Genetics and PD

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Mitochondrial kinases in Parkinson's disease: Converging insights from neurotoxin and genetic models.
Ruben K Dagda, Jianhui Zhu, Charleen T Chu
Mitochondrion 2009 Jun;
PMID: 19563915 [PubMed - as supplied by publisher]

LRRK2 gene variation and its contribution to Parkinson disease.
Coro Paisán-Ruiz
Hum Mutat 2009 Apr; 30(8):1153-1160
PMID: 19472409 [PubMed - as supplied by publisher]

Molecular pathology of the fibroblast growth factor family.
Pavel Krejci, Jirina Prochazkova, Vitezslav Bryja, Alois Kozubik, William R Wilcox
Hum Mutat 2009 Jun;
PMID: 19621416 [PubMed - as supplied by publisher]

The SNP ratio test: pathway analysis of genome-wide association datasets.
Colm O'Dushlaine, Elaine Kenny, Elizabeth A Heron, Ricardo Segurado, Michael Gill, Derek W Morris, Aiden Corvin
Bioinformatics 2009 Jul;
PMID: 19620097 [PubMed - as supplied by publisher]

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model.
Beate Winner, Paula Desplats, Christian Hagl, Jochen Klucken, Robert Aigner, Sonja Ploetz, Jörn Laemke, Alexandra Karl, Ludwig Aigner, Eliezer Masliah, Erich Buerger, Jürgen Winkler
Exp Neurol 2009 Jul;
PMID: 19619535 [PubMed - as supplied by publisher]

Threonine 53 in alpha-synuclein is conserved in long-living non-primate animals.
Knud Larsen, Claus Hedegaard, Mads Frost Bertelsen, Christian Bendixen
Biochem Biophys Res Commun 2009 Jul;
PMID: 19619507 [PubMed - as supplied by publisher]

Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?
Frank Gillardon
J Neurochem 2009 Jun;
PMID: 19545277 [PubMed - as supplied by publisher]

Characterization of serotonin 5-hydroxytryptamine-1A receptor activation using a phospho-extracellular-signal regulated kinase 2 sensor.
Kristin G Huwiler, Thomas Machleidt, Lucas Chase, Bonnie Hanson, Matthew B Robers
Anal Biochem 2009 Jun;
PMID: 19539597 [PubMed - as supplied by publisher]

A patient with parkinsonism related to Gaucher's disease type I successfully treated by unilateral pallidotomy - a 3-year follow-up.
Micha? Sobstyl, Miros?aw Z?bek, Henryk Koziara, Sebastian Dzierz?cki
Neurol Neurochir Pol 2009 May-June; 43(3):293-297
PMID: 19618314 [PubMed - as supplied by publisher]

Genetic and environmental factors for hyperhomocysteinaemia and its clinical implications in Parkinson's disease.
Monika Bia?ecka, Piotr Robowski, Krystyna Honczarenko, Anna Roszmann, Jaros?aw S?awek
Neurol Neurochir Pol 2009 May-June; 43(3):272-285
PMID: 19618311 [PubMed - as supplied by publisher]

Parkin protects Mitochondrial Genome Integrity and supports Mitochondrial DNA Repair.
Oliver Rothfuss, Heike Fischer, Takafumi Hasegawa, Martina Maisel, Petra Leitner, Franziska Miesel, Manu Sharma, Antje Bornemann, Daniela Berg, Thomas Gasser, Nadja Patenge
Hum Mol Genet 2009 Jul;
PMID: 19617636 [PubMed - as supplied by publisher]

A Multitracer Dopaminergic PET Study of Young-Onset Parkinsonian Patients With and Without Parkin Gene Mutations.
Maria-João Ribeiro, Stéphane Thobois, Ebba Lohmann, Sophie Tezenas du Montcel, Suzanne Lesage, Antoine Pelissolo, Bruno Dubois, Luc Mallet, Pierre Pollak, Yves Agid, Emmanuel Broussolle, Alexis Brice, Philippe Remy,
J Nucl Med 2009 Jul;
PMID: 19617340 [PubMed - as supplied by publisher]

DNA damage induces nuclear translocation of parkin.
Shyan-Yuan Kao
J Biomed Sci 2009 Jul; 16(1):67
PMID: 19615059 [PubMed - as supplied by publisher]

