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Featured Research

Can we predict who is at risk of facing cognitive issues in PD and address them earlier? These are the questions being pursued by Dr. Goldman of the PDF Research Center at Rush University Medical Center.

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Treatments/Pipeline

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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WebBioBank: A new platform for integrating clinical forms and shared neurosignal analyses to support multi-centre studies in Parkinson's Disease.
Elena Rossi, Manuela Rosa, Lorenzo Rossi, Alberto Priori, Sara Marceglia
J Biomed Inform 2014 Sep;
PMID: 25205596 [PubMed - as supplied by publisher]


Antibodies and protein misfolding: From structural research tools to therapeutic strategies.
Erwin De Genst, Anne Messer, Christopher M Dobson
Biochim Biophys Acta 2014 Sep;
PMID: 25194824 [PubMed - as supplied by publisher]


Differential impact of thalamic versus subthalamic deep brain stimulation on lexical processing.
Lea K Krugel, Felicitas Ehlen, Hannes O Tiedt, Andrea A Kühn, Fabian Klostermann
Neuropsychologia 2014 Sep; 63C:175-184
PMID: 25194209 [PubMed - as supplied by publisher]


Increased neurotrophic factor levels in ventral mesencephalic cultures do not explain the protective effect of osteopontin and the synthetic 15-mer RGD domain against MPP+ toxicity.
Lauren Broom, Peter Jenner, Sarah Rose
Exp Neurol 2014 Sep;
PMID: 25218309 [PubMed - as supplied by publisher]


Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice.
Dalila Mango, Alessandra Bonito-Oliva, Ada Ledonne, Loredana Cappellacci, Riccardo Petrelli, Robert Nisticò, Nicola Berretta, Gilberto Fisone, Nicola Biagio Mercuri
Exp Neurol 2014 Aug; 261C:733-743
PMID: 25173217 [PubMed - as supplied by publisher]


Angiotensin type 1 receptor blockage reduces l-dopa-induced dyskinesia in the 6-OHDA model of Parkinson's disease. Involvement of vascular endothelial growth factor and interleukin-1?
Ana Muñoz, Pablo Garrido-Gil, Antonio Dominguez-Meijide, Jose L Labandeira-Garcia
Exp Neurol 2014 Aug; 261C:720-732
PMID: 25160895 [PubMed - as supplied by publisher]


Resting state cortical oscillations of PD patients without and with Subthalamic deep brain stimulation, a MEG study.
Chunyan Cao, Dianyou Li, Tianxiao Jiang, Nuri Firat Ince, Shikun Zhan, Jing Zhang, Zhiyi Sha, Bomin Sun
J Clin Neurophysiol 2014 Sep;
PMID: 25233246 [PubMed - as supplied by publisher]


Beta-coupled high-frequency activity and Beta-locked neuronal spiking in the subthalamic nucleus of Parkinson's disease.
Andrew I Yang, Nora Vanegas, Codrin Lungu, Kareem A Zaghloul
J Neurosci 2014 Sep; 34(38):12816-27
PMID: 25232117 [PubMed - as supplied by publisher]


GDNF-Transfected Macrophages Produce Potent Neuroprotective Effects in Parkinson's Disease Mouse Model.
Yuling Zhao, Matthew J Haney, Richa Gupta, John P Bohnsack, Zhijian He, Alexander V Kabanov, Elena V Batrakova
PLoS One 2014 ; 9(9):e106867
PMID: 25229627 [PubMed - as supplied by publisher]


Cholinergic System Dysfunction and Neurodegenerative Diseases: Cause or Effect?
A M Tata, L Velluto, C D'Angelo, M Reale
CNS Neurol Disord Drug Targets 2014 Sep;
PMID: 25230223 [PubMed - as supplied by publisher]


Human epidermal neural crest stem cells as candidates for cell-based therapies, disease modeling, and drug discovery.
Maya Sieber-Blum
Birth Defects Res C Embryo Today 2014 Sep;
PMID: 25228472 [PubMed - as supplied by publisher]


Subthalamic nucleus-deep brain stimulation for early motor complications in Parkinson's disease-the EARLYSTIM trial: Early is not always better.
Tiago A Mestre, Alberto J Espay, Connie Marras, Mark H Eckman, Pierre Pollak, Anthony E Lang
Mov Disord 2014 Sep;
PMID: 25227325 [PubMed - as supplied by publisher]


