Adjust Text Size:change font sizechange font sizechange font sizechange font sizechange font sizechange font size

Light of Day Foundation Challenge

Light of Day Challenge

Goal: $100,000

Raised: $47,987

 

Donate Now

 

Featured Research

PDF-funded Brain banks

Scientists are making inroads because thousands of people with Parkinson’s and their family members have donated their brains to science, including to PDF-supported programs at Columbia University Medical Center and Rush University Medical Center.

Learn More

PDF Grant Programs

Are you interested in furthering Parkinson's science? View PDF's open grant programs.

Learn More


Treatments/Pipeline

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.

There was an error retrieving the document. Please try again.

Functional Role of Parkin against Oxidative Stress in Neural Cells.
Minyoung Hwang, Ja-Myong Lee, Younghwa Kim, Dongho Geum
Endocrinol Metab (Seoul) 2014 Mar; 29(1):62-9
PMID: 24741456 [PubMed - as supplied by publisher]


Neuroprotective effect of Tinospora cordifolia ethanol extract on 6-hydroxy dopamine induced Parkinsonism.
Jayasankar Kosaraju, Santhivardhan Chinni, Partha Deb Roy, Elango Kannan, A Shanish Antony, M N Satish Kumar
Indian J Pharmacol 2014 Mar; 46(2):176-80
PMID: 24741189 [PubMed - as supplied by publisher]


Assessment of postural balance among individuals with Parkinson disease with and without effects from dopaminergic medications.
Júlia Maria D'Andréa Greve, Natália Mariana Silva Luna, Juliana Plato de Siqueira, Cristina Prota, Angélica Castilho Alonso
Am J Phys Med Rehabil 2014 May; 93(5):365-71
PMID: 24739944 [PubMed - as supplied by publisher]


Neuroprotective Potential of Adenosine A2A and Cannabinoid CB1 Receptor Antagonists in an Animal Model of Parkinson Disease.
Silvia Cerri, Giovanna Levandis, Giulia Ambrosi, Elena Montepeloso, Gian Filippo Antoninetti, Rafael Franco, José Luis Lanciego, Younis Baqi, Christa E Müller, Annalisa Pinna, Fabio Blandini, Marie Therese Armentero
J Neuropathol Exp Neurol 2014 May; 73(5):414-24
PMID: 24709676 [PubMed - as supplied by publisher]


Applying anodal tDCS during tango dancing in a patient with Parkinson's disease.
D Kaski, J H Allum, A M Bronstein, R O Dominguez
Neurosci Lett 2014 Mar; 568C:39-43
PMID: 24686184 [PubMed - as supplied by publisher]


Memantine improves attention and episodic memory in Parkinson's disease dementia and dementia with Lewy bodies.
Keith A Wesnes, Dag Aarsland, Clive Ballard, Elisabet Londos
Int J Geriatr Psychiatry 2014 Apr;
PMID: 24737460 [PubMed - as supplied by publisher]


Parkin and PINK1: much more than mitophagy.
Leslie A Scarffe, Daniel A Stevens, Valina L Dawson, Ted M Dawson
Trends Neurosci 2014 Apr;
PMID: 24735649 [PubMed - as supplied by publisher]


Transgenic Expression of Human Glial Cell Line-Derived Neurotrophic Factor from Integration-Deficient Lentiviral Vectors is Neuroprotective in a Rodent Model of Parkinson's Disease.
Ngoc B Lu-Nguyen, Martin Broadstock, Maximilian G Schliesser, Cynthia C Bartholomae, Christof von Kalle, Manfred Schmidt, Rafael J Yáńez-Muńoz
Hum Gene Ther 2014 Apr;
PMID: 24635742 [PubMed - as supplied by publisher]


Subthalamic deep brain stimulation restores automatic response activation and increases susceptibility to impulsive behavior in patients with Parkinson's disease.
Franziska Plessow, Rico Fischer, Jens Volkmann, Torsten Schubert
Brain Cogn 2014 Mar; 87C:16-21
PMID: 24632184 [PubMed - as supplied by publisher]


The "brittle response" to Parkinson's disease medications: characterization and response to deep brain stimulation.
Daniel Martinez-Ramirez, Juan Giugni, Vinata Vedam-Mai, Aparna Wagle Shukla, Irene A Malaty, Nikolaus R McFarland, Ramon L Rodriguez, Kelly D Foote, Michael S Okun
PLoS One 2014 ; 9(4):e94856
PMID: 24733172 [PubMed - as supplied by publisher]


Computation and visualization of risk assessment in deep brain stimulation planning.
Alexandre Bilger, Christian Duriez, Stéphane Cotin
Stud Health Technol Inform 2014 ; 196:29-35
PMID: 24732475 [PubMed - as supplied by publisher]


