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Featured Research

What can we learn by studying exercise and Parkinson's? PDF-funded researcher Kristen Pickett, Ph.D., is using magnetic resonance imaging to help find answers to improve life for people with PD.

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PDF Grant Programs

Are you interested in furthering Parkinson's science? View PDF's open grant programs.

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Causes and Pathology

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.


Prevención de Caídas

1) PDF Research Centers

Columbia


http://www.ncbi.nlm.nih.gov/pubmed?term=Columbia%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(alcalay%20rn%5Bau%5D%20OR%20burke%20rb%5BAU%5D%20OR%20clark%20l%5BAU%5D%20OR%20fahn%20s%5BAU%5D%20OR%20Ford%20B%5BAU%5D%20OR%20greene%20l%5BAU%5D%20OR%20greene%20p%5BAU%5D%20OR%20kuo%20sh%5Bau%5D%20OR%20louis%20e%5BAU%5D%20OR%20marder%20k%5BAU%5D%20OR%20mazzoni%20p%5BAU%5D%20OR%20przedborski%20s%5BAU%5D%20OR%20pullman%20s%5BAU%5D%20OR%20stern%20y%5BAU%5D%20OR%20sulzer%20d%5BAU%5D%20OR%20vonsattel%5BAU%5D%20OR%20waters%20c%5BAU%5D%20OR%20yamamoto%20a%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Rush


http://www.ncbi.nlm.nih.gov/pubmed?term=Rush%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Barton%20B%5BAU%5D%20OR%20Bernard%20B%5BAU%5D%20OR%20Comella%20C%5BAU%5D%20OR%20Goldman%20J%5BAU%5D%20OR%20Goetz%20C%5BAU%5D%20OR%20Hall%20D%5BAU%5D%20OR%20Kompoliti%20K%5BAU%5D%20OR%20Kordower%20J%5BAU%5D%20OR%20Shannon%20K%5BAU%5D%20Stebbins%20G%5BAU%5D%20OR%20Verhagen%20L%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Cornell


http://www.ncbi.nlm.nih.gov/pubmed?term=Cornell%5BAD%5D%20AND%20(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Beal%20MF%5BAU%5D%20OR%20Henchcliffe%20c%5BAU%5D%20OR%20Nirenberg%20m%5BAU%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

PARKINSON’S DISEASE TOPIC AREAS
Understanding Parkinson’s


Motor Symptoms
    

General

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(motor%5BAll%20Fields%5D%20AND%20(%22diagnosis%22%5BSubheading%5D%20OR%20%22diagnosis%22%5BAll%20Fields%5D%20OR%20%22symptoms%22%5BAll%20Fields%5D%20OR%20%22diagnosis%22%5BMeSH%20Terms%5D%20OR%20%22symptoms%22%5BAll%20Fields%5D))%20NOT%20(%E2%80%9Cnon-motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnon%20motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnonmotor%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)%20AND%20(%22review%22%5BPublication%20Type%5D%20OR%20%22review%20literature%20as%20topic%22%5BMeSH%20Terms%5D%20OR%20%22review%22%5BAll%20Fields%5D)

    Balance and Falls

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Balance%20%5BTIAB%5D%20OR%20Falls%20%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)
    Gait or Freezing

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Gait%5BTIAB%5D%20OR%20Freezing%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Dyskinesia
    Nonmotor Symptoms and Complications

    General
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(%E2%80%9Cnon-motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnon%20motor%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9Cnonmotor%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Pain
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(pain%5BTI%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Sleep and Fatigue/ REM Behavior Sleep Disorder

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Sleep%5BTIAB%5D%20OR%20Fatigue%5BTIAB%5D%20OR%20%E2%80%9DREM%20behavior%20disorder%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Gastrointestinal and Urinary Function
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Gastrointestinal%5BTIAB%5D%20OR%20Urinary%20%5BTIAB%5D%20OR%20%E2%80%9CBowel%20dysfunction%E2%80%9D%5BTIAB%5D%20OR%20%E2%80%9CBladder%20dysfunction%E2%80%9D%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Cognition and Hallucination

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(cognition%5BTIAB%5D%20OR%20hallucination%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Impulse Control Disorder

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Impulse%20Control%20Disorder%5BTIAB%5D%20OR%20ICD%5BTIAB%5D%20OR%20gambling%5BTIAB%5D%20OR%20shopping%5BTIAB%5D%20OR%20hypersexuality%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Vision/Visual hallucination

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Blurred%20vision%5BTIAB%5D%20OR%20Photophobia%5BTIAB%5D%20OR%20Asthenopia%5BTIAB%5D%20OR%20Double%20vision%5BTIAB%5D%20OR%20Visual%20hallucination%5BTIAB%5D%20OR%20spatial%20relations%5BTIAB%5D%20OR%20color%20perception%5BTIAB%5D)

Oral
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(dental%5BTIAB%5D%20OR%20dysphagia%5BTIAB%5D%20OR%20burning%20mouth%5BTIAB%5D%20OR%20drooling%5BTIAB%5D%20OR%20teeth%5BTIAB%5D%20or%20sialorrhea%5BTIAB%5D%20OR%20gingiva%5BTIAB%5D%20OR%20periodontal%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Speech
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(speech%5BTIAB%5D%20OR%20hypophonia%5BTIAB%5D%20OR%20verbal%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Orthostatic Hypotension
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(Orthostatic%20Hypotension%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Etiology/Pathology

