Adjust Text Size:change font sizechange font sizechange font sizechange font sizechange font sizechange font size

Featured Research

Can we predict who is at risk of facing cognitive issues in PD and address them earlier? These are the questions being pursued by Dr. Goldman of the PDF Research Center at Rush University Medical Center.

Learn More

PDF Grant Programs

Are you interested in furthering Parkinson's science? View PDF's open grant programs.

Learn More


PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.

There was an error retrieving the document. Please try again.

Time- and frequency-domain parameters of heart rate variability and sympathetic skin response in Parkinson's disease.
Walter Maetzler, Marie Karam, Monika Fruhmann Berger, Tanja Heger, Corina Maetzler, Heinz Ruediger, Juliana Bronzova, Patricia Pita Lobo, Joaquim J Ferreira, Tjalf Ziemssen, Daniela Berg
J Neural Transm 2014 Jul;
PMID: 25038873 [PubMed - as supplied by publisher]


The benefits of pramipexole selection in the treatment of Parkinson's disease.
Mine Silindir, A Yekta Ozer
Neurol Sci 2014 Jul;
PMID: 25038745 [PubMed - as supplied by publisher]


Pramipexole but not imipramine or fluoxetine reverses the "depressive-like" behaviour in a rat model of preclinical stages of Parkinson's disease.
Klemencja Berghauzen-Maciejewska, Katarzyna Kuter, Wac?aw Kolasiewicz, Urszula G?owacka, Anna Dziubina, Krystyna Ossowska, Jadwiga Wardas
Behav Brain Res 2014 Sep; 271C:343-353
PMID: 24956561 [PubMed - as supplied by publisher]


Sequential Voluntary Cough and Aspiration or Aspiration Risk in Parkinson's Disease.
Karen Wheeler Hegland, Michael S Okun, Michelle S Troche
Lung 2014 Aug; 192(4):601-608
PMID: 24792231 [PubMed - as supplied by publisher]


Intensive Rehabilitation Treatment in Early Parkinson's Disease: A Randomized Pilot Study With a 2-Year Follow-up.
Giuseppe Frazzitta, Roberto Maestri, Gabriella Bertotti, Giulio Riboldazzi, Natalia Boveri, Michele Perini, Davide Uccellini, Marinella Turla, Cristoforo Comi, Gianni Pezzoli, M Felice Ghilardi
Neurorehabil Neural Repair 2014 Jul;
PMID: 25038064 [PubMed - as supplied by publisher]


CNB-001, a novel pyrazole derivative mitigates motor impairments associated with neurodegeneration via suppression of neuroinflammatory and apoptotic response in experimental Parkinson's disease mice.
Richard L Jayaraj, Namasivayam Elangovan, Chinnasamy Dhanalakshmi, Thamilarasan Manivasagam, Musthafa Mohamed Essa
Chem Biol Interact 2014 Jul; 220C:149-157
PMID: 24995576 [PubMed - as supplied by publisher]


Preventing ?-synuclein aggregation: The role of the small heat-shock molecular chaperone proteins.
Dezerae Cox, John A Carver, Heath Ecroyd
Biochim Biophys Acta 2014 Jun; 1842(9):1830-1843
PMID: 24973551 [PubMed - as supplied by publisher]


Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.
Nina Daschil, Christian Humpel
Brain Res 2014 Jul;
PMID: 25038562 [PubMed - as supplied by publisher]


Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice.
Marusela Oliveras-Salvá, Francesca Macchi, Valérie Coessens, Angélique Deleersnijder, Melanie Gérard, Anke Van der Perren, Chris Van den Haute, Veerle Baekelandt
Neurobiol Aging 2014 Jun;
PMID: 25037286 [PubMed - as supplied by publisher]


Naltrexone for impulse control disorders in Parkinson disease: A placebo-controlled study.
Kimberly Papay, Sharon X Xie, Matthew Stern, Howard Hurtig, Andrew Siderowf, John E Duda, James Minger, Daniel Weintraub
Neurology 2014 Jul;
PMID: 25037206 [PubMed - as supplied by publisher]


(6aR)-11-Amino-N-propyl-noraporphine, a new dopamine D2 and serotonin 5-HT1A dual agonist, elicits potent antiparkinsonian action and attenuates levodopa-induced dyskinesia in a 6-OHDA-lesioned rat model of Parkinson's disease.
Rui Zhao, Weijian Lu, Xing Fang, Lin Guo, Zhi Yang, Na Ye, Jiahao Zhao, Zhili Liu, Jia Jia, Longtai Zheng, Bin Zhao, Ao Zhang, Xuechu Zhen
Pharmacol Biochem Behav 2014 Jun; 124C:204-210
PMID: 24955866 [PubMed - as supplied by publisher]


A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy.
Franziska Richter, Sheila M Fleming, Melanie Watson, Vincent Lemesre, Lee Pellegrino, Brian Ranes, Chunni Zhu, Farzad Mortazavi, Caitlin K Mulligan, Pedrom C Sioshansi, Sindalana Hean, Krystal De La Rosa, Richie Khanna, John Flanagan, David J Lockhart, Brandon A Wustman, Sean W Clark, Marie-Françoise Chesselet
Neurotherapeutics 2014 Jul;
PMID: 25037721 [PubMed - as supplied by publisher]


New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases.
Joy Mitra, Erika N Guerrero, Pavana M Hegde, Haibo Wang, Istvan Boldogh, Kosagi Sharaf Rao, Sankar Mitra, Muralidhar L Hegde
Biomolecules 2014 ; 4(3):678-703
PMID: 25036887 [PubMed - as supplied by publisher]


Analysis of volatile organic compounds in rats with dopaminergic lesion: Possible application for early detection of Parkinson's disease.
S Khatib, J P M Finberg, F Artoul, Y Lavner, S Mahmood, U Tisch, H Haick, Y Aluf, J Vaya
Neurochem Int 2014 Jul;
PMID: 25034982 [PubMed - as supplied by publisher]


G2019S LRRK2 mutant fibroblasts from Parkinson's disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy.
Sokhna M S Yakhine-Diop, José M Bravo-San Pedro, Rubén Gómez-Sánchez, Elisa Pizarro-Estrella, Mario Rodríguez-Arribas, Vicente Climent, Ana Aiastui, Adolfo López de Munain, José M Fuentes, Rosa A González-Polo
Toxicology 2014 Jul; 324C:1-9
PMID: 25017139 [PubMed - as supplied by publisher]


Endothelin-1: A potential pathological factor in Parkinson's disease? -From endoplasmic reticulum stress to beyond.
Arjun Jain
J Neurol Sci 2014 Jun;
PMID: 24998514 [PubMed - as supplied by publisher]


Parkinson's disease biomarker: a patent evaluation of WO2013153386.
Werner J Geldenhuys, Samir M Abdelmagid, Patrick J Gallegos, Fayez F Safadi
Expert Opin Ther Pat 2014 Aug; 24(8):947-51
PMID: 24962176 [PubMed - as supplied by publisher]


Serotonin Impairment in CSF of PD Patients, without an Apparent Clinical Counterpart.
Enrica Olivola, Mariangela Pierantozzi, Paola Imbriani, Claudio Liguori, Mario Stampanoni Bassi, Marco Conti, Vincenza D Angelo, Nicola Biagio Mercuri, Alessandro Stefani
PLoS One 2014 ; 9(7):e101763
PMID: 25036938 [PubMed - as supplied by publisher]


Wetting the whistle: neurotropic factor improves salivary function.
Adam Swick, Randall J Kimple
J Clin Invest 2014 Jul; :1-3
PMID: 25036702 [PubMed - as supplied by publisher]


Recognition and Treatment of Depressive Symptoms in Parkinson's Disease: The NPF Dataset.
Danny Bega, Sam S Wu, Qinglin Pei, Peter N Schmidt, Tanya Simuni
J Parkinsons Dis 2014 Jul;
PMID: 25035310 [PubMed - as supplied by publisher]


The modern pre-levodopa era of Parkinson's disease: insights into motor complications from sub-Saharan Africa.
Roberto Cilia, Albert Akpalu, Fred Stephen Sarfo, Momodou Cham, Marianna Amboni, Emanuele Cereda, Margherita Fabbri, Patrick Adjei, John Akassi, Alba Bonetti, Gianni Pezzoli
Brain 2014 Jul;
PMID: 25034897 [PubMed - as supplied by publisher]


Association of Catechol-O-Methyltransferase and monoamine oxidase B gene polymorphisms with motor complications in parkinson's disease in a Chinese population.
Hongying Hao, Ming Shao, Jing An, Chushuang Chen, Xiuli Feng, Shu Xie, Zhuqin Gu, Piu Chan,
Parkinsonism Relat Disord 2014 Jul;
PMID: 25034874 [PubMed - as supplied by publisher]


The ?7 nicotinic receptor agonist ABT-107 decreases L-dopa-induced dyskinesias in parkinsonian monkeys.
Danhui Zhang, Matthew McGregor, Michael W Decker, Maryka Quik
J Pharmacol Exp Ther 2014 Jul;
PMID: 25034405 [PubMed - as supplied by publisher]


Sleep disturbance and cognitive disorder: epidemiological analysis in a cohort of 263 patients.
Michele Pistacchi, Manuela Gioulis, Franco Contin, Flavio Sanson, Sandro Zambito Marsala
Neurol Sci 2014 Jul;
PMID: 25034185 [PubMed - as supplied by publisher]


Tetranectin Knockout Mice Develop Features of Parkinson Disease.
Er-Song Wang, Xiao-Ping Zhang, Hui-Bin Yao, Gan Wang, Shi-Wen Chen, Wen-Wei Gao, Hai-Jun Yao, Yi-Rui Sun, Cai-Hua Xi, Yao-Dong Ji
Cell Physiol Biochem 2014 Jul; 34(2):277-287
PMID: 25033953 [PubMed - as supplied by publisher]


Balance asymmetry in Parkinson's disease and its contribution to freezing of gait.
Tjitske A Boonstra, Jeroen P P van Vugt, Herman van der Kooij, Bastiaan R Bloem
PLoS One 2014 ; 9(7):e102493
PMID: 25032994 [PubMed - as supplied by publisher]


Network modulation following sham surgery in Parkinson's disease.
Ji Hyun Ko, Andrew Feigin, Paul J Mattis, Chris C Tang, Yilong Ma, Vijay Dhawan, Matthew J During, Michael G Kaplitt, David Eidelberg
J Clin Invest 2014 Jul;
PMID: 25036712 [PubMed - as supplied by publisher]


A brain network response to sham surgery.
Mariya V Cherkasova, A Jon Stoessl
J Clin Invest 2014 Jul; :1-4
PMID: 25036701 [PubMed - as supplied by publisher]


Short Communication Huwe1 as a therapeutic target for neural injury.
J Zhou, Q Liu, M Mao, Y Tong
Genet Mol Res 2014 ; 13(2):4320-4325
PMID: 25036176 [PubMed - as supplied by publisher]


Impulsive and Compulsive Behaviors in Parkinson Study Group (PSG) Centers Performing Deep Brain Stimulation Surgery.
Nawaz Hack, Umer Akbar, Amanda Thompson-Avila, Sarah M Fayad, Erin M Hastings, Elena Moro, Kelsey Nestor, Herbert Ward, Michele York, Michael S Okun
J Parkinsons Dis 2014 Jul;
PMID: 25035311 [PubMed - as supplied by publisher]


192?Stereotactic striatal injection of a regulated glial derived neurotrophic factor expression system: preclinical testing in a primate model.
Seth Franklin Oliveria, Kelly D Foote, Ronald Mandel
Neurosurgery 2014 Aug; 61 Suppl 1:223-4
PMID: 25032643 [PubMed - as supplied by publisher]


171?An investigation of the effects of subthalamic deep brain stimulation on thermal and mechanical thresholds in parkinsonian rats.
Lucy Gee, Joannalee C Campbell, Damian Shin, Julie G Pilitsis
Neurosurgery 2014 Aug; 61 Suppl 1:216
PMID: 25032622 [PubMed - as supplied by publisher]


Safety overview of FDA-approved medications for the treatment of the motor symptoms of Parkinson's disease.
Michele A Faulkner
Expert Opin Drug Saf 2014 Aug; 13(8):1055-69
PMID: 24962891 [PubMed - as supplied by publisher]


7-Ketocholesterol-Induced Inflammation Signals Mostly through the TLR4 Receptor Both In Vitro and In Vivo.
Jiahn-Dar Huang, Juan Amaral, Jung Wha Lee, Ignacio R Rodriguez
PLoS One 2014 ; 9(7):e100985
PMID: 25036103 [PubMed - as supplied by publisher]


SG2NA recruits DJ-1 and Akt into the mitochondria and membrane to protect cells from oxidative damage.
Goutam Kumar Tanti, Shyamal K Goswami
Free Radic Biol Med 2014 Jul;
PMID: 25035075 [PubMed - as supplied by publisher]


Association between vitamin D receptor gene polymorphisms and susceptibility to Parkinson's disease: A meta-analysis.
Zi-Teng Zhang, Yi-Chuan He, Xiu-Juan Ma, Dian-You Li, Guo-Cai Lu
Neurosci Lett 2014 Jun; 578C:122-127
PMID: 24993298 [PubMed - as supplied by publisher]


Genetic, Structural, and Molecular Insights into the Function of Ras of Complex Proteins Domains.
Laura Civiero, Sybille Dihanich, Patrick A Lewis, Elisa Greggio
Chem Biol 2014 Jul; 21(7):809-818
PMID: 24981771 [PubMed - as supplied by publisher]


'Neuroinflammation' differs categorically from inflammation: transcriptomes of Alzheimer's disease, Parkinson's disease, schizophrenia and inflammatory diseases compared.
Michaela D Filiou, Ahmed Shamsul Arefin, Pablo Moscato, Manuel B Graeber
Neurogenetics 2014 Aug; 15(3):201-12
PMID: 24928144 [PubMed - as supplied by publisher]


Nonmotor signs of Parkinson's disease].
Zh Nevrol Psikhiatr Im S S Korsakova 2014 ; 114(5):81-5
PMID: 25035883 [PubMed - as supplied by publisher]


Neuroimaging characteristics of dementia with Lewy bodies.
Elijah Mak, Li Su, Guy B Williams, John T O'Brien
Alzheimers Res Ther 2014 ; 6(2):18
PMID: 25031634 [PubMed - as supplied by publisher]


Protein recycling pathways in neurodegenerative diseases.
Faisal Fecto, Y Taylan Esengul, Teepu Siddique
Alzheimers Res Ther 2014 ; 6(2):13
PMID: 25031631 [PubMed - as supplied by publisher]


Brain: Positron Emission Tomography Tracers Beyond [(18)F]Fluorodeoxyglucose.
Tarun Singhal, Abass Alavi, Chun K Kim
PET Clin 2014 Jul; 9(3):267-276
PMID: 25030390 [PubMed - as supplied by publisher]