Quantitative evaluation of parkinsonian rigidity during intra-operative deep brain stimulation.
Yuri Kwon, Sang-Hoon Park, Ji-Won Kim, Yeji Ho, Hyeong-Min Jeon, Min-Jung Bang, Seong-Beom Koh, Jong-Hyun Kim, Gwang-Moon Eom
Biomed Mater Eng 2014 Jan; 24(6):2273-81
PMID: 25226927 [PubMed - as supplied by publisher]


Early-onset Parkinson's disease due to PINK1 p.Q456X mutation - Clinical and functional study.
Joanna Siuda, Barbara Jasinska-Myga, Magdalena Boczarska-Jedynak, Grzegorz Opala, Fabienne C Fiesel, Elisabeth L Moussaud-Lamodière, Leslie A Scarffe, Valina L Dawson, Owen A Ross, Wolfdieter Springer, Ted M Dawson, Zbigniew K Wszolek
Parkinsonism Relat Disord 2014 Sep;
PMID: 25226871 [PubMed - as supplied by publisher]


Effects of STN DBS and auditory cueing on the performance of sequential movements and the occurrence of action tremor in Parkinson's disease.
Tjitske Heida, Eva Christine Wentink, Yan Zhao, Enrico Marani
J Neuroeng Rehabil 2014 ; 11(1):135
PMID: 25212111 [PubMed - as supplied by publisher]


Discovery of high-frequency deep brain stimulation for treatment of Parkinson disease: 2014 Lasker Award.
Mahlon R DeLong, Alim-Louis Benabid
JAMA 2014 Sep; 312(11):1093-4
PMID: 25198255 [PubMed - as supplied by publisher]


Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration.
Elpida Tsika, Meghna Kannan, Caroline Shi-Yan Foo, Dustin Dikeman, Liliane Glauser, Sandra Gellhaar, Dagmar Galter, Graham W Knott, Ted M Dawson, Valina L Dawson, Darren J Moore
Neurobiol Dis 2014 Aug; 71C:345-358
PMID: 25174890 [PubMed - as supplied by publisher]


Loss of dopamine disrupts circadian rhythms in a mouse model of Parkinson's disease.
Karim Fifel, Howard M Cooper
Neurobiol Dis 2014 Aug; 71C:359-369
PMID: 25171792 [PubMed - as supplied by publisher]


Clinical implications of local field potentials for understanding and treating movement disorders.
John A Thompson, David Lanctin, Nuri Firat Ince, Aviva Abosch
Stereotact Funct Neurosurg 2014 ; 92(4):251-63
PMID: 25170784 [PubMed - as supplied by publisher]


Cholinesterase inhibitors for Parkinson's disease: a systematic review and meta-analysis.
Gennaro Pagano, Giuseppe Rengo, Giuseppe Pasqualetti, Grazia Daniela Femminella, Fabio Monzani, Nicola Ferrara, Michele Tagliati
J Neurol Neurosurg Psychiatry 2014 Sep;
PMID: 25224676 [PubMed - as supplied by publisher]


Initial medication in patients of newly diagnosed Parkinson's disease in taiwan.
Yi-Jen Guo, Yi-Chu Liao, Ching-Heng Lin, Ming-Hong Chang
PLoS One 2014 ; 9(9):e107465
PMID: 25222829 [PubMed - as supplied by publisher]


Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.
Wei Lu, Senthilkumar S Karuppagounder, Danielle A Springer, Michele D Allen, Lixin Zheng, Brittany Chao, Yan Zhang, Valina L Dawson, Ted M Dawson, Michael Lenardo
Nat Commun 2014 ; 5:4930
PMID: 25222142 [PubMed - as supplied by publisher]


Parkinson disease: Let's listen to patients with PD after deep brain stimulation.
Elena Moro
Nat Rev Neurol 2014 Sep;
PMID: 25201237 [PubMed - as supplied by publisher]


Understanding the Structural Requirements of Hybrid (S)-6-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol and its Analogs as D2/D3 Receptor Ligands: A Three-Dimensional Quantitative Structure-Activity Relationship (3D QSAR) Investigation.
Gyan Modi, Horrick Sharma, Prashant S Kharkar, Aloke K Dutta
Medchemcomm 2014 Sep; 5(9):1384-1399
PMID: 25221669 [PubMed - as supplied by publisher]


