Treatments/Pipeline

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Blocking LINGO-1 as a Therapy to Promote CNS Repair: From Concept to the Clinic.
Sha Mi, R Blake Pepinsky, Diego Cadavid
CNS Drugs 2013 May;
PMID: Object id #158323681979 [PubMed - as supplied by publisher]

Pramipexole Reduces Phosphorylation of ?-Synuclein at Serine-129.
Kai-Yin Chau, J Mark Cooper, Anthony Henry V Schapira
J Mol Neurosci 2013 May;
PMID: Object id #251123681749 [PubMed - as supplied by publisher]

Progress in Stem Cell Therapy for Major Human Neurological Disorders.
P L Martínez-Morales, A Revilla, I Ocaña, C González, P Sainz, D McGuire, I Liste
Stem Cell Rev 2013 May;
PMID: Object id #256123681704 [PubMed - as supplied by publisher]

Initial cognitive dip after subthalamic deep brain stimulation in Parkinson disease.
Han-Joon Kim, Beom S Jeon, Ji Young Yun, Young Eun Kim, Hui-Jun Yang, Sun Ha Paek
J Neurol 2013 May;
PMID: Object id #259723681647 [PubMed - as supplied by publisher]

Urinary profile of catecholamines and metabolites in Parkinson patients with deep brain stimulation.
J Guimarães, M A Vieira-Coelho, E Moura, J Afonso, M J Rosas, R Vaz, C Garrett
Eur J Neurol 2013 May;
PMID: Object id #262623679894 [PubMed - as supplied by publisher]

Antioxidant and cytoprotective effects of an ethanol extract of Acalypha wilkesiana var. macafeana from Malaysia.
Wardah M Din, Jessica Chu, Garry Clarke, Khoo T Jin, Tracey D Bradshaw, Jeff R Fry, Christophe Wiart
Nat Prod Commun 2013 Mar; 8(3):375-80
PMID: Object id #153123678815 [PubMed - as supplied by publisher]

Scientific and ethical issues related to stem cell research and interventions in neurodegenerative disorders of the brain.
Roger A Barker, Inez de Beaufort
Prog Neurobiol 2013 May;
PMID: Object id #230623665410 [PubMed - as supplied by publisher]

Reaching to proprioceptively defined targets in Parkinson's disease: Effects of deep brain stimulation therapy.
D Lee, D Y Henriques, J Snider, D Song, H Poizner
Neuroscience 2013 Apr; 244C:99-112
PMID: Object id #9123590906 [PubMed - as supplied by publisher]

CRACK COCAINE USE DUE TO DOPAMINE AGONIST THERAPY IN PARKINSON DISEASE.
Joseph H Friedman, Victoria Chang
Neurology 2013 May;
PMID: Object id #156823677745 [PubMed - as supplied by publisher]

Degradation of stored movement representations in the parkinsonian brain and the impact of levodopa.
Jolyn N A D'Andrea, Angela M Haffenden, Sarah Furtado, Oksana Suchowersky, Bradley G Goodyear
Neuropsychologia 2013 Apr; 51(7):1195-1203
PMID: Object id #11923591046 [PubMed - as supplied by publisher]

Variability in neuronal expression of dopamine receptors and transporters in the substantia nigra.
Stefanie Reyes, Veronica Cottam, Deniz Kirik, Kay L Double, Glenda M Halliday
Mov Disord 2013 May;
PMID: Object id #159823674405 [PubMed - as supplied by publisher]

Pharmacokinetic considerations for the use of levodopa in the treatment of Parkinson disease: focus on levodopa/carbidopa/entacapone for treatment of levodopa-associated motor complications.
Thomas Müller
Clin Neuropharmacol 2013 May-Jun; 36(3):84-91
PMID: Object id #248523673910 [PubMed - as supplied by publisher]

Cellular Uptake Mechanism and Therapeutic Utility of a Novel Peptide in Targeted-Delivery of Proteins into Neuronal Cells.
Ailing Fu, Zizhen Zhao, Feiyan Gao, Miaomiao Zhang
Pharm Res 2013 May;
PMID: Object id #249423673555 [PubMed - as supplied by publisher]

An osteoporotic fracture mimicking cervical dystonia in idiopathic Parkinson's disease.
Caroline Ostrowski, Lindsay Ronan, Ray Sheridan, Vaughan Pearce
Age Ageing 2013 May;
PMID: Object id #246823672934 [PubMed - as supplied by publisher]

