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Alzheimers Dement 2014 Feb; 10(1S):S38-S46
Authors: Thomas Foltynie, Iciar Aviles-Olmos
There is an increasing number of approaches to try and relieve the motor symptoms of†Parkinson's disease (PD) that focus predominantly on strategies of dopaminergic replacement or deep brain stimulation. There remains, however, a major need to slow down or reverse the relentless progression of the disease to prevent the evolution of disabling motor and nonmotor features that continue to cause disability despite the existing symptomatic approaches. Data emerging from the laboratory suggest that agonists for the glucagonlike peptide 1 (GLP-1) receptor may have biological properties relevant to PD pathogenesis and progression.
PMID: 24529524 [PubMed - as supplied by publisher]