Clinical profile of Parkinson's disease in the Gumei community of Minhang district, Shanghai.
Kangyong Liu, Zhaohua Gu, Liang Dong, Liwei Shen, Yinyi Sun, Ting Zhang, Nan Shi, Qian Zhang, Wei Zhang, Meizhen Zhao, Xiaojiang Sun
Clinics (Sao Paulo) 2014 Jul; 69(7):457-63
PMID: 25029576 [PubMed - as supplied by publisher]


Time and frequency-dependent modulation of local field potential synchronization by deep brain stimulation.
Clinton B McCracken, Zelma H T Kiss
PLoS One 2014 ; 9(7):e102576
PMID: 25029468 [PubMed - as supplied by publisher]


Tozadenant (SYN115) in patients with Parkinson's disease who have motor fluctuations on levodopa: a phase 2b, double-blind, randomised trial.
Robert A Hauser, C Warren Olanow, Karl D Kieburtz, Emmanuelle Pourcher, Any Docu-Axelerad, Mark Lew, Olexandr Kozyolkin, Ann Neale, Chris Resburg, Uwe Meya, Christopher Kenney, Stephen Bandak
Lancet Neurol 2014 Aug; 13(8):767-76
PMID: 25008546 [PubMed - as supplied by publisher]


The effects of whole body vibration on mobility and balance in Parkinson disease: a systematic review.
Sharareh Sharififar, Rogelio A Coronado, Sergio Romero, Hassan Azari, Mary Thigpen
Iran J Med Sci 2014 Jul; 39(4):318-26
PMID: 25031483 [PubMed - as supplied by publisher]


Encoding of sequence boundaries in the subthalamic nucleus of patients with Parkinson's disease.
María Herrojo Ruiz, Marco Rusconi, Christof Brücke, John-Dylan Haynes, Thomas Schönecker, Andrea A Kühn
Brain 2014 Jul;
PMID: 25031238 [PubMed - as supplied by publisher]


Tetramethylpyrazine alleviated cytokine synthesis and dopamine deficit and improved motor dysfunction in the mice model of Parkinson's disease.
Hong Zhao, Mei-Ling Xu, Qi Zhang, Zhao-Hui Guo, Ying Peng, Zheng-Yi Qu, Yong-Nan Li
Neurol Sci 2014 Jul;
PMID: 25030124 [PubMed - as supplied by publisher]


Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.
Lars Tatenhorst, Lars Tönges, Kim-Ann Saal, Jan C Koch, Eva M Szeg?, Mathias Bähr, Paul Lingor
J Neuropathol Exp Neurol 2014 Aug; 73(8):770-9
PMID: 25003236 [PubMed - as supplied by publisher]


Involvement of activation of the Nrf2/ARE pathway in protection against 6-OHDA-induced SH-SY5Y cell death by ?-iso-cubebenol.
Sun Young Park, Do Yeon Kim, Jong-Koo Kang, Geuntae Park, Young-Whan Choi
Neurotoxicology 2014 Jul; 44C:160-168
PMID: 24997245 [PubMed - as supplied by publisher]


FBXO7 Y52C Polymorphism as a Potential Protective Factor in Parkinson's Disease.
Chiung-Mei Chen, I-Cheng Chen, Yi-Cheng Huang, Hsueh-Fen Juan, Ying-Lin Chen, Yi-Chun Chen, Chih-Hsin Lin, Li-Ching Lee, Chi-Mei Lee, Guey-Jen Lee-Chen, Yun-Ju Lai, Yih-Ru Wu
PLoS One 2014 ; 9(7):e101392
PMID: 25029497 [PubMed - as supplied by publisher]


Identification of p.Gln858* in ATP13A2 in two EOPD patients and presentation of their clinical features.
Maryam Malakouti-Nejad, Gholam-Ali Shahidi, Mohammad Rohani, Seyed Mehdi Shojaee, Mehrdad Hashemi, Brandy Klotzle, Jian-Bing Fan, Elahe Elahi
Neurosci Lett 2014 Jun; 577C:106-111
PMID: 24949580 [PubMed - as supplied by publisher]


Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinations.
Sandra A Jacobson, Trisha Morshed, Brittany N Dugger, Thomas G Beach, Joseph G Hentz, Charles H Adler, Holly A Shill, Marwan N Sabbagh, Christine M Belden, Lucia I Sue, John N Caviness, Chengcheng Hu,
Parkinsonism Relat Disord 2014 Jun;
PMID: 25027359 [PubMed - as supplied by publisher]


Activities of daily living, depression, and quality of life in Parkinson's disease.
Blake J Lawrence, Natalie Gasson, Robert Kane, Romola S Bucks, Andrea M Loftus
PLoS One 2014 ; 9(7):e102294
PMID: 25025280 [PubMed - as supplied by publisher]


Influence of the Nonergot Dopamine Agonist Piribedil on Vigilance in Patients With Parkinson Disease and Excessive Daytime Sleepiness (PiViCog-PD): An 11-Week Randomized Comparison Trial Against Pramipexole and Ropinirole.
Karla Eggert, Christian Ohlwein, Jan Kassubek, Martin Wolz, Andreas Kupsch, Andres Ceballos-Baumann, Reinhard Ehret, Udo Polzer, Fabian Klostermann, Johannes Schwarz, Gerd Fuchs, Wolfgang Jost, Anita Albert, Anja Haag, Anke Hermsen, Karin Lohmüller, Katrin Kuhn, Martina Wangemann, Wolfgang H Oertel,
Clin Neuropharmacol 2014 Jul-Aug; 37(4):116-22
PMID: 24992083 [PubMed - as supplied by publisher]


Pharmacokinetics of Levodopa in Patients With Parkinson Disease and Motor Fluctuations Depending on the Presence of Helicobacter pylori Infection.
Ewa Naro?a?ska, Monika Bia?ecka, Urszula Adamiak-Giera, Barbara Gawro?ska-Szklarz, Witold So?tan, Micha? Schinwelski, Piotr Robowski, Mariusz H Madali?ski, Jaros?aw S?awek
Clin Neuropharmacol 2014 Jul-Aug; 37(4):96-9
PMID: 24992088 [PubMed - as supplied by publisher]


Liquid melevodopa versus standard levodopa in patients with Parkinson disease and small intestinal bacterial overgrowth.
Alfonso Fasano, Francesco Bove, Maurizio Gabrielli, Enzo Ragazzoni, Serena Fortuna, Annalisa Tortora, Maria Assunta Zocco, Stefano Marconi, Antonio Gasbarrini, Anna Rita Bentivoglio
Clin Neuropharmacol 2014 Jul-Aug; 37(4):91-5
PMID: 24992085 [PubMed - as supplied by publisher]


Antimetastatic Effects of Blocking PD-1 and the Adenosine A2A Receptor.
Deepak Mittal, Arabella Young, Kimberley Stannard, Michelle Yong, Michele W L Teng, Bertrand Allard, John Stagg, Mark J Smyth
Cancer Res 2014 Jul; 74(14):3652-8
PMID: 24986517 [PubMed - as supplied by publisher]


The association between the LRRK2 G2385R variant and the risk of Parkinson's disease: a meta-analysis based on 23 case-control studies.
Cheng-Long Xie, Jia-Lin Pan, Wen-Wen Wang, Yu Zhang, Su-Fang Zhang, Jing Gan, Zhen-Guo Liu
Neurol Sci 2014 Jul;
PMID: 25027012 [PubMed - as supplied by publisher]


Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson's disease cell and mouse models.
Tianxia Li, Dejun Yang, Shijun Zhong, Joseph M Thomas, Fengtian Xue, Jingnan Liu, Lingbo Kong, Pamela Voulalas, Hazem E Hassan, Jae-Sung Park, Alexander D MacKerell, Wanli W Smith
Hum Mol Genet 2014 Jul;
PMID: 24993787 [PubMed - as supplied by publisher]


Telemonitoring of patients with Parkinson's disease using inertia sensors.
N E Piro, L Baumann, M Tengler, L Piro, R Blechschmidt-Trapp
Appl Clin Inform 2014 ; 5(2):503-11
PMID: 25024764 [PubMed - as supplied by publisher]


Cardiovascular medication burden in dementia disorders: a nationwide study of 19,743 dementia patients in the Swedish Dementia Registry.
Pavla Cermakova, Seyed-Mohammad Fereshtehnejad, Kristina Johnell, Bengt Winblad, Maria Eriksdotter, Dorota Religa
Alzheimers Res Ther 2014 ; 6(3):34
PMID: 25024749 [PubMed - as supplied by publisher]


The association between chronic obstructive pulmonary disease and Parkinson's disease: a nationwide population-based retrospective cohort study.
C-H Li, W-C Chen, W-C Liao, C-Y Tu, C-L Lin, F-C Sung, C-H Chen, W-H Hsu
QJM 2014 Jul;
PMID: 25024356 [PubMed - as supplied by publisher]


Predictors of dementia in Parkinson's disease; findings from a 5-year prospective study using the SCOPA-COG.
Kangdi Zhu, Jacobus J van Hilten, Johan Marinus
Parkinsonism Relat Disord 2014 Jun;
PMID: 25024059 [PubMed - as supplied by publisher]


Transdermal rotigotine in advanced Parkinson's disease: a randomized, double-blind, placebo-controlled trial.
Masahiro Nomoto, Yoshikuni Mizuno, Tomoyoshi Kondo, Kazuko Hasegawa, Miho Murata, Masahiro Takeuchi, Junji Ikeda, Takayuki Tomida, Nobutaka Hattori
J Neurol 2014 Jul;
PMID: 25022939 [PubMed - as supplied by publisher]


Discovery of Novel-Scaffold Monoamine Transporter Ligands via in Silico Screening with the S1 Pocket of the Serotonin Transporter.
Tammy L Nolan, Laura M Geffert, Benedict J Kolber, Jeffry D Madura, Christopher K Surratt
ACS Chem Neurosci 2014 Jul;
PMID: 25003748 [PubMed - as supplied by publisher]


Effects of Low Doses of Quercetin and Genistein on Oxidation and Carbonylation in Hemoglobin and Myoglobin.
William Y Boadi, Damitea Johnson
J Diet Suppl 2014 Jul;
PMID: 25026201 [PubMed - as supplied by publisher]


Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells.
Julio Cesar Aguila, Alexandra Blak, Joris van Arensbergen, Amaia Sousa, Nerea Vázquez, Ariane Aduriz, Mayela Gayosso, Maria Paz Lopez Mato, Rakel Lopez de Maturana, Eva Hedlund, Kai Sonntag, Rosario Sanchez Pernaute
Stem Cells Transl Med 2014 Jul;
PMID: 25024431 [PubMed - as supplied by publisher]


CNB-001 a Novel Curcumin Derivative, Guards Dopamine Neurons in MPTP Model of Parkinson's Disease.
Richard L Jayaraj, Namasivayam Elangovan, Krishnan Manigandan, Sonu Singh, Shubha Shukla
Biomed Res Int 2014 ; 2014:236182
PMID: 25025041 [PubMed - as supplied by publisher]


Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated ?-synuclein.
Misook Oh, Ji Hoon Lee, Wei Wang, Hui Sun Lee, Woo Sirl Lee, Christopher Burlak, Wonpil Im, Quyen Q Hoang, Hyun-Suk Lim
Proc Natl Acad Sci U S A 2014 Jul;
PMID: 25024216 [PubMed - as supplied by publisher]


Cell-permeable parkin proteins suppress Parkinson disease-associated phenotypes in cultured cells and animals.
Tam Duong, Jaetaek Kim, H Earl Ruley, Daewoong Jo
PLoS One 2014 ; 9(7):e102517
PMID: 25019626 [PubMed - as supplied by publisher]


Parkinson disease: A monoclonal antibody targeting misfolded ?-synuclein has therapeutic potential in Parkinson disease.
Heather Wood
Nat Rev Neurol 2014 Jul;
PMID: 25002110 [PubMed - as supplied by publisher]


HSPA1A-independent suppression of PARK2 C289G protein aggregation by human small heat shock proteins.
Melania Minoia, Corien Grit, Harm H Kampinga
Mol Cell Biol 2014 Jul;
PMID: 25022755 [PubMed - as supplied by publisher]


Advances in pediatric celiac disease.
Tran H Tran
Curr Opin Pediatr 2014 Jul;
PMID: 25022217 [PubMed - as supplied by publisher]


Genomic analysis of the causative agents of coccidiosis in domestic chickens.
Adam James Reid, Damer Peter Blake, Hifzur Rahman Ansari, Karen Billington, Hilary P Browne, Josephine M Bryant, Matthew Dunn, Stacy S Hung, Fumiya Kawahara, Diego Miranda-Saavedra, Tareq Malas, Tobias Mourier, Hardeep Naghra, Mridul Nair, Thomas Dan Otto, Neil David Rawlings, Pierre Rivailler, Alejandro Sanchez-Flores, Mandy Sanders, Chandra Subramaniam, Yea-Ling Tay, Yong Woo, Xikun Wu, Bart Barrell, Paul H Dear, Christian Doerig, Arthur Gruber, Alasdair C Ivens, John Parkinson, Marie-Adčle Rajandream, Martin William Shirley, Kiew-Lan Wan, Matthew Berriman, Fiona M Tomley, Arnab Pain
Genome Res 2014 Jul;
PMID: 25015382 [PubMed - as supplied by publisher]


Tau protein, beta-amyloid1-42 and clusterin CSF levels in the differential diagnosis of Parkinsonian syndrome with dementia.
Hana P?ikrylová Vranová, Eva Hényková, Michaela Kaiserová, Kate?ina Men?íková, Miroslav Va?tík, Jan Mare?, Petr Hlu?tík, Jana Zapletalová, Miroslav Strnad, David Stejskal, Petr Ka?ovský
J Neurol Sci 2014 Aug; 343(1-2):120-4
PMID: 24928081 [PubMed - as supplied by publisher]


Preparing an E-learning-based Speech Therapy (EST) efficacy study: Identifying suitable outcome measures to detect within-subject changes of speech intelligibility in dysarthric speakers.
L J Beijer, A C M Rietveld, M B Ruiter, A C H Geurts
Clin Linguist Phon 2014 Jul; :1-24
PMID: 25025268 [PubMed - as supplied by publisher]


0239? Inducible nitric oxide synthase gene methylation and parkinsonism in manganese-exposed welders0239? Inducible nitric oxide synthase gene methylation and parkinsonism in manganese-exposed welders.
Susan Nielsen, Harvey Checkoway, Susan Criswell, Federico Farin, Brad Racette
Occup Environ Med 2014 Jun; 71 Suppl 1:A32
PMID: 25018322 [PubMed - as supplied by publisher]


1-O-Tigloyl-1-O-deacetylnimbolinin B Inhibits LPS-Stimulated Inflammatory Responses by Suppressing NF-?B and JNK Activation in Microglia Cells.
Li Tao, Fali Zhang, Lili Hao, Jing Wu, Jia Jia, Jiang-Yun Liu, Long Tai Zheng, Xuechu Zhen
J Pharmacol Sci 2014 Jul;
PMID: 25018136 [PubMed - as supplied by publisher]


