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Sheng-Han Kuo, M.D.

“The PDF Côté Award [in Clinical Genetics] helped me to start my research.”

Sheng-Han Kuo, M.D.

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Causes and Pathology

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Behavioural impact of a double dopaminergic and serotonergic lesion in the non-human primate.
Maude Beaudoin-Gobert, Justine Epinat, Elise Météreau, Sandra Duperrier, Sara Neumane, Bénédicte Ballanger, Franck Lavenne, François Liger, Christian Tourvielle, Frédéric Bonnefoi, Nicolas Costes, Didier Le Bars, Emmanuel Broussolle, Stéphane Thobois, Léon Tremblay, Véronique Sgambato-Faure
Brain 2015 Jun;
PMID: 26117365 [PubMed - as supplied by publisher]

Transduced PEP-1-PON1 proteins regulate microglial activation and dopaminergic neuronal death in a Parkinson's disease model.
Mi Jin Kim, Meeyoung Park, Dae Won Kim, Min Jea Shin, Ora Son, Hyo Sang Jo, Hyeon Ji Yeo, Su Bin Cho, Jung Hwan Park, Chi Hern Lee, Duk-Soo Kim, Oh-Shin Kwon, Joon Kim, Kyu Hyung Han, Jinseu Park, Won Sik Eum, Soo Young Choi
Biomaterials 2015 Jun; 64:45-56
PMID: 26117230 [PubMed - as supplied by publisher]

Intrastriatal injection of pre-formed mouse ?-synuclein fibrils into rats triggers ?-synuclein pathology and bilateral nigrostriatal degeneration.
Katrina L Paumier, Kelvin C Luk, Fredric P Manfredsson, Nicholas M Kanaan, Jack W Lipton, Timothy J Collier, Kathy Steece-Collier, Christopher J Kemp, Stephanie Celano, Emily Schulz, Ivette M Sandoval, Sheila Fleming, Elliott Dirr, Nicole K Polinski, John Q Trojanowski, Virginia M Lee, Caryl E Sortwell
Neurobiol Dis 2015 Jun; 82:185-199
PMID: 26093169 [PubMed - as supplied by publisher]

Current knowledge and pharmacological profile of berberine: An update.
Anil Kumar, Ekavali, Kanwaljit Chopra, Madhurima Mukherjee, Raghavender Pottabathini, Dinesh K Dhull
Eur J Pharmacol 2015 Jun; 761:288-297
PMID: 26092760 [PubMed - as supplied by publisher]

GPER1-mediated immunomodulation and neuroprotection in the myenteric plexus of a mouse model of Parkinson's disease.
Mélissa Côté, Mélanie Bourque, Andrée-Anne Poirier, Benoit Aubé, Marc Morissette, Thérèse Di Paolo, Denis Soulet
Neurobiol Dis 2015 Jun; 82:99-113
PMID: 26051538 [PubMed - as supplied by publisher]

A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/-) mice.
Jingzhong Zhang, Sebastian Götz, Daniela M Vogt Weisenhorn, Antonio Simeone, Wolfgang Wurst, Nilima Prakash
Neurobiol Dis 2015 Jun; 82:32-45
PMID: 26049140 [PubMed - as supplied by publisher]

An in vitro model for synaptic loss in neurodegenerative diseases suggests a neuroprotective role for valproic acid via inhibition of cPLA2 dependent signalling.
Robin S B Williams, Clive Bate
Neuropharmacology 2015 Jun;
PMID: 26116815 [PubMed - as supplied by publisher]

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
Agne Kazlauskaite, R Julio Martínez-Torres, Scott Wilkie, Atul Kumar, Julien Peltier, Alba Gonzalez, Clare Johnson, Jinwei Zhang, Anthony G Hope, Mark Peggie, Matthias Trost, Daan Mf van Aalten, Dario R Alessi, Alan R Prescott, Axel Knebel, Helen Walden, Miratul Mk Muqit
EMBO Rep 2015 Jun;
PMID: 26116755 [PubMed - as supplied by publisher]

Tanshinone IIA protects dopaminergic neurons against 6-OHDA induced neurotoxicity through miR-153/Nrf2/ARE signaling pathway.
X S Zhang, S Ha, X L Wang, Y L Shi, S S Duan, Z A Li
Neuroscience 2015 Jun;
PMID: 26116522 [PubMed - as supplied by publisher]

?-Synuclein in Parkinson's disease: getting to the core of the matter.
Robert A Hauser
Lancet Neurol 2015 Jun;
PMID: 26116313 [PubMed - as supplied by publisher]

Ginsenoside Rd Protects SH-SY5Y Cells against 1-Methyl-4-phenylpyridinium Induced Injury.
Yang Liu, Ren-Yu Zhang, Jun Zhao, Zheng Dong, Dong-Yun Feng, Rui Wu, Ming Shi, Gang Zhao
Int J Mol Sci 2015 ; 16(7):14395-408
PMID: 26114390 [PubMed - as supplied by publisher]