A mouse model of non-motor symptoms in Parkinson's disease: focus on pharmacological interventions targeting affective dysfunctions.
Alessandra Bonito-Oliva, Débora Masini, Gilberto Fisone
Front Behav Neurosci 2014 ; 8:290
PMID: 25221486 [PubMed - as supplied by publisher]


Alterations in Polysomnographic (PSG) profile in drug-naïve Parkinson's disease.
Sanju P Joy, Sanjib Sinha, Pramod Kumar Pal, Samhita Panda, Mariamma Philip, Arun B Taly
Ann Indian Acad Neurol 2014 Jul; 17(3):287-91
PMID: 25221397 [PubMed - as supplied by publisher]


VMAT2 and Parkinson's disease: harnessing the dopamine vesicle.
Kelly M Lohr, Gary W Miller
Expert Rev Neurother 2014 Sep; :1-3
PMID: 25220836 [PubMed - as supplied by publisher]


Protective role of olesoxime against wild type alpha-synuclein-induced toxicity in human neuronally differentiated SHSY-5Y cells.
C Gouarné, J Tracz, M Giraudon Paoli, V Deluca, M Seimandi, G Tardif, M Xilouri, L Stefanis, T Bordet, R M Pruss
Br J Pharmacol 2014 Sep;
PMID: 25220617 [PubMed - as supplied by publisher]


Mutations in Niemann Pick type C gene are risk factor for Alzheimer's disease.
Nikola Kresojevi?, Valerija Dobri?i?, Marina Svetel, Vladimir Kosti?
Med Hypotheses 2014 Sep;
PMID: 25220527 [PubMed - as supplied by publisher]


Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites.
Kevin T Stroupe, Frances M Weaver, Lishan Cao, Dolores Ippolito, Brandon R Barton, Inger E Burnett-Zeigler, Robert G Holloway, Barbara G Vickrey, Tanya Simuni, Kenneth A Follett
Mov Disord 2014 Sep;
PMID: 25220042 [PubMed - as supplied by publisher]


Indolinone based LRRK2 kinase inhibitors with a key hydrogen bond.
Stefan Göring, Jean-Marc Taymans, Veerle Baekelandt, Boris Schmidt
Bioorg Med Chem Lett 2014 Aug;
PMID: 25219901 [PubMed - as supplied by publisher]


Mania with Psychotic Feature Induced by the use of Pramipexole in Parkinson's Disease: A Case Report].
Ceren Meriç, Efruz Pirdo?an, Omür Günday Toker, Atilla Tekin, Bahad?r Bak?m, Selime Celik
Turk Psikiyatri Derg 2014 ; 25(3):212-4
PMID: 25219695 [PubMed - as supplied by publisher]


Apoptosis signal-regulating kinase 1 modulates the phenotype of ?-synuclein transgenic mice.
Kang-Woo Lee, Jong-Min Woo, Joo-Young Im, Eun S Park, Liqiang He, Hidenori Ichijo, Eunsung Junn, M Maral Mouradian
Neurobiol Aging 2014 Jul;
PMID: 25219466 [PubMed - as supplied by publisher]


Pharmacokinetic/pharmacodynamic evaluation of rasagiline mesylate for Parkinson's disease.
Thomas Müller
Expert Opin Drug Metab Toxicol 2014 Oct; 10(10):1423-32
PMID: 25196265 [PubMed - as supplied by publisher]


A Novel Method for Removal of Deep Brain Stimulation Artifact from Electroencephalography.
Yinming Sun, Faranak Farzan, Luis Garcia Dominguez, Mera S Barr, Peter Giacobbe, Andres M Lozano, Willy Wong, Zafiris J Daskalakis
J Neurosci Methods 2014 Sep;
PMID: 25218560 [PubMed - as supplied by publisher]


Cortico-muscular coherence in advanced Parkinson's disease with deep brain stimulation.
Katja Airaksinen, Jyrki P Mäkelä, Jussi Nurminen, Jarkko Luoma, Samu Taulu, Antti Ahonen, Eero Pekkonen
Clin Neurophysiol 2014 Aug;
PMID: 25218364 [PubMed - as supplied by publisher]