Parkin reverses intracellular beta-amyloid accumulation and its negative effects on proteasome function.
Kenneth M Rosen, Charbel E-H Moussa, Han-Kyu Lee, Pravir Kumar, Tohru Kitada, Gangjian Qin, Qinghao Fu, Henry W Querfurth
J Neurosci Res 2009 Jul;
PMID: 19610108 [PubMed - as supplied by publisher]

Isolation of Neural Crest Derived Chromaffin Progenitors from Adult Adrenal Medulla.
Kuei-Fang Chung, Flavie Sicard, Vladimir Vukicevic, Andreas Hermann, Alexander Storch, Wieland B Huttner, Stefan R Bornstein, Monika Ehrhart-Bornstein
Stem Cells 2009 Jul;
PMID: 19609938 [PubMed - as supplied by publisher]

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.
Wei Lin, Emmanouil Metzakopian, Yannis E Mavromatakis, Nan Gao, Nikolaos Balaskas, Hiroshi Sasaki, James Briscoe, Jeffrey A Whitsett, Martyn Goulding, Klaus H Kaestner, Siew-Lan Ang
Dev Biol 2009 Jul;
PMID: 19607821 [PubMed - as supplied by publisher]

Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications.
Hong Qing, Winnie Wong, Edith G McGeer, Patrick L McGeer
Biochem Biophys Res Commun 2009 Jul;
PMID: 19576176 [PubMed - as supplied by publisher]

DNA Methylation of Alzheimer Disease and Tauopathy-Related Genes in Postmortem Brain.
Marta Barrachina, Isidre Ferrer
J Neuropathol Exp Neurol 2009 Jul;
PMID: 19606065 [PubMed - as supplied by publisher]

Frontotemporal lobar degeneration and dementia with Lewy bodies: clinicopathological issues associated with antemortem diagnosis.
Osamu Yokota
Psychogeriatrics 2009 Jun; 9(2):91-102
PMID: 19604332 [PubMed - as supplied by publisher]

Role of the H1 haplotype of microtubule-associated protein tau (MAPT) gene in Greek patients with Parkinson's disease.
Nikolaos Refenes, Juliane Bolbrinker, Georgios Tagaris, Antonio Orlacchio, Nikolaos Drakoulis, Reinhold Kreutz
BMC Neurol 2009 ; 9:26
PMID: 19558713 [PubMed - as supplied by publisher]

Tickled PINK1: Mitochondrial homeostasis and autophagy in recessive Parkinsonism.
Charleen T Chu
Biochim Biophys Acta 2009 Jul;
PMID: 19595762 [PubMed - as supplied by publisher]

Metabolic profiling of Parkinson's disease: evidence of biomarker from gene expression analysis and rapid neural network detection.
Shiek Ahmed, Winkins Santosh, Suresh Kumar, Hema T Thanka Christlet
J Biomed Sci 2009 Jul; 16(1):63
PMID: 19594911 [PubMed - as supplied by publisher]

Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling.
Nina Rawal, Olga Corti, Paola Sacchetti, Hector Osorio-Ardila, Bita Sehat, Alexis Brice, Ernest Arenas
Biochem Biophys Res Commun 2009 Jul;
PMID: 19591802 [PubMed - as supplied by publisher]

Interaction of elongation factor 1-alpha with leucine-rich repeat kinase 2 impairs kinase activity and microtubule bundling in vitro.
F Gillardon
Neuroscience 2009 Jun;
PMID: 19559761 [PubMed - as supplied by publisher]

Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications.
Jin-Qiang Chen, Patrick R Cammarata, Christopher P Baines, James D Yager
Biochim Biophys Acta 2009 Jun;
PMID: 19559056 [PubMed - as supplied by publisher]

Recent advances in cell and gene therapies for Parkinson's disease
Toru Yasuda, Hideki Mochizuki
Nippon Rinsho 2009 Jul; 67(7):1429-38
PMID: 19591298 [PubMed - as supplied by publisher]

A single nucleotide polymorphism in the 3'UTR of the SNCA gene encoding alpha-synuclein is a new potential susceptibility locus for Parkinson disease.
Sotiria Sotiriou, Gretchen Gibney, Andreas D Baxevanis, Robert L Nussbaum
Neurosci Lett 2009 Sep; 461(2):196-201
PMID: 19540308 [PubMed - as supplied by publisher]