Targeted Overexpression of ?-Synuclein by rAAV2/1 Vectors Induces Progressive Nigrostriatal Degeneration and Increases Vulnerability to MPTP in Mouse.
Lian-Kun Song, Kai-Li Ma, Yu-He Yuan, Zheng Mu, Xiu-Yun Song, Fei Niu, Ning Han, Nai-Hong Chen
PLoS One 2015; 10(6):e0131281
PMID: 26114655 [PubMed - as supplied by publisher]

Mitochondrial Dysfunction in Parkinson's Disease.
Hyo Eun Moon, Sun Ha Paek
Exp Neurobiol 2015 Jun; 24(2):103-16
PMID: 26113789 [PubMed - as supplied by publisher]

The initial stage of reversal learning is impaired in mice hemizygous for the vesicular glutamate transporter VGluT1.
Björn Granseth, Fredrik K Andersson, Sarah H Lindström
Genes Brain Behav 2015 Jun;
PMID: 26113146 [PubMed - as supplied by publisher]

Early use of oleanolic acid provides protection against 6-hydroxydopamine induced dopamine neurodegeneration.
Musa V Mabandla, Mpumelelo Nyoka, Willie M U Daniels
Brain Res 2015 Jun;
PMID: 26111646 [PubMed - as supplied by publisher]

Altered protein expression pattern in skin fibroblasts from parkin-mutant early-onset Parkinson's disease patients.
Rosa Lippolis, Rosa Anna Siciliano, Consiglia Pacelli, Anna Ferretta, Maria Fiorella Mazzeo, Salvatore Scacco, Francesco Papa, Antonio Gaballo, Claudia Dell'Aquila, Michele De Mari, Sergio Papa, Tiziana Cocco
Biochim Biophys Acta 2015 Jun;
PMID: 26096686 [PubMed - as supplied by publisher]

I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3? signaling pathway.
Etsuro Ohta, Tomoko Nihira, Akiko Uchino, Yoichi Imaizumi, Yohei Okada, Wado Akamatsu, Kayoko Takahashi, Hideki Hayakawa, Makiko Nagai, Manabu Ohyama, Masafuchi Ryo, Mieko Ogino, Shigeo Murayama, Akihiko Takashima, Kazutoshi Nishiyama, Yoshikuni Mizuno, Hideki Mochizuki, Fumiya Obata, Hideyuki Okano
Hum Mol Genet 2015 Jun;
PMID: 26056228 [PubMed - as supplied by publisher]

?-Synuclein and Lewy pathology in Parkinson's disease.
Lorraine V Kalia, Suneil K Kalia
Curr Opin Neurol 2015 Jun;
PMID: 26110807 [PubMed - as supplied by publisher]

Younger age at onset of sporadic Parkinson's disease among subjects occupationally exposed to metals and pesticides.
Marcia H Ratner, David H Farb, Josef Ozer, Robert G Feldman, Raymon Durso
Interdiscip Toxicol 2014 Sep; 7(3):123-33
PMID: 26109889 [PubMed - as supplied by publisher]

Structural and functional imaging study in dementia with Lewy bodies and Parkinson's disease dementia.
Barbara Borroni, Enrico Premi, Anna Formenti, Rosanna Turrone, Antonella Alberici, Elisabetta Cottini, Cristina Rizzetti, Roberto Gasparotti, Alessandro Padovani
Parkinsonism Relat Disord 2015 Jun;
PMID: 26109553 [PubMed - as supplied by publisher]

Inhibition of Calpain Activation Protects MPTP-Induced Nigral and Spinal Cord Neurodegeneration, Reduces Inflammation, and Improves Gait Dynamics in Mice.
Supriti Samantaray, Varduhi H Knaryan, Donald C Shields, April A Cox, Azizul Haque, Naren L Banik
Mol Neurobiol 2015 Jun;
PMID: 26108182 [PubMed - as supplied by publisher]

Limitations of in vivo reprogramming to dopaminergic neurons via a tricistronic strategy.
Marina Theodorou, Benedict Rauser, Jingzhong Zhang, Nilima Prakash, Wolfgang Wurst, Joel A Schick
Hum Gene Ther Methods 2015 Jun;
PMID: 26107288 [PubMed - as supplied by publisher]

Deep brain stimulation of the subthalamic nucleus preferentially alters the translational profile of striatopallidal neurons in an animal model of Parkinson's disease.
Naomi P Visanji, Iman Kamali Sarvestani, Meaghan C Creed, Zahra Shams Shoaei, José N Nobrega, Clement Hamani, Lili-Naz Hazrati
Front Cell Neurosci 2015 ; 9:221
PMID: 26106299 [PubMed - as supplied by publisher]

