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Fosmn: facial onset sensory motor neuronopathy. A 'benign' differential diagnosis to bulbar onset motor neuron disease. The first cohort from the uk.
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J Neurol Neurosurg Psychiatry 2013 Nov; 84(11):e2
Authors: Besa Ziso, Tim Williams, Jon Walters, Stephan Jaiser, Udo Wieshmann, Anu Jacob
Walton Centre for Neurology and Neurosurgery; Newcastle Upon Tyne NHS Foundation Trust; Morriston Hospital, Swansea.
Facial onset sensory motor neuronopathy (FOSMN) is a rare, slowly progressive bulbar onset motor and sensory neuronopathy. Described only in 2006, it is still under-recognised with fewer than 20 cases reported in world literature. Although there are marked similarities to classical bulbar onset MND, FOSMN is set apart clinically by the striking facial-onset sensory deficits with subsequent development of motor deficits, slow evolution in a rostral-caudal direction and a much better prognosis.
PMID: 24108993 [PubMed - as supplied by publisher]