Acute Changes in Mood Induced by Subthalamic Deep Brain Stimulation in Parkinson Disease Are Modulated by Psychiatric Diagnosis.
Sarah A Eisenstein, William B Dewispelaere, Meghan C Campbell, Heather M Lugar, Joel S Perlmutter, Kevin J Black, Tamara Hershey
Brain Stimul 2014 Jun;
PMID: 25017671 [PubMed - as supplied by publisher]


Depression and Anxiety Following Deep Brain Stimulation in Parkinson's Disease: Systematic Review and Meta-Analysis.
Maria Inęs Couto, Ana Monteiro, Ana Oliveira, Nuno Lunet, Joăo Massano
Acta Med Port 2014 May-Jun; 27(3):372-382
PMID: 25017350 [PubMed - as supplied by publisher]


Diagnostic value of neuropsychological tests in mild cognitive impairment comorbid with Parkinson's disease].
Ilona Laskowska, Andrzej Koczorowski, Dariusz Koziorowski, Ludwika Gawry?
Psychiatr Pol 2014 Mar-Apr; 48(2):331-43
PMID: 25016770 [PubMed - as supplied by publisher]


To move or not to move: Subthalamic deep brain stimulation effects on implicit motor simulation.
Barbara Tomasino, Dario Marin, Roberto Eleopra, Sara Rinaldo, Lettieri Cristian, Mucchiut Marco, Belgrado Enrico, Monica Zanier, Riccardo Budai, Massimo Mondani, Stanislao D'Auria, Miran Skrap, Franco Fabbro
Brain Res 2014 Jul; 1574:14-25
PMID: 24933326 [PubMed - as supplied by publisher]


Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein.
Sudhakar Raja Subramaniam, Laurent Vergnes, Nicholas R Franich, Karen Reue, Marie-Francoise Chesselet
Neurobiol Dis 2014 Jul;
PMID: 25016198 [PubMed - as supplied by publisher]


Altered dopamine homeostasis differentially affects mitochondrial voltage-dependent anion channels turnover.
Tiziana Alberio, Cristina Mammucari, Gianluca D'Agostino, Rosario Rizzuto, Mauro Fasano
Biochim Biophys Acta 2014 Jul;
PMID: 24998333 [PubMed - as supplied by publisher]


Discovery of a benzofuran derivative (MBPTA) as a novel ROCK inhibitor that protects against MPP(+)-induced oxidative stress and cell death in SH-SY5Y cells.
Cheong-Meng Chong, Mingyun Shen, Zhong-Yan Zhou, Peichen Pan, Pui-Man Hoi, Shang Li, Wang Liang, Nana Ai, Lun-Qing Zhang, Cheuk-Wing Li, Huidong Yu, Tingjun Hou, Simon Ming-Yuen Lee
Free Radic Biol Med 2014 Jun;
PMID: 24973649 [PubMed - as supplied by publisher]


The neuroprotective effect of human uncoupling protein 2 (hUCP2) requires cAMP-dependent protein kinase in a toxin model of Parkinson's disease.
Ran-Der Hwang, Lyle Wiemerslage, Christopher J LaBreck, Munzareen Khan, Kavitha Kannan, Xinglong Wang, Xiongwei Zhu, Daewoo Lee, Yih-Woei C Fridell
Neurobiol Dis 2014 Sep; 69:180-91
PMID: 24965893 [PubMed - as supplied by publisher]


Virtual reality walking and dopamine: Opening new doorways to understanding freezing of gait in Parkinson's disease.
E Matar, J M Shine, S L Naismith, S J G Lewis
J Neurol Sci 2014 Jul;
PMID: 25016571 [PubMed - as supplied by publisher]


Clinical features associated with sleep disturbances in Parkinson's disease.
Kari Anne Bjřrnarĺ, Espen Dietrichs, Mathias Toft
Clin Neurol Neurosurg 2014 Jun; 124C:37-43
PMID: 25016237 [PubMed - as supplied by publisher]


Spinal Stimulation for Movement Disorders.
Claire Thiriez, Jean-Marc Gurruchaga, Colette Goujon, Gilles Fénelon, Stéphane Palfi
Neurotherapeutics 2014 Jul;
PMID: 25015323 [PubMed - as supplied by publisher]


Electrical stimuli in the central nervous system microenvironment.
Deanna M Thompson, Abigail N Koppes, John G Hardy, Christine E Schmidt
Annu Rev Biomed Eng 2014 Jul; 16:397-430
PMID: 25014787 [PubMed - as supplied by publisher]


Executive Task Performance under Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease Revisited: The Modulating Influence of Apathy, Depression and Mood].
U Lueken, Y Stankevich, T Goschke, T E Schläpfer, J Koy, H Reichmann, A Storch, M Wolz
Fortschr Neurol Psychiatr 2014 Jul; 82(7):386-93
PMID: 25014201 [PubMed - as supplied by publisher]


Mavoglurant as a treatment for Parkinson's disease.
Dmitry Petrov, Ignacio Pedros, Maria Luisa de Lemos, Mercč Pallŕs, Anna Maria Canudas, Alberto Lazarowski, Carlos Beas-Zarate, Carme Auladell, Jaume Folch, Antoni Camins
Expert Opin Investig Drugs 2014 Aug; 23(8):1165-79
PMID: 24960254 [PubMed - as supplied by publisher]


Suppression of glia maturation factor expression prevents 1-methyl-4-phenylpyridinium (MPP+)-induced loss of mesencephalic dopaminergic neurons.
Mohammad Moshahid Khan, Smita Zaheer, John Nehman, Asgar Zaheer
Neuroscience 2014 Jul;
PMID: 25016212 [PubMed - as supplied by publisher]


Effects of balance and gait training on the recovery of the motor function in an animal model of Parkinson's disease.
Young-Jeoi Yoon, Byung-Hoon Lee
J Phys Ther Sci 2014 Jun; 26(6):905-8
PMID: 25013293 [PubMed - as supplied by publisher]


Gender differences on motor and non-motor symptoms of de novo patients with early Parkinson's disease.
Yang Song, Zhuqin Gu, Jing An, Piu Chan,
Neurol Sci 2014 Jul;
PMID: 25012756 [PubMed - as supplied by publisher]


Development and validation of a new screening questionnaire for dysphagia in early stages of Parkinson's disease.
Janine A Simons, Urban M Fietzek, Annika Waldmann, Tobias Warnecke, Tibor Schuster, Andrés O Ceballos-Baumann
Parkinsonism Relat Disord 2014 Jun;
PMID: 25012695 [PubMed - as supplied by publisher]


Effect of subthalamic nucleus deep brain stimulation on dual-task cognitive and motor performance in isolated dystonia.
Kelly A Mills, Leslie C Markun, Marta San Luciano, Rami Rizk, I Elaine Allen, Caroline A Racine, Philip A Starr, Jay L Alberts, Jill L Ostrem
J Neurol Neurosurg Psychiatry 2014 Jul;
PMID: 25012202 [PubMed - as supplied by publisher]


Imaging the Role of Amyloid in PD Dementia and Dementia with Lewy Bodies.
Stephen N Gomperts
Curr Neurol Neurosci Rep 2014 Aug; 14(8):472
PMID: 25011528 [PubMed - as supplied by publisher]


Comparative efficacy of selegiline versus rasagiline in the treatment of early Parkinson's disease.
S Marconi, T Zwingers
Eur Rev Med Pharmacol Sci 2014 Jul; 18(13):1879-82
PMID: 25010617 [PubMed - as supplied by publisher]


A pilot psychometric study of aberrant salience state in patients with Parkinson's disease and its association with dopamine replacement therapy.
Michele Poletti, Daniela Frosini, Cristina Pagni, Filippo Baldacci, Claudio Lucetti, Paolo Del Dotto, Roberto Ceravolo, Ubaldo Bonuccelli
Neurol Sci 2014 Jul;
PMID: 25012755 [PubMed - as supplied by publisher]


Deep brain stimulation for severe secondary stereotypies.
Amber Stocco, José Fidel Baizabal-Carvallo
Parkinsonism Relat Disord 2014 Jun;
PMID: 25012696 [PubMed - as supplied by publisher]


Impulse control behaviours in patients with Parkinson's disease after subthalamic deep brain stimulation: de novo cases and 3-year follow-up.
P Amami, I Dekker, S Piacentini, F Ferré, L M Romito, A Franzini, E M J Foncke, A Albanese
J Neurol Neurosurg Psychiatry 2014 Jul;
PMID: 25012201 [PubMed - as supplied by publisher]


Spinal Cord Stimulation Exerts Neuroprotective Effects against Experimental Parkinson's Disease.
Aiko Shinko, Takashi Agari, Masahiro Kameda, Takao Yasuhara, Akihiko Kondo, Judith Thomas Tayra, Kenichiro Sato, Tatsuya Sasaki, Susumu Sasada, Hayato Takeuchi, Takaaki Wakamori, Cesario V Borlongan, Isao Date
PLoS One 2014 ; 9(7):e101468
PMID: 25009993 [PubMed - as supplied by publisher]


Intrastriatal GDNF gene transfer by inducible lentivirus vectors protects dopaminergic neurons in a rat model of parkinsonism.
Sha-Sha Chen, Chun Yang, Fei Hao, Chen Li, Tao Lu, Li-Ru Zhao, Wei-Ming Duan
Exp Neurol 2014 Jul;
PMID: 24997241 [PubMed - as supplied by publisher]


Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease.
Scott Ayton, Peng Lei, Paul A Adlard, Irene Volitakis, Robert A Cherny, Ashley I Bush, David I Finkelstein
Mol Neurodegener 2014 Jul; 9(1):27
PMID: 25011704 [PubMed - as supplied by publisher]


The Small Heat Shock Protein HspB8: Role in Nervous System Physiology and Pathology.
M Vicario, S D Skaper, A Negro
CNS Neurol Disord Drug Targets 2014 Jul;
PMID: 25012617 [PubMed - as supplied by publisher]


REM Sleep Behavior and Motor Findings in Parkinson's Disease: A Cross-sectional Analysis.
Abhimanyu Mahajan, Liana S Rosenthal, Charlene Gamaldo, Rachel E Salas, Gregory M Pontone, Arita McCoy, Chizoba Umeh, Zoltan Mari
Tremor Other Hyperkinet Mov (N Y) 2014 ; 4:245
PMID: 25009765 [PubMed - as supplied by publisher]


Neuronal Entropy Depends on the Level of Alertness in the Parkinsonian Globus Pallidus in vivo.
Daniela Sabrina Andres, Daniel Cerquetti, Marcelo Merello, Ruedi Stoop
Front Neurol 2014 ; 5:96
PMID: 25009529 [PubMed - as supplied by publisher]


Do cholinesterase inhibitors work?
Hugh Rickards
J Neurol Neurosurg Psychiatry 2014 Aug; 85(8):e3
PMID: 25009321 [PubMed - as supplied by publisher]


Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.
Dora Games, Elvira Valera, Brian Spencer, Edward Rockenstein, Michael Mante, Anthony Adame, Christina Patrick, Kiren Ubhi, Silke Nuber, Patricia Sacayon, Wagner Zago, Peter Seubert, Robin Barbour, Dale Schenk, Eliezer Masliah
J Neurosci 2014 Jul; 34(28):9441-54
PMID: 25009275 [PubMed - as supplied by publisher]


Correlation Between Impulsivity and Executive Function in Patients With Parkinson Disease Experiencing Depression and Anxiety Symptoms.
Fernanda Colucci Fonoff, Erich Talamoni Fonoff, Egberto Reis Barbosa, Thais Quaranta, Rachael Brant Machado, Daniel Ciampi de Andrade, Manoel Jacobsen Teixeira, Daniel Fuentes
J Geriatr Psychiatry Neurol 2014 Jul;
PMID: 25009159 [PubMed - as supplied by publisher]


Hyper-synchrony despite pathologically-reduced beta oscillations in patients with Parkinson's disease: A pharmaco-magnetoencephalography study.
Elizabeth Heinrichs-Graham, Max J Kurz, Katherine M Becker, Pamela M Santamaria, Howard E Gendelman, Tony W Wilson
J Neurophysiol 2014 Jul;
PMID: 25008416 [PubMed - as supplied by publisher]


ESCRT mediated uptake and degradation of brain targeted ?-synuclein-single chain antibody attenuates neuronal degeneration in vivo.
Brian Spencer, Sharareh Emadi, Paula Desplats, Simona Eleuteri, Sarah Michael, Kori Kosberg, Jay Shen, Edward Rockenstein, Christina Patrick, Anthony Adame, Tania Gonzalez, Michael Sierks, Eliezer Masliah
Mol Ther 2014 Jul;
PMID: 25008355 [PubMed - as supplied by publisher]


Uneven age effects of [(18)F]FP-CIT binding in the striatum of Parkinson's disease.
Chong S Lee, Su-Jeong Kim, Seung Jun Oh, Hye Ok Kim, Sung-Cheol Yun, Doris Doudet, Jae Seung Kim
Ann Nucl Med 2014 Jul;
PMID: 25008292 [PubMed - as supplied by publisher]


Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson's disease.
Ting-Li Dai, Chan Zhang, Fang Peng, Xue-Yuan Niu, Ling Hu, Qiong Zhang, Ying Huang, Ling Chen, Lei Zhang, Weidong Zhu, Yu-Qiang Ding, Ning-Ning Song, Min Liao
Exp Ther Med 2014 Aug; 8(2):384-390
PMID: 25009587 [PubMed - as supplied by publisher]


Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis.
Nicolas Dzamko, Jinxia Zhou, Yue Huang, Glenda M Halliday
Front Mol Neurosci 2014 ; 7:57
PMID: 25009465 [PubMed - as supplied by publisher]


Synucleins regulate the kinetics of synaptic vesicle endocytosis.
Karina J Vargas, Sachin Makani, Taylor Davis, Christopher H Westphal, Pablo E Castillo, Sreeganga S Chandra
J Neurosci 2014 Jul; 34(28):9364-76
PMID: 25009269 [PubMed - as supplied by publisher]


LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site status.
April Reynolds, Elizabeth A Doggett, Steve M Riddle, Connie S Lebakken, R Jeremy Nichols
Front Mol Neurosci 2014 ; 7:54
PMID: 25009464 [PubMed - as supplied by publisher]


PPAR? and PGC-1? as Therapeutic Targets in Parkinson's.
Juan Carlos Corona, Michael R Duchen
Neurochem Res 2014 Jul;
PMID: 25007880 [PubMed - as supplied by publisher]


Do CSF levels of t-Tau, p-Tau and ?1-42 amyloid correlate with dopaminergic system impairment in patients with a clinical diagnosis of Parkinson disease? A (123)I-FP-CIT study in the early stages of the disease.
Agostino Chiaravalloti, Alessandro Stefani, Alessandro Fiorentini, Annamaria Lacanfora, Paolo Stanzione, Orazio Schillaci
Eur J Nucl Med Mol Imaging 2014 Jul;
PMID: 25007849 [PubMed - as supplied by publisher]


