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Featured Research

Can we predict who is at risk of facing cognitive issues in PD and address them earlier? These are the questions being pursued by Dr. Goldman of the PDF Research Center at Rush University Medical Center.

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Treatments/Pipeline

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.

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The Rationale Driving the Evolution of Deep Brain Stimulation to Constant-Current Devices.
Jeff M Bronstein, Michele Tagliati, Cameron McIntyre, Robert Chen, Tyler Cheung, Eric L Hargreaves, Zvi Israel, Michael Moffitt, Erwin B Montgomery, Paul Stypulkowski, Jay Shils, Timothy Denison, Jerrold Vitek, Jens Volkman, Jeffrey Wertheimer, Michael S Okun
Neuromodulation 2014 Aug;
PMID: 25171762 [PubMed - as supplied by publisher]


Clinical Implications of Local Field Potentials for Understanding and Treating Movement Disorders.
John A Thompson, David Lanctin, Nuri Firat Ince, Aviva Abosch
Stereotact Funct Neurosurg 2014 Aug; 92(4):251-263
PMID: 25170784 [PubMed - as supplied by publisher]


Neurostimulation for traumatic brain injury.
Samuel S Shin, C Edward Dixon, David O Okonkwo, R Mark Richardson
J Neurosurg 2014 Aug; :1-13
PMID: 25170668 [PubMed - as supplied by publisher]


Polyneuropathy associated with duodenal infusion of levodopa in Parkinson's disease: features, pathogenesis and management.
Antonino Uncini, Roberto Eleopra, Marco Onofrj
J Neurol Neurosurg Psychiatry 2014 Aug;
PMID: 25168395 [PubMed - as supplied by publisher]


Emerging drugs for levodopa-induced dyskinesia.
Amaal Al Dakheel, Isabelle Beaulieu-Boire, Susan H Fox
Expert Opin Emerg Drugs 2014 Sep; 19(3):415-29
PMID: 25146568 [PubMed - as supplied by publisher]


Human adipose-Derived Mesenchymal Stem Cells Improve Motor Functions and are Neuroprotective in the 6-Hydroxydopamine-Rat Model for Parkinson's Disease when Cultured in Monolayer Cultures but Suppress Hippocampal Neurogenesis and Hippocampal Memory Function when Cultured in Spheroids.
Jürgen Berg, Manfred Roch, Jennifer Altschüler, Christine Winter, Anne Schwerk, Andreas Kurtz, Barbara Steiner
Stem Cell Rev 2014 Aug;
PMID: 25120226 [PubMed - as supplied by publisher]


Lack of depotentiation at basal ganglia output neurons in PD patients with levodopa-induced dyskinesia.
I A Prescott, L D Liu, J O Dostrovsky, M Hodaie, A M Lozano, W D Hutchison
Neurobiol Dis 2014 Aug; 71C:24-33
PMID: 25116960 [PubMed - as supplied by publisher]


Phenotypic variability of PINK1 expression: 12 Years' clinical follow-up of two Italian families.
Lucia Ricciardi, Simona Petrucci, Arianna Guidubaldi, Tamara Ialongo, Laura Serra, Alessandro Ferraris, Barbara Spanò, Marco Bozzali, Enza Maria Valente, Anna Rita Bentivoglio
Mov Disord 2014 Aug;
PMID: 25164310 [PubMed - as supplied by publisher]


The molecular mechanism of intestinal levodopa absorption and its possible implications for the treatment of Parkinson's disease.
Simone M R Camargo, Raphael N Vuille-Dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze, François Verrey
J Pharmacol Exp Ther 2014 Oct; 351(1):114-23
PMID: 25073474 [PubMed - as supplied by publisher]


Engineering the Next Generation of Clinical Deep Brain Stimulation Technology.
Cameron C McIntyre, Ashutosh Chaturvedi, Reuben R Shamir, Scott F Lempka
Brain Stimul 2014 Jul;
PMID: 25161150 [PubMed - as supplied by publisher]


Modulation of the Cerebello-thalamo-cortical Network in Thalamic Deep Brain Stimulation for Tremor: A Diffusion Tensor Imaging Study.
Volker Arnd Coenen, Niels Allert, Sebastian Paus, Martin Kronenbürger, Horst Urbach, Burkhard Mädler
Neurosurgery 2014 Aug;
PMID: 25161000 [PubMed - as supplied by publisher]


Angiotensin type 1 receptor blockage reduces L-dopa-induced dyskinesia in the 6-OHDA model of Parkinson's disease. Involvement of Vascular Endothelial Growth Factor and interleukin-1?
Ana Muñoz, Pablo Garrido-Gil, Antonio Dominguez-Meijide, Jose L Labandeira-Garcia
Exp Neurol 2014 Aug;
PMID: 25160895 [PubMed - as supplied by publisher]


