Adjust Text Size:change font sizechange font sizechange font sizechange font sizechange font sizechange font size

Kim and Libbe Erickson, R.N.

How can a research “dream team” — scientists and people living with PD — work together to more quickly solve, treat and end PD?

Learn More

PDF Grant Programs

Are you interested in furthering Parkinson's science? View PDF's open grant programs.

Learn More


Causes and Pathology

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.


Prevención de Caídas

1) PDF Research Centers

Columbia


http://www.ncbi.nlm.nih.gov/pubmed?term=Columbia%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(alcalay%20rn%5Bau%5D%20OR%20burke%20rb%5BAU%5D%20OR%20clark%20l%5BAU%5D%20OR%20fahn%20s%5BAU%5D%20OR%20Ford%20B%5BAU%5D%20OR%20greene%20l%5BAU%5D%20OR%20greene%20p%5BAU%5D%20OR%20kuo%20sh%5Bau%5D%20OR%20louis%20e%5BAU%5D%20OR%20marder%20k%5BAU%5D%20OR%20mazzoni%20p%5BAU%5D%20OR%20przedborski%20s%5BAU%5D%20OR%20pullman%20s%5BAU%5D%20OR%20stern%20y%5BAU%5D%20OR%20sulzer%20d%5BAU%5D%20OR%20vonsattel%5BAU%5D%20OR%20waters%20c%5BAU%5D%20OR%20yamamoto%20a%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Rush


http://www.ncbi.nlm.nih.gov/pubmed?term=Rush%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Barton%20B%5BAU%5D%20OR%20Bernard%20B%5BAU%5D%20OR%20Comella%20C%5BAU%5D%20OR%20Goldman%20J%5BAU%5D%20OR%20Goetz%20C%5BAU%5D%20OR%20Hall%20D%5BAU%5D%20OR%20Kompoliti%20K%5BAU%5D%20OR%20Kordower%20J%5BAU%5D%20OR%20Shannon%20K%5BAU%5D%20Stebbins%20G%5BAU%5D%20OR%20Verhagen%20L%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Cornell


http://www.ncbi.nlm.nih.gov/pubmed?term=Cornell%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Beal%20MF%5BAU%5D%20OR%20Henchcliffe%20c%5BAU%5D%20OR%20Nirenberg%20m%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

PARKINSON’S DISEASE TOPIC AREAS
Understanding Parkinson’s


Motor Symptoms
    

General

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(motor%5BAll%20Fields%5D%20AND%20(%22diagnosis%22%5BSubheading%5D%20OR%20%22diagnosis%22%5BAll%20Fields%5D%20OR%20%22symptoms%22%5BAll%20Fields%5D%20OR%20%22diagnosis%22%5BMeSH%20Terms%5D%20OR%20%22symptoms%22%5BAll%20Fields%5D))%20NOT%20(%E2%80%9Cnon-motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnon%20motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnonmotor%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)%20AND%20(%22review%22%5BPublication%20Type%5D%20OR%20%22review%20literature%20as%20topic%22%5BMeSH%20Terms%5D%20OR%20%22review%22%5BAll%20Fields%5D)

    Balance and Falls

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Balance%20%5BTIAB%5D%20OR%20Falls%20%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)
    Gait or Freezing

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Gait%5BTIAB%5D%20OR%20Freezing%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Dyskinesia
    Nonmotor Symptoms and Complications

    General
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(%E2%80%9Cnon-motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnon%20motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnonmotor%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Pain
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(pain%5BTI%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Sleep and Fatigue/ REM Behavior Sleep Disorder

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Sleep%5BTIAB%5D%20OR%20Fatigue%5BTIAB%5D%20OR%20%E2%80%9DREM%20behavior%20disorder%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Gastrointestinal and Urinary Function
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Gastrointestinal%5BTIAB%5D%20OR%20Urinary%20%5BTIAB%5D%20OR%20%E2%80%9CBowel%20dysfunction%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9CBladder%20dysfunction%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Cognition and Hallucination

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(cognition%5BTIAB%5D%20OR%20hallucination%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Impulse Control Disorder

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Impulse%20Control%20Disorder%5BTIAB%5D%20OR%20ICD%5BTIAB%5D%20OR%20gambling%5BTIAB%5D%20OR%20shopping%5BTIAB%5D%20OR%20hypersexuality%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Vision/Visual hallucination

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Blurred%20vision%5BTIAB%5D%20OR%20Photophobia%5BTIAB%5D%20OR%20Asthenopia%5BTIAB%5D%20OR%20Double%20vision%5BTIAB%5D%20OR%20Visual%20hallucination%5BTIAB%5D%20OR%20spatial%20relations%5BTIAB%5D%20OR%20color%20perception%5BTIAB%5D)

Oral
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(dental%5BTIAB%5D%20OR%20dysphagia%5BTIAB%5D%20OR%20burning%20mouth%5BTIAB%5D%20OR%20drooling%5BTIAB%5D%20OR%20teeth%5BTIAB%5D%20or%20sialorrhea%5BTIAB%5D%20OR%20gingiva%5BTIAB%5D%20OR%20periodontal%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Speech
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(speech%5BTIAB%5D%20OR%20hypophonia%5BTIAB%5D%20OR%20verbal%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Orthostatic Hypotension
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Orthostatic%20Hypotension%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Etiology/Pathology

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(etiology%5BTIAB%5D%20OR%20pathology%5BTIAB%5D%20OR%20disease%20model%5BTIAB%5D)%20AND%20(%22review%22%5BPublication%20Type%5D%20OR%20%22review%20literature%20as%20topic%22%5BMeSH%20Terms%5D%20OR%20%22review%22%5BAll%20Fields%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Imaging Studies
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(imaging%5BTIAB%5D%20OR%20MRI%5BTIAB%5D%20OR%20fMRI%5BTIAB%5D%20OR%20PET%5BTIAB%5D%20OR%20SPECT%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Clinical Studies