Pluripotent stem cells for Parkinson's disease: progress and challenges.
Xianmin Zeng, Larry A Couture
Stem Cell Res Ther 2013 Apr; 4(2):25
PMID: Object id #238723672848 [PubMed - as supplied by publisher]

Motor and cognitive placebo-/nocebo-responses in Parkinson's disease patients with deep brain stimulation.
Ariane Keitel, Lars Wojtecki, Jan Hirschmann, Christian J Hartmann, Stefano Ferrea, Martin Südmeyer, Alfons Schnitzler
Behav Brain Res 2013 May;
PMID: Object id #206023651878 [PubMed - as supplied by publisher]

Behavioral characterization of the 6-hydroxidopamine model of Parkinson's disease and pharmacological rescuing of non-motor deficits.
Miguel M Carvalho, Filipa L Campos, Bárbara Coimbra, José M Pêgo, Carla Rodrigues, Rui Lima, Ana J Rodrigues, Nuno Sousa, António J Salgado
Mol Neurodegener 2013 ; 8(1):14
PMID: Object id #93823621954 [PubMed - as supplied by publisher]

Stem Cells from Wildtype and Friedreich's Ataxia Mice Present Similar Neuroprotective Properties in Dorsal Root Ganglia Cells.
Jonathan Jones, Alicia Estirado, Carolina Redondo, Salvador Martinez
PLoS One 2013 ; 8(5):e62807
PMID: Object id #242123671637 [PubMed - as supplied by publisher]

Bioengineered stem cells in neural development and neurodegeneration research.
Shauna H Yuan, Mason Shaner
Ageing Res Rev 2013 May;
PMID: Object id #202123651546 [PubMed - as supplied by publisher]

Biodegradable microparticles for strictly regulating the release of neurotrophic factors.
C Gujral, Y Minagawa, K Fujimoto, H Kitano, T Nakaji-Hirabayashi
J Control Release 2013 Apr; 168(3):307-316
PMID: Object id #275623578846 [PubMed - as supplied by publisher]

Suicide ideation and behaviours after STN and GPi DBS surgery for Parkinson's disease: results from a randomised, controlled trial.
Daniel Weintraub, John E Duda, Kimberly Carlson, Ping Luo, Oren Sagher, Matthew Stern, Kenneth A Follett, Domenic Reda, Frances M Weaver,
J Neurol Neurosurg Psychiatry 2013 May;
PMID: Object id #239323667214 [PubMed - as supplied by publisher]

Improved Cell Therapy Protocol for Parkinson's Disease Based on Differentiation Efficiency and Safety of Hesc-, Hipsc and Non-Human Primate Ipsc-Derived DA Neurons.
Sundberg Maria, Bogetofte Helle, Lawson Tristan, Smith Gaynor, Astradsson Arnar, Moore Michele, Osborn Teresia, Cooper Oliver, Spealman Roger, Hallett Penelope, Isacson Ole
Stem Cells 2013 May;
PMID: Object id #236323666606 [PubMed - as supplied by publisher]

Magnetic Resonance Spectroscopy to Assess NeuroInflammation and Neuropathic Pain.
Linda Chang, Sody M Munsaka, Stephanie Kraft-Terry, Thomas Ernst
J Neuroimmune Pharmacol 2013 May;
PMID: Object id #232623666436 [PubMed - as supplied by publisher]

Deep Brain Stimulation of the Subthalamic Nucleus for Peripherally Induced Parkinsonism.
José Fidel Baizabal-Carvallo, Joseph Jankovic
Neuromodulation 2013 May;
PMID: Object id #228423663196 [PubMed - as supplied by publisher]

Study on the levels of DA and metabolite in striatum in rats with Parkinson's disease treated by BDNF gene modified bone mesenchymal stem cells].
Gang-Yong Zhao, Lei Cui, Juan Gao, Rui-Ting Dai, Ping Zhang
Zhongguo Ying Yong Sheng Li Xue Za Zhi 2013 Jan; 29(1):82-5
PMID: Object id #223423662416 [PubMed - as supplied by publisher]

In vivo administration of VEGF- and GDNF-releasing biodegradable polymeric microspheres in a severe lesion model of Parkinson's disease.
E Herrán, J A Ruiz-Ortega, A Aristieta, M Igartua, C Requejo, J V Lafuente, L Ugedo, J L Pedraz, R M Hernández
Eur J Pharm Biopharm 2013 Apr;
PMID: Object id #146123639739 [PubMed - as supplied by publisher]

