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Featured Research

What can we learn by studying exercise and Parkinson's? PDF-funded researcher Kristen Pickett, Ph.D., is using magnetic resonance imaging to help find answers to improve life for people with PD.

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Causes and Pathology

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.

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Understanding Parkinson’s

Motor Symptoms


    Balance and Falls
    Gait or Freezing

    Nonmotor Symptoms and Complications



Sleep and Fatigue/ REM Behavior Sleep Disorder

    Gastrointestinal and Urinary Function

    Cognition and Hallucination

Impulse Control Disorder

Vision/Visual hallucination



Orthostatic Hypotension


Imaging Studies

Clinical Studies



Treating Parkinson’s

Current and potential medications/Therapies

    Surgical Treatments
Gene Therapy

Deep Brain Stimulation

Physical, Occupational and Speech Therapy



Art and Music

Complementary and Alternative Therapies

Living with a Parkinson’s Diagnosis



Care giving

Hospice/End of Life/Palliative Care

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Transcriptomics of Maternal and Fetal Membranes Can Discriminate between Gestational-Age Matched Preterm Neonates with and without Cognitive Impairment Diagnosed at 18-24 Months.
Athina Pappas, Tinnakorn Chaiworapongsa, Roberto Romero, Steven J Korzeniewski, Josef C Cortez, Gaurav Bhatti, Nardhy Gomez-Lopez, Sonia S Hassan, Seetha Shankaran, Adi L Tarca
PLoS One 2015 ; 10(3):e0118573
PMID: 25822971 [PubMed - as supplied by publisher]

DJ-1 Knockout Augments Disease Severity and Shortens Survival in a Mouse Model of ALS.
Nirit Lev, Yael Barhum, Itay Lotan, Israel Steiner, Daniel Offen
PLoS One 2015 ; 10(3):e0117190
PMID: 25822630 [PubMed - as supplied by publisher]

Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling.
Shanshan Gao, Chunli Duan, Ge Gao, Xiaoming Wang, Hui Yang
Int J Biochem Cell Biol 2015 Mar;
PMID: 25813876 [PubMed - as supplied by publisher]

An association between organophosphate pesticides exposure and Parkinsonism amongst people in an agricultural area in Ubon Ratchathani Province, Thailand.
Saowanee Norkaew, Somrat Lertmaharit, Wachiraporn Wilaiwan, Wattasit Siriwong, Héctor Maldonado Pérez, Mark G Robson
Rocz Panstw Zakl Hig 2015; 66(1):21-26
PMID: 25813069 [PubMed - as supplied by publisher]

Dual ?-agonist/?-antagonist opioid receptor modulation reduces levodopa-induced dyskinesia and corrects dysregulated striatal changes in the nonhuman primate model of Parkinson disease.
Lisa F Potts, Eun S Park, Jong-Min Woo, Bhagya L Dyavar Shetty, Arun Singh, Steven P Braithwaite, Michael Voronkov, Stella M Papa, M Maral Mouradian
Ann Neurol 2015 Mar;
PMID: 25820831 [PubMed - as supplied by publisher]

Gaucher-Associated Parkinsonism.
Yaqiong Li, Ping Li, Huimin Liang, Zhiquan Zhao, Makoto Hashimoto, Jianshe Wei
Cell Mol Neurobiol 2015 Mar;
PMID: 25820783 [PubMed - as supplied by publisher]

Syndromic parkinsonism and dementia associated with OPA1 missense mutations.
Valerio Carelli, Olimpia Musumeci, Leonardo Caporali, Claudia Zanna, Chiara La Morgia, Valentina Del Dotto, Anna Maria Porcelli, Michela Rugolo, Maria Lucia Valentino, Luisa Iommarini, Alessandra Maresca, Piero Barboni, Michele Carbonelli, Costantino Trombetta, Enza Maria Valente, Simone Patergnani, Carlotta Giorgi, Paolo Pinton, Giovanni Rizzo, Caterina Tonon, Raffaele Lodi, Patrizia Avoni, Rocco Liguori, Agostino Baruzzi, Antonio Toscano, Massimo Zeviani
Ann Neurol 2015 Mar;
PMID: 25820230 [PubMed - as supplied by publisher]

The diagnostic value of minor salivary gland biopsy in clinically diagnosed patients with Parkinson's disease: comparison with DAT PET scans.
Liyan Gao, Huimin Chen, Xin Li, Fangfei Li, Qiaohong Ou-Yang, Tao Feng
Neurol Sci 2015 Mar;
PMID: 25820147 [PubMed - as supplied by publisher]

Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions.
Jason M Hinzman, Vince A DiNapoli, Eric J Mahoney, Greg A Gerhardt, Jed A Hartings
Exp Neurol 2015 Mar;
PMID: 25819105 [PubMed - as supplied by publisher]

Ser129 phosphorylation of endogenous ?-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.
Kerstin Buck, Natalie Landeck, Ayse Ulusoy, Nour K Majbour, Omar M A El-Agnaf, Deniz Kirik
Neurobiol Dis 2015 Mar;
PMID: 25818009 [PubMed - as supplied by publisher]

Parkinson disease: ?-synuclein mutational screening and new clinical insight into the p.E46K mutation.
Márcia M G Pimentel, Fabíola C Rodrigues, Marco Antônio A Leite, Mário Campos Júnior, Ana Lucia Rosso, Denise H Nicaretta, Joăo S Pereira, Delson José Silva, Marcus V Della Coletta, Luiz Felipe R Vasconcellos, Gabriella M Abreu, Jussara M Dos Santos, Cíntia B Santos-Rebouças
Parkinsonism Relat Disord 2015 Mar;
PMID: 25817515 [PubMed - as supplied by publisher]

A Peruvian family with a novel PARK2 mutation: Clinical and pathological characteristics.
Mario R Cornejo-Olivas, Luis Torres, Ignacio F Mata, Pilar Mazzetti, Diana Rivas, Carlos Cosentino, Miguel Inca-Martinez, Juan M Cuba, Cyrus P Zabetian, James B Leverenz
Parkinsonism Relat Disord 2015 Jan;
PMID: 25817512 [PubMed - as supplied by publisher]

Glucocerebrosidase and Parkinson disease: Recent advances.
A H V Schapira
Mol Cell Neurosci 2015 Mar;
PMID: 25802027 [PubMed - as supplied by publisher]

The protein l-isoaspartyl (d-aspartyl) methyltransferase protects against dopamine-induced apoptosis in neuroblastoma SH-SY5Y cells.
D Ouazia, L-C Levros, É Rassart, R R Desrosiers
Neuroscience 2015 Mar;
PMID: 25800307 [PubMed - as supplied by publisher]

Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases.
Tomohiro Nakamura, Olga A Prikhodko, Elaine Pirie, Saumya Nagar, Mohd Waseem Akhtar, Chang-Ki Oh, Scott R McKercher, Rajesh Ambasudhan, Shu-Ichi Okamoto, Stuart A Lipton
Neurobiol Dis 2015 Mar;
PMID: 25796565 [PubMed - as supplied by publisher]

The kynurenine pathway and neurodegenerative disease.
Daniel C Maddison, Flaviano Giorgini
Semin Cell Dev Biol 2015 Mar;
PMID: 25773161 [PubMed - as supplied by publisher]

Plasmalogen precursor analog treatment reduces levodopa-induced dyskinesias in parkinsonian monkeys.
Laurent Grégoire, Tara Smith, Vijitha Senanayake, Asuka Mochizuki, Edith Miville-Godbout, Dayan Goodenowe, Thérčse Di Paolo
Behav Brain Res 2015 Mar; 286:328-337
PMID: 25771209 [PubMed - as supplied by publisher]

Interrogating the aged striatum: Robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration.
Timothy J Collier, Jennifer O'Malley, David J Rademacher, Jennifer A Stancati, Kellie A Sisson, Caryl E Sortwell, Katrina L Paumier, Kibrom G Gebremedhin, Kathy Steece-Collier
Neurobiol Dis 2015 Mar; 77:191-203
PMID: 25771169 [PubMed - as supplied by publisher]

Discovery of novel anti-parkinsonian effect of schisantherin A in in vitro and in vivo.
Fei Sa, Lun Qing Zhang, Cheong Meng Chong, Bao Jian Guo, Sai Li, Zai Jun Zhang, Ying Zheng, Pui Man Hoi, Simon Ming Yuen Lee
Neurosci Lett 2015 Mar; 593:7-12
PMID: 25770828 [PubMed - as supplied by publisher]

Environmental factors as modulators of neurodegeneration: Insights from gene-environment interactions in Huntington's disease.
Christina Mo, Anthony J Hannan, Thibault Renoir
Neurosci Biobehav Rev 2015 Mar; 52:178-192
PMID: 25770041 [PubMed - as supplied by publisher]

MPTP-induced parkinsonism in mice alters striatal and nigral xCT expression but is unaffected by the genetic loss of xCT.
Eduard Bentea, Michelle D Sconce, Madeline J Churchill, Joeri Van Liefferinge, Hideyo Sato, Charles K Meshul, Ann Massie
Neurosci Lett 2015 Mar; 593:1-6
PMID: 25766755 [PubMed - as supplied by publisher]

