Causes and Pathology

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Deprenyl Enhances the Teratogenicity of Hydroxyurea in Organogenesis Stage Mouse Embryos.
Ava E Schlisser, Barbara F Hales
Toxicol Sci 2013 May;
PMID: Object id #295823696560 [PubMed - as supplied by publisher]

Neuroprotective effect of EGb761(R) and low-dose whole-body ?-irradiationin a rat model of Parkinson's disease.
Mona A El-Ghazaly, Nermin A H Sadik, Engy R Rashed, Amal A Abd El-Fattah
Toxicol Ind Health 2013 May;
PMID: Object id #298023696346 [PubMed - as supplied by publisher]

Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan.
Anil Rana, Michael Rera, David W Walker
Proc Natl Acad Sci U S A 2013 May; 110(21):8638-43
PMID: Object id #66523650379 [PubMed - as supplied by publisher]

?-lipoic acid protects dopaminergic neurons against MPP+-induced apoptosis by attenuating reactive oxygen species formation.
Da-Wei Li, Guang-Ren Li, Yan Lu, Zhi-Qiang Liu, Ming Chang, Ming Yao, Wei Cheng, Lin-Sen Hu
Int J Mol Med 2013 Jul; 32(1):108-14
PMID: Object id #228823615851 [PubMed - as supplied by publisher]

Inhibition of formation of ?-synuclein inclusions by mannosylglycerate in a yeast model of Parkinson's disease.
Cristiana Faria, Carla D Jorge, Nuno Borges, Sandra Tenreiro, Tiago F Outeiro, Helena Santos
Biochim Biophys Acta 2013 Apr; 1830(8):4065-4072
PMID: Object id #239723608058 [PubMed - as supplied by publisher]

Intact olfaction in a mouse model of multiple system atrophy.
Florian Krismer, Gregor K Wenning, Yuntao Li, Werner Poewe, Nadia Stefanova
PLoS One 2013 ; 8(5):e64625
PMID: Object id #300423691255 [PubMed - as supplied by publisher]

Evaluation of Nigrostriatal Neurodegeneration and Neuroinflammation Following Repeated Intranasal 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Administration in Mice, an Experimental Model of Parkinson's Disease.
Fabrine S M Tristão, Majid Amar, Ines Latrous, Elaine A Del-Bel, Rui D Prediger, Rita Raisman-Vozari
Neurotox Res 2013 May;
PMID: Object id #294623690159 [PubMed - as supplied by publisher]

Antagonism of L-type Ca(2+) channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics.
Soosung Kang, Garry Cooper, Sara Fernandez Dunne, Chi-Hao Luan, D James Surmeier, Richard B Silverman
Bioorg Med Chem 2013 Apr;
PMID: Object id #291823688558 [PubMed - as supplied by publisher]

RNA interference targeting ?-synuclein attenuates methamphetamine-induced neurotoxicity in SH-SY5Y cells.
Ling Chen, Enping Huang, Huijun Wang, Pingming Qiu, Chao Liu
Brain Res 2013 May;
PMID: Object id #289023688541 [PubMed - as supplied by publisher]

Glutathione metabolism and Parkinson disease.
Michelle Smeyne, Richard Jay Smeyne
Free Radic Biol Med 2013 May;
PMID: Object id #31523665395 [PubMed - as supplied by publisher]

FBXO7 Immunoreactivity in ?-Synuclein-Containing Inclusions in Parkinson Disease and Multiple System Atrophy.
Tianna Zhao, Lies-Anne Severijnen, Marcel van der Weiden, Ping Pin Zheng, Ben A Oostra, Renate K Hukema, Rob Willemsen, Johan M Kros, Vincenzo Bonifati
J Neuropathol Exp Neurol 2013 Jun; 72(6):482-8
PMID: Object id #58823656991 [PubMed - as supplied by publisher]

Insights into mitochondrial quality control pathways and Parkinson's disease.
Susann Lehmann, L Miguel Martins
J Mol Med (Berl) 2013 Jun; 91(6):665-71
PMID: Object id #91623644494 [PubMed - as supplied by publisher]

