Causes and Pathology

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Stress, Allostatic Load, Catecholamines, and Other Neurotransmitters in Neurodegenerative Diseases.
David S Goldstein
Cell Mol Neurobiol 2012 Feb;
PMID: Object id #2122297542 [PubMed - as supplied by publisher]

CHO cells expressing the human P(5)-ATPase ATP13A2 are more sensitive to the toxic effects of herbicide Paraquat.
Felicitas de Tezanos Pinto, Gerardo Raul Corradi, Diego Pablo de la Hera, Hugo Pedro Adamo
Neurochem Int 2012 Jan; 60(3):243-248
PMID: Object id #120422265822 [PubMed - as supplied by publisher]

Matrix metalloproteinase-3 is activated by HtrA2/Omi in dopaminergic cells: Relevance to Parkinson's disease.
Eun Jung Shin, Eun-Mee Kim, Ji Ae Lee, Hyangshuk Rhim, Onyou Hwang
Neurochem Int 2012 Jan; 60(3):249-256
PMID: Object id #120122265821 [PubMed - as supplied by publisher]

Effects of MK-801 on recognition and neurodegeneration in an MPTP-induced Parkinson's rat model.
Ming-Hong Hsieh, Siao-Lin Gu, Shih-Chun Ho, Cornelius Rainer Pawlak, Chih-Li Lin, Ying-Jui Ho, Te-Jen Lai, Fu-Ying Wu
Behav Brain Res 2012 Jan; 229(1):41-47
PMID: Object id #244522227506 [PubMed - as supplied by publisher]

Dementia with lewy bodies: diagnosis and management for primary care providers.
Melanie Zupancic, Aman Mahajan, Kamna Handa
Prim Care Companion CNS Disord 2011 ; 13(5)
PMID: Object id #3422295275 [PubMed - as supplied by publisher]

A comparison between colonic submucosa and mucosa to detect Lewy pathology in Parkinson's disease.
H Pouclet, T Lebouvier, E Coron, S B Des Varannes, M Neunlist, P Derkinderen
Neurogastroenterol Motil 2012 Jan;
PMID: Object id #5422292943 [PubMed - as supplied by publisher]

Monitoring Oxidative Stress Biomarkers in the Lipidome: Is There A Roadmap For "Human Inspection"?
Harald Jungnickel, Jutta Tentschert, Andreas Luch
Curr Mol Med 2012 Jan;
PMID: Object id #9022292439 [PubMed - as supplied by publisher]

Paraquat, but Not Maneb, Induces Synucleinopathy and Tauopathy in Striata of Mice through Inhibition of Proteasomal and Autophagic Pathways.
Jonathan Wills, Joel Credle, Adam W Oaks, Valeriy Duka, Jae-Hoon Lee, Jessica Jones, Anita Sidhu
PLoS One 2012 ; 7(1):e30745
PMID: Object id #11622292029 [PubMed - as supplied by publisher]

Genetic Dissection of Strain Dependent Paraquat-induced Neurodegeneration in the Substantia Nigra Pars Compacta.
Yun Jiao, Lu Lu, Robert W Williams, Richard J Smeyne
PLoS One 2012 ; 7(1):e29447
PMID: Object id #13422291891 [PubMed - as supplied by publisher]

An evaluation of the impact of MAPT, SNCA and APOE on the burden of Alzheimer's and Lewy body pathology.
Christian Wider, Owen A Ross, Kenya Nishioka, Michael G Heckman, Carles Vilariño-Güell, Barbara Jasinska-Myga, Nilufer Erketin-Taner, Rosa Rademakers, Neill R Graff-Radford, Deborah C Mash, Spiridon Papapetropoulos, Ranjan Duara, Hirotake Uchikado, Zbigniew K Wszolek, Matthew J Farrer, Dennis W Dickson
J Neurol Neurosurg Psychiatry 2012 Jan;
PMID: Object id #15922291217 [PubMed - as supplied by publisher]

Mechanisms to prevent caspase activation in rotenone-induced dopaminergic neurodegeneration: role of ATP depletion and procaspase-9 degradation.
Heewon Kang, Baek-Soo Han, Su-Jeong Kim, Young J Oh
Apoptosis 2012 Feb;
PMID: Object id #19922289916 [PubMed - as supplied by publisher]

Gaucher disease and the synucleinopathies: refining the relationship.
Tessa N Campbell, Francis Ym Choy
Orphanet J Rare Dis 2012 Jan; 7(1):12
PMID: Object id #22722289779 [PubMed - as supplied by publisher]