Neuroprotective effects of vildagliptin in rat rotenone Parkinson's disease model: role of RAGE-NF?B and Nrf2-antioxidant signaling pathways.
Rania M Abdelsalam, Marwa M Safar
J Neurochem 2015 Mar;
PMID: 25752913 [PubMed - as supplied by publisher]

Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and l-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator and an orthosteric agonist.
Hanna Iderberg, Natallia Maslava, Analisa D Thompson, Michael Bubser, Colleen M Niswender, Corey R Hopkins, Craig W Lindsley, P Jeffrey Conn, Carrie K Jones, M Angela Cenci
Neuropharmacology 2015 Mar; 95:121-129
PMID: 25749357 [PubMed - as supplied by publisher]

Changes in the expression of genes encoding for mGlu4 and mGlu5 receptors and other regulators of the indirect pathway in acute mouse models of drug-induced parkinsonism.
Milena Cannella, Marta Motolese, Domenico Bucci, Gemma Molinaro, Roberto Gradini, Valeria Bruno, Ferdinando Nicoletti, Giuseppe Battaglia
Neuropharmacology 2015 Mar; 95:50-58
PMID: 25747602 [PubMed - as supplied by publisher]

A newly discovered neurotoxin ADTIQ associated with hyperglycemia and Parkinson's disease.
Bingjie Xie, Fankai Lin, Kaleem Ullah, Lei Peng, Wei Ding, Rongji Dai, Hong Qing, Yulin Deng
Biochem Biophys Res Commun 2015 Apr; 459(3):361-6
PMID: 25744031 [PubMed - as supplied by publisher]

Seeking a Mechanism for the Toxicity of Oligomeric ?-Synuclein.
Hazel L Roberts, David R Brown
Biomolecules 2015; 5(2):282-305
PMID: 25816357 [PubMed - as supplied by publisher]

Association of Parkinson's Disease and Its Subtypes with Agricultural Pesticide Exposures in Men: A Case-Control Study in France.
Frédéric Moisan, Johan Spinosi, Laurčne Delabre, Véronique Gourlet, Jean-Louis Mazurie, Isabelle Bénatru, Marcel Goldberg, Marc G Weisskopf, Ellen Imbernon, Christophe Tzourio, Alexis Elbaz
Environ Health Perspect 2015 Mar;
PMID: 25815770 [PubMed - as supplied by publisher]

Mitochondrial dysfunction in Parkinson disease: evidence in mutant PARK2 fibroblasts.
Maria C Zanellati, Valentina Monti, Chiara Barzaghi, Chiara Reale, Nardo Nardocci, Alberto Albanese, Enza M Valente, Daniele Ghezzi, Barbara Garavaglia
Front Genet 2015; 6:78
PMID: 25815004 [PubMed - as supplied by publisher]

Midbrain catecholaminergic neurons co-express ?-synuclein and tau in progressive supranuclear palsy.
María Elena Erro Aguirre, María Victoria Zelaya, Javier Sánchez Ruiz de Gordoa, María Teresa Tuńón, José Luis Lanciego
Front Neuroanat 2015; 9:25
PMID: 25814937 [PubMed - as supplied by publisher]

Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins.
Ralf J Braun
Front Mol Neurosci 2015; 8:8
PMID: 25814926 [PubMed - as supplied by publisher]

MicroRNA-7 promotes glycolysis to protect against 1-methyl-4-phenylpyridinium-induced cell death.
Amrita Datta Chaudhuri, Savan Kabaria, Doo Chul Choi, M Maral Mouradian, Eunsung Junn
J Biol Chem 2015 Mar;
PMID: 25814668 [PubMed - as supplied by publisher]

Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and ?-synuclein aggregation.
Eun-Jin Bae, Na Young Yang, Cheolsoon Lee, He-Jin Lee, Seokjoong Kim, Sergio Pablo Sardi, Seung-Jae Lee
Exp Mol Med 2015; 47:e153
PMID: 25813221 [PubMed - as supplied by publisher]

Glia and alpha-synuclein in neurodegeneration: A complex interaction.
Dominik Brück, Gregor K Wenning, Nadia Stefanova, Lisa Fellner
Neurobiol Dis 2015 Mar;
PMID: 25766679 [PubMed - as supplied by publisher]

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease.
Brent J Ryan, Selim Hoek, Edward A Fon, Richard Wade-Martins
Trends Biochem Sci 2015 Apr; 40(4):200-210
PMID: 25757399 [PubMed - as supplied by publisher]