General
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20Clinical%20Trial%5Bptyp%5D%20AND%20(%22last%20180%20days%22%5BDP%5D)

Genetics

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(%22genetics%22%5BSubheading%5D%20OR%20%22genetics%22%5BAll%20Fields%5D%20OR%20%22genetics%22%5BMeSH%20Terms%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Treating Parkinson’s

Current and potential medications/Therapies http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(treatment%5BTI%5D%20OR%20therapy%5BTI%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Surgical Treatments
        
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(stem%20cell%5BTIAB%5D)%20AND%20(treatment%5BTIAB%5D%20OR%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)
    
Gene Therapy
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(gene%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Deep Brain Stimulation
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(gene%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Physical, Occupational and Speech Therapy
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(physical%20therapy%5BTIAB%5D%20OR%20occupational%20therapy%5BTIAB%5D%20OR%20speech%20therapy%5BTIAB%5D%20OR%20rehabilitation%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Nutrition

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(diet%5Btiab%5D%20OR%20nutrition%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Exercise
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(exercise%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Art and Music

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(art%5BTIAB%5D%20OR%20painting%5BTIAB%5D%20OR%20creativity%5BTIAB%5DOR%20music%5BTIAB%5D)%20NOT%20%E2%80%9Cstate%20of%20the%20art%E2%80%9D%5BTIAB%5D%20AND%20(%22last%2090%20days%22%5BDP%5D)


Complementary and Alternative Therapies
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(complementary%20therapy%5BTIAB%5D%20OR%20alternative%20therapy%5BTIAB%5D%20OR%20Adjunct%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Living with a Parkinson’s Diagnosis

Driving
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(driving%5BTIAB%5D%20AND%20(car%5BTIAB%5D%20OR%20automobile%5BTIAB%5D))

Hospitalization


http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(hospitalization%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Care giving
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(caregiver%5BTIAB%5D%20OR%20caregiving%5BTIAB%5D%20OR%20hygiene%5BTIAB%5D%20OR%20dressing%5BTIAB%5D%20OR%20support%20group%5BTIAB%5D%20OR%20health%20care%5BTIAB%5D%20OR%20home%20care%5BTIAB%5D%20OR%20helpline%5BTIAB%5D)AND%20(%22last%2090%20days%22%5BDP%5D)

Hospice/End of Life/Palliative Care
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(hospice%5BTI%5D%20OR%20%E2%80%9Cend%20of%20life%E2%80%9D%5BTI%5D%20OR%20palliative%5BTI%5D)

There was an error retrieving the document. Please try again.

Pharmacophore Model Prediction, 3D-QSAR and Molecular Docking studies on Vinyl Sulfones Targeting Nrf2-Mediated Gene Transcription intended for Anti-Parkinson Drug Design.
Mohd Athar, Mohsin Yousuf Lone, Vijay M Khedkar, Prakash Chandra Jha
J Biomol Struct Dyn 2015 Jul; :1-39
PMID: 26222438 [PubMed - as supplied by publisher]


Overexpression of DJ-1 protects against C2-ceramide-induced neuronal death through activation of the PI3K/AKT pathway and inhibition of autophagy.
Jenny Jaramillo-Gómez, Andrea Niño, Humberto Arboleda, Gonzalo Arboleda
Neurosci Lett 2015 Jul;
PMID: 26222260 [PubMed - as supplied by publisher]


The ubiquitin proteasome system as a potential therapeutic target for treatment of neurodegenerative diseases.
Alena Opattova, Martin Cente, Michal Novak, Peter Filipcik
Gen Physiol Biophys 2015 Jul;
PMID: 26221742 [PubMed - as supplied by publisher]


Cholinesterase Inhibitors for Lewy Body Disorders: A Meta-Analysis.
Shinji Matsunaga, Taro Kishi, Ichiro Yasue, Nakao Iwata
Int J Neuropsychopharmacol 2015 Jul;
PMID: 26221005 [PubMed - as supplied by publisher]


Association between ?-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease.
Joseph J Locascio, Shirley Eberly, Zhixiang Liao, Ganqiang Liu, Ashley N Hoesing, Karen Duong, Ana Trisini-Lipsanopoulos, Kaltra Dhima, Albert Y Hung, Alice W Flaherty, Michael A Schwarzschild, Michael T Hayes, Anne-Marie Wills, U Shivraj Sohur, Nicte I Mejia, Dennis J Selkoe, David Oakes, Ira Shoulson, Xianjun Dong, Ken Marek, Bin Zheng, Adrian Ivinson, Bradley T Hyman, John H Growdon, Lewis R Sudarsky, Michael G Schlossmacher, Bernard Ravina, Clemens R Scherzer
Brain 2015 Jul;
PMID: 26220939 [PubMed - as supplied by publisher]


The temporary and accumulated effects of transcranial direct current stimulation for the treatment of advanced Parkinson's disease monkeys.
Hao Li, Xiaoguang Lei, Ting Yan, Hongwei Li, Baihui Huang, Ling Li, Liqi Xu, Li Liu, Nanhui Chen, Longbao Lü, Yuanye Ma, Lin Xu, Jiali Li, Zhengbo Wang, Baorong Zhang, Xintian Hu
Sci Rep 2015 ; 5:12178
PMID: 26220760 [PubMed - as supplied by publisher]