Celastrol protects human neuroblastoma SH-SY5Y cells from rotenone-induced injury through induction of autophagy.
Yong-Ning Deng, Jie Shi, Jie Liu, Qiu-Min Qu
Neurochem Int 2013 Apr; 63(1):1-9
PMID: Object id #221323619395 [PubMed - as supplied by publisher]

alpha-Synuclein and intracellular trafficking: impact on the spreading of Parkinson's disease pathology.
Sibylle E Eisbach, Tiago F Outeiro
J Mol Med (Berl) 2013 Jun; 91(6):693-703
PMID: Object id #226623616088 [PubMed - as supplied by publisher]

Complexity of dopamine metabolism.
Johannes Meiser, Daniel Weindl, Karsten Hiller
Cell Commun Signal 2013 May; 11(1):34
PMID: Object id #286123683503 [PubMed - as supplied by publisher]

NF-?B activity is inversely correlated to RNF11 expression in Parkinson's disease.
Elaine Pranski, Carson D Van Sanford, Nirjari Dalal, Adam L Orr, Dipan Karmali, Deborah S Cooper, Marla Gearing, James J Lah, Allan I Levey, Ranjita Betarbet
Neurosci Lett 2013 May;
PMID: Object id #1123669642 [PubMed - as supplied by publisher]

Secalonic acid A protects dopaminergic neurons from 1-methyl-4-phenylpyridinium (MPP(+))-induced cell death via the mitochondrial apoptotic pathway.
Aifeng Zhai, Xiaonan Zhu, Xuelan Wang, Ruzhu Chen, Hai Wang
Eur J Pharmacol 2013 May;
PMID: Object id #33923665112 [PubMed - as supplied by publisher]

Parkinson's disease cybrids, differentiated or undifferentiated, maintain morphological and biochemical phenotypes different from those of control cybrids.
T A Appukuttan, N Ali, M Varghese, A Singh, D Tripathy, M Padmakumar, P K Gangopadhyay, K P Mohanakumar
J Neurosci Res 2013 Jul; 91(7):963-70
PMID: Object id #60823653325 [PubMed - as supplied by publisher]

Lack of effect of ceftriaxone, a GLT-1 transporter activator, on spatial memory in mice.
Ipek Karaman, Gulnur Kizilay-Ozfidan, C Hakan Karadag, Ahmet Ulugol
Pharmacol Biochem Behav 2013 Apr; 108C:61-65
PMID: Object id #171923628489 [PubMed - as supplied by publisher]

Structures and Free Energy Landscapes of the A53T Mutant-Type ?-Synuclein Protein and Impact of A53T Mutation on the Structures of the Wild-Type ?-Synuclein Protein with Dynamics.
Orkid Coskuner, Olivia Wise-Scira
ACS Chem Neurosci 2013 May;
PMID: Object id #242623607785 [PubMed - as supplied by publisher]

Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies.
Claudia Manzoni, Patrick A Lewis
FASEB J 2013 May;
PMID: Object id #283723682122 [PubMed - as supplied by publisher]

Pramipexole Reduces Phosphorylation of ?-Synuclein at Serine-129.
Kai-Yin Chau, J Mark Cooper, Anthony Henry V Schapira
J Mol Neurosci 2013 May;
PMID: Object id #281523681749 [PubMed - as supplied by publisher]

Neuropsychiatric Symptoms in Patients with Dementias Associated with Cortical Lewy Bodies: Pathophysiology, Clinical Features, and Pharmacological Management.
Clive Ballard, Dag Aarsland, Paul Francis, Anne Corbett
Drugs Aging 2013 May;
PMID: Object id #278823681401 [PubMed - as supplied by publisher]

Alpha-Synuclein Overexpression Induced Mitochondrial Damage by the Generation of Endogenous Neurotoxins in PC12 Cells.
Yanyan Zhang, Hong Ma, Bingjie Xie, Chao Han, Chen Wang, Hong Qing, Yulin Deng
Neurosci Lett 2013 May;
PMID: Object id #276523680459 [PubMed - as supplied by publisher]

PLK2 Modulates ?-Synuclein Aggregation in Yeast and Mammalian Cells.
Elisa Basso, Pedro Antas, Zrinka Marijanovic, Susana Gonçalves, Sandra Tenreiro, Tiago Fleming Outeiro
Mol Neurobiol 2013 May;
PMID: Object id #273623677647 [PubMed - as supplied by publisher]

Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson's Disease.
Yang Liu, Yubo Guo, Sai An, Yuyang Kuang, Xi He, Haojun Ma, Jianfeng Li, Jing Lv, Ning Zhang, Chen Jiang
PLoS One 2013 ; 8(5):e62905
PMID: Object id #270923675438 [PubMed - as supplied by publisher]

