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Featured Research

What can we learn by studying genetics and Parkinson's? PDF-funded researchers Drs. Mata and Zabetian share their progress six years after launching the first large-scale survey of PD genetics in Latin America.

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PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

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Nonmotor Symptoms in LRRK2 G2019S Associated Parkinson's Disease.
Carles Gaig, Dolores Vilas, Jon Infante, María Sierra, Inés García-Gorostiaga, Mariateresa Buongiorno, Mario Ezquerra, Maria José Martí, Francesc Valldeoriola, Miquel Aguilar, Matilde Calopa, Jorge Hernandez-Vara, Eduardo Tolosa
PLoS One 2014 ; 9(10):e108982
PMID: 25330404 [PubMed - as supplied by publisher]

Neural Substrates of Cognitive Subtypes in Parkinson's Disease: A 3-Year Longitudinal Study.
Yumiko Shoji, Yoshiyuki Nishio, Toru Baba, Makoto Uchiyama, Kayoko Yokoi, Toshiyuki Ishioka, Yoshiyuki Hosokai, Kazumi Hirayama, Hiroshi Fukuda, Masashi Aoki, Takafumi Hasegawa, Atsushi Takeda, Etsuro Mori
PLoS One 2014 ; 9(10):e110547
PMID: 25330390 [PubMed - as supplied by publisher]

Official Japanese Version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale: validation against the original English version.
Kenichi Kashihara, Tomoyoshi Kondo, Yoshikuni Mizuno, Seiji Kikuchi, Sadako Kuno, Kazuko Hasegawa, Nobutaka Hattori, Hideki Mochizuki, Hideo Mori, Miho Murata, Masahiro Nomoto, Ryosuke Takahashi, Atsushi Takeda, Yoshio Tsuboi, Yoshikazu Ugawa, Mitsutoshi Yamanmoto, Fusako Yokochi, Fumihito Yoshii, Glenn T Stebbins, Barbara C Tilley, Sheng Luo, Lu Wang, Nancy R LaPelle, Christopher G Goetz,
Mov Disord Clin Pract (Hoboken) 2014 Sep; 1(3):200-212
PMID: 25328906 [PubMed - as supplied by publisher]

Clinical evaluation of fatigue in Japanese patients with Parkinson's disease.
Kenichiro Tanaka, Kenji Wada-Isoe, Mikie Yamamoto, Shugo Tagashira, Yuki Tajiri, Satoko Nakashita, Kenji Nakashima
Brain Behav 2014 Sep; 4(5):643-9
PMID: 25328841 [PubMed - as supplied by publisher]

Deep brain stimulation for the treatment of childhood dystonic cerebral palsy.
Joseph R Keen, Allison Przekop, Joffre E Olaya, Alexander Zouros, Frank P K Hsu
J Neurosurg Pediatr 2014 Oct; :1-9
PMID: 25325412 [PubMed - as supplied by publisher]

Reports of Pathological Gambling, Hypersexuality, and Compulsive Shopping Associated With Dopamine Receptor Agonist Drugs.
Thomas J Moore, Joseph Glenmullen, Donald R Mattison
JAMA Intern Med 2014 Oct;
PMID: 25329919 [PubMed - as supplied by publisher]

New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease.
H Karasawa, C Pietra, C Giuliano, S Garcia-Rubio, X Xu, S Yakabi, Y Taché, L Wang
Neurogastroenterol Motil 2014 Oct;
PMID: 25327342 [PubMed - as supplied by publisher]

Sparing of orexin-A and orexin-B neurons in the hypothalamus and of orexin fibers in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated macaques.
Manale Bensaid, Dominique Tandé, Véronique Fabre, Patrick P Michel, Etienne C Hirsch, Chantal François
Eur J Neurosci 2014 Oct;
PMID: 25328140 [PubMed - as supplied by publisher]

Chemoproteomics Demonstrates Target Engagement and Exquisite Selectivity of the Clinical Phosphodiesterase 10A Inhibitor MP-10 in Its Native Environment.
Jan-Philip Schülke, Laura A McAllister, Kieran F Geoghegan, Vinod Parikh, Thomas A Chappie, Patrick R Verhoest, Christopher J Schmidt, Douglas S Johnson, Nicholas J Brandon
ACS Chem Biol 2014 Oct;
PMID: 25295858 [PubMed - as supplied by publisher]

Disease Penetrance of Late-Onset Parkinsonism: A Meta-analysis.
Joanne Trinh, Ilaria Guella, Matthew James Farrer
JAMA Neurol 2014 Oct;
PMID: 25330418 [PubMed - as supplied by publisher]

Families with Wilson's disease in subsequent generations: Clinical and genetic analysis.
Karolina Dzie?yc, Tomasz Litwin, Grzegorz Chabik, Karolina Gramza, Anna Cz?onkowska
Mov Disord 2014 Oct;
PMID: 25327413 [PubMed - as supplied by publisher]

Mind matters: placebo enhances reward learning in Parkinson's disease.
Liane Schmidt, Erin Kendall Braun, Tor D Wager, Daphna Shohamy
Nat Neurosci 2014 Oct;
PMID: 25326691 [PubMed - as supplied by publisher]

A variety of pesticides trigger in vitro ?-synuclein accumulation, a key event in Parkinson's disease.
Areski Chorfa, Corinne Lazizzera, Dominique Bétemps, Eric Morignat, Sébastien Dussurgey, Thibault Andrieu, Thierry Baron
Arch Toxicol 2014 Oct;
PMID: 25326819 [PubMed - as supplied by publisher]

Protective Effects of Poly (butyl) Cyanoacrylate Nanoparticles Containing Vasoactive Intestinal Peptide Against 6-Hydroxydopamine-Induced Neurotoxicity In Vitro.
Zhi-Ran Xu, Wu-Fang Wang, Xin-Fang Liang, Ze-Hua Liu, Yu Liu, Liang Lin, Xuan Zhu
J Mol Neurosci 2014 Oct;
PMID: 25326789 [PubMed - as supplied by publisher]

Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease.
Jessie Theuns, Aline Verstraeten, Kristel Sleegers, Eline Wauters, Ilse Gijselinck, Stefanie Smolders, David Crosiers, Ellen Corsmit, Ellen Elinck, Manu Sharma, Rejko Krüger, Suzanne Lesage, Alexis Brice, Sun Ju Chung, Mi-Jung Kim, Young Jin Kim, Owen A Ross, Zbigniew K Wszolek, Ekaterina Rogaeva, Zhengrui Xi, Anthony E Lang, Christine Klein, Anne Weissbach, George D Mellick, Peter A Silburn, Georgios M Hadjigeorgiou, Efthimios Dardiotis, Nobutaka Hattori, Kotaro Ogaki, Eng-King Tan, Yi Zhao, Jan Aasly, Enza Maria Valente, Simona Petrucci, Grazia Annesi, Aldo Quattrone, Carlo Ferrarese, Laura Brighina, Angela Deutschländer, Andreas Puschmann, Christer Nilsson, Gaëtan Garraux, Mark S LeDoux, Ronald F Pfeiffer, Magdalena Boczarska-Jedynak, Grzegorz Opala, Demetrius M Maraganore, Sebastiaan Engelborghs, Peter Paul De Deyn, Patrick Cras, Marc Cruts, Christine Van Broeckhoven,
Neurology 2014 Oct;
PMID: 25326098 [PubMed - as supplied by publisher]

?-Synuclein forms non-selective cation channels and stimulates KATP channels in hippocampal neurons.
Sergej L Mironov
J Physiol 2014 Oct;
PMID: 25326450 [PubMed - as supplied by publisher]

Altered synaptic architecture and glycosylated synaptomatrix composition in a Drosophila classic galactosemia disease model.
Patricia Jumbo-Lucioni, William Parkinson, Kendal Broadie
Dis Model Mech 2014 Oct;
PMID: 25326312 [PubMed - as supplied by publisher]

A new split-GFP-based probe reveals DJ-1 translocation into the mitochondrial matrix to sustain ATP synthesis upon nutrient deprivation.
Tito Calě, Denis Ottolini, Maria Eugenia Soriano, Marisa Brini
Hum Mol Genet 2014 Oct;
PMID: 25305074 [PubMed - as supplied by publisher]

A platelet protein biochip rapidly detects an Alzheimer's disease-specific phenotype.
Michael Veitinger, Rudolf Oehler, Ellen Umlauf, Roland Baumgartner, Georg Schmidt, Christopher Gerner, Rita Babeluk, Johannes Attems, Goran Mitulovic, Eduard Rappold, John Lamont, Maria Zellner
Acta Neuropathol 2014 Nov; 128(5):665-77
PMID: 25248508 [PubMed - as supplied by publisher]

miRNAs as novel therapeutic targets and diagnostic biomarkers for Parkinson's disease: a patent evaluation of WO2014018650.
Marlen Hesse, Christoph Arenz
Expert Opin Ther Pat 2014 Nov; 24(11):1271-6
PMID: 25307171 [PubMed - as supplied by publisher]

Antidepressants Increase REM Sleep Muscle Tone in Patients with and without REM Sleep Behavior Disorder.
Stuart J McCarter, Erik K St Louis, David J Sandness, Katlyn Arndt, Maia Erickson, Grace Tabatabai, Bradley F Boeve, Michael H Silber
Sleep 2014 Oct;
PMID: 25325487 [PubMed - as supplied by publisher]

Dysautonomia in narcolepsy: evidence by questionnaire assessment.
Gilles Klein, Lothar Burghaus, Michel Vaillant, Vannina Pieri, Gereon R Fink, Nico Diederich
J Clin Neurol 2014 Oct; 10(4):314-9
PMID: 25324880 [PubMed - as supplied by publisher]

Hyperhomocysteinemia and neurologic disorders: a review.
Ramin Ansari, Ali Mahta, Eric Mallack, Jin Jun Luo
J Clin Neurol 2014 Oct; 10(4):281-8
PMID: 25324876 [PubMed - as supplied by publisher]

Potential of caveolae in the therapy of cardiovascular and neurological diseases.
Gemma Navarro, Dasiel O Borroto-Escuela, Kjell Fuxe, Rafael Franco
Front Physiol 2014 ; 5:370
PMID: 25324780 [PubMed - as supplied by publisher]

Spontaneous locomotor activity and L-DOPA-induced dyskinesia are not linked in 6-OHDA parkinsonian rats.
Stefania Sgroi, Alain Kaelin-Lang, Christine Capper-Loup
Front Behav Neurosci 2014 ; 8:331
PMID: 25324746 [PubMed - as supplied by publisher]

In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil: Dosimetry, Biodistribution, and Kinetic Analyses.
Trine Gjerlřff, Steen Jakobsen, Adjmal Nahimi, Ole L Munk, Dirk Bender, Aage K O Alstrup, Karina H Vase, Sřren B Hansen, David J Brooks, Per Borghammer
J Nucl Med 2014 Oct;
PMID: 25324520 [PubMed - as supplied by publisher]

Clozapine serum concentrations in dopamimetic psychosis in Parkinson's disease and related disorders.
Ulrich C Lutz, Ahmad Sirfy, Gerlinde Wiatr, Danuta Altpaß, Gisbert Farger, Thomas Gasser, Kathrin N Karle, Anil Batra
Eur J Clin Pharmacol 2014 Oct;
PMID: 25323805 [PubMed - as supplied by publisher]

Nobiletin Protects Dopaminergic Neurons in the 1-Methyl-4-Phenylpyridinium-Treated Rat Model of Parkinson's Disease.
Kyoung Hoon Jeong, Min-Tae Jeon, Heung Deok Kim, Un Ju Jung, Min Cheol Jang, Jin Woo Chu, Seung Jun Yang, Il Yoon Choi, Myung-Sook Choi, Sang Ryong Kim
J Med Food 2014 Oct;
PMID: 25325362 [PubMed - as supplied by publisher]

Rasagiline: A Review of Its Use in the Treatment of Idiopathic Parkinson's Disease.
Paul L McCormack
CNS Drugs 2014 Oct;
PMID: 25322951 [PubMed - as supplied by publisher]

Effects of cannabidiol in the treatment of patients with Parkinson's disease: An exploratory double-blind trial.
Marcos Hortes N Chagas, Antonio W Zuardi, Vitor Tumas, Márcio Alexandre Pena-Pereira, Emmanuelle T Sobreira, Mateus M Bergamaschi, Antonio Carlos Dos Santos, Antonio Lucio Teixeira, Jaime Ec Hallak, José Alexandre S Crippa
J Psychopharmacol 2014 Nov; 28(11):1088-98
PMID: 25237116 [PubMed - as supplied by publisher]

RTP801/REDD1: a stress coping regulator that turns into a troublemaker in neurodegenerative disorders.
Mercč Canal, Joan Romaní-Aumedes, Núria Martín-Flores, Víctor Pérez-Fernández, Cristina Malagelada
Front Cell Neurosci 2014 ; 8:313
PMID: 25324725 [PubMed - as supplied by publisher]

Parkinson Disease Genetics: A "Continuum" From Mendelian to Multifactorial Inheritance.
S Petrucci, F Consoli, E M Valente
Curr Mol Med 2014 Oct;
PMID: 25323865 [PubMed - as supplied by publisher]

Rho Kinase and Dopaminergic Degeneration: A Promising Therapeutic Target for Parkinson's Disease.
Jose L Labandeira-Garcia, Ana I Rodríguez-Perez, Begońa Villar-Cheda, Ana Borrajo, Antonio Dominguez-Meijide, Maria J Guerra
Neuroscientist 2014 Oct;
PMID: 25323761 [PubMed - as supplied by publisher]

Protective effects of PEP-1-Catalase on stress-induced cellular toxicity and MPTP-induced Parkinson's disease.
Seon Ae Eom, Dae Won Kim, Min Jea Shin, Eun Hee Ahn, Seok Young Chung, Eun Jeong Sohn, Hyo Sang Jo, Su-Jeong Jeon, Duk-Soo Kim, Hyeok Yil Kwon, Sung-Woo Cho, Kyu Hyung Han, Jinseu Park, Won Sik Eum, Soo Young Choi
BMB Rep 2014 Oct;
PMID: 25322954 [PubMed - as supplied by publisher]

Applications of digital holographic microscopy in therapeutic evaluation of Chinese herbal medicines.
Chung-Hsin Wu, Xin-Ji Lai, Chau-Jern Cheng, Yu-Chen Yu, Chun-Yen Chang
Appl Opt 2014 Sep; 53(27):G192-7
PMID: 25322130 [PubMed - as supplied by publisher]

Effects of dopamine uptake inhibitor MRZ-9547 in animal models of Parkinson's disease.
Andrzej Dekundy, Flora Mela, Martine Hofmann, Wojciech Danysz
J Neural Transm 2014 Oct;
PMID: 25319446 [PubMed - as supplied by publisher]