LK6/Mnk2a is a new kinase of alpha synuclein phosphorylation mediating neurodegeneration.
Shiqing Zhang, Jiang Xie, Ying Xia, Shu Yu, Zhili Gu, Ruili Feng, Guanghong Luo, Dong Wang, Kai Wang, Meng Jiang, Xiao Cheng, Hai Huang, Wu Zhang, Tieqiao Wen
Sci Rep 2015 ; 5:12564
PMID: 26220523 [PubMed - as supplied by publisher]


Regulation of mitochondrial morphology and function by stearoylation of TFR1.
Deniz Senyilmaz, Sam Virtue, Xiaojun Xu, Chong Yew Tan, Julian L Griffin, Aubry K Miller, Antonio Vidal-Puig, Aurelio A Teleman
Nature 2015 Jul;
PMID: 26214738 [PubMed - as supplied by publisher]


Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies.
Mathieu Bourdenx, Nikolaos Stavros Koulakiotis, Despina Sanoudou, Erwan Bezard, Benjamin Dehay, Anthony Tsarbopoulos
Prog Neurobiol 2015 Jul;
PMID: 26209472 [PubMed - as supplied by publisher]


Cysteine cathepsins are essential in lysosomal degradation of ?-synuclein.
Ryan P McGlinchey, Jennifer C Lee
Proc Natl Acad Sci U S A 2015 Jul; 112(30):9322-7
PMID: 26170293 [PubMed - as supplied by publisher]


Oxidative stress and Parkinson's disease.
Javier Blesa, Ines Trigo-Damas, Anna Quiroga-Varela, Vernice R Jackson-Lewis
Front Neuroanat 2015 ; 9:91
PMID: 26217195 [PubMed - as supplied by publisher]


Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice.
Vera L Bonilha, Brent A Bell, Mary E Rayborn, Xiaoping Yang, Charlie Kaul, Gregory H Grossman, Ivy S Samuels, Joe G Hollyfield, Chengsong Xie, Huaibin Cai, Karen G Shadrach
Exp Eye Res 2015 Jul;
PMID: 26215528 [PubMed - as supplied by publisher]


Antimicrobial peptide, Lumbricusin, ameliorates motor dysfunction and dopaminergic neurodegeneration in a mouse model of Parkinson's disease.
Dae Hong Kim, Ik Hwan Lee, Seung Taek Nam, Ji Hong, Peng Zhang, Li Fang Lu, Jae Sam Hwang, Ki Cheol Park, Ho Kim
J Microbiol Biotechnol 2015 Jul;
PMID: 26215270 [PubMed - as supplied by publisher]


Transiently impaired neurogenesis in MPTP mouse model of Parkinson's disease.
Xi Jun He, Hiroyuki Nakayama
Neurotoxicology 2015 Jul;
PMID: 26215120 [PubMed - as supplied by publisher]


DEVELOPMENTAL EXPOSURE TO MANGANESE INDUCES LASTING MOTOR AND COGNITIVE IMPAIRMENT IN RATS.
Tanara V Peres, Helena Eyng, Samantha C Lopes, Dirleise Colle, Filipe M Gonçalves, Débora K R Venske, Mark W Lopes, Juliana Ben, Julia Bornhorst, Tanja Schwerdtle, Michael Aschner, Marcelo Farina, Rui D Prediger, Rodrigo B Leal
Neurotoxicology 2015 Jul;
PMID: 26215118 [PubMed - as supplied by publisher]


Neonatal chlorpyrifos exposure induces loss of dopaminergic neurons in young adult rats.
Jie Zhang, HongMei Dai, YuanYing Deng, Jing Tian, Chen Zhang, ZhiPing Hu, Guoying Bing, Lingling Zhao
Toxicology 2015 Jul;
PMID: 26215101 [PubMed - as supplied by publisher]


Did ?-Synuclein and Glucocerebrosidase Coevolve? Implications for Parkinson's Disease.
James M Gruschus
PLoS One 2015 ; 10(7):e0133863
PMID: 26214314 [PubMed - as supplied by publisher]


Direct and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein Toxicity.
Shamini Vijayakumaran, Mathew B Wong, Helma Antony, Dean L Pountney
Biomolecules 2015 ; 5(3):1697-716
PMID: 26213981 [PubMed - as supplied by publisher]


Understanding Caffeine's Role in Attenuating the Toxicity of ?-Synuclein Aggregates: Implications for Risk of Parkinson's Disease.
Jay Kardani, Ipsita Roy
ACS Chem Neurosci 2015 Jul;
PMID: 26167732 [PubMed - as supplied by publisher]


Parkinson disease: Disease-linked morphometric variants of ?-synuclein.
Alex Chase
Nat Rev Neurol 2015 Jul;
PMID: 26149979 [PubMed - as supplied by publisher]


Purinergic signaling in Parkinson's disease. Relevance for treatment.
Gemma Navarro, Dasiel O Borroto-Escuela, Kjell Fuxe, Rafael Franco
Neuropharmacology 2015 Jul;
PMID: 26211977 [PubMed - as supplied by publisher]


Selective loss of dopaminergic neurons in the substantia nigra pars compacta after systemic administration of MPTP facilitates extinction learning.
Ken-Ichi Kinoshita, Yayoi Tada, Yoshikage Muroi, Toshihiro Unno, Toshiaki Ishii
Life Sci 2015 Jul;
PMID: 26209139 [PubMed - as supplied by publisher]


Neuroprotective effects of 3-O-demethylswertipunicoside against MPTP-induced Parkinson's disease in vivo and its antioxidant properties in vitro.
Jun-Jun Zhou, Shen-Yu Zhai, Hui-Nan Zhang, Yue-Hua Wang, Xiao-Ping Pu
Brain Res 2015 Jul;
PMID: 26210618 [PubMed - as supplied by publisher]