Midbrain dopaminergic neurons: A review of the molecular circuitry that regulates their development.
Shane V Hegarty, Aideen M Sullivan, Gerard W O'Keeffe
Dev Biol 2013 Apr;
PMID: Object id #52323603197 [PubMed - as supplied by publisher]

The effects of silent cerebral ischemic lesions on the prognosis of idiopathic Parkinson's disease.
In-Uk Song, Young-Do Kim, Hyun-Ji Cho, Sung-Woo Chung
Parkinsonism Relat Disord 2013 May;
PMID: Object id #223523660543 [PubMed - as supplied by publisher]

Effects of entacapone on plasma homocysteine in Parkinson's disease patients on levodopa].
Peng Zhao, Jun-Feng Yang, Wei Liu, Yu Wang, Ya-Nan Sun, Qi Li, Wei Zhang, Ben-Shu Zhang
Zhonghua Yi Xue Za Zhi 2013 Feb; 93(7):512-5
PMID: Object id #220923660319 [PubMed - as supplied by publisher]

Effect of long-term treatment with pramipexole or levodopa on presynaptic markers assessed by longitudinal [(123)I]FP-CIT SPECT and histochemistry.
Candan Depboylu, Lukas Maurer, Andreas Matusch, Guido Hermanns, Andrea Windolph, Martin Béhé, Wolfgang H Oertel, Günter U Höglinger
Neuroimage 2013 Apr;
PMID: Object id #119223631981 [PubMed - as supplied by publisher]

Stimulation of subthalamic nuclei restores a near normal planning strategy in Parkinson's patients.
Giovanni Mirabella, Sara Iaconelli, Nicola Modugno, Giorgio Giannini, Francesco Lena, Gianpaolo Cantore
PLoS One 2013 ; 8(5):e62793
PMID: Object id #215923658775 [PubMed - as supplied by publisher]

Use of "MGE Enhancers" for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons.
Ying-Jiun J Chen, Daniel Vogt, Yanling Wang, Axel Visel, Shanni N Silberberg, Cory R Nicholas, Teruko Danjo, Joshua L Pollack, Len A Pennacchio, Stewart Anderson, Yoshiki Sasai, Scott C Baraban, Arnold R Kriegstein, Arturo Alvarez-Buylla, John L R Rubenstein
PLoS One 2013 ; 8(5):e61956
PMID: Object id #215523658702 [PubMed - as supplied by publisher]

Pathological tremor prediction using surface electromyogram and acceleration: potential use in 'ON-OFF' demand driven deep brain stimulator design.
Ishita Basu, Daniel Graupe, Daniela Tuninetti, Pitamber Shukla, Konstantin V Slavin, Leo Verhagen Metman, Daniel M Corcos
J Neural Eng 2013 May; 10(3):036019
PMID: Object id #211223658233 [PubMed - as supplied by publisher]

Proteomic Analysis of the Cerebrospinal Fluid of Parkinson's Disease Patients Pre- and Post-Deep Brain Stimulation.
Er-Song Wang, Hui-Bin Yao, Ying-Hui Chen, Gan Wang, Wen-Wei Gao, Yi-Rui Sun, Ji-Guang Guo, Jian-Wen Hu, Cheng-Chuan Jiang, Jin Hu
Cell Physiol Biochem 2013 May; 31(4-5):625-637
PMID: Object id #209123652646 [PubMed - as supplied by publisher]

In vivo visualization and monitoring of viable neural stem cells using noninvasive bioluminescence imaging in the 6-hydroxydopamine-induced mouse model of Parkinson disease.
Hyung-Jun Im, Do Won Hwang, Han Kyu Lee, Jaeho Jang, Song Lee, Hyewon Youn, Yeona Jin, Seung U Kim, E Edmund Kim, Yong Sik Kim, Dong Soo Lee
Mol Imaging 2013 Jun; 12(4):224-34
PMID: Object id #200623651500 [PubMed - as supplied by publisher]

Current surgical treatment of Parkinson`s disease.
Sohail A Ansari, Antoine Nachanakian, Nabil M Biary
Neurosciences (Riyadh) 2003 Jan; 8(1):3-7
PMID: Object id #198023648977 [PubMed - as supplied by publisher]

