Causes and Pathology

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Structural Reorganization of alpha-Synuclein at Low pH Observed by NMR and REMD Simulations.
Kuen-Phon Wu, Daniel S Weinstock, Chitra Narayanan, Ronald M Levy, Jean Baum
J Mol Biol 2009 Jul;
PMID: 19576220 [PubMed - as supplied by publisher]

Mitochondrial kinases in Parkinson's disease: Converging insights from neurotoxin and genetic models.
Ruben K Dagda, Jianhui Zhu, Charleen T Chu
Mitochondrion 2009 Jun;
PMID: 19563915 [PubMed - as supplied by publisher]

beta-Sheet-breaking peptides inhibit the fibrillation of human alpha-synuclein.
You Soon Kim, Dongyeol Lim, Joo Yeon Kim, Shin Jung Kang, Yang-Hee Kim, Hana Im
Biochem Biophys Res Commun 2009 Jul;
PMID: 19622344 [PubMed - as supplied by publisher]

Rotenone and paraquat do not directly activate microglia or induce inflammatory cytokine release.
Heather Klintworth, Gwenn Garden, Zhengui Xia
Neurosci Lett 2009 Oct; 462(1):1-5
PMID: 19559752 [PubMed - as supplied by publisher]

Neural cell cycle dysregulation and central nervous system diseases.
Wei Wang, Bitao Bu, Minjie Xie, Min Zhang, Zhiyuan Yu, Deding Tao
Prog Neurobiol 2009 Feb;
PMID: 19619927 [PubMed - as supplied by publisher]

Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial Dysfunction in Alzheimer's and Parkinson's diseases.
Latha Devi, Hindupur K Anandatheerthavarada
Biochim Biophys Acta 2009 Jul;
PMID: 19619643 [PubMed - as supplied by publisher]

Cytotoxicity of dopaminochrome in the mesencephalic cell line, MN9D, is dependent upon oxidative stress.
Andrew J Linsenbardt, Gerald H Wilken, Thomas C Westfall, Heather Macarthur
Neurotoxicology 2009 Jul;
PMID: 19619580 [PubMed - as supplied by publisher]

Threonine 53 in alpha-synuclein is conserved in long-living non-primate animals.
Knud Larsen, Claus Hedegaard, Mads Frost Bertelsen, Christian Bendixen
Biochem Biophys Res Commun 2009 Jul;
PMID: 19619507 [PubMed - as supplied by publisher]

Controlling aggregation propensity in A53T mutant of alpha-synuclein causing Parkinson's disease.
Sonu Kumar, Anita Sarkar, Durai Sundar
Biochem Biophys Res Commun 2009 Jul;
PMID: 19580781 [PubMed - as supplied by publisher]

Neuropathology of Lewy body disorders.
Enikö Kövari, Judit Horvath, Constantin Bouras
Brain Res Bull 2009 Jul;
PMID: 19576266 [PubMed - as supplied by publisher]

The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide.
Diego Albani, Letizia Polito, Sara Batelli, Stefania De Mauro, Claudia Fracasso, Giuliana Martelli, Laura Colombo, Claudia Manzoni, Mario Salmona, Silvio Caccia, Alessandro Negro, Gianluigi Forloni
J Neurochem 2009 Jun;
PMID: 19558452 [PubMed - as supplied by publisher]

Electro-acupuncture stimulation improves motor disorders in Parkinsonian rats.
Jun Jia, Zuoli Sun, Bo Li, Yanli Pan, Haomin Wang, Xuan Wang, Fen Yu, Limin Liu, Lijuan Zhang, Xiaomin Wang
Behav Brain Res 2009 Jun;
PMID: 19549545 [PubMed - as supplied by publisher]

Functional dissection of the alpha-synuclein promoter: transcriptional regulation by ZSCAN21 and ZNF219.
Richard Lee Clough, Georgia Dermentzaki, Leonidas Stefanis
J Neurochem 2009 Jun;
PMID: 19549071 [PubMed - as supplied by publisher]