Patterns and Predictors of Mental Health Service Utilization in People With Parkinson's Disease.
Lakkhina Troeung, Natalie Gasson, Sarah J Egan
J Geriatr Psychiatry Neurol 2014 Jul;
PMID: 25009156 [PubMed - as supplied by publisher]


"Masters and servants" in parkinsonian gait: a three-dimensional analysis of biomechanical changes sensitive to disease progression.
G Albani, V Cimolin, A Fasano, C Trotti, M Galli, A Mauro
Funct Neurol 2014 Jul; :1-7
PMID: 25006748 [PubMed - as supplied by publisher]


Increased risk of impulse control symptoms in Parkinson's disease with REM sleep behaviour disorder.
M L Fantini, L Macedo, M Zibetti, M Sarchioto, T Vidal, B Pereira, A Marques, B Debilly, P Derost, M Ulla, N Vitello, A Cicolin, L Lopiano, F Durif
J Neurol Neurosurg Psychiatry 2014 Jul;
PMID: 25006210 [PubMed - as supplied by publisher]


Clinicoradiological comparison between vascular parkinsonism and Parkinson's disease.
Thiago Cardoso Vale, Paulo Caramelli, Francisco Cardoso
J Neurol Neurosurg Psychiatry 2014 Jul;
PMID: 25006209 [PubMed - as supplied by publisher]


Association Between Bullous Pemphigoid and Neurologic Diseases: A Case-Control Study.
E Casas-de-la-Asunción, J Ruano-Ruiz, A M Rodríguez-Martín, A Vélez García-Nieto, J C Moreno-Giménez
Actas Dermosifiliogr 2014 Jul;
PMID: 25004905 [PubMed - as supplied by publisher]


Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.
Jose Bras, Rita Guerreiro, Lee Darwent, Laura Parkkinen, Olaf Ansorge, Valentina Escott-Price, Dena G Hernandez, Michael A Nalls, Lorraine N Clark, Lawrence S Honig, Karen Marder, Wiesje M Van Der Flier, Afina Lemstra, Philip Scheltens, Ekaterina Rogaeva, Peter St George-Hyslop, Elisabet Londos, Henrik Zetterberg, Sara Ortega-Cubero, Pau Pastor, Tanis J Ferman, Neill R Graff-Radford, Owen A Ross, Imelda Barber, Anne Braae, Kristelle Brown, Kevin Morgan, Walter Maetzler, Daniela Berg, Claire Troakes, Safa Al-Sarraj, Tammaryn Lashley, Yaroslau Compta, Tamas Revesz, Andrew Lees, Nigel Cairns, Glenda M Halliday, David Mann, Stuart Pickering-Brown, Dennis W Dickson, Andrew Singleton, John Hardy
Hum Mol Genet 2014 Jun;
PMID: 24973356 [PubMed - as supplied by publisher]


Complications related with implanted devices in patients with Parkinson's disease treated with deep brain stimulation. A study of a series of 124 patients over a period of 16 years].
C de Quintana-Schmidt, B Pascual-Sedano, M J Alvarez-Holzapfel, A Gironell, A Leidinger, N Benito, R Rodriguez-Rodriguez, J Molet-Teixido
Rev Neurol 2014 Jul; 59(2):49-56
PMID: 25005315 [PubMed - as supplied by publisher]


Cortico-striatal-thalamic network functional connectivity in hemiparkinsonism.
Federica Agosta, Francesca Caso, Iva Stankovic, Alberto Inuggi, Igor Petrovic, Marina Svetel, Vladimir S Kostic, Massimo Filippi
Neurobiol Aging 2014 Jun;
PMID: 25004890 [PubMed - as supplied by publisher]


A well-refined in vitro model derived from human embryonic stem cell for screening phytochemicals with midbrain dopaminergic differentiation-boosting potential for improving Parkinson's disease.
Wen-Ting Hsieh, Been-Huang Chiang
J Agric Food Chem 2014 Jul; 62(27):6326-36
PMID: 24933592 [PubMed - as supplied by publisher]


Role of Aldehyde Dehydrogenase 2 in 1-Methy-4-Phenylpyridinium Ion-Induced Aldehyde Stress and Cytotoxicity in PC12 Cells.
Ai-Hua Chen, Ping Zhang, Wei-Lan Yin, Li Wang, Wei Zou, Xiao-Qing Tang
Neurochem Res 2014 Jul;
PMID: 25005621 [PubMed - as supplied by publisher]


?-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.
Guowei Yin, Tomas Lopes da Fonseca, Sibylle E Eisbach, Ane Martín Anduaga, Carlo Breda, Maria L Orcellet, Eva M Szeg?, Patricia Guerreiro, Diana Lazaro, Gerhard H Braus, Claudio O Fernandez, Christian Griesinger, Stefan Becker, Roger S Goody, Aymelt Itzen, Flaviano Giorgini, Tiago F Outeiro, Markus Zweckstetter
Neurobiol Dis 2014 Jun;
PMID: 24983211 [PubMed - as supplied by publisher]


Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo.
Kelly M Lohr, Alison I Bernstein, Kristen A Stout, Amy R Dunn, Carlos R Lazo, Shawn P Alter, Minzheng Wang, Yingjie Li, Xueliang Fan, Ellen J Hess, Hong Yi, Laura M Vecchio, David S Goldstein, Thomas S Guillot, Ali Salahpour, Gary W Miller
Proc Natl Acad Sci U S A 2014 Jul; 111(27):9977-82
PMID: 24979780 [PubMed - as supplied by publisher]


Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates.
Gyan Modi, Chandrashekhar Voshavar, Sanjib Gogoi, Mrudang Shah, Tamara Antonio, Maarten E A Reith, Aloke K Dutta
ACS Chem Neurosci 2014 Jul;
PMID: 24960209 [PubMed - as supplied by publisher]


Woman With X-Linked Recessive Dystonia-Parkinsonism: Clue to the Epidemiology of Parkinsonism in Filipino Women?
Aloysius Domingo, Lillian V Lee, Norbert Brüggemann, Karen Freimann, Frank J Kaiser, Roland D G Jamora, Raymond L Rosales, Christine Klein, Ana Westenberger
JAMA Neurol 2014 Jul;
PMID: 25004170 [PubMed - as supplied by publisher]


Pull test performance and correlation with falls risk in Parkinson?s disease.
Renato P Munhoz, Helio A Teive
Arq Neuropsiquiatr 2014 Jul; 0:0
PMID: 25003398 [PubMed - as supplied by publisher]


A 6.4 Mb Duplication of the ?-Synuclein Locus Causing Frontotemporal Dementia and Parkinsonism: Phenotype-Genotype Correlations.
Eleanna Kara, Aoife P Kiely, Christos Proukakis, Nicola Giffin, Seth Love, Jason Hehir, Khadija Rantell, Amelie Pandraud, Dena G Hernandez, Elizabeth Nacheva, Alan M Pittman, Mike A Nalls, Andrew B Singleton, Tamas Revesz, Kailash P Bhatia, Niall Quinn, John Hardy, Janice L Holton, Henry Houlden
JAMA Neurol 2014 Jul;
PMID: 25003242 [PubMed - as supplied by publisher]


Risk factors for visual hallucinations in patients with Parkinson's disease.
Rômulo Lopes Gama, Veralice Meireles Sales de Bruin, Pedro Felipe Carvalhedo de Bruin, Daniel Gurgel Fernandes Távora, Emily Mourăo Soares Lopes, Iago Farias Jorge, Lia Rita Azeredo Bittencourt, Sergio Tufik
Neurol Res 2014 Jul; :1743132814Y0000000418
PMID: 25002179 [PubMed - as supplied by publisher]


The role of neurostimulation in the treatment of neuropathic pain.
Ewa Papu?, Konrad Rejdak
Ann Agric Environ Med 2013 Dec; 0(1):14-7
PMID: 25000835 [PubMed - as supplied by publisher]


Novel AAV-Based Rat Model of Forebrain Synucleinopathy Shows Extensive Pathologies and Progressive Loss of Cholinergic Interneurons.
Patrick Aldrin-Kirk, Marcus Davidsson, Staffan Holmqvist, Jia-Yi Li, Tomas Björklund
PLoS One 2014 ; 9(7):e100869
PMID: 24999658 [PubMed - as supplied by publisher]


Intramuscular injection of ?-synuclein induces CNS ?-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
Amanda N Sacino, Mieu Brooks, Michael A Thomas, Alex B McKinney, Sooyeon Lee, Robert W Regenhardt, Nicholas H McGarvey, Jacob I Ayers, Lucia Notterpek, David R Borchelt, Todd E Golde, Benoit I Giasson
Proc Natl Acad Sci U S A 2014 Jul;
PMID: 25002524 [PubMed - as supplied by publisher]


Chromosome 22q11.2 deletion may contain a locus for recessive early-onset Parkinson's disease.
Kotaro Ogaki, Owen A Ross
Parkinsonism Relat Disord 2014 Jun;
PMID: 25001314 [PubMed - as supplied by publisher]


Behavioral Deficits and Striatal DA Signaling in LRRK2 p.G2019S Transgenic Rats: A Multimodal Investigation Including PET Neuroimaging.
Matthew D Walker, Mattia Volta, Stefano Cataldi, Katherine Dinelle, Dayne Beccano-Kelly, Lise Munsie, Rick Kornelsen, Chenoa Mah, Patrick Chou, Kimberly Co, Jaskaran Khinda, Marta Mroczek, Sabrina Bergeron, Katrina Yu, Li Ping Cao, Natalja Funk, Thomas Ott, Dagmar Galter, Olaf Riess, Saskia Biskup, Austen J Milnerwood, A Jon Stoessl, Matthew J Farrer, Vesna Sossi
J Parkinsons Dis 2014 Jul;
PMID: 25000966 [PubMed - as supplied by publisher]


Wet Voice as a Sign of Penetration/Aspiration in Parkinson's Disease: Does Testing Material Matter?
Marília Sampaio, Natalie Argolo, Ailton Melo, Ana Caline Nóbrega
Dysphagia 2014 Jul;
PMID: 25001523 [PubMed - as supplied by publisher]


Parkinsonian syndrome in familial frontotemporal dementia.
Joanna Siuda, Shinsuke Fujioka, Zbigniew K Wszolek
Parkinsonism Relat Disord 2014 Jun;
PMID: 24998994 [PubMed - as supplied by publisher]


Computational Prediction of a Putative Binding Site on Drp1: Implications for Antiparkinsonian Therapy.
Hanumanthappa Pradeep, G Krishnamurthy Rajanikant
J Chem Inf Model 2014 Jul;
PMID: 24977305 [PubMed - as supplied by publisher]


Glucocerebrosidase mutations in Thai patients with Parkinson's disease.
Teeratorn Pulkes, Lulin Choubtum, Sermsiri Chitphuk, Ammarin Thakkinstian, Sunsanee Pongpakdee, Kongkiat Kulkantrakorn, Suchat Hanchaiphiboolkul, Somsak Tiamkao, Pairoj Boonkongchuen
Parkinsonism Relat Disord 2014 Jun;
PMID: 24997549 [PubMed - as supplied by publisher]


Sustained remission of Parkinson disease associated melanoma with immunotherapy.
David R Shprecher, Kenneth F Grossmann, Jonathan D Tward
Parkinsonism Relat Disord 2014 Jun;
PMID: 24997547 [PubMed - as supplied by publisher]


Off and on state assessment of swallowing function in Parkinson's disease.
Tobias Warnecke, Christina Hamacher, Stephan Oelenberg, Rainer Dziewas
Parkinsonism Relat Disord 2014 Jun;
PMID: 24997546 [PubMed - as supplied by publisher]


Plasma exosomal ?-synuclein is likely CNS-derived and increased in Parkinson's disease.
Min Shi, Changqin Liu, Travis J Cook, Kristin M Bullock, Yanchun Zhao, Carmen Ginghina, Yanfei Li, Patrick Aro, Romel Dator, Chunmei He, Michael J Hipp, Cyrus P Zabetian, Elaine R Peskind, Shu-Ching Hu, Joseph F Quinn, Douglas R Galasko, William A Banks, Jing Zhang
Acta Neuropathol 2014 Jul;
PMID: 24997849 [PubMed - as supplied by publisher]


Role of genomics in translational research for Parkinson's disease.
Kazunari Sekiyama, Yoshiki Takamatsu, Masaaki Waragai, Makoto Hashimoto
Biochem Biophys Res Commun 2014 Jun;
PMID: 24950403 [PubMed - as supplied by publisher]


Confirmation of the association between LRRK2 R1628P variant and susceptibility to Parkinson's disease in the Thai population.
Teeratorn Pulkes, Chutima Papsing, Ammarin Thakkinstian, Sunsanee Pongpakdee, Kongkiat Kulkantrakorn, Suchat Hanchaiphiboolkul, Somsak Tiamkao, Pairoj Boonkongchuen
Parkinsonism Relat Disord 2014 Jun;
PMID: 24997548 [PubMed - as supplied by publisher]


Parkinson Disease Treatment in Hospitals and Nursing Facilities: Avoiding Pitfalls.
J Eric Ahlskog
Mayo Clin Proc 2014 Jul; 89(7):997-1003
PMID: 24996235 [PubMed - as supplied by publisher]


Stage-dependent nigral neuronal loss in incidental Lewy body and Parkinson's disease.
Anke A Dijkstra, Pieter Voorn, Henk W Berendse, Henk J Groenewegen, , Annemieke J M Rozemuller, Wilma D J van de Berg
Mov Disord 2014 Jul;
PMID: 24996051 [PubMed - as supplied by publisher]


Deficits in motor performance after pedunculopontine lesions in rats - impairment depends on demands of task.
Duncan A A MacLaren, Joseph A Santini, Ashley L Russell, Tamara Markovic, Stewart D Clark
Eur J Neurosci 2014 Jul;
PMID: 24995993 [PubMed - as supplied by publisher]


The brainstem pathologies of Parkinson's disease and dementia with Lewy bodies.
Kay Seidel, Josefine Mahlke, Sonny Siswanto, Reijko Krüger, Helmut Heinsen, Georg Auburger, Mohamed Bouzrou, Lt Grinberg, Helmut Wicht, Horst-Werner Korf, Wilfred den Dunnen, Udo Rüb
Brain Pathol 2014 Jul;
PMID: 24995389 [PubMed - as supplied by publisher]


Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
Niccolň E Mencacci, Ioannis U Isaias, Martin M Reich, Christos Ganos, Vincent Plagnol, James M Polke, Jose Bras, Joshua Hersheson, Maria Stamelou, Alan M Pittman, Alastair J Noyce, Kin Y Mok, Thomas Opladen, Erdmute Kunstmann, Sybille Hodecker, Alexander Münchau, Jens Volkmann, Samuel Samnick, Katie Sidle, Tina Nanji, Mary G Sweeney, Henry Houlden, Amit Batla, Anna L Zecchinelli, Gianni Pezzoli, Giorgio Marotta, Andrew Lees, Paulo Alegria, Paul Krack, Florence Cormier-Dequaire, Suzanne Lesage, Alexis Brice, Peter Heutink, Thomas Gasser, Steven J Lubbe, Huw R Morris, Pille Taba, Sulev Koks, Elisa Majounie, J Raphael Gibbs, Andrew Singleton, John Hardy, Stephan Klebe, Kailash P Bhatia, Nicholas W Wood,
Brain 2014 Jul;
PMID: 24993959 [PubMed - as supplied by publisher]


