Treatments/Pipeline

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Pathological low frequency synchronization of the rat basal ganglia following the TTX-mediated blockade of the medial forebrain bundle: focus on the cortico-STN-GP pathway.
Salvatore Galati, Paolo Stanzione, Vincenza D'Angelo, Ernesto Fedele, Francesco Marzetti, Teresa Procopio, Alessandro Stefani
J Physiol 2009 Jul;
PMID: 19622605 [PubMed - as supplied by publisher]

Dopamine agonists for early Parkinson disease.
Nathan Hitzeman, Flora Rafii
Am Fam Physician 2009 Jul; 80(1):28
PMID: 19621842 [PubMed - as supplied by publisher]

Effect of deep brain stimulation of the subthalamic nucleus upon the contralateral subthalamic nucleus in Parkinson disease.
Peter Novak, Joshua A Klemp, Larry W Ridings, Kelly E Lyons, Rajesh Pahwa, Jules M Nazzaro
Neurosci Lett 2009 Jul;
PMID: 19616068 [PubMed - as supplied by publisher]

Reducing Dosing Frequency of Carbidopa/Levodopa: Double-blind Crossover Study Comparing Twice-Daily Bilayer Formulation of Carbidopa/Levodopa (IPX054) Versus 4 Daily Doses of Standard Carbidopa/Levodopa in Stable Parkinson Disease Patients.
Vanessa Hinson, Christopher Goetz, Sue Leurgans, Wenqing Fan, Tiffany Nguyen, Ann Hsu
Clin Neuropharmacol 2009 Jun;
PMID: 19620848 [PubMed - as supplied by publisher]

Using Modafinil to Treat Fatigue in Parkinson Disease: A Double-blind, Placebo-Controlled Pilot Study.
Jau-Shin Lou, Diana Dimitrova, Byung Park, Sarah Johnson, Ryan Eaton, Grace Arnold, John Nutt
Clin Neuropharmacol 2009 Jun;
PMID: 19620846 [PubMed - as supplied by publisher]

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model.
Beate Winner, Paula Desplats, Christian Hagl, Jochen Klucken, Robert Aigner, Sonja Ploetz, Jörn Laemke, Alexandra Karl, Ludwig Aigner, Eliezer Masliah, Erich Buerger, Jürgen Winkler
Exp Neurol 2009 Jul;
PMID: 19619535 [PubMed - as supplied by publisher]

Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction.
K A Stockwell, D Scheller, S Rose, M J Jackson, K Tayarani-Binazir, M M Iravani, L A Smith, C W Olanow, P Jenner
Exp Neurol 2009 Jul;
PMID: 19619533 [PubMed - as supplied by publisher]

Rivastigmine in Parkinson's disease dementia.
Shilpa Chitnis, Jayaraman Rao
Expert Opin Drug Metab Toxicol 2009 Aug; 5(8):941-55
PMID: 19619073 [PubMed - as supplied by publisher]

Electro-acupuncture stimulation improves motor disorders in Parkinsonian rats.
Jun Jia, Zuoli Sun, Bo Li, Yanli Pan, Haomin Wang, Xuan Wang, Fen Yu, Limin Liu, Lijuan Zhang, Xiaomin Wang
Behav Brain Res 2009 Jun;
PMID: 19549545 [PubMed - as supplied by publisher]

Genetic and environmental factors for hyperhomocysteinaemia and its clinical implications in Parkinson's disease.
Monika Bia?ecka, Piotr Robowski, Krystyna Honczarenko, Anna Roszmann, Jaros?aw S?awek
Neurol Neurochir Pol 2009 May-June; 43(3):272-285
PMID: 19618311 [PubMed - as supplied by publisher]

Istradefylline as monotherapy for Parkinson disease: Results of the 6002-US-051 trial.
H H Fernandez, D R Greeley, R M Zweig, J Wojcieszek, A Mori, N M Sussman,
Parkinsonism Relat Disord 2009 Jul;
PMID: 19616987 [PubMed - as supplied by publisher]

Gait disorders in Parkinson's disease: Clinical and pathophysiological approaches.
C Moreau, S Cantiniaux, A Delval, L Defebvre, J-P Azulay
Rev Neurol (Paris) 2009 Jul;
PMID: 19616816 [PubMed - as supplied by publisher]