Chronic, systemic treatment with a metabotropic glutamate receptor 5 antagonist in 6-hydroxydopamine partially lesioned rats reverses abnormal firing of dopaminergic neurons.
Li Chen, Qiao Jun Zhang, Jian Liu, Shuang Wang, Umar Ali, Zhen Hua Gui, Yong Wang
Brain Res 2009 Jun;
PMID: 19545547 [PubMed - as supplied by publisher]

Quantification of Paraquat, MPTP, and MPP(+) in brain tissue using microwave-assisted solvent extraction (MASE) and high-performance liquid chromatography-mass spectrometry.
Bozena Winnik, Dana Barr, Mona Thiruchelvam, M Montesano, Eric Richfield, Brian Buckley
Anal Bioanal Chem 2009 Jul;
PMID: 19618168 [PubMed - as supplied by publisher]

Protection of neurons derived from human neural progenitor cells by veratridine.
Peter Morgan, Stefanie Ortinau, Jana Frahm, Norman Krüger, Arndt Rolfs, Moritz Frech
Neuroreport 2009 Jul;
PMID: 19617853 [PubMed - as supplied by publisher]

Parkin protects Mitochondrial Genome Integrity and supports Mitochondrial DNA Repair.
Oliver Rothfuss, Heike Fischer, Takafumi Hasegawa, Martina Maisel, Petra Leitner, Franziska Miesel, Manu Sharma, Antje Bornemann, Daniela Berg, Thomas Gasser, Nadja Patenge
Hum Mol Genet 2009 Jul;
PMID: 19617636 [PubMed - as supplied by publisher]

Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson's disease.
Tuan Hoang, Dong-Kug Choi, Makiko Nagai, Du-Chu Wu, Tetsuya Nagata, Delphine Prou, Glenn L Wilson, Miquel Vila, Vernice Jackson-Lewis, Valina L Dawson, Ted M Dawson, Marie-Françoise Chesselet, Serge Przedborski
Free Radic Biol Med 2009 Jul;
PMID: 19616617 [PubMed - as supplied by publisher]

Effects of glutamate and alpha2-noradrenergic receptor antagonists on the development of neurotoxicity produced by chronic rotenone in rats.
Mesbah Alam, Wojciech Danysz, Werner Jürgen Schmidt, Andrzej Dekundy
Toxicol Appl Pharmacol 2009 Jul;
PMID: 19616571 [PubMed - as supplied by publisher]

(-)-Epigallocatechin-3-gallate (EGCG) Maintains kappa-Casein In Its Pre-fibrillar State Without Redirecting Its Aggregation Pathway.
Sean A Hudson, Heath Ecroyd, Francis C Dehle, Ian F Musgrave, John A Carver
J Mol Biol 2009 Jul;
PMID: 19616561 [PubMed - as supplied by publisher]

Inhibitors of protein aggregation and toxicity.
Hozefa Amijee, Jill Madine, David A Middleton, Andrew J Doig
Biochem Soc Trans 2009 Aug; 37(Pt 4):692-6
PMID: 19614577 [PubMed - as supplied by publisher]

Protein reactivity of 3,4-dihydroxyphenylacetaldehyde, a toxic dopamine metabolite, is dependent on both the aldehyde and the catechol.
Jennifer N Rees, Virginia R Florang, Laurie L Eckert, Jonathan A Doorn
Chem Res Toxicol 2009 Jul; 22(7):1256-63
PMID: 19537779 [PubMed - as supplied by publisher]

Dominant-positive HSF1 decreases alpha-synuclein level and alpha-synuclein-induced toxicity.
Xu Liangliang, Hou Yonghui, E Shunmei, Gong Shoufang, Zhou Wei, Zou Jiangying
Mol Biol Rep 2009 Jul;
PMID: 19609719 [PubMed - as supplied by publisher]

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity.
Dejan Milatovic, Snjezana Zaja-Milatovic, Ramesh C Gupta, Yingchun Yu, Michael Aschner
Toxicol Appl Pharmacol 2009 Jul;
PMID: 19607852 [PubMed - as supplied by publisher]

Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: A biological link between Gaucher disease and parkinsonism.
Amy B Manning-Bo?, Birgitt Schüle, J William Langston
Neurotoxicology 2009 Jul;
PMID: 19576930 [PubMed - as supplied by publisher]

