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Featured Research

What can we learn by studying exercise and Parkinson's? PDF-funded researcher Kristen Pickett, Ph.D., is using magnetic resonance imaging to help find answers to improve life for people with PD.

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PDF Grant Programs

Are you interested in furthering Parkinson's science? View PDF's open grant programs.

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Genetics and PD

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.


Prevención de Caídas

1) PDF Research Centers

Columbia


http://www.ncbi.nlm.nih.gov/pubmed?term=Columbia%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(alcalay%20rn%5Bau%5D%20OR%20burke%20rb%5BAU%5D%20OR%20clark%20l%5BAU%5D%20OR%20fahn%20s%5BAU%5D%20OR%20Ford%20B%5BAU%5D%20OR%20greene%20l%5BAU%5D%20OR%20greene%20p%5BAU%5D%20OR%20kuo%20sh%5Bau%5D%20OR%20louis%20e%5BAU%5D%20OR%20marder%20k%5BAU%5D%20OR%20mazzoni%20p%5BAU%5D%20OR%20przedborski%20s%5BAU%5D%20OR%20pullman%20s%5BAU%5D%20OR%20stern%20y%5BAU%5D%20OR%20sulzer%20d%5BAU%5D%20OR%20vonsattel%5BAU%5D%20OR%20waters%20c%5BAU%5D%20OR%20yamamoto%20a%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Rush


http://www.ncbi.nlm.nih.gov/pubmed?term=Rush%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Barton%20B%5BAU%5D%20OR%20Bernard%20B%5BAU%5D%20OR%20Comella%20C%5BAU%5D%20OR%20Goldman%20J%5BAU%5D%20OR%20Goetz%20C%5BAU%5D%20OR%20Hall%20D%5BAU%5D%20OR%20Kompoliti%20K%5BAU%5D%20OR%20Kordower%20J%5BAU%5D%20OR%20Shannon%20K%5BAU%5D%20Stebbins%20G%5BAU%5D%20OR%20Verhagen%20L%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Cornell


http://www.ncbi.nlm.nih.gov/pubmed?term=Cornell%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Beal%20MF%5BAU%5D%20OR%20Henchcliffe%20c%5BAU%5D%20OR%20Nirenberg%20m%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

PARKINSON’S DISEASE TOPIC AREAS
Understanding Parkinson’s


Motor Symptoms
    

General

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(motor%5BAll%20Fields%5D%20AND%20(%22diagnosis%22%5BSubheading%5D%20OR%20%22diagnosis%22%5BAll%20Fields%5D%20OR%20%22symptoms%22%5BAll%20Fields%5D%20OR%20%22diagnosis%22%5BMeSH%20Terms%5D%20OR%20%22symptoms%22%5BAll%20Fields%5D))%20NOT%20(%E2%80%9Cnon-motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnon%20motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnonmotor%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)%20AND%20(%22review%22%5BPublication%20Type%5D%20OR%20%22review%20literature%20as%20topic%22%5BMeSH%20Terms%5D%20OR%20%22review%22%5BAll%20Fields%5D)

    Balance and Falls

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Balance%20%5BTIAB%5D%20OR%20Falls%20%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)
    Gait or Freezing

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Gait%5BTIAB%5D%20OR%20Freezing%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Dyskinesia
    Nonmotor Symptoms and Complications

    General
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(%E2%80%9Cnon-motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnon%20motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnonmotor%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Pain
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(pain%5BTI%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Sleep and Fatigue/ REM Behavior Sleep Disorder

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Sleep%5BTIAB%5D%20OR%20Fatigue%5BTIAB%5D%20OR%20%E2%80%9DREM%20behavior%20disorder%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Gastrointestinal and Urinary Function
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Gastrointestinal%5BTIAB%5D%20OR%20Urinary%20%5BTIAB%5D%20OR%20%E2%80%9CBowel%20dysfunction%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9CBladder%20dysfunction%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Cognition and Hallucination

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(cognition%5BTIAB%5D%20OR%20hallucination%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Impulse Control Disorder

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Impulse%20Control%20Disorder%5BTIAB%5D%20OR%20ICD%5BTIAB%5D%20OR%20gambling%5BTIAB%5D%20OR%20shopping%5BTIAB%5D%20OR%20hypersexuality%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Vision/Visual hallucination

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Blurred%20vision%5BTIAB%5D%20OR%20Photophobia%5BTIAB%5D%20OR%20Asthenopia%5BTIAB%5D%20OR%20Double%20vision%5BTIAB%5D%20OR%20Visual%20hallucination%5BTIAB%5D%20OR%20spatial%20relations%5BTIAB%5D%20OR%20color%20perception%5BTIAB%5D)

Oral
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(dental%5BTIAB%5D%20OR%20dysphagia%5BTIAB%5D%20OR%20burning%20mouth%5BTIAB%5D%20OR%20drooling%5BTIAB%5D%20OR%20teeth%5BTIAB%5D%20or%20sialorrhea%5BTIAB%5D%20OR%20gingiva%5BTIAB%5D%20OR%20periodontal%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Speech
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(speech%5BTIAB%5D%20OR%20hypophonia%5BTIAB%5D%20OR%20verbal%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Orthostatic Hypotension
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Orthostatic%20Hypotension%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Etiology/Pathology

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(etiology%5BTIAB%5D%20OR%20pathology%5BTIAB%5D%20OR%20disease%20model%5BTIAB%5D)%20AND%20(%22review%22%5BPublication%20Type%5D%20OR%20%22review%20literature%20as%20topic%22%5BMeSH%20Terms%5D%20OR%20%22review%22%5BAll%20Fields%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Imaging Studies
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(imaging%5BTIAB%5D%20OR%20MRI%5BTIAB%5D%20OR%20fMRI%5BTIAB%5D%20OR%20PET%5BTIAB%5D%20OR%20SPECT%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Clinical Studies