Somatic alpha-synuclein mutations in Parkinson's disease: Hypothesis and preliminary data.
Christos Proukakis, Henry Houlden, Anthony H Schapira
Mov Disord 2013 May;
PMID: Object id #267523674490 [PubMed - as supplied by publisher]

The many faces of alpha-synuclein mutations.
Meike Kasten, Christine Klein
Mov Disord 2013 May;
PMID: Object id #265123674458 [PubMed - as supplied by publisher]

Correlation between pathology and neuromelanin MR imaging in Parkinson's disease and dementia with Lewy bodies.
Shinichiro Kitao, Eiji Matsusue, Shinya Fujii, Fuminori Miyoshi, Toshio Kaminou, Shinsuke Kato, Hisao Ito, Toshihide Ogawa
Neuroradiology 2013 May;
PMID: Object id #262623673875 [PubMed - as supplied by publisher]

Stem Cells from Wildtype and Friedreich's Ataxia Mice Present Similar Neuroprotective Properties in Dorsal Root Ganglia Cells.
Jonathan Jones, Alicia Estirado, Carolina Redondo, Salvador Martinez
PLoS One 2013 ; 8(5):e62807
PMID: Object id #259523671637 [PubMed - as supplied by publisher]

Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone d is neuroprotective.
Daniele Cartelli, Francesca Casagrande, Carla Letizia Busceti, Domenico Bucci, Gemma Molinaro, Anna Traficante, Daniele Passarella, Erminio Giavini, Gianni Pezzoli, Giuseppe Battaglia, Graziella Cappelletti
Sci Rep 2013 May; 3:1837
PMID: Object id #7723670541 [PubMed - as supplied by publisher]

Oxidative stress in prostate cancer: changing research concepts towards a novel paradigm for prevention and therapeutics.
A Paschos, R Pandya, W C M Duivenvoorden, J H Pinthus
Prostate Cancer Prostatic Dis 2013 May;
PMID: Object id #5223670256 [PubMed - as supplied by publisher]

Neuropsychiatric symptoms in Parkinson disease and dementia with lewy bodies: what geriatric psychiatry can learn.
Daniel Weintraub
Am J Geriatr Psychiatry 2013 Jun; 21(6):497-500
PMID: Object id #11423668226 [PubMed - as supplied by publisher]

Accumulation of Alpha-synuclein Causes Colonic Dysmotility Independently of Enteric Nervous Damage in the Early Stage of Parkinson's Disease (Neurogastroenterol Motil 2012;24:e425-e436).
Yong Sung Kim
J Neurogastroenterol Motil 2013 Apr; 19(2):264-6
PMID: Object id #13523667761 [PubMed - as supplied by publisher]

Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human ?-Synuclein.
Theodore A Sarafian, Christopher M Ryan, Puneet Souda, Eliezer Masliah, Upendra K Kar, Harry V Vinters, Gary W Mathern, Kym F Faull, Julian P Whitelegge, Joseph B Watson
PLoS One 2013 ; 8(5):e63557
PMID: Object id #16123667637 [PubMed - as supplied by publisher]

Could sensory mechanisms be a core factor that underlies freezing of gait in Parkinson's disease?
Kaylena A Ehgoetz Martens, Frederico Pieruccini-Faria, Quincy J Almeida
PLoS One 2013 ; 8(5):e62602
PMID: Object id #19623667499 [PubMed - as supplied by publisher]

An Autopsied Case of Argyrophilic Grain Dementia with Parkinsonism due to Multiple Lacunar Infarctions].
Yasushi Iwasaki, Keiko Mori, Masumi Ito, Akira Deguchi, Shinsui Tatsumi, Maya Mimuro, Mari Yoshida
Brain Nerve 2013 May; 65(5):583-7
PMID: Object id #21923667123 [PubMed - as supplied by publisher]

Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of ?-synuclein in Parkinson's disease models.
Michaeline L Hebron, Irina Lonskaya, Charbel E-H Moussa
Hum Mol Genet 2013 May;
PMID: Object id #24323666528 [PubMed - as supplied by publisher]

Magnetic Resonance Spectroscopy to Assess NeuroInflammation and Neuropathic Pain.
Linda Chang, Sody M Munsaka, Stephanie Kraft-Terry, Thomas Ernst
J Neuroimmune Pharmacol 2013 May;
PMID: Object id #26423666436 [PubMed - as supplied by publisher]