Optogenetic probing of mitochondrial damage responses.
Wei Yuan Yang
Ann N Y Acad Sci 2015 Jun;
PMID: 26104771 [PubMed - as supplied by publisher]

Glucocerebrosidase deficiency and mitochondrial impairment in experimental Parkinson disease.
Carmen Noelker, Lixia Lu, Matthias Höllerhage, Franca Vulinovic, Annekathrin Sturn, René Roscher, Günter U Höglinger, Etienne C Hirsch, Wolfgang H Oertel, Daniel Alvarez-Fischer, Hartmann Andreas
J Neurol Sci 2015 Jun;
PMID: 26104567 [PubMed - as supplied by publisher]

Inhibition of amyloid-? plaque formation by ?-synuclein.
Teresa Bachhuber, Natalie Katzmarski, Joanna F McCarter, Desiree Loreth, Sabina Tahirovic, Frits Kamp, Claudia Abou-Ajram, Brigitte Nuscher, Alberto Serrano-Pozo, Alexandra Müller, Marco Prinz, Harald Steiner, Bradley T Hyman, Christian Haass, Melanie Meyer-Luehmann
Nat Med 2015 Jun;
PMID: 26099047 [PubMed - as supplied by publisher]

Low Levels of Astroglial Markers in Parkinson's Disease: Relationship to ?-Synuclein Accumulation.
Junchao Tong, Lee-Cyn Ang, Belinda Williams, Yoshiaki Furukawa, Paul Fitzmaurice, Mark Guttman, Isabelle Boileau, Oleh Hornykiewicz, Stephen J Kish
Neurobiol Dis 2015 Jun;
PMID: 26102022 [PubMed - as supplied by publisher]

Neuroprotective effect of combined therapy with hyperbaric oxygen and madopar on 6-hydroxydopamine-induced Parkinson's disease in rats.
Xiaorong Pan, Chunxia Chen, Jianping Huang, Haiming Wei, Qiuping Fan
Neurosci Lett 2015 Jun;
PMID: 26101828 [PubMed - as supplied by publisher]

Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy.
Cathrin Meissner, Holger Lorenz, Beate Hehn, Marius K Lemberg
Autophagy 2015 Jun; :0
PMID: 26101826 [PubMed - as supplied by publisher]

Splicing variants of porcine synphilin-1.
Knud Larsen, Lone Bruhn Madsen, Leila Farajzadeh, Christian Bendixen
Meta Gene 2015 Sep; 5:32-42
PMID: 26101749 [PubMed - as supplied by publisher]

Can we use peripheral tissue biopsies to diagnose Parkinson's disease? A review of the literature.
S A Schneider, M Boettner, A Alexoudi, D Zorenkov, G Deuschl, T Wedel
Eur J Neurol 2015 Jun;
PMID: 26100920 [PubMed - as supplied by publisher]

Nigral overexpression of alpha-synuclein in the absence of parkin enhances alpha-synuclein phosphorylation but does not modulate dopaminergic neurodegeneration.
Anne-Sophie Van Rompuy, Marusela Oliveras-Salvá, Anke Van der Perren, Olga Corti, Chris Van den Haute, Veerle Baekelandt
Mol Neurodegener 2015 ; 10(1):23
PMID: 26099628 [PubMed - as supplied by publisher]

Association of the COQ2 V393A Variant with Parkinson's Disease: A Case-Control Study and Meta-Analysis.
Xinglong Yang, Jing Xi, Quanzhen Zhao, Hua Jia, Ran An, Zhuolin Liu, Yanming Xu
PLoS One 2015 ; 10(6):e0130970
PMID: 26098829 [PubMed - as supplied by publisher]

Oculo-visual changes and clinical considerations affecting older patients with dementia.
Richard Armstrong, Hélène Kergoat
Ophthalmic Physiol Opt 2015 Jul; 35(4):352-76
PMID: 26094831 [PubMed - as supplied by publisher]

The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases.
Cristina Carvalho, Sónia C Correia, Susana Cardoso, Ana I Plácido, Emanuel Candeias, Ana I Duarte, Paula I Moreira
Expert Rev Neurother 2015 Jun; :1-18
PMID: 26092668 [PubMed - as supplied by publisher]

Current treatment and future prospects of dopa-induced dyskinesias.
S Mazzucchi, D Frosini, U Bonuccelli, R Ceravolo
Drugs Today (Barc) 2015 May; 51(5):315-29
PMID: 26097904 [PubMed - as supplied by publisher]

The roles of redox enzymes in Parkinson's disease: Focus on glutaredoxin.
William M Johnson, Amy L Wilson-Delfosse, Shu G Chen, John J Mieyal
Ther Targets Neurol Dis 2015; 2(2)
PMID: 26097894 [PubMed - as supplied by publisher]