General
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20Clinical%20Trial%5Bptyp%5D%20AND%20(%22last%20180%20days%22%5BDP%5D)

Genetics

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(%22genetics%22%5BSubheading%5D%20OR%20%22genetics%22%5BAll%20Fields%5D%20OR%20%22genetics%22%5BMeSH%20Terms%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Treating Parkinson’s

Current and potential medications/Therapies http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(treatment%5BTI%5D%20OR%20therapy%5BTI%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Surgical Treatments
        
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(stem%20cell%5BTIAB%5D)%20AND%20(treatment%5BTIAB%5D%20OR%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)
    
Gene Therapy
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(gene%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Deep Brain Stimulation
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(gene%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Physical, Occupational and Speech Therapy
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(physical%20therapy%5BTIAB%5D%20OR%20occupational%20therapy%5BTIAB%5D%20OR%20speech%20therapy%5BTIAB%5D%20OR%20rehabilitation%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Nutrition

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(diet%5Btiab%5D%20OR%20nutrition%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Exercise
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(exercise%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Art and Music

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(art%5BTIAB%5D%20OR%20painting%5BTIAB%5D%20OR%20creativity%5BTIAB%5DOR%20music%5BTIAB%5D)%20NOT%20%E2%80%9Cstate%20of%20the%20art%E2%80%9D%5BTIAB%5D%20AND%20(%22last%2090%20days%22%5BDP%5D)


Complementary and Alternative Therapies
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(complementary%20therapy%5BTIAB%5D%20OR%20alternative%20therapy%5BTIAB%5D%20OR%20Adjunct%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Living with a Parkinson’s Diagnosis

Driving
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(driving%5BTIAB%5D%20AND%20(car%5BTIAB%5D%20OR%20automobile%5BTIAB%5D))

Hospitalization


http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(hospitalization%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Care giving
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(caregiver%5BTIAB%5D%20OR%20caregiving%5BTIAB%5D%20OR%20hygiene%5BTIAB%5D%20OR%20dressing%5BTIAB%5D%20OR%20support%20group%5BTIAB%5D%20OR%20health%20care%5BTIAB%5D%20OR%20home%20care%5BTIAB%5D%20OR%20helpline%5BTIAB%5D)AND%20(%22last%2090%20days%22%5BDP%5D)

Hospice/End of Life/Palliative Care
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(hospice%5BTI%5D%20OR%20%E2%80%9Cend%20of%20life%E2%80%9D%5BTI%5D%20OR%20palliative%5BTI%5D)

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Association of the rs1801133 variant in the MTHFR gene and sporadic Parkinson's disease.
S García, Rm Coral-Vázquez, M P Gallegos-Arreola, L A Montes-Almanza, P Canto, F A García-Martínez, G Chavira-Hernández, C Palma-Flores, L Dávila-Maldonado, C F Cuevas-García, L B López Hernández
Folia Neuropathol 2015 ; 53(1):24-8
PMID: 25909872 [PubMed - as supplied by publisher]


Ameliorative effects of baicalein in MPTP-induced mouse model of Parkinson's disease: A microarray study.
Li Gao, Chao Li, Ran-Yao Yang, Wen-Wen Lian, Jian-Song Fang, Xiao-Cong Pang, Xue-Mei Qin, Ai-Lin Liu, Guan-Hua Du
Pharmacol Biochem Behav 2015 Apr;
PMID: 25895692 [PubMed - as supplied by publisher]


The A53E ?-synuclein pathological mutation demonstrates reduced aggregation propensity in vitro and in cell culture.
Nicola J Rutherford, Benoit I Giasson
Neurosci Lett 2015 Apr; 597:43-48
PMID: 25892596 [PubMed - as supplied by publisher]


Vitamin D receptor gene polymorphisms and Parkinson's disease in a population with high ultraviolet radiation exposure.
Nicole M Gatto, Janet S Sinsheimer, Myles Cockburn, Loraine A Escobedo, Yvette Bordelon, Beate Ritz
J Neurol Sci 2015 May; 352(1-2):88-93
PMID: 25890641 [PubMed - as supplied by publisher]


Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with ?-synucleinopathies.
R T Bartus, J H Kordower, E M Johnson, L Brown, B R Kruegel, Y Chu, T L Baumann, A E Lang, C W Olanow, C D Herzog
Neurobiol Dis 2015 Apr; 78:162-171
PMID: 25841760 [PubMed - as supplied by publisher]


Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
M Yue, K M Hinkle, P Davies, E Trushina, F C Fiesel, T A Christenson, A S Schroeder, L Zhang, E Bowles, B Behrouz, S J Lincoln, J E Beevers, A J Milnerwood, A Kurti, P J McLean, J D Fryer, W Springer, D W Dickson, M J Farrer, H L Melrose
Neurobiol Dis 2015 Mar; 78:172-195
PMID: 25836420 [PubMed - as supplied by publisher]


Blood metal levels and related antioxidant enzyme activities in patients with ataxia telangiectasia.
Stefania Squadrone, Paola Brizio, Cecilia Mancini, Elisa Pozzi, Simona Cavalieri, Maria Cesarina Abete, Alfredo Brusco
Neurobiol Dis 2015 Apr;
PMID: 25882094 [PubMed - as supplied by publisher]


Linking a compound-heterozygous Parkin mutant (Q311R and A371T) to Parkinson's disease by using proteomic and molecular approaches.
Sinem Ozgul, Murat Kasap, Gurler Akpinar, Aylin Kanli, Nil Güzel, Kübra Karaosmanoglu, Ahmet Tarik Baykal, Pervin Iseri
Neurochem Int 2015 Apr;
PMID: 25865804 [PubMed - as supplied by publisher]