Treatment effect of memantine on survival in dementia with Lewy bodies and Parkinson's disease with dementia: a prospective study.
Kajsa Stubendorff, Victoria Larsson, Clive Ballard, Lennart Minthon, Dag Aarsland, Elisabet Londos
BMJ Open 2014 ; 4(7):e005158
PMID: 24993765 [PubMed - as supplied by publisher]


Suicide prevention in neurology patients: evidence to guide practice.
DeJasna S Lewis, Kathryn Hoehn Anderson, Johanna Feuchtinger
J Neurosci Nurs 2014 Aug; 46(4):241-8
PMID: 24992150 [PubMed - as supplied by publisher]


A comprehensive profile of the sociodemographic, psychosocial and health characteristics of Ontario home care clients with dementia.
M Vu, D B Hogan, S B Patten, N Jetté, S E Bronskill, G Heckman, M J Kergoat, J P Hirdes, X Chen, M M Zehr, C J Maxwell
Chronic Dis Inj Can 2014 Jul; 34(2-3):132-44
PMID: 24991776 [PubMed - as supplied by publisher]


New treatment options for the management of restless leg syndrome.
Beatriz Elizabeth Carmona Toro
J Neurosci Nurs 2014 Aug; 46(4):227-32
PMID: 24992148 [PubMed - as supplied by publisher]


Salvianolic Acid B Attenuates Toxin-Induced Neuronal Damage via Nrf2-Dependent Glial Cells-Mediated Protective Activity in Parkinson's Disease Models.
Jie Zhou, Xiao-Dong Qu, Zhi-Yun Li, Wei-Ji, Qi Liu, Yi-Hui Ma, Jiao-Jiang He
PLoS One 2014 ; 9(7):e101668
PMID: 24991814 [PubMed - as supplied by publisher]


Titer and product affect the distribution of gene expression after intraputaminal convection-enhanced delivery.
Marina E Emborg, Samuel A Hurley, Valerie Joers, Do P M Tromp, Christine R Swanson, Sachiko Ohshima-Hosoyama, Viktorya Bondarenko, Kyle Cummisford, Marc Sonnemans, Stephan Hermening, Bas Blits, Andrew L Alexander
Stereotact Funct Neurosurg 2014 ; 92(3):182-94
PMID: 24943657 [PubMed - as supplied by publisher]


Diet-induced obesity accelerates the onset of terminal phenotypes in ?-synuclein transgenic mice.
Carola Rotermund, Felicia M Truckenmüller, Heinrich Schell, Philipp J Kahle
J Neurochem 2014 Jul;
PMID: 24995537 [PubMed - as supplied by publisher]


Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin.
R A Charan, B N Johnson, S Zaganelli, J D Nardozzi, M J LaVoie
Cell Death Dis 2014 ; 5:e1313
PMID: 24991765 [PubMed - as supplied by publisher]


Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease.
Laurie H Sanders, Jennifer McCoy, Xiaoping Hu, Pier G Mastroberardino, Bryan C Dickinson, Christopher J Chang, Charleen T Chu, Bennett Van Houten, J Timothy Greenamyre
Neurobiol Dis 2014 Jun;
PMID: 24981012 [PubMed - as supplied by publisher]


Glimepiride reduces CD14 expression and cytokine secretion from macrophages.
Victoria Ingham, Alun Williams, Clive Bate
J Neuroinflammation 2014 ; 11:115
PMID: 24952384 [PubMed - as supplied by publisher]


Expression analysis of genes of ubiquitin-proteasome protein degradation system in MPTP-induced mice models of early stages of Parkinson's disease.
E V Filatova, M I Shadrina, A Kh Alieva, A A Kolacheva, P A Slominsky, M V Ugrumov
Dokl Biochem Biophys 2014 May; 456(1):116-8
PMID: 24993970 [PubMed - as supplied by publisher]


Latest treatment options for Alzheimer's disease, Parkinson's disease dementia and dementia with Lewy bodies.
Martin Broadstock, Clive Ballard, Anne Corbett
Expert Opin Pharmacother 2014 Jul; :1-14
PMID: 24992196 [PubMed - as supplied by publisher]


Using the Montreal Cognitive Assessment Scale to screen for dementia in Chinese patients with Parkinson's Disease.
Ling Chen, Cuiyu Yu, Xiaosu Fu, Weiguo Liu, Ping Hua, Ning Zhang, Shenghan Kuo
Shanghai Arch Psychiatry 2013 Oct; 25(5):306-13
PMID: 24991170 [PubMed - as supplied by publisher]


Phase I/II randomized trial of aerobic exercise in Parkinson disease in a community setting.
Ergun Y Uc, Kevin C Doerschug, Vincent Magnotta, Jeffrey D Dawson, Teri R Thomsen, Joel N Kline, Matthew Rizzo, Sara R Newman, Sonya Mehta, Thomas J Grabowski, Joel Bruss, Derek R Blanchette, Steven W Anderson, Michelle W Voss, Arthur F Kramer, Warren G Darling
Neurology 2014 Jul;
PMID: 24991037 [PubMed - as supplied by publisher]


TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Gernot Kleinberger, Yoshinori Yamanishi, Marc Suárez-Calvet, Eva Czirr, Ebba Lohmann, Elise Cuyvers, Hanne Struyfs, Nadine Pettkus, Andrea Wenninger-Weinzierl, Fargol Mazaheri, Sabina Tahirovic, Alberto Lleó, Daniel Alcolea, Juan Fortea, Michael Willem, Sven Lammich, José L Molinuevo, Raquel Sánchez-Valle, Anna Antonell, Alfredo Ramirez, Michael T Heneka, Kristel Sleegers, Julie van der Zee, Jean-Jacques Martin, Sebastiaan Engelborghs, Asli Demirtas-Tatlidede, Henrik Zetterberg, Christine Van Broeckhoven, Hakan Gurvit, Tony Wyss-Coray, John Hardy, Marco Colonna, Christian Haass
Sci Transl Med 2014 Jul; 6(243):243ra86
PMID: 24990881 [PubMed - as supplied by publisher]


The relevance of dopaminergic level in nocturnal disability in Parkinson's disease: implications of continuous dopaminergic stimulation at night to treat the symptoms.
Fabrizio Stocchi, Paola Stirpe
J Neural Transm 2014 Jul;
PMID: 24990308 [PubMed - as supplied by publisher]


The impact of high intensity physical training on motor and non-motor symptoms in patients with Parkinson's disease (PIP): A preliminary study.
Bo M Morberg, Joakim Jensen, Matthias Bode, Lene Wermuth
NeuroRehabilitation 2014 Jul;
PMID: 24990028 [PubMed - as supplied by publisher]


Effectiveness of a novel community exercise transition program for people with moderate to severe neurological disabilities.
Michelle Ploughman, Jennifer Shears, Chelsea Harris BKin, Stephen H Hogan, Olivia Drodge, Sherry Squires, Jason McCarthy
NeuroRehabilitation 2014 Jul;
PMID: 24990000 [PubMed - as supplied by publisher]


Therapeutic Development Paths for Cognitive Impairment in Parkinson's Disease: Report of a Regulatory Roundtable.
Jamie Eberling, Lona Vincent, Jennifer G Goldman, Daniel Weintraub, Jaime Kulisevsky, Connie Marras, Glenn Stebbins, Karl Kieburtz
J Parkinsons Dis 2014 Jul;
PMID: 24989876 [PubMed - as supplied by publisher]


Update on SPECT and PET in parkinsonism - part 2: biomarker imaging of cognitive impairment in Lewy-body diseases.
Philipp T Meyer, Lars Frings, Sabine Hellwig
Curr Opin Neurol 2014 Aug; 27(4):398-404
PMID: 24978635 [PubMed - as supplied by publisher]


Efficient Reprogramming of Mouse Fibroblasts to Neuronal Cells including Dopaminergic Neurons.
Seung-Ick Oh, Hang-Soo Park, Insik Hwang, Han-Kyul Park, Kyung-Ah Choi, Hyesun Jeong, Suhng Wook Kim, Sunghoi Hong
ScientificWorldJournal 2014 ; 2014:957548
PMID: 24991651 [PubMed - as supplied by publisher]


Cell-based assays for Parkinson's disease using differentiated human LUHMES cells.
Xiao-Min Zhang, Ming Yin, Min-Hua Zhang
Acta Pharmacol Sin 2014 Jul; 35(7):945-56
PMID: 24989254 [PubMed - as supplied by publisher]


Treatment of advanced Parkinson's disease.
Juan C Giugni, Michael S Okun
Curr Opin Neurol 2014 Aug; 27(4):450-60
PMID: 24978634 [PubMed - as supplied by publisher]


Functional anatomy of subthalamic nucleus stimulation in Parkinson disease.
Sarah A Eisenstein, Jonathan M Koller, Kathleen D Black, Meghan C Campbell, Heather M Lugar, Mwiza Ushe, Samer D Tabbal, Morvarid Karimi, Tamara Hershey, Joel S Perlmutter, Kevin J Black
Ann Neurol 2014 Jun;
PMID: 24953991 [PubMed - as supplied by publisher]


Treatment of early Parkinson's disease.
Rajesh Pahwa, Kelly E Lyons
Curr Opin Neurol 2014 Aug; 27(4):442-9
PMID: 24950010 [PubMed - as supplied by publisher]


Designer receptors: therapeutic adjuncts to cell replacement therapy in Parkinson's disease.
Elena M Vazey, Gary Aston-Jones
J Clin Invest 2014 Jul; 124(7):2858-60
PMID: 24937425 [PubMed - as supplied by publisher]


Sleep Disorders in Parkinsonian Macaques: Effects of l-Dopa Treatment and Pedunculopontine Nucleus Lesion.
Hayat Belaid, Joëlle Adrien, Elodie Laffrat, Dominique Tandé, Carine Karachi, David Grabli, Isabelle Arnulf, Stewart D Clark, Xavier Drouot, Etienne C Hirsch, Chantal François
J Neurosci 2014 Jul; 34(27):9124-33
PMID: 24990932 [PubMed - as supplied by publisher]


A model in which heat shock protein 90 targets protein-folding clefts: Rationale for a new approach to neuroprotective treatment of protein folding diseases.
William B Pratt, Yoshihiro Morishima, Jason E Gestwicki, Andrew P Lieberman, Yoichi Osawa
Exp Biol Med (Maywood) 2014 Jul;
PMID: 24990484 [PubMed - as supplied by publisher]


Defective Autophagy in Parkinson's Disease: Lessons from Genetics.
H Zhang, C Duan, H Yang
Mol Neurobiol 2014 Jul;
PMID: 24990317 [PubMed - as supplied by publisher]


Elevation of striatal urate in experimental models of Parkinson's disease: a compensatory mechanism triggered by dopaminergic nigrostriatal degeneration?
Maria Antonietta De Luca, Omar Cauli, Micaela Morelli, Nicola Simola
J Neurochem 2014 Jul;
PMID: 24989117 [PubMed - as supplied by publisher]


SREBF1 links lipogenesis to mitophagy and sporadic Parkinson disease.
Rachael M Ivatt, Alexander J Whitworth
Autophagy 2014 Jun; 10(8)
PMID: 24991824 [PubMed - as supplied by publisher]


Genetic dissection reveals that Akt is the critical kinase downstream of LRRK2 to phosphorylate and inhibit FOXO1, and promotes neuron survival.
Chia-Lung Chuang, Yu-Ning Lu, Hung-Cheng Wang, Hui-Yun Chang
Hum Mol Genet 2014 Jun;
PMID: 24916379 [PubMed - as supplied by publisher]


Levels of cerebrospinal fluid ?-synuclein oligomers are increased in Parkinson's disease with dementia and dementia with Lewy bodies compared to Alzheimer's disease.
Oskar Hansson, Sara Hall, Annika Ohrfelt, Henrik Zetterberg, Kaj Blennow, Lennart Minthon, Katarina Nägga, Elisabet Londos, Shiji Varghese, Nour K Majbour, Abdulmonem Al-Hayani, Omar Ma El-Agnaf
Alzheimers Res Ther 2014 ; 6(3):25
PMID: 24987465 [PubMed - as supplied by publisher]


Screening for impaired cognitive domains in a large Parkinson's disease population and its application to the diagnostic procedure for Parkinson's disease dementia.
Kouichi Ohta, Kazushi Takahashi, Jun Gotoh, Keiji Yamaguchi, Morinobu Seki, Yoshihiro Nihei, Satoko Iwasawa, Norihiro Suzuki,
Dement Geriatr Cogn Dis Extra 2014 May; 4(2):147-59
PMID: 24987404 [PubMed - as supplied by publisher]


Neuronal intranuclear inclusion disease presenting with resting tremor.
Naoyuki Kitagawa, Jun Sone, Gen Sobue, Masahiko Kuroda, Michio Sakurai
Case Rep Neurol 2014 May; 6(2):176-80
PMID: 24987362 [PubMed - as supplied by publisher]


Individual and joint prevalence of three nonmotor symptoms of PD in the US general population.
Honglei Chen, Xuemei Huang, Xuguang Guo, Shyamal Peddada
Mov Disord 2014 Jul;
PMID: 24985078 [PubMed - as supplied by publisher]


The default mode network is disrupted in parkinson's disease with visual hallucinations.
Nailin Yao, Richard Shek-Kwan Chang, Charlton Cheung, Shirley Pang, Kui Kai Lau, John Suckling, James Rowe, Kevin Yu, Henry Ka-Fung Mak, Siew-Eng Chua, Shu Leong Ho, Grainne M McAlonan
Hum Brain Mapp 2014 Jul;
PMID: 24985056 [PubMed - as supplied by publisher]


Bladder function in patients with dystonia undergoing deep brain stimulation.
Livio Mordasini, Thomas M Kessler, Bernhard Kiss, Michael Schüpbach, Claudio Pollo, Alain Kaelin-Lang
Parkinsonism Relat Disord 2014 Jun;
PMID: 24984838 [PubMed - as supplied by publisher]


Perspectives on Parkinson Disease Care in Dutch Nursing Homes.
Anouke van Rumund, Nico Weerkamp, Gerrit Tissingh, Sytse U Zuidema, Raymond T Koopmans, Marten Munneke, Petra J E Poels, Bastiaan R Bloem
J Am Med Dir Assoc 2014 Jun;
PMID: 24984788 [PubMed - as supplied by publisher]


Aerobic exercise for Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials.
Hai-Feng Shu, Tao Yang, Si-Xun Yu, Hai-Dong Huang, Ling-Li Jiang, Jian-Wen Gu, Yong-Qin Kuang
PLoS One 2014 ; 9(7):e100503
PMID: 24983753 [PubMed - as supplied by publisher]