Application of serial analysis of gene expression to the study of human genetic disease.
Martin Horan
Hum Genet 2009 Jul;
PMID: 19590894 [PubMed - as supplied by publisher]

Dopamine transporter genetic variants and pesticides in Parkinson's disease.
Beate R Ritz, Angelika D Manthripragada, Sadie Costello, Sarah J Lincoln, Matthew J Farrer, Myles Cockburn, Jeff Bronstein
Environ Health Perspect 2009 Jun; 117(6):964-9
PMID: 19590691 [PubMed - as supplied by publisher]

Serotonin transporter gene polymorphic element 5-HTTLPR increases the risk of sporadic Parkinson's disease in Italy.
Diego Albani, Angelica Vittori, Sara Batelli, Letizia Polito, Stefania De Mauro, Daniela Galimberti, Elio Scarpini, Carlo Lovati, Claudio Mariani, Gianluigi Forloni
Eur Neurol 2009 ; 62(2):120-3
PMID: 19521089 [PubMed - as supplied by publisher]

Tremor.
Jan Raethjen, Günther Deuschl
Curr Opin Neurol 2009 Aug; 22(4):400-5
PMID: 19553813 [PubMed - as supplied by publisher]

Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement.
Hyman M Schipper, Wei Song, Hillel Zukor, Jacob R Hascalovici, David Zeligman
J Neurochem 2009 Jul; 110(2):469-85
PMID: 19457088 [PubMed - as supplied by publisher]

Doxycycline is Neuroprotective Against Nigral Dopaminergic Degeneration by a Dual Mechanism Involving MMP-3.
Yuri Cho, Hyo Son, Eun-Mee Kim, Ji Choi, Sung Kim, In Ji, Dong Choi, Tong Joh, Yoon Kim, Onyou Hwang
Neurotox Res 2009 Jul;
PMID: 19582534 [PubMed - as supplied by publisher]

Genetics and present therapy options in Parkinson's disease: a review
Benjamin Bereznai, Mária Judit Molnar
Ideggyogy Sz 2009 May; 62(5-6):155-63
PMID: 19579663 [PubMed - as supplied by publisher]

Dopamine D(1) Receptor Gene Expression Studies in Unilateral 6-Hydroxydopamine-Lesioned Parkinson's Rat: Effect of 5-HT, GABA, and Bone Marrow Cell Supplementation.
M Nandhu, E Fabia, C Paulose
J Mol Neurosci 2009 Jul;
PMID: 19578995 [PubMed - as supplied by publisher]

Clinical correlates of pathology in the claustrum in Parkinson's disease and dementia with Lewy bodies.
M E Kalaitzakis, R K B Pearce, S M Gentleman
Neurosci Lett 2009 Sep; 461(1):12-5
PMID: 19523504 [PubMed - as supplied by publisher]

GSK3beta polymorphisms, MAPT H1 haplotype and Parkinson's disease in a Greek cohort.
Kallirhoe Kalinderi, Liana Fidani, Zoe Katsarou, Jordi Clarimón, Sevasti Bostantjopoulou, Alexandros Kotsis
Neurobiol Aging 2009 Jun;
PMID: 19573950 [PubMed - as supplied by publisher]

Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions.
Elisa Greggio, Mark R Cookson
ASN Neuro 2009 ; 1(1)
PMID: 19570025 [PubMed - as supplied by publisher]

Enhanced alpha-Synuclein Expression in Human Neurodegenerative Diseases: Pathogenetic and Therapeutic Implications.
Alison L McCormack, Donato A Di Monte
Curr Protein Pept Sci 2009 Oct;
PMID: 19538156 [PubMed - as supplied by publisher]

Emerging role of LRRK2 in human neural progenitor cell cycle progression, survival and differentiation.
Javorina Milosevic, Sigrid C Schwarz, Vera Ogunlade, Anne K Meyer, Alexander Storch, Johannes Schwarz
Mol Neurodegener 2009 ; 4:25
PMID: 19523245 [PubMed - as supplied by publisher]