Reply: Levodopa increases functional connectivity in the cerebellum and brainstem in Parkinson's disease.
Abraham Z Snyder, Joel S Perlmutter, Carl D Hacker
Brain 2013 Feb;
PMID: Object id #195723650223 [PubMed - as supplied by publisher]

Compliance with Pharmacotherapy and Direct Healthcare Costs in Patients with Parkinson's Disease: A Retrospective Claims Database Analysis.
Florent F Richy, Guilhem Pietri, Kimberly A Moran, Emmanuelle Senior, Lydia E Makaroff
Appl Health Econ Health Policy 2013 May;
PMID: Object id #193423649891 [PubMed - as supplied by publisher]

Role of BDNF in Central Motor Structures and Motor Diseases.
Yan-Yan He, Xiao-Yang Zhang, Wing-Ho Yung, Jing-Ning Zhu, Jian-Jun Wang
Mol Neurobiol 2013 May;
PMID: Object id #189223649659 [PubMed - as supplied by publisher]

The remarkable conformational plasticity of alpha-synuclein: blessing or curse?
Angélique Deleersnijder, Melanie Gerard, Zeger Debyser, Veerle Baekelandt
Trends Mol Med 2013 May;
PMID: Object id #187823648364 [PubMed - as supplied by publisher]

Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120).
Christopher D Herzog, Lamar Brown, Brian R Kruegel, Alistair Wilson, Malú G Tansey, Fred H Gage, Eugene M Johnson, Raymond T Bartus
Neurobiol Dis 2013 Apr;
PMID: Object id #116323631873 [PubMed - as supplied by publisher]

A Rapid Non Invasive L-DOPA-(13)C Breath Test for Optimally Suppressing Extracerebral AADC Enzyme Activity - Toward Individualizing Carbidopa Therapy in Parkinson's Disease.
Anil Modak, Raymon Durso, Ephraim Josephs, David Rosen
J Parkinsons Dis 2012 Jan; 2(4):349-356
PMID: Object id #185623646099 [PubMed - as supplied by publisher]

Neuromagnetic Evidence of Abnormal Movement-Related Beta Desynchronization in Parkinson's Disease.
Elizabeth Heinrichs-Graham, Tony W Wilson, Pamela M Santamaria, Sheila K Heithoff, Diego Torres-Russotto, Jessica A L Hutter-Saunders, Katherine A Estes, Jane L Meza, R L Mosley, Howard E Gendelman
Cereb Cortex 2013 May;
PMID: Object id #183323645717 [PubMed - as supplied by publisher]

Initial Treatment of Parkinson's Disease: An Update.
Scott Kaplan, Daniel Tarsy
Curr Treat Options Neurol 2013 May;
PMID: Object id #180123645294 [PubMed - as supplied by publisher]

Longitudinal assessment of tau and amyloid beta in cerebrospinal fluid of Parkinson disease.
Jing Zhang, Hayley A Mattison, Changqin Liu, Carmen Ginghina, Peggy Auinger, Michael P McDermott, Tessandra Stewart, Un Jung Kang, , Kevin C Cain, Min Shi
Acta Neuropathol 2013 May;
PMID: Object id #178223644819 [PubMed - as supplied by publisher]

Hemispheric dissociation of reward processing in humans: Insights from deep brain stimulation.
Stefano Palminteri, Giulia Serra, Anne Buot, Liane Schmidt, Marie-Laure Welter, Mathias Pessiglione
Cortex 2013 Mar;
PMID: Object id #174923643244 [PubMed - as supplied by publisher]

Levodopa changes the severity of freezing in Parkinson's disease.
Urban M Fietzek, Jens Zwosta, Frauke E Schroeteler, Kerstin Ziegler, Andres O Ceballos-Baumann
Parkinsonism Relat Disord 2013 May;
PMID: Object id #171923642712 [PubMed - as supplied by publisher]

Stimulation of the pedunculopontine tegmental nucleus may affect renal function by melanocortinergic signaling.
Cheng Liu, Da-Wei Ye, Xue-Hai Guan, Rong-Chun Li, Hong-Bing Xiang, Wen-Zhen Zhu
Med Hypotheses 2013 Apr;
PMID: Object id #169223642396 [PubMed - as supplied by publisher]

Suitability of the adenosine antagonist istradefylline for the treatment of Parkinson's disease: pharmacokinetic and clinical considerations.
Thomas Müller
Expert Opin Drug Metab Toxicol 2013 May;
PMID: Object id #166323642267 [PubMed - as supplied by publisher]