Optimal target localization for subthalamic stimulation in patients with Parkinson disease.
Marie-Laure Welter, Michael Schüpbach, Virginie Czernecki, Carine Karachi, Sara Fernandez-Vidal, Jean-Louis Golmard, Giulia Serra, Soledad Navarro, Arlette Welaratne, Andréas Hartmann, Valérie Mesnage, Fanny Pineau, Philippe Cornu, Bernard Pidoux, Yulia Worbe, Panayiotis Zikos, David Grabli, Damien Galanaud, Anne-Marie Bonnet, Hayat Belaid, Didier Dormont, Marie Vidailhet, Luc Mallet, Jean-Luc Houeto, Eric Bardinet, Jerome Yelnik, Yves Agid
Neurology 2014 Apr; 82(15):1352-61
PMID: 24647024 [PubMed - as supplied by publisher]


Deep brain stimulation of the medial septum or nucleus accumbens alleviates psychosis-relevant behavior in ketamine-treated rats.
Jingyi Ma, L Stan Leung
Behav Brain Res 2014 Jun; 266:174-82
PMID: 24632470 [PubMed - as supplied by publisher]


H2O2- or l-DOPA-injured dopaminergic neurons trigger the release of soluble mediators that up-regulate striatal GDNF through different signalling pathways.
Carla Pais Fonseca, Susana Gama, Ana Saavedra, Graça Baltazar
Biochim Biophys Acta 2014 Mar; 1842(7):927-934
PMID: 24632468 [PubMed - as supplied by publisher]


Abnormal Bursting as a Pathophysiological Mechanism in Parkinson's Disease.
Cj Lobb
Basal Ganglia 2014 Apr; 3(4):187-195
PMID: 24729952 [PubMed - as supplied by publisher]


Trends in antiparkinsonian medication use in new zealand: 1995-2011.
T L Pitcher, M R Macaskill, T J Anderson
Parkinsons Dis 2014 ; 2014:379431
PMID: 24729910 [PubMed - as supplied by publisher]


Low prevalence of most frequent pathogenic variants of six PARK genes in sporadic Parkinson's disease.
S García, L B López-Hernández, J A Suarez-Cuenca, M Solano-Rojas, M P Gallegos-Arreola, O Gama-Moreno, P Valdez-Anguiano, P Canto, L Dávila-Maldonado, C F Cuevas-García, R M Coral-Vázquez
Folia Neuropathol 2014 ; 52(1):22-9
PMID: 24729340 [PubMed - as supplied by publisher]


Fatigue during an episode of benign paroxysmal positional vertigo.
Lea Pollak, Rafael Stryjer
Eur Arch Otorhinolaryngol 2014 Apr;
PMID: 24728232 [PubMed - as supplied by publisher]


Ribosomal Protein s15 Phosphorylation Mediates LRRK2 Neurodegeneration in Parkinson's Disease.
Ian Martin, Jungwoo Wren Kim, Byoung Dae Lee, Ho Chul Kang, Jin-Chong Xu, Hao Jia, Jeannette Stankowski, Min-Sik Kim, Jun Zhong, Manoj Kumar, Shaida A Andrabi, Yulan Xiong, Dennis W Dickson, Zbigniew K Wszolek, Akhilesh Pandey, Ted M Dawson, Valina L Dawson
Cell 2014 Apr; 157(2):472-85
PMID: 24725412 [PubMed - as supplied by publisher]


Adenosine A2A receptor antagonist istradefylline 20 versus 40 mg/day as augmentation for Parkinson's disease: a meta-analysis.
Chuan Zhu, Guowei Wang, Jinqing Li, Li Chen, Chaoli Wang, Yajie Wang, Ping Lin, Hong Ran
Neurol Res 2014 Apr; :1743132814Y0000000375
PMID: 24725292 [PubMed - as supplied by publisher]


Preventive effect of rikkunshito on gastric motor function inhibited by l-dopa in rats.
Lixin Wang, Sachiko Mogami, Hiroshi Karasawa, Chihiro Yamada, Seiichi Yakabi, Koji Yakabi, Tomohisa Hattori, Yvette Taché
Peptides 2014 Mar; 55C:136-144
PMID: 24631952 [PubMed - as supplied by publisher]


Utilizing fast spin echo MRI to reduce image artifacts and improve implant/tissue interface detection in refractory Parkinson's patients with deep brain stimulators.
Subhendra N Sarkar, Pooja R Sarkar, Efstathios Papavassiliou, Rafael R Rojas
Parkinsons Dis 2014 ; 2014:508576
PMID: 24724036 [PubMed - as supplied by publisher]


Interneurons from embryonic development to cell-based therapy.
Derek G Southwell, Cory R Nicholas, Allan I Basbaum, Michael P Stryker, Arnold R Kriegstein, John L Rubenstein, Arturo Alvarez-Buylla
Science 2014 Apr; 344(6180):1240622
PMID: 24723614 [PubMed - as supplied by publisher]


Challenges in the pharmacotherapeutic management of the hospitalised patient with Parkinson's disease].
U Lertxundi, S Domingo-Echaburu, I Irigoyen, A Isla, M A Solinis, J C Garcia-Monco
Rev Neurol 2014 Apr; 58(8):353-64
PMID: 24723178 [PubMed - as supplied by publisher]