No evidence for substrate accumulation in Parkinson brains with GBA mutations.
Matthew E Gegg, Lindsay Sweet, Bing H Wang, Lamya S Shihabuddin, Sergio Pablo Sardi, Anthony H V Schapira
Mov Disord 2015 Jun;
PMID: 26096906 [PubMed - as supplied by publisher]

Localization of nuclear receptor subfamily 4, group A, member 3 (NR4A3) in Lewy body disease and multiple system atrophy.
Tomoya Kon, Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Masahiko Tomiyama, Yasuko Toyoshima, Akiyoshi Kakita, Hitoshi Takahashi, Jun Utsumi, Hidenao Sasaki, Koichi Wakabayashi
Neuropathology 2015 Jun;
PMID: 26096603 [PubMed - as supplied by publisher]

Correlates of excessive daytime sleepiness in de novo Parkinson's disease: A case control study.
Tanya Simuni, Chelsea Caspell-Garcia, Christopher Coffey, Lama M Chahine, Shirley Lasch, Wolfgang H Oertel, Geert Mayer, Birgit Högl, Ron Postuma, Aleksandar Videnovic, Amy Willis Amara, Ken Marek,
Mov Disord 2015 Jun;
PMID: 26095202 [PubMed - as supplied by publisher]

2, 2'- and 4, 4'- cyanines are transporter-independent in vitro dopaminergic toxins with the specificity and mechanism of toxicity similar to MPP.
Chamila C Kadigamuwa, Viet Q Le, Kandatege Wimalasena
J Neurochem 2015 Jun;
PMID: 26094622 [PubMed - as supplied by publisher]

Chronic pharmacological glucocerebrosidase inhibition induces ?-synuclein aggregation, microglial and complement activation and synaptic protein changes in mice.
Emily M Rocha, Gaynor A Smith, Eric Park, Hongmei Cao, Anne-Renee Graham, Eilish Brown, Jesse R McLean, Melissa A Hayes, Jonathan Beagan, Sarah C Izen, Eduardo Perez-Torres, Penelope J Hallett, Ole Isacson
Antioxid Redox Signal 2015 Jun;
PMID: 26094487 [PubMed - as supplied by publisher]

l-Dopa induced dyskinesias in Parkinsonian mice: Disease severity or l-Dopa history.
Lufei Shan, Oscar Diaz, Yajun Zhang, Bruce Ladenheim, Jean-Lud Cadet, Yung-Hsiao Chiang, Lars Olson, Barry J Hoffer, Cristina M Bäckman
Brain Res 2015 Jun;
PMID: 26086365 [PubMed - as supplied by publisher]

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study.
Niels Kruse, Staffan Persson, Daniel Alcolea, Justyna M C Bahl, Ines Baldeiras, Elisabetta Capello, Davide Chiasserini, Luisella Bocchio Chiavetto, Andreja Emersic, Sebastiaan Engelborghs, Erden Eren, Tormod Fladby, Giovanni Frisoni, María-Salud García-Ayllón, Sermin Genc, Olymbia Gkatzima, Niels H H Heegaard, André M Janeiro, Branislav Ková?ech, H Bea Kuiperij, Maria J Leitão, Alberto Lleó, Madalena Martins, Mafalda Matos, Hanne M Mollergard, Flavio Nobili, Annika Öhrfelt, Lucilla Parnetti, Catarina Resende de Oliveira, Uros Rot, Javier Sáez-Valero, Hanne Struyfs, Julia T Tanassi, Peggy Taylor, Magda Tsolaki, Eugeen Vanmechelen, Marcel M Verbeek, Norbert Zilka, Kaj Blennow, Henrik Zetterberg, Brit Mollenhauer
Neurobiol Aging 2015 May;
PMID: 26093515 [PubMed - as supplied by publisher]

The novel mitochondrial iron chelator 5-((methylamino)methyl)-8-hydroxyquinoline protects against mitochondrial-induced oxidative damage and neuronal death.
Natalia P Mena, Olimpo García-Beltrán, Fernanda Lourido, Pamela J Urrutia, Raúl Mena, Vicente Castro-Castillo, Bruce K Cassels, Marco T Núñez
Biochem Biophys Res Commun 2015 Jun;
PMID: 26051278 [PubMed - as supplied by publisher]

Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity.
Sorabh Sharma, Rajeev Taliyan, Sumel Singh
Behav Brain Res 2015 Jun; 291:306-314
PMID: 26048426 [PubMed - as supplied by publisher]

Understanding the Influence of Parkinson's Disease on Adolf Hitler's Decision-Making during World War II.
Raghav Gupta, Christopher Kim, Nitin Agarwal, Bryan Lieber, Edward A Monaco
World Neurosurg 2015 Jun;
PMID: 26093359 [PubMed - as supplied by publisher]