?6-Containing Nicotinic Acetylcholine Receptors in Midbrain Dopamine Neurons are Poised to Govern Dopamine-Mediated Behaviors and Synaptic Plasticity.
Jennifer N Berry, Staci E Engle, J Michael McIntosh, Ryan M Drenan
Neuroscience 2015 Jul;
PMID: 26210579 [PubMed - as supplied by publisher]


Alpha-synuclein immunoreactivity patterns in the enteric nervous system.
Iban Aldecoa, Judith Navarro-Otano, Nadia Stefanova, Fabienne S Sprenger, Klaus Seppi, Werner Poewe, Miriam Cuatrecasas, Francesc Valldeoriola, Ellen Gelpi, Eduard Tolosa
Neurosci Lett 2015 Jul; 602:145-149
PMID: 26163460 [PubMed - as supplied by publisher]


Parkinson's disease without nigral degeneration: a pathological correlate of scans without evidence of dopaminergic deficit (SWEDD)?
Helen Ling, Seamus Kearney, Helen Lai Kuen Yip, Laura Silveira-Moriyama, Tamas Revesz, Janice L Holton, Catherine Strand, Karen Davey, Kin Ying Mok, James M Polke, Andrew J Lees
J Neurol Neurosurg Psychiatry 2015 Jul;
PMID: 26209716 [PubMed - as supplied by publisher]


We need to move more: Neurobiological hypotheses of physical exercise as a treatment for Parkinson's disease.
Renato S Monteiro-Junior, Thais Cevada, Bruno R R Oliveira, Eduardo Lattari, Eduardo M M Portugal, Alessandro Carvalho, Andrea C Deslandes
Med Hypotheses 2015 Jul;
PMID: 26209418 [PubMed - as supplied by publisher]


Crocin protects PC12 cells against MPP(+)-induced injury through inhibition of mitochondrial dysfunction and ER stress.
Guo-Feng Zhang, Yi Zhang, Gang Zhao
Neurochem Int 2015 Jul;
PMID: 26209153 [PubMed - as supplied by publisher]


Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson's Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population.
YongPing Chen, Qian-Qian Wei, RuWei Ou, Bei Cao, XuePing Chen, Bi Zhao, XiaoYan Guo, Yuan Yang, Ke Chen, Ying Wu, Wei Song, Hui-Fang Shang
PLoS One 2015 ; 10(7):e0133776
PMID: 26208350 [PubMed - as supplied by publisher]


Alterations in the motor cortical and striatal glutamatergic system and d-serine levels in the bilateral 6-hydroxydopamine rat model for Parkinson's disease.
Anissa El Arfani, Giulia Albertini, Eduard Bentea, Thomas Demuyser, Ann Van Eeckhaut, Ilse Smolders, Ann Massie
Neurochem Int 2015 Jul;
PMID: 26172319 [PubMed - as supplied by publisher]


Disease-modifying strategies for Parkinson's disease.
Lorraine V Kalia, Suneil K Kalia, Anthony E Lang
Mov Disord 2015 Jul;
PMID: 26208210 [PubMed - as supplied by publisher]


Eltoprazine Prevents Dyskinesias by Reducing Striatal Glutamate and Direct Pathway Neuron Activity.
Giovanna Paolone, Alberto Brugnoli, Ludovico Arcuri, Daniela Mercatelli, Michele Morari
Mov Disord 2015 Jul;
PMID: 26207892 [PubMed - as supplied by publisher]


Genetic perspective on the role of the Autophagy-Lysosome Pathway in Parkinson disease.
Ziv Gan-Or, Patrick A Dion, Guy A Rouleau
Autophagy 2015 Jul; :0
PMID: 26207393 [PubMed - as supplied by publisher]


Mathematical models of ?-synuclein transport in axons.
I A Kuznetsov, A V Kuznetsov
Comput Methods Biomech Biomed Engin 2015 Jul; :1-12
PMID: 26207359 [PubMed - as supplied by publisher]


Influence of propofol on oxidative-antioxidative system parameters in peripheral organs of rats with Parkinson disease.
Ewa Romuk, Wioletta Szczurek, Przemys?aw Nowak, Iga Kwiecie?, Dominika Stolecka, Ewa Birkner
Postepy Hig Med Dosw (Online) 2015 ; 69(0):661-7
PMID: 26206983 [PubMed - as supplied by publisher]


High serum phosphate concentration as the result of smoking might underlie the lower risk of Parkinson's disease.
L Håglin
Med Hypotheses 2015 Jun;
PMID: 26206759 [PubMed - as supplied by publisher]


Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by ?-synuclein overexpression.
Mathieu Bourdenx, Sandra Dovero, Michel Engeln, Simone Bido, Matthieu F Bastide, Nathalie Dutheil, Isabel Vollenweider, Laetitia Baud, Camille Piron, Virginie Grouthier, Thomas Boraud, Grégory Porras, Qin Li, Veerle Baekelandt, Dieter Scheller, Anne Michel, Pierre-Olivier Fernagut, François Georges, Grégoire Courtine, Erwan Bezard, Benjamin Dehay
Acta Neuropathol Commun 2015 ; 3(1):46
PMID: 26205255 [PubMed - as supplied by publisher]


Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons.
J Hong, S Sha, L Zhou, C Wang, J Yin, L Chen
Cell Death Dis 2015 ; 6:e1832
PMID: 26203861 [PubMed - as supplied by publisher]


L-F001, a multifunctional ROCK inhibitor prevents paraquat-induced cell death through attenuating ER stress and mitochondrial dysfunction in PC12 cells.
Wei Shen, Lan Wang, Rongbiao Pi, Zhifeng Li, Rikang Wang
Biochem Biophys Res Commun 2015 Jul;
PMID: 26187664 [PubMed - as supplied by publisher]


