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Selective use of low frequency stimulation in Parkinson's disease based on absence of tremor.
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NeuroRehabilitation 2013 Jan; 33(2):305-12
Authors: Elizabeth L StegemŲller, Srikant Vallabhajosula, Ihtsham Haq, Nelson Hwynn, Chris J Hass, Michael S Okun
Department of Applied Physiology and Kinesiology and Center for Movement Disorders & Neurorestoration, University of Florida, Gainesville, FL, USA.
High frequency stimulation (HFS) of the subthalamic nucleus is one of the most effective treatments for advanced Parkinson's disease (PD). HFS has provided beneficial improvements in the cardinal features of PD, but has not been proven as effective for addressing the axial predominant levodopa resistant symptoms, such as speech disturbances, gait disturbances, and postural instability. Recent studies have suggested that changes in stimulation parameters may influence differing PD symptoms.
PMID: 23949053 [PubMed - as supplied by publisher]