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Randomized clinical trial of topiramate for levodopa-induced dyskinesia in Parkinson's disease.
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Parkinsonism Relat Disord 2014 Jan;
Authors: Christopher Kobylecki, David J Burn, Lewis Kass-Iliyya, Mark W Kellett, Alan R Crossman, Monty A Silverdale
The antiepileptic drug topiramate reduces levodopa-induced dyskinesia without exacerbating parkinsonism in animal models. We report a randomized, double-blind, placebo-controlled crossover trial in patients with Parkinson's disease and levodopa-induced dyskinesia.
PMID: 24521874 [PubMed - as supplied by publisher]