Variants associated with Gaucher disease in multiple system atrophy.
Jun Mitsui, Takashi Matsukawa, Hidenao Sasaki, Ichiro Yabe, Masaaki Matsushima, Alexandra Dürr, Alexis Brice, Hiroshi Takashima, Akio Kikuchi, Masashi Aoki, Hiroyuki Ishiura, Tsutomu Yasuda, Hidetoshi Date, Budrul Ahsan, Atsushi Iwata, Jun Goto, Yaeko Ichikawa, Yasuo Nakahara, Yoshio Momose, Yuji Takahashi, Kenju Hara, Akiyoshi Kakita, Mitsunori Yamada, Hitoshi Takahashi, Osamu Onodera, Masatoyo Nishizawa, Hirohisa Watanabe, Mizuki Ito, Gen Sobue, Kinya Ishikawa, Hidehiro Mizusawa, Kazuaki Kanai, Takamichi Hattori, Satoshi Kuwabara, Kimihito Arai, Shigeru Koyano, Yoshiyuki Kuroiwa, Kazuko Hasegawa, Tatsuhiko Yuasa, Kenichi Yasui, Kenji Nakashima, Hijiri Ito, Yuishin Izumi, Ryuji Kaji, Takeo Kato, Susumu Kusunoki, Yasushi Osaki, Masahiro Horiuchi, Tomoyoshi Kondo, Shigeo Murayama, Nobutaka Hattori, Mitsutoshi Yamamoto, Miho Murata, Wataru Satake, Tatsushi Toda, Alessandro Filla, Thomas Klockgether, Ullrich Wüllner, Garth Nicholson, Sid Gilman, Caroline M Tanner, Walter A Kukull, Mathew B Stern, Virginia M-Y Lee, John Q Trojanowski, Eliezer Masliah, Phillip A Low, Paola Sandroni, Laurie J Ozelius, Tatiana Foroud, Shoji Tsuji
Ann Clin Transl Neurol 2015 Apr; 2(4):417-26
PMID: 25909086 [PubMed - as supplied by publisher]


Association of TLR4 gene polymorphisms with sporadic Parkinson's disease in a Han Chinese population.
Jing Zhao, Xun Han, Li Xue, Konghua Zhu, Hongxin Liu, Anmu Xie
Neurol Sci 2015 Apr;
PMID: 25908385 [PubMed - as supplied by publisher]


Animal models for prion-like diseases.
Natalia Fernández-Borges, Hasier Eraña, Vanesa Venegas, Saioa R Elezgarai, Chafik Harrathi, Joaquín Castilla
Virus Res 2015 Apr;
PMID: 25907990 [PubMed - as supplied by publisher]


The Potential Application of Mitochondrial Medicine in Toxicologic Poisoning.
David H Jang, Joshua W Lampe, Lance B Becker
J Med Toxicol 2015 Apr;
PMID: 25907836 [PubMed - as supplied by publisher]


The KM-parkin-DB: A Sub-set MutationView Database Specialized for PARK2 (PARKIN) Variants.
Susumu Mitsuyama, Masafumi Ohtsubo, Shinsei Minoshima, Nobuyoshi Shimizu
Hum Mutat 2015 Apr;
PMID: 25907632 [PubMed - as supplied by publisher]


Potential of the cannabinoid CB2 receptor as a pharmacological target against inflammation in Parkinson's disease.
Yolanda Gómez-Gálvez, Cristina Palomo-Garo, Javier Fernández-Ruiz, Concepción García
Prog Neuropsychopharmacol Biol Psychiatry 2015 Apr;
PMID: 25863279 [PubMed - as supplied by publisher]


The association between the C282Y and H63D polymorphisms of HFE gene and the risk of Parkinson's disease: A meta-analysis.
Jianjian Xia, Huamin Xu, Hong Jiang, Junxia Xie
Neurosci Lett 2015 Apr; 595:99-103
PMID: 25863172 [PubMed - as supplied by publisher]


TGF?1 inhibits IFN?-mediated microglia activation and protects mDA neurons from IFN?-driven neurotoxicity.
Xiaolai Zhou, Tanja Zöller, Kerstin Krieglstein, Björn Spittau
J Neurochem 2015 Mar;
PMID: 25827682 [PubMed - as supplied by publisher]


Are striatal tyrosine hydroxylase interneurons dopaminergic?
Harry S Xenias, Osvaldo Ibáñez-Sandoval, Tibor Koós, James M Tepper
J Neurosci 2015 Apr; 35(16):6584-99
PMID: 25904808 [PubMed - as supplied by publisher]


Leucine-Rich Repeat Kinase 2 Deficiency is Protective in Rhabdomyolysis-Induced Kidney Injury.
Ravindra Boddu, Travis D Hull, Subhashini Bolisetty, Xianzhen Hu, Mark S Moehle, João Paulo Lima Daher, Ahmed Ibrahim Kamal, Reny Joseph, James F George, Anupam Agarwal, Lisa M Curtis, Andrew B West
Hum Mol Genet 2015 Apr;
PMID: 25904107 [PubMed - as supplied by publisher]


Is the 1254T>C polymorphism in the DMT1 gene associated with Parkinson's disease?
Selva Moheb Saadat, ?rfan De?irmenci, Serhat Özkan, Faruk Saydam, Zeynep Özdemir Köro?lu, Ertu?rul Çolak, Hasan Veysi Güne?
Neurosci Lett 2015 May; 594:51-4
PMID: 25817364 [PubMed - as supplied by publisher]


Variation in complement protein C1q is not a major contributor to cognitive impairment in Parkinson's disease.
Sophia Carbutt, Jennifer Duff, Alison Yarnall, David J Burn, Gavin Hudson
Neurosci Lett 2015 May; 594:66-9
PMID: 25817358 [PubMed - as supplied by publisher]


The role of ATP13A2 in Parkinson's disease: Clinical phenotypes and molecular mechanisms.
Jin-Sung Park, Nicholas F Blair, Carolyn M Sue
Mov Disord 2015 Apr;
PMID: 25900096 [PubMed - as supplied by publisher]


