Genetics and PD

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Clinical and Biochemical Differences in Patients Having Parkinson Disease With vs Without GBA Mutations.
Lama M Chahine, Judy Qiang, Emily Ashbridge, James Minger, Dora Yearout, Stacy Horn, Amy Colcher, Howard I Hurtig, Virginia M-Y Lee, Vivianna M Van Deerlin, James B Leverenz, Andrew D Siderowf, John Q Trojanowski, Cyrus P Zabetian, Alice Chen-Plotkin
JAMA Neurol 2013 May; :1-7
PMID: Object id #123323699752 [PubMed - as supplied by publisher]

Specific needs of dopamine neurons for stimulation in order to survive: implication for Parkinson disease.
Patrick P Michel, Damien Toulorge, Serge Guerreiro, Etienne C Hirsch
FASEB J 2013 May;
PMID: Object id #123923699175 [PubMed - as supplied by publisher]

The Role of ?-Adrenergic Blockers in Parkinson's Disease: Possible Genetic and Cell-Signaling Mechanisms.
Khanh Vinh Quoc Luong, Lan Thi Hoàng Nguy Ecirctilde N
Am J Alzheimers Dis Other Demen 2013 May;
PMID: Object id #118723695225 [PubMed - as supplied by publisher]

Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan.
Anil Rana, Michael Rera, David W Walker
Proc Natl Acad Sci U S A 2013 May; 110(21):8638-43
PMID: Object id #169523650379 [PubMed - as supplied by publisher]

Association of P2X7 receptor gene polymorphisms with sporadic Parkinson's disease in a Han Chinese population.
Hongxin Liu, Xun Han, Yongsheng Li, Haiqiang Zou, Anmu Xie
Neurosci Lett 2013 May;
PMID: Object id #165823648388 [PubMed - as supplied by publisher]

Enhanced prostacyclin synthesis by adenoviral gene transfer reduced glial activation and ameliorated dopaminergic dysfunction in hemiparkinsonian rats.
May-Jywan Tsai, Ching-Feng Weng, Nien-Chu Yu, Dann-Ying Liou, Fu-San Kuo, Ming-Chao Huang, Wen-Cheng Huang, Kabik Tam, Song-Kun Shyue, Henrich Cheng
Oxid Med Cell Longev 2013 ; 2013:649809
PMID: Object id #115623691265 [PubMed - as supplied by publisher]

Vesicular integrity in Parkinson's disease.
Shawn P Alter, Gina M Lenzi, Alison I Bernstein, Gary W Miller
Curr Neurol Neurosci Rep 2013 Jul; 13(7):362
PMID: Object id #50223690026 [PubMed - as supplied by publisher]

Functional Genomics Reveals Dysregulation of Cortical Olfactory Receptors in Parkinson Disease: Novel Putative Chemoreceptors in the Human Brain.
Paula Garcia-Esparcia, Agatha Schlüter, Margarita Carmona, Jesús Moreno, Belen Ansoleaga, Benjamín Torrejón-Escribano, Stefano Gustincich, Aurora Pujol, Isidre Ferrer
J Neuropathol Exp Neurol 2013 Jun; 72(6):524-539
PMID: Object id #196923656994 [PubMed - as supplied by publisher]

FBXO7 Immunoreactivity in ?-Synuclein-Containing Inclusions in Parkinson Disease and Multiple System Atrophy.
Tianna Zhao, Lies-Anne Severijnen, Marcel van der Weiden, Ping Pin Zheng, Ben A Oostra, Renate K Hukema, Rob Willemsen, Johan M Kros, Vincenzo Bonifati
J Neuropathol Exp Neurol 2013 Jun; 72(6):482-8
PMID: Object id #196823656991 [PubMed - as supplied by publisher]

Antisense Oligonucleotides: Treating Neurodegeneration at the Level of RNA.
Sarah L Devos, Timothy M Miller
Neurotherapeutics 2013 May;
PMID: Object id #302723686823 [PubMed - as supplied by publisher]

Increased heat shock transcription factor 1 in the cerebellum reverses the deficiency of Purkinje cells in Alzheimer's disease.
Yu-Qing Jiang, Xiu-Li Wang, Xue-Hong Cao, Zeng-You Ye, Li Li, Wen-Qing Cai
Brain Res 2013 May;
PMID: Object id #220723665061 [PubMed - as supplied by publisher]

Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers.
Dasiel O Borroto-Escuela, Annalisa Ravani, Alexander O Tarakanov, Ismel Brito, Manuel Narvaez, Wilber Romero-Fernandez, Fidel Corrales, Luigi F Agnati, Sergio Tanganelli, Luca Ferraro, Kjell Fuxe
Biochem Biophys Res Commun 2013 Apr;
PMID: Object id #92623624386 [PubMed - as supplied by publisher]