The major impact of freezing of gait on quality of life in Parkinson's disease.
Courtney C Walton, James M Shine, Julie M Hall, Claire O'Callaghan, Loren Mowszowski, Moran Gilat, Jennifer Y Y Szeto, Sharon L Naismith, Simon J G Lewis
J Neurol 2014 Oct;
PMID: 25319020 [PubMed - as supplied by publisher]

New treatments for the motor symptoms of Parkinson's disease.
Anne-Catherine Vijverman, Susan H Fox
Expert Rev Clin Pharmacol 2014 Nov; 7(6):761-77
PMID: 25318835 [PubMed - as supplied by publisher]

Quantitative gait analysis in patients with parkinson treated with deep brain stimulation: The effects of a robotic gait training.
Alice Nardo, Federica Anasetti, Domenico Servello, Mauro Porta
NeuroRehabilitation 2014 Oct;
PMID: 25318782 [PubMed - as supplied by publisher]

Effects of an adapted physical activity program on motor and non-motor functions and quality of life in patients with parkinson's disease.
Lucia Cugusi, Paolo Solla, Francesca Zedda, Martina Loi, Roberto Serpe, Antonino Cannas, Francesco Marrosu, Giuseppe Mercuro
NeuroRehabilitation 2014 Oct;
PMID: 25318771 [PubMed - as supplied by publisher]

Regulation of a heart rhythm in mouse with asymptomatic and symptomatic models of Parkinson's disease].
Patol Fiziol Eksp Ter 2014 Apr-Jun; (2):33-6
PMID: 25318160 [PubMed - as supplied by publisher]

Assessment of cerebral iron content in patients with Parkinson's disease by the susceptibility-weighted MRI.
S-F Wu, Z-F Zhu, Y Kong, H-P Zhang, G-Q Zhou, Q-T Jiang, X-P Meng
Eur Rev Med Pharmacol Sci 2014 Sep; 18(18):2605-8
PMID: 25317792 [PubMed - as supplied by publisher]

Safinamide for the treatment of Parkinson's disease.
Rukmini Mridula Kandadai, Shaik Afshan Jabeen, Meena A Kanikannan, Rupam Borgohain
Expert Rev Clin Pharmacol 2014 Nov; 7(6):747-59
PMID: 25300164 [PubMed - as supplied by publisher]

Efficient modification of alpha-synuclein Serine 129 by protein kinase CK1 requires phosphorylation of Tyrosine 125 as a priming event.
Jonas Kosten, Andres Binolfi, Marchel Stuiver, Silvia Verzini, François-Xavier Theillet, Beata Bekei, Marleen van Rossum, Philipp Selenko
ACS Chem Neurosci 2014 Oct;
PMID: 25320964 [PubMed - as supplied by publisher]

?-Synuclein-induced mitochondrial dysfunction in isolated preparation and intact cells: Implications in the pathogenesis of Parkinson's disease.
Aritri Bir, Oishimaya Sen, Shruti Anand, Vineet Kumar Khemka, Priyanjalee Banerjee, Roberto Cappai, Arghyadip Sahoo, Sasanka Chakrabarti
J Neurochem 2014 Oct;
PMID: 25319443 [PubMed - as supplied by publisher]

A role for the Parkinson's disease protein DJ-1 as a chaperone and antioxidant in the anhydrobiotic nematode Panagrolaimus superbus.
Bridget A Culleton, Patrick Lall, Gemma K Kinsella, Sean Doyle, John McCaffrey, David A Fitzpatrick, Ann M Burnell
Cell Stress Chaperones 2014 Oct;
PMID: 25318690 [PubMed - as supplied by publisher]

Visuomotor control of neck surface electromyography in Parkinson's disease.
Jessica R Malloy, Juliana C Valentin, Gabrielle L Hands, Christina A Stevens, Susan E Langmore, J Pieter Noordzij, Cara E Stepp
NeuroRehabilitation 2014 Oct;
PMID: 25318778 [PubMed - as supplied by publisher]

Neuroprotective effects of berry fruits on neurodegenerative diseases.
Selvaraju Subash, Musthafa Mohamed Essa, Samir Al-Adawi, Mushtaq A Memon, Thamilarasan Manivasagam, Mohammed Akbar
Neural Regen Res 2014 Aug; 9(16):1557-66
PMID: 25317174 [PubMed - as supplied by publisher]

AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: Identification, SAR and pharmacological characterization.
Ivo Vranesic, Silvio Ofner, Peter Josef Flor, Graeme Bilbe, Rochdi Bouhelal, Albert Enz, Sandrine Desrayaud, Kevin McAllister, Rainer Kuhn, Fabrizio Gasparini
Bioorg Med Chem 2014 Sep;
PMID: 25316499 [PubMed - as supplied by publisher]

Managing depression in Parkinson's patients: risk factors and clinical pearls.
Rachel Biemiller, Irene Hegeman Richard
Neurodegener Dis Manag 2014 Aug; 4(4):329-36
PMID: 25313989 [PubMed - as supplied by publisher]

Prognostic significance of weight changes in Parkinson's disease: the Park-weight phenotype.
Jagdish C Sharma, Michael Vassallo
Neurodegener Dis Manag 2014 Aug; 4(4):309-16
PMID: 25313987 [PubMed - as supplied by publisher]

Neuroradiology, Anesthesia, Bioengineering, and Hardware Programming in the Clinical Applications of Deep Brain Stimulation.
Ayden Jacob, Krishnan Chakravarthy
Cureus 2014 Apr; 6(4)
PMID: 25298923 [PubMed - as supplied by publisher]

Nitric oxide synthase inhibition decreases l-DOPA-induced dyskinesia and the expression of striatal molecular markers in Pitx3(-/-) aphakia mice.
Oscar Solís, Isabel Espadas, Elaine A Del-Bel, Rosario Moratalla
Neurobiol Dis 2014 Sep; 73C:49-59
PMID: 25281315 [PubMed - as supplied by publisher]

Resting-state networks link invasive and noninvasive brain stimulation across diverse psychiatric and neurological diseases.
Michael D Fox, Randy L Buckner, Hesheng Liu, M Mallar Chakravarty, Andres M Lozano, Alvaro Pascual-Leone
Proc Natl Acad Sci U S A 2014 Oct; 111(41):E4367-75
PMID: 25267639 [PubMed - as supplied by publisher]

Effects of naringin, a flavanone glycoside in grapefruits and citrus fruits, on the nigrostriatal dopaminergic projection in the adult brain.
Un Ju Jung, Sang Ryong Kim
Neural Regen Res 2014 Aug; 9(16):1514-7
PMID: 25317167 [PubMed - as supplied by publisher]

Driving neural regeneration through the mammalian target of rapamycin.
Kenneth Maiese
Neural Regen Res 2014 Aug; 9(15):1413-7
PMID: 25317149 [PubMed - as supplied by publisher]

PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper.
Asad A Aboud, Andrew M Tidball, Kevin K Kumar, M Diana Neely, Bingying Han, Kevin C Ess, Charles C Hong, Keith M Erikson, Peter Hedera, Aaron B Bowman
Neurobiol Dis 2014 Oct;
PMID: 25315681 [PubMed - as supplied by publisher]

Efficacy of Bisphosphonates against Hip Fracture in Elderly Patients with Stroke and Parkinson Diseases: Meta-analysis of Randomized Controlled Trials.
Weiwei Zhang, Chen Zhu, Mengwen Sun, Yuhao Ge, Guang Yan
J Stroke Cerebrovasc Dis 2014 Oct;
PMID: 25314942 [PubMed - as supplied by publisher]

The potential of alternate sources of cells for neural grafting in Parkinson's and Huntington's disease.
Janelle Drouin-Ouellet
Neurodegener Dis Manag 2014 Aug; 4(4):297-307
PMID: 25313986 [PubMed - as supplied by publisher]

(1)H NMR-based metabolomics study on a goldfish model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Zhaoguang Lu, Junsong Wang, Minghui Li, Qingwang Liu, Dandan Wei, Minghua Yang, Lingyi Kong
Chem Biol Interact 2014 Sep; 223C:18-26
PMID: 25242684 [PubMed - as supplied by publisher]

Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor inhibit ferrous iron influx via divalent metal transporter 1 and iron regulatory protein 1 regulation in ventral mesencephalic neurons.
Hao-Yun Zhang, Ning Song, Hong Jiang, Ming-Xia Bi, Jun-Xia Xie
Biochim Biophys Acta 2014 Dec; 1843(12):2967-75
PMID: 25239763 [PubMed - as supplied by publisher]

Climate change and infectious diseases in the Arctic: establishment of a circumpolar working group.
Alan J Parkinson, Birgitta Evengard, Jan C Semenza, Nicholas Ogden, Malene L Břrresen, Jim Berner, Michael Brubaker, Anders Sjöstedt, Magnus Evander, David M Hondula, Bettina Menne, Natalia Pshenichnaya, Prabhu Gounder, Tricia Larose, Boris Revich, Karsten Hueffer, Ann Albihn
Int J Circumpolar Health 2014 ; 73
PMID: 25317383 [PubMed - as supplied by publisher]

The role of DJ-1 in the oxidative stress cell death cascade after stroke.
Paolina Pantcheva, Maya Elias, Kelsey Duncan, Cesar V Borlongan, Naoki Tajiri, Yuji Kaneko
Neural Regen Res 2014 Aug; 9(15):1430-3
PMID: 25317153 [PubMed - as supplied by publisher]

LIMP-2 expression is critical for ?-glucocerebrosidase activity and ?-synuclein clearance.
Michelle Rothaug, Friederike Zunke, Joseph R Mazzulli, Michaela Schweizer, Hermann Altmeppen, Renate Lüllmann-Rauch, Wouter W Kallemeijn, Paulo Gaspar, Johannes M Aerts, Markus Glatzel, Paul Saftig, Dimitri Krainc, Michael Schwake, Judith Blanz
Proc Natl Acad Sci U S A 2014 Oct;
PMID: 25316793 [PubMed - as supplied by publisher]

Repression of rRNA transcription by PARIS contributes to Parkinson's Disease.
Hojin Kang, Joo-Ho Shin
Neurobiol Dis 2014 Oct;
PMID: 25315684 [PubMed - as supplied by publisher]

Brain iron accumulation exacerbates the pathogenesis of MPTP-induced Parkinson's disease.
L-H You, F Li, L Wang, S-E Zhao, S-M Wang, L-L Zhang, L-H Zhang, X-L Duan, P Yu, Y-Z Chang
Neuroscience 2014 Oct;
PMID: 25301748 [PubMed - as supplied by publisher]

Treadmill exercise activates Nrf2 antioxidant system to protect the nigrostriatal dopaminergic neurons from MPP(+) toxicity.
Yi-Hsien Tsou, Ching-Ting Shih, Cheng-Hsin Ching, Jui-Yen Huang, Chauying J Jen, Lung Yu, Yu-Min Kuo, Fong-Sen Wu, Jih-Ing Chuang
Exp Neurol 2014 Oct; 263C:50-62
PMID: 25286336 [PubMed - as supplied by publisher]

Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis.
Alban Ordureau, Shireen A Sarraf, David M Duda, Jin-Mi Heo, Mark P Jedrychowski, Vladislav O Sviderskiy, Jennifer L Olszewski, James T Koerber, Tiao Xie, Sean A Beausoleil, James A Wells, Steven P Gygi, Brenda A Schulman, J Wade Harper
Mol Cell 2014 Oct;
PMID: 25284222 [PubMed - as supplied by publisher]

Revisiting the Roco G protein cycle.
Susanne Terheyden, Franz Y Ho, Bernd Karl Gilsbach, Alfred Wittinghofer, Arjan Kortholt
Biochem J 2014 Oct;
PMID: 25317655 [PubMed - as supplied by publisher]

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations.
Vinay K Godena, Nicholas Brookes-Hocking, Annekathrin Moller, Gary Shaw, Matthew Oswald, Rosa M Sancho, Christopher C J Miller, Alexander J Whitworth, Kurt J De Vos
Nat Commun 2014 ; 5:5245
PMID: 25316291 [PubMed - as supplied by publisher]

Could the detection of visual disturbances associated with Parkinson's disease genes in flies lead to new treatments for the disease?
Alex R Wade, Christopher Jh Elliott
Neurodegener Dis Manag 2014 Aug; 4(4):291-3
PMID: 25313984 [PubMed - as supplied by publisher]

Changes in actin dynamics and F-actin structure both in synaptoneurosomes of LRRK2(R1441G) mutant mice and in primary human fibroblasts of LRRK2(G2019S) mutation carriers.
M Caesar, S Felk, J O Aasly, F Gillardon
Neuroscience 2014 Oct;
PMID: 25301747 [PubMed - as supplied by publisher]

Pharmacogenetics of drug response in Parkinson's disease.
Eleonora D?olji?, Ivana Novakovi?, Maja Krajinovic, Ivan Grbatini?, Vladimir Kosti?
Int J Neurosci 2014 Oct;
PMID: 25226559 [PubMed - as supplied by publisher]

Serotonin Toxicity Association with Concomitant Antidepressants and Rasagiline Treatment: Retrospective Study (STACCATO).
Michel Panisset, Jack J Chen, Sean H Rhyee, Jill Conner, Julie Mathena,
Pharmacotherapy 2014 Oct;
PMID: 25314256 [PubMed - as supplied by publisher]

Metacognitions, anxiety, and distress related to motor fluctuations in Parkinson's disease.
Richard G Brown, Bruce A Fernie
J Psychosom Res 2014 Oct;
PMID: 25311871 [PubMed - as supplied by publisher]

Side and Type of Initial Motor Symptom Influences Visuospatial Functioning in Parkinson's Disease.
Daniel R Seichepine, Sandy Neargarder, Sigurros Davidsdottir, Gretchen O Reynolds, Alice Cronin-Golomb
J Parkinsons Dis 2014 Oct;
PMID: 25311203 [PubMed - as supplied by publisher]

Validation of an Ambulatory Capacity Measure in Parkinson Disease: A Construct Derived from the Unified Parkinson's Disease Rating Scale.
Sotirios A Parashos, Jordan Elm, James T Boyd, Kelvin L Chou, Lin Dai, Zoltan Mari, John C Morgan, Lewis Sudarsky, Catherine L Wielinski
J Parkinsons Dis 2014 Oct;
PMID: 25311202 [PubMed - as supplied by publisher]

Lewy body disease and dementia with Lewy bodies.
Kenji Kosaka
Proc Jpn Acad Ser B Phys Biol Sci 2014 ; 90(8):301-6
PMID: 25311140 [PubMed - as supplied by publisher]

GABA-mediated changes in inter-hemispheric beta frequency activity in early-stage Parkinson's disease.
S D Hall, E J Prokic, C J McAllister, K C Ronnqvist, A C Williams, N Yamawaki, C Witton, G L Woodhall, I M Stanford
Neuroscience 2014 Sep; 281C:68-76
PMID: 25261686 [PubMed - as supplied by publisher]