The H3 receptor agonist immepip does not affect L-dopa-induced abnormal involuntary movements in 6-OHDA-lesioned rats.
Maria Papathanou, Peter Jenner, Mahmoud Iravani, Michael Jackson, Kim Stockwell, Isabel Strang, Bai-Yun Zeng, Andrew C McCreary, Sarah Rose
Eur J Pharmacol 2014 Aug;
PMID: 25160743 [PubMed - as supplied by publisher]


Treatment of aging vocal folds: surgical approaches.
Yutomo Seino, Jacqui E Allen
Curr Opin Otolaryngol Head Neck Surg 2014 Aug;
PMID: 25160615 [PubMed - as supplied by publisher]


Comparing neuroprotective effects of CDNF-expressing bone marrow derived mesenchymal stem cells via differing routes of administration utilizing an in vivo model of Parkinson's disease.
Mei Jiaming, Chaoshi Niu
Neurol Sci 2014 Aug;
PMID: 25159816 [PubMed - as supplied by publisher]


Gene Therapy for the Nervous System: Challenges and New Strategies.
Casey A Maguire, Servio H Ramirez, Steven F Merkel, Miguel Sena-Esteves, Xandra O Breakefield
Neurotherapeutics 2014 Aug;
PMID: 25159276 [PubMed - as supplied by publisher]


Neuroprotective and neurotrophic effects of Apigenin and Luteolin in MPTP induced parkinsonism in mice.
Sachin P Patil, Pankaj D Jain, Jayant S Sancheti, Priya J Ghumatkar, Rufi Tambe, Sadhana Sathaye
Neuropharmacology 2014 Jul; 86C:192-202
PMID: 25087727 [PubMed - as supplied by publisher]


Mixed effects of deep brain stimulation on depressive symptomatology in Parkinson's disease: a review of randomized clinical trials.
N Simay Gökbayrak, Irene Piryatinsky, Rebecca A Gavett, Omar J Ahmed
Front Neurol 2014 ; 5:154
PMID: 25157240 [PubMed - as supplied by publisher]


Effect of Advancing Age on Outcomes of Deep Brain Stimulation for Parkinson Disease.
Michael R DeLong, Kevin T Huang, John Gallis, Yuliya Lokhnygina, Beth Parente, Patrick Hickey, Dennis A Turner, Shivanand P Lad
JAMA Neurol 2014 Aug;
PMID: 25155481 [PubMed - as supplied by publisher]


Endothelial dysfunction and hyperhomocysteinemia in Parkinson's disease: Flow-mediated dilation study.
Jung Han Yoon, Jin Soo Lee, Seok Woo Yong, Ji Man Hong, Phil Hyu Lee
Mov Disord 2014 Aug;
PMID: 25154960 [PubMed - as supplied by publisher]


SOX9 as a Predictor for Neurogenesis Potentiality of Amniotic Fluid Stem Cells.
Pei-Cih Wei, Angel Chao, Hsiu-Huei Peng, An-Shine Chao, Yao-Lung Chang, Shuenn-Dyh Chang, Hsin-Shih Wang, Yu-Jen Chang, Ming-Song Tsai, Martin Sieber, Hua-Chien Chen, Shu-Jen Chen, Yun-Shien Lee, Shiaw-Min Hwang, Tzu-Hao Wang
Stem Cells Transl Med 2014 Aug;
PMID: 25154783 [PubMed - as supplied by publisher]


Parkinson disease: Can a new trial end controversy over when to use levodopa?
Olivier Rascol
Nat Rev Neurol 2014 Aug;
PMID: 25134709 [PubMed - as supplied by publisher]


Time up and go task performance improves after transcranial direct current stimulation in patient affected by Parkinson's disease.
Rosa Manenti, Michela Brambilla, Sandra Rosini, Italo Orizio, Clarissa Ferrari, Barbara Borroni, Maria Cotelli
Neurosci Lett 2014 Aug; 580C:74-77
PMID: 25107738 [PubMed - as supplied by publisher]


Ceftriaxone mediated rescue of nigral oxidative damage and motor deficits in MPTP model of Parkinson's disease in rats.
Rohit Bisht, Baninder Kaur, Hitu Gupta, Atish Prakash
Neurotoxicology 2014 Jun; 44C:71-79
PMID: 25053526 [PubMed - as supplied by publisher]


Diffusion tensor imaging differentiates vascular parkinsonism from parkinsonian syndromes of degenerative origin in elderly subjects.
Jérémy Deverdun, Sophie Menjot de Champfleur, Simon Cabello-Aguilar, Florence Maury, François Molino, Mahmoud Charif, Nicolas Leboucq, Xavier Ayrignac, Pierre Labauge, Alain Bonafe, Giovanni Castelnovo, Emmanuelle Le Bars, Christian Geny, Nicolas Menjot de Champfleur
Eur J Radiol 2014 Jul;
PMID: 25154005 [PubMed - as supplied by publisher]


