Treatments/Pipeline

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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The cortical and striatal gene expression profile of 100?hz electroacupuncture treatment in 6-hydroxydopamine-induced Parkinson's disease model.
Li-Rong Huo, Xi-Bin Liang, Bo Li, Jian-Tao Liang, Yi He, Yan-Jun Jia, Jun Jia, Xiao-Li Gong, Fen Yu, Xiao-Min Wang
Evid Based Complement Alternat Med 2012 ; 2012:908439
PMID: Object id #234122319547 [PubMed - as supplied by publisher]

Pardoprunox as adjunct therapy to levodopa in patients with Parkinson's disease experiencing motor fluctuations: Results of a double-blind, randomized, placebo-controlled, trial.
O Rascol, J Bronzova, R A Hauser, A E Lang, C Sampaio, A Theeuwes, S V van de Witte
Parkinsonism Relat Disord 2012 Feb;
PMID: Object id #238422316635 [PubMed - as supplied by publisher]

Postmortem observation of collagenous lead tip region fibrosis as a rare complication of DBS.
Vinata Vedam-Mai, Anthony Yachnis, Michael Ullman, Saman P Javedan, Michael S Okun
Mov Disord 2012 Feb;
PMID: Object id #241522314706 [PubMed - as supplied by publisher]

Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells.
Houbo Jiang, Yong Ren, Eunice Y Yuen, Ping Zhong, Mahboobe Ghaedi, Zhixing Hu, Gissou Azabdaftari, Kazuhiro Nakaso, Zhen Yan, Jian Feng
Nat Commun 2012 ; 3:668
PMID: Object id #243922314364 [PubMed - as supplied by publisher]

Cellular models to investigate biochemical pathways in Parkinson's disease.
Tiziana Alberio, Leonardo Lopiano, Mauro Fasano
FEBS J 2012 Feb;
PMID: Object id #246622314200 [PubMed - as supplied by publisher]

Clinical Inquiry: Which drugs work best for early Parkinson's disease?
Liza Jain, Rebecca Benko, Sarah Safranek
J Fam Pract 2012 Feb; 61(2):106-8
PMID: Object id #246922312616 [PubMed - as supplied by publisher]

Inhibition of monoamine oxidase by selected C6-substituted chromone derivatives.
Lesetja J Legoabe, Anél Petzer, Jacobus P Petzer
Eur J Med Chem 2012 Jan;
PMID: Object id #251322309913 [PubMed - as supplied by publisher]

Dopamine release via the vacuolar ATPase V0 sector c-subunit, confirmed in N18 neuroblastoma cells, results in behavioral recovery in hemiparkinsonian mice.
Duo Jin, Shin-Ichi Muramatsu, Nobuaki Shimizu, Shigeru Yokoyama, Hirokazu Hirai, Kiyofumi Yamada, Hong-Xiang Liu, Chiharu Higashida, Minako Hashii, Akihiko Higashida, Masahide Asano, Shoji Ohkuma, Haruhiro Higashida
Neurochem Int 2012 Jan;
PMID: Object id #133022265874 [PubMed - as supplied by publisher]

Design and synthesis of 8-substituted benzamido-phenylxanthine derivatives as MAO-B inhibitors.
Bo Song, Tong Xiao, Xiaolu Qi, Ling-Na Li, Kuiyou Qin, Siyun Nian, Guo-Xin Hu, Yinfei Yu, Guang Liang, Faqing Ye
Bioorg Med Chem Lett 2012 Feb; 22(4):1739-42
PMID: Object id #113422257893 [PubMed - as supplied by publisher]

Treatment Options for Tauopathies.
Tarik Karakaya, Fabian Fußer, David Prvulovic, Harald Hampel
Curr Treat Options Neurol 2012 Feb;
PMID: Object id #253622307450 [PubMed - as supplied by publisher]

Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic?
Filippo Caraci, Giuseppe Battaglia, Maria Angela Sortino, Simona Spampinato, Gemma Molinaro, Agata Copani, Ferdinando Nicoletti, Valeria Bruno
Neurochem Int 2012 Jan;
PMID: Object id #233622306345 [PubMed - as supplied by publisher]

Effects of natural antioxidants in neurodegenerative disease.
Sonia Luz Albarracin, Ben Stab, Zulma Casas, Jhon Jairo Sutachan, Ismael Samudio, Janneth Gonzalez, Luis Gonzalo, Francisco Capani, Ludis Morales, George E Barreto
Nutr Neurosci 2012 Jan; 15(1):1-9
PMID: Object id #230722305647 [PubMed - as supplied by publisher]