Parkinson's disease in the limelight.
A I Graul, S Kamerkar
Drugs Today (Barc) 2014 Sep; 50(9):641-5
PMID: 25313370 [PubMed - as supplied by publisher]

Clinical applications involving CNS gene transfer.
Boris Kantor, Thomas McCown, Paola Leone, Steven J Gray
Adv Genet 2014 ; 87:71-124
PMID: 25311921 [PubMed - as supplied by publisher]

Guanosine Protects Glial Cells Against 6-Hydroxydopamine Toxicity.
Patricia Giuliani, Patrizia Ballerini, Silvana Buccella, Renata Ciccarelli, Michel P Rathbone, Silvia Romano, Iolanda D'Alimonte, Francesco Caciagli, Patrizia Di Iorio, Mieczyslaw Pokorski
Adv Exp Med Biol 2014 Oct;
PMID: 25310956 [PubMed - as supplied by publisher]

Local control of the host immune response performed with mesenchymal stem cells: perspectives for functional intracerebral xenotransplantation.
Xavier Lévęque, Elodie Mathieux, Véronique Nerričre-Daguin, Reynald Thinard, Laetitia Kermarrec, Tony Durand, Thomas Haudebourg, Bernard Vanhove, Laurent Lescaudron, Isabelle Neveu, Philippe Naveilhan
J Cell Mol Med 2014 Oct;
PMID: 25310920 [PubMed - as supplied by publisher]

Mesenchymal stem cells: potential in treatment of neurodegenerative diseases.
Tanmay Tanna, Vatsal Sachan
Curr Stem Cell Res Ther 2014 ; 9(6):513-21
PMID: 25248677 [PubMed - as supplied by publisher]

Discovery of 3-Arylcoumarin-tetracyclic Tacrine Hybrids as Multifunctional Agents against Parkinson's Disease.
Koneni V Sashidhara, Ram K Modukuri, Pooja Jadiya, K Bhaskara Rao, Tanuj Sharma, Rizwanul Haque, Deependra Kumar Singh, Dibyendu Banerjee, Mohammad Imran Siddiqi, Aamir Nazir
ACS Med Chem Lett 2014 Oct; 5(10):1099-103
PMID: 25313319 [PubMed - as supplied by publisher]

The key role of sphingosine kinases in the molecular mechanism of neuronal cell survival and death in an experimental model of Parkinson's disease.
Ja Pyszko, Jb Strosznajder
Folia Neuropathol 2014 ; 52(3):260-9
PMID: 25310737 [PubMed - as supplied by publisher]

Treadmill training improves overground walking economy in Parkinson's disease: a randomized, controlled pilot study.
Miguel Angel Fernández-Del-Olmo, Jose Andres Sanchez, Olalla Bello, Virginia Lopez-Alonso, Gonzalo Márquez, Luis Morenilla, Xabier Castro, Manolo Giraldez, Diego Santos-García
Front Neurol 2014 ; 5:191
PMID: 25309510 [PubMed - as supplied by publisher]

Influence of depressive symptoms on dopaminergic treatment of Parkinson's disease.
Alexandru Hanganu, Clotilde Degroot, Oury Monchi, Christophe Bedetti, Béatriz Mejia-Constain, Anne-Louise Lafontaine, Sylvain Chouinard, Marie-Andrée Bruneau
Front Neurol 2014 ; 5:188
PMID: 25309508 [PubMed - as supplied by publisher]

Long-range correlation properties in timing of skilled piano performance: the influence of auditory feedback and deep brain stimulation.
María Herrojo Ruiz, Sang Bin Hong, Holger Hennig, Eckart Altenmüller, Andrea A Kühn
Front Psychol 2014 ; 5:1030
PMID: 25309487 [PubMed - as supplied by publisher]

Attentional Set-Shifting in Parkinson's Disease Patients with Freezing of Gait-Acquisition and Discrimination Set Learning Deficits at the Background?
Elka Stefanova, Milica Je?menica Luki?, Ljubomir Ziropadja, Vladana Markovi?, Tanja Stojkovi?, Aleksandra Tomi?, Nata?a Draga?evi? Mi?kovi?, Vladimir Kosti?
J Int Neuropsychol Soc 2014 Oct; :1-8
PMID: 25307410 [PubMed - as supplied by publisher]

A Genetic Mouse Model of Parkinson's Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine.
N Brehm, F Bez, T Carlsson, B Kern, S Gispert, G Auburger, M A Cenci
Mol Neurobiol 2014 Oct;
PMID: 25307288 [PubMed - as supplied by publisher]

"Masters and servants" in parkinsonian gait: a three-dimensional analysis of biomechanical changes sensitive to disease progression.
G Albani, V Cimolin, A Fasano, C Trotti, M Galli, A Mauro
Funct Neurol 2014 Apr-Jun; 29(2):99-105
PMID: 25306119 [PubMed - as supplied by publisher]

What happens to microglial TREM2 in Alzheimer's disease: Immunoregulatory turned into immunopathogenic?
L-F Lue, C Schmitz, D G Walker
Neuroscience 2014 Oct;
PMID: 25281879 [PubMed - as supplied by publisher]

Physical training prevents depressive symptoms and a decrease in brain-derived neurotrophic factor in Parkinson's disease.
T Tuon, S S Valvassori, G C Dal Pont, C S Paganini, B G Pozzi, T F Luciano, P S Souza, J Quevedo, C T Souza, R A Pinho
Brain Res Bull 2014 Sep; 108C:106-112
PMID: 25264157 [PubMed - as supplied by publisher]

Human Wharton?s jelly-derived stem cells display immunomodulatory properties and transiently improve rat experimental autoimmune encephalomyelitis.
Raf Donders, Marjan Vanheusden, Jeroen Fj Bogie, Stylianos Ravanidis, Kristof Thewissen, Piet Stinissen, Wilfried Gyselaers, Jerome Ja Hendriks, Niels Hellings
Cell Transplant 2014 Oct;
PMID: 25310756 [PubMed - as supplied by publisher]

Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases.
S N Pchelina, E P Nuzhnyi, A K Emelyanov, T M Boukina, T S Usenko, M A Nikolaev, G N Salogub, A F Yakimovskii, E Yu Zakharova
Neurosci Lett 2014 Sep; 583C:188-193
PMID: 25265039 [PubMed - as supplied by publisher]

Elevated levels of cerebrospinal fluid ?-synuclein oligomers in healthy asymptomatic LRRK2 mutation carriers.
Jan O Aasly, Krisztina K Johansen, Gunnar Brřnstad, Bjřrg J Warř, Nour K Majbour, Shiji Varghese, Fatimah Alzahmi, Katerina E Paleologou, Dena A M Amer, Abdulmonem Al-Hayani, Omar M A El-Agnaf
Front Aging Neurosci 2014 ; 6:248
PMID: 25309429 [PubMed - as supplied by publisher]

Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease.
Lars Tönges, Eva M Szegö, Patrizia Hause, Kim-Ann Saal, Lars Tatenhorst, Jan Christoph Koch, Zara D Hedouville, Vivian Dambeck, Sebastian Kügler, Christoph P Dohm, Mathias Bähr, Paul Lingor
Front Aging Neurosci 2014 ; 6:239
PMID: 25309425 [PubMed - as supplied by publisher]

Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice.
Dayne A Beccano-Kelly, Naila Kuhlmann, Igor Tatarnikov, Mattia Volta, Lise N Munsie, Patrick Chou, Li-Ping Cao, Heather Han, Lucia Tapia, Matthew J Farrer, Austen J Milnerwood
Front Cell Neurosci 2014 ; 8:301
PMID: 25309331 [PubMed - as supplied by publisher]

An association study between Heme oxygenase-1 genetic variants and Parkinson's disease.
Pedro Ayuso, Carmen Martínez, Pau Pastor, Oswaldo Lorenzo-Betancor, Antonio Luengo, Félix J Jiménez-Jiménez, Hortensia Alonso-Navarro, José A G Agúndez, Elena García-Martín
Front Cell Neurosci 2014 ; 8:298
PMID: 25309329 [PubMed - as supplied by publisher]

Edible bird's nest ameliorates oxidative stress-induced apoptosis in SH-SY5Y human neuroblastoma cells.
Mei Yeng Yew, Rhun Yian Koh, Soi Moi Chye, Iekhsan Othman, Khuen Yen Ng
BMC Complement Altern Med 2014 Oct; 14(1):391
PMID: 25308934 [PubMed - as supplied by publisher]

Neuroprotective and antidepressant-like effects of melatonin in a rotenone-induced Parkinson's disease model in rats.
Taysa B Bassani, Raisa W Gradowski, Tiago Zaminelli, Janaína K Barbiero, Ronise M Santiago, Suelen L Boschen, Claudio da Cunha, Marcelo M S Lima, Roberto Andreatini, Maria A B F Vital
Brain Res 2014 Oct;
PMID: 25301688 [PubMed - as supplied by publisher]

The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease.
J Schapansky, J D Nardozzi, M J LaVoie
Neuroscience 2014 Oct;
PMID: 25284317 [PubMed - as supplied by publisher]

Induction of Pi Form of Glutathione S-Transferase by Carnosic Acid Is Mediated through PI3K/Akt/NF-?B Pathway and Protects against Neurotoxicity.
Chia-Yuan Lin, Jing-Hsien Chen, Ru-Huei Fu, Chia-Wen Tsai
Chem Res Toxicol 2014 Oct;
PMID: 25271104 [PubMed - as supplied by publisher]

A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic mouse model of Parkinson's disease.
Brian P Dranka, Alison Gifford, Donna McAllister, Jacek Zielonka, Joy Joseph, Crystal L O'Hara, Cheryl L Stucky, Anumantha G Kanthasamy, Balaraman Kalyanaraman
Neurosci Lett 2014 Sep; 583C:159-164
PMID: 25263790 [PubMed - as supplied by publisher]

Mitogen- and stress-activated protein kinase 1 is required for specific signaling responses in dopamine-denervated mouse striatum, but is not necessary for l-DOPA-induced dyskinesia.
Cristina Alcacer, Fanny Charbonnier-Beaupel, Jean-Christophe Corvol, Jean-Antoine Girault, Denis Hervé
Neurosci Lett 2014 Sep; 583C:76-80
PMID: 25233866 [PubMed - as supplied by publisher]

Construction of bicistronic lentiviral vectors for tracking the expression of CDNF in transduced cells.
Anllely Fernández, Sheyla Guzmán, Yocelin Cruz, Pedro Zamorano
Plasmid 2014 Sep; 76C:15-23
PMID: 25217797 [PubMed - as supplied by publisher]

The N170 and face perception in psychiatric and neurological disorders: A systematic review.
Daniel Feuerriegel, Owen Churches, Jessica Hofmann, Hannah A D Keage
Clin Neurophysiol 2014 Sep;
PMID: 25306210 [PubMed - as supplied by publisher]

Comparison of IPX066 with carbidopa-levodopa plus entacapone in advanced PD patients.
Fabrizio Stocchi, Ann Hsu, Sarita Khanna, Aaron Ellenbogen, Andreas Mahler, Grace Liang, Ulrich Dillmann, Robert Rubens, Sherron Kell, Suneel Gupta
Parkinsonism Relat Disord 2014 Aug;
PMID: 25306200 [PubMed - as supplied by publisher]

Dispositional optimism, depression, disability and quality of life in Parkinson's disease.
A Gison, V Dall'Armi, V Donati, F Rizza, S Giaquinto
Funct Neurol 2014 Apr/Jun; 29(2):113-119
PMID: 25306121 [PubMed - as supplied by publisher]

Neural correlates of progressive reduction of bradykinesia in de novo Parkinson's disease.
Eeksung Lee, Ji Eun Lee, Kwangsun Yoo, Jin Yong Hong, Jungsu Oh, Mun Kyung Sunwoo, Jae Seung Kim, Yong Jeong, Phil Hyu Lee, Young Ho Sohn, Suk Yun Kang
Parkinsonism Relat Disord 2014 Sep;
PMID: 25304859 [PubMed - as supplied by publisher]

Motor impairment, depression, dementia: Which forms the impression of disease severity in Parkinson's disease?
Oliver Riedel, Jens Klotsche, Hans-Ulrich Wittchen,
Parkinsonism Relat Disord 2014 Sep;
PMID: 25304858 [PubMed - as supplied by publisher]

Changes in olfaction during ageing and in certain neurodegenerative diseases: Up-to-date.
A-J Bianchi, H Guépet-Sordet, P Manckoundia
Rev Med Interne 2014 Oct;
PMID: 25304170 [PubMed - as supplied by publisher]

The sense-of-coherence predicts health-related quality of life and emotional distress but not disability in Parkinsonżs disease.
Annalisa Gison, Federica Rizza, Stefano Bonassi, Valentina Dall Armi, Stefania Lisi, Salvatore Giaquinto
BMC Neurol 2014 Oct; 14(1):193
PMID: 25304029 [PubMed - as supplied by publisher]

L-745,870 reduces the expression of abnormal involuntary movements in the 6-OHDA-lesioned rat.
Philippe Huot, Tom H Johnston, James B Koprich, Maria C Espinosa, Maria Gabriela Reyes, Susan H Fox, Jonathan M Brotchie
Behav Pharmacol 2014 Oct;
PMID: 25303957 [PubMed - as supplied by publisher]

New developments in the management of neurogenic orthostatic hypotension.
Italo Biaggioni
Curr Cardiol Rep 2014 Nov; 16(11):542
PMID: 25303896 [PubMed - as supplied by publisher]

Great expectations: the placebo effect in Parkinson's disease.
Sarah Christine Lidstone
Handb Exp Pharmacol 2014 ; 225:139-47
PMID: 25304530 [PubMed - as supplied by publisher]

Successful subthalamic nucleus deep brain stimulation therapy after significant lead displacement from a subdural hematoma.
Esmiralda Yeremeyeva Henderson, Timothy Goble, Pierre-François D'Haese, Srivatsan Pallavaram, Chima Oluigbo, Punit Agrawal, Milind Deogaonkar, Ali Rezai
J Clin Neurosci 2014 Oct;
PMID: 25304438 [PubMed - as supplied by publisher]

Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.
Qian Zhou, Chunxiao Liu, Wen Liu, Hai Zhang, Ruijie Zhang, Jia Liu, Jinfei Zhang, Chong Xu, Lei Liu, Shile Huang, Long Chen
Toxicol Sci 2014 Oct;
PMID: 25304210 [PubMed - as supplied by publisher]

Rab11 modulates ?-synuclein mediated defects in synaptic transmission and behaviour.
Carlo Breda, Marie L Nugent, Jasper G Estranero, Charalambos P Kyriacou, Tiago F Outeiro, Joern R Steinert, Flaviano Giorgini
Hum Mol Genet 2014 Oct;
PMID: 25305083 [PubMed - as supplied by publisher]

PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death.
Hyo-Kyoung Choi, Youngsok Choi, HeeBum Kang, Eun-Jin Lim, Soo-Yeon Park, Hyun-Seob Lee, Ji-Min Park, Jisook Moon, Yoon-Jung Kim, Insup Choi, Eun-Hye Joe, Kyung-Chul Choi, Ho-Geun Yoon
Hum Mol Genet 2014 Oct;
PMID: 25305081 [PubMed - as supplied by publisher]

A Nucleoprotein-Enriched Diet Suppresses Dopaminergic Neuronal Cell Loss and Motor Deficit in Mice with MPTP-Induced Parkinson's Disease.
Keisuke Kiriyama, Hirokazu Ohtaki, Natsuki Kobayashi, Norimitsu Murai, Minako Matsumoto, Shun Sasaki, Chika Sawa, Kazue Satoh, Masaji Matsunaga, Seiji Shioda
J Mol Neurosci 2014 Oct;
PMID: 25303858 [PubMed - as supplied by publisher]

Cell cycle regulation of DNA polymerase Beta in rotenone-based Parkinson's disease models.
Hongcai Wang, Yan Chen, Jinbo Chen, Zhentao Zhang, Wansheng Lao, Xizhi Li, Jinsha Huang, Tao Wang
PLoS One 2014 ; 9(10):e109697
PMID: 25303312 [PubMed - as supplied by publisher]

The possible mechanism of Parkinson's disease progressive damage and the preventive effect of GM1 in the rat model induced by 6-hydroxydopamine.
Renshi Xu, Yiyi Zhou, Xin Fang, Yi Lu, Jiao Li, Jie Zhang, Xia Deng, Shujuan Li
Brain Res 2014 Oct;
PMID: 25285892 [PubMed - as supplied by publisher]

Association of Microtubule associated protein tau/Saitohin (MAPT/STH) MAPT_238bp/STH Q7R polymorphisms and Parkinson's disease: A meta-analysis.
Shan-Shan Lu, Feng-Feng Gong, Fang Feng, Cai-Yun Hu, Zhen-Zhong Qian, Yi-Le Wu, Hui-Yun Yang, Ye-Huan Sun
Biochem Biophys Res Commun 2014 Oct;
PMID: 25305495 [PubMed - as supplied by publisher]

Epigenome-Wide Association Study for Parkinson's Disease.
Kerry Moore, Amy Jayne McKnight, David Craig, Francis O'Neill
Neuromolecular Med 2014 Oct;
PMID: 25304910 [PubMed - as supplied by publisher]

Identification of a set of endogenous reference genes for miRNA expression studies in Parkinson's disease blood samples.
Alice Serafin, Luisa Foco, Hagen Blankenburg, Anne Picard, Stefano Zanigni, Alessandra Zanon, Peter P Pramstaller, Andrew A Hicks, Christine Schwienbacher
BMC Res Notes 2014 Oct; 7(1):715
PMID: 25304816 [PubMed - as supplied by publisher]

The role of SNCA and MAPT in Parkinson disease and LRRK2 parkinsonism in the Tunisian Arab-Berber population.
J Trinh, E K Gustavsson, I Guella, C Vilarińo-Güell, D Evans, M Encarnacion, H Sherman, F Hentati, M J Farrer
Eur J Neurol 2014 Nov; 21(11):e91-2
PMID: 25303626 [PubMed - as supplied by publisher]

Magnetic Resonance Spectroscopy: An In Vivo Molecular Imaging Biomarker for Parkinson's Disease?
Rosella Ciurleo, Giuseppe Di Lorenzo, Placido Bramanti, Silvia Marino
Biomed Res Int 2014 ; 2014:519816
PMID: 25302300 [PubMed - as supplied by publisher]

Synaptojanin 1 Mutation in Parkinson's Disease Brings Further Insight into the Neuropathological Mechanisms.
Valérie Drouet, Suzanne Lesage
Biomed Res Int 2014 ; 2014:289728
PMID: 25302295 [PubMed - as supplied by publisher]

Evaluation of measures of upper limb functioning and disability in people with Parkinson's disease: a systematic review.
Elizabeth Proud, Kimberly J Miller, Belinda Bilney, Sulakshana Balachandran, Jennifer McGinley, Meg E Morris
Arch Phys Med Rehabil 2014 Oct;
PMID: 25301441 [PubMed - as supplied by publisher]

Diagnostics and therapy of "freezing of gait" in patients with Parkinson's disease].
M Amarell, F Cepuran, L Timmermann, N Allert, M T Barbe
Fortschr Neurol Psychiatr 2014 Oct; 82(10):593-605
PMID: 25299631 [PubMed - as supplied by publisher]

Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap?
Gurdeep Marwarha, Othman Ghribi
Exp Gerontol 2014 Sep;
PMID: 25261765 [PubMed - as supplied by publisher]

Pre-existing immunity to AAV2 limits transgene expression following intracerebral AAV2-based gene delivery in a 6-OHDA model of Parkinson's disease.
Shorena Janelidze, Ulrika Nordström, Sebastian Kügler, Patrik Brundin
J Gene Med 2014 Oct;
PMID: 25303717 [PubMed - as supplied by publisher]

Intranasal delivery of bone marrow derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer?s and Parkinson?s disease.
Lusine Danielyan, Sandra Beer-Hammer, Alexandra Stolzing, Richard Sch Fer, Georg Siegel, Claire Fabian, Philipp Kahle, Tilo Biedermann, Ali Lourhmati, Marine Buadze, Ana Novakovic, Barbara Proksch, Christoph H Gleiter, William H Frey Ii, Matthias Schwab
Cell Transplant 2014 Oct;
PMID: 25302802 [PubMed - as supplied by publisher]

Effects of dopaminergic treatment on functional cortico-cortical connectivity in Parkinson's disease.
S Zittel, C Heinbokel, J P M van der Vegt, E Niessen, C Buhmann, C Gerloff, H R Siebner, A Münchau, T Bäumer
Exp Brain Res 2014 Oct;
PMID: 25300961 [PubMed - as supplied by publisher]

Dopaminergic Neuron-Like Cells Derived from Bone Marrow Mesenchymal Stem Cells by Lmx1? and Neurturin Overexpression for Autologous Cytotherapy in Hemiparkinsonian Rhesus Monkeys.
Wan-Pu Wang, Zhan-Long He, Shuai-Yao Lu, Min Yan, Yan Zhou, Tian-Hong Xie, Na Yin, Wen-Ju Wang, Dong-Hong Tang, Hong-Jun Li, Mao-Sheng Sun
Curr Stem Cell Res Ther 2014 Oct;
PMID: 25300822 [PubMed - as supplied by publisher]

Classics in Chemical Neuroscience: Levodopa.
A Connor Whitfield, Ben T Moore, R Nathan Daniels
ACS Chem Neurosci 2014 Oct;
PMID: 25270271 [PubMed - as supplied by publisher]

Orofaryngeale slikstoornissen bij de ziekte van Parkinson.
J G Kalf
Tijdschr Gerontol Geriatr 2014 Oct; 45(5):282-9
PMID: 25246068 [PubMed - as supplied by publisher]

The Newly Discovered Parkinson's Disease Associated Finnish Mutation (A53E) Attenuates ?-Synuclein Aggregation and Membrane Binding.
Dhiman Ghosh, Shruti Sahay, Priyatosh Ranjan, Shimul Salot, Ganesh M Mohite, Pradeep K Singh, Saumya Dwivedi, Edmund Carvalho, Rinti Banerjee, Ashutosh Kumar, Samir K Maji
Biochemistry 2014 Oct;
PMID: 25268550 [PubMed - as supplied by publisher]

Neural cell adhesion molecules belonging to the family of leucine-rich repeat proteins.
Malene Winther, Peter S Walmod
Adv Neurobiol 2014 ; 8:315-95
PMID: 25300143 [PubMed - as supplied by publisher]

Identifying distinct candidate genes for early Parkinson's disease by analysis of gene expression in whole blood.
Ai-Guo Sun, Jing Wang, Yao-Zhong Shan, Wen-Jiao Yu, Xin Li, Chao-Hua Cong, Xin Wang
Neuro Endocrinol Lett 2014 Sep; 35(5):398-404
PMID: 25275262 [PubMed - as supplied by publisher]

Effects of levodopa on regional cerebral metabolism and blood flow.
Ji Hyun Ko, Renata P Lerner, David Eidelberg
Mov Disord 2014 Oct;
PMID: 25296957 [PubMed - as supplied by publisher]

Formation of ?-Synuclein Lewy Neurite-like aggregates in Axons Impedes the Transport of Distinct Endosomes.
Laura A Volpicelli-Daley, Karen L Gamble, Christine E Schultheiss, Dawn M Riddle, Andrew B West, Virginia M-Y Lee
Mol Biol Cell 2014 Oct;
PMID: 25298402 [PubMed - as supplied by publisher]

A novel compound VSC2 has anti-inflammatory and antioxidant properties in microglia and in Parkinson's disease animal model.
Ji Ae Lee, Ji Hyun Kim, Seo Yeon Woo, Hyo Jin Son, Se Hee Han, Bo Ko Jang, Ji Won Choi, Dong Jin Kim, Ki Duk Park, Onyou Hwang
Br J Pharmacol 2014 Oct;
PMID: 25297649 [PubMed - as supplied by publisher]

Mutant ?-Synuclein Enhances Firing Frequencies in Dopamine Substantia Nigra Neurons by Oxidative Impairment of A-Type Potassium Channels.
Mahalakshmi Subramaniam, Daniel Althof, Suzana Gispert, Jochen Schwenk, Georg Auburger, Akos Kulik, Bernd Fakler, Jochen Roeper
J Neurosci 2014 Oct; 34(41):13586-99
PMID: 25297088 [PubMed - as supplied by publisher]

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.
Staffan Holmqvist, Oldriska Chutna, Luc Bousset, Patrick Aldrin-Kirk, Wen Li, Tomas Björklund, Zhan-You Wang, Laurent Roybon, Ronald Melki, Jia-Yi Li
Acta Neuropathol 2014 Oct;
PMID: 25296989 [PubMed - as supplied by publisher]

Potentiation of neurotoxicity in double mutant mice with Pink1 ablation and A53T-SNCA overexpression.
Suzana Gispert, Nadine Brehm, Jonas Weil, Kay Seidel, Udo Rüb, Beatrice Kern, Michael Walter, Jochen Roeper, Georg Auburger
Hum Mol Genet 2014 Oct;
PMID: 25296918 [PubMed - as supplied by publisher]

Early oligomerization stages for the non-amyloid component of ?-synuclein amyloid.
Cindie Eugene, Rozita Laghaei, Normand Mousseau
J Chem Phys 2014 Oct; 141(13):135103
PMID: 25296841 [PubMed - as supplied by publisher]

Electrochemical techniques for subsecond neurotransmitter detection in live rodents.
Kevin N Hascup, Erin R Hascup
Comp Med 2014 ; 64(4):249-55
PMID: 25296011 [PubMed - as supplied by publisher]

LC-MS-Based Urinary Metabolite Signatures in Idiopathic Parkinson's Disease.
Hemi Luan, Liang-Feng Liu, Nan Meng, Zhi Tang, Ka-Kit Chua, Lei-Lei Chen, Ju-Xian Song, Vincent C T Mok, Li-Xia Xie, Min Li, Zongwei Cai
J Proteome Res 2014 Oct;
PMID: 25271123 [PubMed - as supplied by publisher]

Should genetic testing for SCAs be included in the diagnostic workup for MSA?
Han-Joon Kim, Beom S Jeon, Junghwan Shin, Woong-Woo Lee, Hyeyoung Park, Yu Jin Jung, Gwanhee Ehm
Neurology 2014 Oct;
PMID: 25298309 [PubMed - as supplied by publisher]

Aldehyde dehydrogenase (ALDH) in Alzheimer's and Parkinson's disease.
Edna Grünblatt, Peter Riederer
J Neural Transm 2014 Oct;
PMID: 25298080 [PubMed - as supplied by publisher]

Parkinsonism associated with multiple sclerosis: A report of eight new cases and a review on the literature.
Masoud Etemadifar, Farshid Afshar, Zahra Nasr, Mohsen Kheradmand
Iran J Neurol 2014 Apr; 13(2):88-93
PMID: 25295152 [PubMed - as supplied by publisher]

Risk of Parkinson's disease following severe constipation: A nationwide population-based cohort study.
Chin-Hsien Lin, Jou-Wei Lin, Ying-Chun Liu, Chia-Hsuin Chang, Ruey-Meei Wu
Parkinsonism Relat Disord 2014 Sep;
PMID: 25293395 [PubMed - as supplied by publisher]

Aptamers as Promising Molecular Recognition Elements for Diagnostics and Therapeutics in the Central Nervous System.
Erin M McConnell, Matthew R Holahan, Maria C DeRosa
Nucleic Acid Ther 2014 Oct;
PMID: 25296265 [PubMed - as supplied by publisher]

Toxicogenetics: in search of host susceptibility to environmental toxicants.
Gelareh Alam, Byron C Jones
Front Genet 2014 ; 5:327
PMID: 25295052 [PubMed - as supplied by publisher]

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
Yvette C Wong, Erika L F Holzbaur
Proc Natl Acad Sci U S A 2014 Oct;
PMID: 25294927 [PubMed - as supplied by publisher]

Targeting Hsp90/Hsp70-Based Protein Quality Control for Treatment of Adult Onset Neurodegenerative Diseases.
William B Pratt, Jason E Gestwicki, Yoichi Osawa, Andrew P Lieberman
Annu Rev Pharmacol Toxicol 2014 Sep;
PMID: 25292434 [PubMed - as supplied by publisher]

Ellagic Acid Mitigates SNO-PDI Induced Aggregation of Parkinsonian Biomarkers.
Parijat Kabiraj, Jose Eduardo Marin, Armando Varela-Ramirez, Emmanuel Zubia, Mahesh Narayan
ACS Chem Neurosci 2014 Oct;
PMID: 25247703 [PubMed - as supplied by publisher]

?-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation.
Jacqueline Burré, Manu Sharma, Thomas C Südhof
Proc Natl Acad Sci U S A 2014 Oct; 111(40):E4274-83
PMID: 25246573 [PubMed - as supplied by publisher]

An exome study of Parkinson's disease in Sardinia, a Mediterranean genetic isolate.
Marialuisa Quadri, Xu Yang, Giovanni Cossu, Simone Olgiati, Valeria M Saddi, Guido J Breedveld, Limei Ouyang, Jingchu Hu, Na Xu, Josja Graafland, Valeria Ricchi, Daniela Murgia, Leonor Correia Guedes, Claudio Mariani, Maria J Marti, Patrizia Tarantino, Rosanna Asselta, Francesc Valldeoriola, Monica Gagliardi, Gianni Pezzoli, Mario Ezquerra, Aldo Quattrone, Joaquim Ferreira, Grazia Annesi, Stefano Goldwurm, Eduardo Tolosa, Ben A Oostra, Maurizio Melis, Jun Wang, Vincenzo Bonifati
Neurogenetics 2014 Oct;
PMID: 25294124 [PubMed - as supplied by publisher]