Advances in the application of gene therapy for Parkinson's disease with adeno-associated virus].
Yang Chen, Ying-Hui Lü, Zhao-Fa Li
Yao Xue Xue Bao 2014 May; 49(5):576-81
PMID: 25151724 [PubMed - as supplied by publisher]


Stimulation of the subthalamic area modulating movement and behavior.
L Ricciardi, L Morgante, A Epifanio, M Zibetti, M Lanotte, L Lopiano, F Morgante
Parkinsonism Relat Disord 2014 Aug;
PMID: 25150771 [PubMed - as supplied by publisher]


Directional steering: A novel approach to deep brain stimulation.
M Fiorella Contarino, Lo J Bour, Rens Verhagen, Marcel A J Lourens, Rob M A de Bie, Pepijn van den Munckhof, P R Schuurman
Neurology 2014 Aug;
PMID: 25150285 [PubMed - as supplied by publisher]


Proceedings: Cell Therapies for Parkinson's Disease From Discovery to Clinic.
Rosa Canet-Aviles, Geoffrey P Lomax, Ellen G Feigal, Catherine Priest
Stem Cells Transl Med 2014 Aug;
PMID: 25150264 [PubMed - as supplied by publisher]


Sox6 and otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons.
Lia Panman, Maria Papathanou, Ariadna Laguna, Tony Oosterveen, Nikolaos Volakakis, Dario Acampora, Idha Kurtsdotter, Takashi Yoshitake, Jan Kehr, Eliza Joodmardi, Jonas Muhr, Antonio Simeone, Johan Ericson, Thomas Perlmann
Cell Rep 2014 Aug; 8(4):1018-25
PMID: 25127144 [PubMed - as supplied by publisher]


A new HILIC-MS/MS method for the simultaneous analysis of carbidopa, levodopa, and its metabolites in human plasma.
Raquel de Oliveira Vilhena, Flávia Lada Degaut Pontes, Breno Maurício Marson, Rômulo Pereira Ribeiro, Katherine Athayde Teixeira de Carvalho, Marco André Cardoso, Roberto Pontarolo
J Chromatogr B Analyt Technol Biomed Life Sci 2014 Sep; 967:41-9
PMID: 25063927 [PubMed - as supplied by publisher]


The degeneration and replacement of dopamine cells in Parkinson's disease: the role of aging.
Manuel Rodriguez, Ingrid Morales, Clara Rodriguez-Sabate, Alberto Sanchez, Rafael Castro, Jose Miguel Brito, Magdalena Sabate
Front Neuroanat 2014 ; 8:80
PMID: 25147507 [PubMed - as supplied by publisher]


IPX066 , a mixed immediate/sustained-release levodopa preparation for Parkinson's disease.
William Ondo
Expert Opin Pharmacother 2014 Aug; :1-5
PMID: 25146967 [PubMed - as supplied by publisher]


Induced Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Neurodegenerative Diseases.
Lei Cao, Lan Tan, Teng Jiang, Xi-Chen Zhu, Jin-Tai Yu
Mol Neurobiol 2014 Aug;
PMID: 25146848 [PubMed - as supplied by publisher]


Designer's microglia with novel delivery system in neurodegenerative diseases.
Abdul Mannan Baig
Med Hypotheses 2014 Aug;
PMID: 25146247 [PubMed - as supplied by publisher]


Frequency matters: beta-band subthalamic nucleus deep-brain stimulation induces Parkinsonian-like blink abnormalities in normal rats.
Jaime Kaminer, Pratibha Thakur, Craig Evinger
Eur J Neurosci 2014 Aug;
PMID: 25146113 [PubMed - as supplied by publisher]


Rotigotine transdermal system: developing continuous dopaminergic delivery to treat Parkinson's disease and restless legs syndrome.
Arturo Benitez, Heather Edens, Jesse Fishman, Kimberly Moran, Mahnaz Asgharnejad
Ann N Y Acad Sci 2014 Aug;
PMID: 25145951 [PubMed - as supplied by publisher]


Therapeutics with SPION-labeled stem cells for the main diseases related to brain aging: a systematic review.
Larissa T Alvarim, Leopoldo P Nucci, Javier B Mamani, Luciana C Marti, Marina F Aguiar, Helio R Silva, Gisele S Silva, Mariana P Nucci-da-Silva, Elaine A DelBel, Lionel F Gamarra
Int J Nanomedicine 2014 ; 9:3749-3770
PMID: 25143726 [PubMed - as supplied by publisher]