Parkinson's disease-associated PINK1 G309D mutation increases abnormal phosphorylation of Tau.
Ming Ye, Dai Zhou, Youxin Zhou, Chunming Sun
IUBMB Life 2015 Apr;
PMID: 25899925 [PubMed - as supplied by publisher]


Cellular processes associated with LRRK2 function and dysfunction.
Rebecca Wallings, Claudia Manzoni, Rina Bandopadhyay
FEBS J 2015 Apr;
PMID: 25899482 [PubMed - as supplied by publisher]


Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.
Milena Z Jankovi?, Nikola D Kresojevi?, Valerija S Dobri?i?, Vladana V Markovi?, Igor N Petrovi?, Ivana V Novakovi?, Vladimir S Kosti?
J Neurol Sci 2015 Apr;
PMID: 25899316 [PubMed - as supplied by publisher]


The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system.
João P Lopes, Xavier Morató, Carolina Souza, Cindy Pinhal, Nuno J Machado, Paula M Canas, Henrique B Silva, Igor Stagljar, Jorge Gandía, Víctor Fernández-Dueñas, Rafael Luján, Rodrigo A Cunha, Francisco Ciruela
J Neurochem 2015 Mar;
PMID: 25824528 [PubMed - as supplied by publisher]


Structural characterization of LRRK2 Inhibitors.
Bernd K Gilsbach, Ana C Messias, Genta Ito, Michael Sattler, Dario R Alessi, Alfred Wittinghofer, Arjan Kortholt
J Med Chem 2015 Apr;
PMID: 25897865 [PubMed - as supplied by publisher]


DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson's disease patients.
Shahidee Zainal Abidin, Eng Liang Tan, Soon-Choy Chan, Ameerah Jaafar, Alex Xuen Lee, Mohd Hamdi Noor Abd Hamid, Nor Azian Abdul Murad, Nur Fadlina Pakarul Razy, Shahrul Azmin, Azlina Ahmad Annuar, Shen Yang Lim, Pike-See Cheah, King-Hwa Ling, Norlinah Mohamed Ibrahim
BMC Neurol 2015 Apr; 15(1):59
PMID: 25896831 [PubMed - as supplied by publisher]


Parkinson's disease and alpha-synucleinopathies: from arising pathways to therapeutic challenge.
Fabiana Miraglia, Laura Betti, Lionella Palego, Gino Giannaccini
Cent Nerv Syst Agents Med Chem 2015 Apr;
PMID: 25896035 [PubMed - as supplied by publisher]


New insights on Parkinson's disease genes: the link between mitochondria impairment and neuroinflammation.
Dorit Trudler, Yuval Nash, Dan Frenkel
J Neural Transm 2015 Apr;
PMID: 25894287 [PubMed - as supplied by publisher]


Brain Stimulation for Torsion Dystonia.
Michael D Fox, Ron L Alterman
JAMA Neurol 2015 Apr;
PMID: 25894231 [PubMed - as supplied by publisher]


Synchronized cortico-subthalamic beta oscillations in Parkin-associated Parkinson's disease.
Christian K E Moll, Carsten Buhmann, Alessandro Gulberti, Ulrich Fickel, Monika Poetter-Nerger, Manfred Westphal, Christian Gerloff, Wolfgang Hamel, Andreas K Engel
Clin Neurophysiol 2015 Feb;
PMID: 25891422 [PubMed - as supplied by publisher]


Dopaminergic differentiation of stem cells from human deciduous teeth and their therapeutic benefits for Parkinsonian rats.
Hiromi Fujii, Kohki Matsubara, Kiyoshi Sakai, Mikako Ito, Kinji Ohno, Minoru Ueda, Akihito Yamamoto
Brain Res 2015 Apr;
PMID: 25863132 [PubMed - as supplied by publisher]


Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death.
Shaosong Yang, Li Gao, Fangfang Lu, Bao Wang, Fei Gao, Gang Zhu, Zhibiao Cai, Juan Lai, Qian Yang
J Neuroinflammation 2015 ; 12(1):33
PMID: 25890150 [PubMed - as supplied by publisher]


LRRK2 mutations and neurotoxicant susceptibility.
Jang-Won Lee, Jason R Cannon
Exp Biol Med (Maywood) 2015 Apr;
PMID: 25888648 [PubMed - as supplied by publisher]


Synaptic dysfunction and septin protein family members in neurodegenerative diseases.
Mikael Marttinen, Kaisa Ma Kurkinen, Hilkka Soininen, Annakaisa Haapasalo, Mikko Hiltunen
Mol Neurodegener 2015 ; 10(1):16
PMID: 25888325 [PubMed - as supplied by publisher]


Discriminative analysis of Parkinson's disease based on whole-brain functional connectivity.
Yongbin Chen, Wanqun Yang, Jinyi Long, Yuhu Zhang, Jieying Feng, Yuanqing Li, Biao Huang
PLoS One 2015 ; 10(4):e0124153
PMID: 25885059 [PubMed - as supplied by publisher]


Retraction Note: Gene expression profiling analysis of the putamen for the investigation of compensatory mechanisms in Parkinson's disease.
Lianbo Gao, Honghua Gao, Huan Zhou, Yanyuan Xu
BMC Neurol 2015 ; 15:45
PMID: 25884429 [PubMed - as supplied by publisher]


Adenosine A2A receptor-mediated control of pilocarpine-induced tremulous jaw movements is Parkinson's disease-associated GPR37 receptor-dependent.
Jorge Gandía, Xavier Morató, Igor Stagljar, Víctor Fernández-Dueñas, Francisco Ciruela
Behav Brain Res 2015 Apr;
PMID: 25862943 [PubMed - as supplied by publisher]


Inflammation in Parkinson's disease: role of glucocorticoids.
María-Trinidad Herrero, Cristina Estrada, Layal Maatouk, Sheela Vyas
Front Neuroanat 2015 ; 9:32
PMID: 25883554 [PubMed - as supplied by publisher]


