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Nrf2 Signaling Contributes to the Neuroprotective Effects of Urate against 6-OHDA Toxicity.

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PLoS One 2014 ; 9(6):e100286

Authors: Ning Zhang, Hai-Yang Shu, Tingting Huang, Qi-Lin Zhang, Da Li, Guan-Qun Zhang, Xiao-Yan Peng, Chun-Feng Liu, Wei-Feng Luo, Li-Fang Hu

Mounting evidence shows that urate may become a biomarker of Parkinson's disease (PD) diagnosis and prognosis and a neuroprotectant candidate for PD therapy. However, the cellular and molecular mechanisms underlying its neuroprotective actions remain poorly understood.

PMID: 24959672 [PubMed - as supplied by publisher]

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