'Don't delay, start today': delaying levodopa does not delay motor complications.
Susan H Fox, Anthony E Lang
Brain 2014 Oct; 137(Pt 10):2628-30
PMID: 25217790 [PubMed - as supplied by publisher]


Effects of deep brain stimulation on pain and other nonmotor symptoms in Parkinson disease.
Rubens G Cury, Ricardo Galhardoni, Erich T Fonoff, Maria G Dos Santos Ghilardi, Fernanda Fonoff, Debora Arnaut, Martin L Myczkowski, Marco A Marcolin, Edson Bor-Seng-Shu, Egberto R Barbosa, Manoel J Teixeira, Daniel Ciampi de Andrade
Neurology 2014 Sep;
PMID: 25217059 [PubMed - as supplied by publisher]


Stem cells for cell replacement therapy: A therapeutic strategy for HD?
Anne Rosser, Clive N Svendsen
Mov Disord 2014 Sep; 29(11):1446-54
PMID: 25216372 [PubMed - as supplied by publisher]


From anatomy to electrophysiology: clinical lasker goes deep.
Huda Y Zoghbi
Cell 2014 Sep; 158(6):1225-9
PMID: 25215480 [PubMed - as supplied by publisher]


Rotigotine: The first new chemical entity for transdermal drug delivery.
Donald A McAfee, Jonathan Hadgraft, Majella E Lane
Eur J Pharm Biopharm 2014 Aug;
PMID: 25173087 [PubMed - as supplied by publisher]


Detecting associations between behavioral addictions and dopamine agonists in the Food & Drug Administration's Adverse Event database.
Katherine E Gendreau, Marc N Potenza
J Behav Addict 2014 Mar; 3(1):21-6
PMID: 25215211 [PubMed - as supplied by publisher]


Dopaminergic agents and nutritional status in Parkinson's disease.
Alice Laudisio, Davide L Vetrano, Eleonora Meloni, Diego Ricciardi, Francesco Franceschi, Anna Rita Bentivoglio, Roberto Bernabei, Giuseppe Zuccalà
Mov Disord 2014 Sep;
PMID: 25214286 [PubMed - as supplied by publisher]


Supranuclear eye movement disorders.
João Lemos, Eric Eggenberger
Curr Opin Ophthalmol 2014 Sep;
PMID: 25211041 [PubMed - as supplied by publisher]


Anesthetic challenges for deep brain stimulation: a systematic approach.
Rajkalyan Chakrabarti, Mahmood Ghazanwy, Anurag Tewari
N Am J Med Sci 2014 Aug; 6(8):359-69
PMID: 25210668 [PubMed - as supplied by publisher]


Three Mechanisms by which Striatal Denervation Causes Breakdown of Dopamine Signaling.
Jakob K Dreyer
J Neurosci 2014 Sep; 34(37):12444-56
PMID: 25209283 [PubMed - as supplied by publisher]


Norepinephrine Transporter Inhibition with Desipramine Exacerbates L-DOPA-induced Dyskinesia: Role for Synaptic Dopamine Regulation in Denervated Nigrostriatal Terminals.
Tanya Chotibut, Victoria Fields, Michael F Salvatore
Mol Pharmacol 2014 Sep;
PMID: 25208966 [PubMed - as supplied by publisher]


Motion Sensor Dyskinesia Assessment During Activities of Daily Living.
Christopher L Pulliam, Michelle A Burack, Dustin A Heldman, Joseph P Giuffrida, Thomas O Mera
J Parkinsons Dis 2014 Sep;
PMID: 25208729 [PubMed - as supplied by publisher]


Dual Small-Molecule Targeting of SMAD Signaling Stimulates Human Induced Pluripotent Stem Cells toward Neural Lineages.
Methichit Wattanapanitch, Nuttha Klincumhom, Porntip Potirat, Rattaya Amornpisutt, Chanchao Lorthongpanich, Yaowalak U-Pratya, Chuti Laowtammathron, Pakpoom Kheolamai, Niphon Poungvarin, Surapol Issaragrisil
PLoS One 2014 ; 9(9):e106952
PMID: 25207966 [PubMed - as supplied by publisher]