Tea Polyphenols in Parkinson's Disease.
Mario Caruana, Neville Vassallo
Adv Exp Med Biol 2015 ; 863:117-37
PMID: 26092629 [PubMed - as supplied by publisher]

Deregulation of protein translation control, a potential game-changing hypothesis for Parkinson's disease pathogenesis.
Jean-Marc Taymans, Aurore Nkiliza, Marie-Christine Chartier-Harlin
Trends Mol Med 2015 Jun;
PMID: 26091824 [PubMed - as supplied by publisher]

Parkinson's Disease and Home Healthcare Use and Expenditures among Elderly Medicare Beneficiaries.
Sandipan Bhattacharjee, Aaron Metzger, Cindy Tworek, Wenhui Wei, Xiaoyun Pan, Usha Sambamoorthi
Parkinsons Dis 2015 ; 2015:606810
PMID: 26090265 [PubMed - as supplied by publisher]

(123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review.
Eun Joo Chung, Sang Jin Kim
J Mov Disord 2015 May; 8(2):55-66
PMID: 26090077 [PubMed - as supplied by publisher]

Aging-related rotenone-induced neurochemical and behavioral deficits: role of SIRT2 and redox imbalance, and neuroprotection by AK-7.
Xijin Wang, Qiang Guan, Meihua Wang, Liu Yang, Jie Bai, Zhiqiang Yan, Yuhong Zhang, Zhenguo Liu
Drug Des Devel Ther 2015 ; 9:2553-63
PMID: 26089639 [PubMed - as supplied by publisher]

Allicin Protects PC12 Cells Against 6-OHDA-Induced Oxidative Stress and Mitochondrial Dysfunction via Regulating Mitochondrial Dynamics.
Hao Liu, Ping Mao, Jia Wang, Tuo Wang, Chang-Hou Xie
Cell Physiol Biochem 2015 Jun; 36(3):966-979
PMID: 26087780 [PubMed - as supplied by publisher]

Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson's Disease.
Anke A Dijkstra, Angela Ingrassia, Renee X de Menezes, Ronald E van Kesteren, Annemieke J M Rozemuller, Peter Heutink, Wilma D J van de Berg
PLoS One 2015 ; 10(6):e0128651
PMID: 26087293 [PubMed - as supplied by publisher]

Selective damage to dopaminergic transporters following exposure to the brominated flame retardant, HBCDD.
Kelly R Genskow, Joshua M Bradner, Muhammad M Hossain, Jason R Richardson, W Michael Caudle
Neurotoxicol Teratol 2015 Jun;
PMID: 26073293 [PubMed - as supplied by publisher]

Characterization of the lipopolysaccharide induced model of Parkinson's disease: Role of oxidative stress and neuroinflammation.
Neha Sharma, Bimla Nehru
Neurochem Int 2015 Jun;
PMID: 26055970 [PubMed - as supplied by publisher]

Melatonin:- A potential antioxidant therapeutic agent for mitochondrial dysfunctions and related disorders.
Showkat Ahmad Ganie, Tanveer Dar, Aashiq Bhat, Khalid Dar, Suhail Anees, Akbar Masood, Mohammad Afzal Zargar
Rejuvenation Res 2015 Jun;
PMID: 26087000 [PubMed - as supplied by publisher]

Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis.
Myungjin Kim, Ian Semple, Boyoung Kim, Alexandra Kiers, Samuel Nam, Hwan-Woo Park, Haeli Park, Seung-Hyun Ro, Jeong-Sig Kim, Gábor Juhász, Jun Hee Lee
Autophagy 2015 Jun; :0
PMID: 26086452 [PubMed - as supplied by publisher]

Intraventricular cerebrospinal fluid temperature analysis using MR diffusion-weighted imaging thermometry in Parkinson's disease patients, multiple system atrophy patients, and healthy subjects.
Kaoru Sumida, Noriko Sato, Miho Ota, Koji Sakai, Yasumasa Nippashi, Daichi Sone, Kota Yokoyama, Kimiteru Ito, Norihide Maikusa, Etsuko Imabayashi, Hiroshi Matsuda, Kei Yamada, Miho Murata, Akira Kunimatsu, Kuni Ohtomo
Brain Behav 2015 Jun; 5(6):e00340
PMID: 26085965 [PubMed - as supplied by publisher]

Wnt3a protects SH-SY5Y cells against 6-hydroxydopamine toxicity by restoration of mitochondria function.
Lei Wei, Li Ding, Ming-Shu Mo, Ming Lei, Limin Zhang, Kang Chen, Pingyi Xu
Transl Neurodegener 2015 ; 4:11
PMID: 26085927 [PubMed - as supplied by publisher]

Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis.
Chris Stinton, Ian McKeith, John-Paul Taylor, Louise Lafortune, Eneida Mioshi, Elijah Mak, Victoria Cambridge, James Mason, Alan Thomas, John T O'Brien
Am J Psychiatry 2015 Jun; :appiajp201514121582
PMID: 26085043 [PubMed - as supplied by publisher]

Lipoic acid protects dopaminergic neurons in LPS-induced Parkinson's disease model.
Yan-Hua Li, Qing He, Jie-Zhong Yu, Chun-Yun Liu, Ling Feng, Zhi Chai, Qing Wang, Hong-Zhen Zhang, Guang-Xian Zhang, Bao-Guo Xiao, Cun-Gen Ma
Metab Brain Dis 2015 Jun;
PMID: 26084861 [PubMed - as supplied by publisher]

Alpha-synuclein A53T mutation is not frequent on a sample of Brazilian Parkinson's disease patients.
Gabriela S Longo, Marcela A S Pinhel, Michele L Gregório, Bruno A P Oliveira, Driele C G Quinhoneiro, Waldir A Tognola, Fábio N Oliveira, Sabrina M Cezario, Caroline L Sado, Marcelo A Nakazone, Maria C J Calastri, Dorotéia R S Souza
Arq Neuropsiquiatr 2015 Jun; 73(6):506-9
PMID: 26083886 [PubMed - as supplied by publisher]

?-Synuclein strains cause distinct synucleinopathies after local and systemic administration.
W Peelaerts, L Bousset, A Van der Perren, A Moskalyuk, R Pulizzi, M Giugliano, C Van den Haute, R Melki, V Baekelandt
Nature 2015 Jun; 522(7556):340-4
PMID: 26061766 [PubMed - as supplied by publisher]

Association of Polymorphism of Neuronal Nitric Oxide Synthase Gene with Risk to Parkinson's Disease.
Satya Prakash Gupta, Ritul Kamal, Sarad Kumar Mishra, Maneesh Kumar Singh, Rakesh Shukla, Mahendra Pratap Singh
Mol Neurobiol 2015 Jun;
PMID: 26081147 [PubMed - as supplied by publisher]

Medial temporal regional argyrophilic grain as a possible important factor affecting dementia in Parkinson's disease.
Taku Homma, Yoko Mochizuki, Kazushi Takahashi, Takashi Komori
Neuropathology 2015 Jun;
PMID: 26079638 [PubMed - as supplied by publisher]

Gastrointestinal Biopsies for the Diagnosis of Alpha-Synuclein Pathology in Parkinson's Disease.
Maria Graciela Cersosimo
Gastroenterol Res Pract 2015 ; 2015:476041
PMID: 26078752 [PubMed - as supplied by publisher]

LRRK2 Pharmacological Inhibition Abates ?-Synuclein Induced Neurodegeneration.
João P L Daher, Hisham A Abdelmotilib, Xianzhen Hu, Laura A Volpicelli-Daley, Mark S Moehle, Kyle B Faser, Elie Needle, Yi Chen, Stefanus J Steyn, Paul Galatsis, Warren D Hirst, Andrew B West
J Biol Chem 2015 Jun;
PMID: 26078453 [PubMed - as supplied by publisher]

Olfactory function and neuropsychological profile to differentiate dementia with Lewy bodies from Alzheimer's disease in patients with mild cognitive impairment: A 5-year follow-up study.
Jung Han Yoon, Min Kim, So Young Moon, Seok Woo Yong, Ji Man Hong
J Neurol Sci 2015 Jun;
PMID: 26076880 [PubMed - as supplied by publisher]

Parkinson-causing ?-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation.
Ulf Dettmer, Andrew J Newman, Frank Soldner, Eric S Luth, Nora C Kim, Victoria E von Saucken, John B Sanderson, Rudolf Jaenisch, Tim Bartels, Dennis Selkoe
Nat Commun 2015 ; 6:7314
PMID: 26076669 [PubMed - as supplied by publisher]

Dopaminergic Neurons Respond to Iron-Induced Oxidative Stress by Modulating Lipid Acylation and Deacylation Cycles.
Sofía Sánchez Campos, Guadalupe Rodríguez Diez, Gerardo Martín Oresti, Gabriela Alejandra Salvador
PLoS One 2015 ; 10(6):e0130726
PMID: 26076361 [PubMed - as supplied by publisher]

