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Treatments/Pipeline

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.

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Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease.
Ilse S Pienaar, Cecilia Heyne Lee, Joanna L Elson, Louisa McGuinness, Stephen M Gentleman, Raj N Kalaria, David T Dexter
Neurobiol Dis 2014 Dec;
PMID: 25533682 [PubMed - as supplied by publisher]


Melatonin Redox Activity. Its Potential Clinical application in Neurodegenerative Disorders.
El?bieta Miller, Agnieszka Morel, Joanna Saluk
Curr Top Med Chem 2014 Dec;
PMID: 25496271 [PubMed - as supplied by publisher]


Environmental enrichment: Evidence for an unexpected therapeutic influence.
Robert J Kotloski, Thomas P Sutula
Exp Neurol 2014 Dec; 264C:121-126
PMID: 25483395 [PubMed - as supplied by publisher]


Cannabinoid CB1 receptors activation and coactivation with D2 receptors modulate GABAergic neurotransmission in the globus pallidus and increase motor asymmetry.
Guadalupe Muńoz-Arenas, Francisco Paz-Bermúdez, Ana Báez-Cordero, René Caballero-Florán, Brenda González-Hernández, Benjamín Florán, I Daniel Limón
Synapse 2014 Dec;
PMID: 25522178 [PubMed - as supplied by publisher]


5-HT1A receptor-dependent control of nigrostriatal dopamine neurotransmission in the pharmacotherapy of Parkinson's disease and schizophrenia.
Darakhshan J Haleem
Behav Pharmacol 2015 Feb; 26(1 and 2):45-58
PMID: 25503261 [PubMed - as supplied by publisher]


Synthesis and Pharmacological Evaluation of Dual Acting Ligands Targeting the Adenosine A2A and Dopamine D2 Receptors for the Potential Treatment of Parkinson's Disease.
Manuela Jörg, Lauren T May, Frankie S Mak, Kiew Ching K Lee, Neil D Miller, Peter J Scammells, Ben Capuano
J Med Chem 2014 Dec;
PMID: 25490054 [PubMed - as supplied by publisher]


Intrastriatal transplantation of adult human neural crest-derived stem cells improves functional outcome in parkinsonian rats.
Janine Müller, Christiana Ossig, Johannes F W Greiner, Stefan Hauser, Mareike Fauser, Darius Widera, Christian Kaltschmidt, Alexander Storch, Barbara Kaltschmidt
Stem Cells Transl Med 2015 Jan; 4(1):31-43
PMID: 25479965 [PubMed - as supplied by publisher]


Human Olfactory Bulb Neural Stem Cells Mitigate Movement Disorders in a Rat Model of Parkinson's disease.
Hany E S Marei, Samah Lashen, Amany Farag, Asma Althani, Nahla Afifi, A Abd-Elmaksoud, Shaymaa Rezk, Roberto Pallini, Patrizia Casalbore, Carlo Cenciarelli
J Cell Physiol 2014 Dec;
PMID: 25536543 [PubMed - as supplied by publisher]


Enhanced efficacy of human brain-derived neural stem cells by transplantation of cell aggregates in a rat model of Parkinson's disease.
Eun Sil Shin, Onyou Hwang, Yu-Shik Hwang, Jun-Kyo Francis Suh, Young Il Chun, Sang Ryong Jeon
J Korean Neurosurg Soc 2014 Nov; 56(5):383-9
PMID: 25535514 [PubMed - as supplied by publisher]


Vitamin C Facilitates Dopamine Neuron Differentiation in Fetal Midbrain Through Tet1- aND Jmjd3-Dependent Epigenetic Control Manner.
Xi-Biao He, Mirang Kim, Seon-Young Kim, Sang-Hoon Yi, Yong-Hee Rhee, Taeho Kim, Eun-Hye Lee, Chang-Hwan Park, Shilpy Dixit, Fiona E Harrison, Sang-Hun Lee
Stem Cells 2014 Dec;
PMID: 25535150 [PubMed - as supplied by publisher]


Potential transbuccal delivery of l-DOPA methylester prodrug: stability in the environment of the oral cavity and ability to cross the mucosal tissue.
Anna Lisa Scaturro, Viviana De Caro, Giuseppina Campisi, Libero Italo Giannola
Drug Deliv 2014 Dec; :1-8
PMID: 25533875 [PubMed - as supplied by publisher]