Alleviation of drenching sweats following subthalamic deep brain stimulation in a patient with Parkinson's disease - A case report.
M K Sanghera, C Ward, R M Stewart, K Mewes, R K Simpson, E C Lai
J Neurol Sci 2009 Jul;
PMID: 19616221 [PubMed - as supplied by publisher]

Identification of metabolite profiles of the catechol-O-methyl transferase inhibitor tolcapone in rat urine using LC/MS-based metabonomics analysis.
Jinchun Sun, Linda S Von Tungeln, Wade Hines, Richard D Beger
J Chromatogr B Analyt Technol Biomed Life Sci 2009 Jun;
PMID: 19615953 [PubMed - as supplied by publisher]

Heparin binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons.
Marjo Piltonen, Maxim M Bespalov, Dagmar Ervasti, Tero Matilainen, Yulia A Sidorova, Heikki Rauvala, Mart Saarma, Pekka T Männistö
Exp Neurol 2009 Jul;
PMID: 19615368 [PubMed - as supplied by publisher]

Grafted neural stem cells migrate to substantia nigra and improve behavior in Parkinsonian rats.
Qing Feng Zhu, Ji Ma, Ling Li Yu, Chong Gang Yuan
Neurosci Lett 2009 Jul;
PMID: 19596403 [PubMed - as supplied by publisher]

Deep brain stimulation in neurological diseases and experimental models: From molecule to complex behavior.
Paolo Gubellini, Pascal Salin, Lydia Kerkerian-Le Goff, Christelle Baunez
Prog Neurobiol 2009 Jun;
PMID: 19559747 [PubMed - as supplied by publisher]

In vivo multimodal imaging of stem cell transplantation in a rodent model of Parkinson's disease.
Johanna Jackson, Catherine Chapon, William Jones, Ella Hirani, Abdullah Qassim, Kishore Bhakoo
J Neurosci Methods 2009 Jun;
PMID: 19559725 [PubMed - as supplied by publisher]

Isolation of Neural Crest Derived Chromaffin Progenitors from Adult Adrenal Medulla.
Kuei-Fang Chung, Flavie Sicard, Vladimir Vukicevic, Andreas Hermann, Alexander Storch, Wieland B Huttner, Stefan R Bornstein, Monika Ehrhart-Bornstein
Stem Cells 2009 Jul;
PMID: 19609938 [PubMed - as supplied by publisher]

Pharmacokinetics and Safety in Rhesus Monkeys of a Monoclonal Antibody-GDNF Fusion Protein for Targeted Blood-Brain Barrier Delivery.
William Pardridge, Ruben Boado
Pharm Res 2009 Jul;
PMID: 19609743 [PubMed - as supplied by publisher]

(A)DME of the Dopamine Agonist Rotigotine in Man -- Administration by Intravenous Infusion or Transdermal Delivery.
Willi Cawello, Marina Braun, Hilmar Boekens
Drug Metab Dispos 2009 Jul;
PMID: 19608695 [PubMed - as supplied by publisher]

A Bayesian statistical analysis of behavioral facilitation associated with deep brain stimulation.
Anne C Smith, Sudhin A Shah, Andrew E Hudson, Keith P Purpura, Jonathan D Victor, Emery N Brown, Nicholas D Schiff
J Neurosci Methods 2009 Jul;
PMID: 19576932 [PubMed - as supplied by publisher]

Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications.
Hong Qing, Winnie Wong, Edith G McGeer, Patrick L McGeer
Biochem Biophys Res Commun 2009 Jul;
PMID: 19576176 [PubMed - as supplied by publisher]

Differential Involvement of D1 and D2 Dopamine Receptors in L-DOPA-Induced Angiogenic Activity in a Rat Model of Parkinson's Disease.
Hanna S Lindgren, K Elisabet Ohlin, M Angela Cenci
Neuropsychopharmacology 2009 Jul;
PMID: 19606087 [PubMed - as supplied by publisher]

Therapeutic extradural cortical stimulation for Parkinson's Disease: Report of six cases and review of the literature.
Julio C Gutiérrez, Fernando J Seijo, Marco A Álvarez Vega, Fernando Fernández González, Beatriz Lozano Aragoneses, Marta Blázquez
Clin Neurol Neurosurg 2009 Jul;
PMID: 19604625 [PubMed - as supplied by publisher]