Recent advances in quantitative neuroproteomics.
George E Craft, Anshu Chen, Angus C Nairn
Methods 2013 Apr;
PMID: Object id #87723623823 [PubMed - as supplied by publisher]

Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies.
Claudia Manzoni, Patrick A Lewis
FASEB J 2013 May;
PMID: Object id #257723682122 [PubMed - as supplied by publisher]

Blocking LINGO-1 as a Therapy to Promote CNS Repair: From Concept to the Clinic.
Sha Mi, R Blake Pepinsky, Diego Cadavid
CNS Drugs 2013 May;
PMID: Object id #245723681979 [PubMed - as supplied by publisher]

Pramipexole Reduces Phosphorylation of ?-Synuclein at Serine-129.
Kai-Yin Chau, J Mark Cooper, Anthony Henry V Schapira
J Mol Neurosci 2013 May;
PMID: Object id #248123681749 [PubMed - as supplied by publisher]

Longitudinal genetic analyses of Staphylococcus aureus nasal carriage dynamics in a diverse population.
Gowrishankar Muthukrishnan, Ryan P Lamers, Austin Ellis, Vanathy Paramanandam, Alana B Persaud, Sergio Tafur, Christopher L Parkinson, Alexander M Cole
BMC Infect Dis 2013 May; 13(1):221
PMID: Object id #250223679038 [PubMed - as supplied by publisher]

Expression analysis of lrrk1, lrrk2 and lrrk2 splice variants in mice.
Florian Giesert, Andreas Hofmann, Alexander Bürger, Julia Zerle, Karina Kloos, Ulrich Hafen, Luise Ernst, Jingzhong Zhang, Daniela Maria Vogt-Weisenhorn, Wolfgang Wurst
PLoS One 2013 ; 8(5):e63778
PMID: Object id #254723675505 [PubMed - as supplied by publisher]

Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson's Disease.
Yang Liu, Yubo Guo, Sai An, Yuyang Kuang, Xi He, Haojun Ma, Jianfeng Li, Jing Lv, Ning Zhang, Chen Jiang
PLoS One 2013 ; 8(5):e62905
PMID: Object id #253923675438 [PubMed - as supplied by publisher]

Somatic alpha-synuclein mutations in Parkinson's disease: Hypothesis and preliminary data.
Christos Proukakis, Henry Houlden, Anthony H Schapira
Mov Disord 2013 May;
PMID: Object id #189123674490 [PubMed - as supplied by publisher]

The many faces of alpha-synuclein mutations.
Meike Kasten, Christine Klein
Mov Disord 2013 May;
PMID: Object id #190123674458 [PubMed - as supplied by publisher]

SNCA: Major genetic modifier of age at onset of Parkinson's disease.
Kathrin Brockmann, Claudia Schulte, Ann-Kathrin Hauser, Peter Lichtner, Heiko Huber, Walter Maetzler, Daniela Berg, Thomas Gasser
Mov Disord 2013 May;
PMID: Object id #244323674386 [PubMed - as supplied by publisher]

Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction.
Elena Miñones-Moyano, Marc R Friedländer, Joan Pallares, Birgit Kagerbauer, Sílvia Porta, Georgia Escaramís, Isidre Ferrer, Xavier Estivill, Eulàlia Martí
RNA Biol 2013 May; 10(6)
PMID: Object id #241423673382 [PubMed - as supplied by publisher]

The association between glycogen synthase kinase 3 beta polymorphisms and Parkinson's disease susceptibility: A meta-analysis.
Yongsheng Yuan, Qing Tong, Xianju Zhou, Rui Zhang, Zhiqiang Qi, Kezhong Zhang
Gene 2013 Apr;
PMID: Object id #106923628795 [PubMed - as supplied by publisher]

Pre-immunization with an Intramuscular Injection of AAV9-Human Erythropoietin Vectors Reduces the Vector-Mediated Transduction following Re-Administration in Rat Brain.
Chun Yang, Wei-Hua Yang, Sha-Sha Chen, Bao-Feng Ma, Bin Li, Tao Lu, Ting-Yu Qu, Ronald L Klein, Li-Ru Zhao, Wei-Ming Duan
PLoS One 2013 ; 8(5):e63876
PMID: Object id #236723667683 [PubMed - as supplied by publisher]

Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human ?-Synuclein.
Theodore A Sarafian, Christopher M Ryan, Puneet Souda, Eliezer Masliah, Upendra K Kar, Harry V Vinters, Gary W Mathern, Kym F Faull, Julian P Whitelegge, Joseph B Watson
PLoS One 2013 ; 8(5):e63557
PMID: Object id #235323667637 [PubMed - as supplied by publisher]