Progressive brain metabolic changes under deep brain stimulation of subthalamic nucleus in parkinsonian rats.
Christophe Melon, Carine Chassain, Guy Bielicki, Jean-Pierre Renou, Lydia Kerkerian-Le Goff, Pascal Salin, Franck Durif
J Neurochem 2014 Dec;
PMID: 25533782 [PubMed - as supplied by publisher]


TMS Enhances Retention of a Motor Skill in Parkinson's Disease.
Clara Moisello, Daniella Blanco, Cecilia Fontanesi, Jing Lin, Milton Biagioni, Pawan Kumar, Miroslaw Brys, Andrea Loggini, Lucio Marinelli, Giovanni Abbruzzese, Angelo Quartarone, Giulio Tononi, Alessandro Di Rocco, Maria Felice Ghilardi,
Brain Stimul 2014 Nov;
PMID: 25533243 [PubMed - as supplied by publisher]


Prolonged treatment with pramipexole promotes physical interaction of striatal dopamine D3 autoreceptors with dopamine transporters to reduce dopamine uptake.
Javier Castro-Hernández, Domingo Afonso-Oramas, Ignacio Cruz-Muros, Josmar Salas-Hernández, Pedro Barroso-Chinea, Rosario Moratalla, Mark J Millan, Tomás González-Hernández
Neurobiol Dis 2014 Dec; 74C:325-335
PMID: 25511804 [PubMed - as supplied by publisher]


Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats.
A A Martinez, M G Morgese, A Pisanu, T Macheda, M A Paquette, A Seillier, T Cassano, A R Carta, A Giuffrida
Neurobiol Dis 2014 Dec; 74C:295-304
PMID: 25486547 [PubMed - as supplied by publisher]


Automatic behavior in Parkinson's disease.
Keiko Fusegi, Asako Yoritaka, Nobutaka Hattori, Hideo Mori
Parkinsonism Relat Disord 2015 Jan; 21(1):84-5
PMID: 25466403 [PubMed - as supplied by publisher]


Deep brain stimulation and oropharyngeal dysfunction in Parkinson's disease: A case report.
Pichet Termsarasab, Winona Tse
Parkinsonism Relat Disord 2015 Jan; 21(1):79-80
PMID: 25465743 [PubMed - as supplied by publisher]


Proficient motor impulse control in Parkinson disease patients with impulsive and compulsive behaviors.
Daniel O Claassen, Wery P M van den Wildenberg, Madaline B Harrison, Nelleke C van Wouwe, Kristen Kanoff, Joseph S Neimat, Scott A Wylie
Pharmacol Biochem Behav 2014 Nov; 129C:19-25
PMID: 25459105 [PubMed - as supplied by publisher]


Cancer risks among the users of ergot-derived dopamine agonists for Parkinson's disease, a nationwide population-based survey.
Vinchi Wang, Tzu-Hao Chao, Chung-Chih Hsieh, Che-Chen Lin, Chia-Hung Kao
Parkinsonism Relat Disord 2015 Jan; 21(1):18-22
PMID: 25457814 [PubMed - as supplied by publisher]


Effects of Physical Exercise on Neuroinflammation, Neuroplasticity, Neurodegeneration, and Behavior: What We Can Learn From Animal Models in Clinical Settings.
Martina Svensson, Jan Lexell, Tomas Deierborg
Neurorehabil Neural Repair 2014 Dec;
PMID: 25527485 [PubMed - as supplied by publisher]


Proceedings of the Second Annual Deep Brain Stimulation Think Tank: What's in the Pipeline.
Aysegul Gunduz, Hokuto Morita, P Justin Rossi, William L Allen, Ron L Alterman, Helen Bronte-Stewart, Christopher R Butson, David Charles, Sjaak Deckers, Coralie de Hemptinne, Mahlon DeLong, Darin Dougherty, Jens Ellrich, Kelly D Foote, James Giordano, Wayne Goodman, Benjamin D Greenberg, David Greene, Robert Gross, Jack W Judy, Edward Karst, Alexander Kent, Brian Kopell, Anthony Lang, Andres Lozano, Codrin Lungu, Kelly E Lyons, Andre Machado, Hubert Martens, Cameron McIntyre, Hoon-Ki Min, Joseph Neimat, Jill Ostrem, Sat Pannu, Francisco Ponce, Nader Pouratian, Donnie Reymers, Lauren Schrock, Sameer Sheth, Ludy Shih, Scott Stanslaski, G Karl Steinke, Paul Stypulkowski, Alexander I Tröster, Leo Verhagen, Harrison Walker, Michael S Okun
Int J Neurosci 2014 Dec; :1-31
PMID: 25526555 [PubMed - as supplied by publisher]