Expression analysis of the long non-coding RNA antisense to Uchl1 (AS Uchl1) during dopaminergic cells' differentiation in vitro and in neurochemical models of Parkinson's disease.
Claudia Carrieri, Alistair R R Forrest, Claudio Santoro, Francesca Persichetti, Piero Carninci, Silvia Zucchelli, Stefano Gustincich
Front Cell Neurosci 2015 ; 9:114
PMID: 25883552 [PubMed - as supplied by publisher]


Alkaptonuria, more than just a mere disease.
Abdul Qayyum Rana, Usman Saeed, Ismael Abdullah
J Neurosci Rural Pract 2015 Apr-Jun; 6(2):257-60
PMID: 25883496 [PubMed - as supplied by publisher]


Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies.
Davide Chiasserini, Silvia Paciotti, Paolo Eusebi, Emanuele Persichetti, Anna Tasegian, Marzena Kurzawa-Akanbi, Patrick F Chinnery, Christopher M Morris, Paolo Calabresi, Lucilla Parnetti, Tommaso Beccari
Mol Neurodegener 2015 Mar; 10(1):15
PMID: 25881142 [PubMed - as supplied by publisher]


Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy.
Nimrod Miller, Zhihua Feng, Brittany M Edens, Ben Yang, Han Shi, Christie C Sze, Benjamin Taige Hong, Susan C Su, Jorge A Cantu, Jacek Topczewski, Thomas O Crawford, Chien-Ping Ko, Charlotte J Sumner, Long Ma, Yong-Chao Ma
J Neurosci 2015 Apr; 35(15):6038-50
PMID: 25878277 [PubMed - as supplied by publisher]


RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.
Núria Martín-Flores, Joan Romaní-Aumedes, Laura Rué, Mercè Canal, Phil Sanders, Marco Straccia, Nicholas D Allen, Jordi Alberch, Josep M Canals, Esther Pérez-Navarro, Cristina Malagelada
Mol Neurobiol 2015 Apr;
PMID: 25876513 [PubMed - as supplied by publisher]


Digital Gene Expression Analysis of Microsporum canis Exposed to Berberine Chloride.
Chen-Wen Xiao, Quan-An Ji, Qiang Wei, Yan Liu, Li-Jun Pan, Guo-Lian Bao
PLoS One 2015 ; 10(4):e0124265
PMID: 25874937 [PubMed - as supplied by publisher]


Neuroprotective Effects of the Cultivated Chondrus crispus in a C. elegans Model of Parkinson's Disease.
Jinghua Liu, Arjun H Banskota, Alan T Critchley, Jeff Hafting, Balakrishnan Prithiviraj
Mar Drugs 2015 ; 13(4):2250-66
PMID: 25874922 [PubMed - as supplied by publisher]


Loss of hfe function reverses impaired recognition memory caused by olfactory manganese exposure in mice.
Qi Ye, Jonghan Kim
Toxicol Res 2015 Mar; 31(1):17-23
PMID: 25874029 [PubMed - as supplied by publisher]


Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated ?-synuclein.
Eduard Bentea, Anke Van der Perren, Joeri Van Liefferinge, Anissa El Arfani, Giulia Albertini, Thomas Demuyser, Ellen Merckx, Yvette Michotte, Ilse Smolders, Veerle Baekelandt, Ann Massie
Front Behav Neurosci 2015 ; 9:68
PMID: 25873870 [PubMed - as supplied by publisher]


Is there a role for ADORA2A polymorphisms in levodopa-induced dyskinesia in Parkinson's disease patients?
Mariana Rieck, Artur F Schumacher-Schuh, Sidia M Callegari-Jacques, Vivian Altmann, Márcio Schneider Medeiros, Carlos Rm Rieder, Mara H Hutz
Pharmacogenomics 2015 Apr; :1-10
PMID: 25872644 [PubMed - as supplied by publisher]


Role of Toll-like receptor/MYD88 signaling in neurodegenerative diseases.
Wang Xiang, Zhang-Yong Chao, Du-Yi Feng
Rev Neurosci 2015 Apr;
PMID: 25870959 [PubMed - as supplied by publisher]


Alpha-synucleinopathy and neuropsychological symptoms in a population-based cohort of the elderly.
Julia Zaccai, Carol Brayne, Fiona E Matthews, Paul G Ince,
Alzheimers Res Ther 2015 ; 7(1):19
PMID: 25870655 [PubMed - as supplied by publisher]


ER proteostasis disturbances in Parkinson's disease: novel insights.
Gabriela Mercado, Valentina Castillo, Rene Vidal, Claudio Hetz
Front Aging Neurosci 2015 ; 7:39
PMID: 25870559 [PubMed - as supplied by publisher]


Glutathione S-transferase T1 and M1 null genotypes and Parkinson's disease risk: evidence from an updated meta-analysis.
Hongzhou Liu, Jie Peng, Jiajia Gao, Fang Zheng, Chaorong Tie
Neurol Sci 2015 Apr;
PMID: 25868597 [PubMed - as supplied by publisher]


CK2beta promotes Pink1/Parkin-mediated MIRO1 degradation].
Chenliang Zhang, Siyue Qin, Chang'an Jiang
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2014 Dec; 31(6):1310-5
PMID: 25868250 [PubMed - as supplied by publisher]


Increased 14-3-3 phosphorylation observed in Parkinson's disease reduces neuroprotective potential of 14-3-3 proteins.
Sunny Rae Slone, Nicholas Lavalley, Michael McFerrin, Bing Wang, Talene Alene Yacoubian
Neurobiol Dis 2015 Apr;
PMID: 25862939 [PubMed - as supplied by publisher]