Attenuation of neuromotor deficits by natural antioxidants of Decalepis hamiltonii in transgenic Drosophila model of Parkinson's disease.
S R Jahromi, M Haddadi, T Shivanandappa, S R Ramesh
Neuroscience 2015 Mar; 293:136-150
PMID: 25754960 [PubMed - as supplied by publisher]

Mitochondrial transfer from Wharton's jelly-derived mesenchymal stem cells to mitochondria-defective cells recaptures impaired mitochondrial function.
Hung-Yu Lin, Chia-Wei Liou, Shang-Der Chen, Te-Yao Hsu, Jiin-Haur Chuang, Pei-Wen Wang, Sheng-Teng Huang, Mao-Meng Tiao, Jin-Bor Chen, Tsu-Kung Lin, Yao-Chung Chuang
Mitochondrion 2015 Mar; 22:31-44
PMID: 25746175 [PubMed - as supplied by publisher]

Ellagic acid improves hyperalgesia and cognitive deficiency in 6-hydroxidopamine induced rat model of Parkinson's disease.
Mojtaba Dolatshahi, Yaghoob Farbood, Alireza Sarkaki, Seyed Mohammad Taqhi Mansouri, Ali Khodadadi
Iran J Basic Med Sci 2015 Jan; 18(1):38-46
PMID: 25810874 [PubMed - as supplied by publisher]

What we can learn from animal models about cerebral multi-morbidity.
Siân Baker, Jürgen Götz
Alzheimers Res Ther 2015 ; 7(1):11
PMID: 25810783 [PubMed - as supplied by publisher]

Apathy in Neurodegenerative Diseases: Recommendations on the Design of Clinical Trials.
Jeffrey Cummings, Joseph H Friedman, George Garibaldi, Martin Jones, Wayne Macfadden, Laura Marsh, Philippe H Robert
J Geriatr Psychiatry Neurol 2015 Mar;
PMID: 25809634 [PubMed - as supplied by publisher]

Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease.
Scarlet Gallegos, Carla Pacheco, Christian Peters, Carlos M Opazo, Luis G Aguayo
Front Neurosci 2015 ; 9:59
PMID: 25805964 [PubMed - as supplied by publisher]

Lack of exacerbation of neurodegeneration in a double transgenic mouse model of mutant LRRK2 and tau.
Fadi Mikhail, Noel Calingasan, Luca Parolari, Aarthi Subramanian, Lichuan Yang, M Flint Beal
Hum Mol Genet 2015 Mar;
PMID: 25804954 [PubMed - as supplied by publisher]

Studying nitrosative stress in Parkinson's disease.
Kenny K K Chung
Methods Mol Biol 2015 ; 1292:195-201
PMID: 25804757 [PubMed - as supplied by publisher]

Effect of homocysteine on survival of human glial cells.
H ?kovierová, S Mahmood, E Blahovcová, J Hatok, J Lehotský, R Murín
Physiol Res 2015 Mar;
PMID: 25804098 [PubMed - as supplied by publisher]

Web-based telemonitoring and delivery of caregiver support for patients with Parkinson disease after deep brain stimulation: protocol.
Sara Marceglia, Elena Rossi, Manuela Rosa, Filippo Cogiamanian, Lorenzo Rossi, Laura Bertolasi, Alberto Vogrig, Francesco Pinciroli, Sergio Barbieri, Alberto Priori
JMIR Res Protoc 2015 ; 4(1):e30
PMID: 25803512 [PubMed - as supplied by publisher]

Cytotoxic helix-rich oligomer formation by melittin and pancreatic polypeptide.
Pradeep K Singh, Dhiman Ghosh, Debanjan Tewari, Ganesh M Mohite, Edmund Carvalho, Narendra Nath Jha, Reeba S Jacob, Shruti Sahay, Rinti Banerjee, Amal K Bera, Samir K Maji
PLoS One 2015 ; 10(3):e0120346
PMID: 25803428 [PubMed - as supplied by publisher]

The Toll-like Receptor Radical Cycle pathway: a new drug target in immune-related chronic fatigue.
K Lucas, G Morris, G Anderson, M Maes
CNS Neurol Disord Drug Targets 2015 Mar;
PMID: 25801843 [PubMed - as supplied by publisher]

Lewy bodies: A spectator or salient killer?
J Sian-Hülsmann, C Monoranu, S Strobel, P Riederer
CNS Neurol Disord Drug Targets 2015 Mar;
PMID: 25801839 [PubMed - as supplied by publisher]

Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria.
Yvette C Wong, Erika L F Holzbaur
Autophagy 2015 Mar; :0
PMID: 25801386 [PubMed - as supplied by publisher]