Small molecule-mediated stabilization of vesicle-associated helical ?-synuclein inhibits pathogenic misfolding and aggregation.
Luis Fonseca-Ornelas, Sybille E Eisbach, Maria Paulat, Karin Giller, Claudio O Fernández, Tiago F Outeiro, Stefan Becker, Markus Zweckstetter
Nat Commun 2014 ; 5:5857
PMID: 25524885 [PubMed - as supplied by publisher]


Abberant protein synthesis in G2019S LRRK2 Drosophila Parkinson disease-related phenotypes.
Ian Martin, Leire Abalde-Atristain, Jungwoo Wren Kim, Ted M Dawson, Valina L Dawson
Fly (Austin) 2014 Jul; 8(3):165-9
PMID: 25483009 [PubMed - as supplied by publisher]


A Novel Bio-Orthogonal Cross-Linker for Improved Protein/Protein Interaction Analysis.
Catherine Nury, Virginie Redeker, Sebastien Dautrey, Anthony Romieu, Guillaume Van Der Rest, Pierre-Yves Renard, Ronald Melki, Julia Chamot-Rooke
Anal Chem 2014 Dec;
PMID: 25522193 [PubMed - as supplied by publisher]


Combining cell transplants or gene therapy with deep brain stimulation for Parkinson's disease.
Nathan C Rowland, Philip A Starr, Paul S Larson, Jill L Ostrem, William J Marks, Daniel A Lim
Mov Disord 2014 Dec;
PMID: 25521796 [PubMed - as supplied by publisher]


Factors contributing to malnutrition in patients with Parkinson's disease.
Sung R Kim, Sun J Chung, Sung-Hee Yoo
Int J Nurs Pract 2014 Dec;
PMID: 25521723 [PubMed - as supplied by publisher]


Mutations in the glucocerebrosidase gene are responsible for Chinese patients with Parkinson's disease.
Zhe Yu, Ting Wang, Jun Xu, Wei Wang, Guifang Wang, Chao Chen, Lili Zheng, Li Pan, Dianrong Gong, Xueli Li, Huaiqian Qu, Fang Li, Bin Zhang, Weidong Le, Fabin Han
J Hum Genet 2014 Dec;
PMID: 25518742 [PubMed - as supplied by publisher]


Activated astrocytes enhance the dopaminergic differentiation of stem cells and promote brain repair through bFGF.
Fan Yang, Yunhui Liu, Jie Tu, Jun Wan, Jie Zhang, Bifeng Wu, Shanping Chen, Jiawei Zhou, Yangling Mu, Liping Wang
Nat Commun 2014 ; 5:5627
PMID: 25517983 [PubMed - as supplied by publisher]


Embryonic stem cells in neurology - current clinical transplantation trials in Parkinson's (PD) and Huntington's (HD) disease.
William Omar Contreras Lopez, Guido Nikkhah, Jaroslaw Maciaczyk
Arq Neuropsiquiatr 2014 Dec; 72(12):978-9
PMID: 25517648 [PubMed - as supplied by publisher]


Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.
Shane Grealish, Elsa Diguet, Agnete Kirkeby, Bengt Mattsson, Andreas Heuer, Yann Bramoulle, Nadja Van Camp, Anselme L Perrier, Philippe Hantraye, Anders Björklund, Malin Parmar
Cell Stem Cell 2014 Nov; 15(5):653-65
PMID: 25517469 [PubMed - as supplied by publisher]


Developing stem cell therapies for Parkinson's disease: waiting until the time is right.
Roger A Barker
Cell Stem Cell 2014 Nov; 15(5):539-42
PMID: 25517462 [PubMed - as supplied by publisher]


Unprecedented Therapeutic Potential with a Combination of A2A/NR2B Receptor Antagonists as Observed in the 6-OHDA Lesioned Rat Model of Parkinson's Disease.
Anne Michel, Patrick Downey, Jean-Marie Nicolas, Dieter Scheller
PLoS One 2014 ; 9(12):e114086
PMID: 25513815 [PubMed - as supplied by publisher]


Rasagiline, a Suicide Inhibitor of Monoamine Oxidases, Binds Reversibly to ?-Synuclein.
Joe Kakish, Omid Tavassoly, Jeremy S Lee
ACS Chem Neurosci 2014 Dec;
PMID: 25514361 [PubMed - as supplied by publisher]