Brain-derived neurotrophic factor-mediated effects on mitochondrial respiratory coupling and neuroprotection share the same molecular signalling pathways.
Anthony Markham, Ian Cameron, Rasneer Bains, Paul Franklin, Janos P Kiss, Leslie Schwendimann, Pierre Gressens, Michael Spedding
Eur J Neurosci 2012 Feb; 35(3):366-374
PMID: Object id #25422288477 [PubMed - as supplied by publisher]

Drosophila Models of Proteinopathies: the Little Fly that Coulds.
Diego E Rincon-Limas, Kurt Jensen, Pedro Fernandez-Funez
Curr Pharm Des 2012 Jan;
PMID: Object id #27622288402 [PubMed - as supplied by publisher]

Parkinson disease: The gut as a route of entry for ?-synuclein in PD.
Nat Rev Neurol 2012 Jan;
PMID: Object id #100822270024 [PubMed - as supplied by publisher]

Inter-hemispheric asymmetry of nigrostriatal dopaminergic lesion: a possible compensatory mechanism in Parkinson's disease.
Javier Blesa, Carlos Juri, Miguel Á García-Cabezas, Rebeca Adánez, Miguel Á Sánchez-González, Carmen Cavada, José A Obeso
Front Syst Neurosci 2011 ; 5:92
PMID: Object id #30222287944 [PubMed - as supplied by publisher]

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.
Peng Lei, Scott Ayton, David I Finkelstein, Loredana Spoerri, Giuseppe D Ciccotosto, David K Wright, Bruce X W Wong, Paul A Adlard, Robert A Cherny, Linh Q Lam, Blaine R Roberts, Irene Volitakis, Gary F Egan, Catriona A McLean, Roberto Cappai, James A Duce, Ashley I Bush
Nat Med 2012 Jan;
PMID: Object id #33122286308 [PubMed - as supplied by publisher]

Photobiomodulation enhances nigral dopaminergic cell survival in a chronic MPTP mouse model of Parkinson's disease.
Cassandra Peoples, Sharon Spana, Keyoumars Ashkan, Alim-Louis Benabid, Jonathan Stone, Gary E Baker, John Mitrofanis
Parkinsonism Relat Disord 2012 Jan;
PMID: Object id #36922285756 [PubMed - as supplied by publisher]

Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser(19).
Michael F Salvatore, Richard W Davis, Jennifer C Arnold, Tanya Chotibut
Exp Neurol 2012 Jan;
PMID: Object id #41522285253 [PubMed - as supplied by publisher]

Autonomic nervous system as a source of biomarkers in Parkinson's disease.
Hélène Pouclet, Thibaud Lebouvier, Mathurin Flamant, Emmanuel Coron, Michel Neunlist, Pascal Derkinderen, Tiphaine Rouaud
Presse Med 2012 Jan;
PMID: Object id #42422284542 [PubMed - as supplied by publisher]

Antiparkinsonian action of a selective group III mGlu receptor agonist is associated with reversal of subthalamonigral overactivity.
S Lopez, L Jouve, N Turle-Lorenzo, L Kerkerian-Legoff, P Salin, M Amalric
Neurobiol Dis 2012 Jan;
PMID: Object id #182022245662 [PubMed - as supplied by publisher]

Minocycline prevents paraquat-induced cell death through attenuating endoplasmic reticulum stress and mitochondrial dysfunction.
Chuen-Lin Huang, Yi-Chao Lee, Ying-Chen Yang, Tsun-Yung Kuo, Nai-Kuei Huang
Toxicol Lett 2012 Jan; 209(3):203-210
PMID: Object id #185422245251 [PubMed - as supplied by publisher]

15-Deoxy-?12,14-prostaglandin J(2) modulates manganese-induced activation of the NF-?B, Nrf2, and PI3K pathways in astrocytes.
Eunsook Lee, Zhaobao Yin, Marta Sidoryk-W?grzynowicz, Haiyan Jiang, Michael Aschner
Free Radic Biol Med 2011 Dec;
PMID: Object id #193422245093 [PubMed - as supplied by publisher]

Lipopolysaccharide-induced nigral inflammation leads to increased IL-1? tissue content and expression of astrocytic glial cell line-derived neurotrophic factor.
Mahmoud M Iravani, Mona Sadeghian, Clement C M Leung, Sarah Rose, Peter Jenner
Neurosci Lett 2012 Jan;
PMID: Object id #45422281445 [PubMed - as supplied by publisher]