Adult neurotrophic factor-secreting stem cells: a potential novel therapy for neurodegenerative diseases.
Ofer Sadan, Noam Shemesh, Yoram Cohen, Eldad Melamed, Daniel Offen
Isr Med Assoc J 2009 Apr; 11(4):201-4
PMID: 19603590 [PubMed - as supplied by publisher]

Review of the economic evidence on the use of deep brain stimulation in late stage Parkinson's disease.
J Puig-Junoy, R Puig Peiró
Neurologia 2009 May; 24(4):220-9
PMID: 19603291 [PubMed - as supplied by publisher]

Conditions for Tumor-free and Dopamine Neuron-enriched Grafts After Transplanting Human ES Cell-derived Neural Precursor Cells.
Ji-Yun Ko, Hyun-Seob Lee, Chang-Hwan Park, Hyun-Chul Koh, Yong-Sung Lee, Sang-Hun Lee
Mol Ther 2009 Jul;
PMID: 19603007 [PubMed - as supplied by publisher]

Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: Common implication of striatal neuropeptides.
Mohamed Khalil Tamim, Pershia Samadi, Marc Morissette, Laurent Grégoire, Bazoumana Ouattara, Daniel Lévesque, Claude Rouillard, Thérèse Di Paolo
Neuropharmacology 2009 Jul;
PMID: 19576910 [PubMed - as supplied by publisher]

Cerebellar magnetic stimulation decreases levodopa-induced dyskinesias in Parkinson disease.
G Koch, L Brusa, F Carrillo, E Lo Gerfo, S Torriero, M Oliveri, P Mir, C Caltagirone, P Stanzione
Neurology 2009 Jul; 73(2):113-9
PMID: 19597133 [PubMed - as supplied by publisher]

Determinants of the Timing of Symptomatic Treatment in Early Parkinson Disease: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) Experience.
Sotirios A Parashos, Christopher J Swearingen, Kevin M Biglan, Ivan Bodis-Wollner, Grace S Liang, G Webster Ross, Barbara C Tilley, Lisa M Shulman,
Arch Neurol 2009 Jul;
PMID: 19597081 [PubMed - as supplied by publisher]

Deep brain stimulation for Parkinson's disease: Australian referral guidelines.
Paul Silberstein, Richard G Bittar, Richard Boyle, Raymond Cook, Terry Coyne, Dudley O'Sullivan, Malcolm Pell, Richard Peppard, Julian Rodrigues, Peter Silburn, Rick Stell, Peter Watson,
J Clin Neurosci 2009 Aug; 16(8):1001-8
PMID: 19596113 [PubMed - as supplied by publisher]

Zonisamide: in Parkinson's disease.
Lily P H Yang, Caroline M Perry
CNS Drugs 2009 ; 23(8):703-11
PMID: 19594199 [PubMed - as supplied by publisher]

Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease.
Ming Ming, Xuping Li, Xiaolan Fan, Dehua Yang, Liang Li, Sheng Chen, Qing Gu, Weidong Le
J Transl Med 2009 ; 7:53
PMID: 19558709 [PubMed - as supplied by publisher]

Anaesthesia for deep brain stimulation and in patients with implanted neurostimulator devices.
C C M Poon, M G Irwin
Br J Anaesth 2009 Aug; 103(2):152-65
PMID: 19556271 [PubMed - as supplied by publisher]

Chemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary culture.
Fanny Schmidt, Pierre Champy, Blandine Séon-Méniel, Xavier Franck, Rita Raisman-Vozari, Bruno Figadère
PLoS One 2009 ; 4(7):e6215
PMID: 19593444 [PubMed - as supplied by publisher]

Proprioception and Motor Control in Parkinson's Disease.
Jürgen Konczak, Daniel Corcos, Fay Horak, Howard Poizner, Mark Shapiro, Paul Tuite, Jens Volkmann, Matthias Maschke
J Mot Behav 2009 Jul; :1-11
PMID: 19592360 [PubMed - as supplied by publisher]

Recent advances in cell and gene therapies for Parkinson's disease
Toru Yasuda, Hideki Mochizuki
Nippon Rinsho 2009 Jul; 67(7):1429-38
PMID: 19591298 [PubMed - as supplied by publisher]