Differences Between Parkinson's and Huntington's Diseases and Their Role for Prioritization of Stem Cell-Based Treatments.
Kristina Hug, Göran Hermerén
Curr Mol Med 2013 May;
PMID: Object id #164623642059 [PubMed - as supplied by publisher]

Early application of deep brain stimulation: Clinical and ethical aspects.
Christiane Woopen, K Amande M Pauls, Anne Koy, Elena Moro, Lars Timmermann
Prog Neurobiol 2013 Apr;
PMID: Object id #104323628580 [PubMed - as supplied by publisher]

Neurogenic detrusor overactivity: an update on management options.
Pamela Ellsworth, Eugene B Cone
R I Med J (2013) 2013 ; 96(4):38-40
PMID: Object id #162023641451 [PubMed - as supplied by publisher]

Labeling and Tracking of Human Mesenchymal Stem Cells Using Near-Infrared Technology.
Marie-Therese Armentero, Patrizia Bossolasco, Lidia Cova
Methods Mol Biol 2013 May;
PMID: Object id #150923640251 [PubMed - as supplied by publisher]

Motor and non-motor symptoms of 1453 patients with Parkinson's disease: Prevalence and risks.
Asako Yoritaka, Yasushi Shimo, Masashi Takanashi, Jiro Fukae, Taku Hatano, Toshiki Nakahara, Nobukazu Miyamato, Takao Urabe, Hideo Mori, Nobutaka Hattori
Parkinsonism Relat Disord 2013 Apr;
PMID: Object id #149423639756 [PubMed - as supplied by publisher]

Dopamine D2 receptor-mediated modulation of adenosine A2A receptor agonist binding within the A2AR/D2R oligomer framework.
Víctor Fernández-Dueñas, Maricel Gómez-Soler, Xavier Morató, Fabiana Núñez, Arijit Das, T Santhosh Kumar, Serge Jaumà, Kenneth A Jacobson, Francisco Ciruela
Neurochem Int 2013 Apr;
PMID: Object id #88923619397 [PubMed - as supplied by publisher]

Apathy in patients with Parkinson disease as a function of side of onset.
Erica Harris, Patrick McNamara, Raymon Durso
J Geriatr Psychiatry Neurol 2013 Jun; 26(2):95-104
PMID: Object id #271223584852 [PubMed - as supplied by publisher]

Conversion of Local Anesthesia-Guided Deep Brain Stimulation of the Subthalamic Nucleus to General Anesthesia.
Ersoy Kocabicak, Dursun Aygun, Onur Alptekin, Hatice Guz, Murat Kurt, Binnur Sarihasan, Yasin Temel
J Neurol Surg A Cent Eur Neurosurg 2013 May;
PMID: Object id #143223636909 [PubMed - as supplied by publisher]

Rapid onset of efficacy of rasagiline in early Parkinson's disease.
Sandro Zambito Marsala, Roberta Vitaliani, Daniele Volpe, Francesca Capozzoli, Luciana Baroni, Enrico Belgrado, Carlo Borsato, Manuela Gioulis, Corrado Marchini, Angelo Antonini
Neurol Sci 2013 May;
PMID: Object id #140523636872 [PubMed - as supplied by publisher]

Rasagiline meta-analysis: a spotlight on clinical safety and adverse events when treating Parkinson's disease.
Julián Solís-García Del Pozo, Sara Mínguez-Mínguez, Piet Wj de Groot, Joaquín Jordán
Expert Opin Drug Saf 2013 May;
PMID: Object id #137123634791 [PubMed - as supplied by publisher]

Impulse control disorders and compulsive behaviors associated with dopaminergic therapies in Parkinson disease.
Howard D Weiss, Laura Marsh
Neurol Clin Pract 2012 Dec; 2(4):267-274
PMID: Object id #135023634371 [PubMed - as supplied by publisher]

Diagnosis and treatment of impulse control disorders in patients with movement disorders.
Tiago A Mestre, Antonio P Strafella, Teri Thomsen, Valerie Voon, Janis Miyasaki
Ther Adv Neurol Disord 2013 May; 6(3):175-88
PMID: Object id #132823634190 [PubMed - as supplied by publisher]