Activation of Necroptosis in Multiple Sclerosis.
Dimitry Ofengeim, Yasushi Ito, Ayaz Najafov, Yaoyang Zhang, Bing Shan, Judy Park DeWitt, Juanying Ye, Xumin Zhang, Ansi Chang, Helin Vakifahmetoglu-Norberg, Jiefei Geng, Benedicte Py, Wen Zhou, Palak Amin, Jonilson Berlink Lima, Chunting Qi, Qiang Yu, Bruce Trapp, Junying Yuan
Cell Rep 2015 Mar;
PMID: 25801023 [PubMed - as supplied by publisher]

Olfactory Dysfunction and Neurotransmitter Disturbance in Olfactory Bulb of Transgenic Mice Expressing Human A53T Mutant ?-Synuclein.
Sufang Zhang, Qian Xiao, Weidong Le
PLoS One 2015 ; 10(3):e0119928
PMID: 25799501 [PubMed - as supplied by publisher]

3-Anhydro-6-hydroxy-ophiobolin A, a fungal sesterterpene from Bipolaris oryzae induced autophagy and promoted the degradation of ?-synuclein in PC12 cells.
Danfeng Xue, Quanxin Wang, Ziheng Chen, Lei Cai, Li Bao, Qiuyue Qi, Lei Liu, Xiaohui Wang, Haijing Jin, Jun Wang, Hao Wu, Hongwei Liu, Quan Chen
Bioorg Med Chem Lett 2015 Apr; 25(7):1464-70
PMID: 25748161 [PubMed - as supplied by publisher]

Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's disease.
Marta Esteves, Ana C Cristóvăo, Tatiana Saraiva, Sandra M Rocha, Graça Baltazar, Lino Ferreira, Liliana Bernardino
Front Aging Neurosci 2015 ; 7:20
PMID: 25798108 [PubMed - as supplied by publisher]

Compensatory mechanisms in genetic models of neurodegeneration: are the mice better than humans?
Grzegorz Kreiner
Front Cell Neurosci 2015 ; 9:56
PMID: 25798086 [PubMed - as supplied by publisher]

Effects of (-)-sesamin on 6-hydroxydopamine-induced neurotoxicity in PC12 cells and dopaminergic neuronal cells of Parkinson's disease rat models.
Hyun Jin Park, Ting Ting Zhao, Kyung Sook Lee, Seung Ho Lee, Keon Sung Shin, Keun Hong Park, Hyun Sook Choi, Myung Koo Lee
Neurochem Int 2015 Mar;
PMID: 25747493 [PubMed - as supplied by publisher]

Identification of novel biomarkers for Parkinson's disease by metabolomic technologies.
Taku Hatano, Shinji Saiki, Ayami Okuzumi, Robert P Mohney, Nobutaka Hattori
J Neurol Neurosurg Psychiatry 2015 Mar;
PMID: 25795009 [PubMed - as supplied by publisher]

Ozlem Ozsoy, Fatos Belgin Yildirim, Eren Ogut, Yasemin Kaya, Gamze Tanriover, Hande Parlak, Aysel Agar, Mutay Aslan
Free Radic Res 2015 Mar; :1-33
PMID: 25791066 [PubMed - as supplied by publisher]

In Process Citation].
Alexander Kurz, Timo Grimmer
Ther Umsch 2015 Apr; 72(4):279-85
PMID: 25791052 [PubMed - as supplied by publisher]

Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated ?-Synuclein.
Kiri Kilpatrick, Yimeng Zeng, Tommy Hancock, Laura Segatori
PLoS One 2015 ; 10(3):e0120819
PMID: 25790376 [PubMed - as supplied by publisher]

Molecular Details of ?-Synuclein Membrane Association Revealed by Neutrons and Photons.
Zhiping Jiang, Sara K Hess, Frank Heinrich, Jennifer C Lee
J Phys Chem B 2015 Mar;
PMID: 25790164 [PubMed - as supplied by publisher]

Iron and Parkinson's disease.
Francesco Di Lorenzo
Neuro Endocrinol Lett 2015 Feb; 36(1)
PMID: 25789591 [PubMed - as supplied by publisher]

Echinacoside Protects against 6-Hydroxydopamine-Induced Mitochondrial Dysfunction and Inflammatory Responses in PC12 Cells via Reducing ROS Production.
Yue-Hua Wang, Zhao-Hong Xuan, Shuo Tian, Guan-Hua Du
Evid Based Complement Alternat Med 2015 ; 2015:189239
PMID: 25788961 [PubMed - as supplied by publisher]