Heme Stabilization of ?-Synuclein Oligomers during Amyloid Fibril Formation.
Eric Y Hayden, Prerna Kaur, Thomas L Williams, Hiroshi Matsui, Syun-Ru Yeh, Denis L Rousseau
Biochemistry 2015 Jul;
PMID: 26161848 [PubMed - as supplied by publisher]


SNCA rs3822086 C>T Polymorphism Increases the Susceptibility to Parkinson's Disease in a Chinese Han Population.
Chong-Dong Jian, Jian-Min Huang, Lan-Qing Meng, Xue-Bin Li, Rui-Ya Huang, Sheng-Liang Shi, Yuan Wu, Chao Qin, Jin Chen, Yan-Mei Zhang, Shuang Wang, Yin-Ling Feng, Sheng-Nian Zhou
Genet Test Mol Biomarkers 2015 Jul;
PMID: 26203864 [PubMed - as supplied by publisher]


Pycnogenol Protects Against Rotenone-Induced Neurotoxicity in PC12 Cells Through Regulating NF-?B-iNOS Signaling Pathway.
Bo Gao, Chongwang Chang, Jie Zhou, Tianzhi Zhao, Chao Wang, Chen Li, Guodong Gao
DNA Cell Biol 2015 Jul;
PMID: 26203556 [PubMed - as supplied by publisher]


Mutations in presenilin 2 and its implications in Alzheimer's disease and other dementia-associated disorders.
Yan Cai, Seong Soo A An, SangYun Kim
Clin Interv Aging 2015 ; 10:1163-72
PMID: 26203236 [PubMed - as supplied by publisher]


VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for ?-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease.
Fu-Lei Tang, Joanna R Erion, Yun Tian, Wei Liu, Dong-Min Yin, Jian Ye, Baisha Tang, Lin Mei, Wen-Cheng Xiong
J Neurosci 2015 Jul; 35(29):10613-28
PMID: 26203154 [PubMed - as supplied by publisher]


The unfolded protein response is activated in Lewy body dementias.
Jean-Ha Baek, David Whitfield, David Howlett, Paul Francis, Erika Bereczki, Clive Ballard, Tibor Hortobágyi, Johannes Attems, Dag Aarsland
Neuropathol Appl Neurobiol 2015 Jul;
PMID: 26202523 [PubMed - as supplied by publisher]


Serotonergic dysfunction in the A53T alpha-synuclein mouse model of Parkinson's disease.
Janina Deusser, Stefanie Schmidt, Benjamin Ettle, Sonja Plötz, Sabine Huber, Christian P Müller, Eliezer Masliah, Jürgen Winkler, Zacharias Kohl
J Neurochem 2015 Jul;
PMID: 26201615 [PubMed - as supplied by publisher]


Computational Analysis And Functional Prediction Of Ubiquitin Hypothetical Protein: A Possible Target In Parkinson Disease.
Laline Barragan-Osorio, Gustavo Giraldo, Carlos J Almeciga-Diaz, Gjumrakch Aliev, George E Barreto, Janneth Gonzalez
Cent Nerv Syst Agents Med Chem 2015 Jul;
PMID: 26201532 [PubMed - as supplied by publisher]


Assessment of Protective Role of Multifunctional Dopamine Agonist D-512 Against Oxidative Stress Produced by Depletion of Glutathione in PC12 Cells: Implication in Neuroprotective Therapy for Parkinson's Disease.
Chandrashekhar Voshavar, Mrudang Shah, Liping Xu, Aloke K Dutta
Neurotox Res 2015 Jul;
PMID: 26201265 [PubMed - as supplied by publisher]


Oxidative Stress in Neurodegenerative Diseases.
Ewa Niedzielska, Irena Smaga, Maciej Gawlik, Andrzej Moniczewski, Piotr Stankowicz, Joanna Pera, Ma?gorzata Filip
Mol Neurobiol 2015 Jul;
PMID: 26198567 [PubMed - as supplied by publisher]


Clinical and Neuropsychological Differences between Mild Parkinson's Disease Dementia and Dementia with Lewy Bodies.
Mariya Petrova, Shima Mehrabian-Spasova, Dag Aarsland, Margarita Raycheva, Latchezar Traykov
Dement Geriatr Cogn Dis Extra 2015 May-Aug; 5(2):212-20
PMID: 26195977 [PubMed - as supplied by publisher]


Is Cell Death Primary or Secondary in the Pathophysiology of Idiopathic Parkinson's Disease?
Walter J Schulz-Schaeffer
Biomolecules 2015 ; 5(3):1467-79
PMID: 26193328 [PubMed - as supplied by publisher]


Comparison between ?-synuclein wild-type and A53T mutation in a progressive Parkinson's disease model.
Jianqing Lu, Feiyi Sun, Hong Ma, Hong Qing, Yulin Deng
Biochem Biophys Res Commun 2015 Jul;
PMID: 26192120 [PubMed - as supplied by publisher]


Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies.
Anna Villar-Piqué, Tomás Lopes da Fonseca, Tiago Fleming Outeiro
J Neurochem 2015 Jul;
PMID: 26190401 [PubMed - as supplied by publisher]


Loss of glutamic acid decarboxylase (Gad67) in striatal neurons expressing the Drdr1a dopamine receptor prevents l-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned mice.
K Zhang, C Chammas, J-J Soghomonian
Neuroscience 2015 Jul;
PMID: 26188284 [PubMed - as supplied by publisher]