MPTP's Pathway of Toxicity Indicates Central Role of Transcription Factor SP1.
Alexandra Maertens, Thomas Luechtefeld, Andre Kleensang, Thomas Hartung
Arch Toxicol 2015 May; 89(5):743-55
PMID: 25851821 [PubMed - as supplied by publisher]


Phosphorylated ubiquitin chain is the genuine Parkin receptor.
Kei Okatsu, Fumika Koyano, Mayumi Kimura, Hidetaka Kosako, Yasushi Saeki, Keiji Tanaka, Noriyuki Matsuda
J Cell Biol 2015 Apr; 209(1):111-28
PMID: 25847540 [PubMed - as supplied by publisher]


Genome-wide sperm DNA methylation changes after 3 months of exercise training in humans.
Joshua Denham, Brendan J O'Brien, Jack T Harvey, Fadi J Charchar
Epigenomics 2015 Apr; :1-15
PMID: 25864559 [PubMed - as supplied by publisher]


p53 signalling mediates acupuncture-induced neuroprotection in Parkinson's disease.
Ji-Yeun Park, Hwan Choi, Soonbong Baek, Jaehwan Jang, Ahreum Lee, Songhee Jeon, Jongpil Kim, Hi-Joon Park
Biochem Biophys Res Commun 2015 Mar;
PMID: 25827815 [PubMed - as supplied by publisher]


The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (?-syn) toxicity to rat nigral neurons.
Maxim Salganik, Valeriy G Sergeyev, Vishal Shinde, Craig A Meyers, Marina S Gorbatyuk, Jonathan H Lin, Sergey Zolotukhin, Oleg S Gorbatyuk
Neurobiol Aging 2015 Mar;
PMID: 25863526 [PubMed - as supplied by publisher]


Interplay Between Exosomes, microRNAs and Toll-Like Receptors in Brain Disorders.
Vera Paschon, Silvia Honda Takada, Juliane Midori Ikebara, Erica Sousa, Reza Raeisossadati, Henning Ulrich, Alexandre Hiroaki Kihara
Mol Neurobiol 2015 Apr;
PMID: 25862375 [PubMed - as supplied by publisher]


The potential of LINGO-1 as a therapeutic target for essential tremor.
José Ag Agúndez, Félix Javier Jiménez-Jimenez, Hortensia Alonso-Navarro, Elena García-Martín
Expert Opin Ther Targets 2015 Apr; :1-10
PMID: 25862159 [PubMed - as supplied by publisher]


Convergence of parkin, PINK1 and ?-synuclein on stress-induced mitochondrial morphological remodelling.
Kristi L Norris, Rui Hao, Liang-Fu Chen, Chun-Hsiang Lai, Meghan Kapur, Peter J Shaughnessy, Dennis Chou, Jin Yan, J Paul Taylor, Simone Engelender, Anna E West, Kah-Leong Lim, Tso-Pang Yao
J Biol Chem 2015 Apr;
PMID: 25861987 [PubMed - as supplied by publisher]


Mitochondrial dynamism and heart disease: changing shape and shaping change.
Gerald W Dorn
EMBO Mol Med 2015 Apr;
PMID: 25861797 [PubMed - as supplied by publisher]


Carbidopa-Based Modulation of the Functional Effect of the AAV2-hAADC Gene Therapy in 6-OHDA Lesioned Rats.
Agnieszka Ciesielska, Nitasha Sharma, Janine Beyer, John Forsayeth, Krystof Bankiewicz
PLoS One 2015 ; 10(4):e0122708
PMID: 25860990 [PubMed - as supplied by publisher]


Folic acid supplementation rescues anomalies associated with knockdown of parkin in dopaminergic and serotonergic neurons in Drosophila model of Parkinson's disease.
Saurabh Srivastav, Sandeep Kumar Singh, Amarish Kumar Yadav, Saripella Srikrishna
Biochem Biophys Res Commun 2015 Mar;
PMID: 25824034 [PubMed - as supplied by publisher]


Prolongation of Chemically-Induced Methemoglobinemia in Mice Lacking ?-synuclein: A Novel Pharmacologic and Toxicologic Phenotype.
Yien-Ming Kuo, Robert L Nussbaum
Toxicol Rep 2015; 2:504-511
PMID: 25859428 [PubMed - as supplied by publisher]


OCT: New perspectives in neuro-ophthalmology.
Gema Rebolleda, Laura Diez-Alvarez, Alfonso Casado, Carmen Sánchez-Sánchez, Elisabet de Dompablo, Julio J González-López, Francisco J Muñoz-Negrete
Saudi J Ophthalmol 2015 Jan-Mar; 29(1):9-25
PMID: 25859135 [PubMed - as supplied by publisher]


?-Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2.
Lauren R Kett, Barbara Stiller, Megan M Bernath, Inmaculada Tasset, Javier Blesa, Vernice Jackson-Lewis, Robin B Chan, Bowen Zhou, Gilbert Di Paolo, Serge Przedborski, Ana Maria Cuervo, William T Dauer
J Neurosci 2015 Apr; 35(14):5724-42
PMID: 25855184 [PubMed - as supplied by publisher]


Fine mapping and resequencing of the PARK16 locus in Parkinson's disease.
Lasse Pihlstrøm, Aina Rengmark, Kari Anne Bjørnarå, Nil Dizdar, Camilla Fardell, Lars Forsgren, Björn Holmberg, Jan Petter Larsen, Jan Linder, Hans Nissbrandt, Ole-Bjørn Tysnes, Espen Dietrichs, Mathias Toft
J Hum Genet 2015 Apr;
PMID: 25855069 [PubMed - as supplied by publisher]


Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate.
Petranka Krumova, Lauran Reyniers, Marc Meyer, Evy Lobbestael, Daniela Stauffer, Bertran Gerrits, Lionel Muller, Sjouke Hoving, Klemens Kaupmann, Johannes Voshol, Doriano Fabbro, Andreas Bauer, Giorgio Rovelli, Jean-Marc Taymans, Tewis Bouwmeester, Veerle Baekelandt
FASEB J 2015 Apr;
PMID: 25854701 [PubMed - as supplied by publisher]


iPS models of Parkin and PINK1.
Aleksandar Rakovic, Philip Seibler, Christine Klein
Biochem Soc Trans 2015 Apr; 43(2):302-7
PMID: 25849934 [PubMed - as supplied by publisher]