Targeting ?-synuclein oligomers by protein-fragment complementation for drug discovery in synucleinopathies.
Simon Moussaud, Siobhan Malany, Alka Mehta, Stefan Vasile, Layton H Smith, Pamela J McLean
Expert Opin Ther Targets 2015 Mar; :1-15
PMID: 25785645 [PubMed - as supplied by publisher]

Coffee, Genetic Variants, and Parkinson's Disease: Gene-Environment Interactions.
Naomi Yamada-Fowler, Peter Söderkvist
J Caffeine Res 2015 Mar; 5(1):3-10
PMID: 25785234 [PubMed - as supplied by publisher]

Modulation of the glutamatergic transmission by Dopamine: a focus on Parkinson, Huntington and Addiction diseases.
Fabrizio Gardoni, Camilla Bellone
Front Cell Neurosci 2015 ; 9:25
PMID: 25784855 [PubMed - as supplied by publisher]

Structure based aggregation studies reveal the presence of helix-rich intermediate during ?-Synuclein aggregation.
Dhiman Ghosh, Pradeep K Singh, Shruti Sahay, Narendra Nath Jha, Reeba S Jacob, Shamik Sen, Ashutosh Kumar, Roland Riek, Samir K Maji
Sci Rep 2015 ; 5:9228
PMID: 25784353 [PubMed - as supplied by publisher]

Differentiation of human induced pluripotent stem cells to mature functional Purkinje neurons.
Shuyan Wang, Bin Wang, Na Pan, Linlin Fu, Chaodong Wang, Gongru Song, Jing An, Zhongfeng Liu, Wanwan Zhu, Yunqian Guan, Zhi-Qing David Xu, Piu Chan, Zhiguo Chen, Y Alex Zhang
Sci Rep 2015 ; 5:9232
PMID: 25782665 [PubMed - as supplied by publisher]

Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators.
David G Workman, Andrew Tsatsanis, Frank W Lewis, John P Boyle, Maryam Mousadoust, Nishani T Hettiarachchi, Michael Hunter, Chris S Peers, David Tétard, James A Duce
Metallomics 2015 Mar;
PMID: 25781076 [PubMed - as supplied by publisher]

Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses.
Gerwyn Morris, Michael Berk, Ken Walder, Michael Maes
BMC Med 2015 Dec; 13(1):259
PMID: 25779727 [PubMed - as supplied by publisher]

Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death.
Shaosong Yang, Li Gao, Fangfang Lu, Bao Wang, Fei Gao, Gang Zhu, Zhibiao Cai, Juan Lai, Qian Yang
J Neuroinflammation 2015 Dec; 12(1):258
PMID: 25779444 [PubMed - as supplied by publisher]

Critical issues of the biopsychosocial treatment of Parkinson's disease].
Péter Kincses, Norbert Kovács, Kázmér Karádi, János Kállai
Orv Hetil 2015 Mar; 156(12):472-8
PMID: 25778854 [PubMed - as supplied by publisher]

Extracellular vesicle sorting of ?-Synuclein is regulated by sumoylation.
Marcel Kunadt, Katrin Eckermann, Anne Stuendl, Jing Gong, Belisa Russo, Katrin Strauss, Surya Rai, Sebastian Kügler, Lisandro Falomir Lockhart, Martin Schwalbe, Petranka Krumova, Luis M A Oliveira, Mathias Bähr, Wiebke Möbius, Johannes Levin, Armin Giese, Niels Kruse, Brit Mollenhauer, Ruth Geiss-Friedlander, Albert C Ludolph, Axel Freischmidt, Marisa S Feiler, Karin M Danzer, Markus Zweckstetter, Thomas M Jovin, Mikael Simons, Jochen H Weishaupt, Anja Schneider
Acta Neuropathol 2015 Mar;
PMID: 25778619 [PubMed - as supplied by publisher]

Somatostatin prevents lipopolysaccharide?induced neurodegeneration in the rat substantia nigra by inhibiting the activation of microglia.
Lijuan Bai, Xique Zhang, Xiaohong Li, Na Liu, Fan Lou, Honglei Ma, Xiaoguang Luo, Yan Ren
Mol Med Rep 2015 Mar;
PMID: 25777539 [PubMed - as supplied by publisher]

Epigenetic mechanisms in neurological and neurodegenerative diseases.
Jorge Landgrave-Gómez, Octavio Mercado-Gómez, Rosalinda Guevara-Guzmán
Front Cell Neurosci 2015 ; 9:58
PMID: 25774124 [PubMed - as supplied by publisher]