Aggregation-defective alpha-synuclein mutants inhibit the fibrillation of Parkinson's disease-linked alpha-synuclein variants.
Hyun-Jung Koo, Min Yeong Choi, Hana Im
Biochem Biophys Res Commun 2009 Aug; 386(1):165-9
PMID: 19501571 [PubMed - as supplied by publisher]

Dissembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients.
Hikmet Nural, Ping He, Thomas Beach, Lucia Sue, Weiming Xia, Yong Shen
Mol Neurodegener 2009 ; 4:23
PMID: 19497122 [PubMed - as supplied by publisher]

The DRD2 TaqIA polymorphism associated with changed midbrain volumes in healthy individuals.
A Cerasa, M C Gioia, P Tarantino, A Labate, G Arabia, G Annesi, P Lanza, G Di Palma, V Blasi, A Quattrone
Genes Brain Behav 2009 Jun; 8(4):459-63
PMID: 19476502 [PubMed - as supplied by publisher]

Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusions.
Elisa A Waxman, Jason P Covy, Irene Bukh, Xiaojie Li, Ted M Dawson, Benoit I Giasson
J Neuropathol Exp Neurol 2009 Jul; 68(7):785-96
PMID: 19535993 [PubMed - as supplied by publisher]

PINK1 mutations in a Brazilian cohort of early-onset Parkinson's disease patients.
Clecio Godeiro-Junior, Patricia M de Carvalho-Aguiar, Andre C Felício, Orlando G P Barsottini, Sonia M A Silva, Vanderci Borges, Luiz Augusto F Andrade, Henrique Ballalai Ferraz
Mov Disord 2009 Jun;
PMID: 19562775 [PubMed - as supplied by publisher]

Association of DRD3 and GRIN2B with impulse control and related behaviors in Parkinson's disease.
Jee-Young Lee, Eun Kyung Lee, Sung Sup Park, Ji-Yeon Lim, Hee Jin Kim, Ji Sun Kim, Beom S Jeon
Mov Disord 2009 Jun;
PMID: 19562769 [PubMed - as supplied by publisher]

Some highlights of research on aging with invertebrates, 2009.
Linda Partridge
Aging Cell 2009 Jun;
PMID: 19558590 [PubMed - as supplied by publisher]

NITRIC OXIDE IN CELL SURVIVAL: A JANUS MOLECULE.
Vittorio Calabrese, Carolin Cornelius, Enrico Rizzarelli, Joshua B Owen, Albena T Dinkova-Kostova, D Allan Butterfield
Antioxid Redox Signal 2009 Jun;
PMID: 19558211 [PubMed - as supplied by publisher]

Evidence for the presence of full-length PARK2 mRNA and Parkin protein in human blood.
Murat Kasap, Gurler Akpinar, Ali Sazci, Halil A Idrisoglu, Haluk Vahabo?lu
Neurosci Lett 2009 Sep; 460(3):196-200
PMID: 19501131 [PubMed - as supplied by publisher]

p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis.
Anna Nogalska, Chiara Terracciano, Carla D'Agostino, W King Engel, Valerie Askanas
Acta Neuropathol 2009 Jun;
PMID: 19557423 [PubMed - as supplied by publisher]

Etiology and pathogenesis of Parkinson disease.
Anthony H V Schapira
Neurol Clin 2009 Aug; 27(3):583-603, v
PMID: 19555823 [PubMed - as supplied by publisher]

Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.
A Grünewald, M E Gegg, J-W Taanman, R H King, N Kock, C Klein, A H V Schapira
Exp Neurol 2009 Jun;
PMID: 19500570 [PubMed - as supplied by publisher]

Neuroprotection in a 6-hydroxydopamine-lesioned Parkinson model using lactoferrin-modified nanoparticles.
Rongqin Huang, Liang Han, Jianhua Li, Feiliang Ren, Weilun Ke, Chen Jiang, Yuanying Pei
J Gene Med 2009 Jun;
PMID: 19554623 [PubMed - as supplied by publisher]

Mitochondrial dysfunction and Parkinson's disease genes: insights from Drosophila.
Jeehye Park, Yongsung Kim, Jongkyeong Chung
Dis Model Mech 2009 Jul-Aug; 2(7-8):336-40
PMID: 19553694 [PubMed - as supplied by publisher]