Clinical translation of stem cells in neurodegenerative disorders.
Olle Lindvall, Roger A Barker, Oliver Brüstle, Ole Isacson, Clive N Svendsen
Cell Stem Cell 2012 Feb; 10(2):151-5
PMID: Object id #227822305565 [PubMed - as supplied by publisher]

Transcient improvement of extrapyramidal syndrome after general anaesthesia.
C Poivert, J-P Graftieaux, P Gomis, B Scherpereel, J-M Malinovsky
Ann Fr Anesth Reanim 2012 Feb;
PMID: Object id #225622305400 [PubMed - as supplied by publisher]

Rebound symptoms following battery depletion in the NIH OCD DBS cohort: clinical and reimbursement issues.
A K Vora, H Ward, K D Foote, W K Goodman, M S Okun
Brain Stimul 2011 Nov;
PMID: Object id #223022305344 [PubMed - as supplied by publisher]

Levodopa influences striatal activity but does not affect cortical hyper-activity in Parkinson's disease.
K Martinu, C Degroot, C Madjar, A P Strafella, O Monchi
Eur J Neurosci 2012 Feb;
PMID: Object id #220322304628 [PubMed - as supplied by publisher]

Indirect comparisons of Adverse Events and Dropout Rates in Early Parkinson's Disease Trials of Pramipexole, Ropinirole, and Rasagiline.
Francisco J Zagmutt, Marcy Tarrants
Int J Neurosci 2012 Feb;
PMID: Object id #217922304415 [PubMed - as supplied by publisher]

Discovery of MAO-B inhibitors - present status and future directions. Part I: Oxygen heterocycles and analogues.
Aliuska Morales Helguera, Gisselle Pérez-Machado, M Natalia D S Cordeiro, Fernanda Borges
Mini Rev Med Chem 2012 Feb;
PMID: Object id #214422303972 [PubMed - as supplied by publisher]

Neurology].
J N Chabwine, A R Rossetti, L Hirt, T Kuntzer, M Schluep, P Michel, J F Démonet, R A du Pasquier, F G Vingerhoets
Rev Med Suisse 2012 Jan; 8(323):46-50
PMID: Object id #213122303740 [PubMed - as supplied by publisher]

Lipopolysaccharide-induced nigral inflammation leads to increased IL-1? tissue content and expression of astrocytic glial cell line-derived neurotrophic factor.
Mahmoud M Iravani, Mona Sadeghian, Clement C M Leung, Peter Jenner, Sarah Rose
Neurosci Lett 2012 Jan;
PMID: Object id #168522281445 [PubMed - as supplied by publisher]

Deep brain stimulation: What can patients expect from it?
Andre Machado, Hubert H Fernandez, Milind Deogaonkar
Cleve Clin J Med 2012 Feb; 79(2):113-20
PMID: Object id #208322301561 [PubMed - as supplied by publisher]

Interactions between the cannabinoid and dopaminergic systems: Evidence from animal studies.
Marie-Anne El Khoury, Victor Gorgievski, Larissa Moutsimilli, Bruno Giros, Eleni T Tzavara
Prog Neuropsychopharmacol Biol Psychiatry 2012 Jan;
PMID: Object id #207722300746 [PubMed - as supplied by publisher]

Disease Progress and Response to Treatment as Predictors of Survival, Disability, Cognitive Impairment, and Depression in Parkinson's Disease.
Thuy C Vu, John G Nutt, Nicholas Hg Holford
Br J Clin Pharmacol 2012 Feb;
PMID: Object id #205622300470 [PubMed - as supplied by publisher]

Transaxillary Subpectoral Implantation of Implantable Pulse Generator for Deep Brain Stimulation.
Byung-Chul Son, Soo-Hyung Han, Yoon-Suk Choi, Hyung-Suk Kim, Min-Cheol Kim, Seung-Ho Yang, Sang-Won Lee
Neuromodulation 2012 Feb;
PMID: Object id #203422300254 [PubMed - as supplied by publisher]

Patient considerations in early management of Parkinson's disease: focus on extended-release pramipexole.
Fatai Kunle Salawu
Patient Prefer Adherence 2012 ; 6:49-54
PMID: Object id #200822298943 [PubMed - as supplied by publisher]

