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Kim and Libbe Erickson, R.N.

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Causes and Pathology

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Understanding Parkinson’s

Motor Symptoms


    Balance and Falls
    Gait or Freezing

    Nonmotor Symptoms and Complications



Sleep and Fatigue/ REM Behavior Sleep Disorder

    Gastrointestinal and Urinary Function

    Cognition and Hallucination

Impulse Control Disorder

Vision/Visual hallucination



Orthostatic Hypotension


Imaging Studies

Clinical Studies



Treating Parkinson’s

Current and potential medications/Therapies

    Surgical Treatments
Gene Therapy

Deep Brain Stimulation

Physical, Occupational and Speech Therapy



Art and Music

Complementary and Alternative Therapies

Living with a Parkinson’s Diagnosis



Care giving

Hospice/End of Life/Palliative Care

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Modulation of endoplasmic reticulum stress in Parkinson's disease.
Saori Tsujii, Mitsue Ishisaka, Hideaki Hara
Eur J Pharmacol 2015 Aug; 765:154-156
PMID: 26297973 [PubMed - as supplied by publisher]

Cholesterol facilitates interactions between ?-synuclein oligomers and charge-neutral membranes.
Andreas van Maarschalkerweerd, Valeria Vetri, Bente Vestergaard
FEBS Lett 2015 Aug;
PMID: 26297828 [PubMed - as supplied by publisher]

Synergistic effects of ceftriaxone and erythropoietin on neuronal and behavioral deficits in an MPTP-induced animal model of Parkinson's disease dementia.
Chiu-Ku Huang, Yen-Ting Chang, Tamara G Amstislavskaya, Maria A Tikhonova, Chih-Li Lin, Ching-Sui Hung, Te-Jen Lai, Ying-Jui Ho
Behav Brain Res 2015 Aug;
PMID: 26296668 [PubMed - as supplied by publisher]

Small molecule TrkB agonist deoxygedunin protects nigrostriatal dopaminergic neurons from 6-OHDA and MPTP induced neurotoxicity in rodents.
Shuke Nie, Yan Xu, Guiqin Chen, Kai Ma, Chao Han, Zhenli Guo, Zhentao Zhang, Keqiang Ye, Xuebing Cao
Neuropharmacology 2015 Aug; 99:448-458
PMID: 26282118 [PubMed - as supplied by publisher]

Suppression effects of O-demethyldemethoxycurcumin on thapsigargin triggered on endoplasmic reticulum stress in SK-N-SH cells.
Adchara Janyou, Chatchawan Changtam, Apichart Suksamrarn, Chainarong Tocharus, Jiraporn Tocharus
Neurotoxicology 2015 Aug; 50:92-100
PMID: 26264395 [PubMed - as supplied by publisher]

Contribution of brain serotonin subtype 1B receptors in levodopa-induced motor complications.
Nicolas Morin, Marc Morissette, Laurent Grégoire, Alex Rajput, Ali H Rajput, Thérèse Di Paolo
Neuropharmacology 2015 Aug; 99:356-368
PMID: 26254863 [PubMed - as supplied by publisher]

Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Ross B Mounsey, Sarah Mustafa, Lianne Robinson, Ruth A Ross, Gernot Riedel, Roger G Pertwee, Peter Teismann
Exp Neurol 2015 Aug; 273:36-44
PMID: 26244281 [PubMed - as supplied by publisher]

Environment-contact administration of rotenone: A new rodent model of Parkinson's disease.
Yan Liu, Jian-Dong Sun, Lian-Kun Song, Jing Li, Shi-Feng Chu, Yu-He Yuan, Nai-Hong Chen
Behav Brain Res 2015 Jul; 294:149-161
PMID: 26239001 [PubMed - as supplied by publisher]

Lovastatin induces neuroprotection by inhibiting inflammatory cytokines in 6-hydroxydopamine treated microglia cells.
Jun-Qiang Yan, Jia-Chun Sun, Ming-Ming Zhai, Li-Niu Cheng, Xiao-Li Bai, Cui-Ling Feng
Int J Clin Exp Med 2015 ; 8(6):9030-7
PMID: 26309556 [PubMed - as supplied by publisher]

How close are we to revealing the etiology of Parkinson's disease?
Kurt A Jellinger
Expert Rev Neurother 2015 Aug; :1-3
PMID: 26294223 [PubMed - as supplied by publisher]

Neuroprotection of Coenzyme Q10 in Neurodegenerative Diseases.
Xifei Yang, Yanling Zhang, Hua Xu, Xiaobin Luo, Jun Yu, Jianjun Liu, Raymond Chuen-Chung Chang
Curr Top Med Chem 2015 Aug;
PMID: 26311425 [PubMed - as supplied by publisher]