Concomitant Use of Acetylcholine Esterase Inhibitors and Urinary Antispasmodics Among Finnish Community-Dwelling Persons With Alzheimer Disease.
Sanna Torvinen-Kiiskinen, Heidi Taipale, Antti Tanskanen, Jari Tiihonen, Sirpa Hartikainen
J Clin Psychopharmacol 2014 Sep;
PMID: 25207860 [PubMed - as supplied by publisher]


Zhichan decoction induces differentiation of dopaminergic neurons in Parkinson's disease rats after neural stem cell transplantation.
Huifen Shi, Jie Song, Xuming Yang
Neural Regen Res 2014 May; 9(9):931-6
PMID: 25206914 [PubMed - as supplied by publisher]


Compound Formula Rehmannia alleviates levodopa-induced dyskinesia in Parkinson's disease.
Long Teng, Fang Hong, Chenguang Zhang, Jiancheng He, Haiying Wang
Neural Regen Res 2014 Feb; 9(4):407-12
PMID: 25206828 [PubMed - as supplied by publisher]


Vascular changes caused by deep brain stimulation using double-dose gadolinium-enhanced brain MRI.
Byeong Sam Choi, Yong Hwan Kim, Sang Ryong Jeon
Neural Regen Res 2014 Feb; 9(3):276-9
PMID: 25206812 [PubMed - as supplied by publisher]


Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies.
Meyer Mylène, Montel Sébastien, Colnat-Coulbois Sophie, Lerond Jérôme, Potheegadoo Jevita, Vidailhet Pierre, Gospodaru Nicolaie, Vespignani Hervé, Barroche Gérard, Spitz Elisabeth, Schwan Raymund
Neural Regen Res 2013 Oct; 8(30):2856-67
PMID: 25206607 [PubMed - as supplied by publisher]


How do Chinese medicines that tonify the kidney inhibit dopaminergic neuron apoptosis?
Shaogang Lin, Shuifen Ye, Jinmu Huang, Yun Tian, Yihui Xu, Mengqi Wu, Jingxia Wang, Songying Wu, Jing Cai
Neural Regen Res 2013 Oct; 8(30):2820-6
PMID: 25206603 [PubMed - as supplied by publisher]


The neuropsychological assessment battery categories test as a measure of executive dysfunction in patients with Parkinson's disease and essential tremor: an exploratory study.
Jared Benge, Jacqueline Phillips-Sabol, Richard Phenis
Clin Neuropsychol 2014 Aug; 28(6):1008-18
PMID: 25181389 [PubMed - as supplied by publisher]


Deranged NMDAergic cortico-subthalamic transmission underlies parkinsonian motor deficits.
Ming-Kai Pan, Chun-Hwei Tai, Wen-Chuan Liu, Ju-Chun Pei, Wen-Sung Lai, Chung-Chin Kuo
J Clin Invest 2014 Sep;
PMID: 25202982 [PubMed - as supplied by publisher]


The nature of tremor circuits in parkinsonian and essential tremor.
Hayriye Cagnan, Simon Little, Thomas Foltynie, Patricia Limousin, Ludvic Zrinzo, Marwan Hariz, Binith Cheeran, James Fitzgerald, Alexander L Green, Tipu Aziz, Peter Brown
Brain 2014 Sep;
PMID: 25200741 [PubMed - as supplied by publisher]


Withdrawing amantadine in dyskinetic patients with Parkinson disease: The AMANDYSK trial.
Joseph H Friedman, Fabienne Ory-Magne, Olivier Rascol
Neurology 2014 Sep; 83(11):1035-6
PMID: 25200717 [PubMed - as supplied by publisher]


Pathogenetic mechanisms of dementia in the older patients with Parkinson's diseases].
Zh Nevrol Psikhiatr Im S S Korsakova 2014 ; 114(7):79-82
PMID: 25202788 [PubMed - as supplied by publisher]


Mutations in the ATP13A2 Gene and Parkinsonism: A Preliminary Review.
Xinglong Yang, Yanming Xu
Biomed Res Int 2014 ; 2014:371256
PMID: 25197640 [PubMed - as supplied by publisher]


Hippocampal proliferation is increased in presymptomatic Parkinson's disease and due to microglia.
Karlijn J Doorn, Benjamin Drukarch, Anne-Marie van Dam, Paul J Lucassen
Neural Plast 2014 ; 2014:959154
PMID: 25197578 [PubMed - as supplied by publisher]


