Spotlight on Research

Roy N. Alcalay, M.D.
"Why do some people who carry genetic mutations associated with Parkinson’s disease (PD) never develop PD while others do?" asks Roy N. Alcalay, M.D., a postdoctoral fellow at the Center for Parkinson’s Disease and Other Movement Disorders...
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Deep brain stimulation for Parkinson's disease: Australian referral guidelines.
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J Clin Neurosci 2009 Aug; 16(8):1001-8
Authors: Paul Silberstein, Richard G Bittar, Richard Boyle, Raymond Cook, Terry Coyne, Dudley O'Sullivan, Malcolm Pell, Richard Peppard, Julian Rodrigues, Peter Silburn, Rick Stell, Peter Watson,
North Shore Private Hospital, Sydney, New South Wales, Australia.
The advent of deep brain stimulation (DBS) has been an important advance in the treatment of Parkinson's disease (PD). DBS may be employed in the management of medication-refractory tremor or treatment-related motor complications, and may benefit between 4.5% and 20% of patients at some stage of their disease course. In Australia, patients with PD are reviewed by specialised DBS teams who assess the likely benefits and risks associated with DBS for each individual. The aim of these guidelines is to assist neurologists and general physicians identify patients who may benefit from referral to a DBS team. Common indications for referral are motor fluctuations and/or dyskinesias that are not adequately controlled with optimised medical therapy, medication-refractory tremor, and intolerance to medical therapy. Early referral for consideration of DBS is recommended as soon as optimised medical therapy fails to offer satisfactory motor control.
PMID: 19596113 [PubMed - as supplied by publisher]