The Deleterious Effects of Oxidative and Nitrosative Stress on Palmitoylation, Membrane Lipid Rafts and Lipid-Based Cellular Signalling: New Drug Targets in Neuroimmune Disorders.
Gerwyn Morris, Ken Walder, Basant K Puri, Michael Berk, Michael Maes
Mol Neurobiol 2015 Aug;
PMID: 26310971 [PubMed - as supplied by publisher]

F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy.
Zhi Dong Zhou, Shao Ping Xie, Sushmitha Sathiyamoorthy, Wuan Ting Saw, Tan Ye Sing, Shin Hui Ng, Heidi Pek Hup Chua, Alyssa Mei Yan Tang, Fathima Shaffra, Zeng Li, Hongyan Wang, Patrick Ghim Hoe Ho, Mitchell Kim Peng Lai, Dario C Angeles, Tit Meng Lim, Eng King Tan
Hum Mol Genet 2015 Aug;
PMID: 26310625 [PubMed - as supplied by publisher]

?-Synuclein and nonhuman primate models of Parkinson's disease.
Scott C Vermilyea, Marina E Emborg
J Neurosci Methods 2015 Aug; 255:38-51
PMID: 26247888 [PubMed - as supplied by publisher]

Ion mobility-mass spectrometry-based screening for inhibition of ?- synuclein aggregation.
Yanqin Liu, Michael Graetz, Lam Ho, Tara L Pukala
Eur J Mass Spectrom (Chichester, Eng) 2015 ; 21(3):255-64
PMID: 26307705 [PubMed - as supplied by publisher]

Rapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathy.
Xiang Bai, Margaret Chia-Ying Wey, Elizabeth Fernandez, Matthew J Hart, Jonathan Gelfond, Alex F Bokov, Sheela Rani, Randy Strong
Pathobiol Aging Age Relat Dis 2015 ; 5:28743
PMID: 26306821 [PubMed - as supplied by publisher]

Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation.
Aoife P Kiely, Helen Ling, Yasmine T Asi, Eleanna Kara, Christos Proukakis, Anthony H Schapira, Huw R Morris, Helen C Roberts, Steven Lubbe, Patricia Limousin, Patrick A Lewis, Andrew J Lees, Niall Quinn, John Hardy, Seth Love, Tamas Revesz, Henry Houlden, Janice L Holton
Mol Neurodegener 2015 ; 10(1):41
PMID: 26306801 [PubMed - as supplied by publisher]

Hsp31 is a Stress-Response Chaperone that Intervenes in the Protein Misfolding Process.
Chia-Jui Tsai, Kiran Aslam, Holli M Drendel, Josephat M Asiago, Kourtney M Goode, Lake N Paul, Jean-Christophe Rochet, Tony R Hazbun
J Biol Chem 2015 Aug;
PMID: 26306045 [PubMed - as supplied by publisher]

Compensatory postural adjustments in Parkinson's disease assessed via a virtual reality environment.
Darya Yelshyna, Miguel F Gago, Estela Bicho, Vítor Fernandes, Nuno F Gago, Luís Costa, Hélder Silva, Maria Lurdes Rodrigues, Luís Rocha, Nuno Sousa
Behav Brain Res 2015 Aug;
PMID: 26304718 [PubMed - as supplied by publisher]

The 6-hydroxydopamine model and parkinsonian pathophysiology: Novel findings in an older model.
D Hernandez-Baltazar, L M Zavala-Flores, A Villanueva-Olivo
Neurologia 2015 Aug;
PMID: 26304655 [PubMed - as supplied by publisher]

Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease.
WeiZhen Liu, Yanwei Li, Jaishree Jalewa, Taylor Saunders-Wood, Lin Li, Christian Hölscher
Eur J Pharmacol 2015 Aug;
PMID: 26302060 [PubMed - as supplied by publisher]

Epicatechin Reduces Striatal MPP(+)-Induced Damage in Rats through Slight Increases in SOD-Cu,Zn Activity.
M Rubio-Osornio, E Gorostieta-Salas, S Montes, F Pérez-Severiano, C Rubio, C Gómez, C Ríos, J Guevara
Oxid Med Cell Longev 2015 ; 2015:276039
PMID: 26301040 [PubMed - as supplied by publisher]

The neurotoxin 1-methyl-4-phenylpyridinium (MPP(+)) alters hippocampal excitatory synaptic transmission by modulation of the GABAergic system.
YuYing Huang, JunFang Chen, Ying Chen, YingHan Zhuang, Mu Sun, Thomas Behnisch
Front Cell Neurosci 2015 ; 9:299
PMID: 26300734 [PubMed - as supplied by publisher]

Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.
Chrystian J Alves, Rafael Dariolli, Frederico M Jorge, Matheus R Monteiro, Jessica R Maximino, Roberto S Martins, Bryan E Strauss, José E Krieger, Dagoberto Callegaro, Gerson Chadi
Front Cell Neurosci 2015 ; 9:289
PMID: 26300727 [PubMed - as supplied by publisher]

Protective effects of Ndfip1 on MPP(+)-induced apoptosis in MES23.5 cells and its underlying mechanisms.
Kai Liu, Huamin Xu, Hengwei Xiang, Peng Sun, Junxia Xie
Exp Neurol 2015 Aug;
PMID: 26300475 [PubMed - as supplied by publisher]

Alpha-linolenic acid suppresses dopaminergic neurodegeneration induced by 6-OHDA in C. elegans.
S Shashikumar, H Pradeep, Salim Chinnu, P S Rajini, G K Rajanikant
Physiol Behav 2015 Aug;
PMID: 26300470 [PubMed - as supplied by publisher]

Human Hsp70 Disaggregase Reverses Parkinson's-Linked ?-Synuclein Amyloid Fibrils.
Xuechao Gao, Marta Carroni, Carmen Nussbaum-Krammer, Axel Mogk, Nadinath B Nillegoda, Anna Szlachcic, D Lys Guilbride, Helen R Saibil, Matthias P Mayer, Bernd Bukau
Mol Cell 2015 Aug;
PMID: 26300264 [PubMed - as supplied by publisher]

Trehalose intake induces chaperone molecules along with autophagy in a mouse model of Lewy body disease.
Kunikazu Tanji, Yasuo Miki, Atsushi Maruyama, Junsei Mimura, Tomoh Matsumiya, Fumiaki Mori, Tadaatsu Imaizumi, Ken Itoh, Koichi Wakabayashi
Biochem Biophys Res Commun 2015 Aug;
PMID: 26299928 [PubMed - as supplied by publisher]

New insights into cellular ?-synuclein homeostasis in health and disease.
Ulf Dettmer, Dennis Selkoe, Tim Bartels
Curr Opin Neurobiol 2015 Aug; 36:15-22
PMID: 26282834 [PubMed - as supplied by publisher]

Tricyclic Antidepressants Amitriptyline and Desipramine Induced Neurotoxicity Associated with Parkinson's Disease.
Min-Yeong Lee, Seokheon Hong, Nahmhee Kim, Ki Soon Shin, Shin Jung Kang
Mol Cells 2015 Aug; 38(8):734-40
PMID: 26242194 [PubMed - as supplied by publisher]

Chronic restraint stress triggers the dopaminergic and noradrenergic neurodegeneration: Possible role of chronic stress for the onset of Parkinson's disease.
Shuei Sugama, Kazunari Sekiyama, Tohru Kodama, Yoshiki Takamatsu, Takato Takenouchi, Makoto Hashimoto, Conti Bruno, Yoshihiko Kakinuma
Brain Behav Immun 2015 Aug;
PMID: 26291405 [PubMed - as supplied by publisher]

Edaravone leads to proteome changes indicative of neuronal cell protection in response to oxidative stress.
Mohammad-Saeid Jami, Zahra Salehi-Najafabadi, Fereshteh Ahmadinejad, Esthelle Hoedt, Morteza Hashemzadeh Chaleshtori, Mahdi Ghatrehsamani, Thomas A Neubert, Jan Petter Larsen, Simon Geir Møller
Neurochem Int 2015 Jul;
PMID: 26232623 [PubMed - as supplied by publisher]

PAX6 expression may be protective against dopaminergic cell loss in Parkinson's disease.
M G Thomas, C Welch, L Stone, P Allan, R A Barker, R B White
CNS Neurol Disord Drug Targets 2015 Aug;
PMID: 26295830 [PubMed - as supplied by publisher]

The association of palmitoylethanolamide with luteolin decreases neuroinflammation and stimulates autophagy in Parkinson's disease model.
Rosalba Siracusa, Irene Paterniti, Daniela Impellizzeri, Marika Cordaro, Rosalia Crupi, Michele Navarra, Salvatore Cuzzocrea, Emanuela Esposito
CNS Neurol Disord Drug Targets 2015 Aug;
PMID: 26295827 [PubMed - as supplied by publisher]