Toxicity and metabolism of layered double hydroxide intercalated with levodopa in a Parkinson's disease model.
Aminu Umar Kura, Nooraini Mohd Ain, Mohd Zobir Hussein, Sharida Fakurazi, Samer Hasan Hussein-Al-Ali
Int J Mol Sci 2014 ; 15(4):5916-27
PMID: 24722565 [PubMed - as supplied by publisher]


Direct endoscopic jejunosotomy for the administration of levodopa-carbidopa intestinal gel in Parkinson's disease.
Thomas E Kimber, Mark Schoeman
Parkinsonism Relat Disord 2014 Mar;
PMID: 24721490 [PubMed - as supplied by publisher]


Safinamide for the treatment of Parkinson's disease.
Livia Dézsi, László Vécsei
Expert Opin Investig Drugs 2014 May; 23(5):729-42
PMID: 24650154 [PubMed - as supplied by publisher]


Predicting the development of levodopa-induced dyskinesias: A presynaptic mechanism?
Peter A Lewitt, M Maral Mouradian
Neurology 2014 Apr;
PMID: 24719487 [PubMed - as supplied by publisher]


Presynaptic dopamine depletion predicts levodopa-induced dyskinesia in de novo Parkinson disease.
Jin Yong Hong, Jungsu S Oh, Injoo Lee, Mun Kyung Sunwoo, Jee Hyun Ham, Ji E Lee, Young H Sohn, Jae Seung Kim, Phil Hyu Lee
Neurology 2014 Apr;
PMID: 24719485 [PubMed - as supplied by publisher]


The subthalamic nucleus modulates the early phase of probabilistic classification learning.
Daniel Weiss, Judith M Lam, Sorin Breit, Alireza Gharabaghi, Rejko Krüger, Andreas R Luft, Tobias Wächter
Exp Brain Res 2014 Apr;
PMID: 24718493 [PubMed - as supplied by publisher]


Inhibition of catechol-o-methyltransferase (COMT) by myricetin, dihydromyricetin, and myricitrin.
Xu Zhu, Yun-Hong Jia
Pharmazie 2014 Mar; 69(3):183-6
PMID: 24716406 [PubMed - as supplied by publisher]


Oscillatory subthalamic nucleus activity is modulated by dopamine during emotional processing in Parkinson's disease.
Julius Huebl, Bernhard Spitzer, Christof Brücke, Thomas Schönecker, Andreas Kupsch, François Alesch, Gerd-Helge Schneider, Andrea A Kühn
Cortex 2014 Mar;
PMID: 24713195 [PubMed - as supplied by publisher]


Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder.
Amy B Hart, Eric R Gamazon, Barbara E Engelhardt, Pamela Sklar, Anna K Kähler, Christina M Hultman, Patrick F Sullivan, Benjamin M Neale, Stephen V Faraone, , Harriet de Wit, Nancy J Cox, Abraham A Palmer
Proc Natl Acad Sci U S A 2014 Apr;
PMID: 24711425 [PubMed - as supplied by publisher]


Measuring Disease Progression in Early Parkinson Disease: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) Experience.
Sotirios A Parashos, Sheng Luo, Kevin M Biglan, Ivan Bodis-Wollner, Bo He, Grace S Liang, G Webster Ross, Barbara C Tilley, Lisa M Shulman,
JAMA Neurol 2014 Apr;
PMID: 24711047 [PubMed - as supplied by publisher]


A dual-tracer study of extrastriatal 6-[(18) F]fluoro-m-tyrosine and 6-[(18) F]-Fluoro-L-dopa uptake in Parkinson's disease.
Clarence Li, Matthew Palotti, James E Holden, Jen Oh, Ozioma Okonkwo, Bradley T Christian, Barbara B Bendlin, Laura Buyan-Dent, Sandra J Harding, Charles K Stone, Onofre T Dejesus, Robert J Nickles, Catherine L Gallagher
Synapse 2014 Apr;
PMID: 24710997 [PubMed - as supplied by publisher]


Subacute peripheral neuropathy under duodopa therapy without cobalamin deficiency and despite supplementation.
Sophie M Lehnerer, Urban M Fietzek, Michael Messner, Andres O Ceballos-Baumann
J Neural Transm 2014 Apr;
PMID: 24710647 [PubMed - as supplied by publisher]


The effect of funding sources on donepezil randomised controlled trial outcome: a meta-analysis.
Lewis O J Killin, Tom C Russ, John M Starr, Sharon Abrahams, Sergio Della Sala
BMJ Open 2014 ; 4(4):e004083
PMID: 24710130 [PubMed - as supplied by publisher]