Conditioned medium from human amniotic epithelial cells may induce the differentiation of human umbilical cord blood mesenchymal stem cells into dopaminergic neuron-like cells.
Shu Yang, Hai-Mei Sun, Ji-Hong Yan, Hong Xue, Bo Wu, Fang Dong, Wen-Shuai Li, Feng-Qing Ji, De-Shan Zhou
J Neurosci Res 2013 Apr;
PMID: Object id #130223633297 [PubMed - as supplied by publisher]

Deep Brain Stimulation of the Subthalamic Nucleus Regulates Postabsorptive Glucose Metabolism in Patients With Parkinson's Disease.
Marie Batisse-Lignier, Isabelle Rieu, Christelle Guillet, Estelle Pujos, Béatrice Morio, Jean-Jacques Lemaire, Franck Durif, Yves Boirie
J Clin Endocrinol Metab 2013 Apr;
PMID: Object id #127123633215 [PubMed - as supplied by publisher]

Valproic acid-induced parkinsonism: Levodopa responsiveness with dyskinesia.
Michael Silver, Stewart A Factor
Parkinsonism Relat Disord 2013 Apr;
PMID: Object id #124423632325 [PubMed - as supplied by publisher]

Subthalamic deep brain stimulation versus best medical therapy for l-dopa responsive pain in Parkinson's disease.
Oguzkan Sürücü, Heide Baumann-Vogel, Mechtild Uhl, Lukas L Imbach, Christian R Baumann
Pain 2013 Mar;
PMID: Object id #122023632230 [PubMed - as supplied by publisher]

Dual Targeting of the Adenosine A2A Receptors and Monoamine Oxidase B by 4H-3,1-Benzothiazin-4-ones.
Anne Stößel, Sonja Hinz, Petra Küppers, Jag Heer, Michael Gütschow, Christa E Müller
J Med Chem 2013 Apr;
PMID: Object id #113323631427 [PubMed - as supplied by publisher]

Effect of expectancy and personality on cortical excitability in Parkinson's disease.
Jau-Shin Lou, Diana M Dimitrova, Richard Hammerschlag, John Nutt, Elizabeth A Hunt, Ryan W Eaton, Sarah C Johnson, Melanie D Davis, Grace C Arnold, Sarah B Andrea, And Barry S Oken
Mov Disord 2013 Apr;
PMID: Object id #110823630185 [PubMed - as supplied by publisher]

Factors predictive of the development of levodopa-induced dyskinesia and wearing-off in Parkinson's disease.
C Warren Olanow, Karl Kieburtz, Olivier Rascol, Werner Poewe, Anthony H Schapira, Murat Emre, Helena Nissinen, Mika Leinonen, Fabrizio Stocchi,
Mov Disord 2013 Apr;
PMID: Object id #107423630119 [PubMed - as supplied by publisher]

The effect of estrogen in a man with Parkinson's disease and a review of its therapeutic potential.
Chris Adams, Rajeev Kumar
Int J Neurosci 2013 Apr;
PMID: Object id #101523627690 [PubMed - as supplied by publisher]

PACAP Protects Against Salsolinol-Induced Toxicity in Dopaminergic SH-SY5Y Cells: Implication for Parkinson's Disease.
Dwayne Brown, Andrea Tamas, Dora Reglödi, Yousef Tizabi
J Mol Neurosci 2013 Apr;
PMID: Object id #99523625270 [PubMed - as supplied by publisher]

Successful long-term bilateral subthalamic nucleus deep brain stimulation in VPS35 Parkinson's disease.
Vanessa Fleury, Christian Wider, Judit Horvath, André Zacharia, Julien Bally, Pierre Pollak, Claudio Pollo, François J G Vingerhoets, Pierre R Burkhard
Parkinsonism Relat Disord 2013 Apr;
PMID: Object id #96923623008 [PubMed - as supplied by publisher]

Formulation and characterization of nanostructured lipid carrier of ubiquinone (Coenzyme Q10).
Basavaraj K Nanjwade, Vikrant T Kadam, F V Manvi
J Biomed Nanotechnol 2013 Mar; 9(3):450-60
PMID: Object id #90823621001 [PubMed - as supplied by publisher]

Pharmaceutical quality of seven generic Levodopa/Benserazide products compared with original Madopar(R) / Prolopa(R).
Urs E Gasser, Anton Fischer, Jan P Timmermans, Isabelle Arnet
BMC Pharmacol Toxicol 2013 Apr; 14(1):24
PMID: Object id #85623617953 [PubMed - as supplied by publisher]