PPAR?/? Agonist Provides Neuroprotection by Suppression of IRE1?-Caspase-12-Mediated Endoplasmic Reticulum Stress Pathway in the Rotenone Rat Model of Parkinson's Disease.
Qiang Tong, Liang Wu, Qing Gao, Zhou Ou, Dongya Zhu, Yingdong Zhang
Mol Neurobiol 2015 Jul;
PMID: 26160761 [PubMed - as supplied by publisher]


The Neuroprotective Effect of Erythropoietin on Rotenone-Induced Neurotoxicity in SH-SY5Y Cells Through the Induction of Autophagy.
Wooyoung Jang, Hee Ju Kim, Huan Li, Kwang Deog Jo, Moon Kyu Lee, Hyun Ok Yang
Mol Neurobiol 2015 Jul;
PMID: 26156288 [PubMed - as supplied by publisher]


The Endocrine Dyscrasia that Accompanies Menopause and Andropause Induces Aberrant Cell Cycle Signaling that Triggers Re-entry of Post-mitotic Neurons into the Cell Cycle, Neurodysfunction, Neurodegeneration and Cognitive Disease.
Craig S Atwood, Richard L Bowen
Horm Behav 2015 Jul;
PMID: 26188949 [PubMed - as supplied by publisher]


NRSF is an essential mediator for the neuroprotection of trichostatin A in the MPTP mouse model of Parkinson's disease.
Haiyun Suo, Pan Wang, Jiabin Tong, Lei Cai, Jie Liu, Dongping Huang, Li Huang, Zishan Wang, Yufang Huang, Jing Xu, Yuanyuan Ma, Mei Yu, Jian Fei, Fang Huang
Neuropharmacology 2015 Jul;
PMID: 26188143 [PubMed - as supplied by publisher]


Neuroprotective effects of (Val8)GLP-1-Glu-PAL in the MPTP Parkinson's disease mouse model.
YanFang Zhang, YiMei Chen, Lin Li, Christian Hölscher
Behav Brain Res 2015 Jul;
PMID: 26187689 [PubMed - as supplied by publisher]


Acerogenin A from Acer nikoense Maxim Prevents Oxidative Stress-Induced Neuronal Cell Death through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse Hippocampal HT22 Cell Line.
Dong-Sung Lee, Byung-Yoon Cha, Je-Tae Woo, Youn-Chul Kim, Jun-Hyeog Jang
Molecules 2015 ; 20(7):12545-57
PMID: 26184139 [PubMed - as supplied by publisher]


Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress.
Alicia M Pickrell, Chiu-Hui Huang, Scott R Kennedy, Alban Ordureau, Dionisia P Sideris, Jake G Hoekstra, J Wade Harper, Richard J Youle
Neuron 2015 Jul; 87(2):371-81
PMID: 26182419 [PubMed - as supplied by publisher]


Aggregated ?-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons.
A K Reeve, M Hr Ludtmann, P R Angelova, E M Simcox, M H Horrocks, D Klenerman, S Gandhi, D M Turnbull, A Y Abramov
Cell Death Dis 2015 ; 6:e1820
PMID: 26181201 [PubMed - as supplied by publisher]


Neurophysiological biomarkers for Lewy body dementias.
Ruth A Cromarty, Greg J Elder, Sara Graziadio, Mark Baker, Laura Bonanni, Marco Onofrj, John T O'Brien, John-Paul Taylor
Clin Neurophysiol 2015 Jun;
PMID: 26183755 [PubMed - as supplied by publisher]


Loss of EEG Network Efficiency Is Related to Cognitive Impairment in Dementia With Lewy Bodies.
Edwin van Dellen, Hanneke de Waal, Wiesje M van der Flier, Afina W Lemstra, Arjen J C Slooter, Lieke L Smits, Elisabeth C W van Straaten, Cornelis J Stam, Philip Scheltens
Mov Disord 2015 Jul;
PMID: 26179663 [PubMed - as supplied by publisher]


Colonic bacterial composition in Parkinson's disease.
Ali Keshavarzian, Stefan J Green, Phillip A Engen, Robin M Voigt, Ankur Naqib, Christopher B Forsyth, Ece Mutlu, Kathleen M Shannon
Mov Disord 2015 Jul;
PMID: 26179554 [PubMed - as supplied by publisher]


Chemical biology of compounds obtained from screening using disease models.
Estu Tashiro, Masaya Imoto
Arch Pharm Res 2015 Jul;
PMID: 26177809 [PubMed - as supplied by publisher]


Basic science breaks through: New therapeutic advances in Parkinson's disease.
Patrik Brundin, Graham Atkin, Jennifer T Lamberts
Mov Disord 2015 Jul;
PMID: 26177603 [PubMed - as supplied by publisher]


Protective Effects of Physical Exercise in Alzheimer's Disease and Parkinson's Disease: A Narrative Review.
Thierry Paillard, Yves Rolland, Philipe de Souto Barreto
J Clin Neurol 2015 Jul; 11(3):212-9
PMID: 26174783 [PubMed - as supplied by publisher]


Distinctive Distribution of phospho-alpha-synuclein in dermal nerves in multiple system atrophy.
Kathrin Doppler, Jessica Weis, Katharina Karl, Sönke Ebert, Jens Ebentheuer, Claudia Trenkwalder, Stephan Klebe, Jens Volkmann, Claudia Sommer
Mov Disord 2015 Jul;
PMID: 26175301 [PubMed - as supplied by publisher]


Group comparison of spatiotemporal dynamics of intrinsic networks in Parkinson's disease.
Tara M Madhyastha, Mary K Askren, Jing Zhang, James B Leverenz, Thomas J Montine, Thomas J Grabowski
Brain 2015 Jul;
PMID: 26173859 [PubMed - as supplied by publisher]