Levodopa/benserazide microsphere (LBM) prevents L-dopa induced dyskinesia by inactivation of the DR1/PKA/P-tau pathway in 6-OHDA-lesioned Parkinson's rats.
Cheng-Long Xie, Wen-Wen Wang, Su-Fang Zhang, Ming-Lu Yuan, Jun-Yi Che, Jing Gan, Lu Song, Wei-En Yuan, Zhen-Guo Liu
Sci Rep 2014 ; 4:7506
PMID: 25511986 [PubMed - as supplied by publisher]


Stiff-person syndrome: insights into a complex autoimmune disorder.
José Fidel Baizabal-Carvallo, Joseph Jankovic
J Neurol Neurosurg Psychiatry 2014 Dec;
PMID: 25511790 [PubMed - as supplied by publisher]


Anterior cingulate dopamine turnover and behavior change in Parkinson's disease.
Catherine L Gallagher, Brian Bell, Matthew Palotti, Jen Oh, Bradley T Christian, Ozioma Okonkwo, Jitka Sojkova, Laura Buyan-Dent, Robert J Nickles, Sandra J Harding, Charles K Stone, Sterling C Johnson, James E Holden
Brain Imaging Behav 2014 Dec;
PMID: 25511521 [PubMed - as supplied by publisher]


Molecular mechanisms of placebo responses in humans.
M Pecińa, J-K Zubieta
Mol Psychiatry 2014 Dec;
PMID: 25510510 [PubMed - as supplied by publisher]


Recurrent Falls in People with Parkinson's Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors.
Lorena R S Almeida, Guilherme T Valença, Nádja N Negreiros, Elen B Pinto, Jamary Oliveira-Filho
Parkinsons Dis 2014 ; 2014:432924
PMID: 25506466 [PubMed - as supplied by publisher]


Sleep disturbances in drug naďve Parkinson's disease (PD) patients and effect of levodopa on sleep.
Teresa Ferreira, Sudesh Prabhakar, Parampreet S Kharbanda
Ann Indian Acad Neurol 2014 Oct; 17(4):416-9
PMID: 25506163 [PubMed - as supplied by publisher]


Pathophysiology and treatment of alien hand syndrome.
Harini Sarva, Andres Deik, William Lawrence Severt
Tremor Other Hyperkinet Mov (N Y) 2014 ; 4:241
PMID: 25506043 [PubMed - as supplied by publisher]


Parkinson's disease: low-dose haloperidol increases dopamine receptor sensitivity and clinical response.
Craig J Hudson, Philip Seeman, Mary V Seeman
Parkinsons Dis 2014 ; 2014:684973
PMID: 25506040 [PubMed - as supplied by publisher]


Coordinated reset stimulation in a large-scale model of the STN-GPe circuit.
Martin Ebert, Christian Hauptmann, Peter A Tass
Front Comput Neurosci 2014 ; 8:154
PMID: 25505882 [PubMed - as supplied by publisher]


Auditory musical hallucinations associated with extended-release pramipexole in an elderly patient with Parkinson's disease.
Hiroshi Kataoka, Satoshi Ueno
Medicine (Baltimore) 2014 Dec; 93(27):e251
PMID: 25501095 [PubMed - as supplied by publisher]


Validity and Efficacy of Screening Algorithms for Assessing Deep Brain Stimulation Candidacy in Parkinson Disease.
Robert R Coleman, Vikas Kotagal, Parag G Patil, Kelvin L Chou
Mov Disord Clin Pract (Hoboken) 2014 Dec; 1(4):342-347
PMID: 25505791 [PubMed - as supplied by publisher]


Dopamine regulates distinctively the activity patterns of striatal output neurons in advanced parkinsonian primates.
Arun Singh, Li Liang, Yoshiki Kaneoke, Xuebing Cao, Stella M Papa
J Neurophysiol 2014 Dec; :jn.00910.2014
PMID: 25505120 [PubMed - as supplied by publisher]


Interleaved programming of subthalamic deep brain stimulation to avoid adverse effects and preserve motor benefit in Parkinson's disease.
Adolfo Ramirez-Zamora, Max Kahn, Joannalee Campbell, Priscilla DeLaCruz, Julie G Pilitsis
J Neurol 2014 Dec;
PMID: 25504447 [PubMed - as supplied by publisher]


Improved dopamine transporter binding activity after bone marrow mesenchymal stem cell transplantation in a rat model of Parkinson's disease: small animal positron emission tomography study with F-18 FP-CIT.
Bok-Nam Park, Jang-Hee Kim, Kwanjae Lee, So Hyun Park, Young-Sil An
Eur Radiol 2014 Dec;
PMID: 25504429 [PubMed - as supplied by publisher]