Parkinson's disease pharmacogenomics: new findings and perspectives.
Artur F Schumacher-Schuh, Carlos Rm Rieder, Mara H Hutz
Pharmacogenomics 2014 Jun; 15(9):1253-71
PMID: 25141900 [PubMed - as supplied by publisher]


Pharmacological Treatments Inhibiting Levodopa-Induced Dyskinesias in MPTP-Lesioned Monkeys: Brain Glutamate Biochemical Correlates.
Nicolas Morin, Thérèse Di Paolo
Front Neurol 2014 ; 5:144
PMID: 25140165 [PubMed - as supplied by publisher]


Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine.
Janaína K Barbiero, Ronise M Santiago, Daniele Suzete Persike, Maria José da Silva Fernandes, Fernanda S Tonin, Claudio da Cunha, Suelen Boschen, Marcelo M S Lima, Maria A B F Vital
Behav Brain Res 2014 Aug;
PMID: 25127682 [PubMed - as supplied by publisher]


A randomised clinical trial to evaluate the effects of Plantago ovata husk in Parkinson patients: changes in levodopa pharmacokinetics and biochemical parameters.
M Nelida Fernandez-Martinez, Luis Hernandez-Echevarria, Matilde Sierra-Vega, M Jose Diez-Liebana, Angela Calle-Pardo, Demetrio Carriedo-Ule, Ana M Sahagún-Prieto, Anna Anguera-Vila, Juan Jose Garcia-Vieitez
BMC Complement Altern Med 2014 ; 14:296
PMID: 25112783 [PubMed - as supplied by publisher]


Opposite Effects of Bone Marrow-Derived Cells Transplantation in MPTP-rat Model of Parkinson's Disease: A Comparison Study of Mononuclear and Mesenchymal Stem Cells.
Caroline Santos Capitelli, Carolina Salomão Lopes, Angélica Cristina Alves, Janaína Barbiero, Lucas Felipe Oliveira, Valdo José Dias da Silva, Maria Aparecida Barbato Frazão Vital
Int J Med Sci 2014 ; 11(10):1049-64
PMID: 25136260 [PubMed - as supplied by publisher]


In vivo gastric detection of ?-synuclein inclusions in Parkinson's disease.
Alvaro Sánchez-Ferro, Alberto Rábano, María José Catalán, Fernando Canga Rodríguez-Valcárcel, Servando Fernández Díez, Jaime Herreros-Rodríguez, Elvira García-Cobos, Marina Mata Alvarez-Santullano, Lydia López-Manzanares, Antonio J Mosqueira, Lydia Vela Desojo, Juan José López-Lozano, Eva López-Valdés, Rafael Sánchez-Sánchez, José Antonio Molina-Arjona
Mov Disord 2014 Aug;
PMID: 25113060 [PubMed - as supplied by publisher]


Dopamine receptor D3 deficiency results in chronic depression and anxiety.
Rodrigo Moraga-Amaro, Hugo Gonzalez, Rodrigo Pacheco, Jimmy Stehberg
Behav Brain Res 2014 Aug;
PMID: 25110304 [PubMed - as supplied by publisher]


Quercetin Glycosides Induced Neuroprotection by Changes in the Gene Expression in a Cellular Model of Parkinson's Disease.
Kasthuri Bai Magalingam, Ammu Radhakrishnan, Premdass Ramdas, Nagaraja Haleagrahara
J Mol Neurosci 2014 Aug;
PMID: 25129099 [PubMed - as supplied by publisher]


Does lesioning surgery have a role in the management of multietiological tremor in the era of Deep Brain Stimulation?
Srinivas Dwarakanath, Abu Zafar, Ravi Yadav, A Arivazhagan, M Netravathi, S Sampath, Pramod Kumar Pal
Clin Neurol Neurosurg 2014 Jul; 125C:131-136
PMID: 25128653 [PubMed - as supplied by publisher]


Frontiers in therapeutic development of allopregnanolone for Alzheimer's disease and other neurological disorders.
Ronald W Irwin, Christine M Solinsky, Roberta Diaz Brinton
Front Cell Neurosci 2014 ; 8:203
PMID: 25126056 [PubMed - as supplied by publisher]


Does early verbal fluency decline after STN implantation predict long-term cognitive outcome after STN-DBS in Parkinson's disease?
Alaina Borden, David Wallon, Romain Lefaucheur, Stéphane Derrey, Damien Fetter, Marc Verin, David Maltête
J Neurol Sci 2014 Aug;
PMID: 25125047 [PubMed - as supplied by publisher]


Stimulation of the subthalamic nucleus engages the cerebellum for motor function in parkinsonian rats.
Alexander C Sutton, Katherine A O'Connor, Julie G Pilitsis, Damian S Shin
Brain Struct Funct 2014 Aug;
PMID: 25124274 [PubMed - as supplied by publisher]