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(etiology%5BTIAB%5D%20OR%20pathology%5BTIAB%5D%20OR%20disease%20model%5BTIAB%5D)%20AND%20(%22review%22%5BPublication%20Type%5D%20OR%20%22review%20literature%20as%20topic%22%5BMeSH%20Terms%5D%20OR%20%22review%22%5BAll%20Fields%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Imaging Studies
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(imaging%5BTIAB%5D%20OR%20MRI%5BTIAB%5D%20OR%20fMRI%5BTIAB%5D%20OR%20PET%5BTIAB%5D%20OR%20SPECT%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Clinical Studies

General
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20Clinical%20Trial%5Bptyp%5D%20AND%20(%22last%20180%20days%22%5BDP%5D)

Genetics

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(%22genetics%22%5BSubheading%5D%20OR%20%22genetics%22%5BAll%20Fields%5D%20OR%20%22genetics%22%5BMeSH%20Terms%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Treating Parkinson’s

Current and potential medications/Therapies http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(treatment%5BTI%5D%20OR%20therapy%5BTI%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

    Surgical Treatments
        
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(stem%20cell%5BTIAB%5D)%20AND%20(treatment%5BTIAB%5D%20OR%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)
    
Gene Therapy
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(gene%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Deep Brain Stimulation
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(gene%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Physical, Occupational and Speech Therapy
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(physical%20therapy%5BTIAB%5D%20OR%20occupational%20therapy%5BTIAB%5D%20OR%20speech%20therapy%5BTIAB%5D%20OR%20rehabilitation%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Nutrition

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(diet%5Btiab%5D%20OR%20nutrition%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Exercise
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(exercise%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Art and Music

http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(art%5BTIAB%5D%20OR%20painting%5BTIAB%5D%20OR%20creativity%5BTIAB%5DOR%20music%5BTIAB%5D)%20NOT%20%E2%80%9Cstate%20of%20the%20art%E2%80%9D%5BTIAB%5D%20AND%20(%22last%2090%20days%22%5BDP%5D)


Complementary and Alternative Therapies
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(complementary%20therapy%5BTIAB%5D%20OR%20alternative%20therapy%5BTIAB%5D%20OR%20Adjunct%20therapy%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)


Living with a Parkinson’s Diagnosis

Driving
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(driving%5BTIAB%5D%20AND%20(car%5BTIAB%5D%20OR%20automobile%5BTIAB%5D))

Hospitalization


http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(hospitalization%5BTIAB%5D)%20AND%20(%22last%2090%20days%22%5BDP%5D)

Care giving
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(caregiver%5BTIAB%5D%20OR%20caregiving%5BTIAB%5D%20OR%20hygiene%5BTIAB%5D%20OR%20dressing%5BTIAB%5D%20OR%20support%20group%5BTIAB%5D%20OR%20health%20care%5BTIAB%5D%20OR%20home%20care%5BTIAB%5D%20OR%20helpline%5BTIAB%5D)AND%20(%22last%2090%20days%22%5BDP%5D)

Hospice/End of Life/Palliative Care
http://www.ncbi.nlm.nih.gov/pubmed?term=(Parkinson%5BTIAB%5D%20OR%20Parkinson%E2%80%99s%20disease%5BTIAB%5D)%20AND%20(hospice%5BTI%5D%20OR%20%E2%80%9Cend%20of%20life%E2%80%9D%5BTI%5D%20OR%20palliative%5BTI%5D)

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Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies.
Davide Chiasserini, Silvia Paciotti, Paolo Eusebi, Emanuele Persichetti, Anna Tasegian, Marzena Kurzawa-Akanbi, Patrick F Chinnery, Christopher M Morris, Paolo Calabresi, Lucilla Parnetti, Tommaso Beccari
Mol Neurodegener 2015 Mar; 10(1):15
PMID: 25881142 [PubMed - as supplied by publisher]


Amyloid deposition in Parkinson's disease and cognitive impairment: A systematic review.
Myria Petrou, Ben A Dwamena, Bradley R Foerster, Mark P MacEachern, Nicolaas I Bohnen, Martijn Ltm Müller, Roger L Albin, Kirk A Frey
Mov Disord 2015 Apr;
PMID: 25879534 [PubMed - as supplied by publisher]


Overexpression of 17?-hydroxysteroid dehydrogenase type 10 increases pheochromocytoma cell growth and resistance to cell death.
Emily A Carlson, Rebecca T Marquez, Fang Du, Yongfu Wang, Liang Xu, Shirley ShiDu Yan
BMC Cancer 2015; 15(1):166
PMID: 25879199 [PubMed - as supplied by publisher]


RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.
Núria Martín-Flores, Joan Romaní-Aumedes, Laura Rué, Mercè Canal, Phil Sanders, Marco Straccia, Nicholas D Allen, Jordi Alberch, Josep M Canals, Esther Pérez-Navarro, Cristina Malagelada
Mol Neurobiol 2015 Apr;
PMID: 25876513 [PubMed - as supplied by publisher]


Neuroprotective Effects of the Cultivated Chondrus crispus in a C. elegans Model of Parkinson's Disease.
Jinghua Liu, Arjun H Banskota, Alan T Critchley, Jeff Hafting, Balakrishnan Prithiviraj
Mar Drugs 2015 ; 13(4):2250-66
PMID: 25874922 [PubMed - as supplied by publisher]


Exosomes as drug delivery vehicles for Parkinson's disease therapy.
Matthew J Haney, Natalia L Klyachko, Yuling Zhao, Richa Gupta, Evgeniya G Plotnikova, Zhijian He, Tejash Patel, Aleksandr Piroyan, Marina Sokolsky, Alexander V Kabanov, Elena V Batrakova
J Control Release 2015 Mar; 207:18-30
PMID: 25836593 [PubMed - as supplied by publisher]


Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions.
Jason M Hinzman, Vince A DiNapoli, Eric J Mahoney, Greg A Gerhardt, Jed A Hartings
Exp Neurol 2015 Mar; 267:243-253
PMID: 25819105 [PubMed - as supplied by publisher]


Acrylamide induces locomotor defects and degeneration of dopamine neurons in Caenorhabditis elegans.
Jia Li, Dan Li, Yongsheng Yang, Tiantian Xu, Ping Li, Defu He
J Appl Toxicol 2015 Apr;
PMID: 25876170 [PubMed - as supplied by publisher]


The Interplay between Alpha-Synuclein Clearance and Spreading.
Tomás Lopes da Fonseca, Anna Villar-Piqué, Tiago Fleming Outeiro
Biomolecules 2015; 5(2):435-471
PMID: 25874605 [PubMed - as supplied by publisher]


Loss of hfe function reverses impaired recognition memory caused by olfactory manganese exposure in mice.
Qi Ye, Jonghan Kim
Toxicol Res 2015 Mar; 31(1):17-23
PMID: 25874029 [PubMed - as supplied by publisher]


Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated ?-synuclein.
Eduard Bentea, Anke Van der Perren, Joeri Van Liefferinge, Anissa El Arfani, Giulia Albertini, Thomas Demuyser, Ellen Merckx, Yvette Michotte, Ilse Smolders, Veerle Baekelandt, Ann Massie
Front Behav Neurosci 2015 ; 9:68
PMID: 25873870 [PubMed - as supplied by publisher]


Proof of concept studies exploring the safety and functional activity of human parthenogenetic-derived neural stem cells for the treatment of Parkinson's disease.
Rodolfo Gonzalez, Ibon Garitaonandia, Andrew Crain, Maxim Poustovoitov, Tatiana Abramihina, Alexander Noskov, Chuan Jiang, Robert Morey, Louise C Laurent, John D Elsworth, Evan Y Snyder, D Eugene Redmond, Ruslan Semechkin
Cell Transplant 2015 ; 24(4):681-90
PMID: 25839189 [PubMed - as supplied by publisher]


?-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation.
Shijun Wang, Chun-Hsien Chu, Tessandra Stewart, Carmen Ginghina, Yifei Wang, Hui Nie, Mingri Guo, Belinda Wilson, Jau-Shyong Hong, Jing Zhang
Proc Natl Acad Sci U S A 2015 Apr; 112(15):E1926-35
PMID: 25825709 [PubMed - as supplied by publisher]


Ser129 phosphorylation of endogenous ?-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.
Kerstin Buck, Natalie Landeck, Ayse Ulusoy, Nour K Majbour, Omar M A El-Agnaf, Deniz Kirik
Neurobiol Dis 2015 Mar; 78:100-114
PMID: 25818009 [PubMed - as supplied by publisher]


Alpha-synucleinopathy and neuropsychological symptoms in a population-based cohort of the elderly.
Julia Zaccai, Carol Brayne, Fiona E Matthews, Paul G Ince,
Alzheimers Res Ther 2015 ; 7(1):19
PMID: 25870655 [PubMed - as supplied by publisher]


The role of the acidic domain of ?-synuclein in amyloid fibril formation: A molecular dynamics study.
SeongByeong Park, Jeseong Yoon, Soonmin Jang, Kyunghee Lee, Seokmin Shin
J Biomol Struct Dyn 2015 Apr; :1-25
PMID: 25869255 [PubMed - as supplied by publisher]


A tripeptide isolated from Bothrops atrox venom has neuroprotective and neurotrophic effects on a cellular model of Parkinson's disease.
N M Martins, N A G Santos, M A Sartim, A C O Cintra, S V Sampaio, A C Santos
Chem Biol Interact 2015 Apr;
PMID: 25868679 [PubMed - as supplied by publisher]


Glutathione S-transferase T1 and M1 null genotypes and Parkinson's disease risk: evidence from an updated meta-analysis.
Hongzhou Liu, Jie Peng, Jiajia Gao, Fang Zheng, Chaorong Tie
Neurol Sci 2015 Apr;
PMID: 25868597 [PubMed - as supplied by publisher]


The prion hypothesis of Parkinson's disease.
Yaping Chu, Jeffrey H Kordower
Curr Neurol Neurosci Rep 2015 May; 15(5):549
PMID: 25868519 [PubMed - as supplied by publisher]


CK2beta promotes Pink1/Parkin-mediated MIRO1 degradation].
Chenliang Zhang, Siyue Qin, Chang'an Jiang
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2014 Dec; 31(6):1310-5
PMID: 25868250 [PubMed - as supplied by publisher]


Delayed emergence from general anesthesia in a dementia patient with Lewy bodies].
Sawako Takebe, Kazuyoshi Inoue, Hiroyuki Kawanishi, Hitoshi Nakamura, Ai Ohnishi, Junji Ohnishi, Yuichi Yatsu, Akihiro Nagai, Rikiya Matsuda, Akihito Hirasaki
Masui 2015 Jan; 64(1):81-3
PMID: 25868207 [PubMed - as supplied by publisher]


Serotonin6 receptors in the dorsal hippocampus regulate depressive-like behaviors in unilateral 6-hydroxydopamine-lesioned Parkinson's rats.
Kun-Cheng Liu, Jun-Yi Li, Hui-Hui Tan, Cheng-Xue Du, Wen Xie, Yu-Ming Zhang, Wei-Lin Ma, Li Zhang
Neuropharmacology 2015 Apr;
PMID: 25863121 [PubMed - as supplied by publisher]