Do Tardive Dyskinesia and L-Dopa Induced Dyskinesia Share Common Genetic Risk Factors? An Exploratory Study.
Lior Greenbaum, Stefano Goldwurm, Polina Zozulinsky, Tzuri Lifschytz, Oren S Cohen, Gilad Yahalom, Roberto Cilia, Silvana Tesei, Rosanna Asselta, Rivka Inzelberg, Yoav Kohn, Sharon Hassin-Baer, Bernard Lerer
J Mol Neurosci 2013 May;
PMID: Object id #232223666822 [PubMed - as supplied by publisher]

Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of ?-synuclein in Parkinson's disease models.
Michaeline L Hebron, Irina Lonskaya, Charbel E-H Moussa
Hum Mol Genet 2013 May;
PMID: Object id #228223666528 [PubMed - as supplied by publisher]

The role of inflammation in sporadic and familial Parkinson's disease.
Michela Deleidi, Thomas Gasser
Cell Mol Life Sci 2013 May;
PMID: Object id #226023665870 [PubMed - as supplied by publisher]

Microfluidic-based Electrotaxis for On-demand Quantitative Analysis of Caenorhabditis elegans' Locomotion.
Justin Tong, Pouya Rezai, Sangeena Salam, P Ravi Selvaganapathy, Bhagwati P Gupta
J Vis Exp 2013 ; (75)
PMID: Object id #223123665669 [PubMed - as supplied by publisher]

Study on the levels of DA and metabolite in striatum in rats with Parkinson's disease treated by BDNF gene modified bone mesenchymal stem cells].
Gang-Yong Zhao, Lei Cui, Juan Gao, Rui-Ting Dai, Ping Zhang
Zhongguo Ying Yong Sheng Li Xue Za Zhi 2013 Jan; 29(1):82-5
PMID: Object id #216623662416 [PubMed - as supplied by publisher]

Sustained resistance to acute MPTP toxicity by hypothalamic dopamine neurons following chronic neurotoxicant exposure is associated with sustained up-regulation of parkin protein.
Matthew Benskey, Ki Yong Lee, Kevin Parikh, Keith J Lookingland, John L Goudreau
Neurotoxicology 2013 May;
PMID: Object id #148023643664 [PubMed - as supplied by publisher]

Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster.
Jéssie Haigert Sudati, Francielli Araújo Vieira, Sandra Sartoretto Pavin, Glaecir Roseni Mundstock Dias, Rodrigo Lopes Seeger, Ronaldo Golombieski, Margareth Linde Athayde, Félix Antunes Soares, João Batista Teixeira Rocha, Nilda Vargas Barbosa
Neurotoxicology 2013 Apr;
PMID: Object id #144423639798 [PubMed - as supplied by publisher]

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1-/- mice.
Thi A Nguyen, Tamy Frank-Cannon, Terina N Martinez, Kelly A Ruhn, Marian Marvin, Bradford Casey, Isaac Treviño, John J Hong, Matthew S Goldberg, Malú G Tansey
J Neuroinflammation 2013 ; 10(1):50
PMID: Object id #85423622116 [PubMed - as supplied by publisher]

Genetic susceptibility testing for neurodegenerative diseases: Ethical and practice issues.
J Scott Roberts, Wendy R Uhlmann
Prog Neurobiol 2013 Apr;
PMID: Object id #281423583530 [PubMed - as supplied by publisher]

Mitochondrial Diseases of the Brain.
Rajnish K Chaturvedi, M Flint Beal
Free Radic Biol Med 2013 Apr;
PMID: Object id #327823567191 [PubMed - as supplied by publisher]

Prolyl oligopeptidase colocalizes with ?-synuclein, ?-amyloid, tau protein and astroglia in the post-mortem brain samples with Parkinson's and Alzheimer's diseases.
M J Hannula, T T Myöhänen, J Tenorio-Laranga, P T Männistö, J A Garcia-Horsman
Neuroscience 2013 Jul; 242:140-50
PMID: Object id #345623562579 [PubMed - as supplied by publisher]

Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation.
Jean-François Trempe, Véronique Sauvé, Karl Grenier, Marjan Seirafi, Matthew Y Tang, Marie Ménade, Sameer Al-Abdul-Wahid, Jonathan Krett, Kathy Wong, Guennadi Kozlov, Bhushan Nagar, Edward A Fon, Kalle Gehring
Science 2013 May;
PMID: Object id #217423661642 [PubMed - as supplied by publisher]

Effects of entacapone on plasma homocysteine in Parkinson's disease patients on levodopa].
Peng Zhao, Jun-Feng Yang, Wei Liu, Yu Wang, Ya-Nan Sun, Qi Li, Wei Zhang, Ben-Shu Zhang
Zhonghua Yi Xue Za Zhi 2013 Feb; 93(7):512-5
PMID: Object id #215223660319 [PubMed - as supplied by publisher]