In vitro characterisation of BF227 binding to alpha-synuclein/Lewy bodies.
Michelle T Fodero-Tavoletti, Rachel S Mulligan, Nobuyuki Okamura, Shozo Furumoto, Christopher C Rowe, Yukitsuka Kudo, Colin L Masters, Roberto Cappai, Kazuhiko Yanai, Victor L Villemagne
Eur J Pharmacol 2009 Jul;
PMID: 19576880 [PubMed - as supplied by publisher]

Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications.
Hong Qing, Winnie Wong, Edith G McGeer, Patrick L McGeer
Biochem Biophys Res Commun 2009 Jul;
PMID: 19576176 [PubMed - as supplied by publisher]

Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy.
Patricia A Trimmer, Kathleen M Schwartz, M Kathleen Borland, Luis De Taboada, Jackson Streeter, Uri Oron
Mol Neurodegener 2009 ; 4:26
PMID: 19534794 [PubMed - as supplied by publisher]

DNA Methylation of Alzheimer Disease and Tauopathy-Related Genes in Postmortem Brain.
Marta Barrachina, Isidre Ferrer
J Neuropathol Exp Neurol 2009 Jul;
PMID: 19606065 [PubMed - as supplied by publisher]

JNK inhibitor protects dopaminergic neurons by reducing COX-2 expression in the MPTP mouse model of subacute Parkinson's disease.
Yongsheng Wang, Yuxin Zhang, Zifeng Wei, Hui Li, Hongxia Zhou, Zhiyong Zhang, Zuofeng Zhang
J Neurol Sci 2009 Jul;
PMID: 19604516 [PubMed - as supplied by publisher]

Correction: Dissembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients.
Zhenyu Zhong, Hikmet Nural, Ping He, Gina Civarella, Thomas Beach, Lucia Sue, Charles Adler, Holly Shill, John Caviness, Weiming Xia, Yong Shen
Mol Neurodegener 2009 Jul; 4(1):30
PMID: 19604362 [PubMed - as supplied by publisher]

Frontotemporal lobar degeneration and dementia with Lewy bodies: clinicopathological issues associated with antemortem diagnosis.
Osamu Yokota
Psychogeriatrics 2009 Jun; 9(2):91-102
PMID: 19604332 [PubMed - as supplied by publisher]

Long term high frequency stimulation of STN increases dopamine in the corpus striatum of hemiparkinsonian rhesus monkey.
Xu-Dong Zhao, Yi-Qun Cao, Han-Hua Liu, Feng-Qian Li, Ben-Ming You, Xiao-Ping Zhou
Brain Res 2009 Jun;
PMID: 19563788 [PubMed - as supplied by publisher]

Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease.
Baohua Cheng, Xinxin Yang, Liangxiang An, Bo Gao, Xia Liu, Shuwei Liu
Brain Res 2009 Jun;
PMID: 19559687 [PubMed - as supplied by publisher]

Conditions for Tumor-free and Dopamine Neuron-enriched Grafts After Transplanting Human ES Cell-derived Neural Precursor Cells.
Ji-Yun Ko, Hyun-Seob Lee, Chang-Hwan Park, Hyun-Chul Koh, Yong-Sung Lee, Sang-Hun Lee
Mol Ther 2009 Jul;
PMID: 19603007 [PubMed - as supplied by publisher]

Neuroprotective effects of tetracyclines: molecular targets, animal models and human disease.
D Orsucci, V Calsolaro, M Mancuso, G Siciliano
CNS Neurol Disord Drug Targets 2009 Jun; 8(3):222-31
PMID: 19601819 [PubMed - as supplied by publisher]

p53-Induced Apoptosis and Inhibitors of p53.
Surendra Kumar Nayak, Paramjit Singh Panesar, Harish Kumar
Curr Med Chem 2009 ; 16(21):2627-40
PMID: 19601800 [PubMed - as supplied by publisher]

Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: Common implication of striatal neuropeptides.
Mohamed Khalil Tamim, Pershia Samadi, Marc Morissette, Laurent Grégoire, Bazoumana Ouattara, Daniel Lévesque, Claude Rouillard, Thérèse Di Paolo
Neuropharmacology 2009 Jul;
PMID: 19576910 [PubMed - as supplied by publisher]

Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models.
Joshua A Kritzer, Shusei Hamamichi, J Michael McCaffery, Sandro Santagata, Todd A Naumann, Kim A Caldwell, Guy A Caldwell, Susan Lindquist
Nat Chem Biol 2009 Jul;
PMID: 19597508 [PubMed - as supplied by publisher]

Parkinson disease: extranigral, multisystem, and {alpha}-synuclein "plus".
Michail E Kalaitzakis, Manuel B Graeber, Stephen M Gentleman, Ronald K B Pearce
Arch Neurol 2009 Jul; 66(7):914-5; author reply 915-6
PMID: 19597100 [PubMed - as supplied by publisher]

Elevated serum pesticide levels and risk of Parkinson disease.
Jason R Richardson, Stuart L Shalat, Brian Buckley, Bozena Winnik, Padraig O'Suilleabhain, Ramon Diaz-Arrastia, Joan Reisch, Dwight C German
Arch Neurol 2009 Jul; 66(7):870-5
PMID: 19597089 [PubMed - as supplied by publisher]

The effect of amino acid substitution in the imperfect repeat sequences of alpha-synuclein on fibrillation.
Ryuichi Harada, Natsuki Kobayashi, Jihoon Kim, Chikashi Nakamura, Sung-Woong Han, Kazunori Ikebukuro, Koji Sode
Biochim Biophys Acta 2009 Jul;
PMID: 19596443 [PubMed - as supplied by publisher]

Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology.
Robert E Drolet, Jason R Cannon, Laura Montero, J Timothy Greenamyre
Neurobiol Dis 2009 Jul;
PMID: 19595768 [PubMed - as supplied by publisher]

Tickled PINK1: Mitochondrial homeostasis and autophagy in recessive Parkinsonism.
Charleen T Chu
Biochim Biophys Acta 2009 Jul;
PMID: 19595762 [PubMed - as supplied by publisher]

Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential.
Laetitia Mony, James Nc Kew, Martin J Gunthorpe, Pierre Paoletti
Br J Pharmacol 2009 Jul;
PMID: 19594762 [PubMed - as supplied by publisher]

Calpains as a Target for Therapy of Neurodegenerative Diseases: Putative Role of Lithium.
Antoni Camins, Natalia Crespo-Biel, Félix Junyent, Ester Verdaguer, Anna M Canudas, Mercè Pallàs
Curr Drug Metab 2009 Jun;
PMID: 19594409 [PubMed - as supplied by publisher]

The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinson's disease phenotype and nicotine-mediated neuroprotection.
Seema Singh, Kavita Singh, Devendra Kumar Patel, Chetna Singh, Chandishwar Nath, Vinod Kumar Singh, Raj Kumar Singh, Mahendra Pratap Singh
Rejuvenation Res 2009 Jun; 12(3):185-97
PMID: 19594327 [PubMed - as supplied by publisher]

Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling.
Nina Rawal, Olga Corti, Paola Sacchetti, Hector Osorio-Ardila, Bita Sehat, Alexis Brice, Ernest Arenas
Biochem Biophys Res Commun 2009 Jul;
PMID: 19591802 [PubMed - as supplied by publisher]

Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications.
Jin-Qiang Chen, Patrick R Cammarata, Christopher P Baines, James D Yager
Biochim Biophys Acta 2009 Jun;
PMID: 19559056 [PubMed - as supplied by publisher]

Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment.
Joo-Yong Lee, Hyo Jin Son, Ji Hyun Choi, Eunsil Cho, Jean Kim, Sun Ju Chung, Onyou Hwang, Jae-Young Koh
Brain Res 2009 Jun;
PMID: 19559009 [PubMed - as supplied by publisher]

Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease.
Ming Ming, Xuping Li, Xiaolan Fan, Dehua Yang, Liang Li, Sheng Chen, Qing Gu, Weidong Le
J Transl Med 2009 ; 7:53
PMID: 19558709 [PubMed - as supplied by publisher]

Hydrogen sulfide inhibits MPP(+)-induced apoptosis in PC12 cells.
Wei-Lan Yin, Jian-Qin He, Bi Hu, Zhi-Sheng Jiang, Xiao-Qing Tang
Life Sci 2009 Jun;
PMID: 19540852 [PubMed - as supplied by publisher]

