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Cognitive deficits in mild Parkinson's disease are associated with distinct areas of grey matter atrophy.
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J Neurol Neurosurg Psychiatry 2013 Oct;
Authors: Elijah Mak, Juan Zhou, Louis C S Tan, Wing Lok Au, Yih Yian Sitoh, Nagaendran Kandiah
Department of Neurology, National Neuroscience Institute, Singapore.
The neuroanatomical substrates underlying cognitive impairment in Parkinson's disease (PD) remain poorly understood. To address this gap, we compared the grey matter atrophy patterns in PD patients with mild cognitive impairment (PD-MCI) with PD patients having no cognitive impairment (PD-NCI), and examined relationships between atrophic regions and cognitive performance in specific domains.
PMID: 24133286 [PubMed - as supplied by publisher]