Knotting of Percutaneous Endoscopic Jejunostomy Feeding Tubes in Two Patients with Parkinson's Disease and Continuous Duodopa® treatment.
E Krones, G Zollner, W Petritsch
Z Gastroenterol 2012 Feb; 50(2):213-216
PMID: Object id #198822298101 [PubMed - as supplied by publisher]

Elevated Pontine and Putamenal GABA Levels in Mild-Moderate Parkinson Disease Detected by 7 Tesla Proton MRS.
Uzay E Emir, Paul J Tuite, Gülin Oz
PLoS One 2012 ; 7(1):e30918
PMID: Object id #196522295119 [PubMed - as supplied by publisher]

Effects of STN and GPi Deep Brain Stimulation on Impulse Control Disorders and Dopamine Dysregulation Syndrome.
Sarah J Moum, Catherine C Price, Natlada Limotai, Genko Oyama, Herbert Ward, Charles Jacobson, Kelly D Foote, Michael S Okun
PLoS One 2012 ; 7(1):e29768
PMID: Object id #193822295068 [PubMed - as supplied by publisher]

Pedunculopontine nucleus deep brain stimulation in Parkinson's disease.
Tomasz Tykocki, Tomasz Mandat, Pawe? Nauman
Arch Med Sci 2011 Aug; 7(4):555-64
PMID: Object id #190922291786 [PubMed - as supplied by publisher]

Deep brain stimulation for movement disorders.
Gilberto Pizzolato, Tomasz Mandat
Front Integr Neurosci 2012 ; 6:2
PMID: Object id #186622291623 [PubMed - as supplied by publisher]

Rivastigmine as alternative treatment for refractory REM behavior disorder in Parkinson's disease.
Raffaella Di Giacopo, Alfonso Fasano, Davide Quaranta, Giacomo Della Marca, Francesco Bove, Anna Rita Bentivoglio
Mov Disord 2012 Jan;
PMID: Object id #183822290743 [PubMed - as supplied by publisher]

IPX066: a novel carbidopa-levodopa extended-release formulation.
Robert A Hauser
Expert Rev Neurother 2012 Feb; 12(2):133-40
PMID: Object id #183422288668 [PubMed - as supplied by publisher]

Optimizing levodopa therapy to treat wearing-off symptoms in Parkinson's disease: focus on levodopa/carbidopa/entacapone.
Heinz Reichmann, Murat Emre
Expert Rev Neurother 2012 Feb; 12(2):119-31
PMID: Object id #178722288667 [PubMed - as supplied by publisher]

No clinically significant valvular regurgitation in long term cabergoline treatment for prolactinoma.
Irene Halperin, Javier Aller, César Varela, Mireia Mora, Ainhoa Abad, Ada Doltra, Alicia Estrella Santos, Esther Batista, Pablo García-Pavía, Marta Sitges, Jesús G Mirelis, Tomás Lucas, Manel Puig-Domingo
Clin Endocrinol (Oxf) 2012 Jan;
PMID: Object id #179622288503 [PubMed - as supplied by publisher]

Brain-derived neurotrophic factor-mediated effects on mitochondrial respiratory coupling and neuroprotection share the same molecular signalling pathways.
Anthony Markham, Ian Cameron, Rasneer Bains, Paul Franklin, Janos P Kiss, Leslie Schwendimann, Pierre Gressens, Michael Spedding
Eur J Neurosci 2012 Feb; 35(3):366-374
PMID: Object id #176222288477 [PubMed - as supplied by publisher]

Progression of Motor and Non-Motor Features of Parkinson's Disease and Their Response to Treatment.
Thuy C Vu, John G Nutt, Nicholas Hg Holford
Br J Clin Pharmacol 2012 Jan;
PMID: Object id #173822283961 [PubMed - as supplied by publisher]

A new D(2) dopamine receptor agonist allosterically modulates A(2A) adenosine receptor signalling by interacting with the A(2A)/D(2) receptor heteromer.
Maria Letizia Trincavelli, Simona Daniele, Elisabetta Orlandini, Gemma Navarro, Vicent Casadó, Chiara Giacomelli, Susanna Nencetti, Elisa Nuti, Marco Macchia, Harald Huebner, Peter Gmeiner, Armando Rossello, Carmen Lluís, Claudia Martini
Cell Signal 2012 Apr; 24(4):951-60
PMID: Object id #21822230688 [PubMed - as supplied by publisher]

Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Anti-Diabetes Drugs.
Claudia Binda, Milagros Aldeco, Werner J Geldenhuys, Marcello Tortorici, Andrea Mattevi, Dale E Edmondson
ACS Med Chem Lett 2011 Oct; 3(1):39-42
PMID: Object id #169222282722 [PubMed - as supplied by publisher]

Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of ?-synucleinopathy.
Kiren Ubhi, Chandra Inglis, Michael Mante, Christina Patrick, Anthony Adame, Brian Spencer, Edward Rockenstein, Verena May, Juergen Winkler, Eliezer Masliah
Exp Neurol 2012 Jan;
PMID: Object id #165022281106 [PubMed - as supplied by publisher]

A scaffold hopping approach to identify novel monoamine oxidase B inhibitors.
Werner J Geldenhuys, Max O Funk, Cornelis J Van der Schyf, Richard T Carroll
Bioorg Med Chem Lett 2012 Feb; 22(3):1380-3
PMID: Object id #4822225638 [PubMed - as supplied by publisher]

Current steering to activate targeted neural pathways during deep brain stimulation of the subthalamic region.
Ashutosh Chaturvedi, Thomas J Foutz, Cameron C McIntyre
Brain Stimul 2011 Jun;
PMID: Object id #163122277548 [PubMed - as supplied by publisher]

Selective degradation of expanded polyglutamine proteins by their specific recognition with QBP1.
Yoshitaka Nagai, Nobuyuki Nukina
Rinsho Shinkeigaku 2011 Nov; 51(11):1108-10
PMID: Object id #160322277499 [PubMed - as supplied by publisher]

Drug-induced parkinsonism in the elderly: incidence, management and prevention.
José Luis López-Sendón, María Angeles Mena, Justo García de Yébenes
Drugs Aging 2012 Feb; 29(2):105-18
PMID: Object id #74222250585 [PubMed - as supplied by publisher]

The effects of DBS patterns on basal ganglia activity and thalamic relay : A computational study.
Rahul Agarwal, Sridevi V Sarma
J Comput Neurosci 2012 Jan;
PMID: Object id #45622237601 [PubMed - as supplied by publisher]

Nonmotor outcomes in Parkinson's disease: is deep brain stimulation better than dopamine replacement therapy?
Rupam Borgohain, Rukmini Mridula Kandadai, Afshan Jabeen, Meena A Kannikannan
Ther Adv Neurol Disord 2012 Jan; 5(1):23-41
PMID: Object id #158522276074 [PubMed - as supplied by publisher]

Advances in the Treatment of Neurodegenerative Disorders Employing Nanoparticles.
Carlos Spuch, Ortolano Saida, Carmen Navarro
Recent Pat Drug Deliv Formul 2012 Jan;
PMID: Object id #156122272933 [PubMed - as supplied by publisher]

Evaluation of the Neurotoxic/Neuroprotective Role of Organoselenides Using Differentiated Human Neuroblastoma SH-SY5Y Cell Line Challenged with 6-Hydroxydopamine.
Fernanda Martins Lopes, Giovana Ferreira Londero, Liana Marengo de Medeiros, Leonardo Lisbôa da Motta, Guilherme Antônio Behr, Valeska Aguiar de Oliveira, Mohammad Ibrahim, José Cláudio Fonseca Moreira, Lisiane de Oliveira Porciúncula, João Batista Teixeira da Rocha, Fábio Klamt
Neurotox Res 2012 Jan;
PMID: Object id #153622271527 [PubMed - as supplied by publisher]

Targeting the brain: considerations in 332 consecutive patients treated by deep brain stimulation (DBS) for severe neurological diseases.
Angelo Franzini, Roberto Cordella, Giuseppe Messina, Carlo Efisio Marras, Luigi Michele Romito, Alberto Albanese, Michele Rizzi, Nardo Nardocci, Giovanna Zorzi, Edvin Zekaj, Flavio Villani, Massimo Leone, Orsola Gambini, Giovanni Broggi
Neurol Sci 2012 Jan;
PMID: Object id #148522271259 [PubMed - as supplied by publisher]

Polyneuropathy while on duodenal levodopa infusion in Parkinson's disease patients: we must be alert.
Diego Santos-García, Raúl de la Fuente-Fernández, Francesc Valldeoriola, Antonio Palasí, Fátima Carrillo, Mónica Grande, Pablo Mir, Oriol De Fabregues, Jordi Casanova
J Neurol 2012 Jan;
PMID: Object id #146822270132 [PubMed - as supplied by publisher]

