When telephone lines go down, or Internet connections are lost, our communities temporarily come to a halt. What if something similar were found to be happening in Parkinson's? This is the focus of Dr. Schmitz and her team at the PDF Research Center at Columbia University Medical Center.
PDF Grant Programs
Are you interested in furthering Parkinson's science? View PDF's open grant programs.
Using EEG spatial correlation, cross frequency energy, and wavelet coefficients for the prediction of Freezing of Gait in Parkinson's Disease patients.
PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research.
Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members? Please browse PDF's educational materials and programs - which are all available electronically or in print. Order for yourself, a loved one or in bulk for your patients or support group.
Conf Proc IEEE Eng Med Biol Soc 2013 Jul; 2013:4263-6
Authors: A M Ardi Handojoseno, James M Shine, Tuan N Nguyen, Yvonne Tran, Simon J G Lewis, Hung T Nguyen
Parkinson's Disease (PD) patients with Freezing of Gait (FOG) often experience sudden and unpredictable failure in their ability to start or continue walking, making it potentially a dangerous symptom. Emerging knowledge about brain connectivity is leading to new insights into the pathophysiology of FOG and has suggested that electroencephalogram (EEG) may offer a novel technique for understanding and predicting FOG. In this study we have integrated spatial, spectral, and temporal features of the EEG signals utilizing wavelet coefficients as our input for the Multilayer Perceptron Neural Network and k-Nearest Neighbor classifier. This approach allowed us to predict transition from walking to freezing with 87 % sensitivity and 73 % accuracy. This preliminary data affirms the functional breakdown between areas in the brain during FOG and suggests that EEG offers potential as a therapeutic strategy in advanced PD.
PMID: 24110674 [PubMed - as supplied by publisher]