Use of "MGE Enhancers" for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons.
Ying-Jiun J Chen, Daniel Vogt, Yanling Wang, Axel Visel, Shanni N Silberberg, Cory R Nicholas, Teruko Danjo, Joshua L Pollack, Len A Pennacchio, Stewart Anderson, Yoshiki Sasai, Scott C Baraban, Arnold R Kriegstein, Arturo Alvarez-Buylla, John L R Rubenstein
PLoS One 2013 ; 8(5):e61956
PMID: Object id #209623658702 [PubMed - as supplied by publisher]

Edaravone Prevents Neurotoxicity of Mutant L166P DJ-1 in Parkinson's Disease.
Bing Li, Dawei Yu, Zhiying Xu
J Mol Neurosci 2013 May;
PMID: Object id #197423657982 [PubMed - as supplied by publisher]

Ataxin-3 and its e3 partners: implications for machado-joseph disease.
Thomas M Durcan, Edward A Fon
Front Neurol 2013 ; 4:46
PMID: Object id #194523653622 [PubMed - as supplied by publisher]

Absence of A673T amyloid-? precursor protein variant in Alzheimer's disease and other neurological diseases.
Simon Kang Seng Ting, Mei-Sian Chong, Nagaendran Kandiah, Shahul Hameed, Louis Tan, Wing-Lok Au, Kumar M Prakash, Ratnagopal Pavanni, Tih-Shih Lee, Jia-Nee Foo, Jin-Xin Bei, Xue-Qing Yu, Jian-Jun Liu, Yi Zhao, Wei-Ling Lee, Eng-King Tan
Neurobiol Aging 2013 May;
PMID: Object id #180923652020 [PubMed - as supplied by publisher]

P268S in NOD2 associates with susceptibility to Parkinson's disease in Chinese population.
Qilin Ma, Xingkai An, Zhiming Li, Huanjing Zhang, Wenqing Huang, Liangliang Cai, Peng Hu, Qing Lin, Chi-Meng Tzeng
Behav Brain Funct 2013 May; 9(1):19
PMID: Object id #176723651603 [PubMed - as supplied by publisher]

In vivo visualization and monitoring of viable neural stem cells using noninvasive bioluminescence imaging in the 6-hydroxydopamine-induced mouse model of Parkinson disease.
Hyung-Jun Im, Do Won Hwang, Han Kyu Lee, Jaeho Jang, Song Lee, Hyewon Youn, Yeona Jin, Seung U Kim, E Edmund Kim, Yong Sik Kim, Dong Soo Lee
Mol Imaging 2013 Jun; 12(4):224-34
PMID: Object id #172323651500 [PubMed - as supplied by publisher]

Uridine Prodrug Improves Memory in Tg2576 and TAPP Mice and Reduces Pathological Factors associated with Alzheimer's Disease in Related Models.
Joel A Saydoff, Ana Olariu, Jin Sheng, Zhongyi Hu, Qin Li, Rolando Garcia, Jiong Pei, Grace Y Sun, Reid von Borstel
J Alzheimers Dis 2013 May;
PMID: Object id #168523648515 [PubMed - as supplied by publisher]

The remarkable conformational plasticity of alpha-synuclein: blessing or curse?
Angélique Deleersnijder, Melanie Gerard, Zeger Debyser, Veerle Baekelandt
Trends Mol Med 2013 May;
PMID: Object id #163123648364 [PubMed - as supplied by publisher]

Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120).
Christopher D Herzog, Lamar Brown, Brian R Kruegel, Alistair Wilson, Malú G Tansey, Fred H Gage, Eugene M Johnson, Raymond T Bartus
Neurobiol Dis 2013 Apr;
PMID: Object id #108523631873 [PubMed - as supplied by publisher]

Mice lacking the Parkinson's related GPR37/PAEL receptor show non-motor behavioral phenotypes: age and gender effect.
S Mandillo, E Golini, D Marazziti, C Di Pietro, R Matteoni, G P Tocchini-Valentini
Genes Brain Behav 2013 Apr;
PMID: Object id #318123574697 [PubMed - as supplied by publisher]

Short- and Long-Term Effects of LRRK2 on Axon and Dendrite Growth.
Bryan Sepulveda, Roxana Mesias, Xianting Li, Zhenyu Yue, Deanna L Benson
PLoS One 2013 ; 8(4):e61986
PMID: Object id #159323646112 [PubMed - as supplied by publisher]