Microarray genomic profile of mitochondrial and oxidant response in manganese chloride treated PC12 cells.
Equar Taka, Elizabeth Mazzio, Karam F A Soliman, R Renee Reams
Neurotoxicology 2012 Jan;
PMID: Object id #48222281203 [PubMed - as supplied by publisher]

Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of ?-synucleinopathy.
Kiren Ubhi, Chandra Inglis, Michael Mante, Christina Patrick, Anthony Adame, Brian Spencer, Edward Rockenstein, Verena May, Juergen Winkler, Eliezer Masliah
Exp Neurol 2012 Jan;
PMID: Object id #49422281106 [PubMed - as supplied by publisher]

Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin.
Michael Lazarou, Seok Min Jin, Lesley A Kane, Richard J Youle
Dev Cell 2012 Jan;
PMID: Object id #52422280891 [PubMed - as supplied by publisher]

Superiority of PLK-2 as ?-synuclein phosphorylating agent relies on unique specificity determinants.
Mauro Salvi, Edlir Trashi, Oriano Marin, Alessandro Negro, Stefania Sarno, Lorenzo A Pinna
Biochem Biophys Res Commun 2012 Jan;
PMID: Object id #175822248692 [PubMed - as supplied by publisher]

Virtual reality as a tool for evaluation of repetitive rhythmic movements in the elderly and Parkinson's disease patients.
Pablo Arias, Verónica Robles-García, Gabriel Sanmartín, Julian Flores, Javier Cudeiro
PLoS One 2012 ; 7(1):e30021
PMID: Object id #56622279559 [PubMed - as supplied by publisher]

Molecular Chaperones in Parkinson's Disease - Present and Future.
Darius Ebrahimi-Fakhari, Lara Wahlster, Pamela J McLean
J Parkinsons Dis 2011 Nov; 1(4):299-320
PMID: Object id #59322279517 [PubMed - as supplied by publisher]

Assessment of cognitive fluctuation in dementia: a systematic review of the literature.
David R Lee, John-Paul Taylor, Alan J Thomas
Int J Geriatr Psychiatry 2012 Jan;
PMID: Object id #61622278997 [PubMed - as supplied by publisher]

Astragaloside IV prevents MPP(+)-induced SH-SY5Y cell death via the inhibition of Bax-mediated pathways and ROS production.
Zhi-Guo Zhang, Lin Wu, Ju-Lei Wang, Jian-Dong Yang, Jing Zhang, Jian Zhang, Li-Hong Li, Yi Xia, Li-Bo Yao, Huai-Zhou Qin, Guo-Dong Gao
Mol Cell Biochem 2012 Jan;
PMID: Object id #63722278385 [PubMed - as supplied by publisher]

Co-occurrence of parkinsonism and dementia in clinical practice : Relevant differential diagnoses.
I Liepelt-Scarfone, M Jamour, W Maetzler
Z Gerontol Geriatr 2012 Jan; 45(1):23-33
PMID: Object id #65322278003 [PubMed - as supplied by publisher]

Role of axonal transport in ALS.
Fumiaki Tanaka, Kensuke Ikenaka, Gen Sobue
Rinsho Shinkeigaku 2011 Nov; 51(11):1189-91
PMID: Object id #71022277530 [PubMed - as supplied by publisher]

Neuropathology.
Yuko Saito, Shigeo Murayama
Rinsho Shinkeigaku 2011 Nov; 51(11):1168-71
PMID: Object id #71122277522 [PubMed - as supplied by publisher]

"Pathophysiology and clinical presentation of Parkinson's disease-up to date" pathomechanisms of Parkinson's disease.
Takafumi Hasegawa
Rinsho Shinkeigaku 2011 Nov; 51(11):1165-7
PMID: Object id #76722277521 [PubMed - as supplied by publisher]

Selective degradation of expanded polyglutamine proteins by their specific recognition with QBP1.
Yoshitaka Nagai, Nobuyuki Nukina
Rinsho Shinkeigaku 2011 Nov; 51(11):1108-10
PMID: Object id #75022277499 [PubMed - as supplied by publisher]

Seed, aggregation and propagation of abnormal proteins could explain neurodegeneration?
Shigeo Murayama
Rinsho Shinkeigaku 2011 Nov; 51(11):1097-9
PMID: Object id #77122277493 [PubMed - as supplied by publisher]

"Atypical" method for understanding dementia. How can studying epigenetics contribute?
Atsushi Iwata
Rinsho Shinkeigaku 2011 Nov; 51(11):928-9
PMID: Object id #78922277421 [PubMed - as supplied by publisher]

Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.
Eisuke Itakura, Chieko Kishi-Itakura, Ikuko Koyama-Honda, Noboru Mizushima
J Cell Sci 2012 Jan;
PMID: Object id #80622275429 [PubMed - as supplied by publisher]

Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: A population-based study.
Brendon P Boot, Bradley F Boeve, Rosebud O Roberts, Tanis J Ferman, Yonas E Geda, V Shane Pankratz, Robert J Ivnik, Glenn E Smith, Eric McDade, Teresa J H Christianson, David S Knopman, Eric G Tangalos, Michael H Silber, Ronald C Petersen
Ann Neurol 2012 Jan; 71(1):49-56
PMID: Object id #83522275251 [PubMed - as supplied by publisher]

Head injury, alpha-synuclein Rep1, and Parkinson's disease.
Samuel M Goldman, Freya Kamel, G Webster Ross, Sarah A Jewell, Grace S Bhudhikanok, David Umbach, Connie Marras, Robert A Hauser, Joseph Jankovic, Stewart A Factor, Susan Bressman, Kelly E Lyons, Cheryl Meng, Monica Korell, Diana F Roucoux, Jane A Hoppin, Dale P Sandler, J William Langston, Caroline M Tanner
Ann Neurol 2012 Jan; 71(1):40-8
PMID: Object id #86522275250 [PubMed - as supplied by publisher]

The chaperone activity of ?-synuclein: Utilizing deletion mutants to map its interaction with target proteins.
Agata Rekas, Keun Jae Ahn, Jongsun Kim, John A Carver
Proteins 2012 Jan;
PMID: Object id #90322274962 [PubMed - as supplied by publisher]

Immunohistochemical localization of X-linked inhibitor of apoptosis protein in brainstem-type and cortical Lewy bodies.
Yasuhiro Kawamoto, Hidefumi Ito, Masafumi Ihara, Ryosuke Takahashi
Neuroreport 2012 Feb; 23(3):162-7
PMID: Object id #92422273571 [PubMed - as supplied by publisher]

Evaluation of the Neurotoxic/Neuroprotective Role of Organoselenides Using Differentiated Human Neuroblastoma SH-SY5Y Cell Line Challenged with 6-Hydroxydopamine.
Fernanda Martins Lopes, Giovana Ferreira Londero, Liana Marengo de Medeiros, Leonardo Lisbôa da Motta, Guilherme Antônio Behr, Valeska Aguiar de Oliveira, Mohammad Ibrahim, José Cláudio Fonseca Moreira, Lisiane de Oliveira Porciúncula, João Batista Teixeira da Rocha, Fábio Klamt
Neurotox Res 2012 Jan;
PMID: Object id #96422271527 [PubMed - as supplied by publisher]

Neddylation positively regulates the ubiquitin E3 ligase activity of parkin.
Ji Won Um, Kyung Ah Han, Eunju Im, Yohan Oh, Kyule Lee, Kwang Chul Chung
J Neurosci Res 2012 Jan;
PMID: Object id #98222271254 [PubMed - as supplied by publisher]

A Pilot Study Examining Associations between DYRK1A and ?-Synuclein Dementias.
Emma L Jones, Dag Aarsland, Elisabet Londos, Clive Ballard
Neurodegener Dis 2012 Jan;
PMID: Object id #102622269890 [PubMed - as supplied by publisher]

A Mechanistic Study of Proteasome Inhibition-Induced Iron Misregulation in Dopamine Neuron Degeneration.
Xu-Ping Li, Wen-Jie Xie, Zhen Zhang, Sagar Kansara, Joseph Jankovic, Wei-Dong Le
Neurosignals 2012 Jan;
PMID: Object id #104022269801 [PubMed - as supplied by publisher]

Clinical Correlates of Apathy in Patients Recently Diagnosed with Parkinson's Disease: The ANIMO Study.
Esther Cubo, Julián Benito-León, Carlos Coronell, Diana Armesto
Neuroepidemiology 2012 ; 38(1):48-55
PMID: Object id #217522236943 [PubMed - as supplied by publisher]

Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.
Adalberto A Castro, Karina Ghisoni, Alexandra Latini, João Quevedo, Carla I Tasca, Rui D S Prediger
Behav Brain Res 2012 Jan;
PMID: Object id #107822266923 [PubMed - as supplied by publisher]

Iron dysregulation in movement disorders.
Petr Dusek, Joseph Jankovic, Weidong Le
Neurobiol Dis 2012 Jan;
PMID: Object id #110522266337 [PubMed - as supplied by publisher]