Increased 14-3-3 phosphorylation observed in Parkinson's disease reduces neuroprotective potential of 14-3-3 proteins.
Sunny Rae Slone, Nicholas Lavalley, Michael McFerrin, Bing Wang, Talene Alene Yacoubian
Neurobiol Dis 2015 Apr;
PMID: 25862939 [PubMed - as supplied by publisher]


Phosphorylated ubiquitin chain is the genuine Parkin receptor.
Kei Okatsu, Fumika Koyano, Mayumi Kimura, Hidetaka Kosako, Yasushi Saeki, Keiji Tanaka, Noriyuki Matsuda
J Cell Biol 2015 Apr; 209(1):111-28
PMID: 25847540 [PubMed - as supplied by publisher]


The effects of neuropeptide urocortin 2 on the spontaneous discharge and glutamatergic neurotransmission of striatum neurons.
Chunna Liu, Xinyu Liu, Feiran Song, Jian Li, Xia Zhang, Jing Yang
Neuropeptides 2015 Apr; 50:17-21
PMID: 25837973 [PubMed - as supplied by publisher]


Rapid Eye Movement Sleep Behavior Disorder and Neurodegenerative Disease.
Michael Joseph Howell, Carlos Hugh Schenck
JAMA Neurol 2015 Apr;
PMID: 25867792 [PubMed - as supplied by publisher]


High levels of DJ-1 protein and isoelectric point 6.3 isoform in the serum of breast cancer patients.
Takahiko Kawate, Keiichi Iwaya, Kayoko Koshikawa, Tomoyuki Moriya, Tamio Yamasaki, Sho Hasegawa, Hiroshi Kaise, Tomoyuki Fujita, Hirotaka Matsuo, Takahiro Nakamura, Takashi Ishikawa, Sadayuki Hiroi, Sanae M M Iguchi-Ariga, Hiroyoshi Ariga, Keiichi Murota, Minoru Fujimori, Junji Yamamoto, Osamu Matsubara, Norio Kohno
Cancer Sci 2015 Apr;
PMID: 25867058 [PubMed - as supplied by publisher]


Could ?-Synuclein Amyloid-Like Aggregates Trigger a Prionic Neuronal Invasion?
Maria Antònia Busquets, Alba Espargaró, Joan Estelrich, Raimon Sabate
Biomed Res Int 2015; 2015:172018
PMID: 25866763 [PubMed - as supplied by publisher]


Chaperoned amyloid proteins for immune manipulation: ?-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype.
Adahir Labrador-Garrido, Marta Cejudo-Guillén, Rebecca Klippstein, Erwin J De Genst, Laura Tomas-Gallardo, María M Leal, Javier Villadiego, Juan J Toledo-Aral, Christopher M Dobson, David Pozo, Cintia Roodveldt
Immun Inflamm Dis 2014 Dec; 2(4):226-38
PMID: 25866630 [PubMed - as supplied by publisher]


Reactivity of copper-?-synuclein peptide complexes relevant to Parkinson's disease.
Simone Dell'Acqua, Valentina Pirota, Cecilia Anzani, Michela M Rocco, Stefania Nicolis, Daniela Valensin, Enrico Monzani, Luigi Casella
Metallomics 2015 Apr;
PMID: 25865825 [PubMed - as supplied by publisher]


Neuroimaging and traumatic brain injury: State of the field and voids in translational knowledge.
Erica D Bruce, Sneha Konda, Dana D Dean, Ernest W Wang, Jason H Huang, Deborah M Little
Mol Cell Neurosci 2015 Mar;
PMID: 25827094 [PubMed - as supplied by publisher]


Pareidolia in Parkinson's disease without dementia: A positron emission tomography study.
Makoto Uchiyama, Yoshiyuki Nishio, Kayoko Yokoi, Yoshiyuki Hosokai, Atsushi Takeda, Etsuro Mori
Parkinsonism Relat Disord 2015 Mar;
PMID: 25864093 [PubMed - as supplied by publisher]


The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (?-syn) toxicity to rat nigral neurons.
Maxim Salganik, Valeriy G Sergeyev, Vishal Shinde, Craig A Meyers, Marina S Gorbatyuk, Jonathan H Lin, Sergey Zolotukhin, Oleg S Gorbatyuk
Neurobiol Aging 2015 Mar;
PMID: 25863526 [PubMed - as supplied by publisher]


Convergence of parkin, PINK1 and ?-synuclein on stress-induced mitochondrial morphological remodelling.
Kristi L Norris, Rui Hao, Liang-Fu Chen, Chun-Hsiang Lai, Meghan Kapur, Peter J Shaughnessy, Dennis Chou, Jin Yan, J Paul Taylor, Simone Engelender, Anna E West, Kah-Leong Lim, Tso-Pang Yao
J Biol Chem 2015 Apr;
PMID: 25861987 [PubMed - as supplied by publisher]


Mitochondrial dynamism and heart disease: changing shape and shaping change.
Gerald W Dorn
EMBO Mol Med 2015 Apr;
PMID: 25861797 [PubMed - as supplied by publisher]


Alpha-synuclein modulates NR2B-containing NMDA receptors and decreases their levels after rotenone exposure.
Laura Navarria, Michela Zaltieri, Francesca Longhena, Maria Grazia Spillantini, Cristina Missale, PierFranco Spano, Arianna Bellucci
Neurochem Int 2015 Apr;
PMID: 25846226 [PubMed - as supplied by publisher]


Neurotensinergic augmentation of glutamate release at the perforant path-granule cell synapse in rat dentate gyrus: Roles of L-Type Ca(2+) channels, calmodulin and myosin light-chain kinase.
Haopeng Zhang, Hailong Dong, Saobo Lei
Neuropharmacology 2015 Apr;
PMID: 25842242 [PubMed - as supplied by publisher]


Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with ?-synucleinopathies.
R T Bartus, J H Kordower, E M Johnson, L Brown, B R Kruegel, Y Chu, T L Baumann, A E Lang, C W Olanow, C D Herzog
Neurobiol Dis 2015 Apr;
PMID: 25841760 [PubMed - as supplied by publisher]


Folic acid supplementation rescues anomalies associated with knockdown of parkin in dopaminergic and serotonergic neurons in Drosophila model of Parkinson's disease.
Saurabh Srivastav, Sandeep Kumar Singh, Amarish Kumar Yadav, Saripella Srikrishna
Biochem Biophys Res Commun 2015 Mar;
PMID: 25824034 [PubMed - as supplied by publisher]


Prolongation of Chemically-Induced Methemoglobinemia in Mice Lacking ?-synuclein: A Novel Pharmacologic and Toxicologic Phenotype.
Yien-Ming Kuo, Robert L Nussbaum
Toxicol Rep 2015; 2:504-511
PMID: 25859428 [PubMed - as supplied by publisher]


Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection.
Mark W Pellegrino, Cole M Haynes
BMC Biol 2015 ; 13(1):22
PMID: 25857750 [PubMed - as supplied by publisher]


Zonisamide reduces nigrostriatal dopaminergic neurodegeneration in a mouse genetic model of Parkinson's disease.
Hiromi Sano, Miho Murata, Atsushi Nambu
J Neurochem 2015 Apr;
PMID: 25857446 [PubMed - as supplied by publisher]


Ferulic acid pretreatment mitigates MPTP-induced motor impairment and histopathological alterations in C57BL/6 mice.
Sangeetha Nagarajan, David Raj Chellappan, Prabu Chinnaswamy, Senthilkumar Thulasingam
Pharm Biol 2015 Apr; :1-11
PMID: 25857436 [PubMed - as supplied by publisher]


Neuroprotective effects of alkaloids from Piper longum in a MPTP-induced mouse model of Parkinson's disease.
Ying Bi, Peng-Cheng Qu, Qing-Song Wang, Li Zheng, Hao-Long Liu, Rong Luo, Xiao-Qing Chen, Yin-Ying Ba, Xia Wu, Hui Yang
Pharm Biol 2015 Apr; :1-9
PMID: 25857256 [PubMed - as supplied by publisher]


Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses.
Gerwyn Morris, Michael Berk, Ken Walder, Michael Maes
BMC Med 2015 ; 13(1):28
PMID: 25856766 [PubMed - as supplied by publisher]


Role of the unfolded protein response in the pathogenesis of Parkinson's disease.
Deeksha Varma, Dwaipayan Sen
Acta Neurobiol Exp (Wars) 2015 ; 75(1):1-26
PMID: 25856519 [PubMed - as supplied by publisher]


Small Peptide Inhibitor of JNK3 Protects Dopaminergic Neurons from MPTP Induced Injury via Inhibiting the ASK1-JNK3 Signaling Pathway.
Jing Pan, Hui Li, Bei Zhang, Ran Xiong, Yu Zhang, Wen-Yan Kang, Wei Chen, Zong-Bo Zhao, Sheng-Di Chen
PLoS One 2015 ; 10(4):e0119204
PMID: 25856433 [PubMed - as supplied by publisher]


Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock in mice.
M Yue, K Hinkle, P Davies, E Trushina, F Fiesel, T Christenson, A Schroeder, L Zhang, E Bowles, B Behrouz, S Lincoln, J Beevers, A Milnerwood, A Kurti, P J McLean, J D Fryer, W Springer, D Dickson, M Farrer, H Melrose
Neurobiol Dis 2015 Mar;
PMID: 25836420 [PubMed - as supplied by publisher]


?-Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2.
Lauren R Kett, Barbara Stiller, Megan M Bernath, Inmaculada Tasset, Javier Blesa, Vernice Jackson-Lewis, Robin B Chan, Bowen Zhou, Gilbert Di Paolo, Serge Przedborski, Ana Maria Cuervo, William T Dauer
J Neurosci 2015 Apr; 35(14):5724-42
PMID: 25855184 [PubMed - as supplied by publisher]


E-health Support in People with Parkinson's Disease with Smart Glasses: A Survey of User Requirements and Expectations in the Netherlands.
Yan Zhao, Tjitske Heida, Erwin E H van Wegen, Bastiaan R Bloem, Richard J A van Wezel
J Parkinsons Dis 2015 Apr;
PMID: 25855044 [PubMed - as supplied by publisher]


Minimal change multiple system atrophy: An aggressive variant?
Helen Ling, Yasmine T Asi, Igor N Petrovic, Zeshan Ahmed, L K Prashanth, Lili-Naz Hazrati, Masatoyo Nishizawa, Tetsutaro Ozawa, Anthony Lang, Andrew J Lees, Tamas Revesz, Janice L Holton
Mov Disord 2015 Apr;
PMID: 25854893 [PubMed - as supplied by publisher]


Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate.
Petranka Krumova, Lauran Reyniers, Marc Meyer, Evy Lobbestael, Daniela Stauffer, Bertran Gerrits, Lionel Muller, Sjouke Hoving, Klemens Kaupmann, Johannes Voshol, Doriano Fabbro, Andreas Bauer, Giorgio Rovelli, Jean-Marc Taymans, Tewis Bouwmeester, Veerle Baekelandt
FASEB J 2015 Apr;
PMID: 25854701 [PubMed - as supplied by publisher]