{alpha}-synuclein and Its A30P Mutant Affect Actin Cytoskeletal Structure and Dynamics.
Vítor L Sousa, Serena Bellani, Maila Giannandrea, Malikmohamed Yousuf, Flavia Valtorta, Jacopo Meldolesi, Evelina Chieregatti
Mol Biol Cell 2009 Jun;
PMID: 19553474 [PubMed - as supplied by publisher]

Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.
Yanping Li, Wencheng Liu, Tinmarla F Oo, Lei Wang, Yi Tang, Vernice Jackson-Lewis, Chun Zhou, Kindiya Geghman, Mikhail Bogdanov, Serge Przedborski, M Flint Beal, Robert E Burke, Chenjian Li
Nat Neurosci 2009 Jul; 12(7):826-8
PMID: 19503083 [PubMed - as supplied by publisher]

Role of Synucleins in Alzheimer's Disease.
Leslie Crews, Igor Tsigelny, Makoto Hashimoto, Eliezer Masliah
Neurotox Res 2009 Jun;
PMID: 19551456 [PubMed - as supplied by publisher]

CXCR4 and CXCL12 Expression is Increased in the Nigro-Striatal System of Parkinson's Disease.
Mika Shimoji, Fernando Pagan, Edward Healton, Italo Mocchetti
Neurotox Res 2009 Jun;
PMID: 19551455 [PubMed - as supplied by publisher]

CENTB5 gene expression in human and mouse
Mol Biol (Mosk) 2009 May-Jun; 43(3):407-13
PMID: 19548526 [PubMed - as supplied by publisher]

Genetic analysis of heme oxygenase-1 (HO-1) in German Parkinson's disease patients.
Claudia Funke, Juergen Tomiuk, Olaf Riess, Daniela Berg, Anne S Soehn
J Neural Transm 2009 Jul; 116(7):853-9
PMID: 19475336 [PubMed - as supplied by publisher]

The Neurodegenerative Mitochondriopathies.
Russell H Swerdlow
J Alzheimers Dis 2009 Jun;
PMID: 19542616 [PubMed - as supplied by publisher]

Screening for LRRK2 R1441 mutations in a cohort of PSP patients from Germany.
D Mad?ar, C Schulte, T Gasser
Eur J Neurol 2009 Jun;
PMID: 19538213 [PubMed - as supplied by publisher]

Biophysics of Parkinson's Disease: Structure and Aggregation of alpha-Synuclein.
Vladimir N Uversky, David Eliezer
Curr Protein Pept Sci 2009 Oct;
PMID: 19538146 [PubMed - as supplied by publisher]

Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons.
Frank M J Jacobs, Annemarie J A van der Linden, Yuhui Wang, Lars von Oerthel, Hei Sook Sul, J Peter H Burbach, Marten P Smidt
Development 2009 Jul; 136(14):2363-73
PMID: 19515692 [PubMed - as supplied by publisher]

Kaempferol derivatives prevent oxidative stress-induced cell death in a DJ-1-dependent manner.
Wei Qu, Li Fan, Yun-chul Kim, Shizuma Ishikawa, Sanae M M Iguchi-Ariga, Xiao-Ping Pu, Hiroyoshi Ariga
J Pharmacol Sci 2009 Jun; 110(2):191-200
PMID: 19498271 [PubMed - as supplied by publisher]

Telomere length in peripheral blood mononuclear cells is associated with folate status in men.
Ligi Paul, Marco Cattaneo, Armando D'Angelo, Francesca Sampietro, Isabella Fermo, Cristina Razzari, Gessica Fontana, Nindra Eugene, Paul F Jacques, Jacob Selhub
J Nutr 2009 Jul; 139(7):1273-8
PMID: 19458030 [PubMed - as supplied by publisher]

Activation of p38 MAPK in the substantia nigra leads to nuclear translocation of NF-kappaB in MPTP-treated mice: implication in Parkinson's disease.
S Karunakaran, V Ravindranath
J Neurochem 2009 Jun; 109(6):1791-9
PMID: 19457134 [PubMed - as supplied by publisher]

Regulation of LRRK2 stability by the E3 ubiquitin ligase CHIP.
Xiaodong Ding, Matthew S Goldberg
PLoS One 2009 ; 4(6):e5949
PMID: 19536328 [PubMed - as supplied by publisher]