Microfluidic-based Electrotaxis for On-demand Quantitative Analysis of Caenorhabditis elegans' Locomotion.
Justin Tong, Pouya Rezai, Sangeena Salam, P Ravi Selvaganapathy, Bhagwati P Gupta
J Vis Exp 2013 ; (75)
PMID: Object id #29023665669 [PubMed - as supplied by publisher]

Isradipine prevents rotenone-induced intracellular calcium rise that accelerates senescence in human neuroblastoma SH-SY5Y cells.
Xiaohong Yu, Xiaoxiang Li, Genling Jiang, Xuncun Wang, Hebron C Chang, Walter H Hsu, Qinglin Li
Neuroscience 2013 May;
PMID: Object id #36623664925 [PubMed - as supplied by publisher]

A novel ?-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of ?-synuclein-GFP.
Christian Hansen, Tomas Björklund, Geraldine H Petit, Martin Lundblad, Reena Pritu Murmu, Patrik Brundin, Jia-Yi Li
Neurobiol Dis 2013 Apr;
PMID: Object id #92123643841 [PubMed - as supplied by publisher]

Sustained resistance to acute MPTP toxicity by hypothalamic dopamine neurons following chronic neurotoxicant exposure is associated with sustained up-regulation of parkin protein.
Matthew Benskey, Ki Yong Lee, Kevin Parikh, Keith J Lookingland, John L Goudreau
Neurotoxicology 2013 May;
PMID: Object id #97623643664 [PubMed - as supplied by publisher]

Dopaminergic contributions to distance estimation in Parkinson's disease: A sensory-perceptual deficit?
Kaylena A Ehgoetz Martens, Colin G Ellard, Quincy J Almeida
Neuropsychologia 2013 May;
PMID: Object id #99823643554 [PubMed - as supplied by publisher]

Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster.
Jéssie Haigert Sudati, Francielli Araújo Vieira, Sandra Sartoretto Pavin, Glaecir Roseni Mundstock Dias, Rodrigo Lopes Seeger, Ronaldo Golombieski, Margareth Linde Athayde, Félix Antunes Soares, João Batista Teixeira Rocha, Nilda Vargas Barbosa
Neurotoxicology 2013 Apr;
PMID: Object id #109023639798 [PubMed - as supplied by publisher]

Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease.
R St Laurent, L M O'Brien, S T Ahmad
Neuroscience 2013 Apr;
PMID: Object id #206323623990 [PubMed - as supplied by publisher]

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1-/- mice.
Thi A Nguyen, Tamy Frank-Cannon, Terina N Martinez, Kelly A Ruhn, Marian Marvin, Bradford Casey, Isaac Treviño, John J Hong, Matthew S Goldberg, Malú G Tansey
J Neuroinflammation 2013 ; 10(1):50
PMID: Object id #208423622116 [PubMed - as supplied by publisher]

A sigma-1 receptor antagonist (NE-100) prevents tunicamycin-induced cell death via GRP78 induction in hippocampal cells.
Yoko Ono, Hirotaka Tanaka, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara
Biochem Biophys Res Commun 2013 Apr;
PMID: Object id #223823618865 [PubMed - as supplied by publisher]

Autophagic failure promotes the exocytosis and intercellular transfer of ?-synuclein.
He-Jin Lee, Eun-Duk Cho, Kyung Won Lee, Jung-Hyun Kim, Ssang-Goo Cho, Seung-Jae Lee
Exp Mol Med 2013 ; 45:e22
PMID: Object id #39523661100 [PubMed - as supplied by publisher]

Advanced Solid-State NMR Approaches for Structure Determination of Membrane Proteins and Amyloid Fibrils.
Ming Tang, Gemma Comellas, Chad M Rienstra
Acc Chem Res 2013 May;
PMID: Object id #41523659727 [PubMed - as supplied by publisher]

Glutaraldehyde Cross-Linked Glutamate Oxidase Coated Microelectrode Arrays: Selectivity and Resting Levels of Glutamate in the CNS.
Jason J Burmeister, Verda A Davis, Jorge E Quintero, Francois Pomerleau, Peter Huettl, Greg A Gerhardt
ACS Chem Neurosci 2013 May;
PMID: Object id #66423650904 [PubMed - as supplied by publisher]