A neuroprotective role of the human uncoupling protein 2 (hUCP2) in a Drosophila Parkinson's Disease model.
Rafique Islam, Lichuan Yang, Megha Sah, Kavitha Kannan, Denise Anamani, Chibi Vijayan, Jenny Kwok, Marie E Cantino, M Flint Beal, Yih-Woei C Fridell
Neurobiol Dis 2012 Jan;
PMID: Object id #113122266335 [PubMed - as supplied by publisher]

Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP(+)-induced human neuroblastoma SH-SY5Y cell death.
Guoqi Zhu, Xuncui Wang, Shengbing Wu, Qinglin Li
Neurochem Int 2012 Jan;
PMID: Object id #116822265823 [PubMed - as supplied by publisher]

Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb.
Lisa Glasl, Karina Kloos, Florian Giesert, Anne Roethig, Barbara Di Benedetto, Ralf Kühn, Jingzhong Zhang, Ulrich Hafen, Julia Zerle, Andreas Hofmann, Martin Hrabé de Angelis, Konstanze F Winklhofer, Sabine M Hölter, Daniela M Vogt Weisenhorn, Wolfgang Wurst
Exp Neurol 2012 Jan;
PMID: Object id #122422265660 [PubMed - as supplied by publisher]

MicroRNAs in Parkinson's disease.
M Maral Mouradian
Neurobiol Dis 2012 Jan;
PMID: Object id #191522245218 [PubMed - as supplied by publisher]

Use of viral vectors to create animal models for Parkinson's disease.
Karin Löw, Patrick Aebischer
Neurobiol Dis 2011 Dec;
PMID: Object id #238122227451 [PubMed - as supplied by publisher]

No evidence for differential methylation of ?-synuclein in leukocyte DNA of Parkinson's Disease patients.
Julia Richter, Silke Appenzeller, Ole Ammerpohl, G Deuschl, Steffen Paschen, Norbert Brüggemann, Christine Klein, Gregor Kuhlenbäumer
Mov Disord 2012 Jan;
PMID: Object id #125222262231 [PubMed - as supplied by publisher]

Differential Diagnosis in Alzheimer's Disease and Dementia with Lewy Bodies via VMAT2 and Amyloid Imaging.
Victor L Villemagne, Nobuyuki Okamura, Svetlana Pejoska, John Drago, Rachel S Mulligan, Gaël Chételat, Graeme O'Keefe, Gareth Jones, Hank F Kung, Michael Pontecorvo, Colin L Masters, Daniel M Skovronsky, Christopher C Rowe
Neurodegener Dis 2012 Jan;
PMID: Object id #130722261520 [PubMed - as supplied by publisher]

Effects of Exercise and B Vitamins on Homocysteine and Glutathione in Parkinson's Disease: A Randomized Trial.
Joanne Difrancisco-Donoghue, Eric M Lamberg, Ely Rabin, Ahmed Elokda, Enrico Fazzini, William G Werner
Neurodegener Dis 2012 Jan;
PMID: Object id #136822261439 [PubMed - as supplied by publisher]

Update on Genetics of Parkinsonism.
Shinsuke Fujioka, Zbigniew K Wszolek
Neurodegener Dis 2012 Jan;
PMID: Object id #137022261420 [PubMed - as supplied by publisher]

Mechanisms of protein oligomerization: In-hibitor of functional amyloids templates a-synuclein fibrilla-tion.
Istvan Horvath, Christoph Felix Weise, Emma K Andersson, Erik Chorell, Magnus Sellstedt, Christoffer Bengtsson, Anders Olofsson, Scott J Hultgren, Matthew R Chapman, Magnus Wolf-Watz, Fredrik Almqvist, Pernilla El Wittung-Stafshede
J Am Chem Soc 2012 Jan;
PMID: Object id #140422260746 [PubMed - as supplied by publisher]

Sustained expression of PGC-1? in the rat nigrostriatal system selectively impairs dopaminergic function.
C Ciron, S Lengacher, J Dusonchet, P Aebischer, B L Schneider
Hum Mol Genet 2012 Jan;
PMID: Object id #180322246294 [PubMed - as supplied by publisher]

Elevated Levels of ?-Synuclein Oligomer in the Cerebrospinal Fluid of Drug-Naïve Patients with Parkinson's Disease.
Min Jeong Park, Sang-Myung Cheon, Hye-Ran Bae, Sang-Ho Kim, Jae Woo Kim
J Clin Neurol 2011 Dec; 7(4):215-22
PMID: Object id #142422259618 [PubMed - as supplied by publisher]