Activation of phosphatidylinositol-linked D1-like receptor modulates FGF-2 expression in astrocytes via IP3-dependent Ca2+ signaling.
Xinhua Zhang, Zheng Zhou, Dakui Wang, Aiqun Li, Yanqing Yin, Xiaosong Gu, Fei Ding, Xuechu Zhen, Jiawei Zhou
J Neurosci 2009 Jun; 29(24):7766-75
PMID: 19535588 [PubMed - as supplied by publisher]

Mutations in the Parkinson's disease genes, Leucine Rich Repeat Kinase 2 (LRRK2) and Glucocerebrosidase (GBA), are not associated with essential tremor.
Lorraine N Clark, Sergey Kisselev, Naeun Park, Barbara Ross, Miguel Verbitsky, Eileen Rios, Roy N Alcalay, Joseph H Lee, Elan D Louis
Parkinsonism Relat Disord 2009 Jun;
PMID: 19527940 [PubMed - as supplied by publisher]

Nur(R1)turing a Notion on the Etiopathogenesis of Parkinson's Disease.
Howard Federoff
Neurotox Res 2009 Apr;
PMID: 19526279 [PubMed - as supplied by publisher]

Parkinson's disease.
Andrew J Lees, John Hardy, Tamas Revesz
Lancet 2009 Jun; 373(9680):2055-66
PMID: 19524782 [PubMed - as supplied by publisher]

Parkinson's disease and low frequency alleles found together throughout LRRK2.
Coro Paisán-Ruiz, Nicole Washecka, Priti Nath, Andrew B Singleton, Elizabeth H Corder
Ann Hum Genet 2009 Jul; 73(Pt 4):391-403
PMID: 19489756 [PubMed - as supplied by publisher]

Rescue of alpha-synuclein cytotoxicity by insulin-like growth factors.
Shyan-Yuan Kao
Biochem Biophys Res Commun 2009 Jul; 385(3):434-8
PMID: 19470380 [PubMed - as supplied by publisher]

Mice expressing mutant parkin exhibit hallmark features of Parkinson's disease.
Michael P Hart, Acong Xu
J Neurosci 2009 Jun; 29(23):7392-4
PMID: 19515906 [PubMed - as supplied by publisher]

Essential tremor in Parkinson's disease kindreds from a population of similar genetic background.
Cleanthe Spanaki, Andreas Plaitakis
Mov Disord 2009 Jun;
PMID: 19514058 [PubMed - as supplied by publisher]

The G2019S LRRK2 Mutation is Rare in Korean Patients with Parkinson's Disease and Multiple System Atrophy.
Jin-Whan Cho, Sung-Yeon Kim, Sung-Sup Park, Beom S Jeon
J Clin Neurol 2009 Mar; 5(1):29-32
PMID: 19513331 [PubMed - as supplied by publisher]

Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.
Alexandra Doehring, Anja Kirchhof, Jörn Lötsch
Psychiatr Genet 2009 Jun;
PMID: 19512960 [PubMed - as supplied by publisher]

Expression and localization of the Parkin co-regulated gene in mouse CNS suggests a role in ependymal cilia function.
Gabrielle R Wilson, Jacqueline T Tan, Kate M Brody, Juliet M Taylor, Martin B Delatycki, Paul J Lockhart
Neurosci Lett 2009 Aug; 460(1):97-101
PMID: 19463890 [PubMed - as supplied by publisher]

Lewy body dementia.
Jennifer C Hanson, Carol F Lippa
Int Rev Neurobiol 2009 ; 84:215-28
PMID: 19501720 [PubMed - as supplied by publisher]

Expansion of the Parkinson Disease-Associated SNCA-Rep1 Allele Up-Regulates Human {alpha}-Synuclein in Transgenic Mouse Brain.
Kenneth D Cronin, Dongliang Ge, Paul Manninger, Colton Linnertz, Anna Rossoshek, Bonnie M Orrison, David J Bernard, Omar M A El-Agnaf, Michael G Schlossmacher, Robert L Nussbaum, Ornit Chiba-Falek
Hum Mol Genet 2009 Jun;
PMID: 19498036 [PubMed - as supplied by publisher]