Creatine for Parkinson's disease.
Yousheng Xiao, Man Luo, Hongye Luo, Jin Wang
Cochrane Database Syst Rev 2014 ; 6:CD009646
PMID: 24934384 [PubMed - as supplied by publisher]


Upstream deregulation of calcium signaling in Parkinson's disease.
Pilar Rivero-Ríos, Patricia Gómez-Suaga, Elena Fdez, Sabine Hilfiker
Front Mol Neurosci 2014 ; 7:53
PMID: 24987329 [PubMed - as supplied by publisher]


Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of ?-synuclein.
Nicola J Rutherford, Brenda D Moore, Todd E Golde, Benoit I Giasson
J Neurochem 2014 Jul;
PMID: 24984882 [PubMed - as supplied by publisher]


Gait speed in Parkinson disease correlates with cholinergic degeneration.
William M Landau, Nicolaas I Bohnen, Vikas Kotagal, Roger Albin, Martijn Muller
Neurology 2014 Jul; 83(1):102-3
PMID: 24982040 [PubMed - as supplied by publisher]


Improvement in dystonic camptocormia following botulinum toxin injection to the external oblique muscle.
Subhashie Wijemanne, Joohi Jimenez-Shahed
Parkinsonism Relat Disord 2014 Jun;
PMID: 24981917 [PubMed - as supplied by publisher]


Contributions of mild parkinsonian signs to gait performance in the elderly.
Gilles Allali, Joe Verghese, Jeannette R Mahoney
Age (Dordr) 2014 Aug; 36(4):9678
PMID: 24981115 [PubMed - as supplied by publisher]


Association of Parkinson's disease with altered serum levels of lead and transition metals among South Indian subjects.
Yalavarthy Prameela Devi, Shaik Mohammad Naushad, Rukmini Mridula, Rupam Borgohain, Kumar Kutala Vijay
Indian J Biochem Biophys 2014 Apr; 51(2):121-6
PMID: 24980015 [PubMed - as supplied by publisher]


The role of alpha-synuclein in Parkinson's disease].
Ildiko Miklya, Noemi Pencz, Florencia Hafenscher, Patricia Goltl
Neuropsychopharmacol Hung 2014 Jun; 16(2):77-84
PMID: 24978050 [PubMed - as supplied by publisher]


The role of parkin in Parkinson's disease].
Ildiko Miklya, Patricia Goltl, Florencia Hafenscher, Noemi Pencz
Neuropsychopharmacol Hung 2014 Jun; 16(2):67-76
PMID: 24978049 [PubMed - as supplied by publisher]


Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson's disease.
Naoto Kadoguchi, Shinji Okabe, Yukio Yamamura, Misaki Shono, Tatsuya Fukano, Akie Tanabe, Hironori Yokoyama, Jiro Kasahara
BMC Neurosci 2014 ; 15:79
PMID: 24965042 [PubMed - as supplied by publisher]


Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats.
Vez Repunte-Canonigo, Celine Lefebvre, Olivier George, Tomoya Kawamura, Marisela Morales, George Koob, Andrea Califano, Eliezer Masliah, Pietro Paolo Sanna
Mol Neurodegener 2014 Jul; 9(1):26
PMID: 24980976 [PubMed - as supplied by publisher]


Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation.
Ian J McGough, Florian Steinberg, Da Jia, Peter A Barbuti, Kirsty J McMillan, Kate J Heesom, Maeve A Caldwell, Daniel D Billadeau, Michael K Rosen, Peter J Cullen
Curr Biol 2014 Jun;
PMID: 24980502 [PubMed - as supplied by publisher]


Suprathreshold odor intensity perception in early-stage Parkinson's disease.
Richard L Doty, Evan Beals, Allen Osman, Jacob Dubroff, Inna Chung, Fidias E Leon-Sarmiento, Howard Hurtig, Gui-Shuang Ying
Mov Disord 2014 Jun;
PMID: 24976213 [PubMed - as supplied by publisher]


MR-Guided Focused Ultrasound: A New Generation Treatment of Parkinson's Disease, Essential Tremor and Neuropathic Pain.
Pawel Piotr Dobrakowski, Agnieszka Kamila Machowska-Majchrzak, Beata Labuz-Roszak, Krzysztof Grzegorz Majchrzak, Ewa Kluczewska, Krystyna Barbara Pierzcha?a
Interv Neuroradiol 2014 Jun; 20(3):275-82
PMID: 24976088 [PubMed - as supplied by publisher]


Low clinical diagnostic accuracy of early vs advanced Parkinson disease: Clinicopathologic study.
Charles H Adler, Thomas G Beach, Joseph G Hentz, Holly A Shill, John N Caviness, Erika Driver-Dunckley, Marwan N Sabbagh, Lucia I Sue, Sandra A Jacobson, Christine M Belden, Brittany N Dugger
Neurology 2014 Jun;
PMID: 24975862 [PubMed - as supplied by publisher]


L-DOPA-induced dyskinesia in a rat model of Parkinson's disease is associated with the fluctuational release of norepinephrine in the sensorimotor striatum.
Yong Wang, Hui Sheng Wang, Tao Wang, Chen Huang, Jian Liu
J Neurosci Res 2014 Jun;
PMID: 24975553 [PubMed - as supplied by publisher]


Is pineal melatonin released in the third ventricle in humans? A study in movement disorders.
J Leston, C Harthé, C Mottolese, P Mertens, M Sindou, B Claustrat
Neurochirurgie 2014 Jun;
PMID: 24975205 [PubMed - as supplied by publisher]


Coordinated reset neuromodulation for Parkinson's disease: Proof-of-concept study.
Ilya Adamchic, Christian Hauptmann, Utako Brigit Barnikol, Norbert Pawelczyk, Oleksandr Popovych, Thomas Theo Barnikol, Alexander Silchenko, Jens Volkmann, Günter Deuschl, Wassilios G Meissner, Mohammad Maarouf, Volker Sturm, Hans-Joachim Freund, Peter Alexander Tass
Mov Disord 2014 Jun;
PMID: 24976001 [PubMed - as supplied by publisher]


Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease.
Kuldip D Dave, Shehan De Silva, Niketa P Sheth, Sylvie Ramboz, Melissa J Beck, Changyu Quang, Robert C Switzer, Syed Ahmad, Susan M Sunkin, Dan Walker, Xiaoxia Cui, Daniel A Fisher, Aaron M McCoy, Kevin Gamber, Xiaodong Ding, Matthew S Goldberg, Stanley A Benkovic, Meredith Haupt, Marco A S Baptista, Brian K Fiske, Todd B Sherer, Mark A Frasier
Neurobiol Dis 2014 Jun;
PMID: 24969022 [PubMed - as supplied by publisher]


Parkin-mediated ubiquitination of mutant glucocerebrosidase leads to competition with its substrates PARIS and ARTS.
Inna Bendikov-Bar, Debora Rapaport, Sarit Larisch, Mia Horowitz
Orphanet J Rare Dis 2014 ; 9:86
PMID: 24935484 [PubMed - as supplied by publisher]


Identification of a Japanese family with LRRK2 p.R1441G-related Parkinson's disease.
Taku Hatano, Manabu Funayama, Shin-Ichiro Kubo, Ignacio F Mata, Yutaka Oji, Akio Mori, Cyrus P Zabetian, Sarah M Waldherr, Hiroyo Yoshino, Genko Oyama, Yasushi Shimo, Ken-Ichi Fujimoto, Hirokazu Oshima, Yasuto Kunii, Hirooki Yabe, Yoshikuni Mizuno, Nobutaka Hattori
Neurobiol Aging 2014 Jun;
PMID: 24973808 [PubMed - as supplied by publisher]


Causes and Consequences of MicroRNA Dysregulation in Neurodegenerative Diseases.
Lin Tan, Jin-Tai Yu, Lan Tan
Mol Neurobiol 2014 Jun;
PMID: 24973986 [PubMed - as supplied by publisher]


Association between 5-HTTLPR polymorphism and Parkinson's disease: a meta analysis.
Lianbo Gao, Honghua Gao
Mol Biol Rep 2014 Jun;
PMID: 24972569 [PubMed - as supplied by publisher]


The monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model.
Diana Fernández-Suárez, Marta Celorrio, José Ignacio Riezu-Boj, Ana Ugarte, Rodrigo Pacheco, Hugo González, Julen Oyarzabal, Cecilia J Hillard, Rafael Franco, María S Aymerich
Neurobiol Aging 2014 May;
PMID: 24973119 [PubMed - as supplied by publisher]


Brain morphometry and the neurobiology of levodopa-induced dyskinesias: current knowledge and future potential for translational pre-clinical neuroimaging studies.
Clare J Finlay, Susan Duty, Anthony C Vernon
Front Neurol 2014 ; 5:95
PMID: 24971074 [PubMed - as supplied by publisher]


Amantadine and cognitive flexibility: decision making in Parkinson's patients with severe pathological gambling and other impulse control disorders.
Nicoletta Cera, Stefania Bifolchetti, Giovanni Martinotti, Francesco Gambi, Gianna Sepede, Marco Onofrj, Massimo Di Giannantonio, Astrid Thomas
Neuropsychiatr Dis Treat 2014 ; 10:1093-101
PMID: 24971012 [PubMed - as supplied by publisher]


AACE/ACE Disease State Clinical Review: Dopamine Agonists for Hyperprolactinemia and the Risk of Cardiac Valve Disease.
Susan L Samson, Shereen Ezzat
Endocr Pract 2014 Jun; 20(6):608-16
PMID: 24969114 [PubMed - as supplied by publisher]


Observations on sleep-disordered breathing in idiopathic Parkinson's disease.
Philipp O Valko, Sabrina Hauser, Michael Sommerauer, Esther Werth, Christian R Baumann
PLoS One 2014 ; 9(6):e100828
PMID: 24968233 [PubMed - as supplied by publisher]


A rapid and simple method for the determination of 3,4-dihydroxyphenylacetic acid, norepinephrine, dopamine, and serotonin in mouse brain homogenate by HPLC with fluorimetric detection.
Giuseppe Egidio De Benedetto, Daniela Fico, Antonio Pennetta, Cosimino Malitesta, Giuseppe Nicolardi, Dario Domenico Lofrumento, Francesco De Nuccio, Velia La Pesa
J Pharm Biomed Anal 2014 Jun; 98C:266-270
PMID: 24971521 [PubMed - as supplied by publisher]


Transglutaminase 2 exacerbates ?-synuclein toxicity in mice and yeast.
Hilary Grosso, Jong-Min Woo, Kang-Woo Lee, Joo-Young Im, Eliezer Masliah, Eunsung Junn, M Maral Mouradian
FASEB J 2014 Jun;
PMID: 24970392 [PubMed - as supplied by publisher]


Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P immunoreactivity in Huntington's disease: a preliminary investigation in the postmortem human brain.
Balázs Gulyás, Judit Sovago, Baltazar Gomez-Mancilla, Zhisheng Jia, Csaba Szigeti, Károly Gulya, Martin Schumacher, Ralph Paul Maguire, Fabrizio Gasparini, Christer Halldin
Brain Struct Funct 2014 Jun;
PMID: 24969128 [PubMed - as supplied by publisher]


The role of dopamine in huntington's disease.
Carlos Cepeda, Kerry P S Murphy, Martin Parent, Michael S Levine
Prog Brain Res 2014 ; 211:235-54
PMID: 24968783 [PubMed - as supplied by publisher]


Prospective Memory Performance of Patients with Parkinson's Disease Depends on Shifting Aptitude: Evidence from Cognitive Rehabilitation.
Alberto Costa, Antonella Peppe, Francesca Serafini, Silvia Zabberoni, Francesco Barban, Carlo Caltagirone, Giovanni Augusto Carlesimo
J Int Neuropsychol Soc 2014 Jun; :1-10
PMID: 24967725 [PubMed - as supplied by publisher]


Deep brain stimulation in psychiatry.
Milana Pozni? Jesi?, Olga Zivanovi?', Igor Nikoli?, Sasa Radovanovi?, Branislav Saki?, Aleksandar Jesi?
Med Pregl 2014 Jan-Feb; 67(1-2):28-32
PMID: 24964565 [PubMed - as supplied by publisher]


Progressive supranuclear palsy.
Lawrence I Golbe
Semin Neurol 2014 Apr; 34(2):151-9
PMID: 24963674 [PubMed - as supplied by publisher]


The neurogenetics of atypical parkinsonian disorders.
Brent L Fogel, Mary C Clark, Daniel H Geschwind
Semin Neurol 2014 Apr; 34(2):217-24
PMID: 24963681 [PubMed - as supplied by publisher]


Neuropathologic changes of multiple system atrophy and diffuse lewy body disease.
Etty Paola Cortes Ramirez, Jean Paul G Vonsattel
Semin Neurol 2014 Apr; 34(2):210-6
PMID: 24963680 [PubMed - as supplied by publisher]


Dementia with lewy bodies.
Mary Catherine Mayo, Yvette Bordelon
Semin Neurol 2014 Apr; 34(2):182-8
PMID: 24963677 [PubMed - as supplied by publisher]


Naringin: a protector of the nigrostriatal dopaminergic projection.
Un Ju Jung, Eunju Leem, Sang Ryong Kim
Exp Neurobiol 2014 Jun; 23(2):124-9
PMID: 24963276 [PubMed - as supplied by publisher]


High-throughput Functional Screening using a Homemade Dual-glow Luciferase Assay.
Jessica M Baker, Frederick M Boyce
J Vis Exp 2014 ; (88)
PMID: 24962249 [PubMed - as supplied by publisher]


Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease.
Takahiro Fujimaki, Shinji Saiki, Etsu Tashiro, Daisuke Yamada, Mitsuhiro Kitagawa, Nobutaka Hattori, Masaya Imoto
PLoS One 2014 ; 9(6):e100395
PMID: 24960051 [PubMed - as supplied by publisher]


Tissue- and cell-specific mitochondrial defect in parkin-deficient mice.
Maria Damiano, Clément A Gautier, Anne-Laure Bulteau, Rosa Ferrando-Miguel, Caroline Gouarne, Marc Giraudon Paoli, Rebecca Pruss, Françoise Auchčre, Caroline L'Hermitte-Stead, Frédéric Bouillaud, Alexis Brice, Olga Corti, Anne Lombčs
PLoS One 2014 ; 9(6):e99898
PMID: 24959870 [PubMed - as supplied by publisher]


Nrf2 Signaling Contributes to the Neuroprotective Effects of Urate against 6-OHDA Toxicity.
Ning Zhang, Hai-Yang Shu, Tingting Huang, Qi-Lin Zhang, Da Li, Guan-Qun Zhang, Xiao-Yan Peng, Chun-Feng Liu, Wei-Feng Luo, Li-Fang Hu
PLoS One 2014 ; 9(6):e100286
PMID: 24959672 [PubMed - as supplied by publisher]