Medication Adherence in Patients with Parkinson's Disease.
Naveed Malek, Donald G Grosset
CNS Drugs 2014 Dec;
PMID: 25503824 [PubMed - as supplied by publisher]


Levodopa: Effect on cell death and the natural history of Parkinson's disease.
C Warren Olanow
Mov Disord 2014 Dec;
PMID: 25502620 [PubMed - as supplied by publisher]


Neuroprotective and neurorestorative activities of a novel iron chelator-brain selective monoamine oxidase-A/monoamine oxidase-B inhibitor in animal models of Parkinson's disease and aging.
Orit Bar-Am, Tamar Amit, Lana Kupershmidt, Yuval Aluf, Danit Mechlovich, Hoda Kabha, Lena Danovitch, Vincent R Zurawski, Moussa B H Youdim, Orly Weinreb
Neurobiol Aging 2014 Oct;
PMID: 25499799 [PubMed - as supplied by publisher]


Dopamine D3 receptor agonists as pharmacological tools.
S Kassel, J S Schwed, H Stark
Eur Neuropsychopharmacol 2014 Nov;
PMID: 25498414 [PubMed - as supplied by publisher]


Design, characterization, and evaluation of intranasal delivery of ropinirole-loaded mucoadhesive nanoparticles for brain targeting.
Omidreza Jafarieh, Shadab Md, Mushir Ali, Sanjula Baboota, J K Sahni, Bhavna Kumari, Aseem Bhatnagar, Javed Ali
Drug Dev Ind Pharm 2014 Dec; :1-8
PMID: 25496439 [PubMed - as supplied by publisher]


Long-term, Open-label, Safety Study of Once-daily Ropinirole Extended/Prolonged Release in Early and Advanced Parkinson's Disease.
Clare W Makumi, Afsaneh Asgharian, Jeffrey Ellis, Soraya Shaikh, Teri Jimenez, Susan VanMeter
Int J Neurosci 2014 Dec; :1-30
PMID: 25495896 [PubMed - as supplied by publisher]


Activation of ?7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: Implications for Parkinson's disease.
Yuan Liu, Xiaoning Zeng, Yujian Hui, Chenlei Zhu, Jie Wu, Devin H Taylor, Juan Ji, Weimin Fan, Zuhu Huang, Jun Hu
Neuropharmacology 2014 Dec;
PMID: 25486621 [PubMed - as supplied by publisher]


The impact of levodopa-carbidopa intestinal gel on health-related quality of life in Parkinson's disease].
Norbert Kovács, Zsuzsanna Aschermann, Péter Ács, Edit Bosnyák, Gabriella Deli, József Janszky, Sámuel Komoly
Ideggyogy Sz 2014 Jul; 67(7-8):245-50
PMID: 25509365 [PubMed - as supplied by publisher]


Surviving 10 years with deep brain stimulation for Parkinson's disease - a follow-up of 79 patients.
M Bang Henriksen, E L Johnsen, N Sunde, A Vase, M C Gjelstrup, K Ostergaard
Eur J Neurol 2014 Dec;
PMID: 25492023 [PubMed - as supplied by publisher]


Comparative efficacy of selegiline versus rasagiline in the treatment of early Parkinson's disease.
W H Jost, M Friede, J Schnitker
Eur Rev Med Pharmacol Sci 2014 Nov; 18(22):3349
PMID: 25491607 [PubMed - as supplied by publisher]


Behavioral effects of levodopa.
Isabelle Beaulieu-Boire, Anthony E Lang
Mov Disord 2014 Dec;
PMID: 25491470 [PubMed - as supplied by publisher]


The medical treatment of Parkinson disease from James Parkinson to George Cotzias.
Stanley Fahn
Mov Disord 2014 Dec;
PMID: 25491387 [PubMed - as supplied by publisher]


Laparoscopic-assisted percutaneous endoscopic transgastrostomy jejunostomy.
Mihail-Gabriel Dimofte, Vlad Porumb, Simona Nicolescu, Irina Ristescu, Sorinel Lunca
JSLS 2014 Oct; 18(4)
PMID: 25489214 [PubMed - as supplied by publisher]


Imaging of complications from hematopoietic stem cell transplant.
Tarun Pandey, Suresh Maximin, Puneet Bhargava
Indian J Radiol Imaging 2014 Oct; 24(4):327-38
PMID: 25489126 [PubMed - as supplied by publisher]