Longitudinal assessment of tau and amyloid beta in cerebrospinal fluid of Parkinson disease.
Jing Zhang, Hayley A Mattison, Changqin Liu, Carmen Ginghina, Peggy Auinger, Michael P McDermott, Tessandra Stewart, Un Jung Kang, , Kevin C Cain, Min Shi
Acta Neuropathol 2013 May;
PMID: Object id #153723644819 [PubMed - as supplied by publisher]

Assessing neurodegenerative phenotypes in Drosophila dopaminergic neurons by climbing assays and whole brain immunostaining.
Maria Cecilia Barone, Dirk Bohmann
J Vis Exp 2013 ; (74)
PMID: Object id #150023644755 [PubMed - as supplied by publisher]

EIF4G1 Ala502Val and Arg1205His variants in Chinese patients with Parkinson disease.
Lamei Yuan, Zhi Song, Hongbo Xu, Shaojuan Gu, Anding Zhu, Lina Gong, Yongxiang Zhao, Hao Deng
Neurosci Lett 2013 May; 543:69-71
PMID: Object id #348423562511 [PubMed - as supplied by publisher]

Biased Homozygous Haplotypes Across the Human Caveolin 1 Upstream Purine Complex in Parkinson's Disease.
Hossein Darvish, Abolfazl Heidari, Saman Hosseinkhani, Abolfazl Movafagh, Ali Khaligh, Javad Jamshidi, Hamid Noorollahi-Moghaddam, Hamid Reza Heidari-Rostami, Siamak Karkheiran, Gholam-Ali Shahidi, Mansoureh Togha, Seyed Mohammad Hassan Paknejad, Hossein Ashrafian, Siamak Abdi, Saghar Ghasemi Firouzabadi, Seyed Hamid Jamaldini, Mina Ohadi
J Mol Neurosci 2013 May;
PMID: Object id #145423640536 [PubMed - as supplied by publisher]

Age-mediated transcriptomic changes in adult mouse substantia nigra.
Lin Gao, María Hidalgo-Figueroa, Luis M Escudero, Juan Díaz-Martín, José López-Barneo, Alberto Pascual
PLoS One 2013 ; 8(4):e62456
PMID: Object id #138423638090 [PubMed - as supplied by publisher]

Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants.
Giovanni Esposito, Melissa Vos, Sven Vilain, Jef Swerts, Jorge De Sousa Valadas, Stefanie Van Meensel, Onno Schaap, Patrik Verstreken
PLoS Genet 2013 Apr; 9(4):e1003478
PMID: Object id #130623637640 [PubMed - as supplied by publisher]

Letter to the Editor: sTNFr1 and It's Contributory Role in the Evolution and Progression of Different Psychiatric Disorders.
S Kapoor
J Nutr Health Aging 2013 ; 17(5):492
PMID: Object id #112423636553 [PubMed - as supplied by publisher]

Non-Parkinson movement disorders: Five new things.
Mark S Ledoux
Neurol Clin Pract 2013 Feb; 3(1):22-29
PMID: Object id #109523634381 [PubMed - as supplied by publisher]

Cell clocks and neuronal networks: neuron ticking and synchronization in aging and aging - related neurodegenerative disease.
M Bonaconsa, V Colavito, F Pifferi, F Aujard, E Schenker, S Dix, G Grassi-Zucconi, M Bentivoglio, G Bertini
Curr Alzheimer Res 2013 Apr;
PMID: Object id #100223627753 [PubMed - as supplied by publisher]

Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS).
Olena Korvatska, Nicholas S Strand, Jason D Berndt, Tim Strovas, Dong-Hui Chen, James B Leverenz, Konstantin Kiianitsa, Ignacio F Mata, Emre Karakoc, J Lynne Greenup, Emily Bonkowski, Joseph Chuang, Randall T Moon, Evan E Eichler, Deborah A Nickerson, Cyrus P Zabetian, Brian C Kraemer, Thomas D Bird, Wendy H Raskind
Hum Mol Genet 2013 Apr;
PMID: Object id #16123595882 [PubMed - as supplied by publisher]

Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients.
Raymond T Bartus, Tiffany L Baumann, Joao Siffert, Christopher D Herzog, Ron Alterman, Nicholas Boulis, Dennis A Turner, Mark Stacy, Anthony E Lang, Andres M Lozano, C Warren Olanow
Neurology 2013 Apr; 80(18):1698-701
PMID: Object id #312423576625 [PubMed - as supplied by publisher]

Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection.
Jean-François Trempe, Edward A Fon
Front Neurol 2013 ; 4:38
PMID: Object id #99823626584 [PubMed - as supplied by publisher]