Mitochondrial dysfunction and oxidative stress in Parkinson's disease.
Sudhakar Raja Subramaniam, Marie-Francoise Chesselet
Prog Neurobiol 2013 Apr;
PMID: Object id #94823643800 [PubMed - as supplied by publisher]

Stimulation of subthalamic nuclei restores a near normal planning strategy in Parkinson's patients.
Giovanni Mirabella, Sara Iaconelli, Nicola Modugno, Giorgio Giannini, Francesco Lena, Gianpaolo Cantore
PLoS One 2013 ; 8(5):e62793
PMID: Object id #46623658775 [PubMed - as supplied by publisher]

Edaravone Prevents Neurotoxicity of Mutant L166P DJ-1 in Parkinson's Disease.
Bing Li, Dawei Yu, Zhiying Xu
J Mol Neurosci 2013 May;
PMID: Object id #55523657982 [PubMed - as supplied by publisher]

Structure-Activity Relationship of N,N'-Disubstituted Pyrimidinetriones as CaV1.3 Channel-Selective Antagonists for Parkinson's Disease.
Soosung Kang, Garry Cooper, Sara Fernandez Dunne, Chi-Hao Luan, D James Surmeier, Richard B Silverman
J Med Chem 2013 May;
PMID: Object id #63823651412 [PubMed - as supplied by publisher]

TFEB-mediated autophagy rescues midbrain dopamine neurons from ?-synuclein toxicity.
Mickael Decressac, Bengt Mattsson, Pia Weikop, Martin Lundblad, Johan Jakobsson, Anders Björklund
Proc Natl Acad Sci U S A 2013 May; 110(19):E1817-26
PMID: Object id #233823610405 [PubMed - as supplied by publisher]

LC/MS characterization of rotenone induced cardiolipin oxidation in human lymphocytes: Implications for mitochondrial dysfunction associated with Parkinson's disease.
Yulia Y Tyurina, Daniel E Winnica, Valentina I Kapralova, Alexandr A Kapralov, Vladimir A Tyurin, Valerian E Kagan
Mol Nutr Food Res 2013 May;
PMID: Object id #71623650208 [PubMed - as supplied by publisher]

Intrabodies as Neuroprotective Therapeutics.
Anne Messer, Shubhada N Joshi
Neurotherapeutics 2013 May;
PMID: Object id #74223649691 [PubMed - as supplied by publisher]

Uridine Prodrug Improves Memory in Tg2576 and TAPP Mice and Reduces Pathological Factors associated with Alzheimer's Disease in Related Models.
Joel A Saydoff, Ana Olariu, Jin Sheng, Zhongyi Hu, Qin Li, Rolando Garcia, Jiong Pei, Grace Y Sun, Reid von Borstel
J Alzheimers Dis 2013 May;
PMID: Object id #73623648515 [PubMed - as supplied by publisher]

The remarkable conformational plasticity of alpha-synuclein: blessing or curse?
Angélique Deleersnijder, Melanie Gerard, Zeger Debyser, Veerle Baekelandt
Trends Mol Med 2013 May;
PMID: Object id #78723648364 [PubMed - as supplied by publisher]

Protein-L-isoaspartate (D-aspartate) O-methyltransferase protects cardiomyocytes against hypoxia induced apoptosis through inhibiting proapoptotic kinase Mst1.
Guijun Yan, Qing Qin, Bing Yi, Kurt Chuprun, Haixiang Sun, Shengdong Huang, Jianxin Sun
Int J Cardiol 2013 May;
PMID: Object id #81623647599 [PubMed - as supplied by publisher]

Severe nigrostriatal degeneration without clinical parkinsonism in patients with polymerase gamma mutations.
Charalampos Tzoulis, Gia Tuong Tran, Thomas Schwarzlmüller, Karsten Specht, Kristoffer Haugarvoll, Novin Balafkan, Peer K Lilleng, Hrvoje Miletic, Martin Biermann, Laurence A Bindoff
Brain 2013 Apr;
PMID: Object id #197223625061 [PubMed - as supplied by publisher]

Tissue distribution profiles of three antiparkinsonian alkaloids from Piper longum L. in rats determined by liquid chromatography-tandem mass spectrometry.
Haolong Liu, Rong Luo, Xiaoqing Chen, Junhui Liu, Ying Bi, Li Zheng, Xia Wu
J Chromatogr B Analyt Technol Biomed Life Sci 2013 Jun; 928:78-82
PMID: Object id #247523603295 [PubMed - as supplied by publisher]