A Mechanistic Study of Proteasome Inhibition-Induced Iron Misregulation in Dopamine Neuron Degeneration.
Xu-Ping Li, Wen-Jie Xie, Zhen Zhang, Sagar Kansara, Joseph Jankovic, Wei-Dong Le
Neurosignals 2012 Jan;
PMID: Object id #143222269801 [PubMed - as supplied by publisher]

Genetics of Parkinson's disease.
Kishore R Kumar, Ana Djarmati-Westenberger, Anne Grünewald
Semin Neurol 2011 Nov; 31(5):433-40
PMID: Object id #140822266881 [PubMed - as supplied by publisher]

Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: similar improvements in saccadic and manual responses.
Chrystalina A Antoniades, Roger H S Carpenter, Yasin Temel
Neuroreport 2012 Feb; 23(3):179-83
PMID: Object id #138322266732 [PubMed - as supplied by publisher]

Dementia is associated with Insulin Resistance in patients with Parkinson's Disease.
Domenico Bosco, Massimiliano Plastino, Dario Cristiano, Carmela Colica, Caterina Ermio, Matteo De Bartolo, Pasquale Mungari, Giulia Fonte, Domenico Consoli, Arturo Consoli, Antonietta Fava
J Neurol Sci 2012 Jan;
PMID: Object id #136522265943 [PubMed - as supplied by publisher]

Verbal Fluency in Patients Receiving Bilateral versus Left-Sided Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson's Disease.
Rickard L Sjöberg, Elin Lidman, Björn Häggström, Marwan I Hariz, Jan Linder, Anna Fredricks, Patric Blomstedt
J Int Neuropsychol Soc 2012 Jan; :1-6
PMID: Object id #128522264411 [PubMed - as supplied by publisher]

Deep brain stimulation in Parkinson's disease: opening up the race towards better technology.
Jens Volkmann
Lancet Neurol 2012 Feb; 11(2):121-3
PMID: Object id #62722239916 [PubMed - as supplied by publisher]

Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial.
Michael S Okun, Bruno V Gallo, George Mandybur, Jonathan Jagid, Kelly D Foote, Fredy J Revilla, Ron Alterman, Joseph Jankovic, Richard Simpson, Fred Junn, Leo Verhagen, Jeff E Arle, Blair Ford, Robert R Goodman, R Malcolm Stewart, Stacy Horn, Gordon H Baltuch, Brian H Kopell, Frederick Marshall, Delea Peichel, Rajesh Pahwa, Kelly E Lyons, Alexander I Tröster, Jerrold L Vitek, Michele Tagliati,
Lancet Neurol 2012 Feb; 11(2):140-149
PMID: Object id #61122239915 [PubMed - as supplied by publisher]

Improvement of Neural Stem Cell Survival in Collagen Hydrogels by Incorporating Laminin-Derived Cell Adhesive Polypeptides.
Tadashi Nakaji-Hirabayashi, Koichi Kato, Hiroo Iwata
Bioconjug Chem 2012 Jan;
PMID: Object id #18122229651 [PubMed - as supplied by publisher]

GDNF Is Predominantly Expressed in the PV+ Neostriatal Interneuronal Ensemble in Normal Mouse and after Injury of the Nigrostriatal Pathway.
María Hidalgo-Figueroa, Sonia Bonilla, Francisco Gutiérrez, Alberto Pascual, José López-Barneo
J Neurosci 2012 Jan; 32(3):864-72
PMID: Object id #126922262884 [PubMed - as supplied by publisher]

Paradoxical worsening of gait with levodopa in Parkinson disease.
Robert Chen
Neurology 2012 Jan;
PMID: Object id #124722262745 [PubMed - as supplied by publisher]

"On" state freezing of gait in Parkinson disease: A paradoxical levodopa-induced complication.
A J Espay, A Fasano, B F L van Nuenen, M M Payne, A H Snijders, B R Bloem
Neurology 2012 Jan;
PMID: Object id #122622262741 [PubMed - as supplied by publisher]

Effects of bushenhuoxue granules on sleep quality in Parkinson's patients].
Min Li, Ming-Hui Yang, Shao-Dan Li, Yi Liu
Zhong Yao Cai 2011 Sep; 34(9):1473-7
PMID: Object id #119922260015 [PubMed - as supplied by publisher]