LXR Agonists: New Potential Therapeutic Drug for Neurodegenerative Diseases.
Pei Xu, Dabing Li, Xiaotong Tang, Xiaohang Bao, Jing Huang, Yongping Tang, Yang Yang, Haiwei Xu, Xiaotang Fan
Mol Neurobiol 2013 Apr;
PMID: Object id #97823625315 [PubMed - as supplied by publisher]

Association between G2385R and R1628P polymorphism of LRRK2 gene and sporadic Parkinson's disease in a Han-Chinese population in south-eastern China.
Jiangping Cai, Yi Lin, Wanjin Chen, Qifang Lin, Bin Cai, Ning Wang, Weihong Zheng
Neurol Sci 2013 Apr;
PMID: Object id #93623624603 [PubMed - as supplied by publisher]

Resetting Parkinson's disease patient-derived cells to unveil new pathological marks].
Emmanuel Nivet, Guang-Hui Liu, Nuria Montserrat, Juan Carlos Izpisua Belmonte
Med Sci (Paris) 2013 Apr; 29(4):353-5
PMID: Object id #81723621928 [PubMed - as supplied by publisher]

Specific transfection of inflamed brain by macrophages: a new therapeutic strategy for neurodegenerative diseases.
Matthew J Haney, Yuling Zhao, Emily B Harrison, Vivek Mahajan, Shaheen Ahmed, Zhijian He, Poornima Suresh, Shawn D Hingtgen, Natalia L Klyachko, R Lee Mosley, Howard E Gendelman, Alexander V Kabanov, Elena V Batrakova
PLoS One 2013 ; 8(4):e61852
PMID: Object id #80123620794 [PubMed - as supplied by publisher]

PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Yun Chen, Gerald W Dorn
Science 2013 Apr; 340(6131):471-5
PMID: Object id #70123620051 [PubMed - as supplied by publisher]

Analysis of EIF4G1 in ethnic Chinese.
Kai Li, Bei-Sha Tang, Ji-Feng Guo, Ming-Xing Lou, Zhan-Yun Lv, Zhen-Hua Liu, Yun Tian, Cheng-Yuan Song, Kun Xia, Xin-Xiang Yan
BMC Neurol 2013 Apr; 13(1):38
PMID: Object id #64923617574 [PubMed - as supplied by publisher]

High-Resolution Survey in Familial Parkinson Disease Genes Reveals Multiple Independent Copy Number Variation Events in PARK2.
Liyong Wang, Karen Nuytemans, Guney Bademci, Cherylyn Jauregui, Eden R Martin, William K Scott, Jeffery M Vance, Stephan Zuchner
Hum Mutat 2013 Apr;
PMID: Object id #63723616242 [PubMed - as supplied by publisher]

The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration.
Maddalena Costanzo, Chiara Zurzolo
Biochem J 2013 May; 452(1):1-17
PMID: Object id #60823614720 [PubMed - as supplied by publisher]

Genetic variation in the human brain dopamine system influences motor learning and its modulation by L-dopa.
Kristin M Pearson-Fuhrhop, Brian Minton, Daniel Acevedo, Babak Shahbaba, Steven C Cramer
PLoS One 2013 ; 8(4):e61197
PMID: Object id #56923613810 [PubMed - as supplied by publisher]

Association between the BDNF G196A and C270T polymorphisms and Parkinson's disease: A meta-analysis.
Limeng Dai, Dongmei Wang, Meng Hui, Kun Zhang, Liyuan Fu, Yuanyuan Wu, Yun Bai
Int J Neurosci 2013 Apr;
PMID: Object id #37623611539 [PubMed - as supplied by publisher]

Elevated TRAF2/6 expression in Parkinson's disease is caused by the loss of Parkin E3 ligase activity.
Ji-Yun Chung, Hee Ra Park, Su-Jin Lee, Sun-Hye Lee, Jin Sik Kim, Youn-Sang Jung, Sang Hyun Hwang, Nam-Chul Ha, Won-Gi Seol, Jaewon Lee, Bum-Joon Park
Lab Invest 2013 Apr;
PMID: Object id #32523608757 [PubMed - as supplied by publisher]

SLC1A2 variant associated with essential tremor but not Parkinson disease in Chinese subjects.
Eng-King Tan, Jia-Nee Foo, Louis Tan, Wing-Lok Au, Kumar M Prakash, Ebonne Ng, M Kamran Ikram, Tien-Yin Wong, Jian-Jun Liu, Yi Zhao
Neurology 2013 Apr; 80(17):1618-9
PMID: Object id #18923596072 [PubMed - as supplied by publisher]

?-Synuclein in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment.
Ane Korff, Changqin Liu, Carmen Ginghina, Min Shi, Jing Zhang
J Alzheimers Dis 2013 Apr;
PMID: Object id #31823603399 [PubMed - as supplied by publisher]