Effects of dopaminergic therapy on locomotor adaptation and adaptive learning in persons with Parkinson's disease.
Ryan T Roemmich, Nawaz Hack, Umer Akbar, Chris J Hass
Behav Brain Res 2014 Mar;
PMID: 24698798 [PubMed - as supplied by publisher]


iPS cell technologies: significance and applications to CNS regeneration and disease.
Hideyuki Okano, Shinya Yamanaka
Mol Brain 2014 ; 7(1):22
PMID: 24685317 [PubMed - as supplied by publisher]


Sustained Increase of PKA Activity in the Postcommissural Putamen of Dyskinetic Monkeys.
Garikoitz Azkona, Irene Marcilla, Rakel López de Maturana, Amaya Sousa, Esther Pérez-Navarro, Maria-Rosario Luquin, Rosario Sanchez-Pernaute
Mol Neurobiol 2014 Apr;
PMID: 24705818 [PubMed - as supplied by publisher]


Update on deep brain stimulation.
Robert H Howland
J Psychosoc Nurs Ment Health Serv 2014 Apr; 52(4):23-6
PMID: 24702284 [PubMed - as supplied by publisher]


Influence of serum uric acid levels on prognosis and survival in amyotrophic lateral sclerosis: a meta-analysis.
Alon Abraham, Vivian E Drory
J Neurol 2014 Apr;
PMID: 24699859 [PubMed - as supplied by publisher]


Parkinson disease: Gene therapy for Parkinson disease-a hope, or a dream?
C Warren Olanow
Nat Rev Neurol 2014 Apr; 10(4):186-7
PMID: 24662536 [PubMed - as supplied by publisher]


Parkinson disease: A role for serotonergic neurons in levodopa-induced dyskinesia.
Alex Chase
Nat Rev Neurol 2014 Apr; 10(4):180
PMID: 24638137 [PubMed - as supplied by publisher]


Visuomotor adaptation in Parkinson's disease: Effects of perturbation type and medication state.
Jennifer A Semrau, Joel S Perlmutter, Kurt A Thoroughman
J Neurophysiol 2014 Apr;
PMID: 24694937 [PubMed - as supplied by publisher]


Functional Receptors and Intracellular Signal Pathways of Midkine (MK) and Pleiotrophin (PTN).
Chuanying Xu, Shunying Zhu, Mingyuan Wu, Wei Han, Yan Yu
Biol Pharm Bull 2014 ; 37(4):511-20
PMID: 24694599 [PubMed - as supplied by publisher]


Genomic and pharmacogenomic biomarkers of Parkinson's disease.
Hortensia Alonso-Navarro, Felix Javier Jimenez-Jimenez, Elena Garcia-Martin, Jose A G Agundez
Curr Drug Metab 2014 Feb; 15(2):129-81
PMID: 24694231 [PubMed - as supplied by publisher]


Carotid artery thickening and neurocirculatory abnormalities in de novo Parkinson disease.
Joong-Seok Kim, Yoon-Sang Oh, Kwang-Soo Lee, In-Uk Song, In-Seok Park, Dong-Won Yang, Ja-Seong Koo, David S Goldstein
J Neural Transm 2014 Apr;
PMID: 24692006 [PubMed - as supplied by publisher]


Coordinate-based lead location does not predict Parkinson's disease deep brain stimulation outcome.
Kelsey A Nestor, Jacob D Jones, Christopher R Butson, Takashi Morishita, Charles E Jacobson, David A Peace, Dennis Chen, Kelly D Foote, Michael S Okun
PLoS One 2014 ; 9(4):e93524
PMID: 24691109 [PubMed - as supplied by publisher]


Parkinsonian Patients and Poor Awareness of Dyskinesias.
Sara Pietracupa, Anna Latorre, Alfredo Berardelli, Giovanni Fabbrini
Front Neurol 2014 ; 5:32
PMID: 24688482 [PubMed - as supplied by publisher]


Long-term cognitive outcome of bilateral subthalamic deep brain stimulation in Parkinson's disease.
Han-Joon Kim, Beom S Jeon, Sun Ha Paek, Kyoung-Min Lee, Ji-Young Kim, Jee-Young Lee, Hee Jin Kim, Ji Young Yun, Young Eun Kim, Hui-Jun Yang, Gwanhee Ehm
J Neurol 2014 Apr;
PMID: 24687897 [PubMed - as supplied by publisher]


Parkinson's disease: recent advances.
Regina Katzenschlager
J Neurol 2014 Apr;
PMID: 24687891 [PubMed - as supplied by publisher]


Adenosine A2A Receptor Antagonists in Parkinson's Disease: Progress in Clinical Trials from the Newly Approved Istradefylline to Drugs in Early Development and Those Already Discontinued.
Annalisa Pinna
CNS Drugs 2014 Apr;
PMID: 24687255 [PubMed - as supplied by publisher]


Articulatory closure proficiency in Parkinson's disease patients following deep brain stimulation of the subthalamic nucleus and caudal zona incerta.
Fredrik Karlsson, Katarina Olofsson, Patric Blomstedt, Jan Linder, Erik Nordh, Jan van Doorn
J Speech Lang Hear Res 2014 Feb;
PMID: 24686561 [PubMed - as supplied by publisher]