Reversible Pisa syndrome associated to subdural haematoma: case-report.
Pasquale Marchione, Aldo Spallone, Marcella Valente, Cristiano Giannone, Floriana De Angelis, Giuseppe Meco
BMC Neurol 2014 Aug; 14(1):149
PMID: 25123109 [PubMed - as supplied by publisher]


Deep brain stimulation abolishes slowing of reactions to unlikely stimuli.
Chrystalina A Antoniades, Rafal Bogacz, Christopher Kennard, James J FitzGerald, Tipu Aziz, Alexander L Green
J Neurosci 2014 Aug; 34(33):10844-52
PMID: 25122887 [PubMed - as supplied by publisher]


Deep brain stimulation for tremor associated with underlying ataxia syndromes: a case series and discussion of issues.
Genko Oyama, Amanda Thompson, Kelly D Foote, Natlada Limotai, Muhammad Abd-El-Barr, Nicholas Maling, Irene A Malaty, Ramon L Rodriguez, Sankarasubramoney H Subramony, Testuo Ashizawa, Michael S Okun
Tremor Other Hyperkinet Mov (N Y) 2014 ; 4:228
PMID: 25120941 [PubMed - as supplied by publisher]


Effects of combined MAO-B inhibitors and levodopa vs. monotherapy in Parkinson's disease.
Rakhee Krishna, Manal Ali, Ahmed A Moustafa
Front Aging Neurosci 2014 ; 6:180
PMID: 25120478 [PubMed - as supplied by publisher]


Regulation and targeting of enzymes mediating Parkinson's disease pathogenesis: focus on Parkinson's disease kinases, GTPases, and ATPases.
Jean-Marc Taymans, Veerle Baekelandt, Kirsten Harvey
Front Mol Neurosci 2014 ; 7:71
PMID: 25120428 [PubMed - as supplied by publisher]


Neuroprotective effect of rotigotine against complex I inhibitors, MPP+ and rotenone, in primary mesencephalic cell culture.
K Radad, D Scheller, W-D Rausch, H Reichmann, G Gille
Folia Neuropathol 2014 ; 52(2):179-86
PMID: 25118903 [PubMed - as supplied by publisher]


The Effect of Lentivirus-Mediated PSPN Genetic Engineering Bone Marrow Mesenchymal Stem Cells on Parkinson's Disease Rat Model.
Xiaofeng Yin, Huamin Xu, Yunxia Jiang, Wenshuai Deng, Zeyu Wu, Hengwei Xiang, Peng Sun, Junxia Xie
PLoS One 2014 ; 9(8):e105118
PMID: 25118697 [PubMed - as supplied by publisher]


Eye movements in ephedrone-induced parkinsonism.
Cecilia Bonnet, Jan Rusz, Marika Megrelishvili, Tomá? Sieger, Olga Matou?ková, Michael Okujava, Hana Bro?ová, Tomá? Nikolai, Jaromír Hanu?ka, Mariam Kapianidze, Nina Mikeladze, Nazi Botchorishvili, Irine Khatiashvili, Marina Janelidze, Tereza Serranová, Ond?ej Fiala, Jan Roth, Jonas Bergquist, Robert Jech, Sophie Rivaud-Péchoux, Bertrand Gaymard, Ev?en R??i?ka
PLoS One 2014 ; 9(8):e104784
PMID: 25117825 [PubMed - as supplied by publisher]


The efficacy and safety of pramipexole ER versus IR in Chinese patients with Parkinson's disease: a randomized, double-blind, double-dummy, parallel-group study.
Ying Wang, Shenggang Sun, Suiqiang Zhu, Chunfeng Liu, Yiming Liu, Qing Di, Huifang Shang, Yan Ren, Changhong Lu, Mark Forrest Gordon, Nolwenn Juhel, Shengdi Chen
Transl Neurodegener 2014 ; 3:11
PMID: 25114789 [PubMed - as supplied by publisher]


Continuous dopaminergic stimulation (CDS)-based treatment in Parkinson's disease patients with motor complications: A systematic review and meta-analysis.
Cheng-Long Xie, Wen-Wen Wang, Su-Fang Zhang, Jing Gan, Zhen-Guo Liu
Sci Rep 2014 ; 4:6027
PMID: 25113733 [PubMed - as supplied by publisher]


Comparison of magnetic resonance imaging sequences for depicting the subthalamic nucleus for deep brain stimulation.
Hiroshi Nagahama, Kengo Suzuki, Takaharu Shonai, Kazuki Aratani, Yuuki Sakurai, Manami Nakamura, Motomichi Sakata
Radiol Phys Technol 2014 Aug;
PMID: 25113409 [PubMed - as supplied by publisher]