Tranexamic acid protects against rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells.
Hak-Jae Kim, Hae Jeong Park, Hyun Kyung Park, Joo-Ho Chung
Toxicology 2009 Aug; 262(2):171-4
PMID: 19539006 [PubMed - as supplied by publisher]

Behaviour of motor disabilities and appearance of visual hallucinations in patients with Parkinson's disease in a virtual environment.
Giovanni Albani, Giuseppe Riva, Daniel Bulla, Francesco Menegoni, Riccardo Pignatti, Claudio Trotti, Enrico Molinari, Alessandro Mauro
Stud Health Technol Inform 2009 ; 144:204-7
PMID: 19592764 [PubMed - as supplied by publisher]

A single nucleotide polymorphism in the 3'UTR of the SNCA gene encoding alpha-synuclein is a new potential susceptibility locus for Parkinson disease.
Sotiria Sotiriou, Gretchen Gibney, Andreas D Baxevanis, Robert L Nussbaum
Neurosci Lett 2009 Sep; 461(2):196-201
PMID: 19540308 [PubMed - as supplied by publisher]

Dopamine transporter genetic variants and pesticides in Parkinson's disease.
Beate R Ritz, Angelika D Manthripragada, Sadie Costello, Sarah J Lincoln, Matthew J Farrer, Myles Cockburn, Jeff Bronstein
Environ Health Perspect 2009 Jun; 117(6):964-9
PMID: 19590691 [PubMed - as supplied by publisher]

A triple emission fluorescent probe reveals distinctive amyloid fibrillar polymorphism of wild-type -synuclein and its familial Parkinsons disease- mutants.
Maria Soledad Celej, Wouter Caarls, Alexander P Demchenko, Thomas M Jovin
Biochemistry 2009 Jul;
PMID: 19586054 [PubMed - as supplied by publisher]

Binding of Cu(II) to Human alpha-Synucleins: Comparison of Wild Type and the Point Mutations Associated with the Familial Parkinson's Disease.
Lian Hong, John D Simon
J Phys Chem B 2009 Jul; 113(28):9551-61
PMID: 19548659 [PubMed - as supplied by publisher]

Atomic force microscopy analysis of central nervous system cell morphology on silicon carbide and diamond substrates.
C L Frewin, M Jaroszeski, E Weeber, K E Muffly, A Kumar, M Peters, A Oliveros, S E Saddow
J Mol Recognit 2009 Jul;
PMID: 19585542 [PubMed - as supplied by publisher]

Neuropathology and the Neuroinflammation Idea.
Robert E Mrak
J Alzheimers Dis 2009 Jul;
PMID: 19584454 [PubMed - as supplied by publisher]

Doxycycline is Neuroprotective Against Nigral Dopaminergic Degeneration by a Dual Mechanism Involving MMP-3.
Yuri Cho, Hyo Son, Eun-Mee Kim, Ji Choi, Sung Kim, In Ji, Dong Choi, Tong Joh, Yoon Kim, Onyou Hwang
Neurotox Res 2009 Jul;
PMID: 19582534 [PubMed - as supplied by publisher]

Induction of heat shock protein 70 reduces the alteration of striatal electrical activity caused by mitochondrial impairment.
Michela Tantucci, Giuseppina Mariucci, Elena Taha, Cristiano Spaccatini, Alessandro Tozzi, Elisa Luchetti, Paolo Calabresi, Maria Vittoria Ambrosini
Neuroscience 2009 Jul;
PMID: 19580850 [PubMed - as supplied by publisher]

Plasmalogens as a marker of elevated systemic oxidative stress in Parkinson's disease.
Charalampos Dragonas, Thomas Bertsch, Cornel C Sieber, Thorolf Brosche
Clin Chem Lab Med 2009 ; 47(7):894-7
PMID: 19575554 [PubMed - as supplied by publisher]