The endoplasmic reticulum/mitochondria interface: a subcellular platform for the orchestration of the functions of the PINK1-Parkin pathway?
Zoi Erpapazoglou, Olga Corti
Biochem Soc Trans 2015 Apr; 43(2):297-301
PMID: 25849933 [PubMed - as supplied by publisher]


Linking microtubules to Parkinson's disease: the case of parkin.
Graziella Cappelletti, Francesca Casagrande, Alessandra Calogero, Carmelita De Gregorio, Gianni Pezzoli, Daniele Cartelli
Biochem Soc Trans 2015 Apr; 43(2):292-6
PMID: 25849932 [PubMed - as supplied by publisher]


PINK1 activation-turning on a promiscuous kinase.
Liesbeth Aerts, Bart De Strooper, Vanessa A Morais
Biochem Soc Trans 2015 Apr; 43(2):280-6
PMID: 25849930 [PubMed - as supplied by publisher]


Activation of the E3 ubiquitin ligase Parkin.
Thomas R Caulfield, Fabienne C Fiesel, Wolfdieter Springer
Biochem Soc Trans 2015 Apr; 43(2):269-74
PMID: 25849928 [PubMed - as supplied by publisher]


TDP-43 in amyotrophic lateral sclerosis - is it a prion disease?
A C Ludolph, J Brettschneider
Eur J Neurol 2015 May; 22(5):753-61
PMID: 25846565 [PubMed - as supplied by publisher]


Mitochondrial Alterations by PARKIN in Dopaminergic Neurons Using PARK2 Patient-Specific and PARK2 Knockout Isogenic iPSC Lines.
Atossa Shaltouki, Renuka Sivapatham, Ying Pei, Akos A Gerencser, Olga Mom?ilovi?, Mahendra S Rao, Xianmin Zeng
Stem Cell Reports 2015 Apr;
PMID: 25843045 [PubMed - as supplied by publisher]


PET/MR in Dementia and Other Neurodegenerative Diseases.
Henryk Barthel, Matthias L Schroeter, Karl-Titus Hoffmann, Osama Sabri
Semin Nucl Med 2015 May; 45(3):224-233
PMID: 25841277 [PubMed - as supplied by publisher]


Cognitive and behavioral symptoms in Parkinson's disease patients with the G2019S and R1441G mutations of the LRRK2 gene.
Johanne Hatteland Somme, Ana Molano Salazar, Amaia Gonzalez, Beatriz Tijero, Koldo Berganzo, Elena Lezcano, Manuel Fernandez Martinez, Juan Jose Zarranz, Juan Carlos Gómez-Esteban
Parkinsonism Relat Disord 2015 Mar;
PMID: 25840672 [PubMed - as supplied by publisher]


DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease.
Kazuko Takahashi-Niki, Ayako Inafune, Naruyuki Michitani, Yoshitaka Hatakeyama, Kotaro Suzuki, Mai Sasaki, Yoshihisa Kitamura, Takeshi Niki, Sanae M M Iguchi-Ariga, Hiroyoshi Ariga
J Pharmacol Sci 2015 Mar; 127(3):305-10
PMID: 25837927 [PubMed - as supplied by publisher]


Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein.
Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi
PLoS Genet 2015 Apr; 11(4):e1005065
PMID: 25835295 [PubMed - as supplied by publisher]


Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders.
Jenna M Puccini, Daniel F Marker, Tim Fitzgerald, Justin Barbieri, Christopher S Kim, Patrick Miller-Rhodes, Shao-Ming Lu, Stephen Dewhurst, Harris A Gelbard
J Neurosci 2015 Apr; 35(13):5271-83
PMID: 25834052 [PubMed - as supplied by publisher]


Agonists of the tissue-protective erythropoietin receptor in the treatment of Parkinson's disease.
Juha Punnonen, James L Miller, Timothy J Collier, Jeffrey R Spencer
Curr Top Med Chem 2015 ; 15(10):955-69
PMID: 25832721 [PubMed - as supplied by publisher]


Inhibitors of Leucine-Rich Repeat Kinase 2 (LRRK2): Progress and Promise for the Treatment of Parkinson's Disease.
Paul J Gilligan
Curr Top Med Chem 2015 ; 15(10):927-38
PMID: 25832719 [PubMed - as supplied by publisher]


Genomic instability in the PARK2 locus is associated with Parkinson's disease.
Wojciech Ambroziak, Dariusz Koziorowski, Kinga Duszyc, Paulina Górka-Skoczylas, Anna Potulska-Chromik, Jaros?aw S?awek, Dorota Hoffman-Zacharska
J Appl Genet 2015 Apr;
PMID: 25833766 [PubMed - as supplied by publisher]


(11)C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat.
Matthew D Walker, Katherine Dinelle, Rick Kornelsen, Nathan V Lee, Qing Miao, Mike Adam, Christine Takhar, Edwin Mak, Michael Schulzer, Matthew J Farrer, Vesna Sossi
J Cereb Blood Flow Metab 2015 Apr;
PMID: 25833342 [PubMed - as supplied by publisher]


No Dopamine Cell Loss or Changes in Cytoskeleton Function in Transgenic Mice Expressing Physiological Levels of Wild Type or G2019S Mutant LRRK2 and in Human Fibroblasts.
Marta Garcia-Miralles, Janaky Coomaraswamy, Karina Häbig, Martin C Herzig, Natalja Funk, Frank Gillardon, Martina Maisel, Mathias Jucker, Thomas Gasser, Dagmar Galter, Saskia Biskup
PLoS One 2015 ; 10(4):e0118947
PMID: 25830304 [PubMed - as supplied by publisher]