Anaesthetic management of a patient with deep brain stimulation implant for radical nephrectomy.
Monica Khetarpal, Monu Yadav, Dilip Kulkarni, R Gopinath
Indian J Anaesth 2014 Jul; 58(4):461-3
PMID: 25197118 [PubMed - as supplied by publisher]


Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy.
Travis B Lewis, Joel N Glasgow, Ashley S Harms, David G Standaert, David T Curiel
Viruses 2014 Aug; 6(8):3293-310
PMID: 25196484 [PubMed - as supplied by publisher]


Interhemispheric functional interactions between the subthalamic nuclei of patients with Parkinson's disease.
F U Hohlefeld, C Huchzermeyer, J Huebl, G-H Schneider, C Brücke, T Schönecker, A A Kühn, G Curio, V V Nikulin
Eur J Neurosci 2014 Sep;
PMID: 25195608 [PubMed - as supplied by publisher]


Closed loop deep brain stimulation: an evolving technology.
Md Kamal Hosain, Abbas Kouzani, Susannah Tye
Australas Phys Eng Sci Med 2014 Sep;
PMID: 25195055 [PubMed - as supplied by publisher]


Basal ganglia: physiological, behavioral, and computational studies.
Ahmed A Moustafa, Izhar Bar-Gad, Alon Korngreen, Hagai Bergman
Front Syst Neurosci 2014 ; 8:150
PMID: 25191233 [PubMed - as supplied by publisher]


Corrigendum: Advances in non-dopaminergic pharmacological treatments of Parkinson's disease.
Sandy Stayte, Bryce Vissel
Front Neurosci 2014 ; 8:254
PMID: 25191219 [PubMed - as supplied by publisher]


Striatal Astrocytes Act as a Reservoir for L-DOPA.
Masato Asanuma, Ikuko Miyazaki, Shinki Murakami, Francisco J Diaz-Corrales, Norio Ogawa
PLoS One 2014 ; 9(9):e106362
PMID: 25188235 [PubMed - as supplied by publisher]


Deep brain stimulation.
X L Chen, Y Y Xiong, G L Xu, X F Liu
Interv Neurol 2013 Sep; 1(3-4):200-12
PMID: 25187779 [PubMed - as supplied by publisher]


Pooled analysis of phase III with entacapone in Parkinson's disease.
M Kuoppamäki, M Vahteristo, J Ellmén, K Kieburtz
Acta Neurol Scand 2014 Sep;
PMID: 25186800 [PubMed - as supplied by publisher]


Clinical, positron emission tomography, and pathological studies of DNAJC13 p.N855S Parkinsonism.
Silke Appel-Cresswell, Ali H Rajput, Vesna Sossi, Christina Thompson, Vanessa Silva, Jessamyn McKenzie, Katherine Dinelle, Siobhan E McCormick, Carles Vilariño-Güell, A Jon Stoessl, Dennis W Dickson, Chris A Robinson, Matthew J Farrer, Alex Rajput
Mov Disord 2014 Sep;
PMID: 25186792 [PubMed - as supplied by publisher]


The Cardiovascular Actions of DOPA Mediated by the Gene Product of ocular albinism 1.
Yoshio Goshima, Fumio Nakamura, Daiki Masukawa, Sandy Chen, Motokazu Koga
J Pharmacol Sci 2014 Sep;
PMID: 25185585 [PubMed - as supplied by publisher]


Neuropsychological changes following deep brain stimulation surgery for Parkinson's disease: comparisons of treatment at pallidal and subthalamic targets versus best medical therapy.
Johannes C Rothlind, Michele K York, Kim Carlson, Ping Luo, William J Marks, Frances M Weaver, Matthew Stern, Kenneth Follett, Domenic Reda,
J Neurol Neurosurg Psychiatry 2014 Sep;
PMID: 25185211 [PubMed - as supplied by publisher]


Cerebellum in levodopa-induced dyskinesias: the unusual suspect in the motor network.
Asha Kishore, Traian Popa
Front Neurol 2014 ; 5:157
PMID: 25183959 [PubMed - as supplied by publisher]


Development and evaluation of buccal films impregnated with selegiline-loaded nanospheres.
Bandar E Al-Dhubiab, Anroop B Nair, Rachna Kumria, Mahesh Attimarad, Sree Harsha
Drug Deliv 2014 Sep; :1-9
PMID: 25182182 [PubMed - as supplied by publisher]


