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Can we predict who is at risk of facing cognitive issues in PD and address them earlier? These are the questions being pursued by Dr. Goldman of the PDF Research Center at Rush University Medical Center.

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Coordinated reset neuromodulation for Parkinson's disease: Proof-of-concept study.

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Mov Disord 2014 Jun;

Authors: Ilya Adamchic, Christian Hauptmann, Utako Brigit Barnikol, Norbert Pawelczyk, Oleksandr Popovych, Thomas Theo Barnikol, Alexander Silchenko, Jens Volkmann, GŁnter Deuschl, Wassilios G Meissner, Mohammad Maarouf, Volker Sturm, Hans-Joachim Freund, Peter Alexander Tass

The discovery of abnormal synchronization of neuronal activity in the basal ganglia in Parkinson's disease (PD) has prompted the development of novel neuromodulation paradigms. Coordinated reset neuromodulation intends to specifically counteract excessive synchronization and to induce cumulative unlearning of pathological synaptic connectivity and neuronal synchrony.

PMID: 24976001 [PubMed - as supplied by publisher]

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