Reduced performance in balance, walking and turning tasks is associated with increased neck tone in Parkinson's disease.
Erika Franzén, Caroline Paquette, Victor S Gurfinkel, Paul J Cordo, John G Nutt, Fay B Horak
Exp Neurol 2009 Jun;
PMID: 19573528 [PubMed - as supplied by publisher]

Antidepressant effects of pramipexole, a dopamine D(3)/D(2) receptor agonist, and 7-OH-DPAT, a dopamine D(3) receptor agonist, in olfactory bulbectomized rats.
Megan E Breuer, Lucianne Groenink, Ronald S Oosting, Erich Buerger, Michiel Korte, Boris Ferger, Berend Olivier
Eur J Pharmacol 2009 Jun;
PMID: 19549514 [PubMed - as supplied by publisher]

The role of the subthalamic nucleus in response inhibition: Evidence from deep brain stimulation for Parkinson's disease.
N J Ray, N Jenkinson, J Brittain, P Holland, C Joint, D Nandi, P G Bain, N Yousif, A Green, J S Stein, T Z Aziz
Neuropsychologia 2009 Jun;
PMID: 19540864 [PubMed - as supplied by publisher]

Efficacy of rivastigmine for cognitive symptoms in Parkinson disease with dementia.
Amy C Almaraz, Erika D Driver-Dunckley, Bryan K Woodruff, Kay E Wellik, Richard J Caselli, Bart M Demaerschalk, Charles H Adler, John N Caviness, Dean M Wingerchuk
Neurologist 2009 Jul; 15(4):234-7
PMID: 19590387 [PubMed - as supplied by publisher]

Evaluation of the Effects of Deep Brain Stimulation of the Subthalamic Nucleus and Levodopa Treatment on Parkinsonian Voice Using Perturbation, Nonlinear Dynamic, and Perceptual Analysis.
Xiao Ping Zhou, Victoria S Lee, Emily Q Wang, Jack J Jiang
Folia Phoniatr Logop 2009 Jul; 61(4):189-199
PMID: 19590218 [PubMed - as supplied by publisher]

Levodopa/carbidopa/entacapone in Parkinson's disease.
Lauren C Seeberger, Robert A Hauser
Expert Rev Neurother 2009 Jul; 9(7):929-40
PMID: 19589043 [PubMed - as supplied by publisher]

Impact of subthalamic stimulation and medication on proximal and distal bradykinesia in Parkinson's disease.
M Potter-Nerger, R Wenzelburger, G Deuschl, J Volkmann
Eur Neurol 2009 ; 62(2):114-9
PMID: 19521088 [PubMed - as supplied by publisher]

Effect of high frequency repetitive transcranial magnetic stimulation on reaction time, clinical features and cognitive functions in patients with Parkinson's disease.
Silvie Sedlá?ková, Irena Rektorová, Hana Srovnalová, Ivan Rektor
J Neural Transm 2009 Jul;
PMID: 19588221 [PubMed - as supplied by publisher]

Scoliosis in patients with Parkinson's disease.
Jong Sam Baik, Jeong Yeon Kim, Joong Hyun Park, Sang Won Han, Jae Hyeon Park, Myung Sik Lee
J Clin Neurol 2009 Jun; 5(2):91-4
PMID: 19587816 [PubMed - as supplied by publisher]

Tremor.
Jan Raethjen, Günther Deuschl
Curr Opin Neurol 2009 Aug; 22(4):400-5
PMID: 19553813 [PubMed - as supplied by publisher]

Long term experience with Stalevo in Szeged, Hungary
Péter Klivényi, László Vécsei
Ideggyogy Sz 2009 May; 62(5-6):178-80
PMID: 19579666 [PubMed - as supplied by publisher]

Dopamine D(1) Receptor Gene Expression Studies in Unilateral 6-Hydroxydopamine-Lesioned Parkinson's Rat: Effect of 5-HT, GABA, and Bone Marrow Cell Supplementation.
M Nandhu, E Fabia, C Paulose
J Mol Neurosci 2009 Jul;
PMID: 19578995 [PubMed - as supplied by publisher]

Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis.
Sarah L Kinnings, Nina Liu, Nancy Buchmeier, Peter J Tonge, Lei Xie, Philip E Bourne
PLoS Comput Biol 2009 Jul; 5(7):e1000423
PMID: 19578428 [PubMed - as supplied by publisher]

Impulse control disorders in Parkinson's disease in a Chinese population.
Wenhui Fan, Hui Ding, Jinghong Ma, Piu Chan
Neurosci Lett 2009 Jun;
PMID: 19560522 [PubMed - as supplied by publisher]

Spectral Analysis of Field Potential Recordings by Deep Brain Stimulation Electrode for Localization of Subthalamic Nucleus in Patients with Parkinson's Disease.
Yasushi Miyagi, Tsuyoshi Okamoto, Takato Morioka, Shozo Tobimatsu, Yoshitaka Nakanishi, Kazuyuki Aihara, Kimiaki Hashiguchi, Nobuya Murakami, Fumiaki Yoshida, Kazuhiro Samura, Shinji Nagata, Tomio Sasaki
Stereotact Funct Neurosurg 2009 Jun; 87(4):211-218
PMID: 19571612 [PubMed - as supplied by publisher]

Early versus delayed initiation of entacapone in levodopa-treated patients with Parkinson's disease: a long-term, retrospective analysis.
H Nissinen, M Kuoppamäki, M Leinonen, A H Schapira
Eur J Neurol 2009 Jun;
PMID: 19570145 [PubMed - as supplied by publisher]

Role of deep brain stimulation in modulating memory formation and recall.
Rollin Hu, Emad Eskandar, Ziv Williams
Neurosurg Focus 2009 Jul; 27(1):E3
PMID: 19569891 [PubMed - as supplied by publisher]

At-risk for pathological gambling: imaging neural reward processing under chronic dopamine agonists.
Birgit Abler, Roman Hahlbrock, Alexander Unrath, Georg Grön, Jan Kassubek
Brain 2009 Jun;
PMID: 19567700 [PubMed - as supplied by publisher]

Systematic evaluation on influence of doparminergic therapy: on motor complications in Parkinson's disease
Ming-Zhu Zhou, Zhen-Guo Liu, Wei Chen, Li-Xia Lu, Jia-Ying Wu, Chen Qi
Zhonghua Yi Xue Za Zhi 2009 Feb; 89(7):438-44
PMID: 19567089 [PubMed - as supplied by publisher]

Botulinum toxin B increases mouth opening in patients with spastic trismus.
U M Fietzek, P Kossmehl, A Barthels, G Ebersbach, B Zynda, J Wissel
Eur J Neurol 2009 Jun;
PMID: 19566902 [PubMed - as supplied by publisher]

Delayed and lasting effects of deep brain stimulation on locomotion in Parkinson's disease.
Anne Beuter, Julien Modolo
Chaos 2009 Jun; 19(2):026114
PMID: 19566274 [PubMed - as supplied by publisher]

Dopamine Agonists and their risk to induce psychotic episodes in Parkinson's disease: a case-control study.
Daniel Ecker, Alexander Unrath, Jan Kassubek, Michael Sabolek
BMC Neurol 2009 ; 9:23
PMID: 19515253 [PubMed - as supplied by publisher]

A possible relation of BDNF and GDNF to neuropsychiatric disorders
Yoko Hibi, Atsumi Nitta, Toshitaka Nabeshima, Kiyofumi Yamada
Nihon Shinkei Seishin Yakurigaku Zasshi 2009 Apr; 29(2):85-9
PMID: 19562947 [PubMed - as supplied by publisher]

Frequency-specific effects of stimulation of the subthalamic area in treated Parkinson's disease patients.
Andrea A Kühn, Noa Fogelson, Patricia Dowsey Limousin, Marwan I Hariz, Andreas Kupsch, Peter Brown
Neuroreport 2009 Jul; 20(11):975-8
PMID: 19525877 [PubMed - as supplied by publisher]

Association of DRD3 and GRIN2B with impulse control and related behaviors in Parkinson's disease.
Jee-Young Lee, Eun Kyung Lee, Sung Sup Park, Ji-Yeon Lim, Hee Jin Kim, Ji Sun Kim, Beom S Jeon
Mov Disord 2009 Jun;
PMID: 19562769 [PubMed - as supplied by publisher]