Direct and Retrograde Transduction of Nigral Neurons with AAV6, 8 and 9, and Intraneuronal Persistence of Viral Particles.
Karin Irmgard Loew, Patrick Aebischer, Bernard Laurent Schneider
Hum Gene Ther 2013 Apr;
PMID: Object id #28923600720 [PubMed - as supplied by publisher]

The Parkinson's disease associated LRRK2 mutation R1441G inhibits neuronal differentiation of neural stem cells.
Lamia'a Bahnassawy, Sarah Nicklas, Thomas Palm, Ingeborg Menzl, Fabian Birzele, Frank Gillardon, Jens Christian Schwamborn
Stem Cells Dev 2013 Apr;
PMID: Object id #27423600457 [PubMed - as supplied by publisher]

PPARs for Brain Disorders.
Benjamin Rolland, Régis Bordet
Curr Drug Targets 2013 Apr;
PMID: Object id #24823597017 [PubMed - as supplied by publisher]

Perspective: Identification of genetic variants associated with dopaminergic compensatory mechanisms in early Parkinson's disease.
Lior Greenbaum, Mordechai Lorberboym, Eldad Melamed, Amihai Rigbi, Yael Barhum, Yoav Kohn, Alexander Khlebtovsky, Bernard Lerer, Ruth Djaldetti
Front Neurosci 2013 ; 7:52
PMID: Object id #35023596382 [PubMed - as supplied by publisher]

Manganese homeostasis and transport.
Jerome Roth, Silvia Ponzoni, Michael Aschner
Met Ions Life Sci 2013 ; 12:169-201
PMID: Object id #11923595673 [PubMed - as supplied by publisher]

Striatal molecular signature of subchronic subthalamic nucleus high frequency stimulation in parkinsonian rat.
Sylviane Lortet, Emilie Lacombe, Nicolas Boulanger, Pascal Rihet, Catherine Nguyen, Lydia Kerkerian-Le Goff, Pascal Salin
PLoS One 2013 ; 8(4):e60447
PMID: Object id #11423593219 [PubMed - as supplied by publisher]

Drosophila DJ-1 Decreases Neural Sensitivity to Stress by Negatively Regulating Daxx-Like Protein through dFOXO.
Soojin Hwang, Saera Song, Yoon Ki Hong, Gahee Choi, Yoon Seok Suh, Seung Yeop Han, Minjung Lee, Seung Hwan Park, Jang Ho Lee, Soojin Lee, Se Min Bang, Yuji Jeong, Won-Ju Chung, Im-Soon Lee, Gilsang Jeong, Jongkyeong Chung, Kyoung Sang Cho
PLoS Genet 2013 Apr; 9(4):e1003412
PMID: Object id #260823593018 [PubMed - as supplied by publisher]

Parkin-Knockout Mice did not Display Increased Vulnerability to Intranasal Administration of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Aderbal S Aguiar, Fabrine S M Tristão, Majid Amar, Caroline Chevarin, Laurence Lanfumey, Raymond Mongeau, Olga Corti, Rui D Prediger, Rita Raisman-Vozari
Neurotox Res 2013 Apr;
PMID: Object id #271323588969 [PubMed - as supplied by publisher]

PINK1 Deficiency Enhances Inflammatory Cytokine Release from Acutely Prepared Brain Slices.
Jun Kim, Ji-Won Byun, Insup Choi, Beomsue Kim, Hey-Kyeong Jeong, Ilo Jou, Eunhye Joe
Exp Neurobiol 2013 Mar; 22(1):38-44
PMID: Object id #274723585721 [PubMed - as supplied by publisher]

Role of oxidative stress in Parkinson's disease.
Onyou Hwang
Exp Neurobiol 2013 Mar; 22(1):11-7
PMID: Object id #277823585717 [PubMed - as supplied by publisher]

Lysosomal impairment in Parkinson's disease.
Benjamin Dehay, Marta Martinez-Vicente, Guy A Caldwell, Kim A Caldwell, Zhenyue Yue, Mark R Cookson, Christine Klein, Miquel Vila, Erwan Bezard
Mov Disord 2013 Apr;
PMID: Object id #284123580333 [PubMed - as supplied by publisher]

Molecular events underlying Parkinson's disease - an interwoven tapestry.
Kah-Leong Lim, Cheng-Wu Zhang
Front Neurol 2013 ; 4:33
PMID: Object id #286223580245 [PubMed - as supplied by publisher]

Loss of ?-Glucocerebrosidase Activity Does Not Affect Alpha-Synuclein Levels or Lysosomal Function in Neuronal Cells.
Georgia Dermentzaki, Evangelia Dimitriou, Maria Xilouri, Helen Michelakakis, Leonidas Stefanis
PLoS One 2013 ; 8(4):e60674
PMID: Object id #280723580063 [PubMed - as supplied by publisher]