R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study.
Olena Korvatska, James B Leverenz, Suman Jayadev, Pamela McMillan, Irina Kurtz, Xindi Guo, Malia Rumbaugh, Mark Matsushita, Santhosh Girirajan, Michael O Dorschner, Kostantin Kiianitsa, Chang-En Yu, Zoran Brkanac, Gwenn A Garden, Wendy H Raskind, Thomas D Bird
JAMA Neurol 2015 Jun;
PMID: 26076170 [PubMed - as supplied by publisher]

shRNA targeting ?-synuclein prevents neurodegeneration in a Parkinson's disease model.
Alevtina D Zharikov, Jason R Cannon, Victor Tapias, Qing Bai, Max P Horowitz, Vipul Shah, Amina El Ayadi, Teresa G Hastings, J Timothy Greenamyre, Edward A Burton
J Clin Invest 2015 Jun;
PMID: 26075822 [PubMed - as supplied by publisher]

Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells.
Begum Alural, Aysegul Ozerdem, Jens Allmer, Kursad Genc, Sermin Genc
Front Cell Neurosci 2015 ; 9:209
PMID: 26074776 [PubMed - as supplied by publisher]

Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy: A paradigm for axonal degeneration.
Stéphane Fourcade, Isidre Ferrer, Aurora Pujol
Free Radic Biol Med 2015 Jun;
PMID: 26073123 [PubMed - as supplied by publisher]

Characterization of retinal architecture in Parkinson's disease.
Jessica Chorostecki, Navid Seraji-Bozorgzad, Aashka Shah, Fen Bao, Ginny Bao, Edwin George, Veronica Gorden, Christina Caon, Elliot Frohman, M Tariq Bhatti, Omar Khan
J Neurol Sci 2015 May;
PMID: 26071887 [PubMed - as supplied by publisher]

Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo.
Hyung-Wook Kim, Won-Seok Choi, Noah Sorscher, Hyung Joon Park, François Tronche, Richard D Palmiter, Zhengui Xia
Neurobiol Aging 2015 May;
PMID: 26070241 [PubMed - as supplied by publisher]

Total and Proteinase K-Resistant ?-Synuclein Levels in Erythrocytes, Determined by their Ability to Bind Phospholipids, Associate with Parkinson's Disease.
Suaad Abd-Elhadi, Asaf Honig, Dganit Simhi-Haham, Meir Schechter, Eduard Linetsky, Tamir Ben-Hur, Ronit Sharon
Sci Rep 2015 ; 5:11120
PMID: 26068055 [PubMed - as supplied by publisher]

Ginsenoside Rg1 Ameliorates Motor Function in an Animal Model of Parkinson's Disease.
Wenda Jiang, Zhejian Wang, Yiyang Jiang, Meili Lu, Xin Li
Pharmacology 2015 Jun; 96(1-2):25-31
PMID: 26065578 [PubMed - as supplied by publisher]

Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds.
Saif Khan, Khurshid Ahmad, Eyad M A Alshammari, Mohd Adnan, Mohd Hassan Baig, Mohtashim Lohani, Pallavi Somvanshi, Shafiul Haque
Biomed Res Int 2015 ; 2015:379817
PMID: 26064904 [PubMed - as supplied by publisher]

Visual Hallucinations as Incidental Negative Effects of Virtual Reality on Parkinson's Disease Patients: A Link with Neurodegeneration?
Giovanni Albani, Elisa Pedroli, Pietro Cipresso, Daniel Bulla, Veronica Cimolin, Astrid Thomas, Alessandro Mauro, Giuseppe Riva
Parkinsons Dis 2015 ; 2015:194629
PMID: 26064775 [PubMed - as supplied by publisher]

Mitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's Diseases.
Carlos Fernández-Moriano, Elena González-Burgos, M Pilar Gómez-Serranillos
Oxid Med Cell Longev 2015; 2015:408927
PMID: 26064418 [PubMed - as supplied by publisher]

Ranitidine reduced levodopa-induced dyskinesia by remodeling neurochemical changes in hemiparkinsonian model of rats.
Hongjuan Shi, Xinxin Yang, Hui Zhao, Shenyang Zhang, Jie Zu, Wei Zhang, Xia Shen, Guiyun Cui, Fang Hua, Chuanzhu Yan
Neuropsychiatr Dis Treat 2015 ; 11:1331-7
PMID: 26064051 [PubMed - as supplied by publisher]

Ferulic acid and Alzheimer's disease: promises and pitfalls.
Seyed Fazel Nabavi, Kasi Pandima Devi, Dicson Sheeja Malar, Antoni Sureda, Maria Daglia, Seyed Mohammad Nabavi
Mini Rev Med Chem 2015 Jun;
PMID: 26063498 [PubMed - as supplied by publisher]

Age-specific penetrance of LRRK2 G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 Consortium.
Karen Marder, Yuanjia Wang, Roy N Alcalay, Helen Mejia-Santana, Ming-Xin Tang, Annie Lee, Deborah Raymond, Anat Mirelman, Rachel Saunders-Pullman, Lorraine Clark, Laurie Ozelius, Avi Orr-Urtreger, Nir Giladi, Susan Bressman,
Neurology 2015 Jun;
PMID: 26062626 [PubMed - as supplied by publisher]