Long-term subthalamic nucleus stimulation improves sensorimotor integration and proprioception.
Aparna Wagle Shukla, Elena Moro, Carolyn Gunraj, Andres Lozano, Mojgan Hodaie, Anthony Lang, Robert Chen
J Neurol Neurosurg Psychiatry 2013 Apr;
PMID: Object id #83023616568 [PubMed - as supplied by publisher]

Sexually Dimorphic Effects of Catechol-O-Methyltransferase (COMT) Inhibition on Dopamine Metabolism in Multiple Brain Regions.
Linda M Laatikainen, Trevor Sharp, Paul J Harrison, Elizabeth M Tunbridge
PLoS One 2013 ; 8(4):e61839
PMID: Object id #80523613951 [PubMed - as supplied by publisher]

Genetic variation in the human brain dopamine system influences motor learning and its modulation by L-dopa.
Kristin M Pearson-Fuhrhop, Brian Minton, Daniel Acevedo, Babak Shahbaba, Steven C Cramer
PLoS One 2013 ; 8(4):e61197
PMID: Object id #71623613810 [PubMed - as supplied by publisher]

Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease.
Guilherme T Valença, Philip G Glass, Nadja N Negreiros, Meirelayne B Duarte, Lais M G B Ventura, Mila Mueller, Jamary Oliveira-Filho
Parkinsonism Relat Disord 2013 Apr;
PMID: Object id #70123611687 [PubMed - as supplied by publisher]

Exercise: a possible adjunct therapy to alleviate early Parkinson disease.
Megan Konerth, Jennifer Childers
JAAPA 2013 Apr; 26(4):30-3
PMID: Object id #67223610834 [PubMed - as supplied by publisher]

Levodopa Responsiveness in Adult-onset Lower Limb Dystonia is Associated with the Development of Parkinson's Disease.
Florence C F Chang, Keith A Josephs
Tremor Other Hyperkinet Mov (N Y) 2013 ; 3
PMID: Object id #65423610745 [PubMed - as supplied by publisher]

Third degree atrioventricular block associated with treatment with rivastigmine transdermal patch.
Fredrikke C Knudtzen, Thomas B Christophersen
J Geriatr Cardiol 2013 Mar; 10(1):113-5
PMID: Object id #60323610582 [PubMed - as supplied by publisher]

The adverse event profile of perampanel: meta-analysis of randomized controlled trials.
G Zaccara, F Giovannelli, M Cincotta, A Verrotti, E Grillo
Eur J Neurol 2013 Apr;
PMID: Object id #59923607817 [PubMed - as supplied by publisher]

Synthesis of novel analogs of cabergoline: improving cardiovascular safety by removing 5-HT2B receptor agonism.
Peter I Dosa, Tim Ward, Michael A Walters, Suck Won Kim
ACS Med Chem Lett 2013 Feb; 4(2):254-258
PMID: Object id #56623606928 [PubMed - as supplied by publisher]

A case of Parkinson's disease treated effectively with a pacing board for repetitive speech phenomena after deep brain stimulation.
Junichiro Suzuki, Yasuhiro Tanaka, Hirohisa Watanabe, Mizuki Ito, Yasukazu Kajita, Gen Sobue
Rinsho Shinkeigaku 2013 ; 53(4):304-7
PMID: Object id #54723603546 [PubMed - as supplied by publisher]

Sex, Food and Threat: Startling Changes After Subthalamic Stimulation in Parkinson's Disease.
Tereza Serranová, Tomá? Sieger, Petr Du?ek, Filip R??i?ka, Du?an Urgo?ík, Ev?en R??i?ka, Josep Valls-Solé, Robert Jech
Brain Stimul 2013 Apr;
PMID: Object id #49823602024 [PubMed - as supplied by publisher]

Direct and Retrograde Transduction of Nigral Neurons with AAV6, 8 and 9, and Intraneuronal Persistence of Viral Particles.
Karin Irmgard Loew, Patrick Aebischer, Bernard Laurent Schneider
Hum Gene Ther 2013 Apr;
PMID: Object id #46823600720 [PubMed - as supplied by publisher]

Formulation and characterization of intranasal mucoadhesive nanoparticulates and thermo-reversible gel of levodopa for brain delivery.
Sumit Sharma, Shikha Lohan, R S R Murthy
Drug Dev Ind Pharm 2013 Apr;
PMID: Object id #44323600649 [PubMed - as supplied by publisher]