PET Imaging of Neuropathology in Tauopathies: Progressive Supranuclear Palsy.
Vladimir Kepe, Yvette Bordelon, Adam Boxer, Sung-Cheng Huang, Jie Liu, Frederick C Thiede, John C Mazziotta, Mario F Mendez, Natacha Donoghue, Gary W Small, Jorge R Barrio
J Alzheimers Dis 2013 Apr;
PMID: Object id #294323579330 [PubMed - as supplied by publisher]

Diversity of mitochondrial pathology in a mouse model of axonal degeneration in synucleinopathies.
Akio Sekigawa, Yoshiki Takamatsu, Kazunari Sekiyama, Takato Takenouchi, Shuei Sugama, Masaaki Waragai, Masayo Fujita, Makoto Hashimoto
Oxid Med Cell Longev 2013 ; 2013:817807
PMID: Object id #300023577227 [PubMed - as supplied by publisher]

Boron Enhances Odontogenic and Osteogenic Differentiation of Human Tooth Germ Stem Cells (hTGSCs) In Vitro.
Pakize Neslihan Ta?l?, Ay?egül Do?an, Selami Demirci, Fikrettin Sahin
Biol Trace Elem Res 2013 Apr;
PMID: Object id #315523575901 [PubMed - as supplied by publisher]

Co-Enzyme Q10 to Treat Neurological Disorders: Basic Mechanisms, Clinical Outcomes, and Future Research Direction.
M Salama, T F Yuan, S Machado, E Murillo-Rodríguez, J A Vega, M Menéndez-González, A E Nardi, O Arias-Carrión
CNS Neurol Disord Drug Targets 2013 Apr;
PMID: Object id #320923574157 [PubMed - as supplied by publisher]

IL6-gene variation in Parkinson's disease.
Phillip G Sand
Can J Neurol Sci 2013 Mar; 40(2):268
PMID: Object id #323923573561 [PubMed - as supplied by publisher]

Immunotherapy targeting misfolded proteins in neurodegenerative disease].
Kazutomi Kanemaru
Brain Nerve 2013 Apr; 65(4):469-74
PMID: Object id #325923568995 [PubMed - as supplied by publisher]

Lewy body pathology is associated with mitochondrial DNA damage in Parkinson's disease.
Sarina K Müller, Andreas Bender, Christoph Laub, Tobias Högen, Falk Schlaudraff, Birgit Liss, Thomas Klopstock, Matthias Elstner
Neurobiol Aging 2013 Apr;
PMID: Object id #330223566333 [PubMed - as supplied by publisher]

Anti-Parkinson's disease drugs and pharmacogenetic considerations.
José A G Agúndez, Elena García-Martín, Hortensia Alonso-Navarro, Félix Javier Jiménez-Jiménez
Expert Opin Drug Metab Toxicol 2013 Apr;
PMID: Object id #333223565891 [PubMed - as supplied by publisher]

Genotype and age at Parkinson disease diagnosis.
Susan Searles Nielsen, Theo K Bammler, Lisa G Gallagher, Federico M Farin, Wt Longstreth, Gary M Franklin, Phillip D Swanson, Harvey Checkoway
Int J Mol Epidemiol Genet 2013 ; 4(1):61-9
PMID: Object id #335523565323 [PubMed - as supplied by publisher]

Effect of human interleukin-10 on the expression of nitric oxide synthases in the MPTP-based model of Parkinson's disease.
Joanna Schwenkgrub, Ilona Joniec-Maciejak, Anna Sznejder-Pacho?ek, Adriana Wawer, Agnieszka Ciesielska, Krzysztof Bankiewicz, Anna Cz?onkowska, Andrzej Cz?onkowski
Pharmacol Rep 2013 ; 65(1):44-9
PMID: Object id #342823563022 [PubMed - as supplied by publisher]

Comprehensive Characterization and Optimization of Leucine Rich Repeat Kinase 2 (LRRK2) Monoclonal Antibodies.
Paul Davies, Kelly M Hinkle, Nour N Sukar, Bryan Sepulveda, Roxana Mesias, Geidy Serrano, Dario R Alessi, Thomas G Beach, Deanna L Benson, Charles L White Iii, Rita M Cowell, Sonal S Das, Andrew B West, Heather L Melrose
Biochem J 2013 Apr;
PMID: Object id #351523560750 [PubMed - as supplied by publisher]

Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function.
Adam W Oaks, Maya Frankfurt, David I Finkelstein, Anita Sidhu
PLoS One 2013 ; 8(4):e60378
PMID: Object id #355423560093 [PubMed - as supplied by publisher]