Head injury, ?-synuclein Rep1 and Parkinson's disease: a meta-analytic view of gene-environment interaction.
S M Goldman, D M Umbach, F Kamel, C M Tanner
Eur J Neurol 2015 Jul; 22(7):e75
PMID: 26060929 [PubMed - as supplied by publisher]

Drug-induced Skin Lesions in Cynomolgus Macaques Treated with Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulators.
Gopinath S Palanisamy, John M Marcek, Gregg D Cappon, Jessica Whritenour, Christopher L Shaffer, Joseph T Brady, Christopher Houle
Toxicol Pathol 2015 Jun;
PMID: 26059827 [PubMed - as supplied by publisher]

Cannabinoid-dopamine interactions in the physiology and physiopathology of the basal ganglia.
Concepción García, Cristina Palomo-Garo, Yolanda Gómez-Gálvez, Javier Fernández-Ruiz
Br J Pharmacol 2015 Jun;
PMID: 26059564 [PubMed - as supplied by publisher]

Splitting up the powerhouse: structural insights into the mechanism of mitochondrial fission.
Viviane Richter, Abeer P Singh, Marc Kvansakul, Michael T Ryan, Laura D Osellame
Cell Mol Life Sci 2015 Jun;
PMID: 26059473 [PubMed - as supplied by publisher]

Interaction between Neuromelanin and Alpha-Synuclein in Parkinson's Disease.
Shengli Xu, Piu Chan
Biomolecules 2015 ; 5(2):1122-42
PMID: 26057626 [PubMed - as supplied by publisher]

Effects of methylmercury on dopamine release in MN9D neuronal cells.
Yueting Shao, Hing Man Chan
Toxicol Mech Methods 2015 Jun; :1-8
PMID: 26056851 [PubMed - as supplied by publisher]

Increased plasma levels of phospholipid in Parkinson's disease with mild cognitive impairment.
Zhenguang Li, Jinbiao Zhang, Hairong Sun
J Clin Neurosci 2015 Jun;
PMID: 26055959 [PubMed - as supplied by publisher]

Association between serum uric acid and motor subtypes of Parkinson's disease.
Praween Lolekha, Piyanat Wongwan, Kongkiat Kulkantrakorn
J Clin Neurosci 2015 Jun;
PMID: 26055955 [PubMed - as supplied by publisher]

?-Synuclein Shows High-Affinity Interaction with Voltage-Dependent Anion Channel Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease.
Tatiana K Rostovtseva, Philip A Gurnev, Olga Protchenko, David P Hoogerheide, Thai Leong Yap, Caroline C Philpott, Jennifer C Lee, Sergey M Bezrukov
J Biol Chem 2015 Jun;
PMID: 26055708 [PubMed - as supplied by publisher]

Randomized, double-blind, placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinson's disease.
Asako Yoritaka, Sumihiro Kawajiri, Yorihiro Yamamoto, Toshiki Nakahara, Maya Ando, Kazuhiko Hashimoto, Midori Nagase, Yufuko Saito, Nobutaka Hattori
Parkinsonism Relat Disord 2015 May;
PMID: 26054881 [PubMed - as supplied by publisher]

Effects of electroacupuncture on proteasomes of substantia nigra in rats with Parkinson's disease].
Qian Tu, Yan Liang, Jun Ma, Shuju Wang, Feng Shen, Yanchun Wang
Zhongguo Zhen Jiu 2015 Apr; 35(4):355-60
PMID: 26054145 [PubMed - as supplied by publisher]

The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration.
Jennifer M Deger, Julia E Gerson, Rakez Kayed
Aging Cell 2015 Jun;
PMID: 26053162 [PubMed - as supplied by publisher]

Vulnerability of synapses in the frontal cortex of mice developmentally exposed to an insecticide: Potential contribution to neuropsychiatric disease.
W Michael Caudle
Neurotransmitter (Houst) 2015; 2(1)
PMID: 26052547 [PubMed - as supplied by publisher]

Targeting ?-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations.
Benjamin Dehay, Mathieu Bourdenx, Philippe Gorry, Serge Przedborski, Miquel Vila, Stéphane Hunot, Andrew Singleton, C Warren Olanow, Kalpana M Merchant, Erwan Bezard, Gregory A Petsko, Wassilios G Meissner
Lancet Neurol 2015 Jun;
PMID: 26050140 [PubMed - as supplied by publisher]

Phytoestrogen ?-ecdysterone protects PC12 Cells against MPP+-induced neurotoxicity in vitro: Involvement of PI3K-Nrf2-regulated pathway.
Yu Zou, Rongtian Wang, Hongyan Guo, Miaoxian Dong
Toxicol Sci 2015 Jun;
PMID: 26048653 [PubMed - as supplied by publisher]