A Fluorescence Resonance Energy Transfer Assay For Monitoring ?-Synclein Aggregation In A Caenorhabditis elegans Model For Parkinson's Disease.
Archana Nagarajan, Rakesh Bodhicharla, Jody Winter, Charumathi Anbalagan, Kevin Morgan, Mark Searle, Aamir Nazir, Ademola Adenle, April Fineberg, Declan Brady, Kelly Vere, Jo Richens, Paul O'Shea, David Bell, David de-Pomerai
CNS Neurol Disord Drug Targets 2015 Aug;
PMID: 26295817 [PubMed - as supplied by publisher]

Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration.
Jeffrey R Liddell
Neurodegener Dis Manag 2015 Aug;
PMID: 26295717 [PubMed - as supplied by publisher]

Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain.
Joanne Clark-Matott, Ayesha Saleem, Ying Dai, Yevgeniya Shurubor, Xiaoxing Ma, Adeel Safdar, Myron Flint Beal, Mark Tarnopolsky, David K Simon
Neurobiol Aging 2015 Jul;
PMID: 26294258 [PubMed - as supplied by publisher]

New treatments for levodopa-induced motor complications.
Olivier Rascol, Santiago Perez-Lloret, Joaquim J Ferreira
Mov Disord 2015 Aug;
PMID: 26293004 [PubMed - as supplied by publisher]

Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/?-synuclein aggregation.
Ling-Yan Su, Hao Li, Li Lv, Yue-Mei Feng, Guo-Dong Li, Rongcan Luo, He-Jiang Zhou, Xiao-Guang Lei, Liang Ma, Jia-Li Li, Lin Xu, Xin-Tian Hu, Yong-Gang Yao
Autophagy 2015 Aug; :0
PMID: 26292069 [PubMed - as supplied by publisher]

Lymphocytes reduce nigrostriatal deficits in the 6-hydroxydopamine mouse model of Parkinson's disease.
Chi Wang Ip, Sandra K Beck, Jens Volkmann
J Neural Transm 2015 Aug;
PMID: 26290125 [PubMed - as supplied by publisher]

Psychosocial difficulties from the perspective of persons with neuropsychiatric disorders.
Michaela Coenen, Maria Cabello, Silvia Umlauf, José Luis Ayuso-Mateos, Marta Anczewska, Jouni Tourunen, Matilde Leonardi, Alarcos Cieza,
Disabil Rehabil 2015 Aug; :1-12
PMID: 26289372 [PubMed - as supplied by publisher]

Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment.
Brittany N Dugger, Kathryn Davis, Michael Malek-Ahmadi, Joseph G Hentz, Shawn Sandhu, Thomas G Beach, Charles H Adler, Richard J Caselli, Travis A Johnson, Geidy E Serrano, Holly A Shill, Christine Belden, Erika Driver-Dunckley, John N Caviness, Lucia I Sue, Sandra Jacobson, Jessica Powell, Marwan N Sabbagh
BMC Neurol 2015 ; 15:146
PMID: 26289075 [PubMed - as supplied by publisher]

Neuroprotective potential of Beta vulgaris L. in Parkinson's disease.
Vandana S Nade, Laxman A Kawale, Shankar S Zambre, Amit B Kapure
Indian J Pharmacol 2015 Jul-Aug; 47(4):403-8
PMID: 26288473 [PubMed - as supplied by publisher]

Gefitinib and Erlotinib Lead to Phosphorylation of Eukaryotic Initiation Factor 2 Alpha Independent of Epidermal Growth Factor Receptor in A549 Cells.
Satoshi Koyama, Tomohiro Omura, Atsushi Yonezawa, Satoshi Imai, Shunsaku Nakagawa, Takayuki Nakagawa, Ikuko Yano, Kazuo Matsubara
PLoS One 2015 ; 10(8):e0136176
PMID: 26288223 [PubMed - as supplied by publisher]

Toxic Oligomeric Alpha-Synuclein Variants Present in Human Parkinson's Disease Brains Are Differentially Generated in Mammalian Cell Models.
Wei Xin, Sharareh Emadi, Stephanie Williams, Qiang Liu, Philip Schulz, Ping He, Now Bahar Alam, Jie Wu, Michael R Sierks
Biomolecules 2015 ; 5(3):1634-51
PMID: 26287258 [PubMed - as supplied by publisher]

Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?
Jaime M Ross, Lars Olson, Giuseppe Coppotelli
Int J Mol Sci 2015 ; 16(8):19458-76
PMID: 26287188 [PubMed - as supplied by publisher]

Propagation of prions causing synucleinopathies in cultured cells.
Amanda L Woerman, Jan Stöhr, Atsushi Aoyagi, Ryan Rampersaud, Zuzana Krejciova, Joel C Watts, Takao Ohyama, Smita Patel, Kartika Widjaja, Abby Oehler, David W Sanders, Marc I Diamond, William W Seeley, Lefkos T Middleton, Steve M Gentleman, Daniel A Mordes, Thomas C Südhof, Kurt Giles, Stanley B Prusiner
Proc Natl Acad Sci U S A 2015 Aug;
PMID: 26286986 [PubMed - as supplied by publisher]

VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin.
Bilal R Malik, Vinay K Godena, Alexander J Whitworth
Hum Mol Genet 2015 Aug;
PMID: 26251041 [PubMed - as supplied by publisher]

DJ1 expression downregulates in neuroblastoma cells (SK-N-MC) chronically exposed to HIV-1 and cocaine.
Upal Roy, Venkata S R Atluri, Marisela Agudelo, Adriana Yndart, Zaohua Huang, Madhavan Nair
Front Microbiol 2015 ; 6:749
PMID: 26284039 [PubMed - as supplied by publisher]

Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release.
Mattia Volta, Stefano Cataldi, Dayne Beccano-Kelly, Lise Munsie, Igor Tatarnikov, Patrick Chou, Sabrina Bergeron, Emma Mitchell, Roscoe Lim, Jaskaran Khinda, Alejandro Lloret, C Frank Bennett, Carmela Paradiso, Michele Morari, Matthew J Farrer, Austen J Milnerwood
Parkinsonism Relat Disord 2015 Aug;
PMID: 26282470 [PubMed - as supplied by publisher]

Zingerone activates VMAT2 during MPP(+) -induced Cell Death.
Jae-Sun Choi, Woom-Yee Bae, Chan Park, Joo-Won Jeong
Phytother Res 2015 Aug;
PMID: 26282055 [PubMed - as supplied by publisher]

Nrf2-a therapeutic target for the treatment of neurodegenerative diseases.
Delinda A Johnson, Jeffrey A Johnson
Free Radic Biol Med 2015 Aug; :FRBMD1500535
PMID: 26281945 [PubMed - as supplied by publisher]

Contrasts Between Patients With Lewy Body Dementia Syndromes and APOE-?3/?3 Patients With Late-onset Alzheimer Disease Dementia.
Fabricio F Oliveira, Fernando C Machado, Gustavo Sampaio, Sheilla M C Marin, Elizabeth S Chen, Marilia C Smith, Paulo H F Bertolucci
Neurologist 2015 Aug; 20(2):35-41
PMID: 26280289 [PubMed - as supplied by publisher]

Expression of synaptophysin protein in different dopaminergic cell lines.
Xiang Bai, Randy Strong
J Biochem Pharmacol Res 2014 Dec; 2(4):185-190
PMID: 26279968 [PubMed - as supplied by publisher]

Cholesterol - A putative endogenous contributor towards Parkinson's disease.
Rajib Paul, Amarendranath Choudhury, Anupom Borah
Neurochem Int 2015 Jul;
PMID: 26232622 [PubMed - as supplied by publisher]

Re-exploring the N-phenylpicolinamide derivatives to develop mGlu4 ligands with improved affinity and in vitro microsomal stability.
Zhaoda Zhang, Kun-Eek Kil, Pekka Poutiainen, Ji-Kyung Choi, Hye-Jin Kang, Xi-Ping Huang, Bryan L Roth, Anna-Liisa Brownell
Bioorg Med Chem Lett 2015 Sep; 25(18):3956-60
PMID: 26231155 [PubMed - as supplied by publisher]

Pyrroloquinoline quinone-conferred neuroprotection in rotenone models of Parkinson's disease.
Jiaojiao Qin, Meilong Wu, Xiaorong Gao, Jingjing Zhang, Xingyue Dong, Jinyan Ji, Yuxi Zhang, Lin Zhou, Qi Zhang, Fei Ding
Toxicol Lett 2015 Aug;
PMID: 26276080 [PubMed - as supplied by publisher]

Dopaminergic Toxin 1-Methyl-4-Phenylpyridinium, Proteins ?-Synuclein and Glia Maturation Factor Activate Mast Cells and Release Inflammatory Mediators.
Duraisamy Kempuraj, Ramasamy Thangavel, Evert Yang, Sagar Pattani, Smita Zaheer, Donna A Santillan, Mark K Santillan, Asgar Zaheer
PLoS One 2015 ; 10(8):e0135776
PMID: 26275153 [PubMed - as supplied by publisher]

Selective Depletion of Microglia from Cerebellar Granule Cell Cultures Using L-leucine Methyl Ester.
Joseph Jebelli, Thomas Piers, Jennifer Pocock
J Vis Exp 2015 ; (101)
PMID: 26275019 [PubMed - as supplied by publisher]