Fucoidan protects against dopaminergic neuron death in vivo and in vitro.
Dingzhen Luo, Quanbin Zhang, Haomin Wang, Yanqiu Cui, Zuoli Sun, Jian Yang, Yan Zheng, Jun Jia, Fen Yu, Xuan Wang, Xiaomin Wang
Eur J Pharmacol 2009 Jun;
PMID: 19545563 [PubMed - as supplied by publisher]

Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease.
Sehee Kim, Minho Moon, Seungjoon Park
J Endocrinol 2009 Jul;
PMID: 19570816 [PubMed - as supplied by publisher]

Enhanced alpha-Synuclein Expression in Human Neurodegenerative Diseases: Pathogenetic and Therapeutic Implications.
Alison L McCormack, Donato A Di Monte
Curr Protein Pept Sci 2009 Oct;
PMID: 19538156 [PubMed - as supplied by publisher]

Correlations between gray matter reductions and cognitive deficits in dementia with Lewy Bodies and Parkinson's disease with dementia.
Cristina Sanchez-Castaneda, Ramon Rene, Blanca Ramirez-Ruiz, Jaume Campdelacreu, Jordi Gascon, Carles Falcon, Matilde Calopa, Serge Jauma, Montserrat Juncadella, Carme Junque
Mov Disord 2009 Jun;
PMID: 19569130 [PubMed - as supplied by publisher]

Study on the mechanism of electroacupuncture scalp point penetration therapy in action on apoptosis in the Parkinson's disease rat model
Shun Wang, Hua Jiang, Long Qu
Zhongguo Zhen Jiu 2009 Apr; 29(4):309-13
PMID: 19565741 [PubMed - as supplied by publisher]

Sudomotor, skin vasomotor, and cardiovascular reflexes in 3 clinical forms of Lewy body disease.
Y Akaogi, M Asahina, Y Yamanaka, Y Koyama, T Hattori
Neurology 2009 Jul; 73(1):59-65
PMID: 19564585 [PubMed - as supplied by publisher]

Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusions.
Elisa A Waxman, Jason P Covy, Irene Bukh, Xiaojie Li, Ted M Dawson, Benoit I Giasson
J Neuropathol Exp Neurol 2009 Jul; 68(7):785-96
PMID: 19535993 [PubMed - as supplied by publisher]

The nigrostriatal pathway in Creutzfeldt-Jakob disease.
Anne Vital, Pierre-Olivier Fernagut, Marie-Hélène Canron, Julien Joux, Erwan Bezard, Marie-Laure Martin-Negrier, Claude Vital, François Tison
J Neuropathol Exp Neurol 2009 Jul; 68(7):809-15
PMID: 19535991 [PubMed - as supplied by publisher]

Lewy body pathology in normal elderly subjects.
William R Markesbery, Gregory A Jicha, Huaichen Liu, Frederick A Schmitt
J Neuropathol Exp Neurol 2009 Jul; 68(7):816-22
PMID: 19535990 [PubMed - as supplied by publisher]

Association of DRD3 and GRIN2B with impulse control and related behaviors in Parkinson's disease.
Jee-Young Lee, Eun Kyung Lee, Sung Sup Park, Ji-Yeon Lim, Hee Jin Kim, Ji Sun Kim, Beom S Jeon
Mov Disord 2009 Jun;
PMID: 19562769 [PubMed - as supplied by publisher]

Incidental Lewy body disease: Do some cases represent a preclinical stage of dementia with Lewy bodies?
Roberta Frigerio, Hiroshige Fujishiro, Tae-Beom Ahn, Keith A Josephs, Demetrius M Maraganore, Anthony Delledonne, Joseph E Parisi, Kevin J Klos, Bradley F Boeve, Dennis W Dickson, J Eric Ahlskog
Neurobiol Aging 2009 Jun;
PMID: 19560232 [PubMed - as supplied by publisher]

Pharmacological management of psychosis in elderly patients with parkinsonism.
Mehrul Hasnain, W Victor R Vieweg, Mark S Baron, Mary Beatty-Brooks, Antony Fernandez, Anand K Pandurangi
Am J Med 2009 Jul; 122(7):614-22
PMID: 19559160 [PubMed - as supplied by publisher]

alphaA-crystallin and alphaB-crystallin, newly identified interaction proteins of protease-activated receptor-2 (PAR-2), rescue astrocytes from C2-ceramide- and staurosporine-induced cell death.
Rongyu Li, Tanuja Rohatgi, Theodor Hanck, Georg Reiser
J Neurochem 2009 Jun;
PMID: 19558454 [PubMed - as supplied by publisher]