Rotenone Could Activate Microglia Through NF?B Associated Pathway.
Yu-He Yuan, Jian-Dong Sun, Miao-Miao Wu, Jin-Feng Hu, Shan-Ying Peng, Nai-Hong Chen
Neurochem Res 2013 May;
PMID: Object id #84523645222 [PubMed - as supplied by publisher]

Assessing neurodegenerative phenotypes in Drosophila dopaminergic neurons by climbing assays and whole brain immunostaining.
Maria Cecilia Barone, Dirk Bohmann
J Vis Exp 2013 ; (74)
PMID: Object id #86723644755 [PubMed - as supplied by publisher]

Crosstalk between the proteasome system and autophagy in the clearance of ?-synuclein.
Fang Yang, Ya-Ping Yang, Cheng-Jie Mao, Ling Liu, Hui-Fen Zheng, Li-Fang Hu, Chun-Feng Liu
Acta Pharmacol Sin 2013 May; 34(5):674-80
PMID: Object id #251523603979 [PubMed - as supplied by publisher]

Biased Homozygous Haplotypes Across the Human Caveolin 1 Upstream Purine Complex in Parkinson's Disease.
Hossein Darvish, Abolfazl Heidari, Saman Hosseinkhani, Abolfazl Movafagh, Ali Khaligh, Javad Jamshidi, Hamid Noorollahi-Moghaddam, Hamid Reza Heidari-Rostami, Siamak Karkheiran, Gholam-Ali Shahidi, Mansoureh Togha, Seyed Mohammad Hassan Paknejad, Hossein Ashrafian, Siamak Abdi, Saghar Ghasemi Firouzabadi, Seyed Hamid Jamaldini, Mina Ohadi
J Mol Neurosci 2013 May;
PMID: Object id #102723640536 [PubMed - as supplied by publisher]

Nitric oxide and peroxynitrite serum levels in Parkinson's disease: correlation of oxidative stress and the severity of the disease.
L Kouti, M Noroozian, S Akhondzadeh, M Abdollahi, M R Javadi, M A Faramarzi, S Mousavi, P Ghaeli
Eur Rev Med Pharmacol Sci 2013 Apr; 17(7):964-70
PMID: Object id #106523640445 [PubMed - as supplied by publisher]

Native ?-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2.
Jiajie Diao, Jacqueline Burré, Sandro Vivona, Daniel J Cipriano, Manu Sharma, Minjoung Kyoung, Thomas C Südhof, Axel T Brunger
Elife 2013 ; 2:e00592
PMID: Object id #118823638301 [PubMed - as supplied by publisher]

Loss of PINK1 Increases the Heart's Vulnerability to Ischemia-Reperfusion Injury.
Hilary K Siddall, Derek M Yellon, Sang-Bing Ong, Uma A Mukherjee, Niall Burke, Andrew R Hall, Plamena R Angelova, Marthe H R Ludtmann, Emma Deas, Sean M Davidson, Mihaela M Mocanu, Derek J Hausenloy
PLoS One 2013 ; 8(4):e62400
PMID: Object id #123823638067 [PubMed - as supplied by publisher]

Bee Venom and Its Component Apamin as Neuroprotective Agents in a Parkinson Disease Mouse Model.
Daniel Alvarez-Fischer, Carmen Noelker, Franca Vulinovi?, Anne Grünewald, Caroline Chevarin, Christine Klein, Wolfgang H Oertel, Etienne C Hirsch, Patrick P Michel, Andreas Hartmann
PLoS One 2013 ; 8(4):e61700
PMID: Object id #131623637888 [PubMed - as supplied by publisher]

Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants.
Giovanni Esposito, Melissa Vos, Sven Vilain, Jef Swerts, Jorge De Sousa Valadas, Stefanie Van Meensel, Onno Schaap, Patrik Verstreken
PLoS Genet 2013 Apr; 9(4):e1003478
PMID: Object id #134423637640 [PubMed - as supplied by publisher]