BAX channel activity mediates lysosomal disruption linked to Parkinson disease.
Jordi Bové, Marta Martínez-Vicente, Benjamin Dehay, Celine Perier, Ariadna Recasens, Agnes Bombrun, Bruno Antonsson, Miquel Vila
Autophagy 2014 Mar; 10(5)
PMID: 24686337 [PubMed - as supplied by publisher]


A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions.
Antonio G Zippo, Sara Nencini, Gian Carlo Caramenti, Maurizio Valente, Riccardo Storchi, Gabriele E M Biella
J Vis Exp 2014 ; (85)
PMID: 24686295 [PubMed - as supplied by publisher]


Deep brain stimulation of the subthalamic nucleus improves pain in Parkinson's disease.
Jean Pellaprat, Fabienne Ory-Magne, Cindy Canivet, Marion Simonetta-Moreau, Jean-Albert Lotterie, Fatai Radji, Christophe Arbus, Angélique Gerdelat, Patrick Chaynes, Christine Brefel-Courbon
Parkinsonism Relat Disord 2014 Mar;
PMID: 24685343 [PubMed - as supplied by publisher]


A Cross-Sectional Study on Drug Use in Multiple System Atrophy.
María Verónica Rey, Santiago Perez-Lloret, Anne Pavy-Le Traon, Wassilios G Meissner, Francois Tison, Olivier Rascol
CNS Drugs 2014 Mar;
PMID: 24683045 [PubMed - as supplied by publisher]


Canonical BMP-Smad Signalling Promotes Neurite Growth in Rat Midbrain Dopaminergic Neurons.
Shane V Hegarty, Louise M Collins, Aisling M Gavin, Sarah L Roche, Sean L Wyatt, Aideen M Sullivan, Gerard W O'Keeffe
Neuromolecular Med 2014 Mar;
PMID: 24682653 [PubMed - as supplied by publisher]


Characterization of Cortico-bulbar Pharyngeal Neurophysiology in Dysphagic Patients with Parkinson's Disease.
Emilia Michou, Shaheen Hamdy, Mary Harris, Adil Vania, Jeremy Dick, Mark Kellett, John Rothwell
Clin Gastroenterol Hepatol 2014 Mar;
PMID: 24681075 [PubMed - as supplied by publisher]


Severity of depression and anxiety are predictors of response to antidepressant treatment in Parkinson's disease.
A J H Moonen, A Wijers, A F G Leentjens, C W Christine, S A Factor, J Juncos, J M Lyness, L Marsh, M Panisset, R Pfeiffer, D Rottenberg, C Serrano Ramos, L Shulman, C Singer, J Slevin, W McDonald, P Auinger, I H Richard
Parkinsonism Relat Disord 2014 Mar;
PMID: 24679737 [PubMed - as supplied by publisher]


Methods for Surgical Targeting of the STN in Early-Stage Parkinson's Disease.
Corrie R Camalier, Peter E Konrad, Chandler E Gill, Chris Kao, Michael R Remple, Hana M Nasr, Thomas L Davis, Peter Hedera, Fenna T Phibbs, Anna L Molinari, Joseph S Neimat, David Charles
Front Neurol 2014 ; 5:25
PMID: 24678307 [PubMed - as supplied by publisher]


Effects of antidromic and orthodromic activation of STN afferent axons during DBS in Parkinson's disease: a simulation study.
Guiyeom Kang, Madeleine M Lowery
Front Comput Neurosci 2014 ; 8:32
PMID: 24678296 [PubMed - as supplied by publisher]


Low-Power Inversion Recovery MRI Preserves Brain Tissue Contrast for Patients with Parkinson Disease with Deep Brain Stimulators.
S N Sarkar, E Papavassiliou, R Rojas, D L Teich, D B Hackney, R A Bhadelia, J Stormann, R L Alterman
AJNR Am J Neuroradiol 2014 Mar;
PMID: 24676004 [PubMed - as supplied by publisher]


Daytime sleep in Parkinson's disease measured by episodes of immobility.
K Kotschet, W Johnson, S McGregor, J Kettlewell, A Kyoong, D M O'Driscoll, A R Turton, R I Griffiths, M K Horne
Parkinsonism Relat Disord 2014 Feb;
PMID: 24674770 [PubMed - as supplied by publisher]


Drug treatment of early-stage (de novo and "honeymoon") Parkinson disease.
P Cesaro, L Defebvre
Rev Neurol (Paris) 2014 Mar;
PMID: 24673985 [PubMed - as supplied by publisher]


Two new adenosine receptor antagonists for the treatment of Parkinson's disease: istradefylline versus tozadenant.
Santiago Perez-Lloret, Marcelo Merello
Expert Opin Pharmacother 2014 Mar;
PMID: 24673462 [PubMed - as supplied by publisher]