Neuronal Autophagy and Neurodegenerative Diseases.
Jin H Son, Jung Hee Shim, Kyung Hee Kim, Ji Young Ha, Ji Young Han
Exp Mol Med 2012 Jan;
PMID: Object id #145822257884 [PubMed - as supplied by publisher]

Video assessment of finger tapping for Parkinson's disease and other movement disorders.
Kjersten Criss, James McNames
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:7123-6
PMID: Object id #147622255980 [PubMed - as supplied by publisher]

Capturing whole-body mobility of patients with Parkinson disease using inertial motion sensors: Expected challenges and rewards.
Fariborz Rahimi, Christian Duval, Mandar Jog, Carina Bee, Angela South, Monica Jog, Roderick Edwards, Patrick Boissy
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:5833-8
PMID: Object id #151222255666 [PubMed - as supplied by publisher]

Emerging techniques for elucidating mechanism of action of deep brain stimulation.
Kendall H Lee, Su-Youne Chang, Dong-Pyo Jang, Inyong Kim, Stephan Goerss, Jamie Van Gompel, Paul Min, Kanika Arora, Michael Marsh, Sun Chul Hwang, Christopher J Kimble, Paul Garris, Charles Blaha, Kevin E Bennet
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:677-80
PMID: Object id #153722254400 [PubMed - as supplied by publisher]

The translational value of the MPTP non-human primate model of Parkinsonism for deep brain stimulation research.
Peter A Tass, Li Qin, Christian Hauptmann, Sandra Dovero, Erwan Bezard, Thomas Boraud, Wassilios G Meissner
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:663-6
PMID: Object id #156022254396 [PubMed - as supplied by publisher]

The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease.
Edward C Lauterbach, Leonardo F Fontenelle, Antonio L Teixeira
Parkinsons Dis 2012 ; 2012:753548
PMID: Object id #158022254151 [PubMed - as supplied by publisher]

Apoptosis Signal-Regulating Kinase 1 Mediates MPTP Toxicity and Regulates Glial Activation.
Kang-Woo Lee, Xin Zhao, Joo-Young Im, Hilary Grosso, Won Hee Jang, Teresa W Chan, Patricia K Sonsalla, Dwight C German, Hidenori Ichijo, Eunsung Junn, M Maral Mouradian
PLoS One 2012 ; 7(1):e29935
PMID: Object id #160622253830 [PubMed - as supplied by publisher]

Reduction of Mitoferrin Results in Abnormal Development and Extended Lifespan in Caenorhabditis elegans.
Yaguang Ren, Su Yang, Guoqiang Tan, Wei Ye, Danhui Liu, Xu Qian, Zhongying Ding, Yuhong Zhong, Jingrui Zhang, Dandan Jiang, Yuhong Zhao, Jianxin Lu
PLoS One 2012 ; 7(1):e29666
PMID: Object id #164022253756 [PubMed - as supplied by publisher]

Animal models of Parkinson's disease.
Fabio Blandini, Marie-Therese Armentero
FEBS J 2012 Jan;
PMID: Object id #167222251459 [PubMed - as supplied by publisher]

Role of ?-synuclein penetration into the membrane in the mechanisms of oligomer pore formation.
Igor F Tsigelny, Yuriy Sharikov, Wolfgang Wrasidlo, Tania Gonzalez, Paula A Desplats, Leslie Crews, Brian Spencer, Eliezer Masliah
FEBS J 2012 Jan;
PMID: Object id #170522251432 [PubMed - as supplied by publisher]

Toxic effects of nicotinamide methylation on mouse brain striatum neuronal cells and its relation to manganese.
Yayoi Mori, Akiko Sugawara, Masayoshi Tsuji, Takeyasu Kakamu, Satoshi Tsuboi, Hideyuki Kanda, Takehito Hayakawa, Tetsuhito Fukushima
Environ Health Prev Med 2012 Jan;
PMID: Object id #172122249857 [PubMed - as supplied by publisher]

HtrA2/Omi is Involved in 6-OHDA-Induced Endoplasmic Reticulum Stress in SH-SY5Y Cells.
Feifei Luo, Lei Wei, Congcong Sun, Xiaowu Chen, Tan Wang, Yi Li, Zhuolin Liu, Zhibin Chen, Pingyi Xu
J Mol Neurosci 2012 Jan;
PMID: Object id #178222246992 [PubMed - as supplied by publisher]