In vivo pharmacology of endocannabinoids and their metabolic inhibitors: Therapeutic implications in Parkinson's disease and abuse liability.
Andrea Giuffrida, Lance R McMahon
Prostaglandins Other Lipid Mediat 2009 Jun;
PMID: 19523530 [PubMed - as supplied by publisher]

Reconsiderations in the treatment of Parkinson's disease with levodopa: some pharmacodynamic evidence
M Zappia, A Nicoletti, D Muñoz-S, J Tapia-Núñez
Rev Neurol 2009 Jul 1-15; 49(1):33-40
PMID: 19557698 [PubMed - as supplied by publisher]

A randomized controlled trial of quetiapine for psychosis in Parkinson's disease.
Paul Shotbolt, Michael Samuel, Chris Fox, Anthony S David
Neuropsychiatr Dis Treat 2009 ; 5:327-32
PMID: 19557142 [PubMed - as supplied by publisher]

Electrode displacement after intracerebral hematoma as a complication of a deep brain stimulation procedure.
Domenico Servello, Marco Sassi, Stefano Bastianello, Guy Umberto Poloni, Francesca Mancini, Claudio Pacchetti
Neuropsychiatr Dis Treat 2009 ; 5:183-7
PMID: 19557113 [PubMed - as supplied by publisher]

Restless legs syndrome: differential diagnosis and management with rotigotine.
Giovanni Merlino, Anna Serafini, Francesca Robiony, Mariarosaria Valente, Gian Luigi Gigli
Neuropsychiatr Dis Treat 2009 ; 5:67-80
PMID: 19557102 [PubMed - as supplied by publisher]

Update on ropinirole in the treatment of Parkinson's disease.
Holly A Shill, Mark Stacy
Neuropsychiatr Dis Treat 2009 ; 5:33-6
PMID: 19557097 [PubMed - as supplied by publisher]

Prognostic Factors of Subthalamic Stimulation in Parkinson's Disease: A Comparative Study between Short- and Long-Term Effects.
Sheng-Tzung Tsai, Sheng-Huang Lin, Yu-Cheng Chou, Yan-Hong Pan, Hsiang-Yi Hung, Chi-Wei Li, Shinn-Zong Lin, Shin-Yuan Chen
Stereotact Funct Neurosurg 2009 Jun; 87(4):241-248
PMID: 19556833 [PubMed - as supplied by publisher]

Future directions: use of interventional MRI for cell-based therapy of Parkinson disease.
Joshua Roskom, Andrzej Swistowski, Xianmin Zeng, Daniel A Lim
Neurosurg Clin N Am 2009 Apr; 20(2):211-8
PMID: 19555884 [PubMed - as supplied by publisher]

Surgical treatment of movement disorders.
Benzi M Kluger, Olga Klepitskaya, Michael S Okun
Neurol Clin 2009 Aug; 27(3):633-77, v
PMID: 19555825 [PubMed - as supplied by publisher]

Neuroprotection in a 6-hydroxydopamine-lesioned Parkinson model using lactoferrin-modified nanoparticles.
Rongqin Huang, Liang Han, Jianhua Li, Feiliang Ren, Weilun Ke, Chen Jiang, Yuanying Pei
J Gene Med 2009 Jun;
PMID: 19554623 [PubMed - as supplied by publisher]

Deep brain stimulation effects on gait variability in Parkinson's disease.
Jeffrey M Hausdorff, Leor Gruendlinger, Lisa Scollins, Siobhan O'Herron, Daniel Tarsy
Mov Disord 2009 Jun;
PMID: 19554569 [PubMed - as supplied by publisher]

Health related quality of life in early Parkinson's disease: Impact of motor and non-motor symptoms, results from Chinese levodopa exposed cohort.
Zhaohui Qin, Liyan Zhang, Fei Sun, Xianghua Fang, Cheryl Meng, Caroline Tanner, Piu Chan,
Parkinsonism Relat Disord 2009 Jun;
PMID: 19553154 [PubMed - as supplied by publisher]