A rapid thin-layer chromatography bioautographic method for detecting the monoamine oxidase inhibitors in plants.
Ji-Bei Liang, Zhong-Duo Yang, Zong-Mei Shu, Cheng-Cheng Yu
Nat Prod Res 2014 Mar;
PMID: 24673426 [PubMed - as supplied by publisher]


Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation.
Daisuke Doi, Bumpei Samata, Mitsuko Katsukawa, Tetsuhiro Kikuchi, Asuka Morizane, Yuichi Ono, Kiyotoshi Sekiguchi, Masato Nakagawa, Malin Parmar, Jun Takahashi
Stem Cell Reports 2014 Mar; 2(3):337-50
PMID: 24672756 [PubMed - as supplied by publisher]


Disrupting neuronal transmission: mechanism of DBS?
Satomi Chiken, Atsushi Nambu
Front Syst Neurosci 2014 ; 8:33
PMID: 24672437 [PubMed - as supplied by publisher]


A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease: No Evidence of Benefit.
, M Flint Beal, David Oakes, Ira Shoulson, Claire Henchcliffe, Wendy R Galpern, Richard Haas, Jorge L Juncos, John G Nutt, Tiffini Smith Voss, Bernard Ravina, Clifford M Shults, Karen Helles, Victoria Snively, Mark F Lew, Brian Griebner, Arthur Watts, Shan Gao, Emmanuelle Pourcher, Louisette Bond, Katie Kompoliti, Pinky Agarwal, Cherissa Sia, Mandar Jog, Linda Cole, Munira Sultana, Roger Kurlan, Irene Richard, Cheryl Deeley, Cheryl H Waters, Angel Figueroa, Ani Arkun, Matthew Brodsky, William G Ondo, Christine B Hunter, Joohi Jimenez-Shahed, Alicia Palao, Janis M Miyasaki, Julie So, James Tetrud, Liza Reys, Katharine Smith, Carlos Singer, Anita Blenke, David S Russell, Candace Cotto, Joseph H Friedman, Margaret Lannon, Lin Zhang, Edward Drasby, Rajeev Kumar, Thyagarajan Subramanian, Donna Stuppy Ford, David A Grimes, Diane Cote, Jennifer Conway, Andrew D Siderowf, Marian Leslie Evatt, Barbara Sommerfeld, Abraham N Lieberman, Michael S Okun, Ramon L Rodriguez, Stacy Merritt, Camille Louise Swartz, W R Wayne Martin, Pamela King, Natividad Stover, Stephanie Guthrie, Ray L Watts, Anwar Ahmed, Hubert H Fernandez, Adrienna Winters, Zoltan Mari, Ted M Dawson, Becky Dunlop, Andrew S Feigin, Barbara Shannon, Melissa Jill Nirenberg, Mattson Ogg, Samuel A Ellias, Cathi-Ann Thomas, Karen Frei, Ivan Bodis-Wollner, Sofya Glazman, Thomas Mayer, Robert A Hauser, Rajesh Pahwa, April Langhammer, Ranjit Ranawaya, Lorelei Derwent, Kapil D Sethi, Buff Farrow, Rajan Prakash, Irene Litvan, Annette Robinson, Alok Sahay, Maureen Gartner, Vanessa K Hinson, Samuel Markind, Melisa Pelikan, Joel S Perlmutter, Johanna Hartlein, Eric Molho, Sharon Evans, Charles H Adler, Amy Duffy, Marlene Lind, Lawrence Elmer, Kathy Davis, Julia Spears, Stephanie Wilson, Maureen A Leehey, Neal Hermanowicz, Shari Niswonger, Holly A Shill, Sanja Obradov, Alex Rajput, Marilyn Cowper, Stephanie Lessig, David Song, Deborah Fontaine, Cindy Zadikoff, Karen Williams, Karen A Blindauer, Jo Bergholte, Clara Schindler Propsom, Mark A Stacy, Joanne Field, Dragos Mihaila, Mark Chilton, Ergun Y Uc, Jeri Sieren, David K Simon, Lauren Kraics, Althea Silver, James T Boyd, Robert W Hamill, Christopher Ingvoldstad, Jennifer Young, Karen Thomas, Sandra K Kostyk, Joanne Wojcieszek, Ronald F Pfeiffer, Michel Panisset, Monica Beland, Stephen G Reich, Michelle Cines, Nancy Zappala, Jean Rivest, Richard Zweig, L Pepper Lumina, Colette Lynn Hilliard, Stephen Grill, Marye Kellermann, Paul Tuite, Susan Rolandelli, Un Jung Kang, Joan Young, Jayaraman Rao, Maureen M Cook, Lawrence Severt, Karyn Boyar
JAMA Neurol 2014 Mar;
PMID: 24664227 [PubMed - as supplied by publisher]


Direct Visualization of CHIP-Mediated Degradation of Alpha-Synuclein In Vivo: Implications for PD Therapeutics.
Hemi Dimant, Liya Zhu, Laura N Kibuuka, Zhanyun Fan, Bradley T Hyman, Pamela J McLean
PLoS One 2014 ; 9(3):e92098
PMID: 24664141 [PubMed - as supplied by publisher]