The appropriate use of neurostimulation: stimulation of the intracranial and extracranial space and head for chronic pain.
Timothy R Deer, Nagy Mekhail, Erika Petersen, Elliot Krames, Peter Staats, Jason Pope, Youssef Saweris, Shivanand P Lad, Sudhir Diwan, Steven Falowski, Claudio Feler, Konstantin Slavin, Samer Narouze, Lotfi Merabet, Asokumar Buvanendran, Felipe Fregni, Joshua Wellington, Robert M Levy
Neuromodulation 2014 Aug; 17(6):551-70
PMID: 25112890 [PubMed - as supplied by publisher]


Adult Hippocampal Neurogenesis in Parkinson's Disease: Impact on Neuronal Survival and Plasticity.
Martin Regensburger, Iryna Prots, Beate Winner
Neural Plast 2014 ; 2014:454696
PMID: 25110593 [PubMed - as supplied by publisher]


Survival and engraftment of dopaminergic neurons manufactured by a Good Manufacturing Practice-compatible process.
Jun Peng, Qiuyue Liu, Mahendra S Rao, Xianmin Zeng
Cytotherapy 2014 Sep; 16(9):1305-12
PMID: 25065637 [PubMed - as supplied by publisher]


Catechol-O-methyltransferase Val158Met polymorphism: Modulation of wearing-off susceptibility in a Chinese cohort of Parkinson's disease.
Hui Wu, Fangyi Dong, Ying Wang, Qin Xiao, Qiong Yang, Jing Zhao, Thomas J Quinn, Sheng-di Chen, Jun Liu
Parkinsonism Relat Disord 2014 Jul;
PMID: 25108642 [PubMed - as supplied by publisher]


Dopaminergic modulation of emotional conflict in Parkinson's disease.
Vanessa Fleury, Emilie Cousin, Virginie Czernecki, Emmanuelle Schmitt, Eugénie Lhommée, Antoine Poncet, Valérie Fraix, Irène Troprès, Pierre Pollak, Alexandre Krainik, Paul Krack
Front Aging Neurosci 2014 ; 6:164
PMID: 25100991 [PubMed - as supplied by publisher]


Origins and suppression of oscillations in a computational model of Parkinson's disease.
Abbey B Holt, Theoden I Netoff
J Comput Neurosci 2014 Aug;
PMID: 25099916 [PubMed - as supplied by publisher]


Effect of Subthalamic Nuclei Electrical Stimulation in the Treatment of Parkinson's Disease.
Yingqun Tao, Guobiao Liang
Cell Biochem Biophys 2014 Aug;
PMID: 25099644 [PubMed - as supplied by publisher]


Anatomical Targets Associated with Abrupt versus Gradual Washout of Subthalamic Deep Brain Stimulation Effects on Bradykinesia.
Scott E Cooper, Klaus G Driesslein, Angela M Noecker, Cameron C McIntyre, Andre M Machado, Christopher R Butson
PLoS One 2014 ; 9(8):e99663
PMID: 25098453 [PubMed - as supplied by publisher]


Efficacy of Adenosine A2A Receptor Antagonist Istradefylline as Augmentation for Parkinson's Disease: A Meta-analysis of Randomized Controlled Trials.
Yingqun Tao, Guobiao Liang
Cell Biochem Biophys 2014 Aug;
PMID: 25096504 [PubMed - as supplied by publisher]


Clinical insights into use of apomorphine in Parkinson's disease: tools for clinicians.
Tove Henriksen
Neurodegener Dis Manag 2014 Jun; 4(3):271-82
PMID: 25095821 [PubMed - as supplied by publisher]


Beta Band Frequency Peaks inside the Subthalamic Nucleus as a Biomarker for Motor Improvement after Deep Brain Stimulation in Parkinson's Disease.
Konstantinos P Michmizos, Polytimi Frangou, Pantelis Stathis, Damianos Sakas, Konstantina S Nikita
IEEE J Biomed Health Inform 2014 Jul;
PMID: 25095273 [PubMed - as supplied by publisher]


Management of L-dopa overdose in the competitive inhibition state.
Marty Hinz, Alvin Stein, Ted Cole
Drug Healthc Patient Saf 2014 ; 6:93-9
PMID: 25092997 [PubMed - as supplied by publisher]


Late stages of hematopoiesis and B cell lymphopoiesis are regulated by ?-synuclein, a key player in Parkinson's disease.
Wenbin Xiao, Afshin Shameli, Clifford V Harding, Howard J Meyerson, Robert W Maitta
Immunobiology 2014 Jul;
PMID: 25092570 [PubMed - as supplied by publisher]