The case for case reports.
Shamik Bhattacharrya, Julie Miller, Allan H Ropper
Ann Neurol 2014 Oct; 76(4):484-6
PMID: 25178674 [PubMed - as supplied by publisher]

Correlation Between 123I-FP-CIT Brain SPECT and Parkinsonism in Dementia With Lewy Bodies: Caveat for Clinical Use.
Angelo Del Sole, Giulia Perini, Michela Lecchi, Claudio Mariani, Giovanni Lucignani, Francesca Clerici
Clin Nucl Med 2014 Oct;
PMID: 25290294 [PubMed - as supplied by publisher]

The associations between fatigue, apathy, and depression in Parkinson's disease.
M Skorvanek, Z Gdovinova, J Rosenberger, R Ghorbani Saeedian, I Nagyova, J W Groothoff, J P van Dijk
Acta Neurol Scand 2014 Oct;
PMID: 25288130 [PubMed - as supplied by publisher]

An individual rehabilitation program: Evaluation by Parkinsonian patients and their physiotherapists.
F Ory Magne, N Fabre, C Gu, C Pastorelli, S Tardez, J-C Marchat, P Marque, C Brefel Courbon
Rev Neurol (Paris) 2014 Oct;
PMID: 25287732 [PubMed - as supplied by publisher]

A High Efficiency Induction of Dopaminergic Cells from Human Umbilical Mesenchymal Stem Cells for the Treatment of Hemiparkinsonian Rats.
Cell Transplant 2014 Oct;
PMID: 25289862 [PubMed - as supplied by publisher]

Twiddler (or Not) Syndrome: Questioning etiology for an uncommon form of hardware malfunction in deep brain stimulation.
Pedro Alberto Silva, Clara Chamadoira, Henrique Costa, Paulo Linhares, Maria José Rosas, Rui Vaz
Surg Neurol Int 2014 ; 5(Suppl 8):S410-2
PMID: 25289171 [PubMed - as supplied by publisher]

A manic episode after bilateral subthalamic stimulation in a patient with advanced Parkinson's disease.
Isabel Claeys, Patrick Santens, Dirk Van den Abbeele, Dirk Van Roost, Gilbert Md Lemmens
Acta Neuropsychiatr 2013 Dec; 25(6):367-9
PMID: 25287878 [PubMed - as supplied by publisher]

Directed dopaminergic neuron differentiation from human pluripotent stem cells.
Pengbo Zhang, Ninuo Xia, Renee A Reijo Pera
J Vis Exp 2014 ; (91)
PMID: 25285746 [PubMed - as supplied by publisher]

In vivo evidence of pathogenicity of VPS35 mutations in the Drosophila.
Hua-Shan Wang, Joanne Toh, Patrick Ho, Murni Tio, Yi Zhao, Eng-King Tan
Mol Brain 2014 Oct; 7(1):73
PMID: 25288323 [PubMed - as supplied by publisher]

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
, M C Cornelis, E M Byrne, T Esko, M A Nalls, A Ganna, N Paynter, K L Monda, N Amin, K Fischer, F Renstrom, J S Ngwa, V Huikari, A Cavadino, I M Nolte, A Teumer, K Yu, P Marques-Vidal, R Rawal, A Manichaikul, M K Wojczynski, J M Vink, J H Zhao, G Burlutsky, J Lahti, V Mikkilä, R N Lemaitre, J Eriksson, S K Musani, T Tanaka, F Geller, J Luan, J Hui, R Mägi, M Dimitriou, M E Garcia, W-K Ho, M J Wright, L M Rose, P K E Magnusson, N L Pedersen, D Couper, B A Oostra, A Hofman, M A Ikram, H W Tiemeier, A G Uitterlinden, F J A van Rooij, I Barroso, I Johansson, L Xue, M Kaakinen, L Milani, C Power, H Snieder, R P Stolk, S E Baumeister, R Biffar, F Gu, F Bastardot, Z Kutalik, D R Jacobs, N G Forouhi, E Mihailov, L Lind, C Lindgren, K Michaëlsson, A Morris, M Jensen, K-T Khaw, R N Luben, J J Wang, S Männistö, M-M Perälä, M Kähönen, T Lehtimäki, J Viikari, D Mozaffarian, K Mukamal, B M Psaty, A Döring, A C Heath, G W Montgomery, N Dahmen, T Carithers, K L Tucker, L Ferrucci, H A Boyd, M Melbye, J L Treur, D Mellström, J J Hottenga, I Prokopenko, A Tönjes, P Deloukas, S Kanoni, M Lorentzon, D K Houston, Y Liu, J Danesh, A Rasheed, M A Mason, A B Zonderman, L Franke, B S Kristal, , , , J Karjalainen, D R Reed, H-J Westra, M K Evans, D Saleheen, T B Harris, G Dedoussis, G Curhan, M Stumvoll, J Beilby, L R Pasquale, B Feenstra, S Bandinelli, J M Ordovas, A T Chan, U Peters, C Ohlsson, C Gieger, N G Martin, M Waldenberger, D S Siscovick, O Raitakari, J G Eriksson, P Mitchell, D J Hunter, P Kraft, E B Rimm, D I Boomsma, I B Borecki, R J F Loos, N J Wareham, P Vollenweider, N Caporaso, H J Grabe, M L Neuhouser, B H R Wolffenbuttel, F B Hu, E Hyppönen, M-R Järvelin, L A Cupples, P W Franks, P M Ridker, C M van Duijn, G Heiss, A Metspalu, K E North, E Ingelsson, J A Nettleton, R M van Dam, D I Chasman
Mol Psychiatry 2014 Oct;
PMID: 25288136 [PubMed - as supplied by publisher]

Involvement of the sodium-calcium exchanger 3 (NCX3) in ziram-induced calcium dysregulation and toxicity.
J Jin, A J Lao, M Katsura, A Caputo, F E Schweizer, S Sokolow
Neurotoxicology 2014 Oct;
PMID: 25284465 [PubMed - as supplied by publisher]

AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo.
Kim-Ann Saal, Jan C Koch, Lars Tatenhorst, Eva M Szeg?, Vinicius Toledo Ribas, Uwe Michel, Mathias Bähr, Lars Tönges, Paul Lingor
Neurobiol Dis 2014 Oct;
PMID: 25283984 [PubMed - as supplied by publisher]

Besides Fibrillization: Putative Role of the Peptide Fragment 71-82 on the Structural and Assembly Behavior of ?-Synuclein.
Laurie Bédard, Thierry Lefčvre, Emilie Morin-Michaud, Michčle Auger
Biochemistry 2014 Oct;
PMID: 25255476 [PubMed - as supplied by publisher]

Novel alleles of the Drosophila LRRK2 homolog reveal a crucial role in endolysosomal functions and autophagy in vivo.
Mark W Dodson, Lok K Leung, Mohiddin Lone, Michael A Lizzio, Ming Guo
Dis Model Mech 2014 Oct;
PMID: 25288684 [PubMed - as supplied by publisher]

Acoustic and perceptual correlates of faster-than-habitual speech produced by speakers with Parkinson's disease and multiple sclerosis.
Christina Kuo, Kris Tjaden, Joan E Sussman
J Commun Disord 2014 Oct;
PMID: 25287378 [PubMed - as supplied by publisher]

Parkinsonian gait ameliorated with a moving handrail, not with a banister.
Ely Rabin, Aleksandr Demin, Stefania Pirrotta, Jason Chen, Hemal Patel, Ankur Bhambri, Estella Noyola, James R Lackner, Paul DiZio, Joanne DiFrancisco-Donoghue, William Werner
Arch Phys Med Rehabil 2014 Oct;
PMID: 25286436 [PubMed - as supplied by publisher]

Restless Genital Syndrome in Parkinson Disease.
Camila C Aquino, Tiago Mestre, Anthony E Lang
JAMA Neurol 2014 Oct;
PMID: 25285600 [PubMed - as supplied by publisher]

Interaction of Noradrenergic Pharmacological Manipulation and Subthalamic Stimulation on Movement Initiation Control in Parkinson's Disease.
Marion Albares, Stéphane Thobois, Emilie Favre, Emmanuel Broussolle, Gustavo Polo, Philippe Domenech, Philippe Boulinguez, Bénédicte Ballanger
Brain Stimul 2014 Sep;
PMID: 25284704 [PubMed - as supplied by publisher]

Tetsuhito Fukushima, Xiaodong Tan, Yunwen Luo, Puqing Wang, Jinhui Song, Hideyuki Kanda, Takehito Hayakawa, Tomohiro Kumagai, Takeyasu Kakamu, Masayoshi Tsuji, Tomoo Hidaka, Yayoi Mori
Fukushima J Med Sci 2014 Oct;
PMID: 25283978 [PubMed - as supplied by publisher]

Effects of augmented visual feedback during balance training in Parkinson's disease: A pilot randomized clinical trial.
Maarten R C van den Heuvel, Gert Kwakkel, Peter J Beek, Henk W Berendse, Andreas Daffertshofer, Erwin E H van Wegen
Parkinsonism Relat Disord 2014 Sep;
PMID: 25283070 [PubMed - as supplied by publisher]

Quantitative and qualitative gait assessments in Parkinson's disease patients.
Milica D Djuri?-Jovici?, Nenad S Jovici?, Sasa M Radovanovi?, Nikola D Kresojevi?, Vladimir S Kosti?, Mirjana B Popovi?
Vojnosanit Pregl 2014 Sep; 71(9):809-16
PMID: 25282777 [PubMed - as supplied by publisher]

Dance as an intervention for people with Parkinson's disease: A systematic review and meta-analysis.
Kathryn Sharp, Jonathan Hewitt
Neurosci Biobehav Rev 2014 Sep;
PMID: 25268548 [PubMed - as supplied by publisher]

Endometrial stem cell transplantation in MPTP- exposed primates: an alternative cell source for treatment of Parkinson's disease.
Erin F Wolff, Levent Mutlu, Efi E Massasa, John D Elsworth, D Eugene Redmond, Hugh S Taylor
J Cell Mol Med 2014 Oct;
PMID: 25283241 [PubMed - as supplied by publisher]

Alpha synuclein is transported into and out of the brain by the blood-brain barrier.
Yu-Ting Sui, Kristin M Bullock, Michelle A Erickson, Jing Zhang, W A Banks
Peptides 2014 Sep;
PMID: 25278492 [PubMed - as supplied by publisher]

Primary familial brain calcification: Genetic analysis and clinical spectrum.
Ilaria Taglia, Andrea Mignarri, Simone Olgiati, Elisabetta Menci, Patrizia L Petrocelli, Guido J Breedveld, Cesa Scaglione, Paolo Martinelli, Antonio Federico, Vincenzo Bonifati, Maria Teresa Dotti
Mov Disord 2014 Oct;
PMID: 25284758 [PubMed - as supplied by publisher]

MiRNA Profile in the Substantia Nigra of Parkinson's Disease and Healthy Subjects.
Lucía F Cardo, Eliecer Coto, René Ribacoba, Manuel Menéndez, Germán Moris, Esther Suárez, Victoria Alvarez
J Mol Neurosci 2014 Oct;
PMID: 25284245 [PubMed - as supplied by publisher]

The Melanocortin 1 Receptor (Mc1r) Variants Do Not Account for the Co-occurrence of Parkinson's Disease and Malignant Melanoma.
Sandra Elincx-Benizri, Rivka Inzelberg, Lior Greenbaum, Oren S Cohen, Gilad Yahalom, Yael Laitman, Ruth Djaldetti, Yael Orlev, Alon Scope, Esther Azizi, Eitan Friedman, Sharon Hassin-Baer
J Mol Neurosci 2014 Oct;
PMID: 25284244 [PubMed - as supplied by publisher]

Anticholinergic Drug Use and Negative Outcomes Among the Frail Elderly Population Living in a Nursing Home.
Francesco Landi, Giuseppina Dell'Aquila, Agnese Collamati, Anna Maria Martone, Giovanni Zuliani, Beatrice Gasperini, Paolo Eusebi, Fabrizia Lattanzio, Antonio Cherubini
J Am Med Dir Assoc 2014 Oct;
PMID: 25282629 [PubMed - as supplied by publisher]

Efficacy and Safety of High-Dose Propranolol for the Management of Infant Supraventricular Tachyarrhythmias.
Andrea L Barton, Brady S Moffett, Santiago O Valdes, Christina Miyake, Jeffrey J Kim
J Pediatr 2014 Oct;
PMID: 25282062 [PubMed - as supplied by publisher]

Sensory contribution to vocal emotion deficit in Parkinson's disease after subthalamic stimulation.
Julie Péron, Sezen Cekic, Claire Haegelen, Paul Sauleau, Sona Patel, Dominique Drapier, Marc Vérin, Didier Grandjean
Cortex 2014 Sep; 63C:172-183
PMID: 25282055 [PubMed - as supplied by publisher]

Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson's disease.
Eva M Müller-Oehring, Edith V Sullivan, Adolf Pfefferbaum, Neng C Huang, Kathleen L Poston, Helen M Bronte-Stewart, Tilman Schulte
Brain Imaging Behav 2014 Oct;
PMID: 25280970 [PubMed - as supplied by publisher]

Parkinson's disease beyond 20?years.
Roberto Cilia, Emanuele Cereda, Catherine Klersy, Margherita Canesi, Anna L Zecchinelli, Claudio B Mariani, Silvana Tesei, Giorgio Sacilotto, Nicoletta Meucci, Michela Zini, Claudio Ruffmann, Ioannis U Isaias, Stefano Goldwurm, Gianni Pezzoli
J Neurol Neurosurg Psychiatry 2014 Oct;
PMID: 25280915 [PubMed - as supplied by publisher]

Distinct phenotypes of speech and voice disorders in Parkinson's disease after subthalamic nucleus deep brain stimulation.
Takashi Tsuboi, Hirohisa Watanabe, Yasuhiro Tanaka, Reiko Ohdake, Noritaka Yoneyama, Kazuhiro Hara, Ryoichi Nakamura, Hazuki Watanabe, Jo Senda, Naoki Atsuta, Mizuki Ito, Masaaki Hirayama, Masahiko Yamamoto, Yasushi Fujimoto, Yasukazu Kajita, Toshihiko Wakabayashi, Gen Sobue
J Neurol Neurosurg Psychiatry 2014 Oct;
PMID: 25280914 [PubMed - as supplied by publisher]