L-dopa increases ?-synuclein DNA methylation in Parkinson's disease patients in vivo and in vitro.
Ina Schmitt, Oliver Kaut, Hassan Khazneh, Laura deBoni, Ashar Ahmad, Daniela Berg, Christine Klein, Holger Fröhlich, Ullrich Wüllner
Mov Disord 2015 Jul;
PMID: 26173746 [PubMed - as supplied by publisher]


FoxO Proteins in the Nervous System.
Kenneth Maiese
Anal Cell Pathol (Amst) 2015 ; 2015:569392
PMID: 26171319 [PubMed - as supplied by publisher]


Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery.
Agnes Aruna John, Aruna Priyadharshni Subramanian, Muthu Vignesh Vellayappan, Arunpandian Balaji, Hemanth Mohandas, Saravana Kumar Jaganathan
Int J Nanomedicine 2015 ; 10:4267-77
PMID: 26170663 [PubMed - as supplied by publisher]


Oxidative Stress in Patients with X-Linked Adrenoleukodystrophy.
Marion Deon, Desirèe P Marchetti, Bruna Donida, Moacir Wajner, Carmen Vargas
Cell Mol Neurobiol 2015 Jul;
PMID: 26169524 [PubMed - as supplied by publisher]


Insulin and the Brain: A Sweet Relationship With Intensive Care.
F Bilotta, M P Lauretta, A Tewari, M Haque, N Hara, H Uchino, G Rosa
J Intensive Care Med 2015 Jul;
PMID: 26168800 [PubMed - as supplied by publisher]


Diverse Short-Term Dynamics of Inhibitory Synapses Converging on Striatal Projection Neurons: Differential Changes in a Rodent Model of Parkinson's Disease.
Janet Barroso-Flores, Marco A Herrera-Valdez, Violeta Gisselle Lopez-Huerta, Elvira Galarraga, José Bargas
Neural Plast 2015 ; 2015:573543
PMID: 26167304 [PubMed - as supplied by publisher]


Transgenic supplementation of SIRT1 fails to alleviate acute loss of nigrostriatal dopamine neurons and gliosis in a mouse model of MPTP-induced parkinsonism.
Yasuko Kitao, Natsumi Ageta-Ishihara, Ryosuke Takahashi, Makoto Kinoshita, Osamu Hori
F1000Res 2015 ; 4:130
PMID: 26167274 [PubMed - as supplied by publisher]


Neuroprotective Properties of the Standardized Extract from Camellia sinensis (Green Tea) and Its Main Bioactive Components, Epicatechin and Epigallocatechin Gallate, in the 6-OHDA Model of Parkinson's Disease.
Natália Bitu Pinto, Bruno da Silva Alexandre, Kelly Rose Tavares Neves, Aline Holanda Silva, Luzia Kalyne A M Leal, Glauce S B Viana
Evid Based Complement Alternat Med 2015 ; 2015:161092
PMID: 26167188 [PubMed - as supplied by publisher]


Astrocytes: new targets for the treatment of neurodegenerative diseases.
Charles Finsterwald, Pierre J Magistretti, Sylvain Lengacher
Curr Pharm Des 2015 Jul;
PMID: 26166612 [PubMed - as supplied by publisher]


Biochemical protective effect of 1,25-dihydroxyvitamin D3 through autophagy induction in the MPTP mouse model of Parkinson's disease.
Huan Li, Wooyoung Jang, Hee Ju Kim, Kwang Deog Jo, Moon Kyu Lee, Sun Hong Song, Hyun Ok Yang
Neuroreport 2015 Aug; 26(12):669-74
PMID: 26164453 [PubMed - as supplied by publisher]


MPTP activates ASK1-p38 MAPK signaling pathway through TNF-dependent Trx1 oxidation in Parkinsonism mouse model.
Ajit Ray, Neha Sehgal, Smitha Karunakaran, Govindan Rangarajan, Vijayalakshmi Ravindranath
Free Radic Biol Med 2015 Jul;
PMID: 26164633 [PubMed - as supplied by publisher]


Neuroprotective effects of Kukoamine B against hydrogen peroxide-induced apoptosis and potential mechanisms in SH-SY5Y cells.
Xiao-Long Hu, Yi-Xuan Niu, Qiao Zhang, Xing Tian, Ling-Yue Gao, Li-Ping Guo, Wei-Hong Meng, Qing-Chun Zhao
Environ Toxicol Pharmacol 2015 Jun; 40(1):230-240
PMID: 26164594 [PubMed - as supplied by publisher]


Genetic analysis of the RAB39B gene in Chinese Han patients with Parkinson's disease.
Lamei Yuan, Xiong Deng, Zhi Song, Zhijian Yang, Bin Ni, Yong Chen, Hao Deng
Neurobiol Aging 2015 Jun;
PMID: 26163985 [PubMed - as supplied by publisher]


H2S: A New Approach to Lifespan Enhancement and Healthy Ageing?
Bedoor Qabazard, Stephen R Stürzenbaum
Handb Exp Pharmacol 2015 ; 230:269-87
PMID: 26162840 [PubMed - as supplied by publisher]


(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation.
Fabienne C Fiesel, Maya Ando, Roman Hudec, Anneliese R Hill, Monica Castanedes-Casey, Thomas R Caulfield, Elisabeth L Moussaud-Lamodière, Jeannette N Stankowski, Peter O Bauer, Oswaldo Lorenzo-Betancor, Isidre Ferrer, José M Arbelo, Joanna Siuda, Li Chen, Valina L Dawson, Ted M Dawson, Zbigniew K Wszolek, Owen A Ross, Dennis W Dickson, Wolfdieter Springer
EMBO Rep 2015 Jul;
PMID: 26162776 [PubMed - as supplied by publisher]