The Parkinson's disease associated LRRK2 mutation R1441G inhibits neuronal differentiation of neural stem cells.
Lamia'a Bahnassawy, Sarah Nicklas, Thomas Palm, Ingeborg Menzl, Fabian Birzele, Frank Gillardon, Jens Christian Schwamborn
Stem Cells Dev 2013 Apr;
PMID: Object id #42523600457 [PubMed - as supplied by publisher]

Effect and safety of duodenal levodopa infusion in advanced Parkinson's disease: a retrospective multicenter outcome assessment in patient routine care.
A Antonini, P Odin, L Opiano, V Tomantschger, C Pacchetti, B Pickut, U E Gasser, D Calandrella, F Mancini, M Zibetti, B Minafra, I Bertaina, P De Deyn, C Cras, E Wolf, S Spielberger, W Poewe
J Neural Transm 2013 Apr;
PMID: Object id #39823595879 [PubMed - as supplied by publisher]

Modulation of Beta oscillations in the subthalamic nucleus with prosaccades and antisaccades in Parkinson's disease.
Akihiro Yugeta, William D Hutchison, Clement Hamani, Utpal Saha, Andres M Lozano, Mojgan Hodaie, Elena Moro, Robert Chen
J Neurosci 2013 Apr; 33(16):6895-904
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Intracerebral transplantation of differentiated human embryonic stem cells to hemiparkinsonian monkeys.
Marina E Emborg, Zhijian Zhang, Valerie Joers, Kevin Brunner, Viktorya Bondarenko, Sachiko Ohshima, Su-Chun Zhang
Cell Transplant 2013 ; 22(5):831-8
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Striatal molecular signature of subchronic subthalamic nucleus high frequency stimulation in parkinsonian rat.
Sylviane Lortet, Emilie Lacombe, Nicolas Boulanger, Pascal Rihet, Catherine Nguyen, Lydia Kerkerian-Le Goff, Pascal Salin
PLoS One 2013 ; 8(4):e60447
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Disease progression and neuroscience.
Nick Holford
J Pharmacokinet Pharmacodyn 2013 Apr;
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Dopamine dysregulation syndrome in Parkinson's disease: from clinical and neuropsychological characterisation to management and long-term outcome.
Roberto Cilia, Chiara Siri, Margherita Canesi, Anna Lena Zecchinelli, Danilo De Gaspari, Francesca Natuzzi, Silvana Tesei, Nicoletta Meucci, Claudio Bruno Mariani, Giorgio Sacilotto, Michela Zini, Claudio Ruffmann, Gianni Pezzoli
J Neurol Neurosurg Psychiatry 2013 Apr;
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New insights into the mechanism of drug-induced dyskinesia.
Anton J M Loonen, Svetlana A Ivanova
CNS Spectr 2013 Feb; 18(1):15-20
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Long-term safety and efficacy of preladenant in subjects with fluctuating Parkinson's disease.
Stewart A Factor, Kenneth Wolski, Daniel M Togasaki, Susan Huyck, Marc Cantillon, T W Ho, Robert A Hauser, Emmanuelle Pourcher
Mov Disord 2013 Apr;
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Impact of sub-thalamic nucleus deep brain stimulation on dual tasking gait in Parkinson's disease.
Eliraz Seri-Fainshtat, Zvi Israel, Aner Weiss, Jeffrey M Hausdorff
J Neuroeng Rehabil 2013 Apr; 10(1):38
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Role of oxidative stress in Parkinson's disease.
Onyou Hwang
Exp Neurobiol 2013 Mar; 22(1):11-7
PMID: Object id #8123585717 [PubMed - as supplied by publisher]

Multi target neuroprotective and neurorestorative anti-Parkinson and anti-Alzheimer drugs ladostigil and m30 derived from rasagiline.
Moussa B H Youdim
Exp Neurobiol 2013 Mar; 22(1):1-10
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Bilateral globus pallidus internus deep brain stimulation after bilateral pallidotomy in a patient with generalized early-onset primary dystonia.
Olga Waln, Joseph Jankovic
Mov Disord 2013 Apr;
PMID: Object id #273623580321 [PubMed - as supplied by publisher]

Chronic depression as a model disease for cerebral aging.
Bettina H Bewernick, Thomas E Schlaepfer
Dialogues Clin Neurosci 2013 Mar; 15(1):77-85
PMID: Object id #278323576891 [PubMed - as supplied by publisher]