Amyloid Fibrils Are the Molecular Trigger of Inflammation in Parkinson's Disease.
Adelin Gustot, José Ignacio Gallea, Rabia Sarroukh, M Soledad Celej, Jean-Marie Ruysschaert, Vincent Raussens
Biochem J 2015 Aug;
PMID: 26272943 [PubMed - as supplied by publisher]

P-glycoprotein Transport of Neurotoxic Pesticides.
Sarah E Lacher, Kasse Skagen, Joachim Veit, Rachel Dalton, Erica L Woodahl
J Pharmacol Exp Ther 2015 Aug;
PMID: 26272936 [PubMed - as supplied by publisher]

Tea and Parkinson's disease: Constituents of tea synergize with antiparkinsonian drugs to provide better therapeutic benefits.
Debashis Dutta, Kochupurackal P Mohanakumar
Neurochem Int 2015 Aug;
PMID: 26271432 [PubMed - as supplied by publisher]

The Inflammatory Marker YKL-40 Is Elevated in Cerebrospinal Fluid from Patients with Alzheimer's but Not Parkinson's Disease or Dementia with Lewy Bodies.
Malin Wennström, Yulia Surova, Sara Hall, Christer Nilsson, Lennart Minthon, Oskar Hansson, Henrietta M Nielsen
PLoS One 2015 ; 10(8):e0135458
PMID: 26270969 [PubMed - as supplied by publisher]

Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of ?-Synuclein Oligomers.
Mathew H Horrocks, Laura Tosatto, Alexander J Dear, Gonzalo A Garcia, Marija Iljina, Nunilo Cremades, Mauro Dalla Serra, Tuomas P J Knowles, Christopher M Dobson, David Klenerman
Anal Chem 2015 Aug;
PMID: 26258431 [PubMed - as supplied by publisher]

Alpha-Synuclein Fibrils Interact with Dopamine Reducing its Cytotoxicity on PC12 Cells.
Masoome Khalife, Dina Morshedi, Farhang Aliakbari, Amir Tayaranian Marvian, Hossein Mohammad Beigi, Sadegh Azimzadeh Jamalkandi, Francisco Pan-Montojo
Protein J 2015 Aug; 34(4):291-303
PMID: 26250981 [PubMed - as supplied by publisher]

Resting state in Parkinson's disease dementia and dementia with Lewy bodies: commonalities and differences.
Luis R Peraza, Sean J Colloby, Michael J Firbank, G Shirmin Greasy, Ian G McKeith, Marcus Kaiser, John O'Brien, John-Paul Taylor
Int J Geriatr Psychiatry 2015 Aug;
PMID: 26270627 [PubMed - as supplied by publisher]

The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus.
Eric S Sweet, Bernadette Saunier-Rebori, Zhenyu Yue, Robert D Blitzer
J Neurosci 2015 Aug; 35(32):11190-5
PMID: 26269629 [PubMed - as supplied by publisher]

Gene expression profiling predicts pathways and genes associated with Parkinson's disease.
Shuang Liu, Yong Zhang, Hong Bian, Xiaohong Li
Neurol Sci 2015 Aug;
PMID: 26269422 [PubMed - as supplied by publisher]

Expanding the ubiquitin code through post-translational modification.
Lina Herhaus, Ivan Dikic
EMBO Rep 2015 Aug;
PMID: 26268526 [PubMed - as supplied by publisher]

NADPH oxidase mediated maneb- and paraquat-induced oxidative stress in rat polymorphs: Crosstalk with mitochondrial dysfunction.
Smriti Shukla, Deepali Singh, Vinod Kumar, Amit Kumar Chauhan, Shweta Singh, Israr Ahmad, Haushila Prasad Pandey, Chetna Singh
Pestic Biochem Physiol 2015 Sep; 123:74-86
PMID: 26267055 [PubMed - as supplied by publisher]

Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models.
Mehdi Djelloul, Staffan Holmqvist, Antonio Boza-Serrano, Carla Azevedo, Maggie S Yeung, Stefano Goldwurm, Jonas Frisén, Tomas Deierborg, Laurent Roybon
Stem Cell Reports 2015 Aug; 5(2):174-84
PMID: 26235891 [PubMed - as supplied by publisher]

Protective effect of vagotomy suggests source organ for Parkinson's disease.
Madison T Gray, David G Munoz, Michael G Schlossmacher, Douglas A Gray, John M Woulfe
Ann Neurol 2015 Aug;
PMID: 26267415 [PubMed - as supplied by publisher]

Nanoparticles, Neurotoxicity and Neurodegenerative Diseases.
Gohar Mushtaq, Jalaluddin A Khan, Ebenezer Joseph, Mohammad A Kamal
Curr Drug Metab 2015 Aug;
PMID: 26264205 [PubMed - as supplied by publisher]