Interventions for fatigue and weight loss in adults with advanced progressive illness.
Cathy Payne, Philip J Wiffen, Suzanne Martin
Cochrane Database Syst Rev 2012 ; 1:CD008427
PMID: Object id #117922258985 [PubMed - as supplied by publisher]

Pramipexole-Induced Increased Probabilistic Discounting: Comparison Between a Rodent Model of Parkinson's Disease and Controls.
Sandra L Rokosik, T Celeste Napier
Neuropsychopharmacology 2012 Jan;
PMID: Object id #115722257895 [PubMed - as supplied by publisher]

Characterization of subcortical structures during deep brain stimulation utilizing support vector machines.
P Guillen, F Martinez-de-Pison, R Sanchez, M Argaez, L Velazquez
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:7949-52
PMID: Object id #110222256184 [PubMed - as supplied by publisher]

Effect of subthalamic nucleus interconnectivity at deep brain stimulation onset and offset: A simulation study.
Guiyeom Kang, Madeleine M Lowery
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:7107-10
PMID: Object id #108022255976 [PubMed - as supplied by publisher]

Application of non-linear control theory to a model of deep brain stimulation.
Clare M Davidson, Madeleine M Lowery, Annraoi M de Paor
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:6785-8
PMID: Object id #105822255896 [PubMed - as supplied by publisher]

On automated assessment of Levodopa-induced dyskinesia in Parkinson's disease.
Markos G Tsipouras, Alexandros T Tzallas, Dimitrios I Fotiadis, Spyridon Konitsiotis
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:2679-82
PMID: Object id #103922254893 [PubMed - as supplied by publisher]

Closing the loop for deep brain stimulation implants enables personalized healthcare for Parkinson's disease patients.
Wolfgang Eberle, Julien Penders, Refet Firat Yazicioglu
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:1556-8
PMID: Object id #100822254618 [PubMed - as supplied by publisher]

Emerging techniques for elucidating mechanism of action of deep brain stimulation.
Kendall H Lee, Su-Youne Chang, Dong-Pyo Jang, Inyong Kim, Stephan Goerss, Jamie Van Gompel, Paul Min, Kanika Arora, Michael Marsh, Sun Chul Hwang, Christopher J Kimble, Paul Garris, Charles Blaha, Kevin E Bennet
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:677-80
PMID: Object id #99522254400 [PubMed - as supplied by publisher]

Improving postural stability via computational modeling approach to deep brain stimulation programming.
Cameron C McIntyre, Sarah J Richardson, Anneke M Frankemolle, Georgeta Varga, Angela M Noecker, Jay L Alberts
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:675-6
PMID: Object id #96322254399 [PubMed - as supplied by publisher]

The translational value of the MPTP non-human primate model of Parkinsonism for deep brain stimulation research.
Peter A Tass, Li Qin, Christian Hauptmann, Sandra Dovero, Erwan Bezard, Thomas Boraud, Wassilios G Meissner
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:663-6
PMID: Object id #94022254396 [PubMed - as supplied by publisher]

Development of an implantable microstimulation system for chronic DBS in rodents.
Raik Paulat, Wassilios Meissner, Rudolf Morgenstern, Andreas Kupsch, Daniel Harnack
Conf Proc IEEE Eng Med Biol Soc 2011 Aug; 2011:660-2
PMID: Object id #90522254395 [PubMed - as supplied by publisher]

Prospect of cell therapy for Parkinson's disease.
Jeanne Adiwinata Pawitan
Anat Cell Biol 2011 Dec; 44(4):256-64
PMID: Object id #89122254154 [PubMed - as supplied by publisher]

The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease.
Edward C Lauterbach, Leonardo F Fontenelle, Antonio L Teixeira
Parkinsons Dis 2012 ; 2012:753548
PMID: Object id #86722254151 [PubMed - as supplied by publisher]

Critical aspects of clinical trial design for novel cell and gene therapies.
Zinovia Kefalopoulou, Iciar Aviles-Olmos, Thomas Foltynie
Parkinsons Dis 2011 ; 2011:804041
PMID: Object id #84122254150 [PubMed - as supplied by publisher]

Stem cell therapy for cerebral ischemia: from basic science to clinical applications.
Koji Abe, Toru Yamashita, Shunya Takizawa, Satoshi Kuroda, Hiroyuki Kinouchi, Nobutaka Kawahara
J Cereb Blood Flow Metab 2012 Jan;
PMID: Object id #81922252239 [PubMed - as supplied by publisher]