Involvement of NADPH oxidase and glutathione in zinc-induced dopaminergic neurodegeneration in rats: Similarity with paraquat neurotoxicity.
Ashutosh Kumar, Brajesh Kumar Singh, Israr Ahmad, Smriti Shukla, Devendra Kumar Patel, Garima Srivastava, Vinod Kumar, Haushila Prasad Pandey, Chetna Singh
Brain Res 2011 Dec;
PMID: Object id #193822244881 [PubMed - as supplied by publisher]

Lewy body-related ?-synucleinopathy in the spinal cord of cases with incidental Lewy body disease.
Takuya Tamura, Mari Yoshida, Yoshio Hashizume, Gen Sobue
Neuropathology 2012 Feb; 32(1):13-22
PMID: Object id #197122243359 [PubMed - as supplied by publisher]

The role of mitochondrial dynamics in neurodegeneration].
Wen-Wei Li, Min Zhu, Chuan-Zhen Lv
Sheng Li Ke Xue Jin Zhan 2011 Oct; 42(5):347-52
PMID: Object id #199622242401 [PubMed - as supplied by publisher]

Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease.
Zhi Yao, Sonia Gandhi, Victoria S Burchell, Helene Plun-Favreau, Nicholas W Wood, Andrey Y Abramov
J Cell Sci 2011 Dec; 124(Pt 24):4194-202
PMID: Object id #264122223879 [PubMed - as supplied by publisher]

The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants.
Sven Vilain, Giovanni Esposito, Dominik Haddad, Onno Schaap, Mariya P Dobreva, Melissa Vos, Stefanie Van Meensel, Vanessa A Morais, Bart De Strooper, Patrik Verstreken
PLoS Genet 2012 Jan; 8(1):e1002456
PMID: Object id #201522242018 [PubMed - as supplied by publisher]

Short-term exposure of 4-hydroxynonenal induces mitochondria-mediated apoptosis in PC12 cells.
M A Siddiqui, V Kumar, M P Kashyap, M Agarwal, A K Singh, V K Khanna, A A Al-Khedhairy, J Musarrat, A B Pant, S Jahan
Hum Exp Toxicol 2012 Jan;
PMID: Object id #204822241629 [PubMed - as supplied by publisher]

Plasma and urinary HPLC-ED determination of the ratio of 8-OHdG/2-dG in Parkinson's disease.
A Bolner, M Pilleri, V De Riva, G P Nordera
Clin Lab 2011 ; 57(11-12):859-66
PMID: Object id #206322239015 [PubMed - as supplied by publisher]

New pharmacological avenues for the treatment of l-DOPA-induced dyskinesias in Parkinson's disease: targeting glutamate and adenosine receptors.
Fabio Blandini, Marie-Therese Armentero
Expert Opin Investig Drugs 2012 Feb; 21(2):153-68
PMID: Object id #230222233485 [PubMed - as supplied by publisher]

Correction: Redistribution of DAT/?-Synuclein Complexes Visualized by "In Situ" Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease.
Arianna Bellucci, Laura Navarria, Elisa Falarti, Michela Zaltieri, Federica Bono, Ginetta Collo, Maria Grazia Spillantini, Cristina Missale, Pierfranco Spano
PLoS One 2012 ; 7(1)
PMID: Object id #208322238563 [PubMed - as supplied by publisher]

Microtubule affinity regulating kinase 2 (MARK2) turns PTEN-induced kinase 1 (PINK1) on at T313, a mutation site in Parkinson's disease: Effects on mitochondrial transport.
Dorthe Matenia, Cindy Hempp, Thomas Timm, Annika Eikhof, Eva-Maria Mandelkow
J Biol Chem 2012 Jan;
PMID: Object id #212722238344 [PubMed - as supplied by publisher]

Action reprogramming in Parkinson's disease: response to prediction error is modulated by levels of dopamine.
Joseph M Galea, Sven Bestmann, Mazda Beigi, Marjan Jahanshahi, John C Rothwell
J Neurosci 2012 Jan; 32(2):542-50
PMID: Object id #214922238089 [PubMed - as supplied by publisher]

?(9) -THC exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.
Camille B Carroll, Marie-Louise Zeissler, C Oliver Hanemann, John P Zajicek
Neuropathol Appl Neurobiol 2012 Jan;
PMID: Object id #219922236282 [PubMed - as supplied by publisher]