Transcranial brain sonography findings in Parkinson's disease: implications for pathogenesis, early diagnosis and therapy.
Uwe Walter
Expert Rev Neurother 2009 Jun; 9(6):835-46
PMID: 19496687 [PubMed - as supplied by publisher]

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.
Suzana Gispert, Filomena Ricciardi, Alexander Kurz, Mekhman Azizov, Hans-Hermann Hoepken, Dorothea Becker, Wolfgang Voos, Kristina Leuner, Walter E Müller, Alexei P Kudin, Wolfram S Kunz, Annabelle Zimmermann, Jochen Roeper, Dirk Wenzel, Marina Jendrach, Moisés García-Arencíbia, Javier Fernández-Ruiz, Leslie Huber, Hermann Rohrer, Miguel Barrera, Andreas S Reichert, Udo Rüb, Amy Chen, Robert L Nussbaum, Georg Auburger
PLoS One 2009 ; 4(6):e5777
PMID: 19492057 [PubMed - as supplied by publisher]

Dual spatial maps of transcript and protein abundance in the mouse brain.
Christopher C Park, Vladislav A Petyuk, Wei-Jun Qian, Richard D Smith, Desmond J Smith
Expert Rev Proteomics 2009 Jun; 6(3):243-9
PMID: 19489697 [PubMed - as supplied by publisher]

Effect of electroacupuncture scalp point-through-point therapy on the expression of tyrosine hydroxylase and dopamine transporter mRNAs in substantia nigra of Parkinson's disease model rats
Shun Wang, Xiu-jie Qi, Di Han
Zhongguo Zhen Jiu 2009 May; 29(5):391-4
PMID: 19489498 [PubMed - as supplied by publisher]

SNCA variants are associated with increased risk for multiple system atrophy.
Sonja W Scholz, Henry Houlden, Claudia Schulte, Manu Sharma, Abi Li, Daniela Berg, Anna Melchers, Reema Paudel, J Raphael Gibbs, Javier Simon-Sanchez, Coro Paisan-Ruiz, Jose Bras, Jinhui Ding, Honglei Chen, Bryan J Traynor, Sampath Arepalli, Ryan R Zonozi, Tamas Revesz, Janice Holton, Nick Wood, Andrew Lees, Wolfgang Oertel, Ullrich Wüllner, Stefano Goldwurm, Maria Teresa Pellecchia, Thomas Illig, Olaf Riess, Hubert H Fernandez, Ramon L Rodriguez, Michael S Okun, Werner Poewe, Gregor K Wenning, John A Hardy, Andrew B Singleton, Thomas Gasser
Ann Neurol 2009 May; 65(5):610-4
PMID: 19475667 [PubMed - as supplied by publisher]

GRN 3'UTR+78 C>T is not associated with risk for Parkinson's disease.
B Jasinska-Myga, C Wider, G Opala, A Krygowska-Wajs, M Barcikowska, K Czyzewski, M Baker, R Rademakers, R J Uitti, M J Farrer, O A Ross, Z K Wszolek
Eur J Neurol 2009 Mar;
PMID: 19473366 [PubMed - as supplied by publisher]

Biotherapies and Parkinson's disease.
P Cesaro, G Fenelon, P Remy
Rev Neurol (Paris) 2009 May;
PMID: 19487002 [PubMed - as supplied by publisher]

Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.
Lichuan Yang, Noel Y Calingasan, Bobby Thomas, Rajnish K Chaturvedi, Mahmoud Kiaei, Elizabeth J Wille, Karen T Liby, Charlotte Williams, Darlene Royce, Renee Risingsong, Eric S Musiek, Jason D Morrow, Michael Sporn, M Flint Beal
PLoS One 2009 ; 4(6):e5757
PMID: 19484125 [PubMed - as supplied by publisher]

Parkin promotes intracellular A{beta}1-42 clearance.
Mark P Burns, Lihua Zhang, G William Rebeck, Henry W Querfurth, Charbel E-H Moussa
Hum Mol Genet 2009 May;
PMID: 19483198 [PubMed - as supplied by publisher]