Deep brain stimulation and ethics: perspectives from a multisite qualitative study of canadian neurosurgical centers.
Emily Bell, Bruce Maxwell, Mary Pat McAndrews, Abbas Sadikot, Eric Racine
World Neurosurg 2011 Dec; 76(6):537-47
PMID: Object id #76422251502 [PubMed - as supplied by publisher]

Compositions and methods for treatment of Parkinson's disease: a patent evaluation of WO2011/102847A1.
Valerio Chiurchiù, Mauro Maccarrone, Antonio Orlacchio
Expert Opin Ther Pat 2012 Jan;
PMID: Object id #73922251081 [PubMed - as supplied by publisher]

Serotonergic involvement in levodopa-induced dyskinesias in Parkinson's disease.
Perdita A Cheshire, David R Williams
J Clin Neurosci 2012 Jan;
PMID: Object id #72322249009 [PubMed - as supplied by publisher]

Duodenal levodopa/carbidopa infusion therapy in patients with advanced Parkinson's disease leads to improvement in caregivers' stress and burden.
D Santos-García, M J Añón, L Fuster-Sanjurjo, R de la Fuente-Fernández
Eur J Neurol 2012 Jan;
PMID: Object id #69822248261 [PubMed - as supplied by publisher]

Law and ethics of deep brain stimulation.
Björn Schmitz-Luhn, Christian Katzenmeier, Christiane Woopen
Int J Law Psychiatry 2012 Jan;
PMID: Object id #67422244083 [PubMed - as supplied by publisher]

Dose-dependent impulse control disorders in piribedil overdose.
Juan Carlos Giugni, Lorena Tschopp, Victoria Escalante, Federico Micheli
Clin Neuropharmacol 2012 Jan; 35(1):49-50
PMID: Object id #65322240861 [PubMed - as supplied by publisher]

Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption.
S Barak, S Ahmadiantehrani, V Kharazia, D Ron
Transl Psychiatry 2011 Dec; 2011(1)
PMID: Object id #53822238721 [PubMed - as supplied by publisher]

L-DOPA Impairs Proteasome Activity in Parkinsonism through D1 Dopamine Receptor.
Amandine Berthet, Erwan Bezard, Gregory Porras, Stefania Fasano, Pedro Barroso-Chinea, Benjamin Dehay, Audrey Martinez, Marie-Laure Thiolat, Marika Nosten-Bertrand, Bruno Giros, Jérôme Baufreton, Qin Li, Bertrand Bloch, Marie-Laure Martin-Negrier
J Neurosci 2012 Jan; 32(2):681-91
PMID: Object id #54322238104 [PubMed - as supplied by publisher]

Apathy in parkinson's disease: Diagnostic and etiological dilemmas.
Sergio E Starkstein
Mov Disord 2012 Jan;
PMID: Object id #50922237755 [PubMed - as supplied by publisher]

The Effect of Surface Electrical Stimulation on Swallowing in Dysphagic Parkinson Patients.
Laura W J Baijens, Renée Speyer, Valeria Lima Passos, Walmari Pilz, Nel Roodenburg, Père Clavé
Dysphagia 2012 Jan;
PMID: Object id #47722237722 [PubMed - as supplied by publisher]

Regulation of Acid-Base Transporters by Reactive Oxygen Species Following Mitochondrial Fragmentation.
David Johnson, Erik Allman, Keith Nehrke
Am J Physiol Cell Physiol 2012 Jan;
PMID: Object id #43622237403 [PubMed - as supplied by publisher]

Benserazide dosing regimen affects the response to L-3,4-dihydroxyphenylalanine in the 6-hydroxydopamine-lesioned rat.
Kayhan A Tayarani-Binazir, Michael J Jackson, Isobel Strang, Mark Jairaj, Sarah Rose, Peter Jenner
Behav Pharmacol 2012 Jan;
PMID: Object id #41422236652 [PubMed - as supplied by publisher]

Assessment of appropriate medication administration for hospitalized patients with Parkinson's disease.
Jyhgong Gabriel Hou, Laura J Wu, Suzanne Moore, Constance Ward, Michele York, Farah Atassi, Linda Fincher, Naomi Nelson, Aliya Sarwar, Eugene C Lai
Parkinsonism Relat Disord 2012 Jan;
PMID: Object id #38322236581 [PubMed - as supplied by publisher]