Clinician versus machine: Reliability and responsiveness of motor endpoints in Parkinson's disease.
Dustin A Heldman, Alberto J Espay, Peter A Lewitt, Joseph P Giuffrida
Parkinsonism Relat Disord 2014 Mar;
PMID: 24661464 [PubMed - as supplied by publisher]


Another face of placebo: The lessebo effect in Parkinson disease: Meta-analyses.
Tiago A Mestre, Prakesh Shah, Connie Marras, George Tomlinson, Anthony E Lang
Neurology 2014 Mar;
PMID: 24658930 [PubMed - as supplied by publisher]


Subthalamic nucleus involvement in executive functions with increased cognitive load: a subthalamic nucleus and anterior cingulate cortex depth recording study.
Stefania Rusnáková Aulická, Pavel Jurák, Jan Chládek, Pavel Daniel, Josef Halámek, Marek Balá?, Martina Bo?ková, Jan Chrastina, Ivan Rektor
J Neural Transm 2014 Mar;
PMID: 24658745 [PubMed - as supplied by publisher]


Improving Response Inhibition in Parkinson's Disease with Atomoxetine.
Zheng Ye, Ellemarije Altena, Cristina Nombela, Charlotte R Housden, Helen Maxwell, Timothy Rittman, Chelan Huddleston, Charlotte L Rae, Ralf Regenthal, Barbara J Sahakian, Roger A Barker, Trevor W Robbins, James B Rowe
Biol Psychiatry 2014 Feb;
PMID: 24655598 [PubMed - as supplied by publisher]


Optimised nanoformulation of bromocriptine for direct nose-to-brain delivery: biodistribution, pharmacokinetic and dopamine estimation by ultra-HPLC/mass spectrometry method.
Shadab Md, Shadabul Haque, Mohammad Fazil, Manish Kumar, Sanjula Baboota, Jasjeet K Sahni, Javed Ali
Expert Opin Drug Deliv 2014 Mar;
PMID: 24655115 [PubMed - as supplied by publisher]


Clinical studies with levodopa/carbidopa intestinal gel].
Péter Klivényi, László Vécsei
Ideggyogy Sz 2014 Jan; 67(1-2):5-8
PMID: 24654442 [PubMed - as supplied by publisher]


The Mechanistic Links Between Proteasome Activity, Aging and Age-related Diseases.
Isabel Saez, David Vilchez
Curr Genomics 2014 Feb; 15(1):38-51
PMID: 24653662 [PubMed - as supplied by publisher]


Molecular Effects of L-dopa Therapy in Parkinson's Disease.
Jolanta Dorszewska, Michal Prendecki, Margarita Lianeri, Wojciech Kozubski
Curr Genomics 2014 Feb; 15(1):11-7
PMID: 24653659 [PubMed - as supplied by publisher]


Investigation of morphometric variability of subthalamic nucleus, red nucleus, and substantia nigra in advanced Parkinson's disease patients using automatic segmentation and PCA-based analysis.
Yiming Xiao, Pierre Jannin, Tiziano D'Albis, Nicolas Guizard, Claire Haegelen, Florent Lalys, Marc Vérin, D Louis Collins
Hum Brain Mapp 2014 Feb;
PMID: 24652699 [PubMed - as supplied by publisher]


Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.
Mareike Caesar, Sandra Felk, Susanne Zach, Gunnar Brřnstad, Jan O Aasly, Thomas Gasser, Frank Gillardon
Glia 2014 Mar;
PMID: 24652679 [PubMed - as supplied by publisher]


Swallowing Outcomes Following Unilateral STN vs. GPi Surgery: A Retrospective Analysis.
Michelle S Troche, Alexandra E Brandimore, Kelly D Foote, Takashi Morishita, Dennis Chen, Karen W Hegland, Michael S Okun
Dysphagia 2014 Mar;
PMID: 24652582 [PubMed - as supplied by publisher]


Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing.
Lilach Soreq, Alessandro Guffanti, Nathan Salomonis, Alon Simchovitz, Zvi Israel, Hagai Bergman, Hermona Soreq
PLoS Comput Biol 2014 Mar; 10(3):e1003517
PMID: 24651478 [PubMed - as supplied by publisher]


Fulfilment of Patients´ Expectations Is the Ultimate Goal of Deep Brain Stimulation for Parkinson´s Disease.
Marwan Hariz
World Neurosurg 2014 Mar;
PMID: 24650489 [PubMed - as supplied by publisher]


Outcome following deep brain stimulation surgery of the subthalamic nucleus for Parkinson's disease: do we understand what's important to our patients?
Carole Joint, Tipu Aziz
World Neurosurg 2014 Mar;
PMID: 24650487 [PubMed - as supplied by publisher]