Dopamine signals and physiological origin of cognitive dysfunction in Parkinson's disease.
Masayuki Matsumoto
Mov Disord 2015 Mar;
PMID: 25773863 [PubMed - as supplied by publisher]

Elucidating the role of site-specific nitration of ?-synuclein in the pathogenesis of Parkinson's disease via protein semisynthesis and mutagenesis.
Ritwik Burai, Nadine Ait-Bouziad, Anass Chiki, Hilal Lashuel
J Am Chem Soc 2015 Mar;
PMID: 25768729 [PubMed - as supplied by publisher]

Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: A multicenter study.
Ronald B Postuma, Alex Iranzo, Birgit Hogl, Isabelle Arnulf, Luigi Ferini-Strambi, Raffaele Manni, Tomoyuki Miyamoto, Wolfgang Oertel, Yves Dauvilliers, Yo-El Ju, Monica Puligheddu, Karel Sonka, Amelie Pelletier, Juan Santamaria, Birgit Frauscher, Smaranda Leu-Semenescu, Marco Zucconi, Michele Terzaghi, Masayuki Miyamoto, Marcus M Unger, Bertrand Carlander, Maria-Livia Fantini, Jacques Y Montplaisir
Ann Neurol 2015 Mar;
PMID: 25767079 [PubMed - as supplied by publisher]

Cerebrospinal fluid concentrations of N-acetylcysteine after oral administration in Parkinson's disease.
Maya Katz, Seok Joon Won, Youngja Park, Adrienne Orr, Dean P Jones, Raymond A Swanson, Graham A Glass
Parkinsonism Relat Disord 2015 Feb;
PMID: 25765302 [PubMed - as supplied by publisher]

The role of L-DOPA in plants.
Anderson Ricardo Soares, Rogério Marchiosi, Rita de Cássia Siqueira-Soares, Rogério Barbosa de Lima, Wanderley Dantas Dos Santos, Osvaldo Ferrarese-Filho
Plant Signal Behav 2014 Apr; 9(4):e28275
PMID: 25764424 [PubMed - as supplied by publisher]

Tool compounds robustly increase turnover of an artificial substrate by glucocerebrosidase in human brain lysates.
Zdenek Berger, Sarah Perkins, Claude Ambroise, Christine Oborski, Matthew Calabrese, Stephen Noell, David Riddell, Warren D Hirst
PLoS One 2015 ; 10(3):e0119141
PMID: 25763858 [PubMed - as supplied by publisher]

Minocycline Rescues from Zinc-Induced Nigrostriatal Dopaminergic Neurodegeneration: Biochemical and Molecular Interventions.
Vinod Kumar, Brajesh Kumar Singh, Amit Kumar Chauhan, Deepali Singh, Devendra Kumar Patel, Chetna Singh
Mol Neurobiol 2015 Mar;
PMID: 25764516 [PubMed - as supplied by publisher]

The Parkinson Disease Mitochondrial Hypothesis: Where Are We at?
Sandra Franco-Iborra, Miquel Vila, Celine Perier
Neuroscientist 2015 Mar;
PMID: 25761946 [PubMed - as supplied by publisher]

Evidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1.
Celia van der Merwe, Zahra Jalali Sefid Dashti, Alan Christoffels, Ben Loos, Soraya Bardien
Eur J Neurosci 2015 Mar;
PMID: 25761903 [PubMed - as supplied by publisher]

On visual hallucinations and cortical networks: a trans-diagnostic review.
Rowena Carter, Dominic H Ffytche
J Neurol 2015 Mar;
PMID: 25761375 [PubMed - as supplied by publisher]

?-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2.
Clive Bate, Alun Williams
Biomolecules 2015 ; 5(1):178-93
PMID: 25761116 [PubMed - as supplied by publisher]

Neuropathologically mixed Alzheimer's and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes.
Lauren Walker, Kirsty E McAleese, Alan J Thomas, Mary Johnson, Carmen Martin-Ruiz, Craig Parker, Sean J Colloby, Kurt Jellinger, Johannes Attems
Acta Neuropathol 2015 Mar;
PMID: 25758940 [PubMed - as supplied by publisher]

Association between Serum Haptoglobin and the Pathogenesis of Alzheimer's Disease.
In-Uk Song, Young-Do Kim, Sung-Woo Chung, Hyun-Ji Cho
Intern Med 2015 ; 54(5):453-7
PMID: 25758069 [PubMed - as supplied by publisher]

Platelet mitochondrial activity and pesticide exposure in early Parkinson's disease.
Jeff M Bronstein, Kimberly Paul, Laurice Yang, Richard H Haas, Clifford W Shults, Thuy Le, Beate Ritz
Mov Disord 2015 Mar;
PMID: 25757798 [PubMed - as supplied by publisher]