A BBB Disrupter is also a Potent ?-Synuclein (?-syn) Aggregation Inhibitor: A Novel Dual Mechanism of Mannitol for the Treatment of Parkinson's Disease (PD).
Ronit Shaltiel-Karyo, Moran Frenkel-Pinter, Edward Rockenstein, Christina Patrick, Michal Levy-Sakin, Abigail Schiller, Nirit Egoz-Matia, Eliezer Masliah, Daniel Segal, Ehud Gazit
J Biol Chem 2013 May;
PMID: Object id #145523637226 [PubMed - as supplied by publisher]

Striatal Dopamine Transporter Binding Does Not Correlate with Clinical Severity in Dementia with Lewy Bodies.
Morten Ziebell, Birgitte B Andersen, Lars H Pinborg, Gitte M Knudsen, Jette Stokholm, Gerda Thomsen, Merete Karlsborg, Peter Høgh, Mette Louise Mørk, Steen G Hasselbalch
J Nucl Med 2013 May;
PMID: Object id #147523637201 [PubMed - as supplied by publisher]

Treadmill exercise elevates striatal dopamine D2 receptor binding potential in patients with early Parkinson's disease.
Beth E Fisher, Quanzheng Li, Angelo Nacca, George J Salem, Jooeun Song, Jeanine Yip, Jennifer S Hui, Michael W Jakowec, Giselle M Petzinger
Neuroreport 2013 Apr;
PMID: Object id #150623636255 [PubMed - as supplied by publisher]

Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis.
David Freeman, Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M Burrage, Stacey Sudholt, Ajay Rana, Christopher O'Connor, Christopher M Wiethoff, Edward M Campbell
PLoS One 2013 ; 8(4):e62143
PMID: Object id #153723634225 [PubMed - as supplied by publisher]

Infectious particles, stress, and induced prion amyloids: A unifying perspective.
Laura Manuelidis
Virulence 2013 Apr; 4(5)
PMID: Object id #162023633671 [PubMed - as supplied by publisher]

Reduced ?-synuclein levels in cerebrospinal fluid in Parkinson's disease are unrelated to clinical and imaging measures of disease severity.
K D van Dijk, M Bidinosti, A Weiss, P Raijmakers, H W Berendse, W D J van de Berg
Eur J Neurol 2013 Apr;
PMID: Object id #164023631635 [PubMed - as supplied by publisher]

Cortical information flow in Parkinson's disease: a composite network/field model.
Cliff C Kerr, Sacha J Van Albada, Samuel A Neymotin, George L Chadderdon, P A Robinson, William W Lytton
Front Comput Neurosci 2013 ; 7:39
PMID: Object id #166823630492 [PubMed - as supplied by publisher]

Fall Risk and Fracture. Falls and fractures in patients with neurological disorders].
Akira Tamaoka
Clin Calcium 2013 May; 23(5):679-85
PMID: Object id #169423628680 [PubMed - as supplied by publisher]

Cell clocks and neuronal networks: neuron ticking and synchronization in aging and aging - related neurodegenerative disease.
M Bonaconsa, V Colavito, F Pifferi, F Aujard, E Schenker, S Dix, G Grassi-Zucconi, M Bentivoglio, G Bertini
Curr Alzheimer Res 2013 Apr;
PMID: Object id #174523627753 [PubMed - as supplied by publisher]

TOM40 Mediates Mitochondrial Dysfunction Induced by ?-Synuclein Accumulation in Parkinson's Disease.
Andreas Bender, Paula Desplats, Brian Spencer, Edward Rockenstein, Anthony Adame, Matthias Elstner, Christoph Laub, Sarina Mueller, Andrew O Koob, Michael Mante, Emily Pham, Thomas Klopstock, Eliezer Masliah
PLoS One 2013 ; 8(4):e62277
PMID: Object id #177423626796 [PubMed - as supplied by publisher]

Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection.
Jean-François Trempe, Edward A Fon
Front Neurol 2013 ; 4:38
PMID: Object id #195423626584 [PubMed - as supplied by publisher]

PACAP Protects Against Salsolinol-Induced Toxicity in Dopaminergic SH-SY5Y Cells: Implication for Parkinson's Disease.
Dwayne Brown, Andrea Tamas, Dora Reglödi, Yousef Tizabi
J Mol Neurosci 2013 Apr;
PMID: Object id #198323625270 [PubMed - as supplied by publisher]

Development and Screening of Contrast Agents for In Vivo Imaging of Parkinson's Disease.
Krista L Neal, Naomi B Shakerdge, Steven S Hou, William E Klunk, Chester A Mathis, Evgueni E Nesterov, Timothy M Swager, Pamela J McLean, Brian J Bacskai
Mol Imaging Biol 2013 Apr;
PMID: Object id #204823624948 [PubMed - as supplied by publisher]