NITRIC OXIDE IN CELL SURVIVAL: A JANUS MOLECULE.
Vittorio Calabrese, Carolin Cornelius, Enrico Rizzarelli, Joshua B Owen, Albena T Dinkova-Kostova, D Allan Butterfield
Antioxid Redox Signal 2009 Jun;
PMID: 19558211 [PubMed - as supplied by publisher]

p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis.
Anna Nogalska, Chiara Terracciano, Carla D'Agostino, W King Engel, Valerie Askanas
Acta Neuropathol 2009 Jun;
PMID: 19557423 [PubMed - as supplied by publisher]

Etiology and pathogenesis of Parkinson disease.
Anthony H V Schapira
Neurol Clin 2009 Aug; 27(3):583-603, v
PMID: 19555823 [PubMed - as supplied by publisher]

Autophagy in neurodegeneration: fire-fighter and/or incendiarist?
Abdelhaq Rami
Neuropathol Appl Neurobiol 2009 Jun;
PMID: 19555462 [PubMed - as supplied by publisher]

Structural characterization of alpha-synuclein in an aggregation prone state.
Min-Kyu Cho, Gabrielle Nodet, Hai-Young Kim, Malene R Jensen, Pau Bernado, Claudio O Fernandez, Stefan Becker, Martin Blackledge, Markus Zweckstetter
Protein Sci 2009 Jun;
PMID: 19554627 [PubMed - as supplied by publisher]

{alpha}-synuclein and Its A30P Mutant Affect Actin Cytoskeletal Structure and Dynamics.
Vítor L Sousa, Serena Bellani, Maila Giannandrea, Malikmohamed Yousuf, Flavia Valtorta, Jacopo Meldolesi, Evelina Chieregatti
Mol Biol Cell 2009 Jun;
PMID: 19553474 [PubMed - as supplied by publisher]

Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity.
Tonya N Taylor, W Michael Caudle, Kennie R Shepherd, AliReza Noorian, Chad R Jackson, P Michael Iuvone, David Weinshenker, James G Greene, Gary W Miller
J Neurosci 2009 Jun; 29(25):8103-13
PMID: 19553450 [PubMed - as supplied by publisher]

"Parkinson-dementia" diseases: A comparison by double tracer SPECT studies.
Carlo Rossi, Duccio Volterrani, Valentina Nicoletti, Gianpiero Manca, Daniela Frosini, Lorenzo Kiferle, Elisa Unti, Paola De Feo, Ubaldo Bonuccelli, Roberto Ceravolo
Parkinsonism Relat Disord 2009 Jun;
PMID: 19553153 [PubMed - as supplied by publisher]

Role of Synucleins in Alzheimer's Disease.
Leslie Crews, Igor Tsigelny, Makoto Hashimoto, Eliezer Masliah
Neurotox Res 2009 Jun;
PMID: 19551456 [PubMed - as supplied by publisher]

CXCR4 and CXCL12 Expression is Increased in the Nigro-Striatal System of Parkinson's Disease.
Mika Shimoji, Fernando Pagan, Edward Healton, Italo Mocchetti
Neurotox Res 2009 Jun;
PMID: 19551455 [PubMed - as supplied by publisher]

Protective effects of a flavonoid-rich extract of Hypericum perforatum L. against hydrogen peroxide-induced apoptosis in PC12 cells.
Yan-Ping Zou, Yan-Hua Lu, Dong-Zhi Wei
Phytother Res 2009 Jun;
PMID: 19548287 [PubMed - as supplied by publisher]

Mitochondrial Superoxide Radicals Differentially Impacts Muscle Activity and Neural Functions in Drosophila.
Tanja Godenschwege, Renee Forde, Claudette Davis, Anirban Paul, Kristopher Beckwith, Atanu Duttaroy
Genetics 2009 Jun;
PMID: 19546321 [PubMed - as supplied by publisher]