Effects of Five Ayurvedic Herbs on Locomotor Behaviour in a Drosophila melanogaster Parkinson's Disease Model.
R L M Jansen, B Brogan, A J Whitworth, E J Okello
Phytother Res 2014 Aug;
PMID: 25091506 [PubMed - as supplied by publisher]


REM sleep behavior disorder: Association with motor complications and impulse control disorders in Parkinson's disease.
Young Eun Kim, Beom S Jeon, Hui-Jun Yang, Gwanhee Ehm, Ji Young Yun, Han-Joon Kim, Jong-Min Kim
Parkinsonism Relat Disord 2014 Apr;
PMID: 25085747 [PubMed - as supplied by publisher]


Subthalamic deep brain stimulation improves auditory sensory gating deficit in Parkinson's disease.
A Gulberti, W Hamel, C Buhmann, K Boelmans, S Zittel, C Gerloff, M Westphal, A K Engel, T R Schneider, C K E Moll
Clin Neurophysiol 2014 Jul;
PMID: 25085452 [PubMed - as supplied by publisher]


Functional correlates of exaggerated oscillatory activity in basal ganglia output in hemiparkinsonian rats.
Elena Brazhnik, Nikolay Novikov, Alex J McCoy, Ana V Cruz, Judith R Walters
Exp Neurol 2014 Jul;
PMID: 25084518 [PubMed - as supplied by publisher]


Mapping the conformational space accessible to catechol-O-methyltransferase.
Andreas Ehler, Jörg Benz, Daniel Schlatter, Markus G Rudolph
Acta Crystallogr D Biol Crystallogr 2014 Aug; 70(Pt 8):2163-74
PMID: 25084335 [PubMed - as supplied by publisher]


Mitochondrial Oxidative Phosphorylation Transcriptome Alterations in Human Amyotrophic Lateral Sclerosis Spinal Cord and Blood.
Amy C Ladd, Paula M Keeney, Maria M Govind, James P Bennett
Neuromolecular Med 2014 Aug;
PMID: 25081190 [PubMed - as supplied by publisher]


Controlling Parkinson's disease with adaptive deep brain stimulation.
Simon Little, Alek Pogosyan, Spencer Neal, Ludvic Zrinzo, Marwan Hariz, Thomas Foltynie, Patricia Limousin, Peter Brown
J Vis Exp 2014 ; (89)
PMID: 25077449 [PubMed - as supplied by publisher]


Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study.
Cristina Nombela, James B Rowe, Sophie E Winder-Rhodes, Adam Hampshire, Adrian M Owen, David P Breen, Gordon W Duncan, Tien K Khoo, Alison J Yarnall, Michael J Firbank, Patrick F Chinnery, Trevor W Robbins, John T O'Brien, David J Brooks, David J Burn, , Roger A Barker
Brain 2014 Jul;
PMID: 25080285 [PubMed - as supplied by publisher]


Stimulation of the pedunculopontine nucleus area in Parkinson's disease: effects on speech and intelligibility.
Serge Pinto, Murielle Ferraye, Robert Espesser, Valérie Fraix, Audrey Maillet, Jennifer Guirchoum, Deborah Layani-Zemour, Alain Ghio, Stéphan Chabardès, Pierre Pollak, Bettina Debû
Brain 2014 Jul;
PMID: 25080284 [PubMed - as supplied by publisher]


Blood Genome-Wide Transcriptional Profiles Reflect Broad Molecular Impairments and Strong Blood-Brain Links in Alzheimer's Disease.
Bartholomew J Naughton, F Jason Duncan, Darren A Murrey, Aaron S Meadows, David E Newsom, Nicoleta Stoicea, Peter White, Douglas W Scharre, Douglas M Mccarty, Haiyan Fu
J Alzheimers Dis 2014 Jul;
PMID: 25079797 [PubMed - as supplied by publisher]


Function and expression differences between ergot and non-ergot dopamine D2 agonists on heart valve interstitial cells.
Fumiki Oana, Hiroshi Onozuka, Akihiro Tsuchioka, Takayuki Suzuki, Nobuyuki Tanaka, Kouichi Kaidoh, Yuji Hoyano, Masahiro Hiratochi, Shinji Kikuchi, Yasuo Takehana, Nobuo Shibata
J Heart Valve Dis 2014 Mar; 23(2):246-52
PMID: 25076559 [PubMed - as supplied by publisher]


Therapeutic potential of metabotropic glutamate receptor 4-positive allosteric modulator TAS-4 in rodent models of movement disorders.
Aakanksha Dube, Sumit Chaudhary, Tanaji Mengawade, Chandrashekhar Devidas Upasani
J Neurol Sci 2014 Jul;
PMID: 25073574 [PubMed - as supplied by publisher]