PGC-1? activity in nigral dopamine neurons determines vulnerability to ?-synuclein.
Carine Ciron, Lu Zheng, Wojciech Bobela, Graham W Knott, Teresa C Leone, Daniel P Kelly, Bernard L Schneider
Acta Neuropathol Commun 2015 ; 3(1):16
PMID: 25853296 [PubMed - as supplied by publisher]


Individual differences in approach-avoidance aptitude: some clues from research on Parkinson's disease.
Alberto Costa, Carlo Caltagirone
Front Syst Neurosci 2015 ; 9:43
PMID: 25852500 [PubMed - as supplied by publisher]


Neuroprotective effects of paeonol in a cell model of Parkinson disease].
Hao Wang, Zhao-Ming Geng, Zhi-Wei Hu, Shu-Yan Wang, Bing Zhao
Zhejiang Da Xue Xue Bao Yi Xue Ban 2015 Jan; 44(1):30-6
PMID: 25851972 [PubMed - as supplied by publisher]


Use of CSF ?-synuclein in the differential diagnosis between Alzheimer's disease and other neurodegenerative disorders.
Zheng-Yu Wang, Zhen-Min Han, Qi-Fei Liu, Wei Tang, Kui Ye, Yu-You Yao
Int Psychogeriatr 2015 Apr; :1-10
PMID: 25851548 [PubMed - as supplied by publisher]


Structural characterisation of high order alpha-synuclein oligomers capable of inducing intracellular aggregation.
Eva Illes-Toth, Mafalda Ribeiro Ramos, Roberto Cappai, Caroline Dalton, David Paul Smith
Biochem J 2015 Apr;
PMID: 25851527 [PubMed - as supplied by publisher]


Safinamide: First Global Approval.
Emma D Deeks
Drugs 2015 Apr;
PMID: 25851099 [PubMed - as supplied by publisher]


The endoplasmic reticulum/mitochondria interface: a subcellular platform for the orchestration of the functions of the PINK1-Parkin pathway?
Zoi Erpapazoglou, Olga Corti
Biochem Soc Trans 2015 Apr; 43(2):297-301
PMID: 25849933 [PubMed - as supplied by publisher]


Linking microtubules to Parkinson's disease: the case of parkin.
Graziella Cappelletti, Francesca Casagrande, Alessandra Calogero, Carmelita De Gregorio, Gianni Pezzoli, Daniele Cartelli
Biochem Soc Trans 2015 Apr; 43(2):292-6
PMID: 25849932 [PubMed - as supplied by publisher]


Biochemical properties of the kinase PINK1 as sensor protein for mitochondrial damage signalling.
Cornelia Rüb, Nadja Schröder, Wolfgang Voos
Biochem Soc Trans 2015 Apr; 43(2):287-91
PMID: 25849931 [PubMed - as supplied by publisher]


PINK1 activation-turning on a promiscuous kinase.
Liesbeth Aerts, Bart De Strooper, Vanessa A Morais
Biochem Soc Trans 2015 Apr; 43(2):280-6
PMID: 25849930 [PubMed - as supplied by publisher]


Decrease in Plasma Levels of ?-Synuclein Is Evident in Patients with Parkinson's Disease after Elimination of Heterophilic Antibody Interference.
Ryotaro Ishii, Takahiko Tokuda, Harutsugu Tatebe, Takuma Ohmichi, Takashi Kasai, Masanori Nakagawa, Toshiki Mizuno, Omar M A El-Agnaf
PLoS One 2015 ; 10(4):e0123162
PMID: 25849645 [PubMed - as supplied by publisher]


Leaky intestine and impaired microbiome in an amyotrophic lateral sclerosis mouse model.
Shaoping Wu, Jianxun Yi, Yong-Guo Zhang, Jingsong Zhou, Jun Sun
Physiol Rep 2015 Apr; 3(4)
PMID: 25847918 [PubMed - as supplied by publisher]


Cognitive and affective theory of mind in Lewy body dementia: A preliminary study].
C Heitz, N Vogt, B Cretin, N Philippi, B Jung, C Phillipps, F Blanc
Rev Neurol (Paris) 2015 Apr;
PMID: 25847396 [PubMed - as supplied by publisher]


TDP-43 in amyotrophic lateral sclerosis - is it a prion disease?
A C Ludolph, J Brettschneider
Eur J Neurol 2015 May; 22(5):753-61
PMID: 25846565 [PubMed - as supplied by publisher]


Distinct Role of Hydration Water in Protein Misfolding and Aggregation Revealed by Fluctuating Thermodynamics Analysis.
Song-Ho Chong, Sihyun Ham
Acc Chem Res 2015 Apr;
PMID: 25844814 [PubMed - as supplied by publisher]


Mitochondrial Alterations by PARKIN in Dopaminergic Neurons Using PARK2 Patient-Specific and PARK2 Knockout Isogenic iPSC Lines.
Atossa Shaltouki, Renuka Sivapatham, Ying Pei, Akos A Gerencser, Olga Mom?ilovi?, Mahendra S Rao, Xianmin Zeng
Stem Cell Reports 2015 Apr;
PMID: 25843045 [PubMed - as supplied by publisher]


PET/MR in Dementia and Other Neurodegenerative Diseases.
Henryk Barthel, Matthias L Schroeter, Karl-Titus Hoffmann, Osama Sabri
Semin Nucl Med 2015 May; 45(3):224-233
PMID: 25841277 [PubMed - as supplied by publisher]


DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease.
Kazuko Takahashi-Niki, Ayako Inafune, Naruyuki Michitani, Yoshitaka Hatakeyama, Kotaro Suzuki, Mai Sasaki, Yoshihisa Kitamura, Takeshi Niki, Sanae M M Iguchi-Ariga, Hiroyoshi Ariga
J Pharmacol Sci 2015 Mar; 127(3):305-10
PMID: 25837927 [PubMed - as supplied by publisher]


Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein.
Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi
PLoS Genet 2015 Apr; 11(4):e1005065
PMID: 25835295 [PubMed - as supplied by publisher]


Glycogen synthase kinase-3 beta (GSK-3?) signaling: Implications for Parkinson's disease.
Mojtaba Golpich, Elham Amini, Fatemeh Hemmati, Norlinah Mohamed Ibrahim, Behrouz Rahmani, Zahurin Mohamed, Azman Ali Raymond, Leila Dargahi, Rasoul Ghasemi, Abolhassan Ahmadiani
Pharmacol Res 2015 Mar;
PMID: 25829335 [PubMed - as supplied by publisher]


Mini review: linkage between ?-Synuclein protein and cognition.
Huda Saleh, Ayeh Saleh, Hailan Yao, Jie Cui, Yong Shen, Rena Li
Transl Neurodegener 2015 ; 4:5
PMID: 25834729 [PubMed - as supplied by publisher]


Definition of a Molecular Pathway Mediating ?-Synuclein Neurotoxicity.
Jacqueline Burré, Manu Sharma, Thomas C Südhof
J Neurosci 2015 Apr; 35(13):5221-32
PMID: 25834048 [PubMed - as supplied by publisher]


Agonists of the tissue-protective erythropoietin receptor in the treatment of Parkinson's disease.
Juha Punnonen, James L Miller, Timothy J Collier, Jeffrey R Spencer
Curr Top Med Chem 2015 ; 15(10):955-69
PMID: 25832721 [PubMed - as supplied by publisher]


Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF.
Roman Fischer, Olaf Maier
Oxid Med Cell Longev 2015; 2015:610813
PMID: 25834699 [PubMed - as supplied by publisher]


?-Synuclein Over-Expression Induces Increased Iron Accumulation and Redistribution in Iron-Exposed Neurons.
Richard Ortega, Asuncion Carmona, Stéphane Roudeau, Laura Perrin, Tanja Du?i?, Eleonora Carboni, Sylvain Bohic, Peter Cloetens, Paul Lingor
Mol Neurobiol 2015 Apr;
PMID: 25833099 [PubMed - as supplied by publisher]


The effect of tyrosine residues on ?-synuclein fibrillation.
Katja Pirc, Miha ?karabot, Lea Poga?nik, Eva ?erovnik, Nata?a Poklar-Ulrih
Acta Chim Slov 2015 ; 62(1):181-9
PMID: 25830974 [PubMed - as supplied by publisher]


A mobile cloud-based Parkinson's disease assessment system for home-based monitoring.
Di Pan, Rohit Dhall, Abraham Lieberman, Diana B Petitti
JMIR Mhealth Uhealth 2015 ; 3(1):e29
PMID: 25830687 [PubMed - as supplied by publisher]


Standardized extract of Withania somnifera (Ashwagandha) markedly offsets rotenone-induced locomotor deficits, oxidative impairments and neurotoxicity in Drosophila melanogaster.
M J Manjunath, Muralidhara
J Food Sci Technol 2015 Apr; 52(4):1971-81
PMID: 25829577 [PubMed - as supplied by publisher]


Autophagosome dynamics in neurodegeneration at a glance.
Yvette C Wong, Erika L F Holzbaur
J Cell Sci 2015 Apr; 128(7):1259-1267
PMID: 25829512 [PubMed - as supplied by publisher]


Decreased vesicular storage and aldehyde dehydrogenase activity in multiple system atrophy.
David S Goldstein, Patricia Sullivan, Courtney Holmes, Irwin J Kopin, Yehonatan Sharabi, Deborah C Mash
Parkinsonism Relat Disord 2015 Mar;
PMID: 25829070 [PubMed - as supplied by publisher]


Motion Sensors to Assess and Monitor Medical and Surgical Management of Parkinson's Disease.
Bryan Lieber, Blake Taylor, Geoff Appelboom, Guy McKhann, E Sander Connolly
World Neurosurg 2015 Mar;
PMID: 25827041 [PubMed - as supplied by publisher]


Mitochondrial Redox Dysfunction and Environmental Exposures.
Michael Aschner, Samuel W Caito
Antioxid Redox Signal 2015 Mar;
PMID: 25826672 [PubMed - as supplied by publisher]


Serum- glucocorticoid-inducible kinase 1 confers protection in cell-based and in in vivo neurotoxin models via the c-Jun N-terminal kinase signaling pathway.
Sarah Iqbal, Shannon Howard, Philip V LoGrasso
Mol Cell Biol 2015 Mar;
PMID: 25825522 [PubMed - as supplied by publisher]


Methyl-branched lipids promote the membrane adsorption of ?-synuclein by enhancing shallow lipid-packing defects.
Matthias Garten, Coline Prévost, Clotilde Cadart, Romain Gautier, Luc Bousset, Ronald Melki, Patricia Bassereau, Stefano Vanni
Phys Chem Chem Phys 2015 Mar;
PMID: 25824255 [PubMed - as supplied by publisher]


Herbicide paraquat induces sex-specific variation of neuroinflammation and neurodegeneration in Drosophila melanogaster.
Shauryabrota Dalui, Arindam Bhattacharyya
Indian J Biochem Biophys 2014 Dec; 51(6):567-73
PMID: 25823231 [PubMed - as supplied by publisher]