Decision making: from neuroscience to psychiatry.
Daeyeol Lee
Neuron 2013 Apr; 78(2):233-48
PMID: Object id #211523622061 [PubMed - as supplied by publisher]

Formulation and characterization of nanostructured lipid carrier of ubiquinone (Coenzyme Q10).
Basavaraj K Nanjwade, Vikrant T Kadam, F V Manvi
J Biomed Nanotechnol 2013 Mar; 9(3):450-60
PMID: Object id #214923621001 [PubMed - as supplied by publisher]

Functional paraoxonase 1 variants modify the risk of Parkinson's disease due to organophosphate exposure.
Pei-Chen Lee, Shannon L Rhodes, Janet S Sinsheimer, Jeff Bronstein, Beate Ritz
Environ Int 2013 Jun; 56:42-7
PMID: Object id #257023602893 [PubMed - as supplied by publisher]

PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Yun Chen, Gerald W Dorn
Science 2013 Apr; 340(6131):471-5
PMID: Object id #216223620051 [PubMed - as supplied by publisher]

The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration.
Maddalena Costanzo, Chiara Zurzolo
Biochem J 2013 May; 452(1):1-17
PMID: Object id #232123614720 [PubMed - as supplied by publisher]

Elevated TRAF2/6 expression in Parkinson's disease is caused by the loss of Parkin E3 ligase activity.
Ji-Yun Chung, Hee Ra Park, Su-Jin Lee, Sun-Hye Lee, Jin Sik Kim, Youn-Sang Jung, Sang Hyun Hwang, Nam-Chul Ha, Won-Gi Seol, Jaewon Lee, Bum-Joon Park
Lab Invest 2013 Apr;
PMID: Object id #236523608757 [PubMed - as supplied by publisher]

Betaine Protects Against Rotenone-Induced Neurotoxicity in PC12 Cells.
A-Rang Im, Young-Hwa Kim, Md Romij Uddin, Sungwook Chae, Hye Won Lee, Yun Hee Kim, Yeong Shik Kim, Mi-Young Lee
Cell Mol Neurobiol 2013 Apr;
PMID: Object id #244723605682 [PubMed - as supplied by publisher]

The Analog of Ginkgo biloba Extract 761 is a Protective Factor of Cognitive Impairment Induced by Chronic Fluorosis.
Caiyi Zhang, Chao Ren, Hao Chen, Runlu Geng, Hongbin Fan, Houfeng Zhao, Ketai Guo, Deqin Geng
Biol Trace Elem Res 2013 Apr;
PMID: Object id #185923605048 [PubMed - as supplied by publisher]

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.
Jens Wagner, Sergey Ryazanov, Andrei Leonov, Johannes Levin, Song Shi, Felix Schmidt, Catharina Prix, Francisco Pan-Montojo, Uwe Bertsch, Gerda Mitteregger-Kretzschmar, Markus Geissen, Martin Eiden, Fabienne Leidel, Thomas Hirschberger, Andreas A Deeg, Julian J Krauth, Wolfgang Zinth, Paul Tavan, Jens Pilger, Markus Zweckstetter, Tobias Frank, Mathias Bähr, Jochen H Weishaupt, Manfred Uhr, Henning Urlaub, Ulrike Teichmann, Matthias Samwer, Kai Bötzel, Martin Groschup, Hans Kretzschmar, Christian Griesinger, Armin Giese
Acta Neuropathol 2013 Apr;
PMID: Object id #181923604588 [PubMed - as supplied by publisher]

?-Synuclein in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment.
Ane Korff, Changqin Liu, Carmen Ginghina, Min Shi, Jing Zhang
J Alzheimers Dis 2013 Apr;
PMID: Object id #248723603399 [PubMed - as supplied by publisher]

The Parkinson's disease associated LRRK2 mutation R1441G inhibits neuronal differentiation of neural stem cells.
Lamia'a Bahnassawy, Sarah Nicklas, Thomas Palm, Ingeborg Menzl, Fabian Birzele, Frank Gillardon, Jens Christian Schwamborn
Stem Cells Dev 2013 Apr;
PMID: Object id #305023600457 [PubMed - as supplied by publisher]