NMDARs in neurological diseases: a potential therapeutic target.
Janneth Gonzalez, Juan Camilo Jurado-Coronel, Marcos Fidel Avila, Angélica Sabogal, Francisco Capani, George E Barreto
Int J Neurosci 2014 Jul;
PMID: 25051426 [PubMed - as supplied by publisher]


The glial response to intracerebrally delivered therapies for neurodegenerative disorders: is this a critical issue?
Francesca Cicchetti, Roger A Barker
Front Pharmacol 2014 ; 5:139
PMID: 25071571 [PubMed - as supplied by publisher]


Subjectively perceived personality and mood changes associated with subthalamic stimulation in patients with Parkinson's disease.
C J Lewis, F Maier, N Horstkötter, A Zywczok, K Witt, C Eggers, T D Meyer, T A Dembek, M Maarouf, E Moro, M Zurowski, C Woopen, J Kuhn, L Timmermann
Psychol Med 2014 May; :1-13
PMID: 25066623 [PubMed - as supplied by publisher]


Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.
Jesse V Veenvliet, Marten P Smidt
Cell Mol Life Sci 2014 Jul;
PMID: 25064061 [PubMed - as supplied by publisher]


The co-occurrence of Alzheimer's disease and Huntington's disease: a neuropathological study of 15 elderly Huntington's disease subjects.
Marie Y Davis, C Dirk Keene, Suman Jayadev, Thomas Bird
J Huntingtons Dis 2014 ; 3(2):209-17
PMID: 25062863 [PubMed - as supplied by publisher]


Correlation of diffusion tensor tractography and intraoperative macrostimulation during deep brain stimulation for Parkinson disease.
Nicholas Said, W Jeff Elias, Prashant Raghavan, Alan Cupino, Nicholas Tustison, Robert Frysinger, James Patrie, Wenjun Xin, Max Wintermark
J Neurosurg 2014 Jul; :1-7
PMID: 25061862 [PubMed - as supplied by publisher]


Systematic analysis of transcription-level effects of neurodegenerative diseases on human brain metabolism by a newly reconstructed brain-specific metabolic network.
Mustafa Sertba?, Kutlu Ulgen, Tunahan Cak?r
FEBS Open Bio 2014 ; 4:542-53
PMID: 25061554 [PubMed - as supplied by publisher]


Neuroprotective Properties of a Standardized Extract from Myracrodruon urundeuva Fr. All. (Aroeira-Do-Sertão), as Evaluated by a Parkinson's Disease Model in Rats.
Iana Calou, Mary Anne Bandeira, Wellida Aguiar-Galvão, Gilberto Cerqueira, Rafaelly Siqueira, Kelly Rose Neves, Gerly Anne Brito, Glauce Viana
Parkinsons Dis 2014 ; 2014:519615
PMID: 25061534 [PubMed - as supplied by publisher]


Glial cell line-derived neurotrophic factor gene delivery via a polyethylene imine grafted chitosan carrier.
Yu-Shiang Peng, Po-Liang Lai, Sydney Peng, His-Chin Wu, Siang Yu, Tsan-Yun Tseng, Li-Fang Wang, I-Ming Chu
Int J Nanomedicine 2014 ; 9:3163-74
PMID: 25061293 [PubMed - as supplied by publisher]


In a Rush to Decide: Deep Brain Stimulation and Dopamine Agonist Therapy in Parkinson's Disease.
Atbin Djamshidian, Sean S O'Sullivan, Alessandro Tomassini, Thomas Foltynie, Patricia Limousin, Iciar Aviles-Olmos, Thomas T Warner, Andrew J Lees, Bruno B Averbeck
J Parkinsons Dis 2014 Jul;
PMID: 25061059 [PubMed - as supplied by publisher]


Correlations between plasma levels of amino acids and nonmotor symptoms in Parkinson's disease.
Qing Tong, Qinrong Xu, Qiang Xia, Yongsheng Yuan, Li Zhang, Hongbin Sun, Han Shan, Kezhong Zhang
J Neural Transm 2014 Jul;
PMID: 25059457 [PubMed - as supplied by publisher]


Modest CaV1.342-selective inhibition by compound 8 is ?-subunit dependent.
Hua Huang, Cheng Yang Ng, Dejie Yu, Jing Zhai, Yulin Lam, Tuck Wah Soong
Nat Commun 2014 ; 5:4481
PMID: 25057870 [PubMed - as supplied by publisher]


Self-unawareness of levodopa induced dyskinesias in patients with Parkinson's disease.
Martina Amanzio, Sara Palermo, Maurizio Zibetti, Daniela Leotta, Rosalba Rosato, Giuliano Geminiani, Leonardo Lopiano
Brain Cogn 2014 Jul; 90C:135-141
PMID: 25058494 [PubMed - as supplied by publisher]