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Effect of subthalamic nucleus deep brain stimulation on dual-task cognitive and motor performance in isolated dystonia.
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J Neurol Neurosurg Psychiatry 2014 Jul;
Authors: Kelly A Mills, Leslie C Markun, Marta San Luciano, Rami Rizk, I Elaine Allen, Caroline A Racine, Philip A Starr, Jay L Alberts, Jill L Ostrem
Subthalamic nucleus (STN) deep brain stimulation (DBS) can improve motor complications of Parkinson's disease (PD) but may worsen specific cognitive functions. The effect of STN DBS on cognitive function in dystonia patients is less clear. Previous reports indicate that bilateral STN stimulation in patients with PD amplifies the decrement in cognitive-motor dual-task performance seen when moving from a single-task to dual-task paradigm. We aimed to determine if the effect of bilateral STN DBS on dual-task performance in isolated patients with dystonia, who have less cognitive impairment and no dementia, is similar to that seen in PD.
PMID: 25012202 [PubMed - as supplied by publisher]