N-Terminal Truncated UCH-L1 Prevents Parkinson's Disease Associated Damage.
Hee-Jung Kim, Hyun Jung Kim, Jae-Eun Jeong, Jeong Yeob Baek, Jaeho Jeong, Sun Kim, Young-Mee Kim, Youhwa Kim, Jin Han Nam, Sue Hee Huh, Jawon Seo, Byung Kwan Jin, Kong-Joo Lee
PLoS One 2014 ; 9(6):e99654
PMID: 24959670 [PubMed - as supplied by publisher]


Suppression of miR-155 Expression in IFN-?-Treated Astrocytes and Microglia by DJ-1: A Possible Mechanism for Maintaining SOCS1 Expression.
Jong-Hyeon Kim, Ilo Jou, Eun-Hye Joe
Exp Neurobiol 2014 Jun; 23(2):148-54
PMID: 24963279 [PubMed - as supplied by publisher]


Bioinformatics analysis raises candidate genes in blood for early screening of Parkinson's disease.
Yi Zhang, Li Yao, Wei Liu, Wei Li, Chan Tian, Zhao Yang Wang, Di Liu
Biomed Environ Sci 2014 Jun; 27(6):462-5
PMID: 24961856 [PubMed - as supplied by publisher]


Abrogation of ?-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats.
Joăo P L Daher, Laura A Volpicelli-Daley, Jonathan P Blackburn, Mark S Moehle, Andrew B West
Proc Natl Acad Sci U S A 2014 Jun; 111(25):9289-94
PMID: 24927544 [PubMed - as supplied by publisher]


Simultaneous improvement of tics and parkinsonism after pallidal DBS.
Neepa Patel, Joohi Jimenez-Shahed
Parkinsonism Relat Disord 2014 Jun;
PMID: 24957594 [PubMed - as supplied by publisher]


Identification of circulating microRNAs for the differential diagnosis of Parkinson's disease and Multiple System Atrophy.
Annamaria Vallelunga, Marco Ragusa, Stefania Di Mauro, Tommaso Iannitti, Manuela Pilleri, Roberta Biundo, Luca Weis, Cinzia Di Pietro, Angela De Iuliis, Alessandra Nicoletti, Mario Zappia, Michele Purrello, Angelo Antonini
Front Cell Neurosci 2014 ; 8:156
PMID: 24959119 [PubMed - as supplied by publisher]


Heterogeneity of Leucine-Rich Repeat Kinase 2 Mutations: Genetics, Mechanisms and Therapeutic Implications.
Iakov N Rudenko, Mark R Cookson
Neurotherapeutics 2014 Jun;
PMID: 24957201 [PubMed - as supplied by publisher]


Large-Scale East-Asian eQTL Mapping Reveals Novel Candidate Genes for LD Mapping and the Genomic Landscape of Transcriptional Effects of Sequence Variants.
Maiko Narahara, Koichiro Higasa, Seiji Nakamura, Yasuharu Tabara, Takahisa Kawaguchi, Miho Ishii, Kenichi Matsubara, Fumihiko Matsuda, Ryo Yamada
PLoS One 2014 ; 9(6):e100924
PMID: 24956270 [PubMed - as supplied by publisher]


Automated Acoustic Analysis in Detection of Spontaneous Swallows in Parkinson's Disease.
Marzieh Golabbakhsh, Ali Rajaei, Mahmoud Derakhshan, Saeed Sadri, Masoud Taheri, Peyman Adibi
Dysphagia 2014 Jun;
PMID: 24958599 [PubMed - as supplied by publisher]


Functional imaging of physiological and pathological speech production].
C A Kell
Nervenarzt 2014 Jun; 85(6):701-7
PMID: 24832012 [PubMed - as supplied by publisher]


Metabolic Syndrome: An Important Risk Factor for Parkinson's Disease.
Pei Zhang, Bo Tian
Oxid Med Cell Longev 2014 ; 2014:729194
PMID: 24955210 [PubMed - as supplied by publisher]


The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases.
Petr Dusek, Per M Roos, Tomasz Litwin, Susanne A Schneider, Trond Peder Flaten, Jan Aaseth
J Trace Elem Med Biol 2014 Jun;
PMID: 24954801 [PubMed - as supplied by publisher]


Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives.
Anthony H V Schapira, C Warren Olanow, J Timothy Greenamyre, Erwan Bezard
Lancet 2014 Jun;
PMID: 24954676 [PubMed - as supplied by publisher]


Role of zinc and copper ions in the pathogenetic mechanisms of Alzheimer's and Parkinson's diseases.
E V Stelmashook, N K Isaev, E E Genrikhs, G A Amelkina, L G Khaspekov, V G Skrebitsky, S N Illarioshkin
Biochemistry (Mosc) 2014 May; 79(5):391-6
PMID: 24954589 [PubMed - as supplied by publisher]


Depression and Synaptic Zinc Regulation in Alzheimer Disease, Dementia with Lewy Bodies, and Parkinson Disease Dementia.
David R Whitfield, Julie Vallortigara, Amani Alghamdi, Tibor Hortobágyi, Clive Ballard, Alan J Thomas, John T O'Brien, Dag Aarsland, Paul T Francis
Am J Geriatr Psychiatry 2014 May;
PMID: 24953873 [PubMed - as supplied by publisher]


A single pathway targets several health challenges of the elderly.
Ben A Bahr
Rejuvenation Res 2014 Jun;
PMID: 24953230 [PubMed - as supplied by publisher]


Increasing the Coding Potential of Genomes Through Alternative Splicing: The Case of PARK2 Gene.
Valentina La Cognata, Rosario Iemmolo, Velia D'Agata, Soraya Scuderi, Filippo Drago, Mario Zappia, Sebastiano Cavallaro
Curr Genomics 2014 Jun; 15(3):203-16
PMID: 24955028 [PubMed - as supplied by publisher]


Subthalamic deep brain stimulation: clinical and neuropsychological outcomes in mild cognitive impaired parkinsonian patients.
Aristide Merola, Laura Rizzi, Carlo Alberto Artusi, Maurizio Zibetti, Mario Giorgio Rizzone, Alberto Romagnolo, Andrea Bernardini, Michele Lanotte, Leonardo Lopiano
J Neurol 2014 Jun;
PMID: 24952619 [PubMed - as supplied by publisher]


Characterizing Motor and Cognitive Effects Associated with Deep Brain Stimulation in the GPi of Hemi-Parkinsonian Rats.
Samantha Summerson, Behnaam Aazhang, Caleb Kemere
IEEE Trans Neural Syst Rehabil Eng 2014 Jun;
PMID: 24951705 [PubMed - as supplied by publisher]


Use of metabotropic glutamate 5-receptor antagonists for treatment of levodopa-induced dyskinesias.
Olivier Rascol, Susan Fox, Fabrizio Gasparini, Christopher Kenney, Thérčse Di Paolo, Baltazar Gomez-Mancilla
Parkinsonism Relat Disord 2014 May;
PMID: 24951359 [PubMed - as supplied by publisher]


Carvedilol Attenuates 6-Hydroxydopamine-Induced Cell Death in PC12 Cells: Involvement of Akt and Nrf2/ARE Pathways.
Lan Wang, Rikang Wang, Minghua Jin, Yingjuan Huang, Anmin Liu, Jian Qin, Meihui Chen, Shijun Wen, Rongbiao Pi, Wei Shen
Neurochem Res 2014 Jun;
PMID: 24952068 [PubMed - as supplied by publisher]


The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease.
Ilona Joniec-Maciejak, Agnieszka Ciesielska, Adriana Wawer, Anna Sznejder-Pacho?ek, Joanna Schwenkgrub, Agnieszka Cudna, Piotr Hadaczek, Kristof S Bankiewicz, Anna Cz?onkowska, Andrzej Cz?onkowski
Pharmacol Rep 2014 Aug; 66(4):660-9
PMID: 24948069 [PubMed - as supplied by publisher]


Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways.
Lauran Reyniers, Maria Grazia Del Giudice, Laura Civiero, Elisa Belluzzi, Evy Lobbestael, Alexandra Beilina, Giorgio Arrigoni, Rita Derua, Etienne Waelkens, Yan Li, Claudia Crosio, Ciro Iaccarino, Mark R Cookson, Veerle Baekelandt, Elisa Greggio, Jean-Marc Taymans
J Neurochem 2014 Jun;
PMID: 24947832 [PubMed - as supplied by publisher]


Dopaminergic-like neurons derived from oral mucosa stem cells by developmental cues improve symptoms in the hemi-parkinsonian rat model.
Javier Ganz, Ina Arie, Sigal Buch, Tali Ben Zur, Yael Barhum, Sammy Pour, Shareef Araidy, Sandu Pitaru, Daniel Offen
PLoS One 2014 ; 9(6):e100445
PMID: 24945922 [PubMed - as supplied by publisher]


Edaravone Protects Neurons in the Rat Substantia Nigra Against 6-Hydroxydopamine-Induced Oxidative Stress Damage.
Xiqi Liu, Rushing Shao, Meng Li, Guofeng Yang
Cell Biochem Biophys 2014 Jun;
PMID: 24948472 [PubMed - as supplied by publisher]


Statins - Are they anticonvulsant?
Monika Banach, Stanis?aw J Czuczwar, Kinga K Borowicz
Pharmacol Rep 2014 Aug; 66(4):521-528
PMID: 24948050 [PubMed - as supplied by publisher]


The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE).
Jengmin Kang, Kwang Chul Chung
Cell Mol Life Sci 2014 Jun;
PMID: 24947323 [PubMed - as supplied by publisher]


Safety Analysis of 10 Clinical Trials and for 13 Years After First Approval of Ioflupane 123I Injection (DaTscan).
Donald G Grosset, Klaus Tatsch, Wolfgang H Oertel, Eduardo Tolosa, Nin Bajaj, Andreas Kupsch, John T O'Brien, John Seibyl, Zuzana Walker, Paul Sherwin, Chris Chen, Igor D Grachev
J Nucl Med 2014 Jun;
PMID: 24947061 [PubMed - as supplied by publisher]


DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis.
Jun Ma, Rong Wu, Qiang Zhang, Junbing Wu, Jizhong Lou, Zheng Zheng, Jian-Qing Ding, Zengqiang Yuan
Biochem J 2014 Jun;
PMID: 24947010 [PubMed - as supplied by publisher]


Cognitive Fluctuations as a Challenge for the Assessment of Decision-Making Capacity in Patients With Dementia.
Manuel Trachsel, Helena Hermann, Nikola Biller-Andorno
Am J Alzheimers Dis Other Demen 2014 Jun;
PMID: 24946784 [PubMed - as supplied by publisher]


Inhibition of Neuroinflammation and Mitochondrial Dysfunctions by Carbenoxolone in the Rotenone Model of Parkinson's Disease.
Poonam Thakur, Bimla Nehru
Mol Neurobiol 2014 Jun;
PMID: 24946750 [PubMed - as supplied by publisher]


Phosphorylated ubiquitin: a new shade of PINK1 in Parkin activation.
Véronique Sauvé, Kalle Gehring
Cell Res 2014 Jun;
PMID: 24946738 [PubMed - as supplied by publisher]


Role of vitamin D in the physiopathology of neurodegenerative diseases].
Pascal Millet, Véréna Landel, Isabelle Virard, Maria Morello, François Féron
Biol Aujourdhui 2014 ; 208(1):77-88
PMID: 24948021 [PubMed - as supplied by publisher]


Cinnamon Treatment Upregulates Neuroprotective Proteins Parkin and DJ-1 and Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease.
Saurabh Khasnavis, Kalipada Pahan
J Neuroimmune Pharmacol 2014 Jun;
PMID: 24946862 [PubMed - as supplied by publisher]


Leucine-rich repeat kinase 2 inhibitors: a review of recent patents (2011 - 2013).
Raghava R Kethiri, Rajagopal Bakthavatchalam
Expert Opin Ther Pat 2014 Jul; 24(7):745-57
PMID: 24918198 [PubMed - as supplied by publisher]


Novel orthogonal liquid chromatography methods to dose neurotransmitters involved in Parkinson's disease.
Roccaldo Sardella, Stefania Scorzoni, Carmela Conte, Antonella Lisanti, Federica Ianni, Benedetto Natalini
J Pharm Biomed Anal 2014 May; 98C:253-259
PMID: 24946149 [PubMed - as supplied by publisher]


Lesion of the dopaminergic nigrostriatal pathway induces trigeminal dynamic mechanical allodynia.
Wisam Dieb, Omar Ouachikh, Franck Durif, Aziz Hafidi
Brain Behav 2014 May; 4(3):368-80
PMID: 24944866 [PubMed - as supplied by publisher]


Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial.
Horacio Kaufmann, Roy Freeman, Italo Biaggioni, Phillip Low, Simon Pedder, L Arthur Hewitt, Joe Mauney, Michael Feirtag, Christopher J Mathias,
Neurology 2014 Jun;
PMID: 24944260 [PubMed - as supplied by publisher]


T313M polymorphism of the PINK1 gene in Parkinson's disease.
Qin Luo, Xinling Yang, Yani Yao, Hongjuan Li, Yuling Wang
Exp Ther Med 2014 Jul; 8(1):286-290
PMID: 24944636 [PubMed - as supplied by publisher]