Clinical spectrum of levodopa-induced complications.
Camila Catherine Aquino, Susan H Fox
Mov Disord 2014 Dec;
PMID: 25488260 [PubMed - as supplied by publisher]


Levodopa: 50 years of a revolutionary drug for Parkinson disease.
Stanley Fahn, Werner Poewe
Mov Disord 2014 Dec;
PMID: 25488146 [PubMed - as supplied by publisher]


Multidisciplinary care with deep brain stimulation for Parkinson's disease patients.
Y F Cheung
Hong Kong Med J 2014 Dec; 20(6):472-3
PMID: 25488032 [PubMed - as supplied by publisher]


Four pioneers of L-dopa treatment: Arvid Carlsson, Oleh Hornykiewicz, George Cotzias, and Melvin Yahr.
Andrew J Lees, Eduardo Tolosa, C Warren Olanow
Mov Disord 2014 Dec;
PMID: 25488030 [PubMed - as supplied by publisher]


The modulatory role of subthalamic nucleus in cognitive functions - A viewpoint.
Ivan Rektor, Martina Bo?ková, Jan Chrastina, Irena Rektorová, Marek Balá?
Clin Neurophysiol 2014 Nov;
PMID: 25487910 [PubMed - as supplied by publisher]


Droxidopa for the Short-Term Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Parkinson's Disease (nOH306B).
Robert A Hauser, Stuart Isaacson, Jerome P Lisk, L Arthur Hewitt, Gerry Rowse
Mov Disord 2014 Dec;
PMID: 25487613 [PubMed - as supplied by publisher]


No Sex Differences in Use of Dopaminergic Medication in Early Parkinson Disease in the US and Canada - Baseline Findings of a Multicenter Trial.
Chizoba C Umeh, Adriana Pérez, Erika F Augustine, Rohit Dhall, Richard B Dewey, Zoltan Mari, David K Simon, Anne-Marie A Wills, Chadwick W Christine, Jay S Schneider, Oksana Suchowersky
PLoS One 2014 ; 9(12):e112287
PMID: 25486269 [PubMed - as supplied by publisher]


Behavioral phenotyping of parkin-deficient mice: looking for early preclinical features of Parkinson's disease.
Daniel Rial, Adalberto A Castro, Nuno Machado, Pedro Garçăo, Francisco Q Gonçalves, Henrique B Silva, Angelo R Tomé, Attila Köfalvi, Olga Corti, Rita Raisman-Vozari, Rodrigo A Cunha, Rui D Prediger
PLoS One 2014 ; 9(12):e114216
PMID: 25486126 [PubMed - as supplied by publisher]


Biotherapies for Parkinson disease.
P Remy
Rev Neurol (Paris) 2014 Dec; 170(12):763-9
PMID: 25459116 [PubMed - as supplied by publisher]


A method for predicting the outcomes of combined pharmacologic and deep brain stimulation therapy for Parkinson's disease.
Reuben R Shamir, Trygve Dolbert, Angela M Noecker, Anneke M Frankemolle, Benjamin L Walter, Cameron C McIntyre
Med Image Comput Comput Assist Interv 2014 ; 17(Pt 2):188-95
PMID: 25513510 [PubMed - as supplied by publisher]


Betting on DBS: Effects of Subthalamic Nucleus Deep Brain Stimulation on Risk Taking and Decision Making in Patients With Parkinson's Disease.
Jason Brandt, Mark Rogerson, Haya Al-Joudi, Gila Reckess, Barnett Shpritz, Chizoba C Umeh, Noha Aljehani, Kelly Mills, Zoltan Mari
Neuropsychology 2014 Dec;
PMID: 25486385 [PubMed - as supplied by publisher]


Dopamine heteroreceptor complexes as therapeutic targets in Parkinson's disease.
Kjell Fuxe, Diego Guidolin, Luigi F Agnati, Dasiel O Borroto-Escuela
Expert Opin Ther Targets 2014 Dec; :1-22
PMID: 25486101 [PubMed - as supplied by publisher]


A method for predicting the outcomes of combined pharmacologic and deep brain stimulation therapy for Parkinson's disease.
Reuben R Shamir, Trygve Dolbert, Angela M Noecker, Anneke M Frankemolle, Benjamin L Walter, Cameron C McIntyre
Med Image Comput Comput Assist Interv 2014 ; 17(Pt 2):188-95
PMID: 25485378 [PubMed - as supplied by publisher]