The dopaminergic system in upper limb motor blocks (ULMB) investigated during bimanual coordination in Parkinson's disease (PD).
Matt J N Brown, Quincy J Almeida, Fariborz Rahimi
J Neurol 2014 Oct;
PMID: 25280861 [PubMed - as supplied by publisher]

Protective effect of hesperidin in a model of Parkinson's disease induced by 6-hydroxydopamine in aged mice.
Michelle S Antunes, André T R Goes, Silvana P Boeira, Marina Prigol, Cristiano R Jesse
Nutrition 2014 Nov-Dec; 30(11-12):1415-22
PMID: 25280422 [PubMed - as supplied by publisher]

Reduced topological efficiency in cortical-Basal Ganglia motor network of Parkinson's disease: a resting state FMRI study.
Luqing Wei, Jiuquan Zhang, Zhiliang Long, Guo-Rong Wu, Xiaofei Hu, Yanling Zhang, Jian Wang
PLoS One 2014 ; 9(10):e108124
PMID: 25279557 [PubMed - as supplied by publisher]

Microencapsulation of dopamine neurons derived from human induced pluripotent stem cells.
Shuhei Konagaya, Hiroo Iwata
Biochim Biophys Acta 2014 Oct;
PMID: 25281770 [PubMed - as supplied by publisher]

Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism.
Ching-Chi Chiu, Tu-Hsueh Yeh, Szu-Chia Lai, Yah-Huei Wu-Chou, Che-Hong Chen, Daria Mochly-Rosen, Yin-Cheng Huang, Yu-Jie Chen, Chao-Lang Chen, Ya-Ming Chang, Hung-Li Wang, Chin-Song Lu
Exp Neurol 2014 Sep;
PMID: 25263579 [PubMed - as supplied by publisher]

The ?7 nicotinic receptor agonist ABT-107 protects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions.
Tanuja Bordia, Matthew McGregor, Roger L Papke, Michael W Decker, J Michael McIntosh, Maryka Quik
Exp Neurol 2014 Sep;
PMID: 25261754 [PubMed - as supplied by publisher]

Parkinson's disease and age: The obvious but largely unexplored link.
Rashed Abdullah, Indranil Basak, Ketan S Patil, Guido Alves, Jan Petter Larsen, Simon Geir Mřller
Exp Gerontol 2014 Sep;
PMID: 25261764 [PubMed - as supplied by publisher]

An overview of the molecular mechanisms and novel roles of Nrf2 in neurodegenerative disorders.
Yang Yang, Shuai Jiang, Juanjuan Yan, Yue Li, Zhenlong Xin, Yan Lin, Yan Qu
Cytokine Growth Factor Rev 2014 Sep;
PMID: 25280871 [PubMed - as supplied by publisher]

Network Analysis Identifies SOD2 mRNA as a Potential Biomarker for Parkinson's Disease.
Jose A Santiago, Clemens R Scherzer, Judith A Potashkin
PLoS One 2014 ; 9(10):e109042
PMID: 25279756 [PubMed - as supplied by publisher]

The effects of brain stimulation of subthalamic nucleus surgery on gait and balance performance in Parkinson disease. A pilot study.
Filiz Altu?, Feridun Acar, Göksemin Acar, U?ur Cavlak
Arch Med Sci 2014 Aug; 10(4):733-8
PMID: 25276158 [PubMed - as supplied by publisher]

Influence of functional movement rehabilitation on quality of life in people with Parkinson's disease.
Joanna Cholewa, Agnieszka Gorzkowska, Michal Szepelawy, Agnieszka Nawrocka, Jaroslaw Cholewa
J Phys Ther Sci 2014 Sep; 26(9):1329-31
PMID: 25276010 [PubMed - as supplied by publisher]

Continuous infusion of levodopa-carbidopa intestinal gel in Parkinson's disease.
Lalitha N Guthikonda, Kelly E Lyons, Rajesh Pahwa
J Comp Eff Res 2014 Jul; 3(4):331-3
PMID: 25275230 [PubMed - as supplied by publisher]

Human Umbilical Cord Mesenchymal Stem Cells Infected with Adenovirus Expressing HGF Promote Regeneration of Damaged Neuron Cells in a Parkinson's Disease Model.
Xin-Shan Liu, Jin-Feng Li, Shan-Shan Wang, Yu-Tong Wang, Yu-Zhen Zhang, Hong-Lei Yin, Shuang Geng, Hui-Cui Gong, Bing Han, Yun-Liang Wang
Biomed Res Int 2014 ; 2014:909657
PMID: 25276829 [PubMed - as supplied by publisher]

E2F1 in neurons is cleaved by calpain in an NMDA receptor-dependent manner in a model of HIV-induced neurotoxicity.
Jacob W Zyskind, Ying Wang, Giyong Cho, Jenhao H Ting, Dennis L Kolson, David R Lynch, Kelly L Jordan-Sciutto
J Neurochem 2014 Oct;
PMID: 25279448 [PubMed - as supplied by publisher]

Meta-analyses of seven GIGYF2 polymorphisms with Parkinson's disease.
Dongjun Dai, Yunliang Wang, Xingyu Zhou, Jianmin Tao, Danjie Jiang, Hanlin Zhou, Yi Jiang, Guanghui Pan, Ping Ru, Huihui Ji, Jinfeng Li, Yuzheng Zhang, Honglei Yin, Mingqing Xu, Shiwei Duan
Biomed Rep 2014 Nov; 2(6):886-892
PMID: 25279164 [PubMed - as supplied by publisher]

Mendelian randomization of serum urate and parkinson disease progression.
Kelly Claire Simon, Shirley Eberly, Xiang Gao, David Oakes, Caroline M Tanner, Ira Shoulson, Stanley Fahn, Michael A Schwarzschild, Alberto Ascherio,
Ann Neurol 2014 Sep;
PMID: 25257975 [PubMed - as supplied by publisher]

Erratum to: Do CSF levels of t-Tau, p-Tau and ?1-42 amyloid correlate with dopaminergic system impairment in patients with a clinical diagnosis of Parkinson disease? A (123)I-FP-CIT study in the early stages of the disease.
Agostino Chiaravalloti, Alessandro Stefani, Alessandro Fiorentini, Annamaria Lacanfora, Paolo Stanzione, Orazio Schillaci
Eur J Nucl Med Mol Imaging 2014 Nov; 41(11):2165-6
PMID: 25236909 [PubMed - as supplied by publisher]

Oxidative stress, redox signalling and endothelial dysfunction in ageing-related neurodegenerative diseases: a role of NADPH oxidase 2.
Sarah Cahill-Smith, Jian-Mei Li
Br J Clin Pharmacol 2014 Sep; 78(3):441-53
PMID: 25279404 [PubMed - as supplied by publisher]

Predicting quality of life outcomes after subthalamic nucleus deep brain stimulation.
Darlene Floden, Scott E Cooper, Sandra D Griffith, Andre G Machado
Neurology 2014 Oct;
PMID: 25274851 [PubMed - as supplied by publisher]

Central pharmacokinetics of levodopa: Lessons from imaging studies.
A Jon Stoessl
Mov Disord 2014 Oct;
PMID: 25274160 [PubMed - as supplied by publisher]

Serotonergic antidepressant drugs and L-dopa-induced dyskinesias in Parkinson's disease.
S Mazzucchi, D Frosini, A Ripoli, V Nicoletti, G Linsalata, U Bonuccelli, R Ceravolo
Acta Neurol Scand 2014 Oct;
PMID: 25274076 [PubMed - as supplied by publisher]

Education-corrected CERAD identifies MCI and dementia in Parkinson's disease.
M Karrasch, S Laatu, U Ellfolk, R Marttila, K Martikainen
Acta Neurol Scand 2014 Oct;
PMID: 25273524 [PubMed - as supplied by publisher]

Investigation of muscle tone in patients with Parkinson's disease in unloading conditions].
I A Solopova, V A Selionov, Iu P Zhvanski?, L A Ivanenko, L A Chernikov
Fiziol Cheloveka 2014 Mar-Apr; 40(2):14-21
PMID: 25272702 [PubMed - as supplied by publisher]

Dental Stem Cell in Tooth Development and Advances of Adult Dental Stem Cell in Regenerative Therapies.
Jiali Tan, Xin Xu, Jiong Lin, Li Fan, Yuting Zheng, Wei Kuang
Curr Stem Cell Res Ther 2014 Oct;
PMID: 25274563 [PubMed - as supplied by publisher]

Control effects of stimulus paradigms on characteristic firings of parkinsonism.
Honghui Zhang, Qingyun Wang, Guanrong Chen
Chaos 2014 Sep; 24(3):033134
PMID: 25273214 [PubMed - as supplied by publisher]

Maneb-induced dopaminergic neuronal death is not affected by loss of mitochondrial complex I activity: results from primary mesencephalic dopaminergic neurons cultured from individual Ndufs4+/+ and Ndufs4-/- mouse embryos.
Won-Seok Choi, Zhengui Xia
Neuroreport 2014 Oct;
PMID: 25275677 [PubMed - as supplied by publisher]

Methylglyoxal increased dopamine level and led to oxidative stress in SH-SY5Y cells.
Bingjie Xie, Fankai Lin, Lei Peng, Kaleem Ullah, Hanyan Wu, Hong Qing, Yulin Deng
Acta Biochim Biophys Sin (Shanghai) 2014 Oct;
PMID: 25274329 [PubMed - as supplied by publisher]

Acute increase of ?-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation.
David J Busch, Paul A Oliphint, Rylie B Walsh, Susan M L Banks, Wendy S Woods, Julia M George, Jennifer R Morgan
Mol Biol Cell 2014 Oct;
PMID: 25273557 [PubMed - as supplied by publisher]

Mechanism of the beneficial effect of melatonin in experimental Parkinson's disease.
Fatos Belgin Yildirim, Ozlem Ozsoy, Gamze Tanriover, Yasemin Kaya, Eren Ogut, Burcu Gemici, Sayra Dilmac, Ayse Ozkan, Aysel Agar, Mutay Aslan
Neurochem Int 2014 Sep;
PMID: 25263280 [PubMed - as supplied by publisher]

Cholesterol in brain disease: sometimes determinant and frequently implicated.
Mauricio G Martín, Frank Pfrieger, Carlos G Dotti
EMBO Rep 2014 Oct; 15(10):1036-1052
PMID: 25223281 [PubMed - as supplied by publisher]

A Survey of Parkinson's Disease Patients: Most Bothersome Symptoms and Coping Preferences.
Lisa A Uebelacker, Gary Epstein-Lubow, Trevor Lewis, Monica K Broughton, Joseph H Friedman
J Parkinsons Dis 2014 Sep;
PMID: 25271239 [PubMed - as supplied by publisher]

Risk Factors for Frequent Falls In People with Parkinson's Disease.
Serene S Paul, Natalie E Allen, Cathie Sherrington, Gillian Heller, Victor S C Fung, Jacqueline C T Close, Stephen R Lord, Colleen G Canning
J Parkinsons Dis 2014 Sep;
PMID: 25271238 [PubMed - as supplied by publisher]

Clinical workout for the early detection of cognitive decline and dementia.
M Tsolaki
Eur J Clin Nutr 2014 Oct;
PMID: 25271010 [PubMed - as supplied by publisher]

Real life cost and quality of life associated with continuous intraduodenal levodopa infusion compared with oral treatment in Parkinson patients.
Christofer Lundqvist, Antonie Gićver Beiske, Ola Reiertsen, Ivar Sřnbř Kristiansen
J Neurol 2014 Oct;
PMID: 25270681 [PubMed - as supplied by publisher]

Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's disease: An international multicenter study.
A Rizos, P Martinez-Martin, P Odin, A Antonini, B Kessel, T Klemencic Kozul, A Todorova, A Douiri, A Martin, F Stocchi, E Dietrichs, K Ray Chaudhuri,
Parkinsonism Relat Disord 2014 Sep;
PMID: 25269446 [PubMed - as supplied by publisher]

Cypermethrin alters the status of oxidative stress in the peripheral blood: relevance to Parkinsonism.
Pratibha Tripathi, Ashish Singh, Sonal Agrawal, Om Prakash, Mahendra Pratap Singh
J Physiol Biochem 2014 Oct;
PMID: 25270427 [PubMed - as supplied by publisher]

Chronic Amitriptyline Treatment Attenuates Nigrostriatal Degeneration and Significantly Alters Trophic Support in a Rat Model of Parkinsonism.
Katrina L Paumier, Caryl E Sortwell, Lalitha Madhavan, Brian Terpstra, Stephanie L Celano, Joshua J Green, Nastassja M Imus, Nathan Marckini, Brian Daley, Kathy Steece-Collier, Timothy J Collier
Neuropsychopharmacology 2014 Sep;
PMID: 25267343 [PubMed - as supplied by publisher]

Compound heterozygous PNPLA6 mutations cause Boucher-Neuhäuser syndrome with late-onset ataxia.
A Deik, B Johannes, J C Rucker, E Sánchez, S E Brodie, E Deegan, K Landy, Y Kajiwara, S Scelsa, R Saunders-Pullman, C Paisán-Ruiz
J Neurol 2014 Sep;
PMID: 25267340 [PubMed - as supplied by publisher]

Major depressive disorder in Parkinsonżs disease: a cross-sectional study from Sri Lanka.
Tharini Ketharanathan, Raveen Hanwella, Rajiv Weerasundera, Varuni A de Silva
BMC Psychiatry 2014 Sep; 14(1):278
PMID: 25266218 [PubMed - as supplied by publisher]

Gait in Huntingtonżs disease and the stride length-cadence relationship.
Mary Danoudis, Robert Iansek
BMC Neurol 2014 Oct; 14(1):161
PMID: 25265896 [PubMed - as supplied by publisher]

Apathy and dementia. Nosology, assessment and management.
Gabriele Cipriani, Claudio Lucetti, Sabrina Danti, Angelo Nuti
J Nerv Ment Dis 2014 Oct; 202(10):718-24
PMID: 25265266 [PubMed - as supplied by publisher]

Evidence-based design and development of a VR-based treadmill system for gait research and rehabilitation of patients with Parkinson's disease.
Alberto Isaac Pérez-Sanpablo, Arturo González-Mendoza, Ivett Quińones-Uriostegui, Gerardo Rodríguez-Reyes, Lidia Núńez-Carrera, Claudia Hernández-Arenas, Marie Catherine Boll-Woehrlen, Aldo Alessi Montero
Rev Invest Clin 2014 Jul; 66 Suppl 1:S39-47
PMID: 25264796 [PubMed - as supplied by publisher]

Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons.
A Ledonne, A Nobili, E C Latagliata, V Cavallucci, E Guatteo, S Puglisi-Allegra, M D'Amelio, N B Mercuri
Mol Psychiatry 2014 Sep;
PMID: 25266126 [PubMed - as supplied by publisher]

Neurotoxin-Induced Pathway Perturbation in Human Neuroblastoma SH-EP Cells.
Jin Hwan Do
Mol Cells 2014 Sep; 37(9):672-84
PMID: 25234470 [PubMed - as supplied by publisher]