Myeloid cell leukemia 1 (Mcl(-1)) protects against 1-methyl-4-phenylpyridinium ion (MPP+) induced apoptosis in Parkinson's disease.
Lijing Fan, Li Jiang, Zhongde Du
Metab Brain Dis 2015 Aug;
PMID: 26264181 [PubMed - as supplied by publisher]

Does the cerebrospinal fluid reflect altered redox state but not neurotrophic support loss in Parkinson's disease?
Angel Martin de Pablos, Jose-Manuel Garcia-Moreno, Emilio Fernandez
Antioxid Redox Signal 2015 Aug;
PMID: 26263410 [PubMed - as supplied by publisher]

p38 MAPK and PI3K/AKT Signalling Cascades inParkinson's Disease.
Saurabh Kumar Jha, Niraj Kumar Jha, Rohan Kar, Rashmi K Ambasta, Pravir Kumar
Int J Mol Cell Med 2015 ; 4(2):67-86
PMID: 26261796 [PubMed - as supplied by publisher]

Active immunization therapies.
Achim Schneeberger, Lanay Tierney, Markus Mandler
Mov Disord 2015 Aug;
PMID: 26260853 [PubMed - as supplied by publisher]

Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation.
Koji Yamano, Bruno B Queliconi, Fumika Koyano, Yasushi Saeki, Takatsugu Hirokawa, Keiji Tanaka, Noriyuki Matsuda
J Biol Chem 2015 Aug;
PMID: 26260794 [PubMed - as supplied by publisher]

Region-Specific Alterations of Matrix Metalloproteinase Activity in Multiple System Atrophy.
Fares Bassil, Arnaud Monvoisin, Marie-Helene Canron, Anne Vital, Wassilios G Meissner, François Tison, Pierre-Olivier Fernagut
Mov Disord 2015 Aug;
PMID: 26260627 [PubMed - as supplied by publisher]

Neuroinflammatory processes in cognitive disorders: Is there a role for flavonoids and n-3 polyunsaturated fatty acids in counteracting their detrimental effects?
David Vauzour, Anneloes Martinsen, Sophie Layé
Neurochem Int 2015 Aug;
PMID: 26260547 [PubMed - as supplied by publisher]

Alteration of upstream autophagy-related proteins (ULK1, ULK2, Beclin1, VPS34, and AMBRA1) in Lewy body disease.
Yasuo Miki, Kunikazu Tanji, Fumiaki Mori, Jun Utsumi, Hidenao Sasaki, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi
Brain Pathol 2015 Aug;
PMID: 26260450 [PubMed - as supplied by publisher]

Genetic Variants in GAPDH Confer Susceptibility to Sporadic Parkinson's Disease in a Chinese Han Population.
Ling Liu, Nian Xiong, Ping Zhang, Chunnuan Chen, Jinsha Huang, Guoxin Zhang, Xiaoyun Xu, Yan Shen, Zhicheng Lin, Tao Wang
PLoS One 2015 ; 10(8):e0135425
PMID: 26258539 [PubMed - as supplied by publisher]

Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson Disease.
David C Bäckström, Magdalena Eriksson Domellöf, Jan Linder, Bob Olsson, Annika Öhrfelt, Miles Trupp, Henrik Zetterberg, Kaj Blennow, Lars Forsgren
JAMA Neurol 2015 Aug;
PMID: 26258692 [PubMed - as supplied by publisher]

DNA damage in neurodegenerative diseases.
Fabio Coppedè, Lucia Migliore
Mutat Res 2015 Jun; 776:84-97
PMID: 26255941 [PubMed - as supplied by publisher]

A Ubl/ubiquitin switch in the activation of Parkin.
Véronique Sauvé, Asparouh Lilov, Marjan Seirafi, Marta Vranas, Shafqat Rasool, Guennadi Kozlov, Tara Sprules, Jimin Wang, Jean-François Trempe, Kalle Gehring
EMBO J 2015 Aug;
PMID: 26254305 [PubMed - as supplied by publisher]

NEURODEGENERATION. Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A?, tau, and ?-synuclein.
Michel Goedert
Science 2015 Aug; 349(6248):1255555
PMID: 26250687 [PubMed - as supplied by publisher]

Effects of transcranial direct current stimulation upon attention and visuoperceptual function in Lewy body dementia: a preliminary study.
Greg J Elder, Michael J Firbank, Hrishikesh Kumar, Payel Chatterjee, Titas Chakraborty, Alakananda Dutt, John-Paul Taylor
Int Psychogeriatr 2015 Aug; :1-7
PMID: 26250473 [PubMed - as supplied by publisher]