Frontotemporal dementia and its subtypes: a genome-wide association study.
Raffaele Ferrari, Dena G Hernandez, Michael A Nalls, Jonathan D Rohrer, Adaikalavan Ramasamy, John B J Kwok, Carol Dobson-Stone, William S Brooks, Peter R Schofield, Glenda M Halliday, John R Hodges, Olivier Piguet, Lauren Bartley, Elizabeth Thompson, Eric Haan, Isabel Hernández, Agustín Ruiz, Mercč Boada, Barbara Borroni, Alessandro Padovani, Carlos Cruchaga, Nigel J Cairns, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Gianluigi Forloni, Daniela Galimberti, Chiara Fenoglio, Maria Serpente, Elio Scarpini, Jordi Clarimón, Alberto Lleó, Rafael Blesa, Maria Landqvist Waldö, Karin Nilsson, Christer Nilsson, Ian R A Mackenzie, Ging-Yuek R Hsiung, David M A Mann, Jordan Grafman, Christopher M Morris, Johannes Attems, Timothy D Griffiths, Ian G McKeith, Alan J Thomas, P Pietrini, Edward D Huey, Eric M Wassermann, Atik Baborie, Evelyn Jaros, Michael C Tierney, Pau Pastor, Cristina Razquin, Sara Ortega-Cubero, Elena Alonso, Robert Perneczky, Janine Diehl-Schmid, Panagiotis Alexopoulos, Alexander Kurz, Innocenzo Rainero, Elisa Rubino, Lorenzo Pinessi, Ekaterina Rogaeva, Peter St George-Hyslop, Giacomina Rossi, Fabrizio Tagliavini, Giorgio Giaccone, James B Rowe, Johannes C M Schlachetzki, James Uphill, John Collinge, Simon Mead, Adrian Danek, Vivianna M Van Deerlin, Murray Grossman, John Q Trojanowski, Julie van der Zee, William Deschamps, Tim Van Langenhove, Marc Cruts, Christine Van Broeckhoven, Stefano F Cappa, Isabelle Le Ber, Didier Hannequin, Véronique Golfier, Martine Vercelletto, Alexis Brice, Benedetta Nacmias, Sandro Sorbi, Silvia Bagnoli, Irene Piaceri, Jřrgen E Nielsen, Lena E Hjermind, Matthias Riemenschneider, Manuel Mayhaus, Bernd Ibach, Gilles Gasparoni, Sabrina Pichler, Wei Gu, Martin N Rossor, Nick C Fox, Jason D Warren, Maria Grazia Spillantini, Huw R Morris, Patrizia Rizzu, Peter Heutink, Julie S Snowden, Sara Rollinson, Anna Richardson, Alexander Gerhard, Amalia C Bruni, Raffaele Maletta, Francesca Frangipane, Chiara Cupidi, Livia Bernardi, Maria Anfossi, Maura Gallo, Maria Elena Conidi, Nicoletta Smirne, Rosa Rademakers, Matt Baker, Dennis W Dickson, Neill R Graff-Radford, Ronald C Petersen, David Knopman, Keith A Josephs, Bradley F Boeve, Joseph E Parisi, William W Seeley, Bruce L Miller, Anna M Karydas, Howard Rosen, John C van Swieten, Elise G P Dopper, Harro Seelaar, Yolande A L Pijnenburg, Philip Scheltens, Giancarlo Logroscino, Rosa Capozzo, Valeria Novelli, Annibale A Puca, Massimo Franceschi, Alfredo Postiglione, Graziella Milan, Paolo Sorrentino, Mark Kristiansen, Huei-Hsin Chiang, Caroline Graff, Florence Pasquier, Adeline Rollin, Vincent Deramecourt, Florence Lebert, Dimitrios Kapogiannis, Luigi Ferrucci, Stuart Pickering-Brown, Andrew B Singleton, John Hardy, Parastoo Momeni
Lancet Neurol 2014 Jul; 13(7):686-99
PMID: 24943344 [PubMed - as supplied by publisher]


Arsenite Stress Downregulates Phosphorylation and 14-3-3 Binding of Leucine-rich Repeat Kinase 2 (LRRK2) Promoting Self-Association and Cellular Redistribution.
Adamantios Mamais, Ruth Chia, Alexandra Beilina, David N Hauser, Christine Hall, Patrick A Lewis, Mark R Cookson, Rina Bandopadhyay
J Biol Chem 2014 Jun;
PMID: 24942733 [PubMed - as supplied by publisher]


Fibroblast growth factor 20 (FGF20) gene polymorphism and risk of Parkinson's disease: a meta-analysis.
Ruixia Zhu, Ying Zhu, Xu Liu, Zhiyi He
Neurol Sci 2014 Jun;
PMID: 24942208 [PubMed - as supplied by publisher]


Immunostaining of Oxidized DJ-1 in Human and Mouse Brains.
Yoshiro Saito, Tomohiro Miyasaka, Hiroyuki Hatsuta, Kazuko Takahashi-Niki, Kojiro Hayashi, Yuichiro Mita, Osamu Kusano-Arai, Hiroko Iwanari, Hiroyoshi Ariga, Takao Hamakubo, Yasukazu Yoshida, Etsuo Niki, Shigeo Murayama, Yasuo Ihara, Noriko Noguchi
J Neuropathol Exp Neurol 2014 Jul; 73(7):714-28
PMID: 24918637 [PubMed - as supplied by publisher]


Freezing beyond gait in Parkinson's disease: A review of current neurobehavioral evidence.
S Vercruysse, M Gilat, J M Shine, E Heremans, S Lewis, A Nieuwboer
Neurosci Biobehav Rev 2014 Jun; 43C:213-227
PMID: 24769288 [PubMed - as supplied by publisher]


Rotigotine is safe and efficacious in Atypical Parkinsonism Syndromes induced by both ?-synucleinopathy and tauopathy.
Davide Vito Moretti, Giuliano Binetti, Orazio Zanetti, Giovanni Battista Frisoni
Neuropsychiatr Dis Treat 2014 ; 10:1003-9
PMID: 24940065 [PubMed - as supplied by publisher]


Solving the puzzle of Parkinson's disease using induced pluripotent stem cells.
Ping Zhao, Zhiwei Luo, Weihua Tian, Jiayin Yang, David P Ibáńez, Zhijian Huang, Micky D Tortorella, Miguel A Esteban, Wenxia Fan
Exp Biol Med (Maywood) 2014 Jun;
PMID: 24939824 [PubMed - as supplied by publisher]


Implication of dopamine D3 receptor activation in the reversion of Parkinson's disease-related motivational deficits.
S Carnicella, G Drui, S Boulet, C Carcenac, M Favier, T Duran, M Savasta
Transl Psychiatry 2014 ; 4:e401
PMID: 24937095 [PubMed - as supplied by publisher]


PINK1 deficiency in b-cells increases basal insulin secretion and improves glucose tolerance in mice.
Emma Deas, Kaisa Piipari, Asif Machhada, Abi Li, Ana Gutierrez-del-Arroyo, Dominic J Withers, Nicholas W Wood, Andrey Y Abramov
Open Biol 2014 May; 4(5):140051
PMID: 24941499 [PubMed - as supplied by publisher]


Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer's disease.
Angela Trovato Salinaro, Carolin Cornelius, Guido Koverech, Angela Koverech, Maria Scuto, Francesca Lodato, Vincenzo Fronte, Vera Muccilli, Michele Reibaldi, Antonio Longo, Maurizio G Uva, Vittorio Calabrese
Front Pharmacol 2014 ; 5:129
PMID: 24936186 [PubMed - as supplied by publisher]


Anatomic correlates of deep brain stimulation electrode impedance.
David Satzer, Eric W Maurer, David Lanctin, Weihua Guan, Aviva Abosch
J Neurol Neurosurg Psychiatry 2014 Jun;
PMID: 24935985 [PubMed - as supplied by publisher]


Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.
Elena Dragicevic, Christina Poetschke, Johanna Duda, Falk Schlaudraff, Stephan Lammel, Julia Schiemann, Michael Fauler, Andrea Hetzel, Masahiko Watanabe, Rafael Lujan, Robert C Malenka, Joerg Striessnig, Birgit Liss
Brain 2014 Jun;
PMID: 24934288 [PubMed - as supplied by publisher]


Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption.
Pamela Lopert, Manisha Patel
Redox Biol 2014 ; 2:667-72
PMID: 24936441 [PubMed - as supplied by publisher]


12q24 locus association with type 1 diabetes: SH2B3 or ATXN2?
Georg Auburger, Suzana Gispert, Suna Lahut, Ozgür Omür, Ewa Damrath, Melanie Heck, Nazl? Ba?ak
World J Diabetes 2014 Jun; 5(3):316-27
PMID: 24936253 [PubMed - as supplied by publisher]


The H50Q mutation enhances ?-synuclein aggregation, secretion and toxicity.
Ossama Khalaf, Bruno Fauvet, Abid Oueslati, Igor Dikiy, Anne-Laure Mahul-Mellier, Francesco Simone Ruggeri, Martial Mbefo, Filip Vercruysse, Giovanni Dietler, Seung-Jae Lee, David Eliezer, Hilal A Lashuel
J Biol Chem 2014 Jun;
PMID: 24936070 [PubMed - as supplied by publisher]


Semantic trouble sources and their repair in conversations affected by Parkinson's disease.
Charlotta Saldert, Ulrika Ferm, Steven Bloch
Int J Lang Commun Disord 2014 Jun;
PMID: 24934292 [PubMed - as supplied by publisher]


Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson's disease (PD COMM pilot): study protocol for a randomized controlled trial.
Catherine M Sackley, Christina H Smith, Caroline Rick, Marian C Brady, Natalie Ives, Ramilla Patel, Helen Roberts, Francis Dowling, Sue Jowett, Keith Wheatley, Smitaa Patel, Debbie Kelly, Gina Sands, Carl Clarke
Trials 2014 ; 15(1):213
PMID: 24908096 [PubMed - as supplied by publisher]


GSK-3 as potential target for therapeutic intervention in cancer.
James A McCubrey, Linda S Steelman, Fred E Bertrand, Nicole M Davis, Melissa Sokolosky, Steve L Abrams, Giuseppe Montalto, Antonino B D'Assoro, Massimo Libra, Ferdinando Nicoletti, Roberta Maestro, Jorg Basecke, Dariusz Rakus, Agnieszka Gizak, Zoya N Demidenko, Lucio Cocco, Alberto M Martelli, Melchiorre Cervello
Oncotarget 2014 May; 5(10):2881-911
PMID: 24931005 [PubMed - as supplied by publisher]


Could deep brain stimulation help with driving for patients with Parkinson's?
Carsten Buhmann, Christian Gerloff
Expert Rev Med Devices 2014 Jun; :1-3
PMID: 24930934 [PubMed - as supplied by publisher]


Select E2 enzymes differentially regulate parkin activation and mitophagy.
Fabienne C Fiesel, Elisabeth L Moussaud-Lamodičre, Maya Ando, Wolfdieter Springer
J Cell Sci 2014 Jun;
PMID: 24928900 [PubMed - as supplied by publisher]


Military-related traumatic brain injury and neurodegeneration.
Ann C McKee, Meghan E Robinson
Alzheimers Dement 2014 Jun; 10(3 Suppl):S242-53
PMID: 24924675 [PubMed - as supplied by publisher]


The disease intersection of susceptibility and exposure: Chemical exposures and neurodegenerative disease risk.
Caroline M Tanner, Samuel M Goldman, G Webster Ross, Stephen J Grate
Alzheimers Dement 2014 Jun; 10(3 Suppl):S213-25
PMID: 24924672 [PubMed - as supplied by publisher]


DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease.
M J Barallobre, C Perier, J Bové, A Laguna, J M Delabar, M Vila, M L Arbonés
Cell Death Dis 2014 ; 5:e1289
PMID: 24922073 [PubMed - as supplied by publisher]


The frequency and severity of gastrointestinal symptoms in patients with early Parkinson's disease.
Hye-Young Sung, Jeong-Wook Park, Joong-Seok Kim
J Mov Disord 2014 Apr; 7(1):7-12
PMID: 24926404 [PubMed - as supplied by publisher]


Visual short-term memory deficits associated with GBA mutation and Parkinson's disease.
Nahid Zokaei, Alisdair McNeill, Christos Proukakis, Michelle Beavan, Paul Jarman, Prasad Korlipara, Derralynn Hughes, Atul Mehta, Michele T M Hu, Anthony H V Schapira, Masud Husain
Brain 2014 Jun;
PMID: 24919969 [PubMed - as supplied by publisher]


iPLA2? Knockout Mouse, a Genetic Model for Progressive Human Motor Disorders, Develops Age-Related Neuropathology.
Helene Blanchard, Ameer Y Taha, Yewon Cheon, Hyung-Wook Kim, John Turk, Stanley I Rapoport
Neurochem Res 2014 Jun;
PMID: 24919816 [PubMed - as supplied by publisher]


Allopregnanolone and neuroinflammation: a focus on multiple sclerosis.
Farshid Noorbakhsh, Glen B Baker, Christopher Power
Front Cell Neurosci 2014 ; 8:134
PMID: 24917787 [PubMed - as supplied by publisher]


In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2.
Renée Vancraenenbroeck, Joren De Raeymaecker, Evy Lobbestael, Fangye Gao, Marc De Maeyer, Arnout Voet, Veerle Baekelandt, Jean-Marc Taymans
Front Mol Neurosci 2014 ; 7:51
PMID: 24917786 [PubMed - as supplied by publisher]


Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson's disease mutant of Leucine-rich repeat kinase 2 (LRRK2).
Radek Linhart, Sarah Anne Wong, Jieyun Cao, Melody Tran, Anne Huynh, Casey Ardrey, Jong Min Park, Christine Hsu, Saher Taha, Rentia Peterson, Shannon Shea, Jason Kurian, Katerina Venderova
Mol Neurodegener 2014 Jun; 9(1):23
PMID: 24915984 [PubMed - as supplied by publisher]


Caffeine Interaction with Glutamate Receptor Gene GRIN2A: Parkinson's Disease in Swedish Population.
Naomi Yamada-Fowler, Mats Fredrikson, Peter Söderkvist
PLoS One 2014 ; 9(6):e99294
PMID: 24915238 [PubMed - as supplied by publisher]


Relationship between acoustic measures and judgments of intelligibility in Parkinson's disease: A within-speaker approach.
Lynda Feenaughty, Kris Tjaden, Joan Sussman
Clin Linguist Phon 2014 May; :1-22
PMID: 24874184 [PubMed - as supplied by publisher]


Fluency in Parkinson?s disease: disease duration, cognitive status and age.
Natalia Casagrande Brabo, Thais Soares C Minett, Karin Zazo Ortiz
Arq Neuropsiquiatr 2014 May; 72(5):349-55
PMID: 24863510 [PubMed - as supplied by publisher]


Communicative strategies used by spouses of individuals with communication disorders related to stroke-induced aphasia and Parkinson's disease.
Emilia Carlsson, Lena Hartelius, Charlotta Saldert
Int J Lang Commun Disord 2014 May;
PMID: 24861715 [PubMed - as supplied by publisher]


Assessing speech dysfunction using BOLD and acoustic analysis in parkinsonism.
Mohit Saxena, Madhuri Behari, S Senthil Kumaran, Vinay Goyal, Vaishna Narang
Parkinsonism Relat Disord 2014 May;
PMID: 24857769 [PubMed - as supplied by publisher]


Efficacy of language-appropriate cueing on micrographia in Korean patients with Parkinson's disease.
HyangHee Kim, Ji Hye Yoon, Hyo Suk Nam
Geriatr Gerontol Int 2014 May;
PMID: 24852208 [PubMed - as supplied by publisher]


Cepstral Analysis of Hypokinetic and Ataxic Voices: Correlations With Perceptual and Other Acoustic Measures.
Stephen Jannetts, Anja Lowit
J Voice 2014 May;
PMID: 24836365 [PubMed - as supplied by publisher]


Long-term outcome of subthalamic nucleus deep brain stimulation for Parkinson's disease using an MRI-guided and MRI-verified approach.
Iciar Aviles-Olmos, Zinovia Kefalopoulou, Elina Tripoliti, Joseph Candelario, Harith Akram, Irene Martinez-Torres, Marjan Jahanshahi, Thomas Foltynie, Marwan Hariz, Ludvic Zrinzo, Patricia Limousin
J Neurol Neurosurg Psychiatry 2014 Apr;
PMID: 24790212 [PubMed - as supplied by publisher]


Vocalization deficits in mice over-expressing alpha-synuclein, a model of pre-manifest Parkinson's disease.
Laura M Grant, Franziska Richter, Julie E Miller, Stephanie A White, Cynthia M Fox, Chunni Zhu, Marie-Francoise Chesselet, Michelle R Ciucci
Behav Neurosci 2014 Apr; 128(2):110-21
PMID: 24773432 [PubMed - as supplied by publisher]