Familiarization to treadmill walking in unimpaired Parkinson's disease patients.
Alberto Isaac Pérez-Sanpablo, Claudia Hernández-Arenas, Gerardo Rodríguez-Reyes, Ivett Quińones-Uriostegui, Aldo Alessi Montero, Lidia Núńez-Carrera, Marie Catherine Boll-Woehrlen, Carlos Galván Duque-Gastélum
Rev Invest Clin 2014 Jul; 66(Supl. 1):S24-S31
PMID: 25264794 [PubMed - as supplied by publisher]

Calculating clinical progression rates in Parkinson's disease: Methods matter.
Johan Marinus, Jorine F van der Heeden, Jacobus J van Hilten
Parkinsonism Relat Disord 2014 Aug;
PMID: 25264021 [PubMed - as supplied by publisher]

Electrophysiological registration of phonological perception in the subthalamic nucleus of patients with Parkinson's Disease.
M De Letter, A Aerts, J Van Borsel, S Vanhoutte, L De Taeye, R Raedt, P van Mierlo, P Boon, D Van Roost, P Santens
Brain Lang 2014 Sep; 138C:19-26
PMID: 25265552 [PubMed - as supplied by publisher]

Decision support framework for Parkinson's disease based on novel handwriting markers.
Peter Drotar, Jiri Mekyska, Irena Rektorova, Lucia Masarova, Zdenek Smekal, Marcos Zanuy
IEEE Trans Neural Syst Rehabil Eng 2014 Sep;
PMID: 25265632 [PubMed - as supplied by publisher]

The impact of STN deep brain stimulation on speech in individuals with Parkinson's disease: The patient's perspective.
Jeffrey Wertheimer, Ann Y Gottuso, Miriam Nuno, Carol Walton, Aurore Duboille, Margaret Tuchman, Lorraine Ramig
Parkinsonism Relat Disord 2014 Oct; 20(10):1065-70
PMID: 25048615 [PubMed - as supplied by publisher]

Natural history of falls in a population-based cohort of patients with Parkinson's disease: An 8-year prospective study.
Ylva Hivand Hiorth, Jan Petter Larsen, Kirsten Lode, Kenn Freddy Pedersen
Parkinsonism Relat Disord 2014 Oct; 20(10):1059-64
PMID: 25048614 [PubMed - as supplied by publisher]

Levodopa-carbidopa intestinal gel (LCIG) infusion during pregnancy and delivery: First documented case.
Yair Zlotnik, Nir Giladi, Ariela Hilel, Yami Shapira, Sarah Goldstein, Tanya Gurevich
Parkinsonism Relat Disord 2014 Sep;
PMID: 25262534 [PubMed - as supplied by publisher]

Sporadic inclusion-body myositis: A degenerative muscle disease associated with aging, impaired muscle protein homeostasis and abnormal mitophagy.
Valerie Askanas, W King Engel, Anna Nogalska
Biochim Biophys Acta 2014 Sep;
PMID: 25241263 [PubMed - as supplied by publisher]

Comparing the Fullerton Advanced Balance scale with the Mini-BESTest and Berg Balance Scale to assess postural control in patients with Parkinson's Disease.
Christian Schlenstedt, Stephanie Brombacher, Gesa Hartwigsen, Burkhard Weisser, Bettina Möller, Günther Deuschl
Arch Phys Med Rehabil 2014 Sep;
PMID: 25261718 [PubMed - as supplied by publisher]

Walking Economy During Cued Versus Non-Cued Self-Selected Treadmill Walking in Persons with Parkinson's Disease.
Paul M Gallo, Tara L McIsaac, Carol Ewing Garber
J Parkinsons Dis 2014 Sep;
PMID: 25261459 [PubMed - as supplied by publisher]

Applause sign in advanced Parkinson's disease.
N J Weerkamp, G Tissingh, P J E Poels, S U Zuidema, M Munneke, R T C M Koopmans, B R Bloem
Parkinsonism Relat Disord 2014 Aug;
PMID: 25260968 [PubMed - as supplied by publisher]

Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL.
Xiao-Yun Liu, Maria E Gonzalez-Toledo, Austin Fagan, Yanying Liu, Wei-Ming Duan, Siyuan Zhang, Bin Li, Chun-Shu Piao, Li-Ru Zhao
Neurobiol Dis 2014 Sep;
PMID: 25251607 [PubMed - as supplied by publisher]

Fetal stem cell transplantation: Past, present, and future.
Tetsuya Ishii, Koji Eto
World J Stem Cells 2014 Sep; 6(4):404-20
PMID: 25258662 [PubMed - as supplied by publisher]

Occurrence of Takotsubo syndrome in a patient with Parkinson's disease after entacapone add-on.
F Baldacci, A Vergallo, P Del Dotto, M Ulivi, C Palombo, G Casolo, G Tomei, U Bonuccelli
Parkinsonism Relat Disord 2014 Sep;
PMID: 25258328 [PubMed - as supplied by publisher]

Editorial: understanding the role of heteroreceptor complexes in the central nervous system.
Kjell Fuxe, Dasiel Borroto-Escuela, Gilberto Fisone, Luigi F Agnati, Sergio Tanganelli
Curr Protein Pept Sci 2014 ; 15(7):647
PMID: 25256022 [PubMed - as supplied by publisher]

Dopamine signaling leads to loss of polycomb repression and aberrant gene activation in experimental parkinsonism.
Erik Södersten, Michael Feyder, Mads Lerdrup, Ana-Luisa Gomes, Hanna Kryh, Giada Spigolon, Jocelyne Caboche, Gilberto Fisone, Klaus Hansen
PLoS Genet 2014 Sep; 10(9):e1004574
PMID: 25254549 [PubMed - as supplied by publisher]

Proposed Motor Scoring System in a Porcine Model of Parkinson's Disease induced by Chronic Subcutaneous Injection of MPTP.
Joon Ho Moon, Ji Ho Kim, Hyung-Jun Im, Dong Soo Lee, Eun Jung Park, Kilyoung Song, Hyun Ju Oh, Su Bin Hyun, Sang Chul Kang, Hyunil Kim, Hyo Eun Moon, Hyung Woo Park, Hong Jae Lee, Eun Ji Kim, Seokjoong Kim, Byeong Chun Lee, Sun Ha Paek
Exp Neurobiol 2014 Sep; 23(3):258-65
PMID: 25258574 [PubMed - as supplied by publisher]

Reduced alpha-synuclein in cerebrospinal fluid in synucleinopathies: Evidence from a meta-analysis.
Wataru Sako, Nagahisa Murakami, Yuishin Izumi, Ryuji Kaji
Mov Disord 2014 Sep;
PMID: 25258345 [PubMed - as supplied by publisher]

Interactions between Calcium and Alpha-Synuclein in Neurodegeneration.
Alex Rcom-H'cheo-Gauthier, Jacob Goodwin, Dean L Pountney
Biomolecules 2014 ; 4(3):795-811
PMID: 25256602 [PubMed - as supplied by publisher]

Air pollution and your brain: what do you need to know right now.
Lilian Calderón-Garcidueńas, Ana Calderón-Garcidueńas, Ricardo Torres-Jardón, José Avila-Ramírez, Randy J Kulesza, Amedeo D Angiulli
Prim Health Care Res Dev 2014 Sep; :1-17
PMID: 25256239 [PubMed - as supplied by publisher]

Visual signs and symptoms of multiple system atrophy.
Richard A Armstrong
Clin Exp Optom 2014 Sep;
PMID: 25256122 [PubMed - as supplied by publisher]

An activated sympathetic nervous system affects white adipocyte differentiation and lipolysis in a rat model of Parkinson's disease.
XiangZhi Meng, RuiPan Zheng, Ying Zhang, MingLiang Qiao, Li Liu, Peng Jing, LuLu Wang, Jing Liu, Yan Gao
J Neurosci Res 2014 Sep;
PMID: 25257318 [PubMed - as supplied by publisher]

Laterality and deep brain stimulation of the subthalamic nucleus: applying a dichotic listening task to patients treated for Parkinson's disease.
Rickard L Sjöberg, Björn Häggström, Johanna Philipsson, Jan Linder, Marwan Hariz, Patric Blomstedt
Neurocase 2014 Sep; :1-6
PMID: 25254607 [PubMed - as supplied by publisher]

Stimulation of ? Opioid Receptor and Blockade of Nociceptin/Orphanin FQ Receptor Synergistically Attenuate Parkinsonism.
Omar S Mabrouk, Riccardo Viaro, Mattia Volta, Ada Ledonne, Nicola Mercuri, Michele Morari
J Neurosci 2014 Sep; 34(39):12953-62
PMID: 25253844 [PubMed - as supplied by publisher]

Preoperative factors of apathy in subthalamic stimulated Parkinson disease: A PET study.
Gabriel H Robert, Florence Le Jeune, Clement Lozachmeur, Sophie Drapier, Thibaut Dondaine, Julie Péron, Jean-Francois Houvenaghel, David Travers, Paul Sauleau, Bruno Millet, Marc Vérin, Dominique Drapier
Neurology 2014 Sep;
PMID: 25253750 [PubMed - as supplied by publisher]

Neuroprotective effect of Buddleja cordata methanolic extract in the 1-methyl-4-phenylpyridinium Parkinson's disease rat model.
Gabriela Pérez-Barrón, José Guillermo Avila-Acevedo, Ana María García-Bores, Sergio Montes, Sara García-Jiménez, Ismael León-Rivera, Moisés Rubio-Osornio, Antonio Monroy-Noyola
J Nat Med 2014 Sep;
PMID: 25253176 [PubMed - as supplied by publisher]

ß-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network.
Bérangčre Deleglise, Sebastien Magnifico, Eric Duplus, Pauline Vaur, Vanessa Soubeyre, Morgane Belle, Maeva Vignes, Jean-Louis Viovy, Etienne Jacotot, Jean-Michel Peyrin, Bernard Brugg
Acta Neuropathol Commun 2014 Sep; 2(1):145
PMID: 25253021 [PubMed - as supplied by publisher]

Does anxiety cause freezing of gait in Parkinson's disease?
Kaylena A Ehgoetz Martens, Colin G Ellard, Quincy J Almeida
PLoS One 2014 ; 9(9):e106561
PMID: 25250691 [PubMed - as supplied by publisher]

LRRK2 Pathobiology in Parkinson's Disease.
Ian Martin, Jungwoo Wren Kim, Valina L Dawson, Ted M Dawson
J Neurochem 2014 Sep;
PMID: 25251388 [PubMed - as supplied by publisher]

Task specific inter-hemispheric coupling in human subthalamic nuclei.
Felix Darvas, Adam O Hebb
Front Hum Neurosci 2014 ; 8:701
PMID: 25249965 [PubMed - as supplied by publisher]

Electrophysiological evidence for functionally distinct neuronal populations in the human substantia nigra.
Ashwin G Ramayya, Kareem A Zaghloul, Christoph T Weidemann, Gordon H Baltuch, Michael J Kahana
Front Hum Neurosci 2014 ; 8:655
PMID: 25249957 [PubMed - as supplied by publisher]

Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.
Andrii Domanskyi, Heike Alter, Miriam A Vogt, Peter Gass, Ilya A Vinnikov
Front Cell Neurosci 2014 ; 8:275
PMID: 25249938 [PubMed - as supplied by publisher]

Evidence That Formulations of the Selective MAO-B Inhibitor, Selegiline, Which Bypass First-Pass Metabolism, Also Inhibit MAO-A in the Human Brain.
Joanna S Fowler, Jean Logan, Nora D Volkow, Elena Shumay, Fred McCall-Perez, Millard Jayne, Gene-Jack Wang, David L Alexoff, Karen Apelskog-Torres, Barbara Hubbard, Pauline Carter, Payton King, Stanley Fahn, Frank Telang, Colleen Shea, Youwen Xu, Lisa Muench
Neuropsychopharmacology 2014 Sep;
PMID: 25249059 [PubMed - as supplied by publisher]

Hyperprolactinemia and prolactinoma.
Johannes A Romijn
Handb Clin Neurol 2014 ; 124:185-95
PMID: 25248588 [PubMed - as supplied by publisher]

Alpha-synuclein as a Pathological Link between Chronic Traumatic Brain Injury and Parkinson's disease.
Sandra A Acosta, Naoki Tajiri, Ike de la Pena, Marina Bastawrous, Paul R Sanberg, Yuji Kaneko, Cesar V Borlongan
J Cell Physiol 2014 Sep;
PMID: 25251017 [PubMed - as supplied by publisher]

Glucocerebrosidase mutations in primary parkinsonism.
Rosanna Asselta, Valeria Rimoldi, Chiara Siri, Roberto Cilia, Ilaria Guella, Silvana Tesei, Giulia Soldŕ, Gianni Pezzoli, Stefano Duga, Stefano Goldwurm
Parkinsonism Relat Disord 2014 Sep;
PMID: 25249066 [PubMed - as supplied by publisher]

Use of Caenorhabditis elegans as a model to study Alzheimer's disease and other neurodegenerative diseases.
Adanna G Alexander, Vanessa Marfil, Chris Li
Front Genet 2014 ; 5:279
PMID: 25250042 [PubMed - as supplied by publisher]

Indolinone based LRRK2 kinase inhibitors with a key hydrogen bond.
Stefan Göring, Jean-Marc Taymans, Veerle Baekelandt, Boris Schmidt
Bioorg Med Chem Lett 2014 Oct; 24(19):4630-7
PMID: 25219901 [PubMed - as supplied by publisher]

Focusing Brain Therapeutic Interventions in Space and Time for Parkinson's Disease.
S Little, P Brown
Curr Biol 2014 Sep; 24(18):R898-R909
PMID: 25247369 [PubMed - as supplied by publisher]

Are branded and generic extended-release ropinirole formulations equally efficacious? A rater-blinded, switch-over, multicenter study.
Edit Bosnyák, Mihály Herceg, Endre Pál, Zsuzsanna Aschermann, József Janszky, Ildikó Késmárki, Sámuel Komoly, Kázmér Karádi, Tamás Dóczi, Ferenc Nagy, Norbert Kovács
Parkinsons Dis 2014 ; 2014:158353
PMID: 25247107 [PubMed - as supplied by publisher]

Influence of propofol and fentanyl on deep brain stimulation of the subthalamic nucleus.
Wonki Kim, In Ho Song, Yong Hoon Lim, Mi-Ryoung Kim, Young Eun Kim, Jae Ha Hwang, In Keyoung Kim, Sang Woo Song, Jin Wook Kim, Woong-Woo Lee, Han-Joon Kim, Cheolyoung Kim, Hee Chan Kim, In Young Kim, Hee Pyoung Park, Dong Gyu Kim, Beom Seok Jeon, Sun Ha Paek
J Korean Med Sci 2014 Sep; 29(9):1278-86
PMID: 25246748 [PubMed - as supplied by publisher]