The Neurodegenerative Mitochondriopathies.
Russell H Swerdlow
J Alzheimers Dis 2009 Jun;
PMID: 19542616 [PubMed - as supplied by publisher]

Total Prion Protein Levels in the Cerebrospinal Fluid are Reduced in Patients with Various Neurological Disorders.
Felix Meyne, Sara Friederike Gloeckner, Barbara Ciesielczyk, Uta Heinemann, Anna Krasnianski, Bettina Meissner, Inga Zerr
J Alzheimers Dis 2009 Jun;
PMID: 19542614 [PubMed - as supplied by publisher]

Glutathione--a review on its role and significance in Parkinson's disease.
Heather L Martin, Peter Teismann
FASEB J 2009 Jun;
PMID: 19542204 [PubMed - as supplied by publisher]

Biophysics of Parkinson's Disease: Structure and Aggregation of alpha-Synuclein.
Vladimir N Uversky, David Eliezer
Curr Protein Pept Sci 2009 Oct;
PMID: 19538146 [PubMed - as supplied by publisher]

Novel Neuroprotective Mechanisms of Memantine: Increase in Neurotrophic Factor Release from Astroglia and Anti-Inflammation by Preventing Microglial Activation.
Hung-Ming Wu, Nian-Sheng Tzeng, Li Qian, Sung-Jen Wei, Xiaoming Hu, Shih-Heng Chen, Scott M Rawls, Patrick Flood, Jau-Shyong Hong, Ru-Band Lu
Neuropsychopharmacology 2009 Jun;
PMID: 19536110 [PubMed - as supplied by publisher]

Short-term depression of synaptic transmission during stimulation in the globus pallidus of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates.
Yaara Erez, Hadass Czitron, Kevin McCairn, Katya Belelovsky, Izhar Bar-Gad
J Neurosci 2009 Jun; 29(24):7797-802
PMID: 19535591 [PubMed - as supplied by publisher]

Activation of phosphatidylinositol-linked D1-like receptor modulates FGF-2 expression in astrocytes via IP3-dependent Ca2+ signaling.
Xinhua Zhang, Zheng Zhou, Dakui Wang, Aiqun Li, Yanqing Yin, Xiaosong Gu, Fei Ding, Xuechu Zhen, Jiawei Zhou
J Neurosci 2009 Jun; 29(24):7766-75
PMID: 19535588 [PubMed - as supplied by publisher]

Age-related changes in glutamate release in the CA3 and dentate gyrus of the rat hippocampus.
Michelle L Stephens, Jorge E Quintero, Francois Pomerleau, Peter Huettl, Greg A Gerhardt
Neurobiol Aging 2009 Jun;
PMID: 19535175 [PubMed - as supplied by publisher]

The Pro-apoptotic Substance Thapsigargin Selectively Stimulates Re-growth of Brain Capillaries.
Celine Ullrich, Christian Humpel
Curr Neurovasc Res 2009 Aug;
PMID: 19534719 [PubMed - as supplied by publisher]

Mutations in the Parkinson's disease genes, Leucine Rich Repeat Kinase 2 (LRRK2) and Glucocerebrosidase (GBA), are not associated with essential tremor.
Lorraine N Clark, Sergey Kisselev, Naeun Park, Barbara Ross, Miguel Verbitsky, Eileen Rios, Roy N Alcalay, Joseph H Lee, Elan D Louis
Parkinsonism Relat Disord 2009 Jun;
PMID: 19527940 [PubMed - as supplied by publisher]

No Lewy pathology in monkeys with over 10 years of severe MPTP Parkinsonism.
Glenda Halliday, Maria Trinidad Herrero, Karen Murphy, Heather McCann, Francisco Ros-Bernal, Carlos Barcia, Hideo Mori, Francisco J Blesa, José A Obeso
Mov Disord 2009 Jun;
PMID: 19526568 [PubMed - as supplied by publisher]

Progressive Dopaminergic Degeneration in the Chronic MPTPp Mouse Model of Parkinson's Disease.
Nicoletta Schintu, Lucia Frau, Marcello Ibba, Arianna Garau, Ezio Carboni, Anna R Carta
Neurotox Res 2009 Aug; 16(2):127-39
PMID: 19526289 [PubMed - as supplied by publisher]