Reduced Content of ?-Synuclein in Peripheral Blood Leukocytes of Patients with LRRK2-Associated Parkinson's Disease.
S N Pchelina, A K Emelyanov, A F Yakimovskii, D W Miller, I G Shabalina, A S Drozdova, A L Schwarzman
Bull Exp Biol Med 2011 Apr; 150(6):679-81
PMID: Object id #222222235415 [PubMed - as supplied by publisher]

Experimental modeling of preclinical and clinical stages of Parkinson's disease.
V G Khaindrava, E A Kozina, V S Kudrin, V G Kucheryanu, P D Klodt, V B Narkevich, E V Bocharov, A K Nanaev, G N Kryzhanovsky, K S Raevskii, M V Ugrumov
Bull Exp Biol Med 2011 Mar; 150(5):566-9
PMID: Object id #224822235385 [PubMed - as supplied by publisher]

CART Peptide Is a Potential Endogenous Antioxidant and Preferentially Localized in Mitochondria.
Peizhong Mao, Charles K Meshul, Philippe Thuillier, Natalie R S Goldberg, P Hemachandra Reddy
PLoS One 2012 ; 7(1):e29343
PMID: Object id #227622235287 [PubMed - as supplied by publisher]

A prolyl oligopeptidase inhibitor, KYP-2047, reduces ?-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.
T T Myöhänen, M J Hannula, R Van Elzen, M Gerard, P Van Der Veken, J A García-Horsman, V Baekelandt, P T Männistö, A M Lambeir
Br J Pharmacol 2012 Jan;
PMID: Object id #232322233220 [PubMed - as supplied by publisher]

SIRT1: new avenues of discovery for disorders of oxidative stress.
Zhao Zhong Chong, Yan Chen Shang, Shaohui Wang, Kenneth Maiese
Expert Opin Ther Targets 2012 Jan;
PMID: Object id #235322233091 [PubMed - as supplied by publisher]

Phosphorylation of ?-synuclein at Ser129 reduces neuronal dysfunction by lowering its membrane-binding property in Caenorhabditis elegans.
Tomoki Kuwahara, Reina Tonegawa, Genta Ito, Shohei Mitani, Takeshi Iwatsubo
J Biol Chem 2012 Jan;
PMID: Object id #237622232559 [PubMed - as supplied by publisher]

Antibody 9D5 Recognizes Oligomeric Pyroglutamate Amyloid-? in a Fraction of Amyloid-? Deposits in Alzheimer's Disease without Cross-Reactivity with other Protein Aggregates.
Vivek Venkataramani, Oliver Wirths, Herbert Budka, Wolfgang Härtig, Gabor G Kovacs, Thomas A Bayer
J Alzheimers Dis 2012 Jan;
PMID: Object id #255722232007 [PubMed - as supplied by publisher]

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway.
Youren Tong, Emilie Giaime, Hiroo Yamaguchi, Takaharu Ichimura, Yumin Liu, Huiqing Si, Huaibin Cai, Joseph V Bonventre, Jie Shen
Mol Neurodegener 2012 Jan; 7(1):2
PMID: Object id #253722230652 [PubMed - as supplied by publisher]

TARGETING MITOCHONDRIA FOR NEUROPROTECTION IN PARKINSON'S DISEASE.
Anthony H V Schapira
Antioxid Redox Signal 2012 Jan;
PMID: Object id #250422229791 [PubMed - as supplied by publisher]

A guide to neurotoxic animal models of Parkinson's disease.
Kim Tieu
Cold Spring Harb Perspect Med 2011 Sep; 1(1):a009316
PMID: Object id #248522229125 [PubMed - as supplied by publisher]

Visual hallucinations in the differential diagnosis of parkinsonism.
Kelly Bertram, David R Williams
J Neurol Neurosurg Psychiatry 2012 Jan;
PMID: Object id #246422228724 [PubMed - as supplied by publisher]

Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity.
Peter Teismann, Kinnari Sathe, Angelika Bierhaus, Lin Leng, Heather L Martin, Richard Bucala, Bernd Weigle, Peter P Nawroth, Jörg B Schulz
Neurobiol Aging 2012 Jan;
PMID: Object id #239422227007 [PubMed - as supplied by publisher]

DNA Repair Genes in Parkinson's Disease.
Mehmet Gencer, Selcuk Dasdemir, Bedia Cakmakoglu, Yilmaz Cetinkaya, Figen Varlibas, Hulya Tireli, Cem Ismail Kucukali, Elif Ozkok, Makbule Aydin
Genet Test Mol Biomarkers 2012 Jan;
PMID: Object id #259422224629 [PubMed - as supplied by publisher]