Genetic diagnosis of two dopa-responsive dystonia families by exome sequencing.
Zhan-Fang Sun, Yu-Han Zhang, Ji-Feng Guo, Qi-Ying Sun, Jun-Pu Mei, Han-Lin Zhou, Li-Ping Guan, Jin-Yong Tian, Zheng-Mao Hu, Jia-da Li, Kun Xia, Xin-Xiang Yan, Bei-Sha Tang
PLoS One 2014 ; 9(9):e106388
PMID: 25181484 [PubMed - as supplied by publisher]


Regionally-specified second trimester fetal neural stem cells reveals differential neurogenic programming.
Yiping Fan, Guillaume Marcy, Eddy S M Lee, Steve Rozen, Citra N Z Mattar, Simon N Waddington, Eyleen L K Goh, Mahesh Choolani, Jerry K Y Chan
PLoS One 2014 ; 9(9):e105985
PMID: 25181041 [PubMed - as supplied by publisher]


Zinc-finger Nuclease Enhanced Gene Targeting in Human Embryonic Stem Cells.
Brigham J Hartley, Stewart A Fabb, Ben A L Finnin, John M Haynes, Colin W Pouton
J Vis Exp 2014 ; (90)
PMID: 25177806 [PubMed - as supplied by publisher]


A-31The Effects of Rasagiline on Cognition in Mild to Moderate Stage Parkinson's Disease, A Double-Blind Placebo Controlled Study.
L Frakey, J Friedman
Arch Clin Neuropsychol 2014 Sep; 29(6):514
PMID: 25176693 [PubMed - as supplied by publisher]


A-27Differences in Cognitive Abilities among Fallers and Non-Fallers in Parkinson's Disease.
D Denney, D Brown, J Galusha, C Lobue, R Dewey, L Lacritz
Arch Clin Neuropsychol 2014 Sep; 29(6):513
PMID: 25176689 [PubMed - as supplied by publisher]


Effects of the Adenosine A2A Receptor Antagonist on Cognitive Dysfunction in Parkinson's Disease.
Shin-Ichi Uchida, Takako Kadowaki-Horita, Tomoyuki Kanda
Int Rev Neurobiol 2014 ; 119:169-89
PMID: 25175966 [PubMed - as supplied by publisher]


Clinical/Pharmacological Aspect of Adenosine A2A Receptor Antagonist for Dyskinesia.
Tomoyuki Kanda, Shin-Ichi Uchida
Int Rev Neurobiol 2014 ; 119:127-50
PMID: 25175964 [PubMed - as supplied by publisher]


Adenosine receptors and dyskinesia in pathophysiology.
Masahiko Tomiyama
Int Rev Neurobiol 2014 ; 119:117-26
PMID: 25175963 [PubMed - as supplied by publisher]


An Overview of Adenosine A2A Receptor Antagonists in Parkinson's Disease.
Peter Jenner
Int Rev Neurobiol 2014 ; 119:71-86
PMID: 25175961 [PubMed - as supplied by publisher]


Side-Effect Profile of Serotoninergic Treatments for Parkinson's Disease and L-DOPA-induced Dyskinesia in Rats.
D Lindenbach, N Palumbo, C Y Ostock, N Vilceus, M M Conti, C Bishop
Br J Pharmacol 2014 Sep;
PMID: 25175895 [PubMed - as supplied by publisher]


Botulinum toxin type a potentiates the effect of neuromotor rehabilitation of Pisa syndrome in Parkinson disease: A placebo controlled study.
C Tassorelli, R De Icco, E Alfonsi, M Bartolo, M Serrao, M Avenali, I De Paoli, C Conte, N G Pozzi, P Bramanti, G Nappi, G Sandrini
Parkinsonism Relat Disord 2014 Aug;
PMID: 25175601 [PubMed - as supplied by publisher]


Cost-effectiveness of subthalmic nucleus deep brain stimulation for treatment of advanced Parkinson's disease in Hong Kong : a prospective study.
X L Zhu, Danny Tm Chan, Claire Ky Lau, Wai S Poon, Vincent Ct Mok, Anne Yy Chan, Lawrence Ks Wong, Jonas Hm Yeung, Michael Cm Leung, Venus Yh Tang, Rosanna Km Wong, Carol Yeung
World Neurosurg 2014 Aug;
PMID: 25175275 [PubMed - as supplied by publisher]