Wnt/?-catenin signaling is required to rescue midbrain dopaminergic progenitors and promote neurorepair in ageing mouse model of Parkinson's disease.
Francesca L'episcopo, Cataldo Tirolo, Nunzio Testa, Salvatore Caniglia, Maria Concetta Morale, Maria Francesca Serapide, Stefano Pluchino, Bianca Marchetti
Stem Cells 2014 Mar;
PMID: 24648001 [PubMed - as supplied by publisher]


Neuroscience: Tuning the brain.
Helen Shen
Nature 2014 Mar; 507(7492):290-2
PMID: 24646978 [PubMed - as supplied by publisher]


A Randomized Study of Rotigotine Dose Response on 'Off' Time in Advanced Parkinson's Disease.
Anthony P Nicholas, Rupam Borgohain, Pedro Chaná, Erwin Surmann, Emily L Thompson, Lars Bauer, John Whitesides, Lawrence W Elmer
J Parkinsons Dis 2014 Mar;
PMID: 24643203 [PubMed - as supplied by publisher]


Diagnostic Challenge of Pheochromocytoma in a Patient Receiving Levodopa for Parkinson's Disease.
Masanori Shimodaira, Tomohiro Niwa, Koji Nakajima, Mutsuhiro Kobayashi, Masanori Shimodaira, Tomohiro Niwa, Koji Nakajima, Mutsuhiro Kobayashi
Endocr Pract 2014 Mar; :1-14
PMID: 24641926 [PubMed - as supplied by publisher]


Subthalamic Nuclear Tissue Contrast in Inversion Recovery MRI Decreases with Age in Medically Refractory Parkinson's Disease.
Subhendra N Sarkar, Pooja R Sarkar, Efstathios Papavassiliou
J Neuroimaging 2014 Mar;
PMID: 24641526 [PubMed - as supplied by publisher]


NMDA antagonists as Parkinson's disease therapy: disseminating the evidence.
Zsófia Majláth, László Vécsei
Neurodegener Dis Manag 2014 Feb; 4(1):23-30
PMID: 24640976 [PubMed - as supplied by publisher]


The emerging role of nutrition in Parkinson's disease.
Stacey E Seidl, Jose A Santiago, Hope Bilyk, Judith A Potashkin
Front Aging Neurosci 2014 ; 6:36
PMID: 24639650 [PubMed - as supplied by publisher]


Changes in GABA and glutamate concentrations during memory tasks in patients with Parkinson's disease undergoing DBS surgery.
Robert J Buchanan, David P Darrow, Kevin T Meier, Jennifer Robinson, Dawn M Schiehser, David C Glahn, Zoltan Nadasdy
Front Hum Neurosci 2014 ; 8:81
PMID: 24639638 [PubMed - as supplied by publisher]


Symptomatic efficacy of rasagiline monotherapy in early Parkinson's disease: Post-hoc analyses from the ADAGIO trial.
Joseph Jankovic, Elijahu Berkovich, Eli Eyal, Eduardo Tolosa
Parkinsonism Relat Disord 2014 Mar;
PMID: 24637126 [PubMed - as supplied by publisher]


Parkinson's disease patients with subthalamic stimulation and carers judge quality of life differently.
Catharine J Lewis, Franziska Maier, Carsten Eggers, Esther A Pelzer, Mohammad Maarouf, Elena Moro, Mateusz Zurowski, Jens Kuhn, Christiane Woopen, Lars Timmermann
Parkinsonism Relat Disord 2014 Feb;
PMID: 24637125 [PubMed - as supplied by publisher]


Functional differentiation of midbrain neurons from human cord blood-derived induced pluripotent stem cells.
Nancy Stanslowsky, Alexandra Haase, Ulrich Martin, Maximilian Naujock, Andreas Leffler, Reinhard Dengler, Florian Wegner
Stem Cell Res Ther 2014 Mar; 5(2):35
PMID: 24636737 [PubMed - as supplied by publisher]


Sequence Variants in SLC6A3, DRD2, and BDNF Genes and Time to Levodopa-Induced Dyskinesias in Parkinson's Disease.
Natalie Kaplan, Aya Vituri, Amos D Korczyn, Oren S Cohen, Rivka Inzelberg, Gilad Yahalom, Evgenia Kozlova, Roni Milgrom, Yael Laitman, Eitan Friedman, Saharon Rosset, Sharon Hassin-Baer
J Mol Neurosci 2014 Mar;
PMID: 24633632 [PubMed - as supplied by publisher]


Comparing clinical features of young onset, middle onset and late onset Parkinson's disease.
Raja Mehanna, Suzanne Moore, J Gabriel Hou, Aliya I Sarwar, Eugene C Lai
Parkinsonism Relat Disord 2014 Feb;
PMID: 24631501 [PubMed - as supplied by publisher]


Low-frequency repetitive transcranial magnetic stimulation for dyskinesia and motor performance in Parkinson's disease.
Sevgi Say?n, Raif Cakmur, Görsev G Yener, Erdem Yaka, Burcu U?urel, Fatma Uzunel
J Clin Neurosci 2014 Mar;
PMID: 24631324 [PubMed - as supplied by publisher]