Transcriptomics of Maternal and Fetal Membranes Can Discriminate between Gestational-Age Matched Preterm Neonates with and without Cognitive Impairment Diagnosed at 18-24 Months.
Athina Pappas, Tinnakorn Chaiworapongsa, Roberto Romero, Steven J Korzeniewski, Josef C Cortez, Gaurav Bhatti, Nardhy Gomez-Lopez, Sonia S Hassan, Seetha Shankaran, Adi L Tarca
PLoS One 2015 ; 10(3):e0118573
PMID: 25822971 [PubMed - as supplied by publisher]


DJ-1 Knockout Augments Disease Severity and Shortens Survival in a Mouse Model of ALS.
Nirit Lev, Yael Barhum, Itay Lotan, Israel Steiner, Daniel Offen
PLoS One 2015 ; 10(3):e0117190
PMID: 25822630 [PubMed - as supplied by publisher]


Dual ?-agonist/?-antagonist opioid receptor modulation reduces levodopa-induced dyskinesia and corrects dysregulated striatal changes in the nonhuman primate model of Parkinson disease.
Lisa F Potts, Eun S Park, Jong-Min Woo, Bhagya L Dyavar Shetty, Arun Singh, Steven P Braithwaite, Michael Voronkov, Stella M Papa, M Maral Mouradian
Ann Neurol 2015 Mar;
PMID: 25820831 [PubMed - as supplied by publisher]


Gaucher-Associated Parkinsonism.
Yaqiong Li, Ping Li, Huimin Liang, Zhiquan Zhao, Makoto Hashimoto, Jianshe Wei
Cell Mol Neurobiol 2015 Mar;
PMID: 25820783 [PubMed - as supplied by publisher]


Syndromic parkinsonism and dementia associated with OPA1 missense mutations.
Valerio Carelli, Olimpia Musumeci, Leonardo Caporali, Claudia Zanna, Chiara La Morgia, Valentina Del Dotto, Anna Maria Porcelli, Michela Rugolo, Maria Lucia Valentino, Luisa Iommarini, Alessandra Maresca, Piero Barboni, Michele Carbonelli, Costantino Trombetta, Enza Maria Valente, Simone Patergnani, Carlotta Giorgi, Paolo Pinton, Giovanni Rizzo, Caterina Tonon, Raffaele Lodi, Patrizia Avoni, Rocco Liguori, Agostino Baruzzi, Antonio Toscano, Massimo Zeviani
Ann Neurol 2015 Mar;
PMID: 25820230 [PubMed - as supplied by publisher]


The diagnostic value of minor salivary gland biopsy in clinically diagnosed patients with Parkinson's disease: comparison with DAT PET scans.
Liyan Gao, Huimin Chen, Xin Li, Fangfei Li, Qiaohong Ou-Yang, Tao Feng
Neurol Sci 2015 Mar;
PMID: 25820147 [PubMed - as supplied by publisher]


Parkinson disease: ?-synuclein mutational screening and new clinical insight into the p.E46K mutation.
Márcia M G Pimentel, Fabíola C Rodrigues, Marco Antônio A Leite, Mário Campos Júnior, Ana Lucia Rosso, Denise H Nicaretta, João S Pereira, Delson José Silva, Marcus V Della Coletta, Luiz Felipe R Vasconcellos, Gabriella M Abreu, Jussara M Dos Santos, Cíntia B Santos-Rebouças
Parkinsonism Relat Disord 2015 Mar;
PMID: 25817515 [PubMed - as supplied by publisher]


A Peruvian family with a novel PARK2 mutation: Clinical and pathological characteristics.
Mario R Cornejo-Olivas, Luis Torres, Ignacio F Mata, Pilar Mazzetti, Diana Rivas, Carlos Cosentino, Miguel Inca-Martinez, Juan M Cuba, Cyrus P Zabetian, James B Leverenz
Parkinsonism Relat Disord 2015 Jan;
PMID: 25817512 [PubMed - as supplied by publisher]


Seeking a Mechanism for the Toxicity of Oligomeric ?-Synuclein.
Hazel L Roberts, David R Brown
Biomolecules 2015; 5(2):282-305
PMID: 25816357 [PubMed - as supplied by publisher]


Association of Parkinson's Disease and Its Subtypes with Agricultural Pesticide Exposures in Men: A Case-Control Study in France.
Frédéric Moisan, Johan Spinosi, Laurène Delabre, Véronique Gourlet, Jean-Louis Mazurie, Isabelle Bénatru, Marcel Goldberg, Marc G Weisskopf, Ellen Imbernon, Christophe Tzourio, Alexis Elbaz
Environ Health Perspect 2015 Mar;
PMID: 25815770 [PubMed - as supplied by publisher]


Mitochondrial dysfunction in Parkinson disease: evidence in mutant PARK2 fibroblasts.
Maria C Zanellati, Valentina Monti, Chiara Barzaghi, Chiara Reale, Nardo Nardocci, Alberto Albanese, Enza M Valente, Daniele Ghezzi, Barbara Garavaglia
Front Genet 2015 ; 6:78
PMID: 25815004 [PubMed - as supplied by publisher]


Midbrain catecholaminergic neurons co-express ?-synuclein and tau in progressive supranuclear palsy.
María Elena Erro Aguirre, María Victoria Zelaya, Javier Sánchez Ruiz de Gordoa, María Teresa Tuñón, José Luis Lanciego
Front Neuroanat 2015 ; 9:25
PMID: 25814937 [PubMed - as supplied by publisher]


Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins.
Ralf J Braun
Front Mol Neurosci 2015 ; 8:8
PMID: 25814926 [PubMed - as supplied by publisher]