Effectiveness of traditional chinese medicine as an adjunct therapy for Parkinson's disease: a systematic review and meta-analysis.
Guoxin Zhang, Nian Xiong, Zhentao Zhang, Ling Liu, Jinsha Huang, Jiaolong Yang, Jing Wu, Zhicheng Lin, Tao Wang
PLoS One 2015 ; 10(3):e0118498
PMID: 25756963 [PubMed - as supplied by publisher]

Changes in retinal function and morphology are early clinical signs of disease in cattle with bovine spongiform encephalopathy.
M Heather West Greenlee, Jodi D Smith, Ekundayo M Platt, Jessica R Juarez, Leo L Timms, Justin J Greenlee
PLoS One 2015 ; 10(3):e0119431
PMID: 25756286 [PubMed - as supplied by publisher]

Distinctive Features of NREM Parasomnia Behaviors in Parkinson's Disease and Multiple System Atrophy.
Pietro-Luca Ratti, Maria Sierra-Peńa, Raffaele Manni, Marion Simonetta-Moreau, Julien Bastin, Harrison Mace, Olivier Rascol, Olivier David
PLoS One 2015 ; 10(3):e0120973
PMID: 25756280 [PubMed - as supplied by publisher]

The N?Terminus of ?-Synuclein Forms Cu(II) -Bridged Oligomers.
Simon C Drew
Chemistry 2015 Mar;
PMID: 25757154 [PubMed - as supplied by publisher]

Conformational dynamics of ?-synuclein: insights from mass spectrometry.
Ashley S Phillips, Alexandre F Gomes, Jason M D Kalapothakis, Jay E Gillam, Jonas Gasparavicius, Fabio C Gozzo, Tilo Kunath, Cait MacPhee, Perdita E Barran
Analyst 2015 Mar;
PMID: 25756329 [PubMed - as supplied by publisher]

Novel subcellular localization for ?-synuclein: possible functional consequences.
Cristina Guardia-Laguarta, Estela Area-Gomez, Eric A Schon, Serge Przedborski
Front Neuroanat 2015 ; 9:17
PMID: 25755636 [PubMed - as supplied by publisher]

Serum peptides as candidate biomarkers for dementia with Lewy bodies.
Itsuku Suzuki, Miwa Noguchi, Mitsumi Arito, Toshiyuki Sato, Kazuki Omoteyama, Mioto Maedomari, Hiroshi Hasegawa, Naoya Suematsu, Kazuki Okamoto, Tomohiro Kato, Noboru Yamaguchi, Manae S Kurokawa
Int J Geriatr Psychiatry 2015 Mar;
PMID: 25754375 [PubMed - as supplied by publisher]

Convergence and divergence of genetic and modular networks between diabetes and breast cancer.
Xiaoxu Zhang, Yingying Zhang, Yanan Yu, Jun Liu, Ye Yuan, Yijun Zhao, Haixia Li, Jie Wang, Zhong Wang
J Cell Mol Med 2015 Mar;
PMID: 25752479 [PubMed - as supplied by publisher]

The avascular zone and neuronal remodeling of the fovea in Parkinson disease.
Shahnaz Miri, Eric M Shrier, Sofya Glazman, Yin Ding, Ivan Selesnick, Piotr B Kozlowski, Ivan Bodis-Wollner
Ann Clin Transl Neurol 2015 Feb; 2(2):196-201
PMID: 25750923 [PubMed - as supplied by publisher]

Mitochondrial mechanisms of redox cycling agents implicated in Parkinson's disease.
Pamela Lopert, Manisha Patel
J Neural Transm 2015 Mar;
PMID: 25749885 [PubMed - as supplied by publisher]

The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging.
William K Gottschalk, Michael W Lutz, Yu Ting He, Ann M Saunders, Daniel K Burns, Allen D Roses, Ornit Chiba-Falek
J Parkinsons Dis Alzheimers Dis 2014 Nov; 1(1)
PMID: 25745640 [PubMed - as supplied by publisher]

Imaging Amyloidopathy in Parkinson Disease and Parkinsonian Dementia Syndromes.
Kirk A Frey, Myria Petrou
Clin Transl Imaging 2015 Feb; 3(1):57-64
PMID: 25745616 [PubMed - as supplied by publisher]

The contribution of mitochondria to sensory processing and pain.
Sarah J L Flatters
Prog Mol Biol Transl Sci 2015 ; 131:119-46
PMID: 25744672 [PubMed - as supplied by publisher]