Comprehensive in vivo Mapping of the Human Basal Ganglia and Thalamic Connectome in Individuals Using 7T MRI.
Christophe Lenglet, Aviva Abosch, Essa Yacoub, Federico De Martino, Guillermo Sapiro, Noam Harel
PLoS One 2012 ; 7(1):e29153
PMID: Object id #35622235267 [PubMed - as supplied by publisher]

Efficacy and Safety of Deep Brain Stimulation as an Adjunct to Pharmacotherapy for the Treatment of Parkinson Disease (February).
Alok Sharma, Kaylene Szeto, Alicia R Desilets
Ann Pharmacother 2012 Jan;
PMID: Object id #32922234991 [PubMed - as supplied by publisher]

Targeting the PedunculopontineNucleus: ANew Neurophysiological Method Based on Somatosensory Evoked Potentials to Calculate the Distance of DBS Lead from the Obex.
Angeloinsola, Massimiliano Valeriani, Paolo Mazzone
Neurosurgery 2012 Jan;
PMID: Object id #30722233920 [PubMed - as supplied by publisher]

A prolyl oligopeptidase inhibitor, KYP-2047, reduces ?-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.
T T Myöhänen, M J Hannula, R Van Elzen, M Gerard, P Van Der Veken, J A García-Horsman, V Baekelandt, P T Männistö, A M Lambeir
Br J Pharmacol 2012 Jan;
PMID: Object id #28522233220 [PubMed - as supplied by publisher]

REM sleep behavior disorder in Japanese patients with Parkinson's disease: a multicenter study using the REM sleep behavior disorder screening questionnaire.
Yoshihiro Nihei, Kazushi Takahashi, Atsuo Koto, Ban Mihara, Yoko Morita, Kazuo Isozumi, Kouichi Ohta, Kazuhiro Muramatsu, Jun Gotoh, Keiji Yamaguchi, Yutaka Tomita, Hideki Sato, Morinobu Seki, Satoko Iwasawa, Norihiro Suzuki
J Neurol 2012 Jan;
PMID: Object id #25722231870 [PubMed - as supplied by publisher]

The history of Parkinson's disease: early clinical descriptions and neurological therapies.
Christopher G Goetz
Cold Spring Harb Perspect Med 2011 Sep; 1(1):a008862
PMID: Object id #15322229124 [PubMed - as supplied by publisher]

Autopsy confirmed multiple system atrophy cases: Mayo experience and role of autonomic function tests.
Valeria Iodice, Axel Lipp, J Eric Ahlskog, Paola Sandroni, Robert D Fealey, Joseph E Parisi, Joseph Y Matsumoto, Eduardo E Benarroch, Kurt Kimpinski, Wolfgang Singer, Tonette L Gehrking, Jade A Gehrking, David M Sletten, Ann M Schmeichel, James H Bower, Sid Gilman, Juan Figueroa, Phillip A Low
J Neurol Neurosurg Psychiatry 2012 Jan;
PMID: Object id #14022228725 [PubMed - as supplied by publisher]

What predicts cognitive decline in de novo Parkinson's disease?
Dario Arnaldi, Claudio Campus, Michela Ferrara, Francesco Famà, Agnese Picco, Fabrizio De Carli, Jennifer Accardo, Andrea Brugnolo, Gianmario Sambuceti, Silvia Morbelli, Flavio Nobili
Neurobiol Aging 2012 Jan;
PMID: Object id #10422226489 [PubMed - as supplied by publisher]

Neuroprotection provided by dietary restriction in rats is further enhanced by reducing glucocortocoids.
Guang Qiu, Edward L Spangler, Ruiqian Wan, Marshall Miller, Mark P Mattson, Kwok-Fai So, Rafael de Cabo, Sige Zou, Donald K Ingram
Neurobiol Aging 2012 Jan;
PMID: Object id #1722226488 [PubMed - as supplied by publisher]

Selective IGT decision-making impairment in a patient with juvenile Parkinson's disease and pathological gambling: A role for dopaminergic therapy?
Riccardo Pignatti, Andrea Brioschi, Alessandro Mauro, Laura Zamarian, Johanna Wenter, Carlo Semenza
Neurocase 2012 Jan;
PMID: Object id #7522224448 [PubMed - as supplied by publisher]

Perspectives regarding the potential use of human induced pluripotent stem cells for the development of and research on medicinal products].
Takao Hayakawa, Hiroyuki Mizuguchi
Brain Nerve 2012 Jan; 64(1):47-57
PMID: Object id #258822223501 [PubMed - as supplied by publisher]