GIGYF2 mutations are not a frequent cause of familial Parkinson's disease.
Alessio Di Fonzo, Edito Fabrizio, Astrid Thomas, Emiliana Fincati, Roberto Marconi, Michele Tinazzi, Guido J Breedveld, Erik J Simons, Hsin F Chien, Joaquim J Ferreira, Martin W Horstink, Giovanni Abbruzzese, Barbara Borroni, Giovanni Cossu, Alessio Dalla Libera, Giovanni Fabbrini, Marco Guidi, Michele De Mari, Leonardo Lopiano, Emilia Martignoni, Paolo Marini, Marco Onofrj, Alessandro Padovani, Fabrizio Stocchi, Vincenzo Toni, Cristina Sampaio, Egberto R Barbosa, Giuseppe Meco, The Italian Parkinson Genetics Network, Ben A Oostra, Vincenzo Bonifati
Parkinsonism Relat Disord 2009 May;
PMID: 19482505 [PubMed - as supplied by publisher]

Early involvement of the cerebral cortex in Parkinson's disease: convergence of multiple metabolic defects.
Isidre Ferrer
Prog Neurobiol 2009 Jun; 88(2):89-103
PMID: 19482226 [PubMed - as supplied by publisher]

Inducible over-expression of wild type alpha-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death.
Kostas Vekrellis, Maria Xilouri, Evangelia Emmanouilidou, Leonidas Stefanis
J Neurochem 2009 Jun; 109(5):1348-62
PMID: 19476547 [PubMed - as supplied by publisher]

Genetic analysis of Parkin in early onset Parkinson's disease (PD): Novel intron 9 g > a single nucleotide polymorphism and risk of Taiwanese PD.
Yih-Ru Wu, Chun-Hsien Wu, Chih-Ying Chao, Chun-Chieh Kuan, Wan-Ling Zhang, Cheng-Kuang Wang, Chun-Yuh Chang, Yi-Chun Chang, Guey-Jen Lee-Chen, Chung-Mei Chen
Am J Med Genet B Neuropsychiatr Genet 2009 May;
PMID: 19475582 [PubMed - as supplied by publisher]

Dopamine depletion induces distinct compensatory gene expression changes in DARPP-32 signal transduction cascades of striatonigral and striatopallidal neurons.
Bernhard H Meurers, Gustavo Dziewczapolski, Tao Shi, Anton Bittner, Fredrik Kamme, Clifford W Shults
J Neurosci 2009 May; 29(21):6828-39
PMID: 19474310 [PubMed - as supplied by publisher]

Prevalence and clinical features of LRRK2 mutations in patients with Parkinson's disease in southern Spain.
L Gao, P Gómez-Garre, F J Díaz-Corrales, F Carrillo, M Carballo, A Palomino, J Díaz-Martín, R Mejías, P J Vime, J López-Barneo, P Mir
Eur J Neurol 2009 Mar;
PMID: 19473361 [PubMed - as supplied by publisher]

Protective Effects of Resveratrol and Quercetin Against MPP(+) -Induced Oxidative Stress Act by Modulating Markers of Apoptotic Death in Dopaminergic Neurons.
Julie Bournival, Patrik Quessy, Maria-Grazia Martinoli
Cell Mol Neurobiol 2009 May;
PMID: 19466539 [PubMed - as supplied by publisher]

Recombinant Mitochondrial Transcription Factor A with N-terminal Mitochondrial Transduction Domain Increases Respiration and Mitochondrial Gene Expression.
Shilpa Iyer, Ravindar R Thomas, Francisco R Portell, Lisa D Dunham, Caitlin K Quigley, James P Bennett Jr
Mitochondrion 2009 Feb;
PMID: 19460293 [PubMed - as supplied by publisher]

LRRK2 and GBA mutations differentially affect the initial presentation of Parkinson disease.
Z Gan-Or, A Bar-Shira, A Mirelman, T Gurevich, M Kedmi, N Giladi, A Orr-Urtreger
Neurogenetics 2009 May;
PMID: 19458969 [PubMed - as supplied by publisher]

Targeting Cdk5 Activity in Neuronal Degeneration and Regeneration.
Jyotshnabala Kanungo, Ya-Li Zheng, Niranjana Amin, Harish Pant
Cell Mol Neurobiol 2009 May;
PMID: 19455415 [PubMed - as supplied by publisher]