Dopamine dysregulation syndrome, impulse control disorders and punding after deep brain stimulation surgery for Parkinson's disease.
Shen-Yang Lim, Sean S O'Sullivan, Katya Kotschet, David A Gallagher, Cameron Lacey, Andrew D Lawrence, Andrew J Lees, Dudley J O'Sullivan, Richard F Peppard, Julian P Rodrigues, Anette Schrag, Paul Silberstein, Stephen Tisch, Andrew H Evans
J Clin Neurosci 2009 Jun;
PMID: 19553125 [PubMed - as supplied by publisher]

Role of Serotoninergic Pathways in Drug-Induced Valvular Heart Disease and Diagnostic Features by Echocardiography.
Sakima A Smith, Alan D Waggoner, Lisa de Las Fuentes, Victor G Davila-Roman
J Am Soc Echocardiogr 2009 Jun;
PMID: 19553085 [PubMed - as supplied by publisher]

Blocking Receptor Protein Tyrosine Phosphatasebeta/zeta: A Potential Therapeutic Strategy for Parkinson's Disease.
Gonzalo Herradón, Laura Ezquerra
Curr Med Chem 2009 Sep;
PMID: 19548869 [PubMed - as supplied by publisher]

Revelations and revolutions in the understanding of Parkinson's disease.
Ted M Dawson, Darren J Moore, Andrew B West
Biochim Biophys Acta 2009 Jul; 1792(7):585-6
PMID: 19539178 [PubMed - as supplied by publisher]

Levodopa in the treatment of Parkinson's disease.
A H V Schapira, M Emre, P Jenner, W Poewe
Eur J Neurol 2009 Jun;
PMID: 19538218 [PubMed - as supplied by publisher]

Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial.
Dag Aarsland, Clive Ballard, Zuzana Walker, Fredrik Bostrom, Guido Alves, Katja Kossakowski, Iracema Leroi, Francisco Pozo-Rodriguez, Lennart Minthon, Elisabet Londos
Lancet Neurol 2009 Jul; 8(7):613-8
PMID: 19520613 [PubMed - as supplied by publisher]

Dopamine agonist: pathological gambling and hypersexuality.
Prescrire Int 2008 Oct; 17(97):200-1
PMID: 19536937 [PubMed - as supplied by publisher]

Reduced levodopa-induced complications after 5 years of subthalamic stimulation in Parkinson's disease: a second honeymoon.
Clemence Simonin, M Tir, D Devos, A Kreisler, K Dujardin, J Salleron, A Delval, S Blond, L Defebvre, A Destée, P Krystkowiak
J Neurol 2009 Jun;
PMID: 19536584 [PubMed - as supplied by publisher]

Novel Neuroprotective Mechanisms of Memantine: Increase in Neurotrophic Factor Release from Astroglia and Anti-Inflammation by Preventing Microglial Activation.
Hung-Ming Wu, Nian-Sheng Tzeng, Li Qian, Sung-Jen Wei, Xiaoming Hu, Shih-Heng Chen, Scott M Rawls, Patrick Flood, Jau-Shyong Hong, Ru-Band Lu
Neuropsychopharmacology 2009 Jun;
PMID: 19536110 [PubMed - as supplied by publisher]

Dopamine-deprived striatal GABAergic interneurons burst and generate repetitive gigantic IPSCs in medium spiny neurons.
Nathalie Dehorter, Celine Guigoni, Catherine Lopez, June Hirsch, Alexandre Eusebio, Yehezkel Ben-Ari, Constance Hammond
J Neurosci 2009 Jun; 29(24):7776-87
PMID: 19535589 [PubMed - as supplied by publisher]

Activation of phosphatidylinositol-linked D1-like receptor modulates FGF-2 expression in astrocytes via IP3-dependent Ca2+ signaling.
Xinhua Zhang, Zheng Zhou, Dakui Wang, Aiqun Li, Yanqing Yin, Xiaosong Gu, Fei Ding, Xuechu Zhen, Jiawei Zhou
J Neurosci 2009 Jun; 29(24):7766-75
PMID: 19535588 [PubMed - as supplied by publisher]

The Pro-apoptotic Substance Thapsigargin Selectively Stimulates Re-growth of Brain Capillaries.
Celine Ullrich, Christian Humpel
Curr Neurovasc Res 2009 Aug;
PMID: 19534719 [PubMed - as supplied by publisher]