Supporting clinical decision making during deep brain stimulation surgery by means of a stochastic dynamical model.
Sofia D Karamintziou, George L Tsirogiannis, Pantelis G Stathis, George A Tagaris, Efstathios J Boviatsis, Damianos E Sakas, Konstantina S Nikita
J Neural Eng 2014 Oct; 11(5):056019
PMID: 25241917 [PubMed - as supplied by publisher]

The toxic effect of manganese on the acetylcholinesterase activity in rat brains.
Vahid Yousefi Babadi, Leila Sadeghi, Kobra Shirani, Ali Akbar Malekirad, Mohammad Rezaei
J Toxicol 2014 ; 2014:946372
PMID: 25246936 [PubMed - as supplied by publisher]

Yokukan-san: a review of the evidence for use of this Kampo herbal formula in dementia and psychiatric conditions.
Hideki Okamoto, Masaomi Iyo, Keigo Ueda, Cheolsun Han, Yoshiro Hirasaki, Takao Namiki
Neuropsychiatr Dis Treat 2014 ; 10:1727-42
PMID: 25246794 [PubMed - as supplied by publisher]

Comparison of voluntary and reflex cough effectiveness in Parkinson's disease.
Karen Wheeler Hegland, Michelle S Troche, Alexandra E Brandimore, Paul W Davenport, Michael S Okun
Parkinsonism Relat Disord 2014 Sep;
PMID: 25246315 [PubMed - as supplied by publisher]

Interdisciplinary teamwork for the treatment of people with Parkinson's disease and their families.
Nir Giladi, Yael Manor, Ariela Hilel, Tanya Gurevich
Curr Neurol Neurosci Rep 2014 Nov; 14(11):493
PMID: 25245121 [PubMed - as supplied by publisher]

LRRK2 G2385R and R1628P Mutations Are Associated with an Increased Risk of Parkinson's Disease in the Malaysian Population.
Aroma Agape Gopalai, Shen-Yang Lim, Jing Yi Chua, Shelisa Tey, Thien Thien Lim, Norlinah Mohamed Ibrahim, Ai Huey Tan, Gaik Bee Eow, Zariah Abdul Aziz, Santhi Datuk Puvanarajah, Shanthi Viswanathan, Irene Looi, Soo Kun Lim, Li Ping Tan, Yip Boon Chong, Chong Tin Tan, Yi Zhao, E K Tan, Azlina Ahmad-Annuar
Biomed Res Int 2014 ; 2014:867321
PMID: 25243190 [PubMed - as supplied by publisher]

The relationship of leukoaraiosis and the clinical severity of vascular Parkinsonism.
Ying-Fa Chen, Yu-Lung Tseng, Min-Yu Lan, Shun-Lon Lai, Chen-San Su, Jia-Shou Liu, Yung-Yee Chang
J Neurol Sci 2014 Sep;
PMID: 25240444 [PubMed - as supplied by publisher]

Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection.
Robert A Hauser, Stuart Isaacson, Thomas Clinch,
Parkinsonism Relat Disord 2014 Aug;
PMID: 25239603 [PubMed - as supplied by publisher]

Treatment of frontotemporal dementia.
Richard M Tsai, Adam L Boxer
Curr Treat Options Neurol 2014 Nov; 16(11):319
PMID: 25238733 [PubMed - as supplied by publisher]

Parkin (PARK 2) Mutations Are Rare in Czech Patients with Early-Onset Parkinson's Disease.
Ondrej Fiala, Daniela Zahorakova, Lenka Pospisilova, Jana Kucerova, Milada Matejckova, Pavel Martasek, Jan Roth, Evzen Ruzicka
PLoS One 2014 ; 9(9):e107585
PMID: 25238391 [PubMed - as supplied by publisher]

Perceptual decision-making in patients with Parkinson's disease.
Atbin Djamshidian, Sean S O'Sullivan, Andrew D Lawrence, Thomas Foltynie, Iciar Aviles-Olmos, Nadia Magdalinou, Alessandro Tomassini, Thomas T Warner, Andrew J Lees, Bruno B Averbeck
J Psychopharmacol 2014 Sep;
PMID: 25237123 [PubMed - as supplied by publisher]

Curcumin's Neuroprotective Efficacy in Drosophila Model of Idiopathic Parkinson's Disease is Phase Specific: Implication of its Therapeutic Effectiveness.
Limamanen Phom, Bovito Achumi, Debasmita Pankaj Alone, Murali Muralidhara, Sarat Chandra Yenisetti
Rejuvenation Res 2014 Sep;
PMID: 25238331 [PubMed - as supplied by publisher]

Acoustic characteristics of the Lombard effect from talkers with Parkinson's disease.
Rahul Shrivastav, Mark D Skowronski, Lisa M Kopf, Brad Rakerd
J Acoust Soc Am 2014 Apr; 135(4):2426
PMID: 25236124 [PubMed - as supplied by publisher]

Tongue shape complexity for liquids in Parkinsonian speech.
Doug H Whalen, Katherine M Dawson, Micalle Carl, Khalil Iskarous
J Acoust Soc Am 2014 Apr; 135(4):2389
PMID: 25235958 [PubMed - as supplied by publisher]

Production and perception of the English sibilants /s/ and /?/ in persons with Parkinson's disease.
Yu-Wen Chen, Peter J Watson
J Acoust Soc Am 2014 Apr; 135(4):2294
PMID: 25235599 [PubMed - as supplied by publisher]

Effects of speaking mode (clear, habitual, slow speech) on vowels of individuals with Parkinson's disease.
Rebekah A Buccheri, Douglas H Whalen, Winifred Strange, Nancy S McGarr, Lawrence J Raphael
J Acoust Soc Am 2014 Apr; 135(4):2294
PMID: 25235597 [PubMed - as supplied by publisher]

Resting state cortical oscillations of PD patients without and with Subthalamic deep brain stimulation, a MEG study.
Chunyan Cao, Dianyou Li, Tianxiao Jiang, Nuri Firat Ince, Shikun Zhan, Jing Zhang, Zhiyi Sha, Bomin Sun
J Clin Neurophysiol 2014 Sep;
PMID: 25233246 [PubMed - as supplied by publisher]

Beta-coupled high-frequency activity and Beta-locked neuronal spiking in the subthalamic nucleus of Parkinson's disease.
Andrew I Yang, Nora Vanegas, Codrin Lungu, Kareem A Zaghloul
J Neurosci 2014 Sep; 34(38):12816-27
PMID: 25232117 [PubMed - as supplied by publisher]

Japan stem-cell trial stirs envy.
Sara Reardon, David Cyranoski
Nature 2014 Sep; 513(7518):287-8
PMID: 25230622 [PubMed - as supplied by publisher]

Mutant of leucine-rich repeat kinase 2 is not associated with non-motor symptoms in Chinese Parkinson's disease patients.
Maolin Hao, Ning Pan, Qinghua Zhang, Xiaohong Wang
Int J Clin Exp Med 2014 ; 7(8):2253-7
PMID: 25232417 [PubMed - as supplied by publisher]

Cholinergic System Dysfunction and Neurodegenerative Diseases: Cause or Effect?
A M Tata, L Velluto, C D'Angelo, M Reale
CNS Neurol Disord Drug Targets 2014 Sep;
PMID: 25230223 [PubMed - as supplied by publisher]

Computational Study of Human Tyrosine Hydroxylase Mutants to Uphold [4-(Propan-2-yl) Phenyl]Carbamic Acid as a Potential Inhibitor.
M S Nawaz, Z Parveen, L Wang, S Rashid, M Q Fatmi, M A Kamal
CNS Neurol Disord Drug Targets 2014 Sep;
PMID: 25230230 [PubMed - as supplied by publisher]

The Impact of Dementia Development Concurrent with Parkinson's Disease: A New Perspective.
A Russell, A Drozdova, W Wang, M Thomas
CNS Neurol Disord Drug Targets 2014 Sep;
PMID: 25230219 [PubMed - as supplied by publisher]

Unique Functional and Structural Properties of the LRRK2 ATP-Binding Pocket.
Zhiyong Liu, Robert A Galemmo, Kyle B Fraser, Mark S Moehle, Saurabh Sen, Laura A Volpicelli-Daley, Lawrence J DeLucas, Larry J Ross, Jacob Valiyaveettil, Omar Moukha-Chafiq, Ashish K Pathak, Sam Ananthan, Hollis Kezar, E Lucile White, Vandana Gupta, Joseph A Maddry, Mark J Suto, Andrew B West
J Biol Chem 2014 Sep;
PMID: 25228699 [PubMed - as supplied by publisher]

Early-onset Parkinson's disease due to PINK1 p.Q456X mutation - Clinical and functional study.
Joanna Siuda, Barbara Jasinska-Myga, Magdalena Boczarska-Jedynak, Grzegorz Opala, Fabienne C Fiesel, Elisabeth L Moussaud-Lamodičre, Leslie A Scarffe, Valina L Dawson, Owen A Ross, Wolfdieter Springer, Ted M Dawson, Zbigniew K Wszolek
Parkinsonism Relat Disord 2014 Sep;
PMID: 25226871 [PubMed - as supplied by publisher]

Protective role of olesoxime against wild type alpha-synuclein-induced toxicity in human neuronally differentiated SHSY-5Y cells.
C Gouarné, J Tracz, M Giraudon Paoli, V Deluca, M Seimandi, G Tardif, M Xilouri, L Stefanis, T Bordet, R M Pruss
Br J Pharmacol 2014 Sep;
PMID: 25220617 [PubMed - as supplied by publisher]

Mutations in Niemann Pick type C gene are risk factor for Alzheimer's disease.
Nikola Kresojevi?, Valerija Dobri?i?, Marina Svetel, Vladimir Kosti?
Med Hypotheses 2014 Sep;
PMID: 25220527 [PubMed - as supplied by publisher]

Prion-like Mechanisms in the Pathogenesis of Tauopathies and Synucleinopathies.
Michel Goedert, Ben Falcon, Florence Clavaguera, Markus Tolnay
Curr Neurol Neurosci Rep 2014 Nov; 14(11):495
PMID: 25218483 [PubMed - as supplied by publisher]

The role of transcriptional control in multiple system atrophy.
Jieqiong Chen, James D Mills, Glenda M Halliday, Michael Janitz
Neurobiol Aging 2014 Aug;
PMID: 25218777 [PubMed - as supplied by publisher]

Transgenic Rodent Models to Study Alpha-Synuclein Pathogenesis, with a Focus on Cognitive Deficits.
Asa Hatami, Marie-Francoise Chesselet
Curr Top Behav Neurosci 2014 Sep;
PMID: 25218491 [PubMed - as supplied by publisher]

Stimulation of the pedunculopontine nucleus area in Parkinson's disease: effects on speech and intelligibility.
Serge Pinto, Murielle Ferraye, Robert Espesser, Valérie Fraix, Audrey Maillet, Jennifer Guirchoum, Deborah Layani-Zemour, Alain Ghio, Stéphan Chabardčs, Pierre Pollak, Bettina Debű
Brain 2014 Oct; 137(Pt 10):2759-72
PMID: 25080284 [PubMed - as supplied by publisher]

Short Mitochondrial ARF Triggers Parkin/PINK1-Dependent Mitophagy.
Karl Grenier, Maria Kontogiannea, Edward A Fon
J Biol Chem 2014 Sep;
PMID: 25217637 [PubMed - as supplied by publisher]

USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin.
Thomas M Durcan, Matthew Y Tang, Joëlle R Pérusse, Eman A Dashti, Miguel A Aguileta, Gian-Luca McLelland, Priti Gros, Thomas A Shaler, Denis Faubert, Benoit Coulombe, Edward A Fon
EMBO J 2014 Sep;
PMID: 25216678 [PubMed - as supplied by publisher]

Clinical trials in Huntington's disease: Interventions in early clinical development and newer methodological approaches.
Cristina Sampaio, Beth Borowsky, Ralf Reilmann
Mov Disord 2014 Sep; 29(11):1419-28
PMID: 25216371 [PubMed - as supplied by publisher]

A familial form of parkinsonism, dementia, and motor neuron disease: A longitudinal study.
Shinsuke Fujioka, Bradley F Boeve, Joseph E Parisi, Pawel Tacik, Naoya Aoki, Audrey J Strongosky, Matt Baker, Monica Sanchez-Contreras, Owen A Ross, Rosa Rademakers, Vesna Sossi, Dennis W Dickson, A Jon Stoessl, Zbigniew K Wszolek
Parkinsonism Relat Disord 2014 Aug;
PMID: 25175602 [PubMed - as supplied by publisher]

Identification of a common founder couple for 40 South African Afrikaner families with Parkinson's disease.
Gerhard Geldenhuys, Brigitte Glanzmann, Debbie Lombard, Sihaam Boolay, Jonathan Carr, Soraya Bardien
S Afr Med J 2014 Jun; 104(6):413-9
PMID: 25214250 [PubMed - as supplied by publisher]

Loudness perception and speech intensity control in Parkinson's disease.
Jenna P Clark, Scott G Adams, Allyson D Dykstra, Shane Moodie, Mandar Jog
J Commun Disord 2014 Aug;
PMID: 25194745 [PubMed - as supplied by publisher]

Risk of Aspiration in Care Home Residents and Associated Factors.
Claar D van der Maarel-Wierink, Gert-Jan van der Putten, Luc M J De Visschere, Ewald M Bronkhorst, Cees de Baat, Jos M G A Schols
J Gerontol Nurs 2014 Aug; :1-6
PMID: 25154055 [PubMed - as supplied by publisher]

Speech-related fatigue and fatigability in Parkinson's disease.
Matthew J Makashay, Kevin R Cannard, Nancy Pearl Solomon
Clin Linguist Phon 2014 Aug; :1-19
PMID: 25152085 [PubMed - as supplied by publisher]

Functional outcomes associated with expiratory muscle strength training: narrative review.
Helena Laciuga, John C Rosenbek, Paul W Davenport, Christine M Sapienza
J Rehabil Res Dev 2014 ; 51(4):535-46
PMID: 25144167 [PubMed - as supplied by publisher]

Articulatory-acoustic vowel space: Application to clear speech in individuals with Parkinson disease.
Jason A Whitfield, Alexander M Goberman
J Commun Disord 2014 Jul;
PMID: 25074511 [PubMed - as supplied by publisher]

Collection and analysis of a Parkinson speech dataset with multiple types of sound recordings.
Betul Erdogdu Sakar, M Erdem Isenkul, C Okan Sakar, Ahmet Sertbas, Fikret Gurgen, Sakir Delil, Hulya Apaydin, Olcay Kursun
IEEE J Biomed Health Inform 2013 Jul; 17(4):828-34
PMID: 25055311 [PubMed - as supplied by publisher]