Parkin Is Dispensable for Mitochondrial Function, but Its Ubiquitin Ligase Activity Is Critical for Macroautophagy and Neurotransmitters: Therapeutic Potential beyond Parkinson's Disease.
Charbel E-H Moussa
Neurodegener Dis 2015 Jul;
PMID: 26160424 [PubMed - as supplied by publisher]


Low alpha-synuclein levels in the blood are associated with insulin resistance.
Gerardo Rodriguez-Araujo, Hironori Nakagami, Yoichi Takami, Tomohiro Katsuya, Hiroshi Akasaka, Shigeyuki Saitoh, Kazuaki Shimamoto, Ryuichi Morishita, Hiromi Rakugi, Yasufumi Kaneda
Sci Rep 2015 ; 5:12081
PMID: 26159928 [PubMed - as supplied by publisher]


Mutations in LRRK2 potentiate age-related impairment of autophagic flux.
Shamol Saha, Peter E A Ash, Vivek Gowda, Liqun Liu, Orian Shirihai, Benjamin Wolozin
Mol Neurodegener 2015 ; 10(1):26
PMID: 26159606 [PubMed - as supplied by publisher]


Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.
J C Koch, F Bitow, J Haack, Z d'Hedouville, J-N Zhang, L Tönges, U Michel, L M A Oliveira, T M Jovin, J Liman, L Tatenhorst, M Bähr, P Lingor
Cell Death Dis 2015 ; 6:e1811
PMID: 26158517 [PubMed - as supplied by publisher]


Computational Psychiatry: towards a mathematically informed understanding of mental illness.
Rick A Adams, Quentin J M Huys, Jonathan P Roiser
J Neurol Neurosurg Psychiatry 2015 Jul;
PMID: 26157034 [PubMed - as supplied by publisher]


Serological Analysis of Alpha-synuclein and NF-?B in Parkinson's Disease Patients.
Vineeta Gupta, Ravindra Kumar Garg, Sanjay Khattri
J Clin Diagn Res 2015 May; 9(5):BC01-4
PMID: 26155470 [PubMed - as supplied by publisher]


Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features.
Gunnar F Kwakye, Monica M B Paoliello, Somshuvra Mukhopadhyay, Aaron B Bowman, Michael Aschner
Int J Environ Res Public Health 2015 ; 12(7):7519-40
PMID: 26154659 [PubMed - as supplied by publisher]


Metabolomics Approach Reveals Integrated Metabolic Network Associated with Serotonin Deficiency.
Rui Weng, Sensen Shen, Yonglu Tian, Casey Burton, Xinyuan Xu, Yi Liu, Cuilan Chang, Yu Bai, Huwei Liu
Sci Rep 2015 ; 5:11864
PMID: 26154191 [PubMed - as supplied by publisher]


Lesion of medulla's catecholaminergic neurons is associated with cardiovascular dysfunction in rotenone-induced Parkinson's disease rats.
Zhaoqiang Zhang, Xixun Du, Huamin Xu, Junxia Xie, Hong Jiang
Eur J Neurosci 2015 Jul;
PMID: 26153521 [PubMed - as supplied by publisher]


Diffusion Kurtosis Imaging Detects Microstructural Alterations in Brain of ?-Synuclein Overexpressing Transgenic Mouse Model of Parkinson's Disease: A Pilot Study.
Amit Khairnar, Peter Latta, Eva Drazanova, Jana Ruda-Kucerova, Nikoletta Szabó, Anas Arab, Birgit Hutter-Paier, Daniel Havas, Manfred Windisch, Alexandra Sulcova, Zenon Starcuk, Irena Rektorova
Neurotox Res 2015 Jul;
PMID: 26153486 [PubMed - as supplied by publisher]


KTKEGV repeat motifs are key mediators of normal ?-synuclein tetramerization: Their mutation causes excess monomers and neurotoxicity.
Ulf Dettmer, Andrew J Newman, Victoria E von Saucken, Tim Bartels, Dennis Selkoe
Proc Natl Acad Sci U S A 2015 Jul;
PMID: 26153422 [PubMed - as supplied by publisher]


Fundamental mechanisms of amyloid fibril formation by alpha-synuclein in Parkinson's disease: quantitative modelling].
Céline Galvagnion, Alexander K Buell
Med Sci (Paris) 2015 Jun-Jul; 31(6-7):597-600
PMID: 26152159 [PubMed - as supplied by publisher]


Does it matter who organises your health care?
Paresh Dawda, Ian S McRae, Laurann Yen, Md Mofizul Islam, Nasser Bagheri, Tanisha Jowsey, Michelle Banfield, Anne Parkinson
Int J Integr Care 2015 Apr-Jun; 15:e022
PMID: 26150760 [PubMed - as supplied by publisher]


Increased oligomerization and phosphorylation of ?-synuclein are associated with decreased activity of glucocerebrosidase and protein phosphatase 2A in aging monkey brains.
Guangwei Liu, Min Chen, Na Mi, Weiwei Yang, Xin Li, Peng Wang, Na Yin, Yaohua Li, Feng Yue, Piu Chan, Shun Yu
Neurobiol Aging 2015 Jun;
PMID: 26149921 [PubMed - as supplied by publisher]


The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role Against ?-Synuclein Oligomers.
Cristiane Latge, Katia M S Cabral, Guilherme A P de Oliveira, Diana P Raymundo, Julia A Freitas, Laizes Johanson, Luciana F Romão, Fernando L Palhano, Torsten Herrmann, Marcius S Almeida, Debora Foguel
J Biol Chem 2015 Jul;
PMID: 26149686 [PubMed - as supplied by publisher]