Transcriptomics of Maternal and Fetal Membranes Can Discriminate between Gestational-Age Matched Preterm Neonates with and without Cognitive Impairment Diagnosed at 18-24 Months.
Athina Pappas, Tinnakorn Chaiworapongsa, Roberto Romero, Steven J Korzeniewski, Josef C Cortez, Gaurav Bhatti, Nardhy Gomez-Lopez, Sonia S Hassan, Seetha Shankaran, Adi L Tarca
PLoS One 2015 ; 10(3):e0118573
PMID: 25822971 [PubMed - as supplied by publisher]


Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration.
Durga Praveen Meka, Anne Kathrin Müller-Rischart, Prakash Nidadavolu, Behnam Mohammadi, Elisa Motori, Srinivas Kumar Ponna, Helia Aboutalebi, Mahmoud Bassal, Anil Annamneedi, Barbara Finckh, Margit Miesbauer, Natalie Rotermund, Christian Lohr, Jörg Tatzelt, Konstanze F Winklhofer, Edgar R Kramer
J Clin Invest 2015 Mar;
PMID: 25822020 [PubMed - as supplied by publisher]


Evaluating LRRK2 Genetic Variants with Unclear Pathogenicity.
Fathima Shaffra Refai, Shin Hui Ng, Eng-King Tan
Biomed Res Int 2015 ; 2015:678701
PMID: 25821816 [PubMed - as supplied by publisher]


Gaucher-Associated Parkinsonism.
Yaqiong Li, Ping Li, Huimin Liang, Zhiquan Zhao, Makoto Hashimoto, Jianshe Wei
Cell Mol Neurobiol 2015 Mar;
PMID: 25820783 [PubMed - as supplied by publisher]


Syndromic parkinsonism and dementia associated with OPA1 missense mutations.
Valerio Carelli, Olimpia Musumeci, Leonardo Caporali, Claudia Zanna, Chiara La Morgia, Valentina Del Dotto, Anna Maria Porcelli, Michela Rugolo, Maria Lucia Valentino, Luisa Iommarini, Alessandra Maresca, Piero Barboni, Michele Carbonelli, Costantino Trombetta, Enza Maria Valente, Simone Patergnani, Carlotta Giorgi, Paolo Pinton, Giovanni Rizzo, Caterina Tonon, Raffaele Lodi, Patrizia Avoni, Rocco Liguori, Agostino Baruzzi, Antonio Toscano, Massimo Zeviani
Ann Neurol 2015 Mar;
PMID: 25820230 [PubMed - as supplied by publisher]


The single nucleotide polymorphism Rs12817488 is associated with Parkinson's disease in the Chinese population.
Ri-Li Yu, Ji-Feng Guo, Ya-Qin Wang, Zhen-Hua Liu, Zhan-Fang Sun, Li Su, Yuan Zhang, Xin-Xiang Yan, Bei-Sha Tang
J Clin Neurosci 2015 Mar;
PMID: 25818163 [PubMed - as supplied by publisher]


The structure and function of the dopamine transporter and its role in CNS diseases.
Patrick C McHugh, David A Buckley
Vitam Horm 2015 ; 98:339-69
PMID: 25817874 [PubMed - as supplied by publisher]


Parkinson disease: ?-synuclein mutational screening and new clinical insight into the p.E46K mutation.
Márcia M G Pimentel, Fabíola C Rodrigues, Marco Antônio A Leite, Mário Campos Júnior, Ana Lucia Rosso, Denise H Nicaretta, João S Pereira, Delson José Silva, Marcus V Della Coletta, Luiz Felipe R Vasconcellos, Gabriella M Abreu, Jussara M Dos Santos, Cíntia B Santos-Rebouças
Parkinsonism Relat Disord 2015 Mar;
PMID: 25817515 [PubMed - as supplied by publisher]


Genetic markers of Restless Legs Syndrome in Parkinson disease.
Ziv Gan-Or, Roy N Alcalay, Anat Bar-Shira, Claire S Leblond, Ronald B Postuma, Shay Ben-Shachar, Cheryl Waters, Amelie Johnson, Oren Levy, Anat Mirelman, Mali Gana-Weisz, Nicolas Dupré, Jacques Montplaisir, Nir Giladi, Stanley Fahn, Lan Xiong, Patrick A Dion, Avi Orr-Urtreger, Guy A Rouleau
Parkinsonism Relat Disord 2015 Mar;
PMID: 25817513 [PubMed - as supplied by publisher]


A Peruvian family with a novel PARK2 mutation: Clinical and pathological characteristics.
Mario R Cornejo-Olivas, Luis Torres, Ignacio F Mata, Pilar Mazzetti, Diana Rivas, Carlos Cosentino, Miguel Inca-Martinez, Juan M Cuba, Cyrus P Zabetian, James B Leverenz
Parkinsonism Relat Disord 2015 Jan;
PMID: 25817512 [PubMed - as supplied by publisher]


A Novel GTP-Binding Inhibitor, FX2149, Attenuates LRRK2 Toxicity in Parkinson's Disease Models.
Tianxia Li, Xinhua He, Joseph M Thomas, Dejun Yang, Shijun Zhong, Fengtian Xue, Wanli W Smith
PLoS One 2015 ; 10(3):e0122461
PMID: 25816252 [PubMed - as supplied by publisher]


A Nurr1 Agonist Causes Neuroprotection in a Parkinson's Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C).
Gaynor A Smith, Emily M Rocha, Thomas Rooney, Pascal Barneoud, Jesse R McLean, Jonathan Beagan, Teresia Osborn, Madeleine Coimbra, Yongyi Luo, Penelope J Hallett, Ole Isacson
PLoS One 2015 ; 10(3):e0121072
PMID: 25815475 [PubMed - as supplied by publisher]