Parkinson's disease: carbidopa, nausea, and dyskinesia.
Marty Hinz, Alvin Stein, Ted Cole
Clin Pharmacol 2014 ; 6:189-94
PMID: 25484598 [PubMed - as supplied by publisher]


Autophagy and ethanol neurotoxicity.
Jia Luo
Autophagy 2014 Nov; :0
PMID: 25484085 [PubMed - as supplied by publisher]


Constipation is reduced by beta-blockers and increased by dopaminergic medications in Parkinson's disease.
Gennaro Pagano, Echo E Tan, Janelle M Haider, Alyssa Bautista, Michele Tagliati
Parkinsonism Relat Disord 2014 Nov;
PMID: 25483722 [PubMed - as supplied by publisher]


Therapeutic strategies to prevent and manage dyskinesias in Parkinson's disease.
Manuela Pilleri, Angelo Antonini
Expert Opin Drug Saf 2014 Dec; :1-14
PMID: 25483147 [PubMed - as supplied by publisher]


Gene therapy for Parkinson's disease: still a hot topic?
Jeffrey H Kordower
Neuropsychopharmacology 2015 Jan; 40(1):255-6
PMID: 25482182 [PubMed - as supplied by publisher]


Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease.
Gael Le Douaron, Fanny Schmidt, Majid Amar, Hanane Kadar, Lucila Debortoli, Alexandra Latini, Blandine Séon-Méniel, Laurent Ferrié, Patrick Pierre Michel, David Touboul, Alain Brunelle, Rita Raisman-Vozari, Bruno Figadčre
Eur J Med Chem 2015 Jan; 89:467-79
PMID: 25462259 [PubMed - as supplied by publisher]


In silico design of novel 2H-chromen-2-one derivatives as potent and selective MAO-B inhibitors.
Leonardo Pisani, Roberta Farina, Orazio Nicolotti, Domenico Gadaleta, Ramon Soto-Otero, Marco Catto, Mario Di Braccio, Estefania Mendez-Alvarez, Angelo Carotti
Eur J Med Chem 2015 Jan; 89:98-105
PMID: 25462230 [PubMed - as supplied by publisher]


Rasagiline and Pisa syndrome in Parkinson's disease patients.
Paolo Solla, Antonino Cannas, Gianni Orofino, Francesco Marrosu
Neurol Sci 2014 Dec;
PMID: 25481627 [PubMed - as supplied by publisher]


The effect of levodopa on postural stability evaluated by wearable inertial measurement units for idiopathic and vascular Parkinson's disease.
Miguel F Gago, Vitor Fernandes, Jaime Ferreira, Hélder Silva, Maria L Rodrigues, Luís Rocha, Estela Bicho, Nuno Sousa
Gait Posture 2014 Nov;
PMID: 25480163 [PubMed - as supplied by publisher]


Reprint of "iPSCs, aging and age-related diseases"
Ken-Ichi Isobe, Zhao Cheng, Naomi Nishio, Thanasegan Suganya, Yuriko Tanaka, Sachiko Ito
N Biotechnol 2014 Nov; 32(1):169-179
PMID: 25479728 [PubMed - as supplied by publisher]


Novel Formulations and Modes of Delivery of Levodopa.
Werner Poewe, Angelo Antonini
Mov Disord 2014 Dec;
PMID: 25476691 [PubMed - as supplied by publisher]


Linking neuroscience with modern concepts of impulse control disorders in Parkinson's disease.
T Celeste Napier, Jean-Christophe Corvol, Anthony A Grace, Jamie D Roitman, James Rowe, Valerie Voon, Antonio P Strafella
Mov Disord 2014 Dec;
PMID: 25476402 [PubMed - as supplied by publisher]


Identification of candidate genes for Parkinson's disease through blood transcriptome analysis in LRRK2-G2019S carriers, idiopathic cases, and controls.
Jon Infante, Carlos Prieto, María Sierra, Pascual Sánchez-Juan, Isabel González-Aramburu, Coro Sánchez-Quintana, José Berciano, Onofre Combarros, Jesús Sainz
Neurobiol Aging 2014 Nov;
PMID: 25475535 [PubMed - as supplied by publisher]


Deep brain stimulation in multiple system atrophy mimicking idiopathic Parkinson's disease.
Navamayooran Thavanesan, Martin Gillies, Michael Farrell, Alex L Green, Tipu Aziz
Case Rep Neurol 2014 Sep; 6(3):232-7
PMID: 25473395 [PubMed - as supplied by publisher]