Delimiting subterritories of the human subthalamic nucleus by means of microelectrode recordings and a Hidden Markov Model.
Adam Zaidel, Alexander Spivak, Lavi Shpigelman, Hagai Bergman, Zvi Israel
Mov Disord 2009 Jun;
PMID: 19533755 [PubMed - as supplied by publisher]

Deep brain stimulation of the subthalamic nucleus improves intrinsic alertness in Parkinson's disease.
Bruno Fimm, Ines A Heber, Volker A Coenen, Christoph Fromm, Johannes Noth, Martin Kronenbuerger
Mov Disord 2009 Jun;
PMID: 19533754 [PubMed - as supplied by publisher]

Parsing brain activity associated with acupuncture treatment in Parkinson's diseases.
Younbyoung Chae, Hyejung Lee, Hackjin Kim, Chang-Hwan Kim, Dae-Il Chang, Kyung-Mi Kim, Hi-Joon Park
Mov Disord 2009 Jun;
PMID: 19533753 [PubMed - as supplied by publisher]

Agonist or levodopa for Parkinson disease? Ultimately, it doesn't matter; neither is good enough.
Erwin B Montgomery
Neurology 2009 Jun; 72(24):2137; author reply 2137-8
PMID: 19528526 [PubMed - as supplied by publisher]

Metabolic Control Analysis in a Cellular Model of Elevated MAO-B: Relevance to Parkinson's Disease.
Jyothi Mallajosyula, Shankar Chinta, Subramanian Rajagopalan, David Nicholls, Julie Andersen
Neurotox Res 2009 Mar;
PMID: 19526285 [PubMed - as supplied by publisher]

Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism.
Corinne Beurrier, Sebastien Lopez, Delphine Révy, Chelliah Selvam, Cyril Goudet, Morgane Lhérondel, Paolo Gubellini, Lydia Kerkerian-Legoff, Francine Acher, Jean-Philippe Pin, Marianne Amalric
FASEB J 2009 Jun;
PMID: 19525404 [PubMed - as supplied by publisher]

Parkinson's disease.
Andrew J Lees, John Hardy, Tamas Revesz
Lancet 2009 Jun; 373(9680):2055-66
PMID: 19524782 [PubMed - as supplied by publisher]

Review of Lithium Effects on Brain and Blood.
Wise Young
Cell Transplant 2009 May;
PMID: 19523343 [PubMed - as supplied by publisher]

Generation of Dopamine Neurons With Improved Cell Survival And Phenotype Maintenance Using A Degradation-Resistant Nurr1 Mutant.
A-Young Jo, Mi-Young Kim, Hyun-Seob Lee, Yong-Hee Rhee, Jeong-Eun Lee, Kwang-Hyun Baek, Chang-Hwan Park, Hyun-Chul Koh, Incheol Shin, Yong-Sung Lee, Sang-Hun Lee
Stem Cells 2009 Jun;
PMID: 19522012 [PubMed - as supplied by publisher]

Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: implications for Parkinson's disease treatment.
Dario Cuomo, Giuseppina Martella, Emanuela Barabino, Paola Platania, Daniela Vita, Graziella Madeo, Chelliah Selvam, Cyril Goudet, Nadia Oueslati, Jean-Philippe Pin, Francine Acher, Antonio Pisani, Corinne Beurrier, Christophe Melon, Lydia Kerkerian-Le Goff, Paolo Gubellini
J Neurochem 2009 May; 109(4):1096-105
PMID: 19519781 [PubMed - as supplied by publisher]

Cell-based therapies in Parkinson's disease.
Paul Greene
Curr Neurol Neurosci Rep 2009 Jul; 9(4):292-7
PMID: 19515281 [PubMed - as supplied by publisher]

Bilateral deep brain stimulation versus best medical therapy for patients with advanced Parkinson's disease.
Shyamal H Mehta, Kapil D Sethi
Curr Neurol Neurosci Rep 2009 Jul; 9(4):266-7
PMID: 19515276 [PubMed - as supplied by publisher]

Deep brain stimulation and cognitive functions in Parkinson's disease: A three-year controlled study.
Roberta Zangaglia, Claudio Pacchetti, Chiara Pasotti, Francesca Mancini, Domenico Servello, Elena Sinforiani, Silvano Cristina, Marco Sassi, Giuseppe Nappi
Mov Disord 2009 Jun;
PMID: 19514093 [PubMed - as supplied by publisher]