Therapeutic potentials of human adipose-derived stem cells on the mouse model of Parkinson's disease.
Hee Soon Choi, Hee Jin Kim, Jin-Hwan Oh, Hyeong-Geun Park, Jeong Chan Ra, Keun-A Chang, Yoo-Hun Suh
Neurobiol Aging 2015 Jun;
PMID: 26242706 [PubMed - as supplied by publisher]

Using iPS Cells toward the Understanding of Parkinson's Disease.
Roger Torrent, Francesca De Angelis Rigotti, Patrizia Dell'Era, Maurizio Memo, Angel Raya, Antonella Consiglio
J Clin Med 2015 ; 4(4):548-66
PMID: 26239346 [PubMed - as supplied by publisher]

Proton MR Spectroscopy for Diagnosis and Evaluation of Treatment Efficacy in Parkinson Disease.
Leslie Mazuel, Carine Chassain, Betty Jean, Bruno Pereira, Aurélie Cladière, Claudine Speziale, Franck Durif
Radiology 2015 Aug; :142764
PMID: 26237591 [PubMed - as supplied by publisher]

Protective effects of ginseng on neurological disorders.
Wei-Yi Ong, Tahira Farooqui, Hwee-Ling Koh, Akhlaq A Farooqui, Eng-Ang Ling
Front Aging Neurosci 2015 ; 7:129
PMID: 26236231 [PubMed - as supplied by publisher]

Clinicopathological characteristics of freezing of gait in autopsy-confirmed Parkinson's disease.
Tuhin Virmani, Carol B Moskowitz, Jean-Paul Vonsattel, Stanley Fahn
Mov Disord 2015 Aug;
PMID: 26234730 [PubMed - as supplied by publisher]

Evidence for early and progressive ultrasonic vocalization and oromotor deficits in a PINK1 gene knockout rat model of Parkinson's disease.
Laura M Grant, Cynthia A Kelm-Nelson, Breanna L Hilby, Katherine V Blue, Eunice S Paul Rajamanickam, Joshua D Pultorak, Shelia M Fleming, Michelle R Ciucci
J Neurosci Res 2015 Jul;
PMID: 26234713 [PubMed - as supplied by publisher]

Memantine and reduced time with dyskinesia in Parkinson's Disease.
K Wictorin, H Widner
Acta Neurol Scand 2015 Aug;
PMID: 26234336 [PubMed - as supplied by publisher]

A Novel Compound ITC-3 Activates the Nrf2 Signaling and Provides Neuroprotection in Parkinson's Disease Models.
Ji Ae Lee, Hyo Jin Son, Ki Duk Park, Se Hee Han, Nari Shin, Ji Hyun Kim, Hye Ri Kim, Dong Jin Kim, Onyou Hwang
Neurotox Res 2015 Aug;
PMID: 26233727 [PubMed - as supplied by publisher]

Ethanol extract of Bupleurum falcatum Linne and saikosaponins inhibit neuroinflammation via inhibition of NF-?B.
Wook Ha Park, Sora Kang, Ying Piao, Christine Jeehye Pak, Myung Sook Oh, Jinwoong Kim, Min Seo Kang, Youngmi Kim Pak
J Ethnopharmacol 2015 Jul;
PMID: 26231448 [PubMed - as supplied by publisher]

A Prospective Open-Label Study of Combined Treatment for Idiopathic Parkinson's Disease Using Acupuncture and Bee Venom Acupuncture as an Adjunctive Treatment.
Kyeong-Hee Doo, Ji-Hyun Lee, Seung-Yeon Cho, Woo-Sang Jung, Sang-Kwan Moon, Jung-Mi Park, Chang-Nam Ko, Ho Kim, Hi-Joon Park, Seong-Uk Park
J Altern Complement Med 2015 Jul;
PMID: 26230989 [PubMed - as supplied by publisher]

A randomized, double-blind phase I/IIa study of intranasal glutathione in Parkinson's disease.
Laurie K Mischley, James B Leverenz, Richard C Lau, Nayak L Polissar, Moni B Neradilek, Ali Samii, Leanna J Standish
Mov Disord 2015 Jul;
PMID: 26230671 [PubMed - as supplied by publisher]

18F-FDG PET is an early predictor of overall survival in suspected atypical parkinsonism.
Sabine Hellwig, Lars Frings, Florian Amtage, Ralph Buchert, Timo S Spehl, Michel Rijntjes, Oliver Tüscher, Cornelius Weiller, Wolfgang Andreas Weber, Werner Vach, Philipp T Meyer
J Nucl Med 2015 Jul;
PMID: 26229141 [PubMed - as supplied by publisher]