Zirconium oxide ceramic foam: a promising supporting biomaterial for massive production of glial cell line-derived neurotrophic factor.
Zhong-Wei Liu, Wen-Qiang Li, Jun-Kui Wang, Xian-Cang Ma, Chen Liang, Peng Liu, Zheng Chu, Yong-Hui Dang
J Zhejiang Univ Sci B 2014 Dec; 15(12):1013-22
PMID: 25471830 [PubMed - as supplied by publisher]


Noninvasive Bioluminescence Imaging of ?-Synuclein Oligomerization in Mouse Brain Using Split Firefly Luciferase Reporters.
Sarah-Ann Aelvoet, Abdelilah Ibrahimi, Francesca Macchi, Rik Gijsbers, Chris Van den Haute, Zeger Debyser, Veerle Baekelandt
J Neurosci 2014 Dec; 34(49):16518-32
PMID: 25471588 [PubMed - as supplied by publisher]


Acute and Chronic Mood and Apathy Outcomes from a Randomized Study of Unilateral STN and GPi DBS.
Michael S Okun, Samuel S Wu, Sarah Fayad, Herbert Ward, Dawn Bowers, Christian Rosado, Lauren Bowen, Charles Jacobson, Christopher Butson, Kelly D Foote
PLoS One 2014 ; 9(12):e114140
PMID: 25469706 [PubMed - as supplied by publisher]


Levodopa: the story continues].
Zh Nevrol Psikhiatr Im S S Korsakova 2014 ; 114(9):93-9
PMID: 25513357 [PubMed - as supplied by publisher]


Levodopa: the story continues].
Zh Nevrol Psikhiatr Im S S Korsakova 2014 ; 114(9):93-9
PMID: 25473661 [PubMed - as supplied by publisher]


Gait and attentional performance in freezers under methylphenidate.
A Delval, C Moreau, S Bleuse, D Guehl, E Bestaven, E Guillaud, K Dujardin, L Defebvre, D Devos
Gait Posture 2014 Oct;
PMID: 25468682 [PubMed - as supplied by publisher]


Brain-derived neurotrophic factor expression increases after enzyme replacement therapy in Gaucher disease.
Filippo Vairo, Fernanda Sperb-Ludwig, Matheus Wilke, Kristiane Michellin-Tirelli, Cristina Netto, Eurico Camargo Neto, Ida Vanessa Doederlein Schwartz
J Neuroimmunol 2014 Nov;
PMID: 25468270 [PubMed - as supplied by publisher]


Wide-bore 1.5T MRI-guided deep brain stimulation surgery: initial experience and technique comparison.
Karl A Sillay, Deborah Rusy, Laura Buyan-Dent, Nancy L Ninman, Karl K Vigen
Clin Neurol Neurosurg 2014 Dec; 127:79-85
PMID: 25459248 [PubMed - as supplied by publisher]


Targeting glutamatergic synapses in Parkinson's disease.
Fabrizio Gardoni, Monica Di Luca
Curr Opin Pharmacol 2014 Nov; 20C:24-28
PMID: 25462288 [PubMed - as supplied by publisher]


Lmx1a enhances the effect of iNSCs in a PD model.
Jianyu Wu, Chao Sheng, Zhongfeng Liu, Weili Jia, Bin Wang, Mo Li, Linlin Fu, Zhenhua Ren, Jing An, Lisi Sang, Gongru Song, Yanchuan Wu, Yanling Xu, Shuyan Wang, Zhiguo Chen, Qi Zhou, Y Alex Zhang
Stem Cell Res 2014 Oct; 14(1):1-9
PMID: 25460246 [PubMed - as supplied by publisher]


Outcomes, management, and potential mechanisms of interleaving deep brain stimulation settings.
Svjetlana Miocinovic, Pravin Khemani, Rebecca Whiddon, Pam Zeilman, Daniel Martinez-Ramirez, Michael S Okun, Shilpa Chitnis
Parkinsonism Relat Disord 2014 Oct; 20(12):1434-1437
PMID: 25457819 [PubMed - as supplied by publisher]


Peripheral nervous system involvement in Parkinson's disease: Evidence and controversies.
C Comi, L Magistrelli, G D Oggioni, M Carecchio, T Fleetwood, R Cantello, F Mancini, A Antonini
Parkinsonism Relat Disord 2014 Oct; 20(12):1329-1334
PMID: 25457816 [PubMed - as supplied by publisher]