Methods for assessing the regenerative responses of neural tissue.
Steven W Poser, Maria Adele Rueger, Andreas Androutsellis-Theotokis
Methods Mol Biol 2014 ; 1213:293-302
PMID: 25173392 [PubMed - as supplied by publisher]


A new feature extraction method and classification of early stage Parkinsonian rats with and without DBS treatment.
B Iravani, F Towhidkhah, M Roghani
Australas Phys Eng Sci Med 2014 Aug;
PMID: 25173488 [PubMed - as supplied by publisher]


AQW051, a novel and selective nicotinic acetylcholine receptor ?7 partial agonist, reduces l-Dopa-induced dyskinesias and extends the duration of l-Dopa effects in parkinsonian monkeys.
Thérèse Di Paolo, Laurent Grégoire, Dominik Feuerbach, Walid Elbast, Markus Weiss, Baltazar Gomez-Mancilla
Parkinsonism Relat Disord 2014 May;
PMID: 25172125 [PubMed - as supplied by publisher]


The Rationale Driving the Evolution of Deep Brain Stimulation to Constant-Current Devices.
Jeff M Bronstein, Michele Tagliati, Cameron McIntyre, Robert Chen, Tyler Cheung, Eric L Hargreaves, Zvi Israel, Michael Moffitt, Erwin B Montgomery, Paul Stypulkowski, Jay Shils, Timothy Denison, Jerrold Vitek, Jens Volkman, Jeffrey Wertheimer, Michael S Okun
Neuromodulation 2014 Aug;
PMID: 25171762 [PubMed - as supplied by publisher]


Neurostimulation for traumatic brain injury.
Samuel S Shin, C Edward Dixon, David O Okonkwo, R Mark Richardson
J Neurosurg 2014 Aug; :1-13
PMID: 25170668 [PubMed - as supplied by publisher]


Polyneuropathy associated with duodenal infusion of levodopa in Parkinson's disease: features, pathogenesis and management.
Antonino Uncini, Roberto Eleopra, Marco Onofrj
J Neurol Neurosurg Psychiatry 2014 Aug;
PMID: 25168395 [PubMed - as supplied by publisher]


Phenotypic variability of PINK1 expression: 12 Years' clinical follow-up of two Italian families.
Lucia Ricciardi, Simona Petrucci, Arianna Guidubaldi, Tamara Ialongo, Laura Serra, Alessandro Ferraris, Barbara Spanò, Marco Bozzali, Enza Maria Valente, Anna Rita Bentivoglio
Mov Disord 2014 Aug;
PMID: 25164310 [PubMed - as supplied by publisher]


Engineering the Next Generation of Clinical Deep Brain Stimulation Technology.
Cameron C McIntyre, Ashutosh Chaturvedi, Reuben R Shamir, Scott F Lempka
Brain Stimul 2014 Jul;
PMID: 25161150 [PubMed - as supplied by publisher]


Modulation of the Cerebello-thalamo-cortical Network in Thalamic Deep Brain Stimulation for Tremor: A Diffusion Tensor Imaging Study.
Volker Arnd Coenen, Niels Allert, Sebastian Paus, Martin Kronenbürger, Horst Urbach, Burkhard Mädler
Neurosurgery 2014 Aug;
PMID: 25161000 [PubMed - as supplied by publisher]


Treatment of aging vocal folds: surgical approaches.
Yutomo Seino, Jacqui E Allen
Curr Opin Otolaryngol Head Neck Surg 2014 Aug;
PMID: 25160615 [PubMed - as supplied by publisher]


Comparing neuroprotective effects of CDNF-expressing bone marrow derived mesenchymal stem cells via differing routes of administration utilizing an in vivo model of Parkinson's disease.
Mei Jiaming, Chaoshi Niu
Neurol Sci 2014 Aug;
PMID: 25159816 [PubMed - as supplied by publisher]


Gene Therapy for the Nervous System: Challenges and New Strategies.
Casey A Maguire, Servio H Ramirez, Steven F Merkel, Miguel Sena-Esteves, Xandra O Breakefield
Neurotherapeutics 2014 Aug;
PMID: 25159276 [PubMed - as supplied by publisher]