Adjust Text Size:change font sizechange font sizechange font sizechange font sizechange font sizechange font size

Featured Research

Can we predict who is at risk of facing cognitive issues in PD and address them earlier? These are the questions being pursued by Dr. Goldman of the PDF Research Center at Rush University Medical Center.

Learn More

PDF Grant Programs

Are you interested in furthering Parkinson's science? View PDF's open grant programs.

Learn More


0239? Inducible nitric oxide synthase gene methylation and parkinsonism in manganese-exposed welders0239? Inducible nitric oxide synthase gene methylation and parkinsonism in manganese-exposed welders.

PDF's targeted PubMed search provides you with access to journal articles from the last 90 days that may be pertinent to Parkinson's disease research. 

Not what you're looking for? Do you need informational publications about Parkinson's targeted for people living with Parkinson's, caregivers and family members?  Please browse PDF's educational materials and programs - which are all available electronically or in print.  Order for yourself, a loved one or in bulk for your patients or support group.

Occup Environ Med 2014 Jun; 71 Suppl 1:A32

Authors: Susan Nielsen, Harvey Checkoway, Susan Criswell, Federico Farin, Brad Racette

To assess whether parkinsonism in manganese (Mn)-exposed welders is associated with methylation of NOS2, a methylation-regulated gene that codes for inducible nitric oxide synthase (iNOS). We hypothesised that parkinsonian welders would have lower NOS2 methylation than other welders, consistent with greater iNOS activity and an inflammatory pathogenesis.

PMID: 25018322 [PubMed - as supplied by publisher]

See More

Back to PubMed Articles