, Christian T Madsen, Elena Papaleo, Kresten Lindorff-Larsen, Birthe B Kragelund, Michael L Nielsen, Franziska Kriegenburg, Rasmus Hartmann-Petersen
J Biol Chem 2015 Jul;
PMID: 26152728 [PubMed - as supplied by publisher]

Mutational analysis of SYNJ1 gene (PARK20) in Parkinson's disease in a Taiwanese population.
Kai-Hsiang Chen, Ruey-Meei Wu, Hang-I Lin, Chun-Hwei Tai, Chin-Hsien Lin
Neurobiol Aging 2015 Jun;
PMID: 26149920 [PubMed - as supplied by publisher]

Protracted late infantile ceroid lipofuscinosis due to TPP1 mutations: Clinical, molecular and biochemical characterization in three sibs.
Raffaella Di Giacopo, Luciano Cianetti, Viviana Caputo, Ilaria La Torraca, Fiorella Piemonte, Andrea Ciolfi, Simona Petrucci, Claudio Carta, Paolo Mariotti, Vincenzo Leuzzi, Enza Maria Valente, Adele D'Amico, Annarita Bentivoglio, Enrico Bertini, Marco Tartaglia, Giuseppe Zampino
J Neurol Sci 2015 May;
PMID: 26143525 [PubMed - as supplied by publisher]

Possible Mechanisms Underlying the Therapeutic Effects of Transcranial Magnetic Stimulation.
Alexander V Chervyakov, Andrey Yu Chernyavsky, Dmitry O Sinitsyn, Michael A Piradov
Front Hum Neurosci 2015 ; 9:303
PMID: 26136672 [PubMed - as supplied by publisher]

GIGYF2 mutation in late-onset Parkinson's disease with cognitive impairment.
Javier Ruiz-Martinez, Catharine E Krebs, Vladimir Makarov, Ana Gorostidi, Jose Félix Martí-Massó, Coro Paisán-Ruiz
J Hum Genet 2015 Jul;
PMID: 26134514 [PubMed - as supplied by publisher]

Cerebrospinal fluid tau and amyloid-?1-42 in patients with dementia.
Tobias Skillbäck, Bahman Y Farahmand, Christoffer Rosén, Niklas Mattsson, Katarina Nägga, Lena Kilander, Dorota Religa, Anders Wimo, Bengt Winblad, Jonathan M Schott, Kaj Blennow, Maria Eriksdotter, Henrik Zetterberg
Brain 2015 Jun;
PMID: 26133663 [PubMed - as supplied by publisher]

Identification of Candidate Adherent-Invasive E. coli Signature Transcripts by Genomic/Transcriptomic Analysis.
Yuanhao Zhang, Leahana Rowehl, Julia M Krumsiek, Erika P Orner, Nurmohammad Shaikh, Phillip I Tarr, Erica Sodergren, George M Weinstock, Edgar C Boedeker, Xuejian Xiong, John Parkinson, Daniel N Frank, Ellen Li, Grace Gathungu
PLoS One 2015 ; 10(6):e0130902
PMID: 26125937 [PubMed - as supplied by publisher]

Potential hippocampal genes and pathways involved in Alzheimer's disease: a bioinformatic analysis.
L Zhang, X Q Guo, J F Chu, X Zhang, Z R Yan, Y Z Li
Genet Mol Res 2015 ; 14(2):7218-32
PMID: 26125932 [PubMed - as supplied by publisher]

Association of CHRNA4 gene rs1044396 and rs1044397 polymorphisms with Parkinson's disease symptoms and smoking.
L M Zhang, X P Zhang, Y Q Chen, W Ye
Genet Mol Res 2015 ; 14(2):5112-22
PMID: 26125703 [PubMed - as supplied by publisher]

Gene-based vaccines and immunotherapeutic strategies against neurodegenerative diseases: Potential utility and limitations.
Jeremy J Kudrna, Kenneth E Ugen
Hum Vaccin Immunother 2015 Jun; :0
PMID: 26125436 [PubMed - as supplied by publisher]

Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia.
Simone Bido, Nicola Solari, Marzia Indrigo, Angela D'Antoni, Riccardo Brambilla, Michele Morari, Stefania Fasano
Ann Clin Transl Neurol 2015 Jun; 2(6):662-78
PMID: 26125041 [PubMed - as supplied by publisher]

Physiologically relevant factors influence tau phosphorylation by leucine-rich repeat kinase 2.
Matthew Hamm, Rachel Bailey, Gerry Shaw, Shu-Hui Yen, Jada Lewis, Benoit I Giasson
J Neurosci Res 2015 Jun;
PMID: 26123245 [PubMed - as supplied by publisher]

Gene therapy for neurodegenerative diseases.
Deirdre M O'Connor, Nicholas M Boulis
Trends Mol Med 2015 Jun;
PMID: 26122838 [PubMed - as supplied by publisher]

Mitochondrial dysfunction and Parkinson disease: a Parkin-AMPK alliance in neuroprotection.
Liting Hang, John Thundyil, Kah-Leong Lim
Ann N Y Acad Sci 2015 Jun;
PMID: 26121488 [PubMed - as supplied by publisher]

Glucocerebrosidase activity in Parkinson's disease with and without GBA mutations.
Roy N Alcalay, Oren A Levy, Cheryl C Waters, Stanley Fahn, Blair Ford, Sheng-Han Kuo, Pietro Mazzoni, Michael W Pauciulo, William C Nichols, Ziv Gan-Or, Guy A Rouleau, Wendy K Chung, Pavlina Wolf, Petra Oliva, Joan Keutzer, Karen Marder, Xiaokui Zhang
Brain 2015 Jun;
PMID: 26117366 [PubMed - as supplied by publisher]

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
Agne Kazlauskaite, R Julio Martínez-Torres, Scott Wilkie, Atul Kumar, Julien Peltier, Alba Gonzalez, Clare Johnson, Jinwei Zhang, Anthony G Hope, Mark Peggie, Matthias Trost, Daan Mf van Aalten, Dario R Alessi, Alan R Prescott, Axel Knebel, Helen Walden, Miratul Mk Muqit
EMBO Rep 2015 Jun